Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessglycoside transport

ABCC3 SLC5A2

1.65e-055272GO:1901656
DomainEGF_CA

MASP1 STAB2 OIT3 DLL4

2.71e-05122274SM00179
DomainEGF-like_Ca-bd_dom

MASP1 STAB2 OIT3 DLL4

2.89e-05124274IPR001881
DomainEGF_3

MASP1 STAB2 OIT3 DLL4

3.41e-04235274PS50026
DomainASX_HYDROXYL

MASP1 OIT3 DLL4

3.97e-04100273PS00010
DomainEGF-like_dom

MASP1 STAB2 OIT3 DLL4

4.25e-04249274IPR000742
DomainEGF_1

MASP1 STAB2 OIT3 DLL4

4.65e-04255274PS00022
DomainEGF-type_Asp/Asn_hydroxyl_site

MASP1 OIT3 DLL4

4.71e-04106273IPR000152
DomainEGF_2

MASP1 STAB2 OIT3 DLL4

5.38e-04265274PS01186
DomainEGF_extracell

STAB2 DLL4

3.38e-0360272IPR013111
DomainEGF_2

STAB2 DLL4

3.38e-0360272PF07974
DomainLIM

PRICKLE4 CRIP3

4.45e-0369272PF00412
Domain-

PRICKLE4 CRIP3

4.57e-03702722.10.110.10
DomainEGF

STAB2 OIT3 DLL4

4.60e-03235273SM00181
DomainLIM_DOMAIN_2

PRICKLE4 CRIP3

4.70e-0371272PS50023
DomainZnf_LIM

PRICKLE4 CRIP3

4.70e-0371272IPR001781
DomainLIM_DOMAIN_1

PRICKLE4 CRIP3

4.70e-0371272PS00478
DomainLIM

PRICKLE4 CRIP3

4.70e-0371272SM00132
DomainEGF-like_CS

MASP1 STAB2 DLL4

6.16e-03261273IPR013032
DomainEGF_Ca-bd_CS

MASP1 OIT3

8.61e-0397272IPR018097
DomainEGF_CA

MASP1 OIT3

8.96e-0399272PS01187
DomainEGF

STAB2 DLL4

1.42e-02126272PF00008
Pubmed

Sodium Intake Regulates Glucose Homeostasis through the PPARĪ“/Adiponectin-Mediated SGLT2 Pathway.

ADIPOQ SLC5A2

5.80e-06527227053360
Pubmed

Novel loci for adiponectin levels and their influence on type 2 diabetes and metabolic traits: a multi-ethnic meta-analysis of 45,891 individuals.

ADIPOQ ATP6V0A2

1.21e-042127222479202
Pubmed

Genome-wide data reveal novel genes for methotrexate response in a large cohort of juvenile idiopathic arthritis cases.

CHST11 STAB2

4.23e-043927224709693
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

ASPM ABCC3 MASP1 SNAPC3 DLL4 ATP6V0A2

4.53e-04132727632694731
Pubmed

Cytoplasmic Metadherin (MTDH) provides survival advantage under conditions of stress by acting as RNA-binding protein.

ABTB1 ABCC3 PRICKLE4

6.03e-0421427322199357
CytobandEnsembl 112 genes in cytogenetic band chr3q27

MASP1 ADIPOQ

2.59e-03128272chr3q27
CytobandEnsembl 112 genes in cytogenetic band chr12q23

CHST11 STAB2

3.53e-03150272chr12q23
GeneFamilyLIM domain containing

PRICKLE4 CRIP3

1.55e-03591821218
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 SLC5A2

1.10e-041552738fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellmild_COVID-19_(asymptomatic)-B_cell|World / disease group, cell group and cell class (v2)

ABCC3 CASZ1 TMEM40

1.17e-04158273afa8fa21c39c2192c1e23a4660011d63d58b733f
ToppCellmild_COVID-19_(asymptomatic)-B_cell|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)

ABCC3 CASZ1 TMEM40

1.30e-04164273e4d43af7eb04d55328791b554bdf3a7ce6818027
ToppCellE16.5-Endothelial-Endothelial_lymphatic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ST6GAL2 STAB2

1.38e-04167273b93103a868fba63a8910bffb690a6242b9252833
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ST6GAL2 STAB2

1.38e-0416727326cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ST6GAL2 STAB2

1.38e-04167273fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCellE16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PRICKLE4 ST6GAL2 STAB2

1.38e-04167273f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CROT CRIP3 CASZ1

1.45e-04170273fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCelldroplet-Lung-LUNG-30m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OIT3 MBOAT4 TMEM40

1.53e-041732734f849d236ee358ad30ac977745ac43c8e9778e94
ToppCelldroplet-Lung-LUNG-30m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

OIT3 MBOAT4 TMEM40

1.53e-0417327339c3b8313354c4c60764597507a2505dcfa4e8c7
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABTB1 OIT3 TMEM40

1.53e-04173273b2c55084ef6dac0e329c2e65c24cfe0045859c30
ToppCelldroplet-Lung-3m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABTB1 OIT3 TMEM40

1.53e-04173273120dd20e8a71f9169a1596b6171df7aa0b96dd15
ToppCelldroplet-Lung-30m-Hematologic-myeloid-Basophil/Mast_cell-basophil_l26|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

OIT3 MBOAT4 TMEM40

1.55e-04174273009e88a6c79689a5d88b0af50aa89aa03b33f800
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

PRICKLE4 CROT TMEM40

1.58e-041752730cc215109d9915af47e4d0a120ce2e46910715fa
ToppCelldroplet-Liver-Npc-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.61e-041762733494ffa8555e6edf4b1250e10434bae9b73ec845
ToppCelldroplet-Liver-Npc-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.61e-04176273d43f6b7828b98e1dab7b726a5f99499d65a7db80
ToppCelldroplet-Liver-nan-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.74e-04181273fcc94f04dae98b817ec06b282d2e887804d37ae5
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.77e-04182273000ff26c51c6a1ea8770c02722523e55be83b46f
ToppCellfacs-Liver-Liver_non-hepato/SCs_st|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.77e-04182273b906e6e584ecbe92d3030bbdc4426f244fbe0045
ToppCelldroplet-Liver-nan-3m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.80e-04183273709a486154b3157427deb3b8886b63ac39ea42dd
ToppCelldroplet-Liver-nan-3m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

1.80e-04183273dc06f19f6f80f4c7f13f1f990c1fe0f91ba64ea7
ToppCellmegakaryocytic|World / Lineage and Cell class

ABCC3 ST6GAL2 TMEM40

1.83e-04184273b1c630ca2189d9d49402a5621b57618976fbea5c
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

STAB2 OIT3 DLL4

1.89e-04186273f51c76b1c3c6c49e0ebc9a913d8413e0b6a04d80
ToppCellPCW_05-06-Endothelial-Endothelial_mature-lymphatic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

STAB2 OIT3 DLL4

1.89e-0418627386b218a400f9c64f92b050f00b49f09647b17437
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_aerocyte_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCC3 DLL4 CASZ1

1.95e-04188273db0652f000d459493321b53239326706eace598c
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Mature_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 OIT3 DLL4

1.98e-041892731d660bceee449aebf12fc9af4c74af246837b27a
ToppCellAdult|World / Lineage, Cell type, age group and donor

ABCC3 CHST11 CASZ1

1.98e-041892735cd285bfad973125d46d704fec18b21266a63379
ToppCell21-Trachea-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

STAB2 OIT3 DLL4

2.01e-04190273bce09634acbc2cfd53666328e8aed8bf8835f845
ToppCell21-Trachea-Endothelial-Endothelial|Trachea / Age, Tissue, Lineage and Cell class

STAB2 OIT3 DLL4

2.01e-0419027308437396a98ca9526f69c3a74bbf2929f3c68b8e
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.04e-0419127388f91e57a1409bdeb91e9bf47510a6fb998a1bf5
ToppCell10x5'v1-week_14-16-Hematopoietic-MK|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ST6GAL2 TMEM40 ATP6V0A2

2.04e-041912737edc22e7e70697fb22690699efb352577162709b
ToppCellE16.5-samps-Endothelial-Immature_fetal_endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

STAB2 DLL4 CASZ1

2.04e-0419127344c596984c6196f6014e0e405dbe5560841e54ff
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.04e-041912731924af7d8b0a0b892e480a9fd6d874941b0c0b5d
ToppCellE16.5-samps-Endothelial|E16.5-samps / Age Group, Lineage, Cell class and subclass

STAB2 DLL4 CASZ1

2.04e-04191273e7521d4d24f016d4e531cd492a7a69604f0c9e6f
ToppCellMegakaryocytic-erythropoietic-Megakaryo-cells-Platelet|Megakaryo-cells / Lineage, cell class and subclass

ABTB1 ABCC3 TMEM40

2.08e-04192273a061db719d87209b56d074afbdeab37aa0079419
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

ASPM CHST11 MUC6

2.08e-04192273a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.08e-041922735890076929598e88fe9d59a4e4e858b446746ce9
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.08e-04192273d525f7f088a53110912600a7c9f6d33b9270d534
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.08e-041922732bfac6b3956265205ca47d06888851ed68b65999
ToppCellRV-08._Macrophage|RV / Chamber and Cluster_Paper

ASPM CHST11 MUC6

2.11e-0419327312bf98a280f87e4d8f0c6887dfc855da72e47ac1
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.11e-041932734a8c97ff2dffc5c06351d1cb107e21e58250aa55
ToppCelldroplet-Liver-HEPATOCYTES-1m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.11e-04193273d5f6d6e2c36d4e80af4d39cdfc0b18df295a587b
ToppCellfacs-Liver-Non-hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.14e-04194273c8b9551b93a5aed62154b487db90130604a6125c
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.17e-0419527312ba6d95e42d06b1991b011043c0e3370a7b4131
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ST6GAL2 CROT TMEM40

2.17e-041952736c9c58322c1df891bb4bab56dacb542c8777bb7d
ToppCelldroplet-Liver-LIVER-NPC-1m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STAB2 OIT3 DLL4

2.17e-04195273126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCell3'-GW_trimst-2-LargeIntestine-Endothelial|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

STAB2 OIT3 DLL4

2.20e-041962739b53e3fdb23dbdfc2e7ce012c6b2ce50700c95d5
ToppCellBasal_cells-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ABCC3 CROT TMEM40

2.20e-041962733b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCellEpithelial_cells-Basal_cells|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id

ABCC3 CROT TMEM40

2.27e-041982734235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCC3 ST6GAL2 CROT

2.31e-0419927394a7867e800df352731796de8c24cba133c29622
Drugindomethacin, USP; Up 200; 100uM; PC3; HG-U133A

ABCC3 PISD CHST11 CROT SLC5A2

2.31e-06192265452_UP
DiseaseDeafness

PISD POLD1

2.04e-0425252C0011053
Diseasefatty liver disease (biomarker_via_orthology)

ABCC3 ADIPOQ

3.58e-0433252DOID:9452 (biomarker_via_orthology)
Diseaseend stage renal disease (biomarker_via_orthology)

ABCC3 ADIPOQ

7.28e-0447252DOID:783 (biomarker_via_orthology)
Diseasediabetic retinopathy (is_marker_for)

ADIPOQ DLL4

9.60e-0454252DOID:8947 (is_marker_for)
Diseasenon-alcoholic fatty liver disease (biomarker_via_orthology)

ABCC3 ADIPOQ

1.39e-0365252DOID:0080208 (biomarker_via_orthology)
Diseasestem Cell Growth Factor beta measurement

CHST11 STAB2

1.84e-0375252EFO_0008292
Diseasepancreatic cancer (is_marker_for)

ABCC3 MUC6

3.31e-03101252DOID:1793 (is_marker_for)

Protein segments in the cluster

PeptideGeneStartEntry
PLDDCSVYYHGCHLN

CASZ1

531

Q86V15
HCNIPGLYYFAYHIT

ADIPOQ

151

Q15848
YHCLCPPGYYGLHCE

DLL4

346

Q9NR61
IYGRIIPCKHAFCYH

CBLL2

66

Q8N7E2
GRVLCYLIHHYHPCY

ASPM

1141

Q8IZT6
SPRYLYVCHYCHEGN

CRISP1

166

P54107
CYLLYLRHHCRGYII

ABCC3

51

O15438
TCHSKVYHLPYYEAC

MUC6

1071

Q6W4X9
VYHLPYYEACVRDAC

MUC6

1076

Q6W4X9
PSVCFHVYCGHFYDI

OIT3

136

Q8WWZ8
LIYFYHDGQLYCGRH

PRICKLE4

126

Q2TBC4
HDGVPYCHVPCYGYL

CRIP3

166

Q6Q6R5
LCHLGLHYTEYYLHE

MBOAT4

96

Q96T53
LSCDHYCHNYIGGYY

MASP1

151

P48740
SVCCHIHGFAPYFYT

POLD1

136

P28340
LAYYRLHGHPGCCYE

CROT

426

Q9UKG9
CHYHELYYDAACTLG

ST6GAL2

466

Q96JF0
GFPYLYCHQGDCEHV

SNAPC3

306

Q92966
YYACLCGHEELVLYL

ABTB1

41

Q969K4
CHPCHIHYDLVGKYE

CHST11

266

Q9NPF2
YHCYHEKDPDGCYRL

COA7

26

Q96BR5
ACPAFLCGVHYLYFA

SLC5A2

516

P31639
LYHCVIYLAPGDYHC

PISD

251

Q9UG56
LCFAIGALLVCYHYY

TMEM40

166

Q8WWA1
GPYVQFCHIHATCEY

STAB2

831

Q8WWQ8
PSDNLLHYCYVHCYL

VPS13B

721

Q7Z7G8
LHYCYVHCYLKIFGF

VPS13B

726

Q7Z7G8
THFCPLCDYSGYLRH

ZNF142

1256

P52746
ICDCYHCHVYPYPNT

ATP6V0A2

241

Q9Y487