Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionintramolecular transferase activity

PUS1 LSS

1.11e-0329342GO:0016866
GeneOntologyMolecularFunctioncatalytic activity, acting on a tRNA

GATB PUS1 TARBP1

1.87e-03144343GO:0140101
DomainEMI

SSPOP MEGF10

3.81e-0417322PS51041
DomainRUN

SNX29 RUSC2

4.28e-0418322SM00593
DomainRUN

SNX29 RUSC2

4.78e-0419322PS50826
DomainRun_dom

SNX29 RUSC2

4.78e-0419322IPR004012
DomainRUN

SNX29 RUSC2

4.78e-0419322PF02759
DomainTSP_1

ADGRB3 SSPOP

5.20e-0363322PF00090
DomainTSP1

ADGRB3 SSPOP

5.53e-0365322SM00209
DomainTSP1_rpt

ADGRB3 SSPOP

5.53e-0365322IPR000884
DomainTSP1

ADGRB3 SSPOP

5.53e-0365322PS50092
DomainEGF_1

FN1 SSPOP MEGF10

9.32e-03255323PS00022
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

DISP2 NOTUM

4.86e-057222MM15187
PathwayREACTOME_RELEASE_OF_HH_NP_FROM_THE_SECRETING_CELL

DISP2 NOTUM

6.47e-058222M27444
Pubmed

The murine dilute suppressor gene encodes a cell autonomous suppressor.

FN1 HPS6

6.02e-05113727828830
Pubmed

Transcriptional profiling of Wnt3a mutants identifies Sp transcription factors as essential effectors of the Wnt/β-catenin pathway in neuromesodermal stem cells.

FN1 NOTUM

7.22e-051237224475213
Pubmed

Genetic correlates of brain aging on MRI and cognitive test measures: a genome-wide association and linkage analysis in the Framingham Study.

GATB TARBP1

1.31e-041637217903297
Pubmed

Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation.

LSS FA2H

3.25e-042537232266943
Pubmed

The influence of genetic variation in 30 selected genes on the clinical characteristics of early onset breast cancer.

FN1 MAP3K1

4.39e-042937219094228
Pubmed

Genome-wide contribution of genotype by environment interaction to variation of diabetes-related traits.

SNX29 MAP3K1

5.69e-043337224204828
Pubmed

Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.

FN1 SSPOP PRG2

8.58e-0417537328071719
Cytoband10q24.32

C10orf95 HPS6

1.82e-042438210q24.32
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

SYNM ACBD3

6.15e-0429232396
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

DIPK1C PTGER2 TARBP1 FA2H RUSC2

1.83e-071513858ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell-Renin-positive_Juxtaglomerular_Granular_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 RELT FN1 PTGER2 SYNM

2.76e-0716438543630a448f4369fa9e4e3eccdf3b9f29cec16c39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 RELT FN1 PTGER2 SYNM

2.76e-07164385108fbecb56d69a675d6ce6e826a873ae528f2fd7
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal--glomerular_mesenchymal_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADGRB3 RELT FN1 PTGER2 SYNM

2.76e-0716438546208f18325976c89f572f6627aea0582142b92d
ToppCellEndothelial-B-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

APOLD1 SYNM SSPOP KCNF1

1.20e-05166384c286987ea4e511195607c87ec4529c2c2ed2122e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_low-phase|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

GATB FBXL19-AS1 APOLD1 FANCA

1.41e-05173384506efcaa5afd6ed5e565c4c4def6a4505fea97c5
ToppCell15-Trachea-Mesenchymal-Mesenchyme_RSPO2+|Trachea / Age, Tissue, Lineage and Cell class

LSS FN1 NOTUM APOLD1

1.44e-05174384fa0681e91724b9a51ee28b214ea5aa14e62ba1a3
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Activated_DCs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

DISP2 NOTUM SNX29 MAP3K1

1.64e-05180384aae85fb3c92a45614616a3ee3a1af5244cc299a7
ToppCelldroplet-Lung-nan-21m-Mesenchymal-pulmonary_interstitial_fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGER2 NOTUM TMEM158 MEGF10

1.75e-0518338419e7be1cfdd111bfb840532a6f7c780345dffccf
ToppCelldroplet-Lung-nan-21m-Mesenchymal-Myofibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTGER2 NOTUM TMEM158 MEGF10

1.75e-05183384b153425ab0df1e5fa9b953e1f6d4e8e3dc6621b0
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell-pulmonary_interstitial_myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTGER2 NOTUM TMEM158 MEGF10

1.99e-05189384cd42ce4aa217d0bd95e0cc0ba357bdfeb3e55a48
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast-myofibroblast_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTGER2 NOTUM TMEM158 MEGF10

1.99e-05189384102501eee7760d5882dec41ea9d00147b3f4fb73
ToppCelldroplet-Lung-21m-Mesenchymal-myofibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PTGER2 NOTUM TMEM158 MEGF10

1.99e-051893846e83bf855d4771885b60bb8992df2f9b508eef97
Diseaseglomerulonephritis (is_marker_for)

FN1 KLKB1

2.18e-0419342DOID:2921 (is_marker_for)
Diseaseinterleukin 16 measurement

KLKB1 PRG2

7.92e-0436342EFO_0008173
Diseaseesophagus squamous cell carcinoma (is_implicated_in)

MAP3K1 FANCA

1.24e-0345342DOID:3748 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
WCGCRRQRGTERGAG

C17orf114

11

A0A1B0GUV1
CRDGGRGLERRHGRW

LINC00696

36

Q6ZRV3
CDGGWERRIRTCQGA

ADGRB3

471

O60242
QACRGANRGELWVRD

CASP4

256

P49662
RGRRWAFARVDGGSC

GATB

11

O75879
GCARRARGRWEGSAP

DISP2

651

A7MBM2
ARGTRKARAGAWRGC

APOLD1

11

Q96LR9
AGFRGWRCEDRCEQG

MEGF10

171

Q96KG7
LARRWRGDVGCSAGR

PTGER2

46

P43116
DLGRWRLNCERGRQT

LSS

21

P48449
GGAAEEARRLEQRWG

ACBD3

66

Q9H3P7
CAGGSEGRKTWRRRG

NOTUM

16

Q6P988
QVWIGGRITGSGRCR

PRG2

156

P13727
VQRRLAAGACWVRRG

FA2H

16

Q7L5A8
YRQRWRLQGRGDCDM

FBXL19-AS1

71

Q494R0
QRGWRCDNCRRPGGE

FN1

2416

P02751
GGRRRAWAELLAGRV

FANCA

16

O15360
RLVGITSWGEGCARR

KLKB1

591

P03952
GRRAWAAQVEERRGR

CCDC177

391

Q9NQR7
GRLVWCEERQARAEG

HPS6

136

Q86YV9
AGWCRRRGRCGRGTL

DIPK1C

11

Q0P6D2
EAGSGGRERADWRRR

MAP3K1

46

Q13233
VLGRAGGDWLRCSRG

RUSC2

1476

Q8N2Y8
DVGRGRAWLRCALNE

SNX29

111

Q8TEQ0
GFRLRWREAEALCGG

SSPOP

4636

A2VEC9
RRGREGLWAEGQARC

SYNM

46

O15061
RRSCSGRAGGDRVWE

PUS1

46

Q9Y606
RGWRTGVQRGCGLRL

MRPL49

11

Q13405
LASCGGDRRIRIWGT

CIAO1

31

O76071
WPRAGRRGRRAGACK

C10orf95

151

Q9H7T3
RLCVGCGWVRGRRTG

TMEM158

141

Q8WZ71
RRDTAGWKICREGNG

STARD5

21

Q9NSY2
VGRRNGRAVDRAIGW

TUG1

11

A0A6I8PU40
LGTHGCDEWGRRARR

RELT

116

Q969Z4
CDEWGRRARRGVEVA

RELT

121

Q969Z4
GAREAGPDARRCWRF

TARBP1

251

Q13395
ASGRRIWIRRAGGRC

TGM6

466

O95932
GRCGGRRCLRRWFHF

TRPM4

761

Q8TD43
DLGVDAAEGRWRRCQ

KCNF1

151

Q9H3M0