Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	zinc ion binding	TRIM43B ZNF330 NFX1 ADAMTS20 CZIB TRIM43 ZMAT4 ZDBF2 NR6A1 USP3 ZMYM6 NUP153	1.13e-04	891	75	12	GO:0008270
GeneOntologyMolecularFunction	cytoskeleton-nuclear membrane anchor activity	SYNE1 SYNE2	1.38e-04	5	75	2	GO:0140444
GeneOntologyMolecularFunction	transition metal ion binding	TRIM43B ZNF330 NFX1 CYP4X1 ADAMTS20 CZIB TRIM43 ZMAT4 ZDBF2 NR6A1 USP3 ZMYM6 NUP153	4.44e-04	1189	75	13	GO:0046914
GeneOntologyMolecularFunction	protein-membrane adaptor activity	SYNE1 SYNE2 NUP153	6.45e-04	45	75	3	GO:0043495
GeneOntologyCellularComponent	cell surface	PTN ITGBL1 HEG1 ADAM19 ROR2 SCUBE3 LRP4 TRPM8 TNFRSF1A GPC6 LY6G5C IL6 TFPI	1.47e-04	1111	75	13	GO:0009986
GeneOntologyCellularComponent	microtubule organizing center attachment site	SYNE1 SYNE2	6.84e-04	11	75	2	GO:0034992
GeneOntologyCellularComponent	meiotic nuclear membrane microtubule tethering complex	SYNE1 SYNE2	6.84e-04	11	75	2	GO:0034993
GeneOntologyCellularComponent	nuclear membrane protein complex	SYNE1 SYNE2	6.84e-04	11	75	2	GO:0106083
GeneOntologyCellularComponent	nuclear membrane microtubule tethering complex	SYNE1 SYNE2	6.84e-04	11	75	2	GO:0106094
GeneOntologyCellularComponent	dendrite	PTPRZ1 SYNE1 ROR2 ANKS1B HRH1 LRP4 SPG11 LTBP1 KIF5A HCFC1	9.53e-04	858	75	10	GO:0030425
GeneOntologyCellularComponent	dendritic tree	PTPRZ1 SYNE1 ROR2 ANKS1B HRH1 LRP4 SPG11 LTBP1 KIF5A HCFC1	9.70e-04	860	75	10	GO:0097447
GeneOntologyCellularComponent	postsynapse	PTN DLGAP1 ATR PTPRZ1 SYNE1 ROR2 ANKS1B LRP4 KIF5A AKAP1 GABRR3	9.72e-04	1018	75	11	GO:0098794
GeneOntologyCellularComponent	postsynaptic specialization, intracellular component	DLGAP1 ANKS1B AKAP1	1.07e-03	56	75	3	GO:0099091
GeneOntologyCellularComponent	synaptic membrane	DLGAP1 SCN11A NRXN3 PTPRZ1 SYNE1 LRP4 AKAP1 GABRR3	1.14e-03	583	75	8	GO:0097060
Domain	ASX_HYDROXYL	HEG1 NRXN3 SCUBE3 LRP4 LTBP1	4.78e-05	100	74	5	PS00010
Domain	EGF-like_dom	ITGBL1 HEG1 ADAM19 NRXN3 SCUBE3 LRP4 LTBP1	5.79e-05	249	74	7	IPR000742
Domain	EGF-type_Asp/Asn_hydroxyl_site	HEG1 NRXN3 SCUBE3 LRP4 LTBP1	6.32e-05	106	74	5	IPR000152
Domain	EGF_1	ITGBL1 HEG1 ADAM19 NRXN3 SCUBE3 LRP4 LTBP1	6.73e-05	255	74	7	PS00022
Domain	EGF_2	ITGBL1 HEG1 ADAM19 NRXN3 SCUBE3 LRP4 LTBP1	8.56e-05	265	74	7	PS01186
Domain	KASH	SYNE1 SYNE2	9.24e-05	4	74	2	PF10541
Domain	KASH	SYNE1 SYNE2	9.24e-05	4	74	2	IPR012315
Domain	KASH	SYNE1 SYNE2	9.24e-05	4	74	2	PS51049
Domain	KASH	SYNE1 SYNE2	9.24e-05	4	74	2	SM01249
Domain	EGF	HEG1 NRXN3 SCUBE3 LRP4 LTBP1	1.43e-04	126	74	5	PF00008
Domain	cEGF	SCUBE3 LRP4 LTBP1	1.45e-04	26	74	3	IPR026823
Domain	cEGF	SCUBE3 LRP4 LTBP1	1.45e-04	26	74	3	PF12662
Domain	EGF_3	HEG1 ADAM19 NRXN3 SCUBE3 LRP4 LTBP1	3.38e-04	235	74	6	PS50026
Domain	EGF	ITGBL1 HEG1 NRXN3 SCUBE3 LRP4 LTBP1	3.38e-04	235	74	6	SM00181
Domain	EGF_CA	HEG1 SCUBE3 LRP4 LTBP1	3.77e-04	86	74	4	PF07645
Domain	EGF-like_CS	HEG1 ADAM19 NRXN3 SCUBE3 LRP4 LTBP1	5.88e-04	261	74	6	IPR013032
Domain	EGF_Ca-bd_CS	HEG1 SCUBE3 LRP4 LTBP1	5.96e-04	97	74	4	IPR018097
Domain	EGF_CA	HEG1 SCUBE3 LRP4 LTBP1	6.43e-04	99	74	4	PS01187
Domain	HEAT	CAND1 MROH1 ATR	9.09e-04	48	74	3	PF02985
Domain	EGF_CA	HEG1 SCUBE3 LRP4 LTBP1	1.40e-03	122	74	4	SM00179
Domain	EGF-like_Ca-bd_dom	HEG1 SCUBE3 LRP4 LTBP1	1.49e-03	124	74	4	IPR001881
Domain	HEAT	CAND1 MROH1 ATR	1.58e-03	58	74	3	IPR000357
Domain	HEAT_type_2	MROH1 ATR	2.03e-03	17	74	2	IPR021133
Domain	USP_CS	USP26 USP34 USP3	2.28e-03	66	74	3	IPR018200
Domain	Butyrophylin	TRIM43B TRIM43 RFPL2	2.70e-03	70	74	3	IPR003879
Domain	HEAT_REPEAT	CAND1 MROH1 ATR	2.70e-03	70	74	3	PS50077
Domain	USP_1	USP26 USP34 USP3	2.70e-03	70	74	3	PS00972
Domain	UCH	USP26 USP34 USP3	2.81e-03	71	74	3	PF00443
Domain	USP_2	USP26 USP34 USP3	2.81e-03	71	74	3	PS00973
Domain	USP_3	USP26 USP34 USP3	2.93e-03	72	74	3	PS50235
Domain	USP_dom	USP26 USP34 USP3	2.93e-03	72	74	3	IPR028889
Domain	Peptidase_C19_UCH	USP26 USP34 USP3	2.93e-03	72	74	3	IPR001394
Domain	Actinin_actin-bd_CS	SYNE1 SYNE2	3.71e-03	23	74	2	IPR001589
Domain	Spectrin	SYNE1 SYNE2	3.71e-03	23	74	2	PF00435
Domain	ACTININ_2	SYNE1 SYNE2	3.71e-03	23	74	2	PS00020
Domain	ACTININ_1	SYNE1 SYNE2	3.71e-03	23	74	2	PS00019
Domain	MetalloPept_cat_dom	ADAM19 MIPEP ADAMTS20	4.08e-03	81	74	3	IPR024079
Domain	-	ADAM19 MIPEP ADAMTS20	4.08e-03	81	74	3	3.40.390.10
Domain	SPRY	TRIM43B TRIM43 RFPL2	4.99e-03	87	74	3	SM00449
Domain	Spectrin_repeat	SYNE1 SYNE2	5.87e-03	29	74	2	IPR002017
Domain	SPRY	TRIM43B TRIM43 RFPL2	6.18e-03	94	74	3	PF00622
Domain	SPRY_dom	TRIM43B TRIM43 RFPL2	6.18e-03	94	74	3	IPR003877
Domain	B30.2/SPRY	TRIM43B TRIM43 RFPL2	6.37e-03	95	74	3	IPR001870
Domain	B302_SPRY	TRIM43B TRIM43 RFPL2	6.37e-03	95	74	3	PS50188
Domain	ZINC_PROTEASE	ADAM19 MIPEP ADAMTS20	6.94e-03	98	74	3	PS00142
Domain	Spectrin/alpha-actinin	SYNE1 SYNE2	7.11e-03	32	74	2	IPR018159
Domain	SPEC	SYNE1 SYNE2	7.11e-03	32	74	2	SM00150
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	TRIM43B ZC3H7A MACC1 SCN11A NRXN3 PCDHGA10 ZNF330 SYNE1 SYNE2 ANKS1B CCDC150 ANKRD30B TRIM43 SPG11 KIF5A DNAH8	7.25e-08	1442	76	16	35575683
Pubmed	Nesprins: a novel family of spectrin-repeat-containing proteins that localize to the nuclear membrane in multiple tissues.	SYNE1 SYNE2	4.71e-06	2	76	2	11792814
Pubmed	Nesprin-1 and nesprin-2 regulate endothelial cell shape and migration.	SYNE1 SYNE2	4.71e-06	2	76	2	24931616
Pubmed	Interleukin-6 Facilitates Acute Myeloid Leukemia Chemoresistance via Mitofusin 1-Mediated Mitochondrial Fusion.	IL6 MFN1	4.71e-06	2	76	2	37698549
Pubmed	Establishment of the role of IL-6 and TNF receptor 1 using gene knockout mice.	TNFRSF1A IL6	4.71e-06	2	76	2	7964164
Pubmed	Nitric oxide stimulates migration of human endothelial and prostate cancer cells through up-regulation of pleiotrophin expression and its receptor protein tyrosine phosphatase beta/zeta.	PTN PTPRZ1	4.71e-06	2	76	2	19058221
Pubmed	Differential induction of glioblastoma migration and growth by two forms of pleiotrophin.	PTN PTPRZ1	4.71e-06	2	76	2	15908427
Pubmed	Protein tyrosine phosphatase receptor type Z is inactivated by ligand-induced oligomerization.	PTN PTPRZ1	4.71e-06	2	76	2	16814777
Pubmed	Pleiotrophin enhances clonal growth and long-term expansion of human embryonic stem cells.	PTN PTPRZ1	4.71e-06	2	76	2	17823238
Pubmed	Multiple novel nesprin-1 and nesprin-2 variants act as versatile tissue-specific intracellular scaffolds.	SYNE1 SYNE2	4.71e-06	2	76	2	22768332
Pubmed	A basic peptide derived from the HARP C-terminus inhibits anchorage-independent growth of DU145 prostate cancer cells.	PTN PTPRZ1	4.71e-06	2	76	2	17727841
Pubmed	Correlational analysis for identifying genes whose regulation contributes to chronic neuropathic pain.	SCN11A TRPM8	4.71e-06	2	76	2	19228393
Pubmed	Retarded liver growth in interleukin-6-deficient and tumor necrosis factor receptor-1-deficient mice.	TNFRSF1A IL6	4.71e-06	2	76	2	11416016
Pubmed	Pleiotrophin regulates the retention and self-renewal of hematopoietic stem cells in the bone marrow vascular niche.	PTN PTPRZ1	4.71e-06	2	76	2	23084748
Pubmed	Histamine induces interleukin-6 expression in the human synovial sarcoma cell line (SW982) through the H1 receptor.	HRH1 IL6	4.71e-06	2	76	2	17122961
Pubmed	Tumour-associated macrophages secrete pleiotrophin to promote PTPRZ1 signalling in glioblastoma stem cells for tumour growth.	PTN PTPRZ1	4.71e-06	2	76	2	28569747
Pubmed	Proteomic detection of cancer in asbestosis patients using SELDI-TOF discovered serum protein biomarkers.	KIF18A KIF5A	4.71e-06	2	76	2	21231887
Pubmed	Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.	SYNE1 SYNE2	4.71e-06	2	76	2	17267447
Pubmed	Nesprins: tissue-specific expression of epsilon and other short isoforms.	SYNE1 SYNE2	4.71e-06	2	76	2	24718612
Pubmed	Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.	SYNE1 SYNE2	4.71e-06	2	76	2	24586179
Pubmed	A Pleiotrophin C-terminus peptide induces anti-cancer effects through RPTPβ/ζ.	PTN PTPRZ1	4.71e-06	2	76	2	20738847
Pubmed	Characterization of heparin affin regulatory peptide signaling in human endothelial cells.	PTN PTPRZ1	4.71e-06	2	76	2	15797857
Pubmed	Nesprin-1 and -2 are involved in the pathogenesis of Emery Dreifuss muscular dystrophy and are critical for nuclear envelope integrity.	SYNE1 SYNE2	4.71e-06	2	76	2	17761684
Pubmed	Nesprin-1-alpha2 associates with kinesin at myotube outer nuclear membranes, but is restricted to neuromuscular junction nuclei in adult muscle.	SYNE1 SYNE2	4.71e-06	2	76	2	31578382
Pubmed	Pleiotrophin mediates hematopoietic regeneration via activation of RAS.	PTN PTPRZ1	4.71e-06	2	76	2	25250571
Pubmed	Inflammatory Markers and Outcomes After Lacunar Stroke: Levels of Inflammatory Markers in Treatment of Stroke Study.	TNFRSF1A IL6	4.71e-06	2	76	2	26888535
Pubmed	Deficiency of TNFR1 protects myocardium through SOCS3 and IL-6 but not p38 MAPK or IL-1beta.	TNFRSF1A IL6	1.41e-05	3	76	2	17114246
Pubmed	Anaplastic lymphoma kinase: "Ligand Independent Activation" mediated by the PTN/RPTPβ/ζ signaling pathway.	PTN PTPRZ1	1.41e-05	3	76	2	23777859
Pubmed	The assessment of the prognostic value of tumor markers and cytokines as SCCAg, CYFRA 21.1, IL-6, VEGF and sTNF receptors in patients with squamous cell cervical cancer, particularly with early stage of the disease.	TNFRSF1A IL6	1.41e-05	3	76	2	26289850
Pubmed	The inner nuclear membrane protein Sun1 mediates the anchorage of Nesprin-2 to the nuclear envelope.	SYNE1 SYNE2	1.41e-05	3	76	2	16079285
Pubmed	Distinct role of interleukin-6 and tumor necrosis factor receptor-1 in oval cell- mediated liver regeneration and inflammation-associated hepatocarcinogenesis.	TNFRSF1A IL6	1.41e-05	3	76	2	27556180
Pubmed	Physiological role of tumor necrosis factor alpha in traumatic muscle injury.	TNFRSF1A IL6	1.41e-05	3	76	2	12207010
Pubmed	Chemotherapy-driven increases in the CDKN1A/PTN/PTPRZ1 axis promote chemoresistance by activating the NF-κB pathway in breast cancer cells.	PTN PTPRZ1	1.41e-05	3	76	2	30497491
Pubmed	IL-22 induces an acute-phase response.	TNFRSF1A IL6	1.41e-05	3	76	2	20870942
Pubmed	Tissue factor pathway inhibitor attenuates ER stress-induced inflammation in human M2-polarized macrophages.	IL6 TFPI	1.41e-05	3	76	2	28712870
Pubmed	Syne-1, a dystrophin- and Klarsicht-related protein associated with synaptic nuclei at the neuromuscular junction.	SYNE1 SYNE2	1.41e-05	3	76	2	10878022
Pubmed	Genetic analysis of immunomodulating factors in sporadic Parkinson's disease.	TNFRSF1A IL6	1.41e-05	3	76	2	11072751
Pubmed	Impaired preneoplastic changes and liver tumor formation in tumor necrosis factor receptor type 1 knockout mice.	TNFRSF1A IL6	1.41e-05	3	76	2	11120777
Pubmed	Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis.	TNFRSF1A IL6	1.41e-05	3	76	2	15558055
Pubmed	The nesprins are giant actin-binding proteins, orthologous to Drosophila melanogaster muscle protein MSP-300.	SYNE1 SYNE2	1.41e-05	3	76	2	12408964
Pubmed	Distinct functional domains in nesprin-1alpha and nesprin-2beta bind directly to emerin and both interactions are disrupted in X-linked Emery-Dreifuss muscular dystrophy.	SYNE1 SYNE2	1.41e-05	3	76	2	17462627
Pubmed	Structures of FHOD1-Nesprin1/2 complexes reveal alternate binding modes for the FH3 domain of formins.	SYNE1 SYNE2	1.41e-05	3	76	2	33472039
Pubmed	Anaplastic lymphoma kinase is activated through the pleiotrophin/receptor protein-tyrosine phosphatase beta/zeta signaling pathway: an alternative mechanism of receptor tyrosine kinase activation.	PTN PTPRZ1	1.41e-05	3	76	2	17681947
Pubmed	Nesprins anchor kinesin-1 motors to the nucleus to drive nuclear distribution in muscle cells.	SYNE1 SYNE2	1.41e-05	3	76	2	25516977
Pubmed	Impaired glucose tolerance is associated with increased serum concentrations of interleukin 6 and co-regulated acute-phase proteins but not TNF-alpha or its receptors.	TNFRSF1A IL6	1.41e-05	3	76	2	12107724
Pubmed	Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.	GREM2 PTN CRISPLD2 ADAM19 LTBP1	1.44e-05	140	76	5	26930384
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP34 DLGAP1 EXOSC9 ADAM19 CAND1 ZNF334 SYNE1 ZNF451 ANKS1B LRP4 KIF5A PCM1	2.15e-05	1285	76	12	35914814
Pubmed	Pleiotrophin signals increased tyrosine phosphorylation of beta beta-catenin through inactivation of the intrinsic catalytic activity of the receptor-type protein tyrosine phosphatase beta/zeta.	PTN PTPRZ1	2.82e-05	4	76	2	10706604
Pubmed	Constitutive intestinal NF-κB does not trigger destructive inflammation unless accompanied by MAPK activation.	TNFRSF1A IL6	2.82e-05	4	76	2	21825016
Pubmed	Acute pericardial effusion representing the TNF-α-mediated severe inflammation but not the coronary artery outcome of Kawasaki disease.	TNFRSF1A IL6	2.82e-05	4	76	2	25351965
Pubmed	SUN1 interacts with nuclear lamin A and cytoplasmic nesprins to provide a physical connection between the nuclear lamina and the cytoskeleton.	SYNE1 SYNE2	2.82e-05	4	76	2	16648470
Pubmed	Role of Chondroitin Sulfate (CS) Modification in the Regulation of Protein-tyrosine Phosphatase Receptor Type Z (PTPRZ) Activity: PLEIOTROPHIN-PTPRZ-A SIGNALING IS INVOLVED IN OLIGODENDROCYTE DIFFERENTIATION.	PTN PTPRZ1	2.82e-05	4	76	2	27445335
Pubmed	Multilocus interactions at maternal tumor necrosis factor-alpha, tumor necrosis factor receptors, interleukin-6 and interleukin-6 receptor genes predict spontaneous preterm labor in European-American women.	TNFRSF1A IL6	2.82e-05	4	76	2	16731080
Pubmed	Inflammation marker and risk of pancreatic cancer: a nested case-control study within the EPIC cohort.	TNFRSF1A IL6	2.82e-05	4	76	2	22617158
Pubmed	Exercise normalises overexpression of TNF-alpha in knockout mice.	TNFRSF1A IL6	2.82e-05	4	76	2	15358232
Pubmed	Role of heparin binding growth factors in nigrostriatal dopamine system development and Parkinson's disease.	PTN PTPRZ1	2.82e-05	4	76	2	17368428
Pubmed	C-Reactive Protein, Interleukin-6, Trimethylamine-N-Oxide, Syndecan-1, Nitric Oxide, and Tumor Necrosis Factor Receptor-1 in Heart Failure with Preserved Versus Reduced Ejection Fraction: a Meta-Analysis.	TNFRSF1A IL6	2.82e-05	4	76	2	36479675
Pubmed	Outer nuclear membrane protein Kuduk modulates the LINC complex and nuclear envelope architecture.	SYNE1 SYNE2	2.82e-05	4	76	2	28716842
Pubmed	Hereditary spastic paraplegia in Greece: characterisation of a previously unexplored population using next-generation sequencing.	SPG11 KIF5A	2.82e-05	4	76	2	26374131
Pubmed	cAMP-dependent protein kinase A (PKA) signaling induces TNFR1 exosome-like vesicle release via anchoring of PKA regulatory subunit RIIbeta to BIG2.	TNFRSF1A AKAP1	2.82e-05	4	76	2	18625701
Pubmed	The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice.	PTN PTPRZ1	2.82e-05	4	76	2	30667096
Pubmed	Role of IL-6 and TNF in thermoregulation and survival during sepsis in mice.	TNFRSF1A IL6	2.82e-05	4	76	2	9688988
Pubmed	LINC complexes mediate the positioning of cone photoreceptor nuclei in mouse retina.	SYNE1 SYNE2	2.82e-05	4	76	2	23071752
Pubmed	Nesprins, but not sun proteins, switch isoforms at the nuclear envelope during muscle development.	SYNE1 SYNE2	2.82e-05	4	76	2	20108321
Pubmed	Mechanisms of the hepatic acute-phase response during bacterial pneumonia.	TNFRSF1A IL6	2.82e-05	4	76	2	19289507
Pubmed	Elevated urinary sVCAM-1, IL6, sIL6R and TNFR1 concentrations indicate acute kidney transplant rejection in the first 2 weeks after transplantation.	TNFRSF1A IL6	2.82e-05	4	76	2	22209080
Pubmed	Nesprin-2 interacts with meckelin and mediates ciliogenesis via remodelling of the actin cytoskeleton.	SYNE1 SYNE2	2.82e-05	4	76	2	19596800
Pubmed	Mammalian Target of Rapamycin Inhibition in Trypanosoma cruzi-Infected Macrophages Leads to an Intracellular Profile That Is Detrimental for Infection.	TNFRSF1A IL6	2.82e-05	4	76	2	29515594
Pubmed	Role of FAN in tumor necrosis factor-alpha and lipopolysaccharide-induced interleukin-6 secretion and lethality in D-galactosamine-sensitized mice.	TNFRSF1A IL6	2.82e-05	4	76	2	14985352
Pubmed	Insights from knock-out models concerning postischemic release of TNFalpha from isolated mouse hearts.	TNFRSF1A IL6	4.69e-05	5	76	2	17101148
Pubmed	Externalized decondensed neutrophil chromatin occludes pancreatic ducts and drives pancreatitis.	TNFRSF1A IL6	4.69e-05	5	76	2	26964500
Pubmed	LINC complexes form by binding of three KASH peptides to domain interfaces of trimeric SUN proteins.	SYNE1 SYNE2	4.69e-05	5	76	2	22632968
Pubmed	High affinity binding and overlapping localization of neurocan and phosphacan/protein-tyrosine phosphatase-zeta/beta with tenascin-R, amphoterin, and the heparin-binding growth-associated molecule.	PTN PTPRZ1	4.69e-05	5	76	2	9507007
Pubmed	VEGF receptor signaling links inflammation and tumorigenesis in colitis-associated cancer.	TNFRSF1A IL6	4.69e-05	5	76	2	21098094
Pubmed	Racial disparity in maternal-fetal genetic epistasis in spontaneous preterm birth.	TNFRSF1A IL6	4.69e-05	5	76	2	18538149
Pubmed	Nuclear factor-κB1 controls the functional maturation of dendritic cells and prevents the activation of autoreactive T cells.	TNFRSF1A IL6	4.69e-05	5	76	2	22081022
Pubmed	Inhibition of the cytokine response does not protect against lethal H5N1 influenza infection.	TNFRSF1A IL6	4.69e-05	5	76	2	17640882
Pubmed	Serum TNF-α, sTNFR1, IL-6, IL-8 and IL-10 levels in Weil's syndrome.	TNFRSF1A IL6	4.69e-05	5	76	2	21316985
Pubmed	Proinflammatory cytokines and their membrane-bound receptors are altered in the lymphocytes of schizophrenia patients.	TNFRSF1A IL6	4.69e-05	5	76	2	25749018
Pubmed	Agrin-Lrp4-Ror2 signaling regulates adult hippocampal neurogenesis in mice.	ROR2 LRP4	4.69e-05	5	76	2	31268420
Pubmed	Cyclin-dependent kinase 5 mediates pleiotrophin-induced endothelial cell migration.	PTN PTPRZ1	4.69e-05	5	76	2	29651006
Pubmed	Structural requirements for the assembly of LINC complexes and their function in cellular mechanical stiffness.	SYNE1 SYNE2	4.69e-05	5	76	2	18396275
Pubmed	IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system.	TNFRSF1A IL6	4.69e-05	5	76	2	15664785
Pubmed	A mouse model of lethal synergism between influenza virus and Haemophilus influenzae.	TNFRSF1A IL6	4.69e-05	5	76	2	20042666
Pubmed	The importance of IL-1 beta and TNF-alpha, and the noninvolvement of IL-6, in the development of monoclonal antibody-induced arthritis.	TNFRSF1A IL6	4.69e-05	5	76	2	12133972
Pubmed	Involvement of the Hsp70/TLR4/IL-6 and TNF-α pathways in delayed-onset muscle soreness.	TNFRSF1A IL6	4.69e-05	5	76	2	32173863
Pubmed	DNA Repair Network Analysis Reveals Shieldin as a Key Regulator of NHEJ and PARP Inhibitor Sensitivity.	USP34 KIF18A ATR ATAD5 ZNF451 CENPI USP3	6.12e-05	453	76	7	29656893
Pubmed	Inflammatory pathogenesis of snake venom metalloproteinase-induced skin necrosis.	TNFRSF1A IL6	7.03e-05	6	76	2	14635056
Pubmed	[Combinations of cytokine gene network polymorphic markers as potential predictors of myocardial infarction].	TNFRSF1A IL6	7.03e-05	6	76	2	25735143
Pubmed	Critical roles for interleukin 1 and tumor necrosis factor alpha in antibody-induced arthritis.	TNFRSF1A IL6	7.03e-05	6	76	2	12093872
Pubmed	An animal model of oxaliplatin-induced cold allodynia reveals a crucial role for Nav1.6 in peripheral pain pathways.	SCN11A TRPM8	7.03e-05	6	76	2	23711479
Pubmed	Structural Analysis of Different LINC Complexes Reveals Distinct Binding Modes.	SYNE1 SYNE2	7.03e-05	6	76	2	33058875
Pubmed	TorsinA binds the KASH domain of nesprins and participates in linkage between nuclear envelope and cytoskeleton.	SYNE1 SYNE2	7.03e-05	6	76	2	18827015
Pubmed	Pleiotrophin disrupts calcium-dependent homophilic cell-cell adhesion and initiates an epithelial-mesenchymal transition.	PTN PTPRZ1	7.03e-05	6	76	2	17098867
Pubmed	Integrin alpha(v)beta(3) is a pleiotrophin receptor required for pleiotrophin-induced endothelial cell migration through receptor protein tyrosine phosphatase beta/zeta.	PTN PTPRZ1	7.03e-05	6	76	2	19141530
Pubmed	IL-6 protects against hyperoxia-induced mitochondrial damage via Bcl-2-induced Bak interactions with mitofusins.	IL6 MFN1	7.03e-05	6	76	2	19168699
Pubmed	Receptor protein tyrosine phosphatase beta/zeta is a functional binding partner for vascular endothelial growth factor.	PTN PTPRZ1	7.03e-05	6	76	2	25644401
Pubmed	TAM receptors affect adult brain neurogenesis by negative regulation of microglial cell activation.	TNFRSF1A IL6	7.03e-05	6	76	2	24244024
Pubmed	CpG DNA-mediated induction of acute liver injury in D-galactosamine-sensitized mice: the mitochondrial apoptotic pathway-dependent death of hepatocytes.	TNFRSF1A IL6	7.03e-05	6	76	2	16554296
Pubmed	A human MAP kinase interactome.	ZC3H7A DLGAP1 EXOSC9 SYNE1 ZNF451 KIF5A NUP153	9.49e-05	486	76	7	20936779
GeneFamily	Spectrin repeat containing nuclear envelope family	SYNE1 SYNE2	5.43e-05	4	55	2	1252
GeneFamily	Ubiquitin specific peptidases	USP26 USP34 USP3	6.59e-04	56	55	3	366
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#1_top-relative-expression-ranked_1000	PTPRZ1 ROR2 ADAMTS20 BAMBI LTBP1	5.48e-05	120	72	5	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k1
CoexpressionAtlas	AravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2	GREM2 CRISPLD2 ITGBL1 TEKT2 HEG1 HOXD10 SCUBE3 HRH1 ADAMTS20 BAMBI GPC6 IL6	7.81e-05	951	72	12	Arv_EB-LF_2500_K2
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_1000	USP26 KIF18A ADAM19 ATR ZNF451 CENPI CCDC150 NR6A1 AKAP1 DNAH8 HCFC1	9.57e-05	822	72	11	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5	KIF18A HEG1 ATAD5 PTPRZ1 SYNE2 MIPEP SCUBE3 ADAMTS20 ZDBF2 PCM1 MFN1	1.05e-04	831	72	11	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_200	USP26 ATR CCDC150 NR6A1 DNAH8	1.26e-04	143	72	5	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_200
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k-means-cluster#1_top-relative-expression-ranked_1000	USP34 ZC3H7A CAND1 NRXN3 ATAD5 ADAMTS20 BAMBI	1.80e-04	349	72	7	DevelopingLowerUrinaryTract_e14.5_ bladder_emap-6668_k1_1000
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1	EPHX2 KIF18A HEG1 ZNF334 ATAD5 PTPRZ1 SYNE2 ZDBF2 NR6A1 USP3 TM4SF20 PCM1	2.16e-04	1060	72	12	facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlas	ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000_k-means-cluster#5	GREM2 TEKT2 ADAM19 ROR2 ANKS1B BAMBI GPC6 RFPL2	2.17e-04	480	72	8	ratio_MESO_vs_SC_1000_K5
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_MedNas_2500	EPHX2 KIF18A HEG1 NRXN3 ZNF334 ATAD5 PTPRZ1 SYNE2 ANKS1B ZDBF2 NR6A1 USP3 TM4SF20 PCM1	2.46e-04	1414	72	14	facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlas	kidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000	GREM2 CRISPLD2 ITGBL1 TEKT2 PTPRZ1 SYNE2 TFPI	2.53e-04	369	72	7	gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlas	DevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000	CRISPLD2 KIF18A ITGBL1 CAND1 SYNE1 ADAMTS20 CZIB BAMBI LTBP1 AKAP1	2.66e-04	772	72	10	gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlas	ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#1	GREM2 HEG1 ADAM19 ROR2 ANKS1B BAMBI RFPL2	2.74e-04	374	72	7	ratio_DE_vs_SC_500_K1
CoexpressionAtlas	kidney_adult_RenalCapsule_top-relative-expression-ranked_1000	GREM2 CRISPLD2 ZC3H7A ITGBL1 TEKT2 HEG1 PTPRZ1 SYNE2 GPC6 TFPI	2.83e-04	778	72	10	gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_500	USP26 KIF18A ATR CENPI CCDC150 NR6A1 DNAH8	3.26e-04	385	72	7	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_500
CoexpressionAtlas	facebase_RNAseq_e10.5_Emin_LatNas_2500	KIF18A EXOSC9 HEG1 NRXN3 ATR ZNF334 ATAD5 PTPRZ1 SYNE2 CENPI ANKS1B ZDBF2 USP3 PCM1	3.38e-04	1459	72	14	facebase_RNAseq_e10.5_Emin_LatNas_2500
CoexpressionAtlas	DevelopingGonad_e12.5_ovary_emap-28876_k-means-cluster#3_top-relative-expression-ranked_1000	PTN HEG1 ZNF451 SYNE2 GPC6 TFPI	3.55e-04	277	72	6	gudmap_developingGonad_e12.5_ovary_k3_1000
CoexpressionAtlas	dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k-means-cluster#4_top-relative-expression-ranked_1000	STK32A HOXD10 PTPRZ1 ZMAT4 ZDBF2 KIF5A	3.62e-04	278	72	6	gudmap_dev lower uro neuro_e15.5_BladdPelvicGanglion_Sox10_k4_1000
CoexpressionAtlas	dev gonad_e13.5_F_MeioticGermCell_Oct_top-relative-expression-ranked_1000	USP26 KIF18A ATR ZNF451 CENPI CCDC150 NR6A1 DNAH8 HCFC1 ZMYM6	4.28e-04	820	72	10	gudmap_dev gonad_e13.5_F_MeioticGermCell_Oct_1000
CoexpressionAtlas	ratio_induced-Mesoderm_vs_StemCell_top-relative-expression-ranked_1000	GREM2 TEKT2 ADAM19 ROR2 YPEL5 ANKS1B BAMBI LTBP1 GPC6 RFPL2 TFPI	4.45e-04	982	72	11	PCBC_ratio_MESO-5_vs_SC_1000
CoexpressionAtlas	dev gonad_e12.5_F_GermCellOvary_Oct_top-relative-expression-ranked_500	USP26 KIF18A ATR ZNF451 CENPI NR6A1 DNAH8	4.49e-04	406	72	7	gudmap_dev gonad_e12.5_F_GermCellOvary_Oct_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_top-relative-expression-ranked_1000	GREM2 USP34 TEKT2 NRXN3 PTPRZ1 ROR2 ADAMTS20 ZMAT4 KIF5A PCM1	4.58e-04	827	72	10	gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_1000
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3	KIF18A ATAD5 SYNE2 ZDBF2 PCM1	4.91e-04	192	72	5	Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlas	ratio_induced-DefinitiveEndoderm_vs_StemCell_top-relative-expression-ranked_500_k-means-cluster#5	GREM2 ADAM19 ROR2 ANKS1B BAMBI RFPL2	5.13e-04	297	72	6	ratio_DE_vs_SC_500_K5
CoexpressionAtlas	MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst-Confounder_removed-fold2.0_adjp0.05	KIF18A PTPRZ1 CCDC150 LRP4 BAMBI ZDBF2 LTBP1	5.34e-04	418	72	7	PCBC_ratio_MESO-5 amniotic fluid MSC_vs_MESO-5 blastocyst_cfr-2X-p05
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW23-Macroglial-Astrocyte\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	PTN PTPRZ1 LRP4 BAMBI LTBP1 GPC6 TFPI	5.21e-08	200	76	7	4fe3b2d80c567c18621bff3341f9a73578c81621
ToppCell	droplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A EPHX2 DLGAP1 TEKT2 PTPRZ1	6.12e-07	178	76	6	3e8aacb27ed1a3c3978e21dddddd0828f8000692
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GREM2 CRISPLD2 ITGBL1 LRP4 LTBP1 GPC6	6.75e-07	181	76	6	b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A CRISPLD2 PTPRZ1 LRP4 BAMBI	6.97e-07	182	76	6	8a8b08ac4bb3cba3541dbe234e088703842285b9
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A CRISPLD2 PTPRZ1 LRP4 BAMBI	6.97e-07	182	76	6	a05e5978ef5f7fac7eeb2ba1c0103ea90d5e9136
ToppCell	Primary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A CRISPLD2 PTPRZ1 LRP4 BAMBI	6.97e-07	182	76	6	831b5ce46b41efe01c4db6016c2f43148611373d
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A CRISPLD2 PTPRZ1 LRP4 BAMBI	6.97e-07	182	76	6	e36766309c4d96a90d213ce37d3acef1029a3fdc
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B ADAMTS20	7.20e-07	183	76	6	2cf36ad89584eb9f8b04de52a1b511b7f3527884
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B ADAMTS20	7.20e-07	183	76	6	98fee6838acfaee5e2e449ba088764ec06b8bc57
ToppCell	droplet-Limb_Muscle-nan-3m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B ADAMTS20	7.43e-07	184	76	6	da8d6e7944eb35e6cbea2feb7cbc2894787d723f
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B ZMAT4	7.67e-07	185	76	6	11c147f3f5570c4761d2bcff3bad28146b4a5861
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A CRISPLD2 PTPRZ1 LRP4 BAMBI	7.67e-07	185	76	6	2e1766f1a972fecd670daaaf7eb2d3a404f121e7
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Oligo-OPC\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A CRISPLD2 PTPRZ1 LRP4 BAMBI	7.67e-07	185	76	6	7aaa8335b40927e3e8fdcede807cd521fc213a0d
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 SYNE1 SYNE2 HRH1 GPC6 TFPI	7.92e-07	186	76	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 MACC1 SYNE2 HRH1 NR6A1 GPC6	7.92e-07	186	76	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	-Unknown-Endothelial-Myofibroblast\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GREM2 ROR2 ZDBF2 LTBP1 GPC6 MFN1	8.43e-07	188	76	6	6468fa95ad0395395301115286f2d8c0df5d3882
ToppCell	-Unknown-Endothelial\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GREM2 ROR2 ZDBF2 LTBP1 GPC6 MFN1	8.43e-07	188	76	6	7a81ac5c79c3eb26639b52d2b9fd5e7ef9798fd6
ToppCell	-Unknown\| / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GREM2 ROR2 ZDBF2 LTBP1 GPC6 MFN1	8.43e-07	188	76	6	9cb718bfe1358c6fd842f096e228eb0abb9aefc6
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B ZMAT4	8.43e-07	188	76	6	c2101ded71fb16b8ddbc1f883911b1ed2a533ffc
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B ZMAT4	8.43e-07	188	76	6	3b8b9161f0fdcbde302ce5b4c0bc874628211109
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GREM2 CRISPLD2 DLGAP1 ADAM19 LTBP1 AKAP1	8.43e-07	188	76	6	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRISPLD2 DLGAP1 HEG1 ROR2 LTBP1 GPC6	9.82e-07	193	76	6	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GREM2 PTN CRISPLD2 ITGBL1 ROR2 LTBP1	1.01e-06	194	76	6	91205b22650e7ecdb72bb59348ce2530b76c532c
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GREM2 PTN CRISPLD2 ITGBL1 ROR2 LTBP1	1.01e-06	194	76	6	6e12a7da35be4c0ecf998ef94b8989b89d74b200
ToppCell	3'-Broncho-tracheal-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GREM2 PTN CRISPLD2 ITGBL1 ROR2 LTBP1	1.01e-06	194	76	6	c52f10140c66e8c0566421c3d535d5d92bf595e1
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTN CRISPLD2 LRP4 BAMBI LTBP1 TFPI	1.11e-06	197	76	6	ea746772adb9df4ddb0508d4ef35f2027bf09c35
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DLGAP1 MACC1 SYNE2 HRH1 NR6A1 TFPI	1.11e-06	197	76	6	7e93a97b5ac5ae2f77a4b3141082a1463fed00dd
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 ITGBL1 SYNE1 ROR2 LTBP1 TFPI	1.11e-06	197	76	6	9b480f9c799a244bfee64487abd8a1bf07c9a3a2
ToppCell	Non-neuronal-Dividing-Radial_Glia-vRG-20\|World / Primary Cells by Cluster	PTN HEG1 PTPRZ1 SYNE2 LTBP1 TFPI	1.14e-06	198	76	6	bce0bc1e3f2257e0f42a1fa6e5b57cf71e4514ba
ToppCell	Tracheal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	CRISPLD2 ITGBL1 ROR2 ANKRD30B LTBP1 KIF5A	1.14e-06	198	76	6	08d393853e195a7eacace454153e425a273e2d23
ToppCell	medial-2-mesenchymal-Myofibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GREM2 CRISPLD2 ITGBL1 ROR2 LTBP1 KIF5A	1.17e-06	199	76	6	95aae608fa35a9c82b12c6f18937ce636750ca44
ToppCell	medial-mesenchymal-Myofibroblast\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GREM2 CRISPLD2 ITGBL1 ROR2 LTBP1 KIF5A	1.17e-06	199	76	6	e25acdb5809aaff631cb06dbe4c7e59549a0bdb9
ToppCell	medial-mesenchymal-Myofibroblast-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GREM2 CRISPLD2 ITGBL1 ROR2 LTBP1 KIF5A	1.17e-06	199	76	6	9ebf4822ff9fa08574edec5dbf4f2a1488f34b1d
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_D\|E18.5-samps / Age Group, Lineage, Cell class and subclass	EPHX2 TEKT2 PTPRZ1 LTBP1 GPC6	5.69e-06	149	76	5	dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 NRXN3 PTPRZ1 ZNF330 KIF5A	9.62e-06	166	76	5	f742d15b02a6f651bbd00f53e3d871f40d05a03d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 NRXN3 PTPRZ1 ZNF330 KIF5A	9.62e-06	166	76	5	0f013bb5fdb72e88c2fc73d60cd01551a2db6341
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell-Schwann_Cell_/_Neural\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 NRXN3 PTPRZ1 ZNF330 KIF5A	9.62e-06	166	76	5	e941df9a1091164edde3def8fc7d410186b2bd88
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Neural-neural_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAM19 NRXN3 PTPRZ1 ZNF330 KIF5A	9.62e-06	166	76	5	aeda46bea5d8463c24a83b98b9ed92d962d733e5
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	PTN DLGAP1 SCN11A PTPRZ1 SCUBE3	1.11e-05	171	76	5	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 NRXN3 ANKS1B KIF5A USP3	1.24e-05	175	76	5	65571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 NRXN3 LTBP1 GPC6 DNAH8	1.24e-05	175	76	5	316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CRISPLD2 NRXN3 LTBP1 GPC6 DNAH8	1.24e-05	175	76	5	a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CRISPLD2 DLGAP1 ADAM19 ZNF334 LTBP1	1.31e-05	177	76	5	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	Children_(3_yrs)-Mesenchymal-airway_smooth_muscle_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	GREM2 CRISPLD2 ITGBL1 ROR2 LTBP1	1.31e-05	177	76	5	b59967219f7d874805768e247c0eb2bc4d4420c8
ToppCell	droplet-Limb_Muscle-nan-21m-Endothelial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DLGAP1 TEKT2 ROR2 NR6A1 AKAP1	1.31e-05	177	76	5	291231b1520c135e92739e201495fe1935efa927
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	GREM2 CRISPLD2 ITGBL1 HEG1 SYNE1	1.35e-05	178	76	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.35e-05	178	76	5	ef490b45901b2e6dedb519540fa3ae4e4db3a9ba
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A TEKT2 PTPRZ1 BAMBI TM4SF20	1.39e-05	179	76	5	7c8a2fa1326c73dc9e774df645b572864fd97133
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN CRISPLD2 USP26 ITGBL1 IL6	1.39e-05	179	76	5	6f51a4580c06fc55cc764052c9b26f7c55660282
ToppCell	COVID-19-kidney-vSMC/Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CRISPLD2 NRXN3 HOXD10 LTBP1 GPC6	1.39e-05	179	76	5	111b1084f73306bdeffaaf240e7dbb4f5bf33de1
ToppCell	LPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A NRXN3 SYNE2 GPC6 AKAP1	1.39e-05	179	76	5	fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN CRISPLD2 USP26 ITGBL1 IL6	1.39e-05	179	76	5	f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCell	droplet-Bladder-nan-24m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A EPHX2 DLGAP1 HOXD10 ANKS1B	1.39e-05	179	76	5	3d6bb3cfe89d60f2f00aead9341f9967e5313763
ToppCell	facs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN CRISPLD2 USP26 ITGBL1 IL6	1.39e-05	179	76	5	a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	GREM2 DLGAP1 MACC1 NRXN3 GPC6	1.39e-05	179	76	5	04ce3673e46606f63d9c87bcba3a64c96817d812
ToppCell	LA-01._Fibroblast_I\|LA / Chamber and Cluster_Paper	PTN CRISPLD2 ITGBL1 GPC6 TFPI	1.39e-05	179	76	5	dcb6ec9ae72b13fe388b72dace2815293fafe8ee
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A MACC1 NRXN3 GPC6 AKAP1	1.42e-05	180	76	5	b798a3fa2dd15b68aa4267f665559527043dcc07
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STK32A TEKT2 PTPRZ1 BAMBI TM4SF20	1.42e-05	180	76	5	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTN STK32A NRXN3 PTPRZ1 ANKS1B	1.46e-05	181	76	5	3aa81ac64d0cc9a74fbfa71e2176740548e7cd06
ToppCell	5'-Adult-Appendix-Neuronal-Glial_mature-Adult_Glia\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTN STK32A NRXN3 PTPRZ1 ANKS1B	1.46e-05	181	76	5	997ba1be2824b00d684f2163d0114656ed11fa53
ToppCell	5'-Adult-Appendix-Neuronal\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PTN STK32A NRXN3 PTPRZ1 ANKS1B	1.46e-05	181	76	5	e6b7e8dd5c13cc10ba22f2f5a8c669486f934bdc
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.50e-05	182	76	5	d568a8aec7e27ce632e248baea2ccd0e8dd255ac
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.50e-05	182	76	5	a512863304fad80acaab60a8c6107eb7c9cbac99
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CRISPLD2 ROR2 HRH1 LRP4 LTBP1	1.50e-05	182	76	5	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.50e-05	182	76	5	e89cc30db8e5c77a8bbddd1d5a4b5af09f1ccd67
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A PTPRZ1 LRP4 BAMBI	1.50e-05	182	76	5	3cc61f5f7ad4a81eba3daf65e122880b5af3adc0
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.50e-05	182	76	5	82ca6d5ed48b4c487ce00b9309255abb8f20b61d
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A PTPRZ1 LRP4 BAMBI	1.50e-05	182	76	5	5d909e4b5f662905bf1be9c686bbddc3e87d2be9
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A MACC1 NRXN3 GPC6 AKAP1	1.50e-05	182	76	5	17ed11a7ea366dd3106400511d5e628d3f1a9c3e
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ROR2 ANKS1B LRP4 LTBP1 GPC6	1.54e-05	183	76	5	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 ITGBL1 LTBP1 GPC6 IL6	1.54e-05	183	76	5	63294d66e3ccf152ffe5d1237106764c14390b62
ToppCell	5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GREM2 CRISPLD2 ITGBL1 ROR2 LTBP1	1.54e-05	183	76	5	bc7dd6a40ec9c773d005c1a46f305d40cdd0a326
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CRISPLD2 ITGBL1 LTBP1 GPC6 IL6	1.54e-05	183	76	5	7e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 KIF5A	1.54e-05	183	76	5	8330c39184ce076e1f95fd3725b68af551d89db0
ToppCell	P03-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTN STK32A DLGAP1 PTPRZ1 KIF5A	1.58e-05	184	76	5	8880ff36c243cc60a524d74934d000aef26a70ac
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-AT2_Progenitor\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A MACC1 NRXN3 GPC6 AKAP1	1.58e-05	184	76	5	d0c212a8fbaad24597a84018442b25c61c17ea58
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A MACC1 NRXN3 GPC6 AKAP1	1.58e-05	184	76	5	ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.62e-05	185	76	5	3d1353dbcb60e2531ef67e1bd218b7bc4d7c7c9b
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A PTPRZ1 LRP4 BAMBI	1.62e-05	185	76	5	efc5d564f8793c751ba640aef60f761e4b081d3f
ToppCell	droplet-Limb_Muscle-nan-21m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.62e-05	185	76	5	995a8ddc3fd8e6879d8b5de8cbdefe232d34833b
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CRISPLD2 ITGBL1 ROR2 LTBP1 GPC6	1.62e-05	185	76	5	87c416d14ca6255bee39b16e7571553e36ee3069
ToppCell	primary_auditory_cortex_(A1C)-Non-neuronal-Macroglial-Oligo-OPC\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A PTPRZ1 LRP4 BAMBI	1.62e-05	185	76	5	fba2dc46cd98ab9c78e788959c2121aa10d148b2
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ADAMTS20	1.67e-05	186	76	5	adba5647a2feaba8e361dc1020d2f2dc4ce36b16
ToppCell	droplet-Limb_Muscle-MUSCLE-30m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.67e-05	186	76	5	d8d559daff4aeef334d403fde4e3ee2e4a6086d0
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DLGAP1 MACC1 NRXN3 NR6A1 GPC6	1.67e-05	186	76	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ANKS1B	1.67e-05	186	76	5	ea936e66ae4b7b40564711fad60ac0137327995f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A MACC1 NRXN3 GPC6 AKAP1	1.67e-05	186	76	5	e83718fabb057100835d3357df407f283d23fe16
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTN KIF18A ATAD5 ROR2 CENPI	1.71e-05	187	76	5	e41e39fd3791acf8ae5376cc5061e196d96868ae
ToppCell	LA-01._Fibroblast_I\|World / Chamber and Cluster_Paper	CRISPLD2 ITGBL1 ANKS1B GPC6 TFPI	1.71e-05	187	76	5	4ea486991f66c29728d127171a07b81404ec0b78
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A PTPRZ1 LRP4 BAMBI	1.71e-05	187	76	5	daff7ccd3f1924cf2b34d3aca3eccde245aaf371
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Cycling_Myofibroblast\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PTN KIF18A ATAD5 ROR2 CENPI	1.71e-05	187	76	5	cefa211ef224e803ea9467882e2ca74d0b1492f1
ToppCell	COVID-19-Fibroblasts-Airway_smooth_muscle\|COVID-19 / group, cell type (main and fine annotations)	CRISPLD2 ITGBL1 ROR2 LTBP1 GPC6	1.71e-05	187	76	5	464a0c3b92b778911b5f9cd73642e09e3472063a
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D175\|Adult / Lineage, Cell type, age group and donor	CRISPLD2 DLGAP1 ROR2 GPC6 IL6	1.71e-05	187	76	5	e15d2967aac248da3517bc2c7d1beaa1d5a0aa7f
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ADAMTS20	1.71e-05	187	76	5	a0bd2b0ec9e73521c245037b1dd51ff8cf24cbf5
ToppCell	droplet-Limb_Muscle-nan-24m-Macroglial-Schwann_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTN STK32A DLGAP1 PTPRZ1 ADAMTS20	1.71e-05	187	76	5	f2af79a20438108c814a73f9e24cd986d537237f
ToppCell	Primary_Visual_cortex_(V1C)-Non-neuronal-Macroglial-Oligo-OPC-OPC_L1-6_MYT1\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTN STK32A PTPRZ1 LRP4 BAMBI	1.71e-05	187	76	5	5b7a1edee602e55d3400dc17dbb6b8aaa26defc0
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STK32A MACC1 NRXN3 GPC6 AKAP1	1.75e-05	188	76	5	4bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	GREM2 CRISPLD2 ADAM19 HRH1 LTBP1	1.75e-05	188	76	5	4d1e5f85342ae550086609d7680e32730b78b5d2
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GREM2 CRISPLD2 NRXN3 LTBP1 SLC35F4	1.75e-05	188	76	5	879de94924de978478696fc7838e05a4d795b905
ToppCell	5'-Adult-SmallIntestine-Mesenchymal-myocytic\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	GREM2 CRISPLD2 NRXN3 LTBP1 SLC35F4	1.80e-05	189	76	5	ab7ece0a517499b70b7754720d3e434765363af6
Drug	aspirin, USP; Up 200; 100uM; MCF7; HT_HG-U133A	PTN EPHX2 ITGBL1 SCN11A PCDHGA10 ADAMTS20 NR6A1	3.68e-06	195	75	7	5564_UP
Disease	ovarian hyperstimulation syndrome (is_marker_for)	IL6 TFPI	1.76e-05	3	72	2	DOID:5425 (is_marker_for)
Disease	Autosomal dominant Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	3.51e-05	4	72	2	cv:CN293514
Disease	Autosomal Recessive Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	5.84e-05	5	72	2	C1450051
Disease	disseminated intravascular coagulation (biomarker_via_orthology)	IL6 TFPI	5.84e-05	5	72	2	DOID:11247 (biomarker_via_orthology)
Disease	Autosomal Dominant Emery-Dreifuss Muscular Dystrophy (disorder)	SYNE1 SYNE2	5.84e-05	5	72	2	C0410190
Disease	Emery-Dreifuss muscular dystrophy	SYNE1 SYNE2	8.75e-05	6	72	2	cv:C0410189
Disease	Muscular Dystrophy, Emery-Dreifuss	SYNE1 SYNE2	8.75e-05	6	72	2	C0410189
Disease	HIV-1 infection	USP26 MACC1 USP3 SLC35F4	9.90e-05	98	72	4	EFO_0000180
Disease	electrodermal activity measurement, skin conductance response amplitude	NRXN3 ANKS1B	1.22e-04	7	72	2	EFO_0006866, EFO_0006868
Disease	X-Linked Emery-Dreifuss Muscular Dystrophy	SYNE1 SYNE2	1.22e-04	7	72	2	C0751337
Disease	Congestive heart failure	EPHX2 BAMBI TNFRSF1A IL6	1.55e-04	110	72	4	C0018802
Disease	Heart failure	EPHX2 BAMBI TNFRSF1A IL6	1.55e-04	110	72	4	C0018801
Disease	Left-Sided Heart Failure	EPHX2 BAMBI TNFRSF1A IL6	1.55e-04	110	72	4	C0023212
Disease	Heart Failure, Right-Sided	EPHX2 BAMBI TNFRSF1A IL6	1.55e-04	110	72	4	C0235527
Disease	Heart Decompensation	EPHX2 BAMBI TNFRSF1A IL6	1.55e-04	110	72	4	C1961112
Disease	Myocardial Failure	EPHX2 BAMBI TNFRSF1A IL6	1.55e-04	110	72	4	C1959583
Disease	visceral adipose tissue measurement	ARMH2 KIF18A SCN11A HEG1 NRXN3 ROR2 GPC6	1.73e-04	481	72	7	EFO_0004765
Disease	disseminated intravascular coagulation (is_marker_for)	IL6 TFPI	2.61e-04	10	72	2	DOID:11247 (is_marker_for)
Disease	Pancreatic Ductal Adenocarcinoma	ADAM19 ABCA12	3.18e-04	11	72	2	C1335302
Disease	Emery-Dreifuss muscular dystrophy (implicated_via_orthology)	SYNE1 SYNE2	3.81e-04	12	72	2	DOID:11726 (implicated_via_orthology)
Disease	Cachexia	TNFRSF1A IL6	3.81e-04	12	72	2	C0006625
Disease	uveitis (is_marker_for)	TNFRSF1A IL6	4.50e-04	13	72	2	DOID:13141 (is_marker_for)
Disease	uveitis (is_implicated_in)	TNFRSF1A IL6	4.50e-04	13	72	2	DOID:13141 (is_implicated_in)
Disease	systolic blood pressure, cigarettes per day measurement	NRXN3 GPC6	4.50e-04	13	72	2	EFO_0006335, EFO_0006525
Disease	Pneumoconiosis	ATR PTPRZ1	5.24e-04	14	72	2	C0032273
Disease	Bagassosis	ATR PTPRZ1	5.24e-04	14	72	2	C0004681
Disease	amyotrophic lateral sclerosis, age at onset	NRXN3 ANKS1B	6.04e-04	15	72	2	EFO_0004847, MONDO_0004976
Disease	isocitrate measurement	STK32A TRPM8	6.89e-04	16	72	2	EFO_0010505
Disease	multiple sclerosis (is_implicated_in)	KIF5A TNFRSF1A IL6	7.67e-04	73	72	3	DOID:2377 (is_implicated_in)
Disease	acute kidney failure (is_marker_for)	TNFRSF1A IL6	7.80e-04	17	72	2	DOID:3021 (is_marker_for)
Disease	infant grey matter volume measurement	ZMAT4 SLC35F4	8.76e-04	18	72	2	EFO_0008368
Disease	short-term memory	EPHX2 ANKS1B ZDBF2	1.11e-03	83	72	3	EFO_0004335
Disease	Lung Injury	TNFRSF1A IL6	1.20e-03	21	72	2	C0273115
Disease	Chronic Lung Injury	TNFRSF1A IL6	1.20e-03	21	72	2	C2350344
Disease	blood pressure	SYNE1 GPC6	1.31e-03	22	72	2	EFO_0004325
Disease	Respiratory Hypersensitivity	HRH1 IL6	1.31e-03	22	72	2	C0035228
Disease	Schizophrenia	EPHX2 DLGAP1 NRXN3 PTPRZ1 HRH1 TNFRSF1A IL6 PCM1	1.38e-03	883	72	8	C0036341
Disease	Hepatolenticular Degeneration	ANKS1B IL6	1.57e-03	24	72	2	C0019202
Disease	Hepatic Form of Wilson Disease	ANKS1B IL6	1.57e-03	24	72	2	C1527352
Disease	chronic obstructive pulmonary disease (is_marker_for)	BAMBI TNFRSF1A IL6	1.74e-03	97	72	3	DOID:3083 (is_marker_for)
Disease	sciatic neuropathy (biomarker_via_orthology)	PTN TNFRSF1A IL6	1.85e-03	99	72	3	DOID:11446 (biomarker_via_orthology)
Disease	Fever	TNFRSF1A IL6	1.98e-03	27	72	2	C0015967
Disease	cholesteryl esters:total lipids ratio, intermediate density lipoprotein measurement	SYNE2 LRP4 SPG11	2.07e-03	103	72	3	EFO_0008595, EFO_0020944
Disease	gastric adenocarcinoma (is_marker_for)	PTPRZ1 IL6	2.13e-03	28	72	2	DOID:3717 (is_marker_for)
Disease	obstructive sleep apnea (is_marker_for)	TNFRSF1A IL6	2.28e-03	29	72	2	DOID:0050848 (is_marker_for)
Disease	lower face morphology measurement	ROR2 LTBP1 TFPI	2.43e-03	109	72	3	EFO_0010948

Protein segments in the cluster

Peptide	Gene	Start	Entry
KKLECESSCIMNATG	USP26	231	Q9BXU7
DCDVQCKAKRDFLMS	ATAD5	826	Q96QE3
NSMDSVDSCCSLKKT	AKAP1	576	Q92667
RDRCETQCQMKKAEH	ANKRD30B	1266	Q9BXX2
NMRDAKCGKIQCQSS	ADAM19	566	Q9H013
MTCNNLSCVKELKDH	ARMH2	181	H3BNL8
MCLNTSDLQCLNKDS	ABCA12	1816	Q86UK0
QAMVKSESCQQERSC	DLGAP1	301	O14490
DICSSKEKCNMLGLS	ADAMTS20	361	P59510
RTGAECKQTMKTQRC	PTN	71	P21246
ANKVSCAMTDEICRL	MFN1	406	Q8IWA4
TQDACAKMRANCQKS	ANKS1B	1081	Q7Z6G8
KCTNTLACLNLDTMA	HCFC1	291	P51610
DCRSKEQMSDCSNTR	LY6G5C	106	Q5SRR4
SSNINSDNCLKMLCE	KIF18A	736	Q8NI77
KSVKTRQCCFNMLTE	CAND1	446	Q86VP6
MERCLRNSKCIDTES	EXOSC9	106	Q06265
KTEAESNSNMRCTCR	PCM1	1531	Q15154
CDELNNRMSLCKNAK	LTBP1	1666	Q14766
NRMSLCKNAKCINTD	LTBP1	1671	Q14766
MAAQRNRSKESKDCS	PCDHGA10	1	Q9Y5H3
DTKMKDRCKGSTCNR	CRISPLD2	291	Q9H0B8
NDADTCRKKMQAAST	DNAH8	3341	Q96JB1
MVNLDCIRINCNSSK	NRXN3	746	Q9Y4C0
KSEDATFMCDKRCNK	NFX1	676	Q12986
LSANKIEDLSCVSCM	LRGUK	156	Q96M69
RMQKCVNSCKSSAEV	HEG1	1146	Q9ULI3
KCMSCSSYRESQEKV	PTPRZ1	1441	P23471
EKNCSRAATVMINCL	MROH1	1066	Q8NDA8
KVKQCRCMSVNLSDS	GREM2	151	Q9H772
NMNCRTFKDCQHKSK	ATR	511	Q13535
HQRCSSSMKQTCKQE	GABRR3	31	A8MPY1
LMEENCRKCSETAKV	EPHX2	66	P34913
CCTTEMEDKLSQQSK	GPC6	66	Q9Y625
NDQLTKKCSELSCML	CCDC150	346	Q8NCX0
CLTCDKMRQADLSND	BAMBI	226	Q13145
IIMKCAFSKETNCQT	CYP4X1	191	Q8N118
NIKEESNCCMYSDKR	HOXD10	106	P28358
SNCCMYSDKRNKLIS	HOXD10	111	P28358
MEAGKLSKSCNITEC	MACC1	26	Q6ZN28
MAETNNECSIKVLCR	KIF5A	1	Q12840
SSCLLEDKMCEGNKT	HRH1	6	P35367
ECGKKEMSLSDCLNR	CENPI	321	Q92674
CNSAMKNINKHTKRC	RNASE7	51	Q9H1E1
KAMLSCNRSGKKDTC	SCUBE3	411	Q8IX30
PRKCNMTEEQSKNLC	ITGBL1	401	O95965
ASMVQKCKLCARENS	CZIB	61	Q9NWV4
ALRKETCNKSNMCES	IL6	66	P05231
TCNKSNMCESSKEAL	IL6	71	P05231
CSRDKNCVMSRKQRN	NR6A1	96	Q15406
MDKSLLCLLCSNSQE	TRIM43	106	Q96BQ3
DLLCSMCDLSNASVK	SYNE1	4091	Q8NF91
LASAKQEMECCLNSI	SYNE2	2346	Q8WXH0
QEMECCLNSILKSKR	SYNE2	2351	Q8WXH0
DIACKANSMLLDTKC	TEKT2	376	Q9UIF3
CMCRNKQKASASTPQ	ROR2	426	Q01974
DMRKCDSSQTCLLQE	STK32A	336	Q8WU08
QENRIKARCLSCTSM	SLC35F4	146	A4IF30
TTMSLTARKRACCNN	TM4SF20	66	Q53R12
SKMDSDQVCNKCPQE	SPG11	1416	Q96JI7
MCALLNSISDTTKEC	ZNF451	1011	Q9Y4E5
HMVRDVSCKNCNSKL	YPEL5	66	P62699
RISIVKSNCSQCKRM	ZNF334	496	Q9HCZ1
KSNCSQCKRMNTKEN	ZNF334	501	Q9HCZ1
NMVSRLCESKKVCAA	MIPEP	556	Q99797
LCESKKVCAAADMQL	MIPEP	561	Q99797
QKCSVSSEMKFDCIS	ZDBF2	356	Q9HCK1
CCACLAKAMERSEQQ	SLC24A5	231	Q71RS6
DLLCCCSSMVSRKNK	RFPL2	136	O75678
NNAEDNKCVSCMSEK	NUP153	806	P49790
QNRFESLEECKKMCT	TFPI	91	P10646
SLEECKKMCTRDNAN	TFPI	96	P10646
RMISKRNKDNSTACS	ZC3H7A	581	Q8IWR0
KQDKVQHTVCMDCSS	USP3	76	Q9Y6I4
TKCSMCQKNADTRFE	ZMYM6	191	O95789
MGSLNLKCISRDCKN	SCN11A	276	Q9UI33
MDKSLLCLLCSNSQE	TRIM43B	106	A6NCK2
CNASMECDKCQRRQK	ZNF330	36	Q9Y3S2
ELCQTQSAMSKNCIK	USP34	3191	Q70CQ2
QSAMSKNCIKLLCED	USP34	3196	Q70CQ2
KNMESSVCCFKNEDN	TRPM8	1036	Q7Z2W7
SCSKCRKEMGQVEIS	TNFRSF1A	101	P19438
SDADMVDKNKCCTLC	ZMAT4	66	Q9H898
EQCDMRKCSDKEFRC	LRP4	141	O75096