Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	alpha-(1->3)-fucosyltransferase activity	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	4.25e-13	8	102	6	GO:0046920
GeneOntologyMolecularFunction	4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase activity	FUT3 FUT4 FUT5 FUT6 FUT7	1.88e-11	6	102	5	GO:0017083
GeneOntologyMolecularFunction	fucosyltransferase activity	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	4.45e-11	14	102	6	GO:0008417
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 KDM2B CYP4F12 NOS2	6.91e-06	194	102	8	GO:0016705
GeneOntologyMolecularFunction	heme binding	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12 NOS2	1.42e-05	154	102	7	GO:0020037
GeneOntologyMolecularFunction	tetrapyrrole binding	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12 NOS2	2.13e-05	164	102	7	GO:0046906
GeneOntologyMolecularFunction	3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity	FUT3 FUT5	2.58e-05	2	102	2	GO:0017060
GeneOntologyMolecularFunction	monooxygenase activity	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12 NOS2	2.75e-05	115	102	6	GO:0004497
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen	CYP4F8 CYP51A1 CYP4F12 NOS2	5.09e-05	40	102	4	GO:0016709
GeneOntologyMolecularFunction	hexosyltransferase activity	PIGZ FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	1.05e-04	211	102	7	GO:0016758
GeneOntologyMolecularFunction	glycosyltransferase activity	PIGZ XYLT2 FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	1.15e-04	288	102	8	GO:0016757
GeneOntologyMolecularFunction	alpha-tocopherol omega-hydroxylase activity	CYP4F8 CYP4F12	2.56e-04	5	102	2	GO:0052871
GeneOntologyMolecularFunction	sodium:bicarbonate symporter activity	SLC4A7 SLC4A10	3.82e-04	6	102	2	GO:0008510
GeneOntologyMolecularFunction	leukotriene-B4 20-monooxygenase activity	CYP4F8 CYP4F12	5.34e-04	7	102	2	GO:0050051
GeneOntologyMolecularFunction	alkane 1-monooxygenase activity	CYP4F8 CYP4F12	5.34e-04	7	102	2	GO:0018685
GeneOntologyMolecularFunction	symporter activity	SLC4A7 SLC6A16 SLC17A5 SLC22A4 SLC4A10	1.04e-03	150	102	5	GO:0015293
GeneOntologyMolecularFunction	arachidonate omega-hydroxylase activity	CYP4F8 CYP4F12	1.13e-03	10	102	2	GO:0052869
GeneOntologyMolecularFunction	fatty acid omega-hydroxylase activity	CYP4F8 CYP4F12	1.13e-03	10	102	2	GO:0120250
GeneOntologyMolecularFunction	long-chain fatty acid omega-hydroxylase activity	CYP4F8 CYP4F12	1.13e-03	10	102	2	GO:0102033
GeneOntologyMolecularFunction	iron ion binding	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.63e-03	166	102	5	GO:0005506
GeneOntologyMolecularFunction	endopeptidase activity	ADAMTS4 PRSS56 RHBDD2 MMP21 TMPRSS4 ASTL PRSS21 RHBDD3	1.63e-03	430	102	8	GO:0004175
GeneOntologyMolecularFunction	monoatomic cation:bicarbonate symporter activity	SLC4A7 SLC4A10	1.94e-03	13	102	2	GO:0140410
GeneOntologyMolecularFunction	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen	CYP4F8 CYP4F12	1.94e-03	13	102	2	GO:0016713
GeneOntologyMolecularFunction	aminoacyl-tRNA editing activity	TARS2 IARS2	2.26e-03	14	102	2	GO:0002161
GeneOntologyMolecularFunction	arachidonate binding	CYP4F8 CYP4F12	2.60e-03	15	102	2	GO:0050544
GeneOntologyMolecularFunction	serine-type endopeptidase activity	PRSS56 RHBDD2 TMPRSS4 PRSS21 RHBDD3	2.93e-03	190	102	5	GO:0004252
GeneOntologyMolecularFunction	icosanoid binding	CYP4F8 CYP4F12	2.96e-03	16	102	2	GO:0050542
GeneOntologyMolecularFunction	icosatetraenoic acid binding	CYP4F8 CYP4F12	2.96e-03	16	102	2	GO:0050543
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC4A7 SLC6A16 SLC22A7 SLC17A5 SLC22A4 SLC4A10	4.14e-03	296	102	6	GO:0015291
GeneOntologyMolecularFunction	serine-type peptidase activity	PRSS56 RHBDD2 TMPRSS4 PRSS21 RHBDD3	4.22e-03	207	102	5	GO:0008236
GeneOntologyMolecularFunction	serine hydrolase activity	PRSS56 RHBDD2 TMPRSS4 PRSS21 RHBDD3	4.66e-03	212	102	5	GO:0017171
GeneOntologyMolecularFunction	neurotransmitter transmembrane transporter activity	SLC6A16 SLC22A4	5.09e-03	21	102	2	GO:0005326
GeneOntologyBiologicalProcess	fucosylation	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	2.23e-10	18	102	6	GO:0036065
GeneOntologyBiologicalProcess	L-fucose catabolic process	FUT4 FUT5 FUT6 FUT7	6.97e-08	9	102	4	GO:0042355
GeneOntologyBiologicalProcess	fucose catabolic process	FUT4 FUT5 FUT6 FUT7	6.97e-08	9	102	4	GO:0019317
GeneOntologyBiologicalProcess	L-fucose metabolic process	FUT4 FUT5 FUT6 FUT7	1.16e-07	10	102	4	GO:0042354
GeneOntologyBiologicalProcess	oligosaccharide biosynthetic process	FUT3 FUT4 FUT5 FUT6 FUT7	4.11e-07	31	102	5	GO:0009312
GeneOntologyBiologicalProcess	fucose metabolic process	FUT4 FUT5 FUT6 FUT7	9.80e-07	16	102	4	GO:0006004
GeneOntologyBiologicalProcess	oligosaccharide metabolic process	FUT3 FUT4 FUT5 FUT6 FUT7	2.51e-05	70	102	5	GO:0009311
GeneOntologyBiologicalProcess	hexose catabolic process	FUT4 FUT5 FUT6 FUT7	1.37e-04	53	102	4	GO:0019320
GeneOntologyBiologicalProcess	membrane lipid metabolic process	PIGZ PIGF FUT3 FUT4 FUT5 FUT6 FUT7	1.43e-04	229	102	7	GO:0006643
GeneOntologyBiologicalProcess	lymphocyte migration into lymph node	FUT4 FUT7	1.44e-04	4	102	2	GO:0097022
GeneOntologyBiologicalProcess	monosaccharide catabolic process	FUT4 FUT5 FUT6 FUT7	1.82e-04	57	102	4	GO:0046365
GeneOntologyBiologicalProcess	lipoprotein biosynthetic process	LCAT ZDHHC1 PIGZ PIGF NMT2	1.83e-04	106	102	5	GO:0042158
GeneOntologyBiologicalProcess	detection of external stimulus	GPR88 GRM6 PKDREJ NMT2 STRC STRCP1	2.21e-04	173	102	6	GO:0009581
GeneOntologyBiologicalProcess	detection of abiotic stimulus	GPR88 GRM6 PKDREJ NMT2 STRC STRCP1	2.35e-04	175	102	6	GO:0009582
GeneOntologyBiologicalProcess	N-glycan fucosylation	FUT11 FUT6	2.40e-04	5	102	2	GO:0036071
GeneOntologyBiologicalProcess	macromolecule glycosylation	FUT11 SLC4A10 FUT3 FUT4 FUT5 FUT6 FUT7	2.57e-04	252	102	7	GO:0043413
GeneOntologyBiologicalProcess	protein glycosylation	FUT11 SLC4A10 FUT3 FUT4 FUT5 FUT6 FUT7	2.57e-04	252	102	7	GO:0006486
GeneOntologyBiologicalProcess	leukotriene B4 catabolic process	CYP4F8 CYP4F12	3.59e-04	6	102	2	GO:0036101
GeneOntologyBiologicalProcess	glycosylation	FUT11 SLC4A10 FUT3 FUT4 FUT5 FUT6 FUT7	3.90e-04	270	102	7	GO:0070085
GeneOntologyBiologicalProcess	glycoprotein biosynthetic process	XYLT2 FUT11 SLC4A10 FUT3 FUT4 FUT5 FUT6 FUT7	3.97e-04	357	102	8	GO:0009101
GeneOntologyBiologicalProcess	leukotriene B4 metabolic process	CYP4F8 CYP4F12	5.00e-04	7	102	2	GO:0036102
GeneOntologyBiologicalProcess	protein N-linked glycosylation	FUT3 FUT4 FUT5 FUT6	5.50e-04	76	102	4	GO:0006487
GeneOntologyCellularComponent	Golgi cisterna	ACP3 FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	4.44e-06	135	102	7	GO:0031985
GeneOntologyCellularComponent	Golgi cisterna membrane	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	6.69e-06	94	102	6	GO:0032580
GeneOntologyCellularComponent	Golgi stack	ACP3 FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	2.08e-05	171	102	7	GO:0005795
Domain	Glyco_transf_10	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	5.28e-13	8	99	6	PF00852
Domain	Glyco_tran_10_N	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	5.28e-13	8	99	6	PF17039
Domain	Glyco_trans_10	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	5.28e-13	8	99	6	IPR001503
Domain	Glyco_tran_10_N	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	5.28e-13	8	99	6	IPR031481
Domain	Cyt_P450_CS	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	8.86e-06	53	99	5	IPR017972
Domain	CYTOCHROME_P450	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.27e-05	57	99	5	PS00086
Domain	-	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.39e-05	58	99	5	1.10.630.10
Domain	p450	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.39e-05	58	99	5	PF00067
Domain	Cyt_P450	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.64e-05	60	99	5	IPR001128
Domain	Cyt_P450_E_grp-I	CYP4F8 CYP21A2 CYP24A1 CYP4F12	9.37e-05	45	99	4	IPR002401
Domain	p53-like_TF_DNA-bd	FUT3 FUT5 FUT6 FUT7	1.78e-04	53	99	4	IPR008967
Domain	NUT	NUTM2A NUTM2B	2.75e-04	5	99	2	IPR024310
Domain	DZF	ILF3 STRBP	2.75e-04	5	99	2	SM00572
Domain	NUT_N	NUTM2A NUTM2B	2.75e-04	5	99	2	IPR024309
Domain	Anion_exchange	SLC4A7 SLC4A10	2.75e-04	5	99	2	IPR001717
Domain	NUT	NUTM2A NUTM2B	2.75e-04	5	99	2	PF12881
Domain	DZF_dom	ILF3 STRBP	2.75e-04	5	99	2	IPR006561
Domain	DZF	ILF3 STRBP	2.75e-04	5	99	2	PF07528
Domain	DZF	ILF3 STRBP	2.75e-04	5	99	2	PS51703
Domain	ANION_EXCHANGER_2	SLC4A7 SLC4A10	5.74e-04	7	99	2	PS00220
Domain	ANION_EXCHANGER_1	SLC4A7 SLC4A10	5.74e-04	7	99	2	PS00219
Domain	Band3_cytoplasmic_dom	SLC4A7 SLC4A10	9.77e-04	9	99	2	IPR013769
Domain	Band_3_cyto	SLC4A7 SLC4A10	9.77e-04	9	99	2	PF07565
Domain	Rhomboid	RHBDD2 RHBDD3	9.77e-04	9	99	2	PF01694
Domain	-	SLC4A7 SLC4A10	9.77e-04	9	99	2	3.40.1100.10
Domain	Peptidase_S54_rhomboid_dom	RHBDD2 RHBDD3	9.77e-04	9	99	2	IPR022764
Domain	-	RHBDD2 RHBDD3	9.77e-04	9	99	2	1.20.1540.10
Domain	Orgcat_transp/SVOP	SLC22A7 SLC22A4	9.77e-04	9	99	2	IPR004749
Domain	Cyt_P450_E_grp-IV	CYP51A1 CYP4F12	1.22e-03	10	99	2	IPR002403
Domain	HCO3_cotransp	SLC4A7 SLC4A10	1.22e-03	10	99	2	PF00955
Domain	HCO3_transpt_C	SLC4A7 SLC4A10	1.22e-03	10	99	2	IPR011531
Domain	PTrfase/Anion_transptr	SLC4A7 SLC4A10	1.22e-03	10	99	2	IPR016152
Domain	HCO3_transpt_euk	SLC4A7 SLC4A10	1.22e-03	10	99	2	IPR003020
Domain	DSRM	ILF3 STRBP	4.48e-03	19	99	2	SM00358
Domain	Fd_Rdtase_FAD-bd	NOX1 NOS2	4.48e-03	19	99	2	IPR017927
Domain	FAD_FR	NOX1 NOS2	4.48e-03	19	99	2	PS51384
Domain	Riboflavin_synthase-like_b-brl	NOX1 NOS2	4.48e-03	19	99	2	IPR017938
Domain	dsrm	ILF3 STRBP	4.97e-03	20	99	2	PF00035
Domain	DS_RBD	ILF3 STRBP	5.47e-03	21	99	2	PS50137
Pathway	KEGG_MEDICUS_REFERENCE_SIALYL_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT3 FUT4 FUT5 FUT6 FUT7	1.25e-11	6	67	5	M47967
Pathway	REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	4.70e-10	21	67	6	M27917
Pathway	KEGG_MEDICUS_REFERENCE_LEWIS_X_ANTIGEN_BIOSYNTHESIS	FUT3 FUT4 FUT5 FUT6	2.32e-09	5	67	4	M47966
Pathway	KEGG_GLYCOSPHINGOLIPID_BIOSYNTHESIS_LACTO_AND_NEOLACTO_SERIES	FUT3 FUT4 FUT5 FUT6 FUT7	1.27e-07	26	67	5	M17377
Pathway	BIOCARTA_AMAN_PATHWAY	FUT4 FUT5 FUT6 FUT7	6.12e-07	15	67	4	M22009
Pathway	REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12	9.66e-06	104	67	6	M738
Pathway	REACTOME_PHASE_I_FUNCTIONALIZATION_OF_COMPOUNDS	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12	1.02e-05	105	67	6	MM14842
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.28e-05	64	67	5	M5650
Pathway	REACTOME_CYTOCHROME_P450_ARRANGED_BY_SUBSTRATE_TYPE	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.49e-05	66	67	5	MM14839
Pathway	REACTOME_BLOOD_GROUP_SYSTEMS_BIOSYNTHESIS	FUT11 FUT4 FUT7	6.65e-05	17	67	3	MM15629
Pathway	WP_OXIDATION_BY_CYTOCHROME_P450	CYP4F8 CYP24A1 CYP51A1 CYP4F12	2.11e-04	62	67	4	M39653
Pathway	REACTOME_METABOLISM_OF_CARBOHYDRATES	XYLT2 FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	4.21e-04	288	67	7	M16864
Pathway	WP_EICOSANOID_METABOLISM_VIA_CYCLOOXYGENASES_COX	CYP4F8 PTGS1 CYP4F12	5.06e-04	33	67	3	MM15918
Pathway	REACTOME_BIOLOGICAL_OXIDATIONS	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12	5.95e-04	219	67	6	MM14838
Pathway	REACTOME_BIOLOGICAL_OXIDATIONS	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12	6.09e-04	220	67	6	M10320
Pathway	BIOCARTA_AMAN_PATHWAY	FUT4 FUT7	7.84e-04	9	67	2	MM1535
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A7 SLC4A10	9.77e-04	10	67	2	M27335
Pathway	REACTOME_BICARBONATE_TRANSPORTERS	SLC4A7 SLC4A10	9.77e-04	10	67	2	MM15073
Pathway	WP_OXIDATION_BY_CYTOCHROME_P450	CYP21A2 CYP24A1 CYP51A1	1.11e-03	43	67	3	MM15873
Pathway	REACTOME_ORGANIC_CATION_ANION_ZWITTERION_TRANSPORT	SLC22A7 SLC22A4	1.42e-03	12	67	2	MM15192
Pathway	REACTOME_EICOSANOIDS	CYP4F8 CYP4F12	1.42e-03	12	67	2	M27129
Pathway	REACTOME_EICOSANOIDS	CYP4F8 CYP4F12	1.42e-03	12	67	2	MM14845
Pathway	WP_METAPATHWAY_BIOTRANSFORMATION_PHASE_I_AND_II	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.76e-03	183	67	5	M39588
Pubmed	Composition of Drosophila melanogaster proteome involved in fucosylated glycan metabolism.	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	3.21e-12	15	105	6	11698403
Pubmed	Distinct human α(1,3)-fucosyltransferases drive Lewis-X/sialyl Lewis-X assembly in human cells.	FUT3 FUT4 FUT5 FUT6	3.91e-10	5	105	4	29593094
Pubmed	Expression of human chromosome 19p alpha(1,3)-fucosyltransferase genes in normal tissues. Alternative splicing, polyadenylation, and isoforms.	FUT3 FUT5 FUT6	2.67e-08	3	105	3	7650030
Pubmed	Overexpressed N-fucosylation on the cell surface driven by FUT3, 5, and 6 promotes cell motilities in metastatic pancreatic cancer cell lines.	FUT3 FUT5 FUT6	2.67e-08	3	105	3	30808544
Pubmed	Physical maps of human alpha (1,3)fucosyltransferase genes FUT3-FUT6 on chromosomes 19p13.3 and 11q21.	FUT4 FUT5 FUT6	2.67e-08	3	105	3	7782074
Pubmed	Isolation of a novel human alpha (1,3)fucosyltransferase gene and molecular comparison to the human Lewis blood group alpha (1,3/1,4)fucosyltransferase gene. Syntenic, homologous, nonallelic genes encoding enzymes with distinct acceptor substrate specificities.	FUT3 FUT4 FUT5	2.67e-08	3	105	3	1740457
Pubmed	Activation of host antiviral RNA-sensing factors necessary for herpes simplex virus type 1-activated transcription of host cell fucosyltransferase genes FUT3, FUT5, and FUT6 and subsequent expression of sLe(x) in virus-infected cells.	FUT3 FUT5 FUT6	1.07e-07	4	105	3	19349624
Pubmed	Comparative expression profiling of 40 mouse cytochrome P450 genes in embryonic and adult tissues.	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	2.25e-07	44	105	5	12745259
Pubmed	Comparison of cytochrome P450 (CYP) genes from the mouse and human genomes, including nomenclature recommendations for genes, pseudogenes and alternative-splice variants.	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	2.36e-06	70	105	5	15128046
Pubmed	Lack of functional selectin ligand interactions compromises long term tumor protection by CD8+ T cells.	FUT4 FUT7	9.03e-06	2	105	2	22359671
Pubmed	α(1,3)-Fucosyltransferases FUT4 and FUT7 control murine susceptibility to thrombosis.	FUT4 FUT7	9.03e-06	2	105	2	23562273
Pubmed	Lack of functional selectin-ligand interactions enhances innate immune resistance to systemic Listeria monocytogenes infection.	FUT4 FUT7	9.03e-06	2	105	2	29345354
Pubmed	NOX1 abet mesangial fibrogenesis via iNOS induction in diabetes.	NOX1 NOS2	9.03e-06	2	105	2	23801050
Pubmed	The alpha(1,3)fucosyltransferase Fuc-TVII controls leukocyte trafficking through an essential role in L-, E-, and P-selectin ligand biosynthesis.	FUT4 FUT7	9.03e-06	2	105	2	8752218
Pubmed	Fucosyltransferase 4 and 7 mediates adhesion of non-small cell lung cancer cells to brain-derived endothelial cells and results in modification of the blood-brain-barrier: in vitro investigation of CD15 and CD15s in lung-to-brain metastasis.	FUT4 FUT7	9.03e-06	2	105	2	31104223
Pubmed	The alpha(1,3)fucosyltransferases FucT-IV and FucT-VII exert collaborative control over selectin-dependent leukocyte recruitment and lymphocyte homing.	FUT4 FUT7	9.03e-06	2	105	2	11485743
Pubmed	Abrogation of functional selectin-ligand expression reduces migration of pathogenic CD8+ T cells into heart.	FUT4 FUT7	9.03e-06	2	105	2	16709814
Pubmed	Down-regulation of FUT3 and FUT5 by shRNA alters Lewis antigens expression and reduces the adhesion capacities of gastric cancer cells.	FUT3 FUT5	9.03e-06	2	105	2	21978830
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	9.03e-06	2	105	2	11687802
Pubmed	Inducible nitric oxide synthase and cyclooxygenase-2 participate in anti-inflammatory and analgesic effects of the natural marine compound lemnalol from Formosan soft coral Lemnalia cervicorni.	PTGS1 NOS2	9.03e-06	2	105	2	17916350
Pubmed	Memory T cells are enriched in lymph nodes of selectin-ligand-deficient mice.	FUT4 FUT7	9.03e-06	2	105	2	20937846
Pubmed	Correlation of FUT3 and FUT6 Gene Polymorphisms With Helicobacter pylori Infection.	FUT3 FUT6	9.03e-06	2	105	2	39108208
Pubmed	Oxygenation of polyunsaturated long chain fatty acids by recombinant CYP4F8 and CYP4F12 and catalytic importance of Tyr-125 and Gly-328 of CYP4F8.	CYP4F8 CYP4F12	9.03e-06	2	105	2	16112640
Pubmed	Hypoxia induces nitric oxide synthase in rheumatoid synoviocytes: consequences on NADPH oxidase regulation.	NOX1 NOS2	9.03e-06	2	105	2	22329647
Pubmed	iNOS- and NOX1-dependent ROS production maintains bacterial homeostasis in the ileum of mice.	NOX1 NOS2	9.03e-06	2	105	2	29210363
Pubmed	The biosynthesis of the selectin-ligand sialyl Lewis x in colorectal cancer tissues is regulated by fucosyltransferase VI and can be inhibited by an RNA interference-based approach.	FUT4 FUT6	9.03e-06	2	105	2	20965272
Pubmed	Selectin ligand-independent priming and maintenance of T cell immunity during airborne tuberculosis.	FUT4 FUT7	9.03e-06	2	105	2	16394002
Pubmed	Type I Streptococcus pneumoniae carbohydrate utilizes a nitric oxide and MHC II-dependent pathway for antigen presentation.	HLA-DMA NOS2	9.03e-06	2	105	2	18778282
Pubmed	Site-specific fucosylation of sialylated polylactosamines by alpha1,3/4-fucosyltransferases-V and -VI Is defined by amino acids near the N terminus of the catalytic domain.	FUT5 FUT6	9.03e-06	2	105	2	17604274
Pubmed	Acceptor specificity of different length constructs of human recombinant alpha 1,3/4-fucosyltransferases. Replacement of the stem region and the transmembrane domain of fucosyltransferase V by protein A results in an enzyme with GDP-fucose hydrolyzing activity.	FUT3 FUT5	9.03e-06	2	105	2	7721776
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	9.03e-06	2	105	2	34910522
Pubmed	Chronic continuous hypoxia decreases the expression of SLC4A7 (NBCn1) and SLC4A10 (NCBE) in mouse brain.	SLC4A7 SLC4A10	9.03e-06	2	105	2	17928512
Pubmed	Synthesis of {alpha}(1,3) fucosyltransferases IV- and VII-dependent eosinophil selectin ligand and recruitment to the skin.	FUT4 FUT7	9.03e-06	2	105	2	16127157
Pubmed	Regulation of PSGL-1 interactions with L-selectin, P-selectin, and E-selectin: role of human fucosyltransferase-IV and -VII.	FUT4 FUT7	9.03e-06	2	105	2	15579466
Pubmed	Fuc-TVII is required for T helper 1 and T cytotoxic 1 lymphocyte selectin ligand expression and recruitment in inflammation, and together with Fuc-TIV regulates naive T cell trafficking to lymph nodes.	FUT4 FUT7	9.03e-06	2	105	2	11535629
Pubmed	Fucosyltransferase Induction during Influenza Virus Infection Is Required for the Generation of Functional Memory CD4+ T Cells.	FUT4 FUT7	9.03e-06	2	105	2	29491007
Pubmed	Molecular cloning of a fourth member of a human alpha (1,3)fucosyltransferase gene family. Multiple homologous sequences that determine expression of the Lewis x, sialyl Lewis x, and difucosyl sialyl Lewis x epitopes.	FUT5 FUT6	9.03e-06	2	105	2	1339443
Pubmed	Fucosyltransferase IV and VII-directed selectin ligand function determines long-term survival in experimental tuberculosis.	FUT4 FUT7	9.03e-06	2	105	2	19608009
Pubmed	Human endogenous retrovirus W env increases nitric oxide production and enhances the migration ability of microglia by regulating the expression of inducible nitric oxide synthase.	ERVW-1 NOS2	9.03e-06	2	105	2	28656540
Pubmed	Pathophysiological contributions of fucosyltransferases in renal ischemia reperfusion injury.	FUT4 FUT7	9.03e-06	2	105	2	12193737
Pubmed	Silencing α1,3-fucosyltransferases in human leukocytes reveals a role for FUT9 enzyme during E-selectin-mediated cell adhesion.	FUT4 FUT7	2.70e-05	3	105	2	23192350
Pubmed	Negative regulation of beta4 integrin transcription by homeodomain-interacting protein kinase 2 and p53 impairs tumor progression.	HIPK2 ITGB4	2.70e-05	3	105	2	19567674
Pubmed	Murine neutrophils require alpha1,3-fucosylation but not PSGL-1 for productive infection with Anaplasma phagocytophilum.	FUT4 FUT7	2.70e-05	3	105	2	12869507
Pubmed	The clinicopathologic features of YWHAE-FAM22 endometrial stromal sarcomas: a histologically high-grade and clinically aggressive tumor.	NUTM2A NUTM2B	2.70e-05	3	105	2	22456610
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	2.70e-05	3	105	2	30801007
Pubmed	The association of four common polymorphisms from four candidate genes (COX-1, COX-2, ITGA2B, ITGA2) with aspirin insensitivity: a meta-analysis.	ITGA2B PTGS1	2.70e-05	3	105	2	24244288
Pubmed	A new double-stranded RNA-binding protein that interacts with PKR.	ILF3 STRBP	2.70e-05	3	105	2	10684936
Pubmed	Platelet regulation by NO/cGMP signaling and NAD(P)H oxidase-generated ROS.	ITGA2B NOX1	2.70e-05	3	105	2	16469512
Pubmed	FUT family mediates the multidrug resistance of human hepatocellular carcinoma via the PI3K/Akt signaling pathway.	FUT4 FUT6	2.70e-05	3	105	2	24232099
Pubmed	A role for leukocyte-endothelial adhesion mechanisms in epilepsy.	FUT4 FUT7	2.70e-05	3	105	2	19029985
Pubmed	Efficient recruitment of lymphocytes in inflamed brain venules requires expression of cutaneous lymphocyte antigen and fucosyltransferase-VII.	FUT4 FUT7	2.70e-05	3	105	2	15843584
Pubmed	Cloning and expression of cyclosporin A- and FK506-sensitive nuclear factor of activated T-cells: NF45 and NF90.	ILF3 STRBP	2.70e-05	3	105	2	7519613
Pubmed	Naïve T cells re-distribute to the lungs of selectin ligand deficient mice.	FUT4 FUT7	2.70e-05	3	105	2	20532047
Pubmed	Suppression of tumor formation in lymph nodes by L-selectin-mediated natural killer cell recruitment.	FUT4 FUT7	2.70e-05	3	105	2	16352740
Pubmed	Difucosylated oligosaccharide Lewis Y is contained within integrin αvβ3 on RL95-2 cells and required for endometrial receptivity.	FUT3 FUT4	2.70e-05	3	105	2	20605574
Pubmed	T-cell P/E-selectin ligand alpha(1,3)fucosylation is not required for graft-vs-host disease induction.	FUT4 FUT7	2.70e-05	3	105	2	16338500
Pubmed	Development of immunohistochemistry assays to assess GALNT14 and FUT3/6 in clinical trials of dulanermin and drozitumab.	FUT3 FUT6	2.70e-05	3	105	2	20179215
Pubmed	Binding of L-selectin to its vascular and extravascular ligands is differentially regulated by pH.	FUT4 FUT7	2.70e-05	3	105	2	21982762
Pubmed	Alpha(1,3)fucosyltransferases FucT-IV and FucT-VII control susceptibility to atherosclerosis in apolipoprotein E-/- mice.	FUT4 FUT7	2.70e-05	3	105	2	15308551
Pubmed	Metastatic growth progression caused by PSGL-1-mediated recruitment of monocytes to metastatic sites.	FUT4 FUT7	2.70e-05	3	105	2	24322980
Pubmed	CD15 expression in mature granulocytes is determined by alpha 1,3-fucosyltransferase IX, but in promyelocytes and monocytes by alpha 1,3-fucosyltransferase IV.	FUT4 FUT7	2.70e-05	3	105	2	11278338
Pubmed	Endothelial E-selectin inhibition improves acute myeloid leukaemia therapy by disrupting vascular niche-mediated chemoresistance.	FUT4 FUT7	2.70e-05	3	105	2	32341362
Pubmed	Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target.	NOX1 NOS2	2.70e-05	3	105	2	25317947
Pubmed	α(1,3) Fucosyltransferases IV and VII are essential for the initial recruitment of basophils in chronic allergic inflammation.	FUT4 FUT7	2.70e-05	3	105	2	23657464
Pubmed	The interaction between inhibitors of nitric oxide synthase and cyclooxygenase in formalin-induced pain in mice: an isobolographic study.	PTGS1 NOS2	2.70e-05	3	105	2	18292449
Pubmed	Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.	FUT4 FUT7	2.70e-05	3	105	2	22388819
Pubmed	The clinical phenotype of YWHAE-NUTM2B/E positive pediatric clear cell sarcoma of the kidney.	NUTM2E NUTM2B	2.70e-05	3	105	2	26542179
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	5.40e-05	4	105	2	18849963
Pubmed	Monocyte Induction of E-Selectin-Mediated Endothelial Activation Releases VE-Cadherin Junctions to Promote Tumor Cell Extravasation in the Metastasis Cascade.	FUT4 FUT7	5.40e-05	4	105	2	27488527
Pubmed	Anticancer Mechanisms in Two Murine Bone Marrow-Derived Dendritic Cell Subsets Activated with TLR4 Agonists.	NOX1 NOS2	5.40e-05	4	105	2	29500244
Pubmed	miR-125a-3p/FUT5-FUT6 axis mediates colorectal cancer cell proliferation, migration, invasion and pathological angiogenesis via PI3K-Akt pathway.	FUT5 FUT6	5.40e-05	4	105	2	28771224
Pubmed	Disruption of mouse cytochrome p450 4f14 (Cyp4f14 gene) causes severe perturbations in vitamin E metabolism.	CYP4F8 CYP4F12	5.40e-05	4	105	2	22665481
Pubmed	The Lewis X-related α1,3-fucosyltransferase, Fut10, is required for the maintenance of stem cell populations.	FUT4 FUT7	5.40e-05	4	105	2	23986452
Pubmed	A SCL4A10 gene product maps selectively to the basolateral plasma membrane of choroid plexus epithelial cells.	SLC4A7 SLC4A10	5.40e-05	4	105	2	14592810
Pubmed	Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.	CYP4F8 CYP4F12	5.40e-05	4	105	2	11185557
Pubmed	Arteriogenesis proceeds via ICAM-1/Mac-1- mediated mechanisms.	FUT4 FUT7	5.40e-05	4	105	2	15059933
Pubmed	Cellular players and role of selectin ligands in leukocyte recruitment in a T-cell-initiated delayed-type hypersensitivity reaction.	FUT4 FUT7	5.40e-05	4	105	2	18755847
Pubmed	A novel monoclonal antibody against 6-sulfo sialyl Lewis x glycans attenuates murine allergic rhinitis by suppressing Th2 immune responses.	FUT4 FUT7	5.40e-05	4	105	2	37735247
Pubmed	Heparin-induced leukocytosis requires 6-O-sulfation and is caused by blockade of selectin- and CXCL12 protein-mediated leukocyte trafficking in mice.	FUT4 FUT7	5.40e-05	4	105	2	22194593
Pubmed	Nitric oxide: a prostaglandin H synthase 1 and 2 reducing cosubstrate that does not stimulate cyclooxygenase activity or prostaglandin H synthase expression in murine macrophages.	PTGS1 NOS2	5.40e-05	4	105	2	8914934
Pubmed	Specialized contributions by alpha(1,3)-fucosyltransferase-IV and FucT-VII during leukocyte rolling in dermal microvessels.	FUT4 FUT7	5.40e-05	4	105	2	10894166
Pubmed	Notch-dependent control of myelopoiesis is regulated by fucosylation.	FUT4 FUT7	5.40e-05	4	105	2	18359890
Pubmed	Relative positions of two clusters of human alpha-L-fucosyltransferases in 19q (FUT1-FUT2) and 19p (FUT6-FUT3-FUT5) within the microsatellite genetic map of chromosome 19.	FUT3 FUT6	5.40e-05	4	105	2	7656588
Pubmed	Expression of functional P-selectin glycoprotein ligand 1 on hematopoietic progenitors is developmentally regulated.	FUT4 FUT7	5.40e-05	4	105	2	22461691
Pubmed	Involvement of protein kinase Czeta in interleukin-1beta induction of ADAMTS-4 and type 2 nitric oxide synthase via NF-kappaB signaling in primary human osteoarthritic chondrocytes.	ADAMTS4 NOS2	5.40e-05	4	105	2	18050214
Pubmed	Skin-homing receptors on effector leukocytes are differentially sensitive to glyco-metabolic antagonism in allergic contact dermatitis.	FUT4 FUT7	5.40e-05	4	105	2	18056398
Pubmed	Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.	ILF3 ADAMTS4 STRBP HIPK2 TARS2 FUT11 PRSS21 FUT4 FUT7 MTMR9	7.50e-05	730	105	10	34857952
Pubmed	Immunocytochemical identification of electroneutral Na⁺-coupled HCO₃⁻ transporters in freshly dissociated mouse medullary raphé neurons.	SLC4A7 SLC4A10	8.97e-05	5	105	2	23500099
Pubmed	Disruption of P450-mediated vitamin E hydroxylase activities alters vitamin E status in tocopherol supplemented mice and reveals extra-hepatic vitamin E metabolism.	CYP4F8 CYP4F12	8.97e-05	5	105	2	22969154
Pubmed	The sphingosine 1-phosphate receptor 1 causes tissue retention by inhibiting the entry of peripheral tissue T lymphocytes into afferent lymphatics.	FUT4 FUT7	8.97e-05	5	105	2	18037890
Pubmed	N-acetylglucosamine-6-O-sulfotransferases 1 and 2 cooperatively control lymphocyte homing through L-selectin ligand biosynthesis in high endothelial venules.	FUT4 FUT7	8.97e-05	5	105	2	16227985
Pubmed	Changes of renal vitamin D metabolic enzyme expression and calcium transporter abundance in obstructive nephropathy.	CYP21A2 CYP24A1	8.97e-05	5	105	2	22029643
Pubmed	Cytochrome P4504f, a potential therapeutic target limiting neuroinflammation.	CYP4F8 CYP4F12	8.97e-05	5	105	2	21466787
Pubmed	Population genetic data on four STR loci, PAI (CA)n, GpIIIa (CT)n, PLAT (TG)14 (CA)12, and NOS2A (CCTTT)n, in Mediterranean populations.	ITGA2B NOS2	8.97e-05	5	105	2	17320454
Pubmed	Both inducible nitric oxide synthase and NADPH oxidase contribute to the control of virulent phase I Coxiella burnetii infections.	NOX1 NOS2	8.97e-05	5	105	2	15501800
Pubmed	Genetic polymorphisms in mediators of inflammation and gastric precancerous lesions.	PTGS1 NOS2	8.97e-05	5	105	2	18287876
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	8.97e-05	5	105	2	24920589
Pubmed	Bone Morphogenic Protein 4 Mediates NOX1-Dependent eNOS Uncoupling, Endothelial Dysfunction, and COX2 Induction in Type 2 Diabetes Mellitus.	NOX1 NOS2	8.97e-05	5	105	2	26121233
Pubmed	Novel anti-carbohydrate antibodies reveal the cooperative function of sulfated N- and O-glycans in lymphocyte homing.	FUT4 FUT7	1.34e-04	6	105	2	20929857
Pubmed	The rhomboid protease family: a decade of progress on function and mechanism.	RHBDD2 RHBDD3	1.34e-04	6	105	2	22035660
Cytoband	7q21.2	CYP51A1 ERVW-1	5.34e-04	15	105	2	7q21.2
Cytoband	19q13.32	RTN2 ZNF296 PPM1N	6.70e-04	74	105	3	19q13.32
Cytoband	10q23.2	NUTM2A NUTM2D	6.89e-04	17	105	2	10q23.2
GeneFamily	Fucosyltransferases\|Blood group antigens	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	2.60e-12	13	64	6	434
GeneFamily	Cytochrome P450 family 4	CYP4F8 CYP4F30P CYP4F12	2.78e-04	36	64	3	1003
GeneFamily	Rhomboid family	RHBDD2 RHBDD3	1.09e-03	14	64	2	926
GeneFamily	Proteases, serine	PRSS56 TMPRSS4 PRSS21	1.44e-03	63	64	3	738
GeneFamily	Glycosyl transferases group 1 domain containing\|Phosphatidylinositol glycan anchor biosynthesis	PIGZ PIGF	2.48e-03	21	64	2	680
GeneFamily	G protein-coupled receptors, Class A orphans	GPR101 GPR88 GPR146	2.66e-03	78	64	3	262
GeneFamily	Solute carriers	SLC4A7 SLC6A16 SLC22A7 SLC17A5 SLC22A4 SLC4A10	2.70e-03	395	64	6	752
GeneFamily	Actins\|Deafness associated genes	SLC22A4 ILDR1 STRC	7.51e-03	113	64	3	1152
GeneFamily	Glycosyltransferase family 6\|Blood group antigens	ERMAP FUT3	7.59e-03	37	64	2	454
Coexpression	WAGNER_APO2_SENSITIVITY	FUT11 FUT3 FUT4 FUT5 FUT6 FUT7	7.28e-10	26	104	6	M13240
Coexpression	GSE6259_33D1_POS_VS_DEC205_POS_SPLENIC_DC_DN	PXMP4 HIPK2 GPR146 SLC17A5 NYNRIN SLC22A4 FUT7	1.44e-05	198	104	7	M6731
Coexpression	GSE9946_MATURE_STIMULATORY_VS_LISTERIA_INF_MATURE_DC_DN	SLC6A16 CYP51A1 LCAT NPHP3 SLC22A4 FUT7	1.47e-05	132	104	6	M425
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CYP21A2 CYP24A1 SLC22A7 FUT3 FUT6 TMEM82	3.84e-06	176	105	6	1595dbeee336a81e581325d63208ec6262664ee9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYP24A1 TMPRSS4 PIGZ ITGB4 SYT8 CYP4F12	4.66e-06	182	105	6	678eadd57e7e830fc2bf9fd35616d3badce01705
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-papillary_tips_cell-Papillary_Tip_Epithelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CYP24A1 TMPRSS4 PIGZ ITGB4 SYT8 CYP4F12	4.66e-06	182	105	6	8d1229fa5aa6e2e38f2ac6fe4f4dc89752fe9344
ToppCell	distal-Epithelial-Proximal_Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 PKP3 ILDR1 FUT3 FUT6	7.12e-06	196	105	6	c102b28d5d1d90b9f7024cb51114276354be26a5
ToppCell	Basal_cells-Myositis-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CYP24A1 TMPRSS4 ITGB4 SYT8 NYNRIN PLXNB1	7.12e-06	196	105	6	3b66f3a79b3f2ebacb4ad646f179e505ab38d6f0
ToppCell	distal-Epithelial-Proximal_Basal-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 PKP3 ILDR1 FUT3 FUT6	7.12e-06	196	105	6	a543d4623096cb3f9170dbf7af52381e77aa435e
ToppCell	distal-3-Epithelial-Proximal_Basal\|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 SYT8 ILDR1 FUT3 FUT6	7.12e-06	196	105	6	7e1a565dd2da4f375cbce8842ba4fd6c22ac8375
ToppCell	Basal_cells\|World / lung cells shred on cell class, cell subclass, sample id	CYP24A1 TMPRSS4 ITGB4 SYT8 NYNRIN PLXNB1	7.33e-06	197	105	6	24360b660000bdfb999d58fbf4e29585a97e1785
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pax5_(SN/VTA_(SNr))--\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MMP21 TMPRSS4 LIME1 ERMAP	7.51e-06	53	105	4	ef2fa0364d7807cec2c0a45f940837cac6d22e43
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pax5_(SN/VTA_(SNr))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MMP21 TMPRSS4 LIME1 ERMAP	7.51e-06	53	105	4	974757404e411d7a0d762d21db07f9632a838be3
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Pax5_(SN/VTA_(SNr))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	MMP21 TMPRSS4 LIME1 ERMAP	7.51e-06	53	105	4	ad3eac1ffca39ace1ea1284441c60fe55b1a8470
ToppCell	Basal_cells-SSc-ILD_01\|World / lung cells shred on cell class, cell subclass, sample id	CYP24A1 TMPRSS4 ITGB4 SYT8 APCDD1L	4.36e-05	164	105	5	85487a303194f5244956ec1ca2d1758d38117f41
ToppCell	TCGA-Colorectal\|World / Sample_Type by Project: Shred V9	PIGZ NOX1 FUT3 FUT4 NOS2	4.61e-05	166	105	5	c018cd8c7a82251c67e3dc812d4d21e527a43456
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X	CYP24A1 TMPRSS4 SYT8 C1orf159 INCA1	5.17e-05	170	105	5	aabe993c9f337b1caaeb0e64626a3920579c41b7
ToppCell	Transplant_Alveoli_and_parenchyma-Epithelial-Basal_1\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	CYP24A1 TMPRSS4 SYT8 C1orf159 INCA1	5.46e-05	172	105	5	b66dbfff5e4f53ca8ece91ff9c5dc66a71f07c63
ToppCell	RSV-Healthy-1\|Healthy / Virus stimulation, Condition and Cluster	PXMP4 ADAMTS4 NPHP3 ERMAP PLXNB1	5.93e-05	175	105	5	ff3a27f512a3a710ebc863b7b75cce8167d5440b
ToppCell	RSV-Healthy-1\|RSV / Virus stimulation, Condition and Cluster	PXMP4 ADAMTS4 NPHP3 ERMAP PLXNB1	5.93e-05	175	105	5	ca52b99b03535a5b3a2751d6981708dc5b255b91
ToppCell	3'-GW_trimst-2-LargeIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THEMIS2 GPR146 SH3TC1 FUT7 NOS2	6.26e-05	177	105	5	d6596a0b6fd146fefc27717c1a7dbaa3774cc644
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THEMIS2 ITGA2B PTGS1 GPR146 SH3TC1	6.43e-05	178	105	5	4ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	THEMIS2 ITGA2B PTGS1 GPR146 SH3TC1	6.43e-05	178	105	5	c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell	droplet-Marrow-nan-24m-Lymphocytic-naive_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGA2B GRM6 PKP3 FUT7 PLXNB1	6.43e-05	178	105	5	cc0382b0ee1e6c76522e2c86ad1425c45debab5d
ToppCell	Children_(3_yrs)-Epithelial-basal_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CYP24A1 TMPRSS4 ITGB4 SYT8 PLXNB1	6.43e-05	178	105	5	fba2e38c05cbf031e0c6d47b1602575fea734a57
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)--\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SYT8 PKP3 ALPK3 IL27RA	6.97e-05	93	105	4	38a075f06001a2fd1ec77fc301a08a87618a2440
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)-\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SYT8 PKP3 ALPK3 IL27RA	6.97e-05	93	105	4	a0117b12889d9c48294a7ccea4284d00c087889f
ToppCell	Entopeduncular-Endothelial-ENDOTHELIAL_STALK-Flt1_1-Endothelial_Stalk.Flt1.Gkn3_(Gkn3)\|Entopeduncular / BrainAtlas - Mouse McCarroll V32	SYT8 PKP3 ALPK3 IL27RA	6.97e-05	93	105	4	b3e057132633b25bd4f8ff2c0aa203ade0f3ba4c
ToppCell	wk_08-11-Hematologic-Myeloid-pre-pDC/DC5\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ACP3 GPR88 GPR146 LIME1 ZNF296	7.14e-05	182	105	5	fec8a2d6d4099722b8e1bb41222108ed74268fcf
ToppCell	droplet-Tongue-nan-24m-Epithelial-parabasal\|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYP51A1 RTN2 PTGS1 SLIT1 PPM1N	7.91e-05	186	105	5	18c06041c6c8a0ebac17b3c8aaebd67e652d315a
ToppCell	COVID-19-Epithelial_cells-Airway_basal\|COVID-19 / group, cell type (main and fine annotations)	CYP24A1 TMPRSS4 ITGB4 SYT8 PLXNB1	8.11e-05	187	105	5	8407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCell	Pericytes-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS4 TRPC4 EGFL6 SLIT1 CDH8	8.32e-05	188	105	5	f16ff998393bf1954bbf10caab15173bdb104ac1
ToppCell	-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	ADAMTS4 TRPC4 ASTL GPR88 EGFL6	8.32e-05	188	105	5	038f48e8daaeb72716e975d22a6b004a90654960
ToppCell	Basal_cells-IPF_02\|World / lung cells shred on cell class, cell subclass, sample id	CYP24A1 TMPRSS4 ITGB4 SYT8 PLXNB1	8.96e-05	191	105	5	a98915bad9a4a61dd4cbca798914849b805f4a19
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-H_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	CYP24A1 TMPRSS4 ITGB4 EGFL6 SYT8	9.18e-05	192	105	5	7a6dd2ae217b8f8e460d47ad128904408299458c
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|COVID-19 / Condition, Lineage and Cell class	CYP24A1 TMPRSS4 ITGB4 FUT6 NOS2	1.01e-04	196	105	5	dd32046067d93b9484cfbf1d7826a436a3d9f0e9
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMPRSS4 SYT8 PKP3 CYP4F12 NOS2	1.01e-04	196	105	5	5789b5b0763d6eab21bf4da1fd8eae6116f46f3f
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMPRSS4 CYP4F12 FUT3 FUT6 NOS2	1.01e-04	196	105	5	a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	TMPRSS4 CYP4F12 FUT3 FUT6 NOS2	1.01e-04	196	105	5	91a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMPRSS4 CYP4F12 FUT3 FUT6 NOS2	1.01e-04	196	105	5	e819088a74d29e958371aa851ac9c74ec55367b7
ToppCell	BAL-Mild-Epithelial-Epithelial-Basal/Club\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	TMPRSS4 CYP4F12 FUT3 FUT6 NOS2	1.01e-04	196	105	5	e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCell	3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMPRSS4 SYT8 PKP3 CYP4F12 NOS2	1.01e-04	196	105	5	8e96fc87812d112ccae6e2ca1821bee1ee2efe48
ToppCell	distal-Epithelial-Goblet\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMPRSS4 ILDR1 CYP4F12 FUT3 FUT6	1.04e-04	197	105	5	da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCell	COVID-19-Epithelial-Club,_Basal_cells\|Epithelial / Condition, Lineage and Cell class	CYP24A1 TMPRSS4 EGFL6 NYNRIN FUT6	1.04e-04	197	105	5	78ed2810e5a765327e7a6da0ca5d4854bf7a0b6f
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-epithelial_progenitor_cell-TA\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMPRSS4 NOX1 PKP3 FUT3 NOS2	1.04e-04	197	105	5	9ae6d987e65972e1fb21aa407788d5e3ff41ad64
ToppCell	Mild_COVID-19-Epithelial-Basal/Club\|Mild_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TMPRSS4 CYP4F12 FUT3 FUT6 NOS2	1.04e-04	197	105	5	4cc5b778e1e2c6c149160fa147c172977c0fa8eb
ToppCell	distal-Epithelial-Goblet-3\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	TMPRSS4 ILDR1 CYP4F12 FUT3 FUT6	1.04e-04	197	105	5	3fbf456ae4f73da4f6254a6f0d24f0ec27d7a3cc
ToppCell	Epithelial_cells-Basal_cells\|Epithelial_cells / lung cells shred on cell class, cell subclass, sample id	CYP24A1 TMPRSS4 ITGB4 SYT8 NYNRIN	1.06e-04	198	105	5	4235005c49fc2b29ad3a0ee6b608f0109d04f775
ToppCell	medial-Epithelial-Basal\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.09e-04	199	105	5	fa7584e3cc0f8cbdd6a76c6a0faee26b0922c4ae
ToppCell	BAL-Severe-Epithelial-Epithelial-Basal/Club\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMPRSS4 ITGB4 PKP3 FUT3 FUT6	1.09e-04	199	105	5	d04062d86643e5712cc2f519f4f36e643d404a16
ToppCell	medial-Epithelial-Basal-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.09e-04	199	105	5	fc37f8868417308fb4410684d0d1e506cec30f35
ToppCell	medial-2-Epithelial-Basal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.09e-04	199	105	5	10af93596cc6d5da4cf5052707ff5f7fc347dc84
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_airway_secretory-Secretory_Goblet\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	TMPRSS4 CYP4F12 FUT3 FUT6 NOS2	1.09e-04	199	105	5	3c3133d0aa65338a576634def13e7f0f5c573a10
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TMPRSS4 ITGB4 SYT8 PKP3 CYP4F12	1.09e-04	199	105	5	ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell	Biopsy_IPF-Epithelial-MUC5AC+_High\|Biopsy_IPF / Sample group, Lineage and Cell type	CYP24A1 TMPRSS4 CYP4F12 FUT3 FUT6	1.09e-04	199	105	5	51cb306e36537a53968c55187bd87c83e1706187
ToppCell	Severe_COVID-19-Epithelial-Basal/Club\|Severe_COVID-19 / Disease group,lineage and cell class （2021.01.30）	TMPRSS4 ITGB4 PKP3 FUT3 FUT6	1.09e-04	199	105	5	2a0aebcfadff4e2dfc8244ad8a87c338ecccacfd
ToppCell	BAL-Severe-Epithelial-Epithelial-Basal/Club-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	TMPRSS4 ITGB4 PKP3 FUT3 FUT6	1.09e-04	199	105	5	fd364f43859b2e7a3e91ce6a1c430cc42ad26a49
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	afac850d5a40de0d6f02857cf81a19443d90b1eb
ToppCell	Parenchyma_COVID-19-Epithelial-TX-Basal_1\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	592c7c3ded409a9957cbcdc62fcc213fa8eae598
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THEMIS2 HLA-DMA PTGS1 SH3TC1 ALPK3	1.11e-04	200	105	5	80e0483d5ab0c6213aae0ec62619f57e6ec0e4c2
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	8cfbde43c5e66269ad128aa5398b1517667d7d36
ToppCell	distal-Epithelial-Basal\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	5c14f0c09bb8b3daf6d649032e888a7880c52b73
ToppCell	distal-Epithelial-Basal-2\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	6f00d08e93f89b3575ebbd5c2f451e655d449ef3
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	THEMIS2 HLA-DMA PTGS1 SH3TC1 ALPK3	1.11e-04	200	105	5	74ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Basal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	0594ca7bc313b73e1dc800cf058f8f798b0284cb
ToppCell	distal-2-Epithelial-Basal\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	9beb128841c50241aa819261f21bf66f881ea125
ToppCell	Lung_Parenchyma-Severe-Epithelial-Epithelial-Basal_1\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CYP24A1 TMPRSS4 ITGB4 SYT8 PKP3	1.11e-04	200	105	5	61811380d9252f12f27b7ad4752380b52692677f
Drug	AC1MPID6	FUT3 FUT4 FUT5 FUT6 FUT7	1.03e-11	6	103	5	CID003411618
Drug	AC1MQWF5	FUT3 FUT4 FUT5 FUT6 FUT7	4.25e-10	10	103	5	CID003458642
Drug	AC1MPID3	FUT3 FUT4 FUT5 FUT6 FUT7	1.90e-08	19	103	5	CID003411617
Drug	(2S,3R,4S,5S,6R)-2-benzyl-6-(hydroxymethyl)oxane-3,4,5-triol	FUT3 FUT4 FUT5 FUT6 FUT7	5.42e-08	23	103	5	CID010332525
Drug	2'-fucosyllactose	FUT3 FUT4 FUT5 FUT6 FUT7	2.24e-07	30	103	5	CID000170484
Drug	lacto-N-tetraose	FUT3 FUT4 FUT5 FUT6 FUT7	3.14e-07	32	103	5	CID000440993
Drug	NSC638615	CYP21A2 PTGS1 FUT3 FUT4 FUT5 FUT6 FUT7	5.68e-07	107	103	7	CID000097535
Drug	NSC35456	STRBP PIGZ TMEM121 PIGF NOS2	1.82e-06	45	103	5	CID000006725
Drug	diosmetin	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12 NOS2	2.42e-06	85	103	6	CID005281612
Drug	AC1Q5O3K	FUT3 FUT4 FUT5 FUT6 FUT7	2.80e-06	49	103	5	CID000001529
Drug	AC1L2R6I	CYP21A2 FUT3 FUT6 FUT7	7.44e-06	28	103	4	CID000126931
Drug	(Z)-7-[(1S,4R,6R)-5-[(E)-oct-1-enyl]-2,3-diazabicyclo[2.2.1]hept-2-en-6-yl]hept-5-enoic acid	CYP4F8 PTGS1 CYP4F12	1.05e-05	10	103	3	CID009905657
Drug	aminopyrine	CYP4F8 HLA-DMA CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12	1.29e-05	171	103	7	CID000006009
Drug	propoxyphene	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.33e-05	67	103	5	CID000010100
Drug	GDP-fucose	FUT3 FUT4 FUT5 FUT6 FUT7	1.43e-05	68	103	5	CID000000451
Drug	carteolol	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.89e-05	72	103	5	CID000002583
Drug	sLex	FUT3 FUT4 FUT5 FUT6 FUT7	1.89e-05	72	103	5	CID004564901
Drug	82570-34-1	PTGS1 NOS2	2.03e-05	2	103	2	CID000174280
Drug	azo analog I	CYP4F8 PTGS1 CYP4F12	2.49e-05	13	103	3	CID006438575
Drug	chloral hydrate	CYP4F8 CYP21A2 CYP24A1 CYP51A1 SLC17A5 CYP4F12	2.68e-05	129	103	6	CID000002707
Drug	sLea	FUT3 FUT4 FUT5 FUT6 FUT7	2.79e-05	78	103	5	CID000643993
Drug	Prednisone [53-03-2]; Down 200; 11.2uM; MCF7; HT_HG-U133A	ING1 XYLT2 NOX1 PKP3 C1orf159 RHBDD3 RUSF1	3.00e-05	195	103	7	1478_DN
Drug	ST021200; Up 200; 10uM; PC3; HT_HG-U133A	JCAD ITGB4 RTN2 XYLT2 C1orf159 FUT3 IL27RA	3.00e-05	195	103	7	7559_UP
Drug	Doxylamine succinate [562-10-7]; Down 200; 10.2uM; PC3; HT_HG-U133A	PXMP4 ITGB4 TBC1D17 PKP3 ERI3 FUT6 PLXNB1	3.00e-05	195	103	7	4235_DN
Drug	PNU-0230031 [267429-39-0]; Down 200; 10uM; PC3; HT_HG-U133A	PXMP4 THEMIS2 ITGA2B LCAT ITGB4 SH3TC1 PKP3	3.00e-05	195	103	7	3732_DN
Drug	trimipramine	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	3.16e-05	80	103	5	CID000005584
Drug	3'-sialyl LewisX	OSTM1 TRRAP FUT3 FUT4 FUT5 FUT6 FUT7	3.21e-05	197	103	7	CID000643990
Drug	Gentamicine sulfate [1405-41-0]; Up 200; 2.6uM; PC3; HT_HG-U133A	TMPRSS4 TMEM121 CNPPD1 SLC17A5 PKP3 FUT3 FUT6	3.21e-05	197	103	7	5883_UP
Drug	Serotonin hydrochloride [153-98-0]; Down 200; 18.8uM; HL60; HT_HG-U133A	SLC4A7 ING1 ACP3 ITGB4 NMT2 RUSF1 IL27RA	3.42e-05	199	103	7	2449_DN
Drug	Benoxinate hydrochloride [5987-82-6]; Up 200; 11.6uM; MCF7; HT_HG-U133A	SLC6A16 ACP3 HIPK2 ITGB4 NOX1 CYP4F12 FUT7	3.42e-05	199	103	7	4115_UP
Drug	estradiol, USP; Down 200; 0.01uM; MCF7; HT_HG-U133A	ING1 ITGB4 TMEM121 TBC1D17 SLC17A5 PKP3 PLXNB1	3.53e-05	200	103	7	1666_DN
Drug	3'SLN	FUT3 FUT4 FUT7	3.93e-05	15	103	3	CID000643986
Drug	GDP-Man	PIGZ FUT3 FUT4 FUT5 FUT6 FUT7	4.25e-05	140	103	6	CID000000732
Drug	2a-e	FUT3 FUT5 FUT6 FUT7	4.26e-05	43	103	4	CID000006942
Drug	diclofenac	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12 NOS2	4.67e-05	209	103	7	CID000003032
Drug	mephenytoin	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	5.00e-05	88	103	5	CID000004060
Drug	lacto-N-neotetraose	FUT3 FUT4 FUT5 FUT6	5.57e-05	46	103	4	CID000121853
Drug	camonagrel	ITGA2B PTGS1 NOS2	5.84e-05	17	103	3	CID000065892
Drug	tienilic acid	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	6.51e-05	93	103	5	CID000038409
Drug	lansoprazole	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	6.51e-05	93	103	5	CID000003883
Drug	AC1L1KIN	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	9.20e-05	100	103	5	CID000005516
Drug	Sparteinum	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	9.65e-05	101	103	5	CID000003966
Drug	N-acetyllactosamine	XYLT2 FUT3 FUT4 FUT5 FUT6 FUT7	1.02e-04	164	103	6	CID000000245
Drug	Hawleyite	ACP3 PTGS1	1.21e-04	4	103	2	CID009793819
Drug	Triflusal	PTGS1 NOS2	1.21e-04	4	103	2	DB08814
Drug	K-K-K	CYP21A2 CYP24A1 CYP51A1 CYP4F12 NOS2 IL27RA	1.46e-04	175	103	6	CID000003823
Drug	miconazole	CYP21A2 CYP51A1 PTGS1 NOS2	1.48e-04	59	103	4	CID000004189
Drug	metyrapone	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 CYP4F12	1.65e-04	179	103	6	CID000004174
Drug	Methotrexate [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A	TMEM121 TBC1D17 NOX1 C1orf159 FUT4 PLXNB1	1.75e-04	181	103	6	5419_DN
Drug	dioxin	CYP4F8 CYP21A2 CYP24A1 CYP51A1 PTGS1 NMT2 CYP4F12 NOS2	1.82e-04	347	103	8	CID000015625
Drug	AC1Q7AUJ	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	1.93e-04	117	103	5	CID000003303
Drug	8-MOP	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	2.01e-04	118	103	5	CID000004114
Drug	isomallotochromanol	PTGS1 NOS2	2.01e-04	5	103	2	CID000159574
Drug	loxoprofen	PTGS1 NOS2	2.01e-04	5	103	2	ctd:C040656
Drug	4-(nitroxy)butanoic acid 4-acetylaminophenyl ester	PTGS1 NOS2	2.01e-04	5	103	2	ctd:C478738
Drug	Metixene hydrochloride [1553-34-0]; Up 200; 11.6uM; PC3; HT_HG-U133A	SLC4A7 SLC6A16 ACP3 ITGA2B SLC17A5 FUT6	2.03e-04	186	103	6	6672_UP
Drug	Miconazole	CYP51A1 PTGS1 NOX1 NOS2	2.16e-04	65	103	4	ctd:D008825
Drug	Industrial Waste	CYP21A2 CYP51A1 NOS2	2.17e-04	26	103	3	ctd:D007220
Drug	pioglitazone HCl; Up 200; 10uM; MCF7; HT_HG-U133A	SLC4A7 ING1 RTN2 PCNX4 ERMAP RHBDD3	2.41e-04	192	103	6	6898_UP
Drug	alprazolam	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12 CDH8	2.48e-04	193	103	6	CID000002118
Drug	Clotrimazole [23593-75-1]; Down 200; 11.6uM; PC3; HT_HG-U133A	HIPK2 PIGZ ITGB4 PKP3 RHBDD3 IL27RA	2.48e-04	193	103	6	5726_DN
Drug	Podophyllotoxin [518-28-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A	THEMIS2 JCAD HIPK2 RTN2 CYP4F12 FUT7	2.48e-04	193	103	6	6103_UP
Drug	Theobromine [83-67-0]; Down 200; 22.2uM; PC3; HT_HG-U133A	JCAD ITGA2B ITGB4 TBC1D17 ERMAP RHBDD3	2.48e-04	193	103	6	6613_DN
Drug	Tocainide hydrochloride; Up 200; 17.4uM; MCF7; HT_HG-U133A	ILF3 TRRAP ITGB4 PTGS1 TBC1D17 SH3TC1	2.55e-04	194	103	6	4838_UP
Drug	0317956-0000 [391210-11-0]; Down 200; 10uM; PC3; HT_HG-U133A	ITGB4 CNPPD1 NOX1 PKP3 RHBDD3 PLXNB1	2.55e-04	194	103	6	4331_DN
Drug	NS-398; Up 200; 10uM; MCF7; HT_HG-U133A	TOR1AIP2 SLC4A7 ING1 ITGB4 SLC22A4 ERMAP	2.55e-04	194	103	6	6897_UP
Drug	Thalidomide [50-35-1]; Up 200; 15.4uM; MCF7; HT_HG-U133A	ACP3 HIPK2 ITGA2B SLC22A7 NYNRIN FUT6	2.55e-04	194	103	6	2258_UP
Drug	Aztreonam [78110-38-0]; Down 200; 9.2uM; PC3; HT_HG-U133A	TBC1D17 XYLT2 SLC17A5 SLC22A4 C1orf159 FUT4	2.55e-04	194	103	6	2118_DN
Drug	Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; PC3; HT_HG-U133A	PXMP4 XYLT2 SH3TC1 PKP3 ALPK3 FUT6	2.62e-04	195	103	6	3695_DN
Drug	Fenoprofen calcium salt dihydrate [53746-45-5]; Up 200; 7.2uM; MCF7; HT_HG-U133A	TMPRSS4 PTGS1 BRINP2 RHBDD3 FUT6 CDH8	2.62e-04	195	103	6	4736_UP
Drug	Prilocaine hydrochloride [1786-81-8]; Up 200; 15.6uM; HL60; HT_HG-U133A	HIPK2 PRSS21 CYP4F12 FUT6 RUSF1 IL27RA	2.70e-04	196	103	6	2352_UP
Drug	Sulfadoxine [2447-57-6]; Up 200; 12.8uM; PC3; HT_HG-U133A	ACP3 RTN2 TBC1D17 SLC17A5 NMT2 FUT6	2.70e-04	196	103	6	5852_UP
Drug	Decamethonium bromide [541-22-0]; Down 200; 9.6uM; MCF7; HT_HG-U133A	ING1 PIGZ TBC1D17 NOX1 RHBDD3 FHIP2B	2.70e-04	196	103	6	7353_DN
Drug	Ramipril [87333-19-5]; Up 200; 9.6uM; MCF7; HT_HG-U133A	ING1 ACP3 HIPK2 PTGS1 RHBDD3 CYP4F12	2.70e-04	196	103	6	3572_UP
Drug	Sulfamonomethoxine [1220-83-3]; Up 200; 14.2uM; HL60; HT_HG-U133A	CYP4F8 TRPC4 TMPRSS4 ITGB4 SLC22A7 PKP3	2.70e-04	196	103	6	2742_UP
Drug	Parbendazole [14255-87-9]; Up 200; 16.2uM; MCF7; HT_HG-U133A	CYP24A1 TMPRSS4 ITGA2B SLC22A7 NOX1 FUT7	2.77e-04	197	103	6	3881_UP
Drug	Estropipate [7280-37-7]; Up 200; 9.2uM; MCF7; HT_HG-U133A	THEMIS2 JCAD TMPRSS4 SLC22A4 FUT6 FUT7	2.77e-04	197	103	6	6068_UP
Drug	Ifosfamide [3778-73-2]; Down 200; 15.4uM; PC3; HT_HG-U133A	PXMP4 PIGZ RTN2 TMEM121 TBC1D17 SLC22A4	2.77e-04	197	103	6	5805_DN
Drug	C75; Up 200; 10uM; PC3; HT_HG-U133A	SH3TC1 BRINP2 RHBDD3 FUT6 FUT7 NOS2	2.77e-04	197	103	6	6399_UP
Drug	hexobarbital	CYP4F8 CYP21A2 CYP24A1 CYP51A1 CYP4F12	2.82e-04	127	103	5	CID000003608
Drug	Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; MCF7; HT_HG-U133A	ACP3 ITGA2B PTGS1 NOX1 RHBDD3 CYP4F12	2.85e-04	198	103	6	2288_UP
Drug	Clebopride maleate [84370-95-6]; Down 200; 8.2uM; MCF7; HT_HG-U133A	ING1 ITGB4 RTN2 NOX1 ERMAP C1orf159	2.85e-04	198	103	6	5412_DN
Drug	Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; HL60; HT_HG-U133A	SLC4A7 ITGB4 NOX1 PRSS21 RHBDD3 FUT6	2.85e-04	198	103	6	2542_DN
Drug	Lithocholic acid [434-13-9]; Down 200; 10.6uM; PC3; HT_HG-U133A	ING1 XYLT2 RHBDD3 FUT4 FUT6 PLXNB1	2.85e-04	198	103	6	4551_DN
Drug	Mifepristone [84371-65-3]; Up 200; 9.4uM; MCF7; HT_HG-U133A	SLC6A16 GRM6 SLC22A7 C1orf159 RHBDD3 FUT6	2.85e-04	198	103	6	3185_UP
Drug	Iproniazide phosphate [305-33-9]; Up 200; 14.4uM; PC3; HT_HG-U133A	PXMP4 JCAD PKP3 RHBDD3 FUT6 FUT7	2.85e-04	198	103	6	2125_UP
Drug	Thiocolchicoside [602-41-5]; Up 200; 7uM; MCF7; HT_HG-U133A	CYP4F8 ITGB4 TBC1D17 C1orf159 RHBDD3 CYP4F12	2.85e-04	198	103	6	5520_UP
Drug	Sulfamerazine [127-79-7]; Up 200; 15.2uM; MCF7; HT_HG-U133A	CYP24A1 HIPK2 RTN2 SLC22A7 PRSS21 FUT6	2.85e-04	198	103	6	6036_UP
Drug	Nalidixic acid sodium salt hydrate; Down 200; 14.6uM; PC3; HT_HG-U133A	ING1 ITGA2B ITGB4 SH3TC1 RHBDD3 FUT6	2.93e-04	199	103	6	3668_DN
Drug	Trimethylcolchicinic acid [3482-37-9]; Down 200; 11.6uM; MCF7; HT_HG-U133A	TOR1AIP2 ING1 TRRAP ITGB4 NMT2 ERMAP	2.93e-04	199	103	6	2802_DN
Drug	Bemegride [64-65-3]; Up 200; 25.8uM; MCF7; HT_HG-U133A	JCAD HIPK2 CNPPD1 NOX1 CYP4F12 CDH8	2.93e-04	199	103	6	3389_UP
Drug	Clofilium tosylate [92953-10-1]; Down 200; 7.8uM; MCF7; HT_HG-U133A	ING1 TMEM121 SLC22A4 PLXNB1 MTMR9 IL27RA	2.93e-04	199	103	6	6830_DN
Drug	ruban	CYP24A1 FUT3	3.00e-04	6	103	2	CID000087176
Drug	fructose-1,6-diphosphate	PTGS1 NOS2	3.00e-04	6	103	2	ctd:C029063
Drug	ethyl 3-(3,4-dihydroxyphenyl)acrylate	PTGS1 NOS2	3.00e-04	6	103	2	CID000066883
Drug	rossicaside B	NOX1 NOS2	3.00e-04	6	103	2	ctd:C547390
Drug	cyclolinteinone	PTGS1 NOS2	3.00e-04	6	103	2	CID006444308
Drug	Decamethonium bromide [541-22-0]; Up 200; 9.6uM; PC3; HT_HG-U133A	SLC6A16 TMPRSS4 ITGB4 PTGS1 BRINP2 FUT6	3.01e-04	200	103	6	4094_UP
Drug	AC1L1F9Q	CYP4F8 LCAT PTGS1 NPHP3 CYP4F12 NOS2	3.09e-04	201	103	6	CID000003144
Disease	alpha-(1;3)-fucosyltransferase 5 measurement	FUT3 FUT5 FUT6	1.42e-07	4	98	3	EFO_0021979
Disease	candidiasis (implicated_via_orthology)	FUT3 FUT4 FUT5 FUT6 FUT7	3.57e-07	44	98	5	DOID:1508 (implicated_via_orthology)
Disease	galactoside 3(4)-L-fucosyltransferase measurement	FUT3 FUT5 FUT6	1.23e-06	7	98	3	EFO_0021853
Disease	alpha-(1,3)-fucosyltransferase 5 measurement	FUT3 FUT5 FUT6	1.23e-06	7	98	3	EFO_0020136
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	1.09e-05	2	98	2	DOID:0110471 (implicated_via_orthology)
Disease	carbohydrate measurement	HIPK2 ANTXR2 FUT3 FUT6	1.68e-05	46	98	4	EFO_0004998
Disease	serum carcinoembryonic antigen measurement	FUT3 FUT5 FUT6	3.89e-05	20	98	3	EFO_0005760
Disease	cancer antigen 19.9 measurement	FUT3 FUT6	6.52e-05	4	98	2	EFO_0010584
Disease	polyp of gallbladder	FUT3 FUT6	6.52e-05	4	98	2	MONDO_0021416
Disease	lymphocyte count	THEMIS2 JCAD SLC4A7 STRBP CYP21A2 ERVW-1 ZNF295-AS1 ZNF469 ANTXR2 PKP3 SLC22A4 ILDR1 FUT7 FAM177A1 IL27RA	9.55e-05	1464	98	15	EFO_0004587
Disease	desmoglein-2 measurement	FUT3 FUT6	1.08e-04	5	98	2	EFO_0020322
Disease	level of V-set and immunoglobulin domain-containing protein 2 in blood serum	FUT3 FUT6	1.08e-04	5	98	2	OBA_2044774
Disease	Endometrial Stromal Sarcoma	NUTM2A NUTM2B	1.08e-04	5	98	2	C0206630
Disease	Clear cell sarcoma of kidney	NUTM2E NUTM2B	1.62e-04	6	98	2	C0334488
Disease	lactoperoxidase measurement	FUT3 FUT6	1.62e-04	6	98	2	EFO_0020525
Disease	urinary potassium to creatinine ratio	SLC4A7 CYP21A2	1.62e-04	6	98	2	EFO_0009882
Disease	Ovarian Cysts	PTGS1 IARS2 NMT2	2.15e-04	35	98	3	C0029927
Disease	Corpus Luteum Cyst	PTGS1 IARS2 NMT2	2.15e-04	35	98	3	C0010093
Disease	lithostathine-1-alpha measurement	FUT3 FUT6	2.27e-04	7	98	2	EFO_0801083
Disease	Alzheimer's disease (implicated_via_orthology)	CYP51A1 PTGS1 NOS2	9.13e-04	57	98	3	DOID:10652 (implicated_via_orthology)
Disease	cancer biomarker measurement	FUT3 FUT6	1.11e-03	15	98	2	EFO_0005127
Disease	anemia (implicated_via_orthology)	SLC4A7 SLC4A10	1.11e-03	15	98	2	DOID:2355 (implicated_via_orthology)
Disease	calcium measurement	CYP21A2 CYP24A1 TMEM121 PCNX4 NYNRIN ILDR1 ASCC3 FHIP2B	1.18e-03	628	98	8	EFO_0004838
Disease	galectin-3 measurement	FUT3 FUT6	1.27e-03	16	98	2	EFO_0008137
Disease	Gastric ulcer	PTGS1 NOS2	1.61e-03	18	98	2	C0038358
Disease	bipolar disorder, schizophrenia, response to lithium ion	HLA-DMA FAM177A1	2.00e-03	20	98	2	GO_0010226, MONDO_0004985, MONDO_0005090
Disease	axial length measurement	PRSS56 PIGZ ZNF469	2.17e-03	77	98	3	EFO_0005318
Disease	N-glycan measurement	FUT3 FUT6	2.42e-03	22	98	2	EFO_0004999
Disease	e-selectin measurement	FUT3 FUT6	2.42e-03	22	98	2	EFO_0004575
Disease	Ureteral obstruction	HIPK2 NOS2	2.87e-03	24	98	2	C0041956
Disease	Malignant neoplasm of breast	THEMIS2 STRBP CYP24A1 TRPC4 GRM6 PKDREJ PTGS1 NOS2 RUSF1 PLXNB1	3.03e-03	1074	98	10	C0006142
Disease	colon adenocarcinoma (is_marker_for)	CYP24A1 NOS2	3.12e-03	25	98	2	DOID:234 (is_marker_for)
Disease	cholelithiasis	CYP21A2 FUT3 FUT6	3.18e-03	88	98	3	EFO_0004799

Protein segments in the cluster

Peptide	Gene	Start	Entry
WEGGLVSWPPAPPLT	ERI3	16	O43414
MPLPWSLALPLLLSW	EGFL6	1	Q8IUX8
WMSWVLPILSPLIPI	nan	511	Q9N2J8
LVLWLPGLPRSSPSW	ALPK3	31	Q96L96
PPPLALPLHLGGWWV	APCDD1L	271	Q8NCL9
PGSWLFPGLWLLVLS	ANTXR2	11	P58335
GLWPWVLGLLSLPGV	ASTL	6	Q6HA08
WIWLVPPMSGSITPV	NOS2	461	P35228
PPESWKWILAPVILY	NOX1	266	Q9Y5S8
SLVLPWSFPLEWAPQ	TOR1AIP2	61	Q9H496
WALALGLVLLLPPWA	GPR88	166	Q9GZN0
AWPSGTQQILLPPAW	HIPK2	706	Q9H2X6
PEFLLWALRPPGWLL	NMT2	196	O60551
PTVDPTKLTWGPYLW	FAM177A1	86	Q8N128
VIWPSVAPQSLPLWE	MTMR9	481	Q96QG7
ASPTPSRPVGVLLWW	FUT4	181	P22083
VLADSSPRWLWGQPP	JCAD	491	Q9P266
LPLPQPAQSWVWLVD	HERC1	1126	Q15751
WWKLRSLHLPPLAPG	CYP21A2	21	P08686
WALGTLPPPDALLLW	PCNX4	256	Q63HM2
GWVLPPLPSNDIWAT	PDCD7	466	Q8N8D1
ALWAGWVLTLQPLPP	PLXNB1	11	O43157
RVASWGWPLTPTPLD	FHIP2B	576	Q86V87
LLLCWLAAPWPTQPE	MMP21	11	Q8N119
PGLSGAPSWWTLPLI	OR51S1	26	Q8NGJ8
WLSLPGLPPGWALFA	PPM1N	86	Q8N819
PAPQPTITILVWHWP	FUT7	41	Q11130
LPAPWLLLCTWLPAG	ILDR1	6	Q86SU0
GAPFWLWPLPKLALL	IL27RA	6	Q6UWB1
LWGEWSPILSFQTPP	IL27RA	216	Q6UWB1
TLPDLPWGPCELWVT	IL27RA	476	Q6UWB1
PWVVATSVPLFWPLN	GPR101	86	Q96P66
PWLPLGLLLWSGLAL	OSTM1	16	Q86WC4
PGLWTWLRNSLRPSP	PTGS1	71	P23219
CPPGSFWWLIPLLLL	ITGB4	706	P16144
PEGVSIWNPILLWQP	ACP3	126	P15309
YGLAPPWPWSPVLLS	CNPPD1	371	Q9BV87
WLWGAQPCLLLPIVP	ADAMTS4	16	O75173
VVRLSWSSPWAAPPL	GRM6	576	O15303
WSSPWAAPPLLLAVL	GRM6	581	O15303
LSPRPPLGSSLSPWW	KDM2B	831	Q8NHM5
PTSWPLLGSLLQILW	CYP24A1	61	Q07973
EAGDLPVLLWWSPGL	FUT11	71	Q495W5
LSWLGLRPVAASPWL	CYP4F8	6	P98187
LPWLGLRPVATSPWL	CYP4F12	6	Q9HCS2
SHAAWLLPGWLPLPS	CYP51A1	241	Q16850
PTWGPLRGWPLELLC	ILF3	241	Q12906
PLLWLLPHSWAVPEA	HLA-DMA	16	P28067
PFLPEALLTVWWLPF	CYP4F30P	96	Q9H0H9
TPAHSIPLILLWTWP	FUT6	56	P51993
IPLILLWTWPFNKPI	FUT6	61	P51993
SPWQWVTLLLGLLLP	LCAT	6	P04180
DLWTPLIILWITLPP	CDH8	11	P55286
SLWIPPTSRHPPTLW	FAM186A	1921	A6NE01
PVHLLGPPSSRWALW	GPR146	81	Q96CH1
GRIWLVPPALDLSWI	C1orf159	256	Q96HA4
LPCAPGILSLWWVPE	SLC22A7	266	Q9Y694
PWVPILKSLPLWAIV	SLC17A5	281	Q9NRA2
PGVLCVPLWWFIPES	SLC22A4	266	Q9H015
APPGAWPWLVRLQLG	PRSS56	111	P0CW18
LRWGPAPLLTPRGIW	NYNRIN	141	Q9P2P1
LTPGRAQLLWSPWSP	INCA1	181	Q0VD86
LLPWWLPQSPVPASG	NUTM2A	771	Q8IVF1
LLPWWLPQSPVPASG	NUTM2B	771	A6NNL0
PWWLPQSPVPASGLL	NUTM2D	701	Q5VT03
LLPWWLPQSPVPASG	NUTM2E	771	B1AL46
PLSLWPGTVPKEVRW	ERMAP	51	Q96PL5
PTLLILLWTWPFHIP	FUT3	61	P21217
PAHPTLLILLWTWPF	FUT5	71	Q11128
PLWTGFWPAPSLSLG	RUSF1	316	Q96GQ5
PILELSPPLWTAIGW	RTN2	291	O75298
LIPDLVAGTPWPRWA	SYT8	36	Q8NBV8
KWPLWLSPFQVVVIP	TARS2	606	Q9BW92
FPGWVPWLLLGSVLI	TAS2R41	126	P59536
LSQWMPWILPFLGPL	ERVW-1	441	Q9UQF0
LLGHPISPIFGWLWP	SLC6A16	601	Q9GZN6
PERGWIISPLGDNPW	SLC4A7	896	Q9Y6M7
IISPLGDNPWWTLLI	SLC4A7	901	Q9Y6M7
WRLWPTLHLDPLSPK	NPHP3	661	Q7Z494
AWLGALPIPLDWERP	PIGF	166	Q07326
WLEAWRVSPLPLSPL	ING1	116	Q9UK53
LKWPWASGPVLTLLP	PKDREJ	406	Q9NTG1
VNLPPLPLCGWAPWL	SH3TC1	1316	Q8TE82
RVPTWAPLKGWPLEL	STRBP	231	Q96SI9
GSDIWWTLPPEQLLP	IARS2	561	Q9NSE4
WVLLLLGPCAAPPAW	ITGA2B	16	P08514
AWPQELLWAVLPLLP	STRC	861	Q7RTU9
VAPWTALLALGLPGW	BRINP2	16	Q9C0B6
WGWASPLRQFSILPP	ASCC3	1121	Q8N3C0
GALPPWLSPWLLLAL	RHBDD3	141	Q9Y3P4
PKGLEWLWSPQIVGL	PKP3	596	Q9Y446
RLWEVLWTGLPGPNL	TBC1D17	511	Q9HA65
LVPWLLLGASWLIPQ	RHBDD2	166	Q6NTF9
SLWEPPRSGLPLWAE	TMEM121	166	Q9BTD3
PFWTWEPSAPRTLLQ	THEMIS2	166	Q5TEJ8
LGPNPWWTVIAAIIP	SLC4A10	806	Q6U841
EELTPATPLWIIGWG	TMPRSS4	316	Q9NRS4
LLRLWEELGPWPGLV	PIGZ	106	Q86VD9
SLPSWLPGLPSLEWG	TMEM82	6	A0PJX8
PGIDPWAPGLSLWAL	ZNF469	2921	Q96JG9
AWPQELLWAVLPLLP	STRCP1	861	A6NGW2
SWPLLFFPLLWALPL	PRSS21	296	Q9Y6M0
LLAPPSSSWTLWVAP	ZNF295-AS1	36	Q8N0V1
AGPVRPELWLLLWAA	SLIT1	11	O75093
PRWDPFPLLTAVVWG	PXMP4	151	Q9Y6I8
VPPIQWLAWIPQLLT	TRRAP	3226	Q9Y4A5
PLRPGPWTVRLLQFW	XYLT2	721	Q9H1B5
GPPPTIVEWMILPWV	TRPC4	396	Q9UBN4
WPPHPLQIVAWLLYL	ZDHHC1	46	Q8WTX9
ALGPRNPWTLWTPLT	ZNF296	81	Q8WUU4
MGLPVSWAPPALWVL	LIME1	1	Q9H400