Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncargo receptor activity

LRP1 LRP2 ENDOU

6.14e-068593GO:0038024
GeneOntologyMolecularFunctioncalcium ion binding

MASP1 LRP1 LRP2 RYR2 FBN1

8.14e-0674995GO:0005509
GeneOntologyMolecularFunctionlow-density lipoprotein particle receptor activity

LRP1 LRP2

2.16e-051692GO:0005041
GeneOntologyMolecularFunctionlipoprotein particle receptor activity

LRP1 LRP2

3.78e-052192GO:0030228
GeneOntologyMolecularFunctionscavenger receptor activity

LRP1 ENDOU

6.30e-052792GO:0005044
GeneOntologyMolecularFunctionlipoprotein particle receptor binding

LRP1 LRP2

1.33e-043992GO:0070325
GeneOntologyMolecularFunctionsulfur compound binding

LRP1 RYR2 FBN1

3.28e-0432393GO:1901681
GeneOntologyMolecularFunctionintegrin binding

FBN1 ITGBL1

2.64e-0317592GO:0005178
GeneOntologyMolecularFunctionserine-type peptidase activity

MASP1 ENDOU

3.67e-0320792GO:0008236
GeneOntologyMolecularFunctionserine hydrolase activity

MASP1 ENDOU

3.85e-0321292GO:0017171
GeneOntologyMolecularFunctionamide binding

LRP1 RYR2

7.51e-0329992GO:0033218
GeneOntologyBiologicalProcesschemoattraction of axon

LRP1 LRP2

1.69e-06592GO:0061642
GeneOntologyBiologicalProcesspositive regulation of lysosomal protein catabolic process

LRP1 LRP2

1.69e-06592GO:1905167
GeneOntologyBiologicalProcesspositive regulation of protein catabolic process in the vacuole

LRP1 LRP2

3.55e-06792GO:1904352
GeneOntologyBiologicalProcessregulation of lysosomal protein catabolic process

LRP1 LRP2

1.11e-051292GO:1905165
GeneOntologyBiologicalProcessregulation of protein catabolic process in the vacuole

LRP1 LRP2

1.54e-051492GO:1904350
GeneOntologyBiologicalProcesslysosomal protein catabolic process

LRP1 LRP2

4.65e-052492GO:1905146
GeneOntologyBiologicalProcesstranscytosis

LRP1 LRP2

4.65e-052492GO:0045056
GeneOntologyBiologicalProcessnegative regulation of cytosolic calcium ion concentration

LRP1 RYR2

5.05e-052592GO:0051481
GeneOntologyBiologicalProcesslipoprotein transport

LRP1 LRP2

6.36e-052892GO:0042953
GeneOntologyBiologicalProcessprotein catabolic process in the vacuole

LRP1 LRP2

6.36e-052892GO:0007039
GeneOntologyBiologicalProcesslipoprotein localization

LRP1 LRP2

6.83e-052992GO:0044872
GeneOntologyBiologicalProcesscardiac chamber development

LRP1 LRP2 RYR2

8.59e-0521293GO:0003205
GeneOntologyBiologicalProcessnegative regulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 LRP2 FBN1

9.33e-0521893GO:0090101
GeneOntologyBiologicalProcessamyloid-beta clearance

LRP1 LRP2

1.31e-044092GO:0097242
GeneOntologyBiologicalProcesscirculatory system development

LRP1 GGNBP2 LRP2 RYR2 FBN1

1.65e-04144295GO:0072359
GeneOntologyBiologicalProcessheart development

LRP1 LRP2 RYR2 FBN1

1.96e-0475794GO:0007507
GeneOntologyBiologicalProcessventricular cardiac muscle tissue morphogenesis

LRP2 RYR2

2.86e-045992GO:0055010
GeneOntologyBiologicalProcessregulation of transmembrane receptor protein serine/threonine kinase signaling pathway

LRP1 LRP2 FBN1

3.68e-0434793GO:0090092
GeneOntologyBiologicalProcesspositive chemotaxis

LRP1 LRP2

4.62e-047592GO:0050918
GeneOntologyBiologicalProcessventricular cardiac muscle tissue development

LRP2 RYR2

4.74e-047692GO:0003229
GeneOntologyBiologicalProcesscardiac muscle tissue morphogenesis

LRP2 RYR2

4.87e-047792GO:0055008
GeneOntologyBiologicalProcessnegative regulation of BMP signaling pathway

LRP2 FBN1

5.25e-048092GO:0030514
GeneOntologyBiologicalProcessaorta development

LRP1 LRP2

5.25e-048092GO:0035904
GeneOntologyBiologicalProcesscoronary vasculature development

LRP1 LRP2

5.65e-048392GO:0060976
GeneOntologyBiologicalProcessregulation of cellular response to growth factor stimulus

LRP1 LRP2 FBN1

6.08e-0441293GO:0090287
GeneOntologyBiologicalProcesstransport across blood-brain barrier

LRP1 LRP2

6.21e-048792GO:0150104
GeneOntologyBiologicalProcessvascular transport

LRP1 LRP2

6.35e-048892GO:0010232
GeneOntologyBiologicalProcesscardiac ventricle morphogenesis

LRP2 RYR2

6.35e-048892GO:0003208
GeneOntologyBiologicalProcessamide transport

LRP1 LRP2 FBN1

6.43e-0442093GO:0042886
GeneOntologyBiologicalProcessretinoid metabolic process

LRP1 LRP2

6.50e-048992GO:0001523
GeneOntologyBiologicalProcesscell adhesion mediated by integrin

FBN1 ITGBL1

6.79e-049192GO:0033627
GeneOntologyBiologicalProcessartery morphogenesis

LRP1 LRP2

6.94e-049292GO:0048844
GeneOntologyBiologicalProcessmuscle tissue morphogenesis

LRP2 RYR2

7.09e-049392GO:0060415
GeneOntologyBiologicalProcessditerpenoid metabolic process

LRP1 LRP2

7.25e-049492GO:0016101
GeneOntologyBiologicalProcesstransforming growth factor beta receptor superfamily signaling pathway

LRP1 LRP2 FBN1

7.61e-0444593GO:0141091
GeneOntologyBiologicalProcessmuscle organ morphogenesis

LRP2 RYR2

8.52e-0410292GO:0048644
GeneOntologyBiologicalProcessterpenoid metabolic process

LRP1 LRP2

9.03e-0410592GO:0006721
GeneOntologyBiologicalProcesscell surface receptor protein serine/threonine kinase signaling pathway

LRP1 LRP2 FBN1

9.59e-0448293GO:0007178
GeneOntologyBiologicalProcessregulation of BMP signaling pathway

LRP2 FBN1

1.40e-0313192GO:0030510
GeneOntologyBiologicalProcessartery development

LRP1 LRP2

1.44e-0313392GO:0060840
GeneOntologyBiologicalProcesscardiac septum development

LRP1 LRP2

1.46e-0313492GO:0003279
GeneOntologyBiologicalProcessregulation of protein transport

LRP1 LRP2 FBN1

1.48e-0356093GO:0051223
GeneOntologyBiologicalProcessnegative regulation of transforming growth factor beta receptor signaling pathway

LRP1 FBN1

1.55e-0313892GO:0030512
GeneOntologyBiologicalProcessisoprenoid metabolic process

LRP1 LRP2

1.69e-0314492GO:0006720
GeneOntologyBiologicalProcessnegative regulation of cellular response to growth factor stimulus

LRP2 FBN1

1.83e-0315092GO:0090288
GeneOntologyBiologicalProcessnegative regulation of catalytic activity

PPP1R11 LRP1 GGNBP2

1.94e-0361593GO:0043086
GeneOntologyBiologicalProcesstube development

LRP1 LRP2 RYR2 FBN1

2.03e-03140294GO:0035295
GeneOntologyBiologicalProcesscardiac chamber morphogenesis

LRP2 RYR2

2.10e-0316192GO:0003206
GeneOntologyBiologicalProcesscardiac ventricle development

LRP2 RYR2

2.10e-0316192GO:0003231
GeneOntologyBiologicalProcessregulation of establishment of protein localization

LRP1 LRP2 FBN1

2.52e-0367493GO:0070201
GeneOntologyBiologicalProcessregulation of transforming growth factor beta receptor signaling pathway

LRP1 FBN1

2.97e-0319292GO:0017015
GeneOntologyBiologicalProcessregulation of cellular response to transforming growth factor beta stimulus

LRP1 FBN1

3.06e-0319592GO:1903844
GeneOntologyBiologicalProcessBMP signaling pathway

LRP2 FBN1

3.13e-0319792GO:0030509
GeneOntologyBiologicalProcesscirculatory system process

LRP1 LRP2 RYR2

3.20e-0373393GO:0003013
GeneOntologyBiologicalProcesscellular response to nitrogen compound

LRP1 RYR2 FBN1

3.44e-0375293GO:1901699
GeneOntologyCellularComponentaxonal growth cone

LRP1 LRP2

1.62e-044592GO:0044295
GeneOntologyCellularComponentclathrin-coated pit

LRP1 LRP2

5.12e-048092GO:0005905
MousePhenoincreased heart left ventricle size

LRP2 RYR2 FBN1

6.94e-0513493MP:0010579
MousePhenoabnormal heart right ventricle morphology

LRP2 RYR2 FBN1

1.09e-0415693MP:0003920
MousePhenoabnormal heart left ventricle size

LRP2 RYR2 FBN1

1.38e-0416993MP:0010578
MousePhenodiaphragmatic hernia

LRP1 FBN1

1.48e-042992MP:0003924
MousePhenoincreased heart ventricle size

LRP2 RYR2 FBN1

1.53e-0417593MP:0008772
MousePhenocardiac hypertrophy

LRP2 RYR2 FBN1

2.14e-0419693MP:0001625
MousePhenooverexpanded pulmonary alveolus

LRP2 FBN1

2.43e-043792MP:0001183
MousePhenoemphysema

LRP2 FBN1

2.43e-043792MP:0001958
MousePhenodecreased survivor rate

MASP1 GGNBP2 RYR2

2.81e-0421593MP:0008770
MousePhenoheart right ventricle hypertrophy

LRP2 FBN1

3.13e-044292MP:0000276
MousePhenoabnormal heart ventricle size

LRP2 RYR2 FBN1

3.35e-0422893MP:0031543
MousePhenoabnormal heart right ventricle wall morphology

LRP2 FBN1

4.81e-045292MP:0031534
MousePhenolethality, incomplete penetrance

MASP1 GGNBP2 RYR2

4.81e-0425893MP:0010831
MousePhenoomphalocele

LRP1 LRP2

4.99e-045392MP:0003052
MousePhenoincreased heart right ventricle size

LRP2 FBN1

5.38e-045592MP:0010563
MousePhenolethality during fetal growth through weaning, complete penetrance

LRP1 GGNBP2 LRP2 RYR2 FBN1

5.64e-04126995MP:0011111
MousePhenoabnormal heart ventricle wall morphology

LRP2 RYR2 FBN1

7.18e-0429693MP:0031532
MousePhenoheart left ventricle hypertrophy

LRP2 RYR2

7.50e-046592MP:0002625
MousePhenoabnormal heart ventricle morphology

LRP1 LRP2 RYR2 FBN1

1.03e-0379394MP:0005294
MousePhenoabnormal diaphragm morphology

LRP1 FBN1

1.08e-037892MP:0002279
MousePhenoabnormal heart right ventricle size

LRP2 FBN1

1.08e-037892MP:0010577
MousePhenoabnormal abdominal wall morphology

LRP1 LRP2

1.19e-038292MP:0003257
MousePhenoabnormal heart left ventricle morphology

LRP2 RYR2 FBN1

1.36e-0336993MP:0003921
MousePhenoabnormal heart electrocardiography waveform feature

MASP1 GGNBP2 RYR2

1.45e-0337793MP:0010508
MousePhenoabnormal heart septum morphology

LRP1 LRP2 RYR2

1.57e-0338893MP:0006113
MousePhenoabnormal impulse conducting system conduction

MASP1 GGNBP2 RYR2

1.72e-0340093MP:0003137
MousePhenoabnormal heart left ventricle wall morphology

LRP2 RYR2

1.73e-039992MP:0031533
MousePhenoenlarged heart

LRP1 LRP2 RYR2 FBN1

1.77e-0391694MP:0000274
MousePhenolethality throughout fetal growth and development

LRP1 GGNBP2 RYR2

2.19e-0343593MP:0006208
MousePhenoabnormal cardiac muscle tissue morphology

LRP2 RYR2 FBN1

3.05e-0348993MP:0010630
MousePhenoabnormal thoracic aorta morphology

LRP2 FBN1

3.14e-0313492MP:0010468
MousePhenoabnormal hypaxial muscle morphology

LRP1 FBN1

3.47e-0314192MP:0003358
MousePhenoabnormal muscle morphology

LRP1 LRP2 RYR2 FBN1

3.55e-03110694MP:0002108
MousePhenocardiac fibrosis

RYR2 FBN1

3.97e-0315192MP:0003141
MousePhenoabnormal body wall morphology

LRP1 LRP2

3.97e-0315192MP:0003385
MousePhenoabnormal heart size

LRP1 LRP2 RYR2 FBN1

4.50e-03118094MP:0005406
MousePhenodecreased respiration

LRP2 FBN1

5.00e-0317092MP:0014274
DomainEGF-like_dom

MASP1 LRP1 LRP2 FBN1 ITGBL1

4.88e-0824995IPR000742
DomainEGF_CA

MASP1 LRP1 LRP2 FBN1

5.19e-088694PF07645
DomainEGF_1

MASP1 LRP1 LRP2 FBN1 ITGBL1

5.50e-0825595PS00022
DomainEGF_2

MASP1 LRP1 LRP2 FBN1 ITGBL1

6.66e-0826595PS01186
DomainEGF_Ca-bd_CS

MASP1 LRP1 LRP2 FBN1

8.44e-089794IPR018097
DomainEGF_CA

MASP1 LRP1 LRP2 FBN1

9.17e-089994PS01187
DomainASX_HYDROXYL

MASP1 LRP1 LRP2 FBN1

9.55e-0810094PS00010
DomainEGF-type_Asp/Asn_hydroxyl_site

MASP1 LRP1 LRP2 FBN1

1.21e-0710694IPR000152
DomaincEGF

LRP1 LRP2 FBN1

2.00e-072693PF12662
DomaincEGF

LRP1 LRP2 FBN1

2.00e-072693IPR026823
DomainEGF_CA

MASP1 LRP1 LRP2 FBN1

2.13e-0712294SM00179
DomainEGF-like_Ca-bd_dom

MASP1 LRP1 LRP2 FBN1

2.27e-0712494IPR001881
DomainEGF

LRP1 LRP2 FBN1 ITGBL1

2.93e-0623594SM00181
DomainEGF_3

MASP1 LRP1 LRP2 FBN1

2.93e-0623594PS50026
DomainEGF-like_CS

MASP1 LRP1 LRP2 FBN1

4.44e-0626194IPR013032
DomainLdl_recept_b

LRP1 LRP2

1.87e-051492PF00058
DomainLDLRB

LRP1 LRP2

1.87e-051492PS51120
DomainLY

LRP1 LRP2

2.16e-051592SM00135
DomainLDLR_classB_rpt

LRP1 LRP2

2.16e-051592IPR000033
DomainGrowth_fac_rcpt_

LRP1 LRP2 FBN1

4.63e-0515693IPR009030
Domain-

LRP1 LRP2

1.52e-0439922.120.10.30
DomainLDLR_class-A_CS

LRP1 LRP2

1.59e-044092IPR023415
DomainLdl_recept_a

LRP1 LRP2

2.02e-044592PF00057
Domain-

LRP1 LRP2

2.11e-0446924.10.400.10
Domain6-blade_b-propeller_TolB-like

LRP1 LRP2

2.11e-044692IPR011042
DomainLDLRA_1

LRP1 LRP2

2.30e-044892PS01209
DomainLDLa

LRP1 LRP2

2.40e-044992SM00192
DomainLDLRA_2

LRP1 LRP2

2.40e-044992PS50068
DomainLDrepeatLR_classA_rpt

LRP1 LRP2

2.40e-044992IPR002172
DomainEGF_extracell

LRP2 ITGBL1

3.60e-046092IPR013111
DomainEGF_2

LRP2 ITGBL1

3.60e-046092PF07974
DomainEGF

LRP1 LRP2

1.58e-0312692PF00008
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

3.54e-044592MM15344
PathwayREACTOME_METABOLISM_OF_FAT_SOLUBLE_VITAMINS

LRP1 LRP2

4.03e-044892M27642
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

MASP1 LRP1

6.29e-046092MM14872
PathwayWP_FATTY_ACIDS_AND_LIPOPROTEINS_TRANSPORT_IN_HEPATOCYTES

LRP1 LRP2 ENDOU

1.46e-0338193M48063
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 LRP2

1.47e-039292MM14881
PathwayWP_COMPLEMENT_SYSTEM

MASP1 LRP2

1.60e-039692M39581
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

MASP1 LRP1

1.67e-039892M27152
PathwayREACTOME_VISUAL_PHOTOTRANSDUCTION

LRP1 LRP2

1.74e-0310092M27158
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

LRP1 LRP2

6.05e-0318992MM14772
PathwayREACTOME_SENSORY_PERCEPTION

LRP1 LRP2

6.11e-0319092MM15687
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

MASP1 LRP1 LRP2

6.51e-0364593MM15232
PathwayREACTOME_METABOLISM_OF_VITAMINS_AND_COFACTORS

LRP1 LRP2

6.62e-0319892M18311
PathwayREACTOME_VESICLE_MEDIATED_TRANSPORT

MASP1 LRP1 LRP2

9.01e-0372593M27507
Pubmed

Endocytic Protein Defects in the Neural Crest Cell Lineage and Its Pathway Are Associated with Congenital Heart Defects.

LRP1 LRP2

5.95e-0829234445520
Pubmed

Exome sequencing identified new mutations in a Marfan syndrome family.

LRP1 FBN1

5.95e-0829224484584
Pubmed

Identification of the low density lipoprotein receptor-related protein (LRP) as an endocytic receptor for thrombospondin-1.

LRP1 LRP2

3.57e-074927775583
Pubmed

Role of apolipoprotein E receptors in regulating the differential in vivo neurotrophic effects of apolipoprotein E.

LRP1 LRP2

3.57e-0749211421580
Pubmed

Disabled-2 is essential for endodermal cell positioning and structure formation during mouse embryogenesis.

LRP1 LRP2

3.57e-0749212413896
Pubmed

ApoER2 is endocytosed by a clathrin-mediated process involving the adaptor protein Dab2 independent of its Rafts' association.

LRP1 LRP2

5.95e-0759216101684
Pubmed

Interaction of the apolipoprotein E receptors low density lipoprotein receptor-related protein and sorLA/LR11.

LRP1 LRP2

5.95e-0759219047013
Pubmed

Interaction of coagulation factor VIII with members of the low-density lipoprotein receptor family follows common mechanism and involves consensus residues within the A2 binding site 484-509.

LRP1 LRP2

5.95e-0759218685438
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

LRP1 LRP2 FBN1

6.79e-07719333541421
Pubmed

Interaction of cytosolic adaptor proteins with neuronal apolipoprotein E receptors and the amyloid precursor protein.

LRP1 LRP2

8.92e-076929837937
Pubmed

CD91 interacts with mannan-binding lectin (MBL) through the MBL-associated serine protease-binding site.

MASP1 LRP1

8.92e-0769221054788
Pubmed

The PX-domain protein SNX17 interacts with members of the LDL receptor family and modulates endocytosis of the LDL receptor.

LRP1 LRP2

1.25e-0679212169628
Pubmed

LDL receptor-related protein as a component of the midkine receptor.

LRP1 LRP2

2.14e-0699210772929
Pubmed

LRP2 mediates folate uptake in the developing neural tube.

LRP1 LRP2

3.27e-06119224639464
Pubmed

Stage-specific association of apolipoprotein A-I and E in developing mouse retina.

LRP1 LRP2

5.41e-06149217389516
Pubmed

Normal development and fertility of knockout mice lacking the tumor suppressor gene LRP1b suggest functional compensation by LRP1.

LRP1 LRP2

5.41e-06149215082773
Pubmed

Interactions of the low density lipoprotein receptor gene family with cytosolic adaptor and scaffold proteins suggest diverse biological functions in cellular communication and signal transduction.

LRP1 LRP2

9.09e-06189210827173
Pubmed

Congenital heart defect causing mutation in Nkx2.5 displays in vivo functional deficit.

RYR2 FBN1

1.25e-05219228302382
Pubmed

MESD is essential for apical localization of megalin/LRP2 in the visceral endoderm.

LRP1 LRP2

1.25e-05219221337463
Pubmed

Congenital Diaphragmatic Hernia Overview

LRP2 FBN1

6.12e-05469220301533
Pubmed

Chromosomal organization of candidate genes involved in cholesterol gallstone formation: a murine gallstone map.

LRP1 LRP2

6.40e-05479211208732
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

LRP1 LRP2

7.84e-05529226590417
Pubmed

ACMG recommendations for reporting of incidental findings in clinical exome and genome sequencing.

RYR2 FBN1

9.43e-05579223788249
InteractionZFP41 interactions

LRP1 LRP2 FBN1

1.78e-065793int:ZFP41
InteractionMAPK8IP2 interactions

MASP1 LRP1 LRP2

1.48e-0511593int:MAPK8IP2
InteractionCUBN interactions

LRP1 LRP2

1.86e-051592int:CUBN
InteractionZDHHC15 interactions

LRP1 LRP2 FBN1

1.90e-0512593int:ZDHHC15
InteractionSCN3A interactions

LRP1 LRP2

2.12e-051692int:SCN3A
InteractionNTN5 interactions

LRP2 FBN1

4.87e-052492int:NTN5
InteractionITGB1BP1 interactions

LRP1 LRP2

9.29e-053392int:ITGB1BP1
InteractionANKS1B interactions

LRP1 LRP2

9.87e-053492int:ANKS1B
InteractionLPL interactions

LRP1 LRP2

1.05e-043592int:LPL
InteractionLDLRAP1 interactions

LRP1 LRP2

1.17e-043792int:LDLRAP1
InteractionMBL2 interactions

MASP1 LRP1

1.17e-043792int:MBL2
InteractionCCN2 interactions

LRP1 LRP2

1.37e-044092int:CCN2
InteractionAPBA2 interactions

LRP1 LRP2

1.98e-044892int:APBA2
InteractionSERPINE1 interactions

LRP1 LRP2

2.51e-045492int:SERPINE1
InteractionMAPK8IP1 interactions

LRP1 LRP2

2.89e-045892int:MAPK8IP1
InteractionANKRD36B interactions

LRP1 LRP2

3.10e-046092int:ANKRD36B
InteractionANAPC10 interactions

LRP1 LRP2

3.98e-046892int:ANAPC10
InteractionSNX17 interactions

LRP1 LRP2

5.64e-048192int:SNX17
InteractionLRP1B interactions

LRP1 LRP2

6.21e-048592int:LRP1B
InteractionMDK interactions

LRP1 LRP2

7.11e-049192int:MDK
InteractionDAB1 interactions

LRP1 LRP2

9.81e-0410792int:DAB1
InteractionNOS1AP interactions

LRP1 LRP2

1.09e-0311392int:NOS1AP
InteractionLAMA5 interactions

GGNBP2 FBN1

1.17e-0311792int:LAMA5
InteractionGIPC1 interactions

LRP1 LRP2

1.21e-0311992int:GIPC1
InteractionTHBS1 interactions

LRP1 LRP2

1.38e-0312792int:THBS1
InteractionSYNJ2BP interactions

LRP1 LRP2

1.47e-0313192int:SYNJ2BP
InteractionDAB2 interactions

LRP1 LRP2

1.67e-0314092int:DAB2
InteractionZNF408 interactions

LRP2 FBN1

1.79e-0314592int:ZNF408
InteractionC3 interactions

MASP1 LRP1

2.04e-0315592int:C3
InteractionGRIN2B interactions

LRP1 RYR2

2.45e-0317092int:GRIN2B
InteractionAPOE interactions

LRP1 LRP2

2.48e-0317192int:APOE
InteractionLRPAP1 interactions

LRP1 LRP2

2.74e-0318092int:LRPAP1
InteractionAPBB1 interactions

LRP1 LRP2

3.21e-0319592int:APBB1
CytobandEnsembl 112 genes in cytogenetic band chr12q13

LRP1 ENDOU

2.92e-0342392chr12q13
GeneFamilyLow density lipoprotein receptors

LRP1 LRP2

1.00e-051372634
GeneFamilyProteases, serine

MASP1 ENDOU

2.48e-046372738
CoexpressionZENG_GU_ICB_CONTROL_METAGENE_3_PRECICTIVE_ICB_RESPONSE

PPP1R11 MASP1 LRP1 ITGBL1

4.98e-0721194MM17081
CoexpressionAIZARANI_LIVER_C21_STELLATE_CELLS_1

MASP1 LRP1 FBN1

3.25e-0519493M39122
CoexpressionBOQUEST_STEM_CELL_UP

LRP1 FBN1 ITGBL1

7.84e-0526193M1834
CoexpressionANASTASSIOU_MULTICANCER_INVASIVENESS_SIGNATURE

FBN1 ITGBL1

2.09e-046492M2572
CoexpressionREN_ALVEOLAR_RHABDOMYOSARCOMA_DN

LRP1 FBN1 ITGBL1

2.91e-0440793M19541
CoexpressionHELLEBREKERS_SILENCED_DURING_TUMOR_ANGIOGENESIS

LRP1 FBN1

3.03e-047792M19128
CoexpressionWONG_ENDMETRIUM_CANCER_DN

MASP1 FBN1

3.10e-047892M1311
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HRGL2B

MASP1 LRP1 LRP2

3.64e-0443993M39054
CoexpressionDESCARTES_FETAL_EYE_STROMAL_CELLS

FBN1 ITGBL1

4.22e-049192M40180
CoexpressionCAHOY_ASTROGLIAL

LRP2 ITGBL1

5.10e-0410092M2807
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_500

LRP1 LRP2 FBN1 ITGBL1

1.57e-0540894gudmap_kidney_adult_RenalCapsule_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#4_top-relative-expression-ranked_200

LRP1 FBN1

1.36e-044292gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k4_200
CoexpressionAtlaskidney_adult_RenalCapsule_top-relative-expression-ranked_1000

LRP1 LRP2 FBN1 ITGBL1

1.94e-0477894gudmap_kidney_adult_RenalCapsule_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500

LRP1 FBN1

2.26e-045492gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_2500_k-means-cluster#5

MASP1 LRP1 FBN1 ITGBL1

2.31e-0481494JC_fibro_2500_K5
CoexpressionAtlasdev lower uro neuro_e14.5_PelvicGanglion_Sox10_top-relative-expression-ranked_1000

PPP1R11 MASP1 LRP1 FBN1

3.46e-0490494gudmap_dev lower uro neuro_e14.5_PelvicGanglion_Sox10_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_500

LRP1 RYR2 FBN1

3.67e-0435793gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500

MASP1 LRP1 FBN1

3.79e-0436193gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlasdev gonad_e12.5_M_InterstitLeydig_MafB_top-relative-expression-ranked_500

MASP1 LRP1 FBN1

3.89e-0436493gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_500
CoexpressionAtlaskidney_adult_RenalCapsule_k-means-cluster#2_top-relative-expression-ranked_1000

LRP1 FBN1 ITGBL1

4.05e-0436993gudmap_kidney_adult_RenalCapsule_k2_1000
CoexpressionAtlasdev lower uro neuro_e15.5_PelvicGanglion_Sox10_top-relative-expression-ranked_500

MASP1 RYR2 FBN1

4.11e-0437193gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_500

LRP1 RYR2 FBN1

4.14e-0437293gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_500
CoexpressionAtlasAravindRamakr_EmbryoidBody-LF_top-relative-expression-ranked_2500_k-means-cluster#2

MASP1 LRP2 FBN1 ITGBL1

4.20e-0495194Arv_EB-LF_2500_K2
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_500

LRP1 RYR2 FBN1

4.58e-0438593gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_500

LRP1 RYR2 FBN1

4.69e-0438893gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_500
CoexpressionAtlasProgenitor-Cell-Biology-Consortium_reference_BronchSmoothMuscl_top-relative-expression-ranked_1000

MASP1 LRP1 FBN1 ITGBL1

4.73e-0498194PCBC_ctl_BronchSmoothMuscl_1000
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_1000

MASP1 LRP1 FBN1 ITGBL1

4.90e-0499094JC_fibro_1000
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_200

LRP1 FBN1

5.21e-048292gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_200
CoexpressionAtlasStromal Cells, FRC.MLN, gp38+ CD31- CD140a+, Lymph Node, avg-5

LRP1 FBN1

5.86e-048792GSM777050_100
CoexpressionAtlasMesoderm Day 15_vs_Mesoderm Day 5-Confounder_removed-fold2.0_adjp0.05

MASP1 LRP1 LRP2 FBN1

6.11e-04104994PCBC_ratio_MESO-15_vs_MESO-5_cfr-2X-p05
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LRP1 FBN1 ITGBL1

6.63e-0443793GSM777046_500
CoexpressionAtlasStromal Cells, Fi.Sk, gp38+ CD140a+, Skin, avg-4

LRP1 FBN1

7.28e-049792GSM777046_100
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_1000_k-means-cluster#1

LRP1 FBN1 ITGBL1

7.89e-0446493JC_fibro_1000_K1
CoexpressionAtlasJC_fibro_top-relative-expression-ranked_500

MASP1 FBN1 ITGBL1

9.47e-0449493JC_fibro_500
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

LRP1 FBN1

1.15e-0312292gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

LRP1 FBN1

1.20e-0312592gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k4_1000
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_k-means-cluster#2_top-relative-expression-ranked_500

LRP1 FBN1

1.30e-0313092gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_k2_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_200

LRP1 FBN1

1.64e-0314692gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_200
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_k-means-cluster#4_top-relative-expression-ranked_500

LRP1 FBN1

1.64e-0314692gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_k4_500
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

LRP1 FBN1

1.66e-0314792gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e12.5_M_InterstitTestis_Sma_top-relative-expression-ranked_200

LRP1 FBN1

1.80e-0315392gudmap_dev gonad_e12.5_M_InterstitTestis_Sma_200
CoexpressionAtlasdev gonad_e13.5_M_InterstitTestis_Sma_k-means-cluster#1_top-relative-expression-ranked_500

LRP1 FBN1

1.87e-0315692gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_k1_500
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MASP1 RYR2 FBN1 ITGBL1

3.14e-0818194b116c68393d8836bac080f81a8fcbeb52e0403e7
ToppCellLA|World / Chamber and Cluster_Paper

LRP1 LRP2 FBN1 ITGBL1

4.07e-0819394d4bf89437216baf489ea0239136dcedf3b6714af
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 RYR2 FBN1 ITGBL1

4.24e-08195944243190ad291d56694e2155954dbaa879c9d3844
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 RYR2 FBN1 ITGBL1

4.24e-0819594df409f94f4e83be89f7a608058ee07ce3ce3a149
ToppCellCOVID-19-lung-Fibroblast|COVID-19 / Disease (COVID-19 only), tissue and cell type

LRP1 RYR2 FBN1 ITGBL1

4.51e-08198943ec01a55ade5e1627258cc3cfebb2c3207a4cb43
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-0820094311fab076f2ceb258e3970eb21e39344b894042a
ToppCellTracheal-10x5prime-Stromal-Fibroblastic-Fibro_peribronchial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

MASP1 LRP1 FBN1 ITGBL1

4.69e-08200948ab0051544ea32eb8b3f7f8ba7582deaf8bf26c0
ToppCellParenchymal-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-0820094cf433f9b43d7db07acaf70e060f8f77c974e72f3
ToppCellSkin-Fibroblasts|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.

MASP1 LRP1 FBN1 ITGBL1

4.69e-0820094f777eadf571a1a6d246da87346a9cb9d511c2e81
ToppCellBronchial-NucSeq-Stromal-Fibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-0820094cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCellParenchymal-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-082009434f52003988ce6329d8deeee1ab875fa77e01e9d
ToppCellBronchial-NucSeq-Stromal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-0820094389cc775c8419d90fb77cd794376d2160a7bf44e
ToppCellBronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-0820094e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCellTracheal-NucSeq-Stromal-Fibroblastic-Fibro_peribronchial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

LRP1 RYR2 FBN1 ITGBL1

4.69e-082009458b38f9a484ee94191091a0659ed62ebed2d4a14
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

4.23e-06168934b2d29a7843bf45922038c093ca7ec0600756adc
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

4.30e-0616993bb43abad2c049b7f4d307737347290e01b3339a3
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

4.30e-06169935f18e3f40a5b1b167903f37516ec8181e889c7c5
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Mesenchymal-stromal_cell|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

4.30e-06169938bfa2d3bb541d02f55d7c95b8fd156c8403befca
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

4.46e-06171935d31fc9b60329d4ae3c77e4ca679359d9314397d
ToppCell3'-Broncho-tracheal-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 FBN1 ITGBL1

4.53e-0617293e37c0b5b547a7345179ab258dd2141fec7064c17
ToppCellwk_08-11-Mesenchymal-Fibroblast-Airway_fibro|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

LRP1 FBN1 ITGBL1

4.61e-0617393b23b408acc29a667cce104429afef1a6cf2720a5
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-myocytic_fibroblast-Myofibroblasts-Myofibroblasts_L.2.3.2.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

MASP1 FBN1 ITGBL1

4.78e-06175931799a7be623dc3bf53ba580a7c47d2619969d708
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

4.78e-0617593795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

4.86e-06176939bc87cd5cda2372e1bce94c9dfd408eb1dfd8d0c
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-COL13A1+_matrix_FBs|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

MASP1 FBN1 ITGBL1

4.86e-0617693510f9a14dc1c151d24d079e0cc004cdf4f86336c
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)-|343B / Donor, Lineage, Cell class and subclass (all cells)

LRP1 FBN1 ITGBL1

4.86e-06176932e94bbe17c0bb65dc58b4ebc0cb829258bd7373b
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

4.86e-06176933f8274a7ab67f9f8a8923193763a5543cfe4defa
ToppCell343B-Fibroblasts-Fibroblast-A_(Fibroblast_progenitors)|343B / Donor, Lineage, Cell class and subclass (all cells)

LRP1 FBN1 ITGBL1

4.86e-0617693f33ab41d121b59d871ad7d48ca021524a027d2ef
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

LRP1 FBN1 ITGBL1

5.03e-0617893142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

5.20e-061809332c6a3886428d82fb4355d987c6d2645f333447b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

5.20e-0618093c2746092ef251e9d5910fe96461afdd0624a24c6
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 FBN1 ITGBL1

5.20e-06180939adebde5f4ca6dcb90e9113622862e14298465ac
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 FBN1 ITGBL1

5.28e-06181933462aa1c08fbaf613b6278ab2c7a5a0940bf537d
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

LRP2 RYR2 ITGBL1

5.28e-0618193c80ffa2ded5975a88e9a1a7d333196f95237bf0a
ToppCellPND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 FBN1 ITGBL1

5.28e-06181936730e249cac55ae892cc567d9211615882f3dab4
ToppCellP15-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 FBN1 ITGBL1

5.37e-0618293e9fcae9d03a6faf85b91882c5da699037bc61aeb
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.37e-0618293f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.46e-06183937e5c467fd1b156b928f1611a12ab4affb9f714b7
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.46e-061839363294d66e3ccf152ffe5d1237106764c14390b62
ToppCellP07-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

LRP1 FBN1 ITGBL1

5.55e-061849301257e5c12e38b849fd3d9496c43ded666249ba5
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

5.55e-0618493e061e85c4bb19f49f6451ddd7a9077d7378ee365
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.64e-0618593785c55d39909fac74415f24427979691e7e694e6
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.64e-061859397a1dcacbc48dc3f41c26fbb59af35c935f894d4
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.73e-0618693d998c5b00083cf2a7cd5341a98b7374b4de73c63
ToppCellfacs-Limb_Muscle-Muscle_forelimb_and_hindlimb-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.73e-0618693a7ab70b049742dfe7ee30557031bfac6412edf52
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal-fibroblast|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.73e-061869335c88cc4eb388811fcac4323b549e5897fa8dc27
ToppCelldroplet-Kidney-KIDNEY-1m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.73e-061869394d577dbb6bfacf50632e1fe8af041b35a1e6b23
ToppCell5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

RYR2 FBN1 ITGBL1

5.73e-06186935473283fb95cee556b1f6934cf72169b676b5bcc
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 FBN1 ITGBL1

5.83e-06187934e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 FBN1 ITGBL1

5.83e-0618793d36e7fc6125e7a4310499365022d38f34b757a73
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

RYR2 FBN1 ITGBL1

5.83e-0618793bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP2 FBN1 ITGBL1

5.83e-0618793827eae63fabf6892a82ce7779b5f395958d3d628
ToppCellLA-01._Fibroblast_I|World / Chamber and Cluster_Paper

LRP1 FBN1 ITGBL1

5.83e-06187934ea486991f66c29728d127171a07b81404ec0b78
ToppCellfacs-Bladder-nan-24m-Epithelial-bladder_cell|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

5.83e-06187932c145e9d11424939dd99012a8cedf5d998b966e9
ToppCellControl-Fibroblasts-Alveolar_FB|Control / group, cell type (main and fine annotations)

RYR2 FBN1 ITGBL1

5.83e-061879392d468dde81125d51daf7abd4703741abe1ab91c
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

5.92e-0618893c32d023a69b6da79687ff8fa7485e7499db57046
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

5.92e-0618893ce85a56ac27a6432421dde93a1bafa8b943244b9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

5.92e-06188931cd5a4d744bd3777246958ea5eb94388a5cbad81
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.02e-0618993544d95df910f1b276995624509a7e41b219baca0
ToppCellLPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RYR2 FBN1

6.02e-06189932a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCellControl-Fibroblasts|Control / group, cell type (main and fine annotations)

RYR2 FBN1 ITGBL1

6.11e-06190933a42a9b98d954685d38a741f44545898d0e3e9ce
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.11e-0619093efb757f11c2809e66ddb48a5c84f5433f111cb7c
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 RYR2 ITGBL1

6.11e-0619093562ee3b025c29edf07b8b344323edb49d82f1c7e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MASP1 RYR2 ITGBL1

6.11e-0619093f5fb989afabb49d64d91324570cd8c80a4b9e67d
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.21e-061919339092a0aff8097617820c59f5fea9ee2bb4f63a2
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.21e-0619193bc353a79a1d11ca52bba5e3874a80d432e1a7715
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.21e-06191931efb47743b6834b64cb0f61721ddbe875b1a66ca
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.21e-0619193107113b930d9ad171f1b2aa20df4567c94fae7d8
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RYR2 FBN1

6.21e-0619193b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 FBN1 ITGBL1

6.21e-06191932b73fcd592d16cae8ded5e45c8fbf2d9adc8caad
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

RYR2 FBN1 ITGBL1

6.21e-061919304c4d454b57e29a8d1dcdeb4678ce71bdc29b77b
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.21e-06191931b26056df078674f37a6c06f6256b30cfcec21a7
ToppCellASK454-Mesenchymal-Fibroblast|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

RYR2 FBN1 ITGBL1

6.21e-06191931726add3f392a061536b7aff72ba84303f4a0b1f
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RYR2 FBN1 ITGBL1

6.21e-06191936688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellASK454-Mesenchymal|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

RYR2 FBN1 ITGBL1

6.21e-0619193e30ae7a12439f8a79820b13f03e822c1223fd0cb
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.21e-0619193ee5f1b1c59029c46cbb1a00935c03b9317bb9da9
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast-Degenerative_Fibroblast_119|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.31e-0619293f88aba74d6e8c594c32fe2bc095b5da28b4b28e9
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 FBN1 ITGBL1

6.31e-0619293cdc652dbfabe41b324fd85c1ed933d29fb73a49f
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

RYR2 FBN1 ITGBL1

6.31e-061929399ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293840a34c1b82d218be999ab5e1bcafd6370d7a4b1
ToppCellLPS_only-Stromal_mesenchymal|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RYR2 FBN1

6.31e-0619293162d8b5858d150ecbbd1c9bf2b19c6c9cd50a158
ToppCellkidney_cells-Adult_normal_reference-Mesenchymal-Fibroblast-Degenerative_Fibroblast|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.31e-061929341a8326cd5bc19ad5041068501bab4c72399222e
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Peribronchial_fibroblasts-Peribronchial_fibroblasts_L.2.1.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LRP1 FBN1 ITGBL1

6.31e-0619293c5f8e766453f87847b740d6988c524b3d0ef3765
ToppCellPND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LRP1 FBN1 ITGBL1

6.31e-061929329bee88b45e23f16543ffc7cc361bc5da5d16a2b
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.31e-0619293bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellfacs-Lung-18m-Mesenchymal-fibroblast-adventitial_fibroblast|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 FBN1 ITGBL1

6.31e-0619293011634a24b0c61d9b463fe755502edbc5cd70b7a
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293853a930e0641ffb50cbb4cef5837c70d75c3fc39
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal-Stroma____fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293d2c03490c5e835d0f0a732803093c64b8d4b4029
ToppCellLPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RYR2 FBN1

6.31e-0619293f4fc2b0121f879bab2bee99dfb5ff2c3ca1c0e1b
ToppCellfacs-Heart-LV-3m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293671d4e1eee5aba03c43dbc98f4b51ce42b3df5d5
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 FBN1 ITGBL1

6.31e-061929332acd89617934016cd135d2cc797e8e79ae1b37f
ToppCelldroplet-Kidney-KIDNEY-30m-Mesenchymal|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-061929349281626ecad0456fdbded2378b7028d7b589686
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

LRP1 FBN1 ITGBL1

6.31e-06192937b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Lung-nan-3m-Mesenchymal-adventitial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293eeab1cef7c36ae824381952c5b2c982368c379fd
ToppCellLPS-IL1RA+antiTNF-Stromal_mesenchymal|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LRP1 RYR2 FBN1

6.31e-06192933d0cb19f037f604253d7d728689aeaa94251e92b
ToppCelldroplet-Heart-HEART_(LV+RV_ONLY)-30m-Mesenchymal-fibroblast_of_cardiac_tissue|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-06192935e6f8206ee0b10cdba79a7c4a05452cb025a5512
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.31e-06192935105e4b577408b4e1a62d0a44c23c2b830ccad88
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb-3m-Mesenchymal-mesenchymal_stem_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293beac6b3c191b11add8e39e8d04562b478ea8929e
ToppCellfacs-Lung-nan-3m-Mesenchymal-Adventitial_Fibroblast|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LRP1 FBN1 ITGBL1

6.31e-0619293a2c31390da4962bda9a936470b0b68fa1f5d47d1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

LRP1 FBN1 ITGBL1

6.31e-0619293d3c1ad4667a1e223a83ca0fcd5991a0b96f1199a
ComputationalGenes upregulated in subsets of cells of a given type within various tumors

FBN1 ITGBL1

4.39e-045072GAVISH_3CA_METAPROGRAM_FIBROBLASTS_CAF_1
Drugcoprogen

LRP1 LRP2

4.99e-06992CID006323272
Drug25-azacoprostane

LRP1 LRP2

6.24e-061092CID000162243
DrugLY 294002; Up 200; 10uM; PC3; HT_HG-U133A

MASP1 LRP1 FBN1

4.35e-05186934463_UP
DrugFlurandrenolide [1524-88-5]; Up 200; 9.2uM; MCF7; HT_HG-U133A

MASP1 LRP2 FBN1

5.00e-05195936039_UP
Drug0179445-0000 [211246-22-9]; Up 200; 1uM; MCF7; HT_HG-U133A

RYR2 FBN1 ITGBL1

5.16e-05197934758_UP
DrugIsocarboxazid [59-63-2]; Up 200; 17.2uM; MCF7; HT_HG-U133A

LRP2 FBN1 ITGBL1

5.24e-05198934706_UP
DrugSpectinomycin dihydrochloride [21736-83-4]; Up 200; 9.8uM; HL60; HT_HG-U133A

LRP1 LRP2 ITGBL1

5.39e-05200932987_UP
Drugtetrahydroaldosterone-3-glucuronide

LRP1 LRP2

5.61e-052992CID000167918
Drugmonatepil

LRP1 LRP2

5.61e-052992CID000060810
DruguPA inhibitor

LRP1 LRP2

6.85e-053292CID000001746
DrugLMWH

MASP1 LRP1 LRP2 RYR2

7.99e-0566394CID000000772
Drugchloroquine

MASP1 LRP1 LRP2

1.59e-0428893CID000002719
DrugAC1L2AC7

LRP2 RYR2

3.21e-046992CID000068733
DrugC4 m

LRP1 LRP2

4.21e-047992CID009543487
DrugOvalbumin

LRP2 FBN1

4.54e-048292ctd:D010047
DrugThalidomide

PPP1R11 LRP2 RYR2

7.07e-0447993ctd:D013792
Drugclioquinol

LRP1 LRP2

8.74e-0411492CID000002788
Drugpitavastatin

LRP1 LRP2

8.74e-0411492CID005282451
DrugSimvastatin

LRP1 RYR2 ITGBL1

1.24e-0358193ctd:D019821
Drugezetimibe

LRP1 LRP2

1.45e-0314792CID000150311
DrugMW 1

RYR2 ENDOU

1.53e-0315192CID000073965
DrugCHAPS detergent

LRP1 RYR2

1.67e-0315892CID000107670
Drug25-hydroxycholesterol

LRP1 LRP2

1.71e-0316092CID000065094
Drugprobucol

LRP1 LRP2

1.75e-0316292CID000004912
DrugMF I

LRP1 LRP2

1.77e-0316392CID000007871
Drugdimethyloxalylglycine; Up 200; 1000uM; PC3; HG-U133A

MASP1 LRP1

1.97e-0317292584_UP
DrugTetrahydrozoline hydrochloride [522-48-5]; Up 200; 16.8uM; HL60; HT_HG-U133A

LRP1 FBN1

2.04e-03175922507_UP
Drugbutenal

MASP1 LRP1

2.16e-0318092CID000020138
Drug17-AAG; Up 200; 1uM; PC3; HT_HG-U133A

RYR2 ENDOU

2.42e-03191924442_UP
DrugOxalamine citrate salt [1949-20-8]; Down 200; 9.2uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.42e-03191924969_DN
DrugProtriptyline hydrochloride [1225-55-4]; Up 200; 13.4uM; MCF7; HT_HG-U133A

RYR2 FBN1

2.42e-03191926498_UP
Drug0175029-0000 [211245-78-2]; Up 200; 10uM; PC3; HT_HG-U133A

LRP2 FBN1

2.45e-03192926875_UP
Drugindomethacin, USP; Up 200; 100uM; PC3; HG-U133A

LRP1 FBN1

2.45e-0319292452_UP
DrugCotinine (-) [486-56-6]; Down 200; 22.6uM; PC3; HT_HG-U133A

LRP1 FBN1

2.47e-03193924650_DN
DrugLabetalol hydrochloride [32780-64-6]; Up 200; 11uM; MCF7; HT_HG-U133A

RYR2 FBN1

2.47e-03193926809_UP
DrugMinocycline hydrochloride [13614-98-7]; Up 200; 8uM; PC3; HT_HG-U133A

MASP1 RYR2

2.50e-03194925077_UP
DrugTrichlormethiazide [133-67-5]; Up 200; 10.6uM; HL60; HT_HG-U133A

LRP2 FBN1

2.50e-03194922998_UP
DrugMetaproterenol sulfate, orciprenaline sulfate [5874-97-5]; Down 200; 7.6uM; HL60; HT_HG-U133A

LRP2 FBN1

2.50e-03194922485_DN
DrugCinchonine [118-10-5]; Up 200; 13.6uM; MCF7; HT_HG-U133A

LRP2 FBN1

2.50e-03194922789_UP
DrugIopanoic acid [96-83-3]; Down 200; 7uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.50e-03194925448_DN
DrugCarbamazepine [298-46-4]; Up 200; 17uM; PC3; HT_HG-U133A

FBN1 ITGBL1

2.50e-03194921805_UP
DrugPhenelzine sulfate [156-51-4]; Up 200; 17uM; PC3; HT_HG-U133A

LRP1 LRP2

2.50e-03194924538_UP
DrugFluspirilen [1841-19-6]; Down 200; 8.4uM; PC3; HT_HG-U133A

RYR2 FBN1

2.53e-03195926662_DN
DrugAmethopterin (R,S) [59-05-2]; Down 200; 8.8uM; PC3; HT_HG-U133A

RYR2 FBN1

2.53e-03195926654_DN
DrugGlipizide [29094-61-9]; Up 200; 9uM; MCF7; HT_HG-U133A

RYR2 FBN1

2.53e-03195924991_UP
DrugFlunisolide [3385-03-3]; Down 200; 9.2uM; HL60; HT_HG-U133A

LRP2 FBN1

2.53e-03195922168_DN
DrugEthamsylate [2624-44-4]; Down 200; 15.2uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.53e-03195924399_DN
Drug17-DMAG; Up 200; 0.1uM; HL60; HT_HG-U133A

MASP1 LRP1

2.53e-03195926172_UP
DrugTestosterone propionate [57-85-2]; Down 200; 11.6uM; PC3; HT_HG-U133A

LRP1 RYR2

2.53e-03195924676_DN
DrugCarbimazole [22232-54-8]; Down 200; 21.4uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.53e-03195925399_DN
Drug6-Hydroxytropinone [5932-53-6]; Down 200; 25.8uM; PC3; HT_HG-U133A

LRP1 RYR2

2.53e-03195924250_DN
DrugPrazosin hydrochloride [19237-84-4]; Down 200; 9.6uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.53e-03195925416_DN
DrugSulfapyridine [144-83-2]; Up 200; 16uM; HL60; HT_HG-U133A

RYR2 FBN1

2.53e-03195922538_UP
Drugsodium 4-phenylbutyrate; Down 200; 1000uM; PC3; HG-U133A

FBN1 ITGBL1

2.53e-0319592434_DN
DrugTriamcinolone [124-94-7]; Down 200; 10.2uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.53e-03195922241_DN
DrugAcetaminophen [103-90-2]; Up 200; 26.4uM; HL60; HT_HG-U133A

LRP1 ITGBL1

2.55e-03196923025_UP
DrugGuanethidine sulfate [60-02-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

MASP1 RYR2

2.55e-03196923171_UP
DrugDehydroisoandosterone 3-acetate [853-23-6]; Down 200; 12.2uM; PC3; HT_HG-U133A

LRP1 RYR2

2.55e-03196926673_DN
DrugPrednisolone [50-24-8]; Down 200; 11uM; HL60; HT_HG-U133A

LRP2 FBN1

2.55e-03196922393_DN
DrugPramoxine hydrochloride [637-58-1]; Down 200; 12.2uM; HL60; HT_HG-U133A

RYR2 FBN1

2.55e-03196922198_DN
Drug3-alpha-Hydroxy-5-beta-androstan-17-one [53-42-9]; Down 200; 13.8uM; PC3; HT_HG-U133A

RYR2 FBN1

2.55e-03196923742_DN
DrugResveratrol [501-36-0]; Up 200; 17.6uM; PC3; HT_HG-U133A

LRP1 LRP2

2.55e-03196925084_UP
DrugIoxaglic acid [59017-64-0]; Up 200; 3.2uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.55e-03196927470_UP
DrugAlfuzosin hydrochloride [81403-68-1]; Up 200; 9.4uM; PC3; HT_HG-U133A

LRP2 RYR2

2.55e-03196924644_UP
DrugSulfadiazine [68-35-9]; Down 200; 16uM; MCF7; HT_HG-U133A

LRP2 RYR2

2.55e-03196925523_DN
Diseaseaortic measurement

MASP1 LRP1 RYR2 FBN1

3.48e-0725184EFO_0020865
Diseasedescending aortic diameter

MASP1 LRP1 FBN1

1.42e-068883EFO_0021788
Diseaseaortic aneurysm

LRP1 FBN1

2.89e-061082EFO_0001666
Diseaseascending aortic diameter

MASP1 RYR2 FBN1

5.75e-0614083EFO_0021787
Diseasespontaneous coronary artery dissection

LRP1 FBN1

2.98e-053182EFO_0010820
Diseaseheart disease (implicated_via_orthology)

RYR2 FBN1

4.50e-053882DOID:114 (implicated_via_orthology)
Diseasediastolic blood pressure, systolic blood pressure

LRP1 RYR2 FBN1

5.99e-0467083EFO_0006335, EFO_0006336
DiseaseCraniofacial Abnormalities

MASP1 LRP2

7.62e-0415682C0376634
Diseaseattempted suicide

LRP2 FBN1

9.89e-0417882EFO_0004321

Protein segments in the cluster

PeptideGeneStartEntry
EHGDDSCVHHCEDKE

GGNBP2

496

Q9H3C7
SCVHHCEDKEDDGDS

GGNBP2

501

Q9H3C7
DKEDDCEHGEDETHC

LRP1

2716

Q07954
CEDYEHLCTEDHKES

ENDOU

51

P21128
VDDCGDGTDETEEHC

LRP2

3906

P98164
ESDEEEEEGCGHTHC

PPP1R11

76

O60927
KDEDECEEGKHDCTE

FBN1

2246

P35555
DECKEREDEELSCDH

MASP1

141

P48740
AKSCHDEEDDDGEEE

RYR2

3696

Q92736
EFCDCDDRDCDKHDG

ITGBL1

446

O95965