Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyCellularComponentmicrotubule plus-end

GAS2L2 NUMA1 NCKAP5L

1.31e-0428743GO:0035371
GeneOntologyCellularComponentmicrotubule end

GAS2L2 NUMA1 NCKAP5L

3.29e-0438743GO:1990752
HumanPhenoAbnormality of the pineal gland

FLII INSR RAI1

8.72e-0520233HP:0012680
HumanPhenoShort REM sleep

FLII RAI1

1.16e-044232HP:5200360
HumanPhenoAbnormal sleep architecture

FLII RAI1

1.16e-044232HP:5200298
HumanPhenoOnychotillomania

FLII RAI1

1.16e-044232HP:0032509
HumanPhenoVocal cord polyp

FLII RAI1

1.16e-044232HP:0032041
DomainTF_AP2

TFAP2D TFAP2E TFAP2A TFAP2B

1.07e-095734IPR004979
DomainTF_AP2_C

TFAP2D TFAP2E TFAP2A TFAP2B

1.07e-095734IPR013854
DomainTF_AP-2

TFAP2D TFAP2E TFAP2A TFAP2B

1.07e-095734PF03299
DomainSBF2

KIAA0513 SBF2

4.51e-053732PF12335
DomainSBF1/SBF2

KIAA0513 SBF2

4.51e-053732IPR022096
DomainRNase_Zc3h12a

ZC3H12A ZC3H12C

3.12e-047732PF11977
DomainRNase_Zc3h12_NYN

ZC3H12A ZC3H12C

3.12e-047732IPR021869
PathwayREACTOME_NEGATIVE_REGULATION_OF_ACTIVITY_OF_TFAP2_AP_2_FAMILY_TRANSCRIPTION_FACTORS

TFAP2D TFAP2E TFAP2A TFAP2B

2.05e-089524MM15509
PathwayREACTOME_NEGATIVE_REGULATION_OF_ACTIVITY_OF_TFAP2_AP_2_FAMILY_TRANSCRIPTION_FACTORS

TFAP2D TFAP2E TFAP2A TFAP2B

3.40e-0810524M27764
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

TFAP2D TFAP2E TFAP2A TFAP2B

5.33e-0811524MM15510
PathwayREACTOME_ACTIVATION_OF_THE_TFAP2_AP_2_FAMILY_OF_TRANSCRIPTION_FACTORS

TFAP2D TFAP2E TFAP2A TFAP2B

7.97e-0812524M27765
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

TFAP2D TFAP2E TFAP2A TFAP2B

2.32e-0626524MM15502
PathwayREACTOME_TRANSCRIPTIONAL_REGULATION_BY_THE_AP_2_TFAP2_FAMILY_OF_TRANSCRIPTION_FACTORS

TFAP2D TFAP2E TFAP2A TFAP2B

1.11e-0538524M27757
PathwayWP_INSULIN_SIGNALING_IN_ADIPOCYTES_NORMAL_CONDITION

RPS6KB1 INSR

3.68e-048522M39447
PathwayWP_INSULIN_SIGNALING_IN_ADIPOCYTES_DIABETIC_CONDITION

RPS6KB1 INSR

3.68e-048522M39537
Pubmed

Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup development.

TFAP2D TFAP2E MKI67 TFAP2A TFAP2B

5.17e-111375517724084
Pubmed

Analysis of transcription factor AP-2 expression and function during mouse preimplantation development.

TFAP2D TFAP2E TFAP2A TFAP2B

9.95e-11575416672719
Pubmed

AP-2α and AP-2β regulate dorsal interneuron specification in the spinal cord.

TFAP2D TFAP2E TFAP2A TFAP2B

9.95e-11575427984181
Pubmed

Cloning and characterization of the mouse AP-2 epsilon gene: a novel family member expressed in the developing olfactory bulb.

TFAP2D TFAP2E TFAP2A TFAP2B

6.95e-10775414572467
Pubmed

AP-2ε Expression in Developing Retina: Contributing to the Molecular Diversity of Amacrine Cells.

TFAP2D TFAP2E TFAP2A TFAP2B

6.95e-10775429467543
Pubmed

AP2gamma regulates basal progenitor fate in a region- and layer-specific manner in the developing cortex.

TFAP2D TFAP2E MKI67 TFAP2A TFAP2B

2.59e-092675519749747
Pubmed

Expression of Tfap2d, the gene encoding the transcription factor Ap-2 delta, during mouse embryogenesis.

TFAP2D TFAP2A TFAP2B

3.85e-08475312711551
Pubmed

Loss of AP-2delta reduces retinal ganglion cell numbers and axonal projections to the superior colliculus.

TFAP2D TFAP2A TFAP2B

1.92e-07675327259519
Pubmed

Polo-Like Kinase 3 Appears Dispensable for Normal Retinal Development Despite Robust Embryonic Expression.

TFAP2D MKI67 TFAP2A TFAP2B

8.81e-073475426949938
Pubmed

Basic molecular fingerprinting of immature cerebellar cortical inhibitory interneurons and their precursors.

VAV3 TFAP2A TFAP2B

1.57e-061175319141316
Pubmed

Activating enhancer binding protein 2 epsilon (AP-2ε)-deficient mice exhibit increased matrix metalloproteinase 13 expression and progressive osteoarthritis development.

TFAP2E TFAP2A TFAP2B

2.09e-061275325964075
Pubmed

The transcription factors AP-2β and AP-2α are required for survival of sympathetic progenitors and differentiated sympathetic neurons.

MKI67 TFAP2A TFAP2B

2.71e-061375321539825
Pubmed

Conditional Deletion of AP-2α and AP-2β in the Developing Murine Retina Leads to Altered Amacrine Cell Mosaics and Disrupted Visual Function.

TFAP2A TFAP2B

4.59e-06275229715367
Pubmed

A human specific Alu DNA cassette is found flanking the genes of transcription factor AP2.

TFAP2D TFAP2B

4.59e-06275230975199
Pubmed

Hepatitis B virus X protein promotes human hepatoma cell growth via upregulation of transcription factor AP2α and sphingosine kinase 1.

SPHK1 TFAP2A

4.59e-06275226073327
Pubmed

AP-2α/AP-2β Transcription Factors Are Key Regulators of Epidermal Homeostasis.

TFAP2A TFAP2B

4.59e-06275238237728
Pubmed

Cloning and characterization of a novel mouse AP-2 transcription factor, AP-2delta, with unique DNA binding and transactivation properties.

TFAP2D TFAP2A

4.59e-06275211522791
Pubmed

Molecular Mechanisms of ZC3H12C/Reg-3 Biological Activity and Its Involvement in Psoriasis Pathology.

ZC3H12A ZC3H12C

4.59e-06275234298932
Pubmed

Positive influence of AP-2alpha transcription factor on cadherin gene expression and differentiation of the ocular surface.

TFAP2A TFAP2B

4.59e-06275212694203
Pubmed

Transcription mapping in a medulloblastoma breakpoint interval and Smith-Magenis syndrome candidate region: identification of 53 transcriptional units and new candidate genes.

TOM1L2 RAI1

4.59e-06275210036180
Pubmed

Cloning and characterization of a second AP-2 transcription factor: AP-2 beta.

TFAP2A TFAP2B

4.59e-0627527555706
Pubmed

Comparative analysis of AP-2 alpha and AP-2 beta gene expression during murine embryogenesis.

TFAP2A TFAP2B

4.59e-0627528989526
Pubmed

Functional Divergence of Mammalian TFAP2a and TFAP2b Transcription Factors for Bidirectional Sleep Control.

TFAP2A TFAP2B

4.59e-06275232769099
Pubmed

AP2 transcription factor induces apoptosis in retinoblastoma cells.

TFAP2A TFAP2B

4.59e-06275220607706
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RPL23 EEFSEC FLII MAGED2 RTCB NUMA1 MKI67 KRR1 TRIP12 NCBP3

5.33e-06759751035915203
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RPL23 RTCB TFAP2E POLH NUMA1 MKI67 KRR1 TRIP12 TFAP2A RAI1 NCBP3

6.17e-06954751136373674
Pubmed

Jmjd3 Plays Pivotal Roles in the Proper Development of Early-Born Retinal Lineages: Amacrine, Horizontal, and Retinal Ganglion Cells.

MKI67 TFAP2A TFAP2B

6.41e-061775332986815
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

EEFSEC FLII MAGED2 RTCB NUMA1 MKI67 AURKAIP1 KRR1 SUCLG2 TRIP12 PRDX6 CPNE7 NCBP3

6.82e-061371751336244648
Pubmed

Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.

FLII NUMA1 MKI67 RNF213 KRR1 TRIP12 NCBP3

7.72e-0633275725693804
Pubmed

KCTD1/KCTD15 complexes control ectodermal and neural crest cell functions, and their impairment causes aplasia cutis.

MKI67 TFAP2A TFAP2B

1.07e-052075338113115
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

FLII ZNF408 NUMA1 TBC1D2B TRIP12 TAPBP RAI1 NCBP3

1.20e-0549775836774506
Pubmed

Sip1 regulates the generation of the inner nuclear layer retinal cell lineages in mammals.

MKI67 TFAP2A TFAP2B

1.25e-052175327385012
Pubmed

Transcriptional activation by Myc is under negative control by the transcription factor AP-2.

TFAP2A TFAP2B

1.37e-0537527729426
Pubmed

Transcription factor AP-2 regulates human insulin-like growth factor binding protein-5 gene expression.

TFAP2A TFAP2B

1.37e-0537527559606
Pubmed

Comprehensive analysis of the expression and prognosis for TFAP2 in human lung carcinoma.

TFAP2A TFAP2B

1.37e-05375232462520
Pubmed

A novel alternative spliced variant of the transcription factor AP2alpha is expressed in the murine ocular lens.

TFAP2A TFAP2B

1.37e-0537529758708
Pubmed

Developmental regulation and overexpression of the transcription factor AP-2, a potential regulator of the timing of Schwann cell generation.

TFAP2A TFAP2B

1.37e-05375211553286
Pubmed

Chromosomal mapping of the human and mouse homologues of two new members of the AP-2 family of transcription factors.

TFAP2A TFAP2B

1.37e-0537528661133
Pubmed

Charting the landscape of tandem BRCT domain-mediated protein interactions.

FLII NUMA1 TBC1D2B MKI67 KRR1 SUCLG2 PRDX6 TULP2 LRRC41

1.40e-0567075922990118
Pubmed

CARM1 is required for proper control of proliferation and differentiation of pulmonary epithelial cells.

SPHK1 MKI67 ACE

1.89e-052475320530543
Pubmed

Illuminating the terminal nerve: Uncovering the link between GnRH-1 neuron and olfactory development.

TFAP2E MKI67 TFAP2A

1.89e-052475338488687
Pubmed

Genes in a refined Smith-Magenis syndrome critical deletion interval on chromosome 17p11.2 and the syntenic region of the mouse.

TOM1L2 FLII RAI1

1.89e-052475311997338
Pubmed

Overlapping expression patterns and redundant roles for AP-2 transcription factors in the developing mammalian retina.

MKI67 TFAP2A TFAP2B

2.14e-052575322411557
Pubmed

AP-2δ is a crucial transcriptional regulator of the posterior midbrain.

TFAP2D TFAP2E TFAP2B

2.14e-052575321858141
Pubmed

Transcription factor AP-2gamma regulates murine adenosine deaminase gene expression during placental development.

TFAP2A TFAP2B

2.75e-0547529765260
Pubmed

Regulation of AP-2 and apoptosis in developing eye in a vitamin A-deficiency model.

TFAP2A TFAP2B

2.75e-05475212749383
Pubmed

A heart-hand syndrome gene: Tfap2b plays a critical role in the development and remodeling of mouse ductus arteriosus and limb patterning.

TFAP2A TFAP2B

2.75e-05475221829553
Pubmed

A novel CCCH-zinc finger protein family regulates proinflammatory activation of macrophages.

ZC3H12A ZC3H12C

2.75e-05475218178554
Pubmed

Distinct and separable activities of the endocytic clathrin-coat components Fcho1/2 and AP-2 in developmental patterning.

TFAP2A FCHO1

2.75e-05475222484487
Pubmed

The interaction of KCTD1 with transcription factor AP-2alpha inhibits its transactivation.

TFAP2A TFAP2B

2.75e-05475219115315
Pubmed

The AP-2 adaptor beta2 appendage scaffolds alternate cargo endocytosis.

TFAP2A TFAP2B

2.75e-05475218843039
Pubmed

p16, cyclin D1, Ki-67, and AMACR as markers for dysplasia in Barrett esophagus.

AMACR MKI67

2.75e-05475218665038
Pubmed

Pax6 is required for normal cell-cycle exit and the differentiation kinetics of retinal progenitor cells.

MKI67 TFAP2A TFAP2B

3.75e-053075324073291
Pubmed

Necessity and Sufficiency of Ldb1 in the Generation, Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

MKI67 TFAP2A TFAP2B

3.75e-053075330127719
Pubmed

Transcription and chromatin regulation by TAF4b during cellular quiescence of developing prospermatogonia.

MKI67 TAF4B

4.57e-05575237900284
Pubmed

Transcription factors AP-2α and AP-2β regulate distinct segments of the distal nephron in the mammalian kidney.

TFAP2A TFAP2B

4.57e-05575235468900
Pubmed

The human reduced folate carrier gene is regulated by the AP2 and sp1 transcription factor families and a functional 61-base pair polymorphism.

TFAP2A TFAP2B

4.57e-05575212228234
Pubmed

Transcription factor AP-2 interacts with the SUMO-conjugating enzyme UBC9 and is sumolated in vivo.

TFAP2A TFAP2B

4.57e-05575212072434
Pubmed

CHD3 and CHD4 form distinct NuRD complexes with different yet overlapping functionality.

RPL23 RTCB BEND7 NUMA1 MKI67 KRR1 RAI1 NCBP3

4.85e-0560575828977666
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

POLH NUMA1 MKI67 TRIP12 TFAP2A RAI1 LRRC41 NCBP3

5.02e-0560875836089195
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

TOM1L2 ENPP6 PMVK EML5 CEP250 BEND7 MLLT3 ACE EPCAM PRDX6

6.43e-051016751019056867
Pubmed

Cardiac malformations, adrenal agenesis, neural crest defects and exencephaly in mice lacking Cited2, a new Tfap2 co-activator.

TFAP2A TFAP2B

6.84e-05675211694877
Pubmed

Physical and functional interactions among AP-2 transcription factors, p300/CREB-binding protein, and CITED2.

TFAP2A TFAP2B

6.84e-05675212586840
Pubmed

AP-2alpha transcription factor is required for early morphogenesis of the lens vesicle.

TFAP2A TFAP2B

6.84e-0567529918694
Pubmed

Ectopic expression of luteinizing hormone-releasing hormone and peripherin in the respiratory epithelium of mice lacking transcription factor AP-2alpha.

MKI67 TFAP2A

6.84e-05675210842061
Pubmed

Transcription factor gene AP-2 gamma essential for early murine development.

TFAP2D TFAP2B

6.84e-05675211940672
Pubmed

TROP2 expressed in the trunk of the ureteric duct regulates branching morphogenesis during kidney development.

MKI67 EPCAM

6.84e-05675222194864
Pubmed

Stromal DLK1 promotes proliferation and inhibits differentiation of the intestinal epithelium during development.

MKI67 EPCAM

6.84e-05675233470182
Pubmed

Anomalous incisor morphology indicates tissue-specific roles for Tfap2a and Tfap2b in tooth development.

TFAP2A TFAP2B

6.84e-05675233460639
Pubmed

Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.

TFAP2A TFAP2B

6.84e-05675215569994
Pubmed

Nuclear High Mobility Group A2 (HMGA2) Interactome Revealed by Biotin Proximity Labeling.

NUMA1 MKI67 TRIP12

7.10e-053775336835656
Pubmed

Spatiotemporal single-cell regulatory atlas reveals neural crest lineage diversification and cellular function during tooth morphogenesis.

ENPP6 MKI67 TFAP2B

7.10e-053775335974052
Pubmed

Prediction of the coding sequences of unidentified human genes. XIX. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SBF2 TMEM108 ZC3H12C DNAH6

7.22e-0510275411214970
Pubmed

NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency.

NUMA1 MKI67 TRIP12 RAI1

7.50e-0510375432744500
Pubmed

Requirement of the Mowat-Wilson Syndrome Gene Zeb2 in the Differentiation and Maintenance of Non-photoreceptor Cell Types During Retinal Development.

MKI67 TFAP2A TFAP2B

8.32e-053975329922981
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

RPL23 MAGED2 MYH7B SYTL2 RNF213

8.96e-0520875533230847
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PLCD3 SBF2 SYTL2 RNF213 TOGARAM1 FCHO1 PRDX6

9.53e-0549375715368895
Pubmed

Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.

FLII RTCB CEP250 MKI67 KRR1 TRIP12

9.54e-0534075629478914
Pubmed

Embryogenic stem cell-derived intestinal crypt fission directs de novo crypt genesis.

MKI67 EPCAM

9.57e-05775236516755
Pubmed

TFAP2 paralogs regulate midfacial development in part through a conserved ALX genetic pathway.

TFAP2A TFAP2B

9.57e-05775238063857
Pubmed

MEGF10 is a mammalian ortholog of CED-1 that interacts with clathrin assembly protein complex 2 medium chain and induces large vacuole formation.

TFAP2A TFAP2B

9.57e-05775217643423
Pubmed

P63 targeted deletion under the FOXN1 promoter disrupts pre-and post-natal thymus development, function and maintenance as well as induces severe hair loss.

MKI67 EPCAM

9.57e-05775235077450
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

NUMA1 MKI67 KRR1 TRIP12 TFAP2A RAI1

1.10e-0434975625665578
Pubmed

Integrin receptors are required for cell survival and proliferation during development of the peripheral glial lineage.

TFAP2A TFAP2B

1.27e-04875211319856
Pubmed

Serotonin transporter protects the placental cells against apoptosis in caspase 3-independent pathway.

MKI67 EPCAM

1.27e-04875228109119
Pubmed

Influence of mesodermal Fgf8 on the differentiation of neural crest-derived postganglionic neurons.

MKI67 TFAP2A

1.27e-04875222040872
Pubmed

Human CREB-binding protein/p300-interacting transactivator with ED-rich tail (CITED) 4, a new member of the CITED family, functions as a co-activator for transcription factor AP-2.

TFAP2A TFAP2B

1.27e-04875211744733
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PLCD3 FLII SH3TC1 KIAA0513 SPHK1 ZNF408 TSNARE1 SBF2 HMGXB3 RAI1

1.28e-041105751035748872
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ENPP6 EML5 SH3TC1 FOXL2NB RNF213 TAF4B KAT6B NCKAP5L RAI1 LRRC41

1.39e-041116751031753913
Pubmed

Potential contribution of neural crest cells to dental enamel formation.

MKI67 TFAP2A

1.64e-04975222020075
Pubmed

Transcriptional programs of Pitx2 and Tfap2a/Tfap2b controlling lineage specification of mandibular epithelium during tooth initiation.

TFAP2A TFAP2B

1.64e-04975239052671
Pubmed

Phenotypic consequences of copy number variation: insights from Smith-Magenis and Potocki-Lupski syndrome mouse models.

TOM1L2 RAI1

1.64e-04975221124890
Pubmed

Cloning of mouse Cited4, a member of the CITED family p300/CBP-binding transcriptional coactivators: induced expression in mammary epithelial cells.

TFAP2A TFAP2B

1.64e-04975212504852
Pubmed

Vav3 mediates receptor protein tyrosine kinase signaling, regulates GTPase activity, modulates cell morphology, and induces cell transformation.

INSR VAV3

1.64e-04975211094073
Pubmed

TFAP2 paralogs regulate melanocyte differentiation in parallel with MITF.

TFAP2A TFAP2B

1.64e-04975228249010
Pubmed

Regulation of the noradrenaline neurotransmitter phenotype by the transcription factor AP-2beta.

TFAP2A TFAP2B

1.64e-04975218424435
Pubmed

Transient Fcho1/2⋅Eps15/R⋅AP-2 Nanoclusters Prime the AP-2 Clathrin Adaptor for Cargo Binding.

TFAP2A FCHO1

2.04e-041075227237791
Pubmed

The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.

RPS6KB1 INSR

2.04e-041075215249583
Pubmed

Loss of HAI-2 in mice with decreased prostasin activity leads to an early-onset intestinal failure resembling congenital tufting enteropathy.

MKI67 EPCAM

2.04e-041075229617460
Pubmed

FoxL1+ mesenchymal cells are a critical source of Wnt5a for midgut elongation during mouse embryonic intestinal development.

MKI67 EPCAM

2.04e-041075233993983
CoexpressionOUYANG_PROSTATE_CANCER_MARKERS

AMACR INSR MKI67 VAV3

3.57e-0721754M9874
CoexpressionOUYANG_PROSTATE_CANCER_MARKERS

AMACR INSR MKI67 VAV3

3.03e-0635754MM757
CoexpressionGSE17721_CTRL_VS_LPS_0.5H_BMDC_DN

ZC3H12A RPS6KB1 SYTL2 MLLT3 ZC3H12C TFAP2B

2.38e-05200756M3680
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAGED2 BEND7 EPCAM TFAP2A SDK1 MAGEF1

1.02e-06197756d6c9da7a3a6d2bcb13e2fc6605c8a59e7fb121c5
ToppCellsaliva-Severe-critical_progression_d28-40-Epithelial-Epithelial,_Airway-secretory_cell-Epi-Secretory|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

MAGED2 BEND7 EPCAM TFAP2A SDK1 MAGEF1

1.02e-0619775680b05c8ad9c1edc5dea3236079372475431343fe
ToppCellfacs-Liver-Liver_non-hepato/SCs_st-18m-Lymphocytic-NK_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGIF2 SYTL2 TAF4B FCHO1 CPNE7

5.51e-06150755973252f4de9a1194aea9f3cb0e1f113643f16c91
ToppCelldroplet-Marrow-nan-21m-Hematologic-erythroid_progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOM1L2 PLCD3 MAGED2 SBF2 ZC3H12C

8.01e-06162755d0ffebf5adee8a3ac9b81a4b793184f54010489a
ToppCellControl-Endothelial-Endothelial-Activated_Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

RNF213 VAV3 ZC3H12C ACE LRRC36

1.44e-05183755e81c142770f44fd902b0631bc360c5b5339d4c75
ToppCellpdx-Tumor_cells-T5|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

FMN1 MLLT3 VAV3 TAF4B SDK1

1.60e-051877557e376831a11ee72ed87abcdac631ca46ae29c250
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FMN1 SYTL2 MLLT3 TFAP2A SDK1

1.73e-051907554836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 EPCAM TFAP2A SDK1 TFAP2B

1.87e-051937550208fcd8ea4662f40fc2c072ac220d97823eec12
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SBF2 VAV3 ZC3H12C ACE LRRC36

1.87e-05193755aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SBF2 VAV3 ZC3H12C ACE LRRC36

1.87e-05193755c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SBF2 VAV3 ZC3H12C ACE LRRC36

1.87e-05193755e1d546165dcc2392f540162206852c4717d7306f
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Control / Condition, Lineage and Cell class

ZC3H12A FMN1 SPHK1 ZC3H12C BCL3

1.91e-05194755a1dd264822de83a0ffaf89ca4707c6a76809359e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 KIAA0513 AMACR SYTL2 LRRC36

2.21e-0520075525f4c051c2e869481f33c22ad54de97efac444ad
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 KIAA0513 AMACR SYTL2 LRRC36

2.21e-05200755da45a85a4667965b24ba824af871157af5b4cd19
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal-Intermediate|GW26 / Sample Type, Dataset, Time_group, and Cell type.

SH3TC1 MYH7B BCL3 KRR1

3.47e-0510975448f675d36fece070410eb9cfe64805f4629e290f
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)-|Striatum / BrainAtlas - Mouse McCarroll V32

TNFAIP8L3 FMN1 HAPLN4 CPNE7

3.60e-051107545496c92932195386025254b9129d69b12c8e3340
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)--|Striatum / BrainAtlas - Mouse McCarroll V32

TNFAIP8L3 FMN1 HAPLN4 CPNE7

3.60e-0511075441306a2d4a5a39569437eb123e47f98ef8afab24
ToppCellStriatum-Neuronal-Inhibitory-iN2(Gad1Gad2)-Inhibitory_Neuron.Gad1Gad2.Pnoc_(Fast-spiking_interneuron,_Pvalb+/Pnoc+)|Striatum / BrainAtlas - Mouse McCarroll V32

TNFAIP8L3 FMN1 HAPLN4 CPNE7

3.60e-051107541fe08060248b25329f73b80d74435c108bee1359
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW26-Mesenchymal-Mesoderm|GW26 / Sample Type, Dataset, Time_group, and Cell type.

ENPP6 EEFSEC DNAH6

3.89e-05397533479d255b87fa8042c51d80a3eb81a774850132e
ToppCellPosterior_cortex-Endothelial-ENDOTHELIAL_TIP-Dcn_1|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

SPHK1 TFAP2A TFAP2B LRRC36

5.56e-0512375428be15b759c152662b29c323b1cc3f02f7830dbe
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Pvalb|Cerebellum / BrainAtlas - Mouse McCarroll V32

EML5 VAV3 TFAP2A TFAP2B

1.17e-041497546e9ca280a599d96f8956ef26f2a46b9484de5488
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|343B / Donor, Lineage, Cell class and subclass (all cells)

AMACR SBF2 TULP2 NCBP3

1.23e-0415175478475027bba9e3026e42493fec8ea630972353bb
ToppCellfacs-Skin-Anagen-3m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZC3H12A SH3TC1 BEND7 TMEM108

1.58e-041617548d2987271da52fd8353557ac6faa4f7a4be0ed2a
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Medullary_Thick_Ascending_Limb_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TFAP2E TSNARE1 DNAH6 TFAP2B

1.65e-04163754cab65dabeea58141c649e4fec5e0123beb3de1b3
ToppCell343B-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

AMACR SBF2 TULP2 NCBP3

1.65e-041637540ab043b68e8739adcedda01165a3758cd0d22728
ToppCellPND28-Immune-Immune_Myeloid-DC-cDC1|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL23 EEFSEC MKI67 SDK1

1.69e-041647545638d95c7cc5e59c4a7bda30268a904a01861a5f
ToppCellCerebellum-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)|Cerebellum / BrainAtlas - Mouse McCarroll V32

HAPLN4 VAV3 TFAP2A TFAP2B

1.81e-041677549efb9511a211d0824bb97f82c1a5860c43d2138f
ToppCellCerebellum-Neuronal-Inhibitory|Cerebellum / BrainAtlas - Mouse McCarroll V32

HAPLN4 VAV3 TFAP2A TFAP2B

1.81e-04167754904c613aac3f9919a432b110bb1dcc832b5aec0a
ToppCelldroplet-Liver-HEPATOCYTES-1m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGIF2 CEP250 TAF4B FCHO1

1.90e-04169754d721dbb317a88113b4f76688111908d00f23e899
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPCAM TFAP2A FCHO1 CPNE7

1.94e-04170754bcbe5c44ef708c5f01dc7dd9aec7b436e1a62d56
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-10|TCGA-Brain / Sample_Type by Project: Shred V9

GAS2L2 EFCAB12 TTC34 DNAH6

1.98e-0417175474be8d3bf6b99e2d734635a8b1a7c41e8c596959
ToppCelldroplet-Liver-nan-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLCD3 FMN1 SPHK1 TULP2

2.03e-04172754f814b6134ad608015765399d54cc1e5e1873ed34
ToppCelldroplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EEFSEC TGIF2 TAF4B EPCAM

2.03e-04172754b043d4f81dced7fb3326043f68474123be47cc5d
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_28|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EML5 KIAA0513 INSR ACE

2.07e-0417375466488d01e03264fb193285470901c9c4182fbae8
ToppCelldroplet-Liver-Npc-21m-Lymphocytic|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPCAM TFAP2B FCHO1 CPNE7

2.17e-04175754046e841811b22c39f80a9752f3223c1906de6f20
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_macrophage_(16)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZC3H12A FMN1 SPHK1 ZC3H12C

2.21e-0417675498176bf3c961d5262593e2d5d002836adb010e13
ToppCell10x5'v1-week_17-19-Hematopoietic-HSC/MPP_and_pro-MEP|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MAGED2 TMEM108 TAF4B CPNE7

2.31e-04178754b8c301d65c0f37941e8e9414d55e90edb6ecc195
ToppCellAdult-Epithelial-club_cell-D122|Adult / Lineage, Cell type, age group and donor

INSR MLLT3 TMEM108 TFAP2B

2.31e-0417875435a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TNFAIP8L3 SH3TC1 SPHK1 VAV3

2.36e-04179754ab3d08b51cd7a37582305615ee221c7a2af83b40
ToppCellPCW_10-12-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

TNFAIP8L3 SH3TC1 SPHK1 VAV3

2.36e-0417975435fe9961e228ce255e3317fc244efa35b5adbf8b
ToppCelldroplet-Tongue-Unstain-18m-Epithelial-suprabasal_interpapillary|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PMVK KIAA0513 FCHO1 PRDX6

2.41e-0418075418bf8561ad3aa9787d2a8ef942a96f641734c608
ToppCellfacs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EML5 HAPLN4 TFAP2A TFAP2B

2.41e-041807543d54cc767e25d91ed2203d8a03e5bf5e15f21699
ToppCell390C-Lymphocytic-CD4_T-cell-Treg_cell_2|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

ZNF408 TRIP12 EPCAM MAGEF1

2.52e-0418275421744c9c792e57d5d41b25986f419b2358c7057b
ToppCellE18.5-samps-Endothelial-Mature_fetal_endothelial-endothelial_cells_A|E18.5-samps / Age Group, Lineage, Cell class and subclass

MKI67 RNF213 VAV3 ACE

2.52e-04182754ea4f6c8f600ffe9f8e0609637b3371a5ac48ca03
ToppCellStriatum-Macroglia-POLYDENDROCYTE-P5-P5_2-Sox4-POLYDENDROCYTE_(Rostral-�migratory_stream-�(RMS)_(Notum))|Striatum / BrainAtlas - Mouse McCarroll V32

TGIF2 ZC3H12A TFAP2E

2.54e-047375350a8164d967f2706344adcdc1562dc08c9f16c8f
ToppCelldroplet-Kidney-nan-3m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPHK1 SYTL2 EPCAM TFAP2B

2.57e-041837546b5fa169477821355d1ab7aa11935cdfde1c339c
ToppCell343B-Lymphocytic-CD4_T-cell-Treg_cell_4|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

SH3TC1 ZNF408 VAV3 EPCAM

2.57e-041837543cbe0175d05fd39bc430de1ef471ff2c5b56460e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 MLLT3 EPCAM TFAP2A

2.62e-041847549690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCell3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TNFAIP8L3 SH3TC1 SPHK1 VAV3

2.68e-04185754fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic-endo_lymphatic_(7)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TNFAIP8L3 SH3TC1 SPHK1 VAV3

2.68e-041857543be9e05b929ac4d956b1d53284072f668a6c1959
ToppCellTCGA-Kidney-Primary_Tumor-Renal_Cell_Carcinoma-Kidney_Papillary_Renal_Cell_Carcinoma|TCGA-Kidney / Sample_Type by Project: Shred V9

PLCD3 FLII AMACR CPNE7

2.68e-0418575446f4f6f20b1e152922f6f2ba1244c56e48a49b79
ToppCellPCW_13-14-Endothelial-Endothelial_mature-lymphatic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TNFAIP8L3 SH3TC1 SPHK1 VAV3

2.68e-04185754c3dd64a726cb8a1fe048683c266b7532a714a52e
ToppCelldroplet-Lung-LUNG-1m-Epithelial-Club_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L3 BEND7 HMGXB3 SDK1

2.73e-04186754e52cf44989c57c433bf82e9fa13b4643e88f3577
ToppCelldroplet-Lung-LUNG-1m-Epithelial-club_cell_of_bronchiole|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L3 BEND7 HMGXB3 SDK1

2.73e-041867544c0b59d845b79323e7a3287e7c4d249f5f322556
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEFSEC TFAP2E SUCLG2 EPCAM

2.73e-04186754246503fd4e6ae24041c606b069eb5fb313e60f73
ToppCellfacs-Heart-LA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EEFSEC TFAP2E SUCLG2 EPCAM

2.73e-04186754ef93ac469eb4f63db036f14b442c1503b8c6de38
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 MLLT3 EPCAM TFAP2A

2.73e-04186754b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCellControl-Endothelial-Endothelial-Alv_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

VAV3 ZC3H12C ACE LRRC36

2.79e-04187754ea9d34bcd3bd1f36745846309ede349773de501a
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLII SH3TC1 TBC1D2B ACE

2.79e-041877543699d5e71d779da922920aa3160895db187bf81b
ToppCellE18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLII SH3TC1 TBC1D2B ACE

2.79e-04187754033ba52c0c2f9978784947098fa697368ae44834
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 MLLT3 TFAP2A SDK1

2.90e-041897548ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZC3H12A FMN1 SPHK1 ZC3H12C

2.90e-04189754440c422369de1c49112d18cf8c506a2a3a81f6ba
ToppCelldroplet-Tongue-nan-24m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL23 ZC3H12A MKI67 BCL3

2.90e-04189754258ef4a52f90236dbed92f325ca033c8fa6156a5
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOM1L2 SYTL2 EPCAM TFAP2B

2.96e-04190754c247562df3e1aa3173c9f01a74d5831f0764a1b2
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOM1L2 SYTL2 EPCAM TFAP2B

2.96e-041907545cea8298c8336c136ba009630c9e48d4bc832cb2
ToppCellPCW_10-12-Hematologic_Myeloid-Hem_Myeloid_macrophage-im_immature_macrophage2_(0)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ZC3H12A FMN1 SPHK1 ZC3H12C

2.96e-04190754e0b363f772817cfc6ab425430805c1cddcba23f0
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VAV3 TAF4B TFAP2B PRDX6

2.96e-04190754498bbe063bc75d323cb186a82cce122b511d2cff
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPHK1 BEND7 EPCAM PRDX6

3.02e-04191754ce76b156b153a2c7c9f2fb8e563b69c81073fbe5
ToppCellPND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SPHK1 BEND7 EPCAM PRDX6

3.02e-04191754c006f5a6e3a32b79ac99a78304bdd5116fc0d5e0
ToppCell15-Trachea-Epithelial-Submucosal_gland_basal|Trachea / Age, Tissue, Lineage and Cell class

SPHK1 HAPLN4 TMEM108 TFAP2A

3.02e-04191754409e12d2bb26b6d2ed025304ca6ace07df16638a
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-basal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGIF2 SPHK1 BCL3 NCKAP5L

3.02e-041917548691eba35793e4e90f93d50c2145847ee51289f7
ToppCellP03-Epithelial-alveolar_epithelial_cell-type_I_pneumocyte|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

SPHK1 BEND7 EPCAM PRDX6

3.08e-04192754be5e246b2350398b985767b2fbede17a8dd8cc44
ToppCellRV-08._Macrophage|World / Chamber and Cluster_Paper

FMN1 MKI67 RNF213 VAV3

3.08e-04192754a1b5dc5beb97a23729b97b54fb4574d10d8fbfb3
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____thick_ascending_tube_S_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL2 VAV3 EPCAM TFAP2B

3.08e-04192754e19e3e8edcc08e4a67873bfb6e46489ca6c8756a
ToppCelldroplet-Kidney-nan-18m-Epithelial-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SYTL2 VAV3 EPCAM TFAP2B

3.08e-0419275461c2caf6c838132ed5faa8791c288f2149eba2c8
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2-AT1/AT2_mature|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMVK BEND7 EPCAM PRDX6

3.14e-041937541fdfe08b0c82248545c29b504ac259b093fde29b
ToppCellBAL-Control-Myeloid-MoAM-MoAM3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZC3H12A SPHK1 ZC3H12C BCL3

3.14e-04193754837c61408462c519912ecf3b83fdc72cd85fe88f
ToppCellControl-Myeloid-MoAM3|Control / Disease group,lineage and cell class （2021.01.30）

ZC3H12A SPHK1 ZC3H12C BCL3

3.14e-0419375497d2f12be43fc26efa84ac4c6119132928a123de
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-kidney_collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPCAM TFAP2A SDK1 TFAP2B

3.14e-0419375404d47ba7cc1f19f1ffb18d9e68469e75063697cf
ToppCellBAL-Control-Myeloid-MoAM-MoAM3|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ZC3H12A SPHK1 ZC3H12C BCL3

3.14e-04193754d81840e1322507552b7726bf7828309375162324
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1/AT2|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMVK BEND7 EPCAM PRDX6

3.14e-041937545f90e3e526032d82d9dc7e0813fe79ca28dc0719
ToppCellPCW_07-8.5-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SH3TC1 BEND7 VAV3 ACE

3.14e-0419375472d20ee257149b238016b44d183ce3fc24b8f621
ToppCellBAL-Control-Myeloid-MoAM-MoAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ZC3H12A SPHK1 ZC3H12C BCL3

3.14e-04193754e4ca3a3c2704cdc52e6ac3f25f14debf74226c29
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Degenerative_Distal_Convoluted_Tubule_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FMN1 VAV3 TAF4B TFAP2A

3.14e-04193754dd9874898587fe9fd9cf2aebc2e0579dcf06944e
ToppCellBAL-Control-Myeloid-MoAM-MoAM3-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ZC3H12A SPHK1 ZC3H12C BCL3

3.14e-04193754e54f8b6381b5a96758cff41ab12d6f60cfca29a9
ToppCellPND01|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RPL23 PMVK SPHK1 PRDX6

3.14e-04193754c291345c11cfcbceacbdc001a5851f67478a2779
ToppCellControl-Myeloid-MoAM5,_CCL3L1|Myeloid / Condition, Lineage and Cell class

FMN1 SPHK1 ZC3H12C BCL3

3.21e-0419475496400477d130b2403ed81c229e4e4182cc2cdc14
ToppCellBAL-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FMN1 SPHK1 ZC3H12C BCL3

3.21e-04194754a4523adbbd25c314809eed3414d66a5b323446e5
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INSR MLLT3 EPCAM TFAP2B

3.21e-041947540cd4363627acd419e00d6d32f6dce10430aa6487
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FMN1 VAV3 TAF4B TFAP2A

3.21e-04194754f08a7618a9ccf12e4a7620235ae662a8abc521af
ToppCellnucseq-Epithelial-Epithelial_Alveolar-Secretory/RAS-RAS|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

INSR MLLT3 EPCAM TFAP2B

3.21e-04194754a58841b34efe673671a9a059238e044a7254b279
ToppCellBAL-Control-Myeloid-MoAM|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FMN1 SPHK1 ZC3H12C BCL3

3.21e-04194754125bf2909cf89133693bc7b865ca08955cf67a2e
ToppCellPND01-Epithelial|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMVK BEND7 EPCAM PRDX6

3.21e-04194754d21db5e942966ed44bc78ff50130a201fc627074
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 RNF213 SDK1 TFAP2B

3.27e-04195754938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCellfacs-Mammary_Gland|facs / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TGIF2 SPHK1 BCL3 EPCAM

3.27e-0419575421cfcb751e548591fc8724a8329c294da6012e0f
ToppCellPND01-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMVK BEND7 EPCAM PRDX6

3.27e-0419575443164511f32e4591cb5399182fbac0b911716233
ToppCellPND01-Epithelial-Epithelial_Alveolar|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

PMVK BEND7 EPCAM PRDX6

3.27e-041957549337111d75a487abc02969337718c30b1fe81379
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYTL2 RNF213 SDK1 TFAP2B

3.27e-04195754d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_4|COVID-19_Severe / Disease condition and Cell class

ZC3H12A SPHK1 RNF213 BCL3

3.27e-04195754787ea9f38ad8e2a836222ca97f4d927f7e79517d
ToppCellEpithelial-A_(AT1)|World / shred on cell class and cell subclass (v4)

SPHK1 BEND7 EPCAM PRDX6

3.33e-04196754484bbc6b1f58bc260964babb949d14f5df101393
Drug2-amino-4-chloro-6-hydroxy-s-triazine

TFAP2D TFAP2E TFAP2A TFAP2B

1.92e-0716754CID000430167
DrugHMP-P

TFAP2D TFAP2E TFAP2A TFAP2B

1.92e-0716754CID000000216
DrugNSC 308880

TFAP2D TFAP2E TFAP2A TFAP2B

2.50e-0717754CID000073599
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

TGIF2 CEP250 SYTL2 NUMA1 BCL3 TAF4B LRRC41

3.00e-061897575203_DN
Drugphenelzine

TFAP2D TFAP2E TFAP2A TFAP2B

4.67e-0634754CID000003675
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A

FLII SPHK1 BCL3 KAT6B TFAP2A LRRC41

2.38e-051747566493_DN
Drugpanaxadiol

TFAP2D TFAP2A TFAP2B

2.70e-0518753CID000073498
DrugPrimaquine diphosphate [63-45-6]; Down 200; 8.8uM; MCF7; HT_HG-U133A

TGIF2 TESK2 MLLT3 HMGXB3 KAT6B TFAP2A

3.67e-051887564845_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; PC3; HT_HG-U133A

ZNF408 CEP250 NUMA1 HMGXB3 BCL3 TAF4B

4.38e-051947561223_DN
DrugDanazol [17230-88-5]; Down 200; 11.8uM; MCF7; HT_HG-U133A

ZC3H12A SPHK1 ZNF408 SYTL2 MLLT3 VAV3

4.50e-051957565315_DN
DrugLY 294002; Down 200; 10uM; PC3; HT_HG-U133A

RPL23 TGIF2 SYTL2 TAF4B TFAP2A MAGEF1

4.50e-051957561239_DN
DrugEtodolac [41340-25-4]; Down 200; 14uM; MCF7; HT_HG-U133A

ZC3H12A CEP250 NUMA1 MLLT3 KAT6B MAGEF1

4.90e-051987567006_DN
DrugSulfapyridine [144-83-2]; Down 200; 16uM; HL60; HT_HG-U133A

PTGES2 TGIF2 ZC3H12A NUMA1 KAT6B LRRC41

4.90e-051987562538_DN
Drughaloperidol; Down 200; 10uM; PC3; HT_HG-U133A

TGIF2 ZC3H12A ZNF408 NUMA1 BCL3 MAGEF1

4.90e-051987561244_DN
DrugGelsemine [509-15-9]; Down 200; 12.4uM; MCF7; HT_HG-U133A

FLII KIAA0513 SPHK1 TESK2 FCHO1 LRRC41

4.90e-051987562817_DN
Druggliclazide

TNFAIP8L3 INSR ACE EPCAM

4.92e-0561754CID000003475
Drugdona

TFAP2D TNFAIP8L3 TFAP2E KRR1 TFAP2A TFAP2B

5.33e-05201756CID000000739
Drugginsenoside Rb2

TFAP2D TFAP2A TFAP2B

5.80e-0523753CID000073598
Diseasesleep disorder (implicated_via_orthology)

TFAP2D TFAP2E INSR TFAP2A TFAP2B

3.95e-1111745DOID:535 (implicated_via_orthology)
DiseaseClinodactyly

TFAP2A TFAP2B

3.71e-054742C4551485
DiseaseSmith-Magenis syndrome

FLII RAI1

3.71e-054742C0795864
DiseaseClinodactyly of fingers

TFAP2A TFAP2B

3.71e-054742C0265610
Diseasealcohol dependence (implicated_via_orthology)

RPS6KB1 INSR

2.21e-049742DOID:0050741 (implicated_via_orthology)
Diseaseparahippocampal gyrus volume measurement

TFAP2D MAGEF1

9.25e-0418742EFO_0010318
Diseaserenal system measurement, blood urea nitrogen measurement

TFAP2D TFAP2B

1.39e-0322742EFO_0004741, EFO_0004742
Diseasemean arterial pressure

C16orf90 TFAP2D INSR RNF213 TRIP12 TFAP2B

1.59e-03499746EFO_0006340
DiseaseLeft Ventricular Hypertrophy

RPS6KB1 ACE

1.79e-0325742C0149721
DiseaseCalcium channel blocker use measurement

SBF2 INSR RNF213 ACE

2.05e-03213744EFO_0009930
Diseaseglucose metabolism disease (implicated_via_orthology)

RPS6KB1 INSR

2.25e-0328742DOID:4194 (implicated_via_orthology)
Diseaseprimary biliary cholangitis (biomarker_via_orthology)

RPS6KB1 ACE

2.25e-0328742DOID:12236 (biomarker_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
GLIRRKSIAPANGNL

ERI2

11

A8K979
SKLGRRAKPEGALQN

EPCAM

76

P16422
GAKLRKVLQAGSSRP

ACE

566

P12821
LGRGKRSLVLDLKQP

AMACR

46

Q9UHK6
FRRKLLKAGGDPNRS

MLLT3

131

P42568
KIGLNLPAGRRKAAN

TFAP2A

271

P05549
NLALLRSQGPGKSKR

EFCAB12

451

Q6NXP0
SLLGGVLRRAKSKNG

TFAP2B

266

Q92481
RLGLNLPAGRRKAAN

TFAP2D

271

Q7Z6R9
LEKIGLNLPAGRRKA

TFAP2E

276

Q6VUC0
ALAPKKRSRKGRAGA

RAI1

1441

Q7Z5J4
NKRRAGLPLGGHKSL

FMN1

456

Q68DA7
AKRAVNNGRLLKDGP

KAT6B

156

Q8WYB5
GGLETKLKGPLARRN

KIAA0513

246

O60268
KRLRGAKAFRLPGLS

FCHO1

281

O14526
KSPRLVRAAALKLGQ

FLII

791

Q13045
ALLSLRSPKARRGKA

MAGED2

241

Q9UNF1
EPALTRKGARALAAK

MAGEF1

51

Q9HAY2
LRDRLAALGKLKTGP

NCKAP5L

661

Q9HCH0
TLPAALRALKGKAAR

SBF2

571

Q86WG5
RKLGPQRGKALQASS

FOXL2NB

16

Q6ZUU3
KGRARGKPSLLAAAR

HMGXB3

501

Q12766
ANKLRARTRDALGPK

MYH7B

1966

A7E2Y1
LSLHGSLGKRPQRSK

LRRC36

341

Q1X8D7
LLRNDLRPANKLAKG

NCBP3

241

Q53F19
KLLKRNAASRLGAGP

RPS6KB1

326

P23443
RQRLIGPKGSTLKAL

KRR1

161

Q13601
GGKKNGRILTLPRSN

INSR

1366

P06213
EKLDLLGNLPGSKRR

MKI67

1926

P46013
SVKGIKGRLNRLPAA

RPL23

41

P62829
SKLERKRKNILGAPG

DNAH6

2141

Q9C0G6
PKDRLLRAVLGSKGG

GAS2L2

811

Q8NHY3
VTRPLLLKFGRNAGK

CPNE7

201

Q9UBL6
NGARSLFKRGPLLTA

CEP250

1221

Q9BV73
GSKPKNFRLRHLRGL

C16orf90

51

A8MZG2
LLLTAPAGAQRGRKK

HAPLN4

21

Q86UW8
ANSLPNGKRKRGLND

BEND7

326

Q8N7W2
IKRAALAPGSKGLLL

EML5

941

Q05BV3
ALALGLAQPASARRK

ENPP6

11

Q6UWR7
AKARLPLEALLGSNK

BLID

41

Q8IZY5
KAAGLPGAALPLRKR

BCL3

21

P20749
KVLASGGLRIQKLRP

SDK1

436

Q7Z5N4
PKKLGNSLLRRGASK

NUMA1

2056

Q14980
KVSARAKKRGLPQLG

RTCB

206

Q9Y3I0
DSLKARGAPRGILKR

SYTL2

261

Q9HCH5
ANLTALAAIGPRKKR

TAF4B

786

Q92750
NSTLKGLRLPGNRLG

LRRC41

701

Q15345
LGRAAKLAPEFAKRN

PRDX6

51

P30041
GRLAQARGAAKKAGL

SH3TC1

541

Q8TE82
ARKGSPRLLGAAALA

PTGES2

51

Q9H7Z7
PIRKIRSLGGKLGAS

POLH

251

Q9Y253
GAPRLVLLFSGKRKS

PMVK

6

Q15126
GLLSLAGKRKRRGNL

TGIF2

11

Q9GZN2
GRAASLPRKGAQLEL

AURKAIP1

46

Q9NWT8
VSRFLQGKPRLSLKG

RNF213

4961

Q63HN8
AAQAGKLLRALALRP

SUCLG2

6

Q96I99
PALKKRARAGRGEAT

EEFSEC

546

P57772
LQRGKGLAAPLSALS

TNFAIP8L3

51

Q5GJ75
LLGDRGLGNPFLRKK

TULP2

66

O00295
LGRHGPSLDNFLRKK

ZC3H12A

281

Q5D1E8
RRKLGDLRKAAHGPS

TSNARE1

196

Q96NA8
IAFKGRRKNLDLAAP

PLCD3

141

Q8N3E9
KGLAKRPGALLLRQG

TAPBP

36

O15533
GKKALQLAREPRLGL

ZNF408

11

Q9H9D4
LNPRGGKGKALQLFR

SPHK1

21

Q9NYA1
QAKARLLPGADRKRS

TCF23

21

Q7RTU1
LGRHGPSLDNFLRKK

ZC3H12C

391

Q9C0D7
TRRVLSAGKGKNKLP

TOGARAM1

646

Q9Y4F4
ARGLLEKAPGVKRLS

TESK2

331

Q96S53
GPKDAIRALKKRLNG

TOM1L2

46

Q6ZVM7
GPSGLQAKLASLRKS

TRIP12

291

Q14669
AARARLGLLQLKKGD

TTC34

341

A8MYJ7
LQKLSGKGPLRGYRS

TBC1D2B

41

Q9UPU7
LGPAKDKPGLRRAAQ

TMEM108

271

Q6UXF1
RGNRAGNSLLSPKVL

VAV3

776

Q9UKW4