Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainPDZ

MPP1 MPP2 SYNPO2 MPP4 FRMPD2 APBA1

4.17e-05141846PF00595
DomainSH3_2

MPP1 MPP2 DOCK3 MYO7B MPP4

4.27e-0586845PF07653
DomainSH3_2

MPP1 MPP2 DOCK3 MYO7B MPP4

4.27e-0586845IPR011511
DomainGuanylate_kinase_CS

MPP1 MPP2 MPP4

4.71e-0516843IPR020590
DomainPDZ

MPP1 MPP2 SYNPO2 MPP4 FRMPD2 APBA1

5.47e-05148846SM00228
Domain-

MPP1 MPP2 SYNPO2 MPP4 FRMPD2 APBA1

5.89e-051508462.30.42.10
DomainPDZ

MPP1 MPP2 SYNPO2 MPP4 FRMPD2 APBA1

6.11e-05151846PS50106
DomainPDZ

MPP1 MPP2 SYNPO2 MPP4 FRMPD2 APBA1

6.34e-05152846IPR001478
Domain-

MPP1 MPP2 LONP1 UTP25 MYO7B DYNC2H1 MPP4 ATAD2B GET3 APAF1 AQR DNAH11

1.22e-0474684123.40.50.300
DomainGUANYLATE_KINASE_2

MPP1 MPP2 MPP4

1.46e-0423843PS50052
DomainGUANYLATE_KINASE_1

MPP1 MPP2 MPP4

1.46e-0423843PS00856
DomainGuanylate_kin

MPP1 MPP2 MPP4

2.12e-0426843PF00625
DomainGK/Ca_channel_bsu

MPP1 MPP2 MPP4

2.12e-0426843IPR008145
DomainGuanylate_kin-like_dom

MPP1 MPP2 MPP4

2.12e-0426843IPR008144
DomainGuKc

MPP1 MPP2 MPP4

2.12e-0426843SM00072
DomainP-type_ATPase_IIC

ATP1A2 ATP1A4

2.96e-046842IPR005775
DomainP-loop_NTPase

MPP1 MPP2 LONP1 UTP25 MYO7B DYNC2H1 MPP4 ATAD2B GET3 APAF1 AQR DNAH11

3.95e-048488412IPR027417
DomainClathrin

WDR19 CLTC

4.14e-047842PF00637
DomainZnf_FYVE_PHD

BPTF KMT2C HGS ASH1L BSN

5.29e-04147845IPR011011
DomainClathrin_H-chain/VPS_repeat

WDR19 CLTC

5.50e-048842IPR000547
DomainDHC_N1

DYNC2H1 DNAH11

5.50e-048842PF08385
DomainDynein_heavy_dom-1

DYNC2H1 DNAH11

5.50e-048842IPR013594
DomainBROMODOMAIN_1

BPTF ATAD2B ASH1L

6.11e-0437843PS00633
DomainBromodomain

BPTF ATAD2B ASH1L

6.61e-0438843PF00439
DomainBROMODOMAIN_2

BPTF ATAD2B ASH1L

8.27e-0441843PS50014
DomainL27_C

MPP2 MPP4

8.79e-0410842IPR014775
DomainL27

MPP2 MPP4

8.79e-0410842PF02828
DomainBromodomain

BPTF ATAD2B ASH1L

8.88e-0442843IPR001487
DomainBROMO

BPTF ATAD2B ASH1L

8.88e-0442843SM00297
Domain-

BPTF ATAD2B ASH1L

8.88e-04428431.20.920.10
DomainPeptidase_M28

NAALAD2 NCLN

1.28e-0312842PF04389
DomainPeptidase_M28

NAALAD2 NCLN

1.28e-0312842IPR007484
DomainL27

MPP2 MPP4

1.51e-0313842SM00569
DomainL27

MPP2 MPP4

1.51e-0313842PS51022
DomainL27_dom

MPP2 MPP4

1.51e-0313842IPR004172
DomainHMG_box

SOX1 KMT2C TOX

1.75e-0353843PF00505
DomainDynein_heavy_chain_D4_dom

DYNC2H1 DNAH11

1.76e-0314842IPR024317
DomainDynein_HC_stalk

DYNC2H1 DNAH11

1.76e-0314842IPR024743
DomainDynein_heavy_dom-2

DYNC2H1 DNAH11

1.76e-0314842IPR013602
DomainDHC_N2

DYNC2H1 DNAH11

1.76e-0314842PF08393
DomainATPase_dyneun-rel_AAA

DYNC2H1 DNAH11

1.76e-0314842IPR011704
DomainMT

DYNC2H1 DNAH11

1.76e-0314842PF12777
DomainAAA_8

DYNC2H1 DNAH11

1.76e-0314842PF12780
DomainAAA_5

DYNC2H1 DNAH11

1.76e-0314842PF07728
DomainHMG

SOX1 KMT2C TOX

1.84e-0354843SM00398
DomainDHC_fam

DYNC2H1 DNAH11

2.02e-0315842IPR026983
DomainDynein_heavy

DYNC2H1 DNAH11

2.02e-0315842PF03028
DomainDynein_heavy_dom

DYNC2H1 DNAH11

2.02e-0315842IPR004273
DomainPost-SET_dom

KMT2C ASH1L

2.30e-0316842IPR003616
DomainPostSET

KMT2C ASH1L

2.30e-0316842SM00508
DomainATPase_P-typ_TM_dom

ATP1A2 ATP1A4

2.30e-0316842IPR023298
Domain-

ATP1A2 ATP1A4

2.30e-03168421.20.1110.10
DomainPOST_SET

KMT2C ASH1L

2.30e-0316842PS50868
DomainATPase_P-typ_cation-transptr_C

ATP1A2 ATP1A4

2.60e-0317842IPR006068
DomainCation_ATPase_C

ATP1A2 ATP1A4

2.60e-0317842PF00689
DomainSH3

MPP1 MPP2 DOCK3 MYO7B MPP4

2.91e-03216845SM00326
DomainSH3

MPP1 MPP2 DOCK3 MYO7B MPP4

2.91e-03216845PS50002
DomainCation_ATPase_N

ATP1A2 ATP1A4

2.92e-0318842PF00690
DomainCation_ATPase_N

ATP1A2 ATP1A4

2.92e-0318842SM00831
DomainHMG_box_dom

SOX1 KMT2C TOX

3.14e-0365843IPR009071
DomainSH3_domain

MPP1 MPP2 DOCK3 MYO7B MPP4

3.15e-03220845IPR001452
DomainATPase_P-typ_cation-transptr_N

ATP1A2 ATP1A4

3.25e-0319842IPR004014
DomainAAA

LONP1 DYNC2H1 ATAD2B DNAH11

4.06e-03144844SM00382
DomainAAA+_ATPase

LONP1 DYNC2H1 ATAD2B DNAH11

4.06e-03144844IPR003593
DomainARM-type_fold

DOCK3 USO1 UBR4 CLTC RANBP6 PPP4R4

4.24e-03339846IPR016024
DomainCupredoxin

PADI2 F5

4.36e-0322842IPR008972
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

LONP1 USO1 DYNC2H1 SUPT6H DNAJA2 UBR4 FN3KRP CLTC NAP1L1 XIAP NCLN BSN PGK1 AQR NOMO1

2.35e-061425871530948266
Pubmed

An ER translocon for multi-pass membrane protein biogenesis.

SEC61G NCLN NOMO1

2.46e-061187332820719
Pubmed

LCP1 preferentially binds clasped αMβ2 integrin and attenuates leukocyte adhesion under flow.

MPP1 UTP25 PABPC3 DNAJA2 UBR4 CLTC PGK1 NOMO1

2.50e-0634487830333137
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

MPP2 DOCK3 LONP1 PLPPR4 DNAJA2 UBR4 CLTC APBA1 PER1 ATP1A2 NCLN BSN PGK1

5.04e-061139871336417873
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

BPTF LONP1 UTP25 SUPT6H ATAD2B UBR4 CLTC NAP1L1 PGK1 AQR

5.55e-06653871022586326
Pubmed

Chromosomal mapping of two members of the human dynein gene family to chromosome regions 7p15 and 11q13 near the deafness loci DFNA 5 and DFNA 11.

DYNC2H1 DNAH11

6.19e-0628729325061
Pubmed

cDNA sequence and genomic structure of the murine p55 (Mpp1) gene.

MPP1 MPP2

6.19e-0628728954807
Pubmed

The Na,K-ATPase alpha4 gene (Atp1a4) encodes a ouabain-resistant alpha subunit and is tightly linked to the alpha2 gene (Atp1a2) on mouse chromosome 1.

ATP1A2 ATP1A4

6.19e-06287210555956
Pubmed

Expanding Our Knowledge of Molecular Pathogenesis in Histiocytoses: Solitary Soft Tissue Histiocytomas in Children With a Novel CLTC::SYK Fusion.

CLTC SYK

6.19e-06287237522373
Pubmed

Flat clathrin coats on endosomes mediate degradative protein sorting by scaffolding Hrs in dynamic microdomains.

HGS CLTC

6.19e-06287216720641
Pubmed

Syk-dependent regulation of Hrs phosphorylation and ubiquitination upon FcεRI engagement: impact on Hrs membrane/cytosol localization.

HGS SYK

6.19e-06287222706924
Pubmed

Hrs recruits clathrin to early endosomes.

HGS CLTC

6.19e-06287211532964
Pubmed

Proteomic analysis of cerebrospinal fluid extracellular vesicles: a comprehensive dataset.

SLC39A12 CLTC ATP1A2 F5

7.70e-065087424769233
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

DOCK3 CACNA1S SYNPO2 USF3 UBR4 CLTC MAU2 BSN

1.27e-0543087835044719
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

WDR19 DOCK3 DNAJA2 UBR4 CLTC ASH1L APBA1 NAP1L1 ATP1A2 PADI2 KDM6A PGK1 LGI1

1.82e-051285871335914814
Pubmed

Protein Z-dependent protease inhibitor deficiency produces a more severe murine phenotype than protein Z deficiency.

SERPINA10 F5

1.85e-05387218344422
Pubmed

The histone chaperone Spt6 coordinates histone H3K27 demethylation and myogenesis.

SUPT6H KDM6A

1.85e-05387223503590
Pubmed

Syk and Hrs Regulate TLR3-Mediated Antiviral Response in Murine Astrocytes.

HGS SYK

1.85e-05387231089414
Pubmed

Defining the membrane proteome of NK cells.

MPP1 LONP1 USO1 UBR4 CLTC NAP1L1 NCLN ITGAX F5 PGK1 AQR NOMO1

3.39e-051168871219946888
Pubmed

Fine mapping of the autosomal recessive polycystic kidney disease locus (PKHD1) and the genes MUT, RDS, CSNK2 beta, and GSTA1 at 6p21.1-p12.

PKHD1 MMUT

3.70e-0548729503014
Pubmed

Preactivation of AMPK by metformin may ameliorate the epithelial cell damage caused by renal ischemia.

ATP1A2 ATP1A4

3.70e-05487221849490
Pubmed

Syk activation of phosphatidylinositol 3-kinase/Akt prevents HtrA2-dependent loss of X-linked inhibitor of apoptosis protein (XIAP) to promote survival of Epstein-Barr virus+ (EBV+) B cell lymphomas.

SYK XIAP

3.70e-05487221908615
Pubmed

HIF-1 regulates cytochrome oxidase subunits to optimize efficiency of respiration in hypoxic cells.

LONP1 COX4I2

3.70e-05487217418790
Pubmed

A tagging-via-substrate technology for detection and proteomics of farnesylated proteins.

DNAJA2 NAP1L1

3.70e-05487215308774
Pubmed

Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice.

SYK ITGAX

3.70e-05487223521885
Pubmed

Proteomic Analysis Reveals a Role for RSK in p120-catenin Phosphorylation and Melanoma Cell-Cell Adhesion.

MPP1 NAP1L1 SFXN2 RANBP6 NCLN

5.28e-0516087531678930
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

MPP2 LONP1 PLPPR4 USO1 PABPC3 DNAJA2 CLTC NAP1L1 ATP1A2 BSN PGK1 LGI1 DNAH11

5.52e-051431871337142655
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

MPP2 KMT2C LONP1 DNAJA2 UBR4 ASH1L NAP1L1 GPT2 DNAH11

5.78e-0568987936543142
Pubmed

XIAP activity dictates Apaf-1 dependency for caspase 9 activation.

APAF1 XIAP

6.16e-05587217562856
Pubmed

A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis.

APAF1 XIAP

6.16e-05587211242052
Pubmed

Multiple genes encode the human Na+,K+-ATPase catalytic subunit.

ATP1A2 ATP1A4

6.16e-0558723035563
Pubmed

Linkage map of nine loci defined by polymorphic DNA markers assigned to rat chromosome 13.

ATP1A2 F5

6.16e-0558728288230
Pubmed

Clathrin anchors deubiquitinating enzymes, AMSH and AMSH-like protein, on early endosomes.

HGS CLTC

6.16e-05587216716190
Pubmed

MVH in piRNA processing and gene silencing of retrotransposons.

PIWIL4 TDRD1

6.16e-05587220439430
Pubmed

Apoptosis is involved in maintaining the character of the midbrain and the diencephalon roof plate after neural tube closure.

SOX1 APAF1

6.16e-05587232979334
Pubmed

Systematic proteomics of endogenous human cohesin reveals an interaction with diverse splicing factors and RNA-binding proteins required for mitotic progression.

USO1 SUPT6H UBR4 CLTC RXFP1 MAU2

6.43e-0527287631010829
Pubmed

The Deubiquitinating Enzyme USP48 Interacts with the Retinal Degeneration-Associated Proteins UNC119a and ARL3.

MPP2 PABPC3 DNAJA2 CLTC NAP1L1 RGS9 PGK1 NOMO1

7.45e-0555287836293380
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

BPTF KMT2C USF3 SUPT6H TUSC3 FRMPD2 ASH1L XIAP DENND5A GPT2 KDM6A VPS13B PPP4R4

8.25e-051489871328611215
Pubmed

The family of human Na+,K+-ATPase genes. No less than five genes and/or pseudogenes related to the alpha-subunit.

ATP1A2 ATP1A4

9.22e-0568723036582
Pubmed

Essential postmitochondrial function of p53 uncovered in DNA damage-induced apoptosis in neurons.

APAF1 XIAP

9.22e-05687217218959
Pubmed

Prothrombotic phenotype of protein Z deficiency.

SERPINA10 F5

9.22e-05687210829076
Pubmed

Modification of gene products involved in resistance to apoptosis in metastatic colon cancer cells: roles of Fas, Apaf-1, NFkappaB, IAPs, Smac/DIABLO, and AIF.

APAF1 XIAP

9.22e-05687217603079
Pubmed

Na,K-ATPase alpha- and beta-isoform expression in developing skeletal muscles: alpha(2) correlates with t-tubule formation.

CACNA1S ATP1A2

9.22e-05687212397396
Pubmed

A role for Fkbp6 and the chaperone machinery in piRNA amplification and transposon silencing.

PIWIL4 TDRD1

9.22e-05687222902560
Pubmed

The E3 ligase PARC mediates the degradation of cytosolic cytochrome c to promote survival in neurons and cancer cells.

APAF1 XIAP

9.22e-05687225028717
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

MPP1 USO1 DYNC2H1 SUPT6H DNAJA2 FN3KRP CLTC BSN

1.15e-0458887838580884
Pubmed

Differential involvement of Na(+),K(+)-ATPase isozymes in preimplantation development of the mouse.

ATP1A2 ATP1A4

1.29e-04787210837135
Pubmed

GPAT2 is required for piRNA biogenesis, transposon silencing, and maintenance of spermatogonia in mice†.

PIWIL4 TDRD1

1.29e-04787230951587
Pubmed

Molecular genetics of Na,K-ATPase.

ATP1A2 ATP1A4

1.29e-0478722158121
Pubmed

Regulation of cargo transfer between ESCRT-0 and ESCRT-I complexes by flotillin-1 during endosomal sorting of ubiquitinated cargo.

HGS CLTC

1.29e-04787228581508
Pubmed

Mouse GTSF1 is an essential factor for secondary piRNA biogenesis.

PIWIL4 TDRD1

1.29e-04787229437694
Pubmed

Cell cycle-related kinase is a crucial regulator for ciliogenesis and Hedgehog signaling in embryonic mouse lung development.

WDR19 DYNC2H1 DNAH11

1.40e-044087332317081
Pubmed

Protein interactome mining defines melatonin MT1 receptors as integral component of presynaptic protein complexes of neurons.

KMT2C MTMR6 DYNC2H1 UBR4 NAP1L1 CDH4

1.62e-0432287626514267
Pubmed

The endonuclease activity of Mili fuels piRNA amplification that silences LINE1 elements.

PIWIL4 TDRD1

1.72e-04887222020280
Pubmed

Tdrkh is essential for spermatogenesis and participates in primary piRNA biogenesis in the germline.

PIWIL4 TDRD1

1.72e-04887223714778
Pubmed

Nicalin and its binding partner Nomo are novel Nodal signaling antagonists.

NCLN NOMO1

1.72e-04887215257293
Pubmed

Four enzymes cooperate to displace histone H1 during the first minute of hormonal gene activation.

BPTF KMT2C

1.72e-04887221447625
Pubmed

Skirting the pitfalls: a clear-cut nomenclature for H3K4 methyltransferases.

KMT2C ASH1L

1.72e-04887223130995
Pubmed

Mili interacts with tudor domain-containing protein 1 in regulating spermatogenesis.

PIWIL4 TDRD1

1.72e-04887219345100
Pubmed

UTX deficiency in neural stem/progenitor cells results in impaired neural development, fetal ventriculomegaly, and postnatal death.

SOX1 KDM6A

1.72e-04887236412518
Pubmed

Knockdown of miR-182 promotes apoptosis via regulating RIP1 deubiquitination in TNF-α-treated triple-negative breast cancer cells.

APAF1 XIAP

1.72e-04887227476169
Pubmed

Tagging genes with cassette-exchange sites.

BPTF KMT2C UTP25 UBR4 RFX7 AQR

2.00e-0433587615741177
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

LONP1 USO1 SUPT6H DNAJA2 UBR4 CLTC NAP1L1 NOMO1

2.01e-0463887833239621
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

WDR19 DYNC2H1 UBR4 NCLN BSN KDM6A PPP4R4 DNAH11

2.01e-0463887831182584
Pubmed

Genomic analysis of mouse retinal development.

MPP2 MPP4 CELF3 HGS RGS9 MAU2 NCLN BSN CDH4 NOMO1

2.09e-041006871015226823
Pubmed

SARA and RNF11 interact with each other and ESCRT-0 core proteins and regulate degradative EGFR trafficking.

HGS CLTC

2.20e-04987223222715
Pubmed

Activated Cdc42-associated kinase 1 is a component of EGF receptor signaling complex and regulates EGF receptor degradation.

HGS CLTC

2.20e-04987217182860
Pubmed

XIAP associates with GSK3 and inhibits the promotion of intrinsic apoptotic signaling by GSK3.

APAF1 XIAP

2.20e-04987219698783
Pubmed

Substrate-driven assembly of a translocon for multipass membrane proteins.

NCLN NOMO1

2.20e-04987236261522
Pubmed

MITOPLD is a mitochondrial protein essential for nuage formation and piRNA biogenesis in the mouse germline.

PIWIL4 TDRD1

2.20e-04987221397847
Pubmed

Alterations in the brain interactome of the intrinsically disordered N-terminal domain of the cellular prion protein (PrPC) in Alzheimer's disease.

USO1 DNAJA2 HGS CLTC ATP1A2 BSN

2.20e-0434187629791485
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

BPTF LONP1 SUPT6H DNAJA2 UBR4 NAP1L1 MAU2 KDM6A PGK1 AQR

2.23e-041014871032416067
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

BPTF LONP1 SUPT6H GET3 CLTC NAP1L1 NCLN F5 PGK1 AQR

2.41e-041024871024711643
Pubmed

CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.

BPTF USO1 DNAJA2 FN3KRP CLTC NAP1L1 PGK1

2.45e-0449487726831064
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

BPTF PABPC3 UBR4 CLTC ASH1L PKHD1 ATP1A2 BSN ATP1A4 PGK1 PPP4R4 CCDC148

2.47e-041442871235575683
Pubmed

Proteomic analysis of murine Piwi proteins reveals a role for arginine methylation in specifying interaction with Tudor family members.

PIWIL4 TDRD1

2.75e-041087219584108
Pubmed

Sleeping Beauty mutagenesis reveals cooperating mutations and pathways in pancreatic adenocarcinoma.

KMT2C KDM6A

2.75e-041087222421440
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

WDR19 DYNC2H1 SUPT6H DNAJA2 UBR4 HGS CLTC APAF1 NCLN VPS13B AQR NOMO1

3.26e-041487871233957083
Pubmed

A Single Adaptable Cochaperone-Scaffold Complex Delivers Nascent Iron-Sulfur Clusters to Mammalian Respiratory Chain Complexes I-III.

MPP1 MPP2 NLN DNAJA2 FN3KRP SFXN2 MMUT NOMO1

3.27e-0468687828380382
Pubmed

Ubiquitin-specific protease 8 deubiquitinates Sec31A and decreases large COPII carriers and collagen IV secretion.

HGS CLTC

3.35e-041187229604273
Pubmed

The IFT-A complex regulates Shh signaling through cilia structure and membrane protein trafficking.

WDR19 DYNC2H1

3.35e-041187222689656
Pubmed

Impact of promoter polymorphisms in key regulators of the intrinsic apoptosis pathway on the outcome of childhood acute lymphoblastic leukemia.

APAF1 XIAP

3.35e-041187224038028
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

WDR19 KMT2C PLPPR4 SUPT6H ATP1A2 BSN PADI2

3.71e-0452987714621295
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

PLPPR4 UBR4 PER1

3.81e-04568739455484
Pubmed

New nomenclature for chromatin-modifying enzymes.

KMT2C ASH1L KDM6A

4.01e-045787318022353
Pubmed

Clathrin-dependent mechanisms modulate the subcellular distribution of class C Vps/HOPS tether subunits in polarized and nonpolarized cells.

HGS CLTC

4.02e-041287221411634
Pubmed

Cytoplasmic compartmentalization of the fetal piRNA pathway in mice.

PIWIL4 TDRD1

4.02e-041287220011505
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

BPTF KMT2C SUPT6H NAP1L1 KDM6A

4.29e-0425187531076518
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

MPP1 UBR4 SYK ITGAX

4.68e-0414387430397336
Pubmed

Transcription mapping and expression analysis of candidate genes in the vicinity of the mouse Loop-tail mutation.

ATP1A2 ATP1A4

4.74e-041387210920231
Pubmed

Maturation of the olfactory sensory neurons by Apaf-1/caspase-9-mediated caspase activity.

APAF1 BSN

4.74e-041387220624980
Pubmed

The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.

DYNC2H1 DNAH11

4.74e-041387217884984
Pubmed

Demethylation of H3K27 regulates polycomb recruitment and H2A ubiquitination.

KMT2C KDM6A

4.74e-041387217761849
Pubmed

Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development.

KMT2C ASH1L

4.74e-041387224619213
Pubmed

Nociceptor-derived Reg3γ prevents endotoxic death by targeting kynurenine pathway in microglia.

TRPA1 XIAP

4.74e-041387235263589
Pubmed

Multiple loci influencing hippocampal degeneration identified by genome scan.

F5 VPS13B

4.74e-041387222745009
Pubmed

A comparison of the properties of Sox-3 with Sry and two related genes, Sox-1 and Sox-2.

SOX1 PGK1

4.74e-04138728625802
Pubmed

Global proteomics of Ubqln2-based murine models of ALS.

MTMR6 DNAJA2 FN3KRP HGS XIAP

5.13e-0426187533277362
Pubmed

The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.

USO1 DNAJA2 GET3 NAP1L1 PGK1 AQR

5.14e-0440087635013556
Pubmed

The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.

LONP1 USO1 GET3 SFXN2 PGK1

5.22e-0426287536880596
CytobandEnsembl 112 genes in cytogenetic band chr16q11

DNAJA2 GPT2

2.31e-0412872chr16q11
Cytoband16q12.1

DNAJA2 GPT2

1.91e-033487216q12.1
Cytoband1q23.2

ATP1A2 ATP1A4

2.03e-03358721q23.2
GeneFamilyPDZ domain containing

MPP1 MPP2 SYNPO2 MPP4 FRMPD2 APBA1

8.15e-061525761220
GeneFamilyCalcium voltage-gated channel subunits|Membrane associated guanylate kinases

MPP1 MPP2 MPP4

7.34e-0526573904
GeneFamilyATPase Na+/K+ transporting subunits

ATP1A2 ATP1A4

2.03e-0475721208
GeneFamilyPHD finger proteins

BPTF KMT2C ASH1L

2.87e-039057388
ToppCell3'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

NAALAD2 MPP4 APBA1 COX4I2 ATP1A2 DNAH11

1.82e-06187876150023e6a50c9da461f2321074d2d5e96caafb06
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

BPTF USF3 CLTC XIAP VPS13B AQR

2.18e-06193876abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_hypoxia-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MPP1 KMT2C UBR4 SYK DENND5A ITGAX

2.60e-06199876379bbd9cecf466b902411c54d74bd9885285b1ba
ToppCell368C-Myeloid-Macrophage-FABP4+_Macrophage|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

MYO7B CD101 TUSC3 RGS9 CTSE

1.26e-051538759f0607a88d5f8a2c128a2ff64dfbc986212f13b2
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D122|Adult / Lineage, Cell type, age group and donor

MPP2 SYNPO2 NAALAD2 COX4I2 ATP1A2

1.56e-05160875fd14dfeb7021a4b7299371854dc8fc1fd66c8dae
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_myocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPA1 PKHD1 ATP1A4 PPP4R4 SMPX

1.56e-0516087541d6c811c445c0ba9b6a2deb10a3b6b793172582
ToppCellfacs-Heart-RV-24m-Mesenchymal-atrial_cardiomyocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPA1 PKHD1 ATP1A4 PPP4R4 SMPX

1.56e-05160875c1d03c0ac9c12615a06499209fcdf18e9b6f1fba
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 PIWIL4 RGS9 RXFP1

1.97e-051688757abaddbcc55e44653d54aa15464266aa6bd5c9d2
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 PIWIL4 RGS9 RXFP1

2.09e-05170875417b77c12a7982b1ce4b4bc57f30335d261220f5
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 PIWIL4 RGS9 RXFP1

2.27e-0517387595c723b09254ae7131fe5ba0841472502e83269b
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 PIWIL4 RGS9 RXFP1

2.34e-05174875e4d65fe121a32ac4cdd6312e7b8f867f0852e991
ToppCellPericytes-IPF_01|World / lung cells shred on cell class, cell subclass, sample id

SYNPO2 NAALAD2 PLPPR4 COX4I2 ATP1A2

2.40e-05175875ddf721023a7afc8085c5de17aa254a6575444c0f
ToppCellfacs-Marrow-T_cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D APBA1 PIWIL4 ITGAX PADI2

2.47e-0517687574f851a398c7562dd713bc0d8d488c0037243112
ToppCelldroplet-Kidney-nan-18m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPPR4 RGS9 SERPINA10 CDH4 PPP4R4

2.47e-05176875533d544852038c0612aacf87f4b1c88ff7aace82
ToppCellfacs-Marrow-T_cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D APBA1 PIWIL4 ITGAX PADI2

2.47e-0517687531b5459a978d5cdde0af03a77401e0464d8c95ba
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPPR4 RGS9 SERPINA10 BSN APOBEC4

2.60e-05178875a74e5a390cbeaca9de1fdb7b2a0e50783bd202dd
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPPR4 RGS9 SERPINA10 BSN APOBEC4

2.60e-051788751bddbc083c36657bd6910f7466126ab325e88176
ToppCell10x_3'_v3-blood_(10x_3'_v3)-myeloid-myeloid_granulocytic-granulocyte|blood_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

WDR19 NAALAD2 APBA1 GPT2 DNAH11

2.67e-05179875140dd7dbac48f5f07279f31bf971d7fbd41fa18b
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 TOX RGS9 RXFP1

2.75e-05180875b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCell5'-Adult-SmallIntestine-Mesenchymal-myocytic-myofibroblast|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 TRPA1 APBA1 RGS9 ATP1A2

2.82e-05181875fc51468c74534b60b4e786bd512d0f1c5dc05de7
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 TOX RGS9 RXFP1

2.82e-0518187508f44323bf71b6004a921bbc969c954c75feeb66
ToppCellfacs-Marrow-B-cells-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D SEC61G APBA1 ITGAX PADI2

2.82e-05181875782716b8b1d447d2bbe09a693fa5ed7ebeac0efb
ToppCellfacs-Marrow-B-cells-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D SEC61G APBA1 ITGAX PADI2

2.82e-05181875e2481291c236105774c53883e6f20da11941df9b
ToppCellCiliated_cells-B-Donor_04|World / lung cells shred on cell class, cell subclass, sample id

DYNC2H1 FRMPD2 APOBEC4 DNAH11 CCDC148

2.90e-05182875e93968f800bfeb258e4e834fc8bf92d1cb72cd73
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

PALD1 TOX APAF1 APBA1 PADI2

3.05e-0518487542d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCell5'-Adult-LargeIntestine-Mesenchymal-Pericytes-Pericyte|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 PLPPR4 COX4I2 ATP1A2 DNAH11

3.21e-051868750c477016c1b539b3086a8066c3c6443f08c222a3
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DOCK3 SYNPO2 TOX ATP1A2 CDH4

3.38e-051888753177b2c1723268d330d3e9f24f9e24492ace6286
ToppCelldroplet-Kidney-nan-21m-Epithelial-kidney_mesangial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A12 SYNPO2 COX4I2 ATP1A2 LGI1

3.56e-051908751803b1e7c36285f9eaabc3c6e9a9752c5908db3d
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 RXFP1 COX4I2 ITIH5 DNAH11

3.56e-051908755681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellfacs-Heart-LV-3m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SEC24D NAALAD2 COX4I2 ATP1A2 ITIH5

3.65e-05191875b7a57691a4742070cee640e285c1f4d0da95baf1
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

PALD1 TOX APAF1 APBA1 PADI2

3.74e-05192875bd3d00b094d92463b06023361a71240851a542b8
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DOCK3 SYNPO2 PLPPR4 COX4I2 ATP1A2

3.83e-05193875000b9e6a819b94ea2e6e9173daf97ba9ac2b6cc6
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_D_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 TRPA1 TOX RGS9 F5

3.83e-051938757fcfb0f76789fa8d8caa18304cb43c8fd899a81b
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C DYNC2H1 CELF3 CLTC ASH1L

4.02e-051958753e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KMT2C DYNC2H1 CELF3 CLTC ASH1L

4.02e-051958757796ea9247f4c63762f0de8490fed08b9717fa23
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAALAD2 ASH1L ATP1A2 ITIH5 SMPX

4.02e-051958755c86fddd6d0530beecf45ea5ba6b823123847696
ToppCellcritical-Epithelial-Ciliated|critical / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNC2H1 TUSC3 FRMPD2 APOBEC4 DNAH11

4.12e-0519687527b855c6e1ae44f16db998cf0e81bd686b9cee7e
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-Pericyte-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

SYNPO2 COX4I2 ATP1A2 TDRD1 ITIH5

4.12e-0519687512d9028f90c057c6e5cff00301793fa550e86c5a
ToppCellMonocytes-cDCs|World / Immune cells in Kidney/Urine in Lupus Nephritis

PALD1 APBA1 SYK ITGAX PADI2

4.22e-051978753388c104af4c6a05988e102627e0c5e34d9dcc45
ToppCellE16.5-Mesenchymal-Mesenchymal_myocytic|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 NAALAD2 COX4I2 CDH4 SMPX

4.22e-05197875e132f4b9deef6a565262c0aa0863cafe28f248e6
ToppCellcritical-Epithelial-Ciliated|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DYNC2H1 TUSC3 FRMPD2 APOBEC4 DNAH11

4.33e-05198875ee2c8385c0bf4ea9f5c9517b52cf131af3fbdd40
ToppCellParenchymal-10x3prime_v2-Immune_Myeloid-Macrophage_other-Macro_CHIT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

MPP1 SYK ATP1A4 ITGAX PADI2

4.33e-05198875243109377d62d20c69e9d1fedc252156e90cda1e
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 NAALAD2 COX4I2 ITIH5 SMPX

4.33e-05198875b258f672529fb2c03e62e2696d335043c4963280
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MPP2 DOCK3 SYNPO2 ATP1A2 ITIH5

4.33e-05198875d1827e3707b929e3a3562989a0c11537d344e164
ToppCellBronchial-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

MPP1 DOCK3 NLN SYK ITGAX

4.33e-051988750b41b3d6c2db795320e8b65d40d85fb8b618cc34
ToppCellBronchus_Control_(B.)-Stromal-TX-Smooth_muscle-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

SYNPO2 COX4I2 ATP1A2 CDH4 ITIH5

4.43e-051998752c5ad62919c64ea0242e0984bb9932d2d975f4e3
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MPP1 UBR4 PER1 ITGAX PGK1

4.54e-05200875851c57187db8bc91a393655bca5f13e787a723d4
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal|6m / Sample Type, Dataset, Time_group, and Cell type.

CACNA1S SLC39A12 F5 SMPX DNAH11

4.54e-0520087513ec8afea86e4a10599c924871ba4e325b0a8013
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Hematologic-erythrocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP1 SEC61G FN3KRP CTSE

9.93e-0512387489415e47db7352ba385895e2127e683db131dc03
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Ductal_and_Papillary_Carcinoma-1|TCGA-Breast / Sample_Type by Project: Shred V9

TRPA1 PLPPR4 DNAJA2 MUC2

1.68e-04141874330f944b38c3170dfc79ab033fae7b9ab71e840d
ToppCellP07-Hematopoietic-Immune-immune_cell_unspecified|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD101 CTSE ITGAX PADI2

1.82e-04144874eb057dbdb2a5a2d29b93e5ed5479a3fd1bf3fd26
ToppCellP07-Hematopoietic-Immune|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CD101 CTSE ITGAX PADI2

1.82e-04144874962698c5c15bd583fccda0593b7aab5f2eb4bc9f
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma-2|TCGA-Pancreas / Sample_Type by Project: Shred V9

MPP2 SERPINA10 BSN PPP4R4

1.92e-04146874bc2adef529d0bbfcccef7435401a47a6ffcc1832
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Neuroendocrine_Carcinoma|TCGA-Pancreas / Sample_Type by Project: Shred V9

MPP2 SERPINA10 BSN PPP4R4

1.92e-0414687472c1e7e0c2b6ff6c4084af61fa19c2b8eab16eda
ToppCell356C-Lymphocytic-NK_cells-NK_cell_D2|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MPP2 PALD1 CD101 ATP1A4

2.36e-041548748dc8f02534c3ebda30bf9e702e36d0c53d89e5a5
ToppCellfacs-Brain_Non-Myeloid-Striatum-24m|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RGS9 SERPINA10 APOBEC4 DNAH11

2.66e-0415987400a157d033627d0e65c3fbd38d652c4cf56b47f6
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-24m-Lymphocytic-B_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK3 CACNA1S SYK ATP1A4

2.73e-041608746bafbe2b4b98bc088406a516d079093f89d9c344
ToppCelldroplet-Spleen-nan-24m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX ITGAX PADI2 ITIH5

2.99e-041648747a51365bad2910c130bd952805f7a1bef51be481
ToppCellThalamus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Slc17a6-Rora-Excitatory_Neuron.Slc17a6.Rora.Cbln2_(Neuron.Slc17a6.Rora.Cbln2)|Thalamus / BrainAtlas - Mouse McCarroll V32

SERPINA10 RXFP1 TDRD1

3.06e-04678735202166895fd109ad0d7584fc35c74814a59ce2b
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX ITGAX PADI2 ITIH5

3.06e-04165874e24621c8d4dbafb407033d832fe9337f13feae34
ToppCellwk_08-11-Mesenchymal-Fibroblast-Alveolar_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

PLPPR4 MAU2 VPS13B ITIH5

3.13e-0416687465dafed953b01a9830b54309af75c7a561e88336
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

MPP2 CELF3 GPT2 F5

3.21e-04167874c87ebfa8c3284ad33579190e148c95bcaf670d17
ToppCellPND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SYNPO2 FN3KRP RXFP1 SMPX

3.21e-0416787491b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX ITGAX PADI2 ITIH5

3.21e-04167874aef22535a76e93472bcedacbb2c6991f3c9c8cd5
ToppCelltumor_Lymph_Node_/_Brain-Myeloid_cells-Pleural_Mac|Myeloid_cells / Location, Cell class and cell subclass

GET3 RANBP6 PRR14L MAU2

3.28e-041688748697b40b2ec2cce68ef3beb4792eb3eff29be053
ToppCelldroplet-Thymus-nan-24m-Lymphocytic-double_negative_T_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX USO1 RANBP6 SMPX

3.28e-04168874de1042267407719f19eb3f580a5df0c9cd0e8273
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-pericyte_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 SYNPO2 SERPINA10 COX4I2

3.35e-041698742d23b4cee060f8adddc430c1c10d4e25205b4af6
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 SYNPO2 SERPINA10 COX4I2

3.35e-04169874ecaf08e8e0b54d1c97a02bc1f65409fd43d68227
ToppCellfacs-Lung-Endomucin-3m-Mesenchymal|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 SYNPO2 SERPINA10 COX4I2

3.35e-04169874ad6af6609acf158cb79e45ee7ca9af332be3c40c
ToppCell3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.0.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DYNC2H1 TDRD1 DNAH11 CCDC148

3.35e-0416987414aadc2d1bf66eb47dac33b4d61ddb3c942caa4f
ToppCellPND01-03-samps-Mesenchymal-Pericyte-pericyte_F|PND01-03-samps / Age Group, Lineage, Cell class and subclass

MPP2 PALD1 NAALAD2 COX4I2

3.43e-0417087471718dcebd48105994c313bb55babc70301170a0
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2-Exc_L6_FEZF2_KRT17|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 PIWIL4 RXFP1

3.43e-0417087484d49a1f2989d98bd0acf9ec2d59f1042fc0f55b
ToppCelldroplet-Liver-LIVER-NPC-1m-Lymphocytic-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX FN3KRP BSN PADI2

3.43e-04170874bcbe5c44ef708c5f01dc7dd9aec7b436e1a62d56
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_LCN15|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TOX FRMPD2 PIWIL4 RXFP1

3.51e-041718749e00c8191ca9d52151a49baf39f8581cb176fb76
ToppCelldroplet-Thymus-nan-3m-Myeloid|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A12 NAALAD2 APBA1 ITGAX

3.51e-0417187425493a4a7b636920e2cfd984542cc500709c9dcf
ToppCelldroplet-Thymus-nan-3m-Myeloid-professional_antigen_presenting_cell|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A12 NAALAD2 APBA1 ITGAX

3.51e-04171874508b41e3ad2638f9dd546d251b13ff60fc8c3207
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell|Adult / Lineage, Cell type, age group and donor

SYNPO2 PLPPR4 COX4I2 ATP1A2

3.59e-04172874c62cad0f4212d1e9ea1ec3143ad3c4e06aff0ebf
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT2_L6_FEZF2|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 PIWIL4 RXFP1

3.59e-04172874cecfe5cf20f317ea01b4604789e07a14481c4cd6
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S TRPA1 PLPPR4 APAF1

3.59e-0417287448d0cfc37d1b1ae48ed8f8b2711abeb609d2bb6e
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NAALAD2 RXFP1 ATP1A4 CDH4

3.66e-04173874ab6d3507301038f944ad59ccd848b5e6eeb76d04
ToppCelldroplet-Kidney-KIDNEY-1m-Lymphocytic-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TOX ATP1A2 RFX7 PADI2

3.66e-04173874de124fb7ded04664d4184bf12f1f201c0784f07c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Classical_Dendritic_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

TOX APBA1 SYK ITGAX

3.66e-0417387473f858f2c45d19b9ec8d99ac02c91551790f670c
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD101 SEC61G ITGAX PADI2

3.66e-04173874513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCelldroplet-Thymus-nan-3m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC39A12 NAALAD2 APBA1 ITGAX

3.66e-0417387463f03abca84ae021ff34ff34537838aa8a1ccd11
ToppCell5'-Adult-Appendix-Mesenchymal-myocytic|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SYNPO2 TRPA1 PLPPR4 LGI1

3.66e-04173874f8e3dded726bb3a6c24bfedf8c6732bb46262308
ToppCell356C-Myeloid-Macrophage-SPP1+_Macrophage_4|356C / Donor, Lineage, Cell class and subclass (all cells)

MPP1 DOCK3 ATP1A4 TDRD1

3.75e-0417487475b3a852140fb726025c3c987143d67944afde2d
ToppCellmetastatic_Brain-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

MYO7B NAP1L1 COX4I2 GPT2

3.75e-041748745ec8a48a390379d6c422120dce46437a77da67cc
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 RGS9 RXFP1

3.83e-0417587490e29945aa861082c94bb4f331161adc3a6ef899
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S SEC24D GPT2 CTSE

3.83e-0417587428b29f844fa46fe579ddc19039fb2d9dc5f48f3b
ToppCell5'-Adult-Distal_Rectal-Epithelial-goblet-BEST2+_Goblet_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CELF3 SEC61G NCLN MUC2

3.83e-04175874019ea30ac55748463d7917abf3d3f0e804189bfd
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-plasma_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CACNA1S SEC24D GPT2 CTSE

3.83e-04175874ac96ca9ca309b0d72a2f5af6a3b02c7f80755750
ToppCellThalamus-Neuronal-Excitatory|Thalamus / BrainAtlas - Mouse McCarroll V32

CELF3 APBA1 BSN PPP4R4

3.91e-04176874d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 RXFP1 PPP4R4

3.91e-041768740710689e66deba179b0a8038cdd56b4834984f12
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_5-Exc_L4-5_RORB_LINC01474|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

TRPA1 TOX FRMPD2 TDRD1

3.91e-04176874cd4b9211652596c42e7af318bcd464681daebb10
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 RGS9 RXFP1

3.91e-0417687472a2a01618ce836bc843395d5095e9090759b4a6
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 RGS9 RXFP1

3.91e-04176874e4b21fd6a5e0c5950f27c3e1868318e48330ae5e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 COX4I2 ATP1A2 DNAH11

4.00e-041778744943d040eee0f9dceaddc7498171281d170e271f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

SYNPO2 COX4I2 ATP1A2 DNAH11

4.00e-041778743f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

SEC24D SYNPO2 RXFP1 PPP4R4

4.00e-04177874f30d757ee8db7e10d547498dab6560473c6ed7c0
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

RXFP1 COX4I2 ITIH5 DNAH11

4.00e-04177874a8625d14682183cf77cb51eaf11bc15a3528f586
DiseaseTinnitus

MPP2 APAF1 APBA1 PKHD1 ITGAX

4.25e-05130875HP_0000360
DiseaseHypokalemic periodic paralysis

CACNA1S ATP1A2

5.14e-054872C0238358
DiseaseJeune thoracic dystrophy

WDR19 DYNC2H1

5.14e-054872cv:C0265275
Diseaseaspartate aminotransferase, cytoplasmic measurement

SERPINA10 PPP4R4

8.54e-055872EFO_0008031
Diseaseadenoid cystic carcinoma (is_implicated_in)

KMT2C KDM6A

8.54e-055872DOID:0080202 (is_implicated_in)
Diseasefamilial hemiplegic migraine (implicated_via_orthology)

ATP1A2 ATP1A4

1.79e-047872DOID:0060178 (implicated_via_orthology)
DiseaseCarcinoma, Transitional Cell

KMT2C APAF1 KDM6A

2.43e-0441873C0007138
Diseasealpha-1-antitrypsin measurement

SERPINA10 PPP4R4

3.05e-049872EFO_0008327
DiseaseCiliopathies

WDR19 DYNC2H1 PKHD1 DNAH11

3.21e-04110874C4277690
DiseaseJeune thoracic dystrophy

WDR19 DYNC2H1

4.65e-0411872C0265275
Diseaseabdominal adipose tissue measurement

CACNA1S PKHD1 ATP1A4

5.21e-0453873EFO_0803316
Diseasenervous system disease (implicated_via_orthology)

ATP1A2 ATP1A4

5.56e-0412872DOID:863 (implicated_via_orthology)
Diseasesquamous cell carcinoma, multiple keratinocyte carcinoma susceptibility measurement, basal cell carcinoma

PALD1 PKHD1

6.56e-0413872EFO_0000707, EFO_0004193, EFO_0007932
Diseasedual specificity mitogen-activated protein kinase kinase 2 measurement

SERPINA10 PPP4R4

1.00e-0316872EFO_0008112
Diseaseprotein Z-dependent protease inhibitor measurement

SERPINA10 PPP4R4

1.28e-0318872EFO_0021849
Diseaseepilepsy (implicated_via_orthology)

ATP1A2 BSN ATP1A4 LGI1

1.40e-03163874DOID:1826 (implicated_via_orthology)
DiseaseDeep Vein Thrombosis

SERPINA10 F5

1.74e-0321872C0149871
DiseaseVenous Thrombosis

SERPINA10 F5

1.74e-0321872C0042487
Diseasebody weight loss

PKHD1 CDH4

1.91e-0322872EFO_0005245
Diseasebeta-amyloid 1-42 measurement

NLN LGI1 CCDC148

2.19e-0387873EFO_0004670

Protein segments in the cluster

PeptideGeneStartEntry
MSVKSPFNVMSRNNL

TDRD1

1

Q9BXT4
MGQQPITFLRQVMAL

GPT2

101

Q8TD30
EPTQQQRAAMLIKMI

APAF1

46

O14727
QLQMKPMSNRERNFV

ASH1L

2346

Q9NR48
LRRMQQVATQLGMFS

CELF3

181

Q5SZQ8
QVAVVAQFDPVRMMS

CCDC148

496

Q8NFR7
IVRHLNMPQMSFQET

APOBEC4

316

Q8WW27
NPQSFLTAIMQTMAR

DNAH11

4381

Q96DT5
EVQIIKNMPQMANFV

AQR

1351

O60306
QLMQAAMPNGTVQRF

BPTF

2321

Q12830
MQNQRVLVTSVPHAM

RGS9

36

O75916
NFATMMNFVRAVISQ

ITGAX

166

P20702
RQLTVQMMQNPQILA

NAP1L1

36

P55209
MAAVPQDVVRQFMEI

NCLN

116

Q969V3
PMEQFQVIQSFLRMV

PALD1

351

Q9ULE6
QMVSSDVLQMFLPQR

FAM189A1

201

O60320
QMQAMIRQRSEPFFP

KMT2C

3071

Q8NEZ4
RKAFAPIQEMMTFVQ

nan

266

A8MVJ9
QMQIPAAAFITNFTM

ITIH5

86

Q86UX2
VFYARQRIQPQMDMV

FN3KRP

166

Q9HA64
LHPRQSVFNIIMNMN

MTMR6

506

Q9Y217
ANVMQQLDNPYIVRM

SYK

421

P43405
AMQNIVPASQRAVMS

ATAD2B

656

Q9ULI0
QFVLMQQHQMRPTGV

KDM6A

501

O15550
MASSVFMAQQKQPVV

BSN

1736

Q9UPA5
GVTPVFDNMMAQNLV

CTSE

196

P14091
NADQRVMMTYQVPSR

PER1

1136

O15534
MPMQVQVQVNRQAVA

MUC2

4556

Q02817
LTVTNRPMMDVAFVQ

NOMO1

486

Q15155
DPPVNSQQMVYVRAM

MPP4

236

Q96JB8
QMMQAGQRVVDNPIY

LONP1

316

P36776
VIMVLWFMQQNVFVP

MPP2

51

Q14168
MRVDFNVPMKNNQIT

PGK1

21

P00558
ARAFFPNMVNMIVLD

PADI2

581

Q9Y2J8
EYMQRMASVRAVPNQ

PABPC3

381

Q9H361
IRQLAPGMVQQMQSV

DNAJA2

171

O60884
RPMMLQSALAFEQII

DYNC2H1

636

Q8NCM8
MDSFKNMVPQQALVI

ATP1A2

156

P50993
MSRQPQVMLTNTFDL

CD101

546

Q93033
FQQRMLSEFPQAVAM

DOCK3

1386

Q8IZD9
VMANQRPLQFAEIEM

CACNA1S

1621

Q13698
GFTFNMAVRMIQNSP

FRMPD2

836

Q68DX3
RAFMLTVMVSNQAPL

CDH4

466

P55283
TPSKNVRMMQAQEAV

APBA1

476

Q02410
TQIMQIPRNVLEMTF

DENND5A

986

Q6IQ26
MQIKNQISPFISQMC

GET3

191

O43681
NQQSRLPALQMFMRA

MPP1

151

Q00013
VQTQRPWMMFLLQNF

SLC39A12

656

Q504Y0
RESNNMVVPAMQLAS

MAU2

516

Q9Y6X3
AQQLQRMLDMKVNPV

COX4I2

141

Q96KJ9
PTMQRLFMTQFTQGL

PRR14L

1846

Q5THK1
VVLLMSMVNERQPFV

USO1

366

O60763
VNMQGQVAVRNVPMT

UTP25

551

Q68CQ4
AANCVNIPMMRQQEL

SFXN2

186

Q96NB2
FTIMMTNNVLPVQKA

PPP4R4

531

Q6NUP7
NQRAGMQTPFLIMDR

F5

1891

P12259
MPRFFTEMNRTVQNP

PIWIL4

736

Q7Z3Z4
SSMRQVFCQMQELPQ

SLC26A10

386

Q8NG04
QVRSEPSNMQFFLMK

WDR19

176

Q8NEZ3
ANMSVVLQQFAVMPR

PKHD1

1376

P08F94
VLQQFAVMPRIMAIF

PKHD1

1381

P08F94
ANQDRVKRPMNAFMV

SOX1

46

O00570
AITPKMMVNFVVERN

OR8U3

76

Q8NH85
MMVNFVVERNTIPFH

OR8U3

81

Q8NH85
TNIIAQAVPHILAMM

RANBP6

306

O60518
FFNVKSNLAQPQMMV

SEC24D

496

O94855
MESFKNMVPQQALVI

ATP1A4

166

Q13733
VMRISPDQGQQFAQM

CLTC

521

Q00610
MMAVAALVVNFSQPV

NLN

466

Q9BYT8
PQNMTSQMFSAIAAV

SUPT6H

1556

Q7KZ85
NSQPRIMQVIAMSKQ

PLPPR4

571

Q7Z2D5
MIVMFTALQPQRQCS

TUSC3

86

Q13454
LRNFNMMAPLHIAVQ

TRPA1

126

O75762
FQNPMVQEAIRMGFS

XIAP

371

P98170
TANIQRMVPMNRTAK

SYNPO2

576

Q9UMS6
MDQVMQFVEPSRQFV

SEC61G

1

P60059
MNMSKQPVSNVRAIQ

SMPX

1

Q9UHP9
KQTVQMRAQMPAFPL

HGS

551

O14964
SNIQQRMFRPLMNLS

RXFP1

356

Q9HBX9
MAFLILPRVTQAMQR

SCART1

921

Q4G0T1
LNSAMQVIQMAQPVG

USF3

526

Q68DE3
LTVMMQTAFPNALQK

RFX7

1131

Q2KHR2
VPMNFRNASQAKRLM

SERPINA10

191

Q9UK55
VQQRMIVFSPLFIMR

VPS13B

2836

Q7Z7G8
SVNMDAQMRFVPLIL

UBR4

841

Q5T4S7
NNQMPVTVSIANMAV

TOX

401

O94900
NLMNVSNARRPSSIM

ZNF781

311

Q8N8C0
IVQLLTMKPFTANMQ

BPIFA4P

116

Q86YQ2
QDIQRMPSRGSMVFQ

LGI1

466

O95970
IQVDLNNPIAVRMMN

NAALAD2

641

Q9Y3Q0
MTMNGAVIPVLANFI

MMUT

186

P22033
SQRFGVLLPNAMRMQ

MYO7B

701

Q6PIF6