Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	nuclear body	BLM HIVEP1 SRSF4 UBN1 SRSF8 EPC1 CHEK2 FAM76B PLAG1 PLEKHH2 RGS10 TP53BP1	1.91e-05	903	65	12	GO:0016604
GeneOntologyCellularComponent	axon initial segment	NAV1 LRRC7 ADAM22	9.90e-05	29	65	3	GO:0043194
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ABCA2 ANKS6 UBN1 MYCBP2 PIK3C2B FOSL2 DUSP16 NAV2 NAV1 LRP5 CHD8 IRS1 SRGAP2 WNK1 WNK2 IQCE	1.86e-10	1105	66	16	35748872
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	BLM WWC2 HIVEP1 UBN1 MYCBP2 UBAP2L FOSL2 TRAPPC10 FAM76B MED1 ARHGEF6 TP53BP1	2.22e-08	774	66	12	15302935
Pubmed	A human MAP kinase interactome.	HIVEP1 KIAA0232 DUSP16 NAV2 NAV1 CHD8 NKTR WNK1 OBI1 WNK2	2.71e-08	486	66	10	20936779
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	BLM UBAP2L EPC1 NAV2 CHD8 MED1 WNK1 OBI1 ARHGEF6 TP53BP1	3.74e-08	503	66	10	16964243
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	BLM FLG ANKS6 MYCBP2 NAV1 TRAPPC10 SRGAP2 NKTR MED1 WNK1 CLOCK PCDH9 ARHGEF6 TP53BP1	1.48e-07	1321	66	14	27173435
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	WWC2 HIVEP1 MYCBP2 PIK3C2B KIAA0232 NAV2 NAV1 IRS1 SRGAP2 WNK1 OBI1	6.24e-07	861	66	11	36931259
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	BLM HIVEP1 SRSF4 UBN1 LMNB1 UBAP2L U2SURP FAM76B CHD8 MED1 TP53BP1	1.69e-06	954	66	11	36373674
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	DMXL2 LMNB1 MYCBP2 UBAP2L NAV1 CHD8 LRRC7 SRGAP2 ADAM22 WNK2 TP53BP1	1.85e-06	963	66	11	28671696
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SRSF4 TENT4A MYCBP2 UBAP2L NAV1 WNK1 ADAM22 WNK2	2.67e-06	462	66	8	31138677
Pubmed	WNK Inhibition Increases Surface Liquid pH and Host Defense in Cystic Fibrosis Airway Epithelia.	WNK1 WNK2	3.55e-06	2	66	2	35849656
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	MYCBP2 UBAP2L KIAA0232 FOSL2 TTLL11 TTC14 NAV1 SLC9A7 LRP5 LRRC7 SRGAP2 GREB1 WNK2	3.79e-06	1489	66	13	28611215
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	DMXL2 MYCBP2 KIAA0232 NAV2 CHD8 WNK1	4.51e-06	225	66	6	12168954
Pubmed	Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs.	ABCA2 COL17A1 UBAP2L U2SURP NAV1	5.03e-06	130	66	5	12421765
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	BLM SRSF4 UBN1 LMNB1 SRSF8 FOSL2 U2SURP EPC1 NKTR MED1 CLOCK MXI1	5.13e-06	1294	66	12	30804502
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	WWC2 UBAP2L TTC14 TRAPPC10 FAM76B CRYBG1 TMEM39B SRGAP2 WNK1 ARHGEF6 TP53BP1	5.74e-06	1084	66	11	11544199
Pubmed	The protein interaction landscape of the human CMGC kinase group.	SRSF4 UBAP2L SRSF8 KIAA0232 CHEK2 NAV1 FAM76B MED1 OBI1	6.47e-06	695	66	9	23602568
Pubmed	DNA repair and cell cycle checkpoint defects in a mouse model of 'BRCAness' are partially rescued by 53BP1 deletion.	BLM TP53BP1	1.06e-05	3	66	2	29620483
Pubmed	Neuron navigator: a human gene family with homology to unc-53, a cell guidance gene from Caenorhabditis elegans.	NAV2 NAV1	1.06e-05	3	66	2	12079279
Pubmed	Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53.	NAV2 NAV1	1.06e-05	3	66	2	15158073
Pubmed	Wnk kinases are positive regulators of canonical Wnt/β-catenin signalling.	WNK1 WNK2	1.06e-05	3	66	2	23797875
Pubmed	Pore membrane and/or filament interacting like protein 1 (POMFIL1) is predominantly expressed in the nervous system and encodes different protein isoforms.	NAV2 NAV1	1.06e-05	3	66	2	12062803
Pubmed	WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway.	TRPV5 WNK2	1.06e-05	3	66	2	18768590
Pubmed	BLM helicase-dependent and -independent roles of 53BP1 during replication stress-mediated homologous recombination.	BLM TP53BP1	1.06e-05	3	66	2	17591918
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	HIVEP1 FOSL2 U2SURP EPC1 CHD8 MED1	1.22e-05	268	66	6	33640491
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	BLM HIVEP1 UBN1 PIK3C2B NAV1 WNK1 OBI1 TP53BP1	1.54e-05	588	66	8	38580884
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	BLM MYCBP2 UBAP2L CHD8 NKTR MED1 TP53BP1	2.02e-05	440	66	7	34244565
Pubmed	Differential expression of paralog RNA binding proteins establishes a dynamic splicing program required for normal cerebral cortex development.	CHD8 LRRC7 WNK1	2.07e-05	28	66	3	38324473
Pubmed	BLM helicase regulates DNA repair by counteracting RAD51 loading at DNA double-strand break sites.	BLM TP53BP1	2.12e-05	4	66	2	28912125
Pubmed	A positive feedback loop links circadian clock factor CLOCK-BMAL1 to the basic transcriptional machinery.	MED1 CLOCK	2.12e-05	4	66	2	24043798
Pubmed	Axon morphogenesis and maintenance require an evolutionary conserved safeguard function of Wnk kinases antagonizing Sarm and Axed.	WNK1 WNK2	2.12e-05	4	66	2	34384519
Pubmed	Phosphorylation-dependent interactions of BLM and 53BP1 are required for their anti-recombinogenic roles during homologous recombination.	BLM TP53BP1	2.12e-05	4	66	2	17984114
Pubmed	WNK kinases, a novel protein kinase subfamily in multi-cellular organisms.	WNK1 WNK2	2.12e-05	4	66	2	11571656
Pubmed	Human hypertension caused by mutations in WNK kinases.	WNK1 WNK2	2.12e-05	4	66	2	11498583
Pubmed	Structural Basis for EPC1-Mediated Recruitment of MBTD1 into the NuA4/TIP60 Acetyltransferase Complex.	EPC1 TP53BP1	2.12e-05	4	66	2	32209463
Pubmed	Endogenous gamma-H2AX-ATM-Chk2 checkpoint activation in Bloom's syndrome helicase deficient cells is related to DNA replication arrested forks.	BLM CHEK2	2.12e-05	4	66	2	17634426
Pubmed	ATR and ATM-dependent movement of BLM helicase during replication stress ensures optimal ATM activation and 53BP1 focus formation.	BLM TP53BP1	2.12e-05	4	66	2	15539948
Pubmed	NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage.	CHEK2 TP53BP1	2.12e-05	4	66	2	12551934
Pubmed	53BP1 loss induces chemoresistance of colorectal cancer cells to 5-fluorouracil by inhibiting the ATM-CHK2-P53 pathway.	CHEK2 TP53BP1	2.12e-05	4	66	2	27838786
Pubmed	STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.	KIAA0232 FOSL2 OBI1	2.82e-05	31	66	3	28089446
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	UBN1 MYCBP2 UBAP2L EPC1 NAV1 MED1 WNK1 ARHGEF6	2.99e-05	645	66	8	25281560
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	WWC2 LMNB1 MYCBP2 PIK3C2B SRGAP2	3.15e-05	190	66	5	15161933
Pubmed	Checkpoint-dependent phosphorylation of Med1/TRAP220 in response to DNA damage.	CHEK2 MED1	3.53e-05	5	66	2	28430840
Pubmed	A mitotic phosphorylation feedback network connects Cdk1, Plk1, 53BP1, and Chk2 to inactivate the G(2)/M DNA damage checkpoint.	CHEK2 TP53BP1	3.53e-05	5	66	2	20126263
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	BLM FLG DMXL2 SRSF4 LMNB1 MYCBP2 U2SURP FAM76B MED1 ARHGEF6	3.54e-05	1082	66	10	38697112
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	SRSF4 UBN1 FOSL2 NAV1 PLAG1 CHD8	4.06e-05	332	66	6	37433992
Pubmed	Unproductive splicing of SR genes associated with highly conserved and ultraconserved DNA elements.	SRSF4 SRSF8	5.29e-05	6	66	2	17361132
Pubmed	Expression of Muc19/Smgc gene products during murine sublingual gland development: cytodifferentiation and maturation of salivary mucous cells.	MUC16 MUC6	5.29e-05	6	66	2	19110483
Pubmed	A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency.	CHEK2 TP53BP1	5.29e-05	6	66	2	19716796
Pubmed	BRCA1 safeguards genome integrity by activating chromosome asynapsis checkpoint to eliminate recombination-defective oocytes.	CHEK2 TP53BP1	5.29e-05	6	66	2	38696471
Pubmed	WNK2 kinase is a novel regulator of essential neuronal cation-chloride cotransporters.	WNK1 WNK2	5.29e-05	6	66	2	21733846
Pubmed	Serum and glucocorticoid-induced kinase (SGK) 1 and the epithelial sodium channel are regulated by multiple with no lysine (WNK) family members.	WNK1 WNK2	7.40e-05	7	66	2	20525693
Pubmed	TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.	BLM TP53BP1	7.40e-05	7	66	2	25344324
Pubmed	Dynamic microtubules catalyze formation of navigator-TRIO complexes to regulate neurite extension.	NAV2 NAV1	7.40e-05	7	66	2	25065758
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	COL17A1 U2SURP WNK1 WNK2 TP53BP1	8.62e-05	235	66	5	30258100
Pubmed	DNA damage response in microcephaly development of MCPH1 mouse model.	CHEK2 TP53BP1	9.86e-05	8	66	2	23683352
Pubmed	KLHL2 interacts with and ubiquitinates WNK kinases.	WNK1 WNK2	9.86e-05	8	66	2	23838290
Pubmed	53BP1 promotes ATM activity through direct interactions with the MRN complex.	CHEK2 TP53BP1	9.86e-05	8	66	2	20010693
Pubmed	The CUL3-KLHL3 E3 ligase complex mutated in Gordon's hypertension syndrome interacts with and ubiquitylates WNK isoforms: disease-causing mutations in KLHL3 and WNK4 disrupt interaction.	WNK1 WNK2	9.86e-05	8	66	2	23387299
Pubmed	Mechanism of DNA resection during intrachromosomal recombination and immunoglobulin class switching.	BLM TP53BP1	9.86e-05	8	66	2	23254285
Pubmed	DYNLL1 binds to MRE11 to limit DNA end resection in BRCA1-deficient cells.	BLM TP53BP1	9.86e-05	8	66	2	30464262
Pubmed	BioID identifies novel c-MYC interacting partners in cultured cells and xenograft tumors.	U2SURP EPC1 CHD8 MED1	1.26e-04	134	66	4	25452129
Pubmed	Proteomic, functional, and domain-based analysis of in vivo 14-3-3 binding proteins involved in cytoskeletal regulation and cellular organization.	MYCBP2 IRS1 SRGAP2 WNK1 ARHGEF6	1.26e-04	255	66	5	15324660
Pubmed	Functional and comparative genomic analysis of the piebald deletion region of mouse chromosome 14.	MYCBP2 OBI1	1.58e-04	10	66	2	12160731
Pubmed	Insights into the ubiquitin-proteasome system of human embryonic stem cells.	SRSF4 LMNB1 U2SURP SRGAP2 MED1	1.62e-04	269	66	5	29511261
Pubmed	Unbiased Identification of trans Regulators of ADAR and A-to-I RNA Editing.	BLM U2SURP CHD8 MED1 TP53BP1	1.68e-04	271	66	5	32433965
Pubmed	The ISWI ATPase Smarca5 (Snf2h) Is Required for Proliferation and Differentiation of Hematopoietic Stem and Progenitor Cells.	CHEK2 TP53BP1	1.93e-04	11	66	2	28276606
Pubmed	Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest.	BLM TP53BP1	1.93e-04	11	66	2	15364958
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	BLM PHKA2 FOSL2 EPC1 CHEK2 OBI1 TP53BP1 MXI1	2.14e-04	857	66	8	25609649
Pubmed	Telomere shortening triggers senescence of human cells through a pathway involving ATM, p53, and p21(CIP1), but not p16(INK4a).	CHEK2 TP53BP1	2.31e-04	12	66	2	15149599
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	BLM SRSF4 MYCBP2 UBAP2L U2SURP CHD8 TP53BP1	2.38e-04	653	66	7	22586326
Pubmed	A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.	HIVEP1 LMNB1 MYCBP2 TMEM39B	2.61e-04	162	66	4	21890473
Pubmed	S6K1 phosphorylation-dependent degradation of Mxi1 by β-Trcp ubiquitin ligase promotes Myc activation and radioresistance in lung cancer.	CHEK2 MXI1	2.73e-04	13	66	2	29507620
Pubmed	A rational nomenclature for serine/arginine-rich protein splicing factors (SR proteins).	SRSF4 SRSF8	2.73e-04	13	66	2	20516191
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	DMXL2 MYCBP2 UBAP2L U2SURP NAV1 LRRC7 ADAM22 WNK2 TP53BP1	2.91e-04	1139	66	9	36417873
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	FLG DMXL2 UBN1 TTC14 SRGAP2 NKTR PLEKHH2	3.29e-04	689	66	7	36543142
Pubmed	Targeting SKA3 suppresses the proliferation and chemoresistance of laryngeal squamous cell carcinoma via impairing PLK1-AKT axis-mediated glycolysis.	UBAP2L U2SURP TP53BP1	3.54e-04	72	66	3	33106477
Pubmed	SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis.	CHEK2 TP53BP1	4.18e-04	16	66	2	33200984
Pubmed	Docking motif-guided mapping of the interactome of protein phosphatase-1.	UBN1 TRIM42 WNK1	4.83e-04	80	66	3	19389623
Pubmed	Quantitative phosphoproteome analysis using a dendrimer conjugation chemistry and tandem mass spectrometry.	UBAP2L ARHGEF6 TP53BP1	4.83e-04	80	66	3	16094384
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ABCA2 NAV2 CHD8 CLOCK WNK2 IQCE	5.05e-04	529	66	6	14621295
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	DMXL2 MYCBP2 UBAP2L LRRC7 ADAM22	5.21e-04	347	66	5	17114649
Pubmed	Mucin gene expression in human laryngeal epithelia: effect of laryngopharyngeal reflux.	MUC16 MUC6	5.32e-04	18	66	2	18834073
Pubmed	PTIP associates with MLL3- and MLL4-containing histone H3 lysine 4 methyltransferase complex.	BLM TP53BP1	5.32e-04	18	66	2	17500065
Pubmed	The nuclear import of the small GTPase Rac1 is mediated by the direct interaction with karyopherin alpha2.	LMNB1 ARHGEF6	5.32e-04	18	66	2	19961560
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ABCA2 ADAMTSL1 WNK1	5.57e-04	84	66	3	15203218
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	PHKA2 MYCBP2 TP53BP1	5.77e-04	85	66	3	16051665
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	LMNB1 MYCBP2 UBAP2L CHD8 MED1 TP53BP1	6.14e-04	549	66	6	38280479
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	HIVEP1 LMNB1 MYCBP2 CHEK2 OBI1	6.23e-04	361	66	5	26167880
Pubmed	High-throughput analyses of hnRNP H1 dissects its multi-functional aspect.	WWC2 SRSF4 LMNB1 PIK3C2B UBAP2L FOSL2 MED1 WNK1	6.84e-04	1021	66	8	26760575
Pubmed	Nde1 is required for heterochromatin compaction and stability in neocortical neurons.	LMNB1 TP53BP1	7.28e-04	21	66	2	35601919
Pubmed	LncRNA H19 Regulates Breast Cancer DNA Damage Response and Sensitivity to PARP Inhibitors via Binding to ILF2.	SRSF8 U2SURP	7.99e-04	22	66	2	37298108
Pubmed	Chromosomal mapping of five highly conserved murine homologues of the Drosophila RING finger gene seven-in-absentia.	COL17A1 MXI1	8.75e-04	23	66	2	9143490
Pubmed	Functional genetic analysis of mouse chromosome 11.	MED1 FREM1	8.75e-04	23	66	2	12955145
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	BLM U2SURP CHD8 MED1 TP53BP1	9.22e-04	394	66	5	27248496
Pubmed	Exploring the link between MORF4L1 and risk of breast cancer.	BLM CHEK2	9.53e-04	24	66	2	21466675
Pubmed	Murine chromosomal location of five bHLH-Zip transcription factor genes.	COL17A1 MXI1	9.53e-04	24	66	2	8530024
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	MYCBP2 PIK3C2B IRS1	9.80e-04	102	66	3	15778465
Pubmed	Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.	HIVEP1 UBAP2L WNK2 IQCE	1.02e-03	233	66	4	37704626
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	U2SURP WNK1 CLOCK	1.04e-03	104	66	3	9205841
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	HIVEP1 MYCBP2 FOSL2 U2SURP FAM76B CHD8 MED1 TP53BP1	1.12e-03	1103	66	8	34189442
Interaction	YWHAH interactions	WWC2 ABCA2 HIVEP1 MYCBP2 PIK3C2B SRSF8 KIAA0232 DUSP16 NAV2 NAV1 TRAPPC10 IRS1 SRGAP2 NKTR MED1 WNK1 ARHGEF6 WNK2	9.36e-09	1102	66	18	int:YWHAH
Interaction	TOP3B interactions	ABCA2 ANKS6 UBN1 MYCBP2 PIK3C2B UBAP2L FOSL2 DUSP16 NAV2 NAV1 LRP5 CHD8 IRS1 SRGAP2 WNK1 WNK2 TP53BP1 IQCE	7.22e-07	1470	66	18	int:TOP3B
Interaction	YWHAZ interactions	WWC2 DMXL2 HIVEP1 MYCBP2 PIK3C2B SRSF8 KIAA0232 DUSP16 NAV2 NAV1 IRS1 SRGAP2 WNK1 ADAM22 ARHGEF6 WNK2 TP53BP1	7.83e-07	1319	66	17	int:YWHAZ
Interaction	SFN interactions	WWC2 SRSF4 MYCBP2 PIK3C2B SRSF8 KIAA0232 NAV2 NAV1 IRS1 SRGAP2 WNK1 OBI1	2.20e-06	692	66	12	int:SFN
Interaction	YWHAB interactions	WWC2 HIVEP1 LMNB1 MYCBP2 PIK3C2B KIAA0232 DUSP16 NAV2 NAV1 TRAPPC10 IRS1 SRGAP2 WNK1 ADAM22	4.07e-06	1014	66	14	int:YWHAB
Interaction	YWHAG interactions	WWC2 HIVEP1 MYCBP2 PIK3C2B SRSF8 KIAA0232 DUSP16 NAV2 NAV1 TRAPPC10 IRS1 SRGAP2 NKTR WNK1 ARHGEF6	9.34e-06	1248	66	15	int:YWHAG
Interaction	HERC2 interactions	BLM PHKA2 SRSF4 LMNB1 MYCBP2 U2SURP SRGAP2 MED1 TP53BP1	3.66e-05	503	66	9	int:HERC2
Interaction	YWHAE interactions	WWC2 HIVEP1 SRSF4 LMNB1 MYCBP2 PIK3C2B KIAA0232 DUSP16 NAV2 NAV1 IRS1 SRGAP2 WNK1 WNK2	4.52e-05	1256	66	14	int:YWHAE
Interaction	PER3 interactions	FAT3 CHEK2 CLOCK	6.46e-05	24	66	3	int:PER3
Interaction	SRPK2 interactions	HIVEP1 SRSF4 LMNB1 MYCBP2 SRSF8 U2SURP CHEK2 FAM76B NKTR OBI1	1.06e-04	717	66	10	int:SRPK2
GeneFamily	RNA binding motif containing\|Serine and arginine rich splicing factors	SRSF4 SRSF8	4.67e-04	12	49	2	737
GeneFamily	CD molecules\|Mucins	MUC16 MUC6	1.46e-03	21	49	2	648
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	GAB3 IRS1 PLEKHH2 ARHGEF6	2.32e-03	206	49	4	682
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	BLM DMXL2 HIVEP1 LMNB1 MYCBP2 U2SURP IRS1 SRGAP2 MED1 CLOCK TP53BP1	8.81e-06	856	66	11	M4500
Coexpression	GSE35685_CD34POS_CD38NEG_VS_CD34POS_CD10NEG_CD62LPOS_BONE_MARROW_UP	MYCBP2 DUSP16 NAV2 CRYBG1 WNK1 RGS10	1.14e-05	200	66	6	M9083
Coexpression	RAMASWAMY_METASTASIS_UP	UBN1 LMNB1 TENT4A SRGAP2	2.35e-05	66	66	4	M6698
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000	FAT3 MUC16 PLAG1 IRS1 PLEKHH2 WNK1 PCDH9 FREM1	1.45e-06	265	65	8	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#1_top-relative-expression-ranked_1000	LMNB1 FAT3 MUC16 PLAG1 IRS1 PLEKHH2 PCDH9 FREM1	4.62e-06	310	65	8	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k1_1000
CoexpressionAtlas	FacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#3	PHKA2 ABCA2 FAT3 DUSP16 TRAPPC10 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	1.21e-05	730	65	11	Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K3
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#2	PHKA2 ABCA2 FAT3 DUSP16 TRAPPC10 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	1.50e-05	747	65	11	Facebase_RNAseq_ratio_e10.5_MaxillaryArch_vs_Mandibular_2500_K2
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#4	ABCA2 FAT3 DUSP16 TRAPPC10 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	6.34e-05	721	65	10	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K4
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#5	ABCA2 FAT3 DUSP16 TRAPPC10 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	6.41e-05	722	65	10	Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K5
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_k-means-cluster#3_top-relative-expression-ranked_1000	LMNB1 FAT3 MUC16 PLAG1 IRS1 PCDH9 FREM1	7.39e-05	336	65	7	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_k3_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000	FAT3 NAV2 SLC9A7 MUC16 PLAG1 IRS1 PLEKHH2 WNK1 PCDH9 FREM1	7.86e-05	740	65	10	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_1000_k-means-cluster#1	ABCA2 FAT3 PCDH9 ADAM22 ARHGEF6 WNK2	7.87e-05	233	65	6	Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_1000_K1
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#5	ABCA2 FAT3 DUSP16 TRAPPC10 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	8.13e-05	743	65	10	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K5
CoexpressionAtlas	dev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000	LMNB1 FAT3 MUC16 PLAG1 IRS1 PLEKHH2 FREM1	1.02e-04	354	65	7	gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_1000_k-means-cluster#2	ABCA2 FAT3 PCDH9 ADAM22 ARHGEF6 WNK2	1.13e-04	249	65	6	Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_1000_K2
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_500	FAT3 MUC16 PLAG1 IRS1 PLEKHH2 PCDH9 FREM1	1.16e-04	361	65	7	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitTestis_Sma_top-relative-expression-ranked_1000	ADAMTSL1 LMNB1 FAT3 NAV1 MUC16 PLAG1 IRS1 PLEKHH2 PCDH9 FREM1	1.18e-04	777	65	10	gudmap_dev gonad_e13.5_M_InterstitTestis_Sma_1000
CoexpressionAtlas	dev gonad_e12.5_M_InterstitLeydig_MafB_k-means-cluster#2_top-relative-expression-ranked_500	FAT3 MUC16 IRS1 PCDH9 FREM1	1.51e-04	165	65	5	gudmap_dev gonad_e12.5_M_InterstitLeydig_MafB_k2_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000	LMNB1 MYCBP2 FAT3 TTC14 PLAG1 MED1 WNK1	1.72e-04	385	65	7	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlas	FacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#5	ABCA2 FAT3 DUSP16 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	2.36e-04	688	65	9	Facebase_RNAseq_e10.5_Mandibular Arch_2500_K5
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#4_top-relative-expression-ranked_500	FAT3 MUC16 IRS1 PLEKHH2 FREM1	4.31e-04	207	65	5	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k4_500
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#2	ABCA2 FAT3 DUSP16 CHD8 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	4.31e-04	747	65	9	Facebase_RNAseq_e9.5_Maxillary Arch_2500_K2
CoexpressionAtlas	dev gonad_e11.5_F_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000	FOSL2 MUC16 PLAG1 IRS1 PLEKHH2 FREM1	4.90e-04	327	65	6	gudmap_dev gonad_e11.5_F_GonMes_Sma_k4_1000
CoexpressionAtlas	dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500	MUC16 PLAG1 PCDH9 FREM1	5.36e-04	122	65	4	gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_1000	LMNB1 FAT3 NAV1 MUC16 PLAG1 IRS1 PLEKHH2 PCDH9 FREM1	5.52e-04	773	65	9	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_1000
CoexpressionAtlas	dev gonad_e11.5_M_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000	LMNB1 FAT3 MUC16 IRS1 PLEKHH2 FREM1	5.74e-04	337	65	6	gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_k1_1000
CoexpressionAtlas	FacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_1000_k-means-cluster#4	FAT3 PCDH9 ADAM22 ARHGEF6 WNK2	6.05e-04	223	65	5	Facebase_RNAseq_e9.5_Facial Mesenchyne_1000_K4
CoexpressionAtlas	dev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000	HIVEP1 FAT3 NAV2 MUC16 PLAG1 IRS1 PLEKHH2 FREM1 MXI1	6.05e-04	783	65	9	gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlas	dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k-means-cluster#2_top-relative-expression-ranked_500	FAT3 PCDH9 FREM1	6.07e-04	54	65	3	gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_k2_500
CoexpressionAtlas	dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k-means-cluster#2_top-relative-expression-ranked_500	ADAMTSL1 FAT3 LRRC7 FREM1	6.23e-04	127	65	4	gudmap_dev lower uro neuro_e15.5_PelvicGanglion_Sox10_k2_500
CoexpressionAtlas	FacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_1000_k-means-cluster#4	FAT3 PCDH9 ADAM22 ARHGEF6 WNK2	7.23e-04	232	65	5	Facebase_RNAseq_e9.5_Maxillary Arch_1000_K4
CoexpressionAtlas	dev gonad_e13.5_M_InterstitFLeydig_MafB_top-relative-expression-ranked_500	FAT3 MUC16 PLAG1 IRS1 PCDH9 FREM1	7.65e-04	356	65	6	gudmap_dev gonad_e13.5_M_InterstitFLeydig_MafB_500
CoexpressionAtlas	kidney_e13.5_Podocyte_MafB_k-means-cluster#1_top-relative-expression-ranked_100	FAT3 FREM1	8.20e-04	14	65	2	gudmap_kidney_e13.5_Podocyte_MafB_k1_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	ADAMTSL1 COL17A1 LMNB1 MYCBP2 FAT3 TTC14 PLAG1 MED1 WNK1	8.26e-04	818	65	9	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	FacebaseRNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#5	ABCA2 FAT3 DUSP16 PCDH9 ADAM22 ARHGEF6 WNK2 MXI1	8.67e-04	658	65	8	Facebase_RNAseq_ratio_e10.5_MandibularArch_vs_MaxillaryArch_2500_K5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FOSL2 CRYBG1 WNK1 TRPV5 ADAM22 FREM1	3.40e-07	186	66	6	b3358e0fa6d845c81e94d56c8575f016621d28ff
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 PCDH9 TRPV5 ADAM22 FREM1	3.63e-07	188	66	6	4154f4787483c7e076e87a187733a9f666742c3d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22 FREM1	4.52e-06	164	66	5	6fb2136168f430babfeb81ca7e151ca7a8092ec4
ToppCell	Dendritic_Cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	LDLRAD2 LMNB1 NAV1 SLC9A7 ARHGEF6	6.55e-06	177	66	5	d2cd081bdda0eba9f6f6473c4d3939e4bee3440e
ToppCell	Control-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 LRRC7 PLEKHH2 ADAM22 FREM1	7.11e-06	180	66	5	08ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22 FREM1	7.11e-06	180	66	5	788d5fbf688365b5d92d3aa19b9f8e9448f8be5a
ToppCell	Control-APC-like-Dendritic_cells\|Control / group, cell type (main and fine annotations)	NAV1 SLC9A7 CRYBG1 SRGAP2 RGS10	7.70e-06	183	66	5	8f9c8e2436f18ea7c265b08e4e149e19cb513a16
ToppCell	Control-APC-like\|Control / group, cell type (main and fine annotations)	NAV1 SLC9A7 CRYBG1 SRGAP2 RGS10	7.70e-06	183	66	5	c313ac72cc9fa1583456d452393f61f0a4ca33a8
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	MYCBP2 GREB1 PCDH9 ADAM22 FREM1	7.91e-06	184	66	5	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22 FREM1	8.34e-06	186	66	5	d65fa6d8e8a195ea10cfde1499d096d6acf7a634
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22 FREM1	8.34e-06	186	66	5	08632045d499e61dd96ff29a5a9a208afe58dc58
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22 FREM1	9.01e-06	189	66	5	90aae7e806882bebfad78a78e9a16cf56af3ecd4
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_proliferating_SM_(20)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	BLM FAT3 NAV2 LRRC7 IRS1	9.24e-06	190	66	5	e83fa8b711aa79a1767818474f1c193b674b1c31
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 PLAG1 NKTR GREB1 WNK1	9.72e-06	192	66	5	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	mild-low-quality_cells\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	ABCA2 NEK10 TTC14 NKTR ADAM22	1.10e-05	197	66	5	e4331969bd911d1ebb5453f40a7057297b5389b4
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHH2 WNK1 TRPV5 ADAM22 FREM1	1.16e-05	199	66	5	3cd6383c50ce342fe5c175e2e50784d634a90e80
ToppCell	390C-Myeloid-Macrophage-SPP1+_Macrophage_4\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	EPC1 FAM76B LRRC7 MED1	4.70e-05	134	66	4	9e12aac8f42790c2f104dfd61c87aa99fc7925f1
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22	7.86e-05	153	66	4	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22	8.69e-05	157	66	4	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22	9.13e-05	159	66	4	50d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUSP16 LRP5 CRYBG1 NKTR	9.81e-05	162	66	4	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	5'-Adult-Appendix-Hematopoietic-T_cells-ILC3\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	NEK10 SLC9A7 GAB3 PCDH9	1.00e-04	163	66	4	00e791358a7eb6c3e95f87afe22153845012e4a1
ToppCell	Adult-Immune-dendritic_cell\|Adult / Lineage, Cell type, age group and donor	LDLRAD2 LMNB1 NAV1 SLC9A7	1.05e-04	165	66	4	073f52698dac1fe4edd7410865f81b30e1c7196a
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	DUSP16 CRYBG1 NKTR WNK2	1.10e-04	167	66	4	83969c36ac44b96afc9aa09400a99fa2b487f7ff
ToppCell	390C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	TTLL11 SLC9A7 PCDH9 ARHGEF6	1.13e-04	168	66	4	d8f485f8459532a2cb0bef899e6569142cf75685
ToppCell	droplet-Limb_Muscle-MUSCLE-1m-Myeloid-unknown\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLM LMNB1 FAT3 WNK2	1.15e-04	169	66	4	bca5322880c09b78ef10d9dda6420a80c1ba7e62
ToppCell	390C-Lymphocytic-ILC-ILC-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	FOSL2 NAV2 OBI1 TP53BP1	1.24e-04	172	66	4	84d16cd7f618c94888920680bdc9e7130d73fd75
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLM PIK3C2B SLC9A7 WNK2	1.26e-04	173	66	4	8bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCell	facs-Marrow-KLS-3m-Lymphocytic-immature_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLM PIK3C2B SLC9A7 WNK2	1.26e-04	173	66	4	3e3c61468e703330788a10d850ef41a85680f86d
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_G2M\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BLM LMNB1 NAV2 SRGAP2	1.29e-04	174	66	4	72df66319f6efbd88ecf439013d97409fbf3cb52
ToppCell	PND28-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	BLM LMNB1 NAV2 SRGAP2	1.29e-04	174	66	4	c6087fd0e036ec7f40f0f8f17d1f6ce13ddb5235
ToppCell	normal_Lymph_Node-B_lymphocytes-GrB-secreting_B_cells\|B_lymphocytes / Location, Cell class and cell subclass	DMXL2 FOSL2 GAB3 IQCE	1.35e-04	176	66	4	d6e660df92a3d7dd5732171ee623763faf108476
ToppCell	droplet-Lung-30m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC9A7 PLAG1 SLC24A1 ADAM22	1.38e-04	177	66	4	4672cc75225a4a23b298afa8ce439628262519db
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA2 NAV2 WNK1 TRPV5	1.38e-04	177	66	4	c9e8149639551a4c8daa90fcb2b895fdcff2e2ba
ToppCell	ASK440-Immune-Mast_cell\|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq	NAV1 RGS10 ARHGEF6 FREM1	1.41e-04	178	66	4	dcefc4afca3a40d1bd44722e66bca6b45a6c6c55
ToppCell	BAL-Mild-cDC_4\|Mild / Compartment, Disease Groups and Clusters	ANKS6 KIAA0232 MUC16 MXI1	1.44e-04	179	66	4	68511e87b12b8253de7771e5ccfc5869248b8450
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 TRPV5 ADAM22 FREM1	1.44e-04	179	66	4	666072c0e8448dbaec1683d18368ec2502453f90
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 TRPV5 ADAM22 FREM1	1.54e-04	182	66	4	5f513bbb7125956eb528e3120de3fd776770a7c3
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 TRPV5 ADAM22 FREM1	1.54e-04	182	66	4	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-innate_lymphocytic-innate_lymphoid_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NEK10 FOSL2 CRYBG1 PCDH9	1.54e-04	182	66	4	b86690c109cdc16844a6cd2216c1bf2bf28efd45
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WNK1 TRPV5 ADAM22 FREM1	1.57e-04	183	66	4	2e831a4d99c6f983793df71c0994124c943c6da9
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Degenerative_Connecting_Tubule_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 WNK1 TRPV5 ADAM22	1.60e-04	184	66	4	9690d4290e70f9bda889754ffb30b0af1f7cb94b
ToppCell	Adult-Mesenchymal-matrix_fibroblast_2_cell-D231\|Adult / Lineage, Cell type, age group and donor	ADAMTSL1 NAV1 GREB1 PLEKHH2	1.63e-04	185	66	4	fb6bd7e849ecf4ed9cd9c4e2a946a2d12d62f804
ToppCell	COVID-19-Fibroblasts-Adventitial_FB\|COVID-19 / group, cell type (main and fine annotations)	ADAMTSL1 NAV2 GREB1 FREM1	1.63e-04	185	66	4	a5aebf2b9b05b550d021272731d68af9a6b1229d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 TRPV5 ADAM22 FREM1	1.63e-04	185	66	4	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 TRPV5 ADAM22 FREM1	1.70e-04	187	66	4	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)-Club_(non-nasal)_L.0.4.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ABCA2 DUSP16 MUC16 PLAG1	1.70e-04	187	66	4	f5a202d5f8eb57b57d80815ce98774e04c387383
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 IRS1 ADAM22 FREM1	1.74e-04	188	66	4	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CHEK2 PLEKHH2 FREM1	1.77e-04	189	66	4	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 TRPV5 ADAM22 FREM1	1.77e-04	189	66	4	8ff3c3232eff9de4b5c9b22ecb82bc509d773f58
ToppCell	LPS_only-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CHEK2 PLEKHH2 FREM1	1.77e-04	189	66	4	2a22b9fae70afb3dab8476f9c00e48a4df756410
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTSL1 CRYBG1 ADAM22 FREM1	1.81e-04	190	66	4	b3bccf4dd95e986db3cee324a6737f5fcc22e8e5
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 TRPV5 ADAM22 FREM1	1.81e-04	190	66	4	4836ea19308d2a96694f12ab0653b7ce7b101d2f
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CHEK2 PLEKHH2 FREM1	1.81e-04	190	66	4	841cd55861b43578d704418b9bc0af2e8b88323a
ToppCell	COVID-19-Myeloid-DC2\|COVID-19 / Condition, Lineage and Cell class	LDLRAD2 NAV1 SLC9A7 RGS10	1.85e-04	191	66	4	1304ab7b5713f29f3966ffc020ea1b52e8e2f375
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEK10 NAV2 PLEKHH2 PCDH9	1.85e-04	191	66	4	9032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CRYBG1 PCDH9 ADAM22 FREM1	1.85e-04	191	66	4	96b78b4e819ea6052334bfcbc7abbf35897df885
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NEK10 NAV2 PLEKHH2 PCDH9	1.85e-04	191	66	4	5717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 NAV2 PLEKHH2 FREM1	1.85e-04	191	66	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CHEK2 PLEKHH2 FREM1	1.88e-04	192	66	4	6f4ef24dab544681304b7f8a9dc073e7edaa4cf5
ToppCell	COVID-19-kidney-CNT\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CRYBG1 TRPV5 ADAM22 FREM1	1.88e-04	192	66	4	760c6b9628de9693034b00c5025c5c4df94bb2e8
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	FAT3 NAV2 PLEKHH2 FREM1	1.88e-04	192	66	4	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CHEK2 PLEKHH2 FREM1	1.88e-04	192	66	4	dcd924d6eb67d33ee9f5d3e8ab6e1d4283d6b708
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA2 NAV2 WNK1 PCDH9	1.88e-04	192	66	4	32e4a180037e516c5cc798cd9dada9385e0f43ae
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FAT3 NAV2 PLEKHH2 FREM1	1.92e-04	193	66	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	LRP5 PLAG1 GREB1 WNK2	1.92e-04	193	66	4	503a979328c68b096680b71359a26f02fafdff35
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	HIVEP1 PLAG1 NKTR WNK1	1.92e-04	193	66	4	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	LRRC7 IRS1 GREB1 FREM1	1.92e-04	193	66	4	e2b455387d1de7812305200a2041a0f4759a6f54
ToppCell	COVID-19-Myeloid-DC2\|Myeloid / Condition, Lineage and Cell class	LDLRAD2 NAV1 SLC9A7 RGS10	1.92e-04	193	66	4	5f3f6db3d3de887d004662d229f42549601efa81
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	FAT3 PLEKHH2 ADAM22 FREM1	1.96e-04	194	66	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 CHEK2 PLEKHH2 FREM1	1.96e-04	194	66	4	60622bd2f75bfe4c37f721cb12f03dab33f2f58d
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM1_(8)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FAT3 IRS1 GREB1 FREM1	1.96e-04	194	66	4	fb80a0271ccb1cb3f954ebcf2c5945cb6adb6b8c
ToppCell	nucseq-Immune-Immune_Myeloid-Myeloid_Dendritic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	SLC9A7 CRYBG1 SRGAP2 RGS10	1.96e-04	194	66	4	bde6830a281f7cd7fd1733e40a41ddd2673ba88e
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAT3 LRRC7 PLEKHH2 FREM1	1.96e-04	194	66	4	89b706af2b25991fc2707eb24f49ba6ff3ae01f7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	FAT3 PLEKHH2 ADAM22 FREM1	2.00e-04	195	66	4	0e55fa5b3cbeb7baee3d4ac272a3bf80381ec937
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell\|Adult / Lineage, Cell type, age group and donor	FAT3 NAV2 PLEKHH2 FREM1	2.00e-04	195	66	4	61c9e09fc84d1012e472185d70ad0a06cee30d6e
ToppCell	Adult-Mesenchymal-matrix_fibroblast_1_cell-D122\|Adult / Lineage, Cell type, age group and donor	FAT3 NAV2 PLEKHH2 FREM1	2.00e-04	195	66	4	aa0add081881d349099d12efca5cdee098038d4e
ToppCell	moderate-Lymphoid-Treg\|Lymphoid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	DUSP16 EPC1 TTC14 NKTR	2.04e-04	196	66	4	9152f4a8a27ff4ee28f231c5ad00eb2edd9ea6da
ToppCell	background-Hepatic_Stellate_cells\|background / Sample and Cell Type and Tumor Cluster (all cells)	ADAMTSL1 FAT3 PLEKHH2 PCDH9	2.12e-04	198	66	4	bd11b0e9e80449aab979a02c1023e0638c431c7c
ToppCell	(02)_MMP9/10+-(2)_GFP_FOXI1\|(02)_MMP9/10+ / shred by cell type by condition	FAT3 CRYBG1 IRS1 MXI1	2.16e-04	199	66	4	18a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell	distal-Hematologic-Myeloid_Dendritic_Type_2-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	LDLRAD2 LMNB1 SLC9A7 RGS10	2.16e-04	199	66	4	83400b10974ef4dafe8223562cdcdc58eef92428
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic-Fibro_alveolar\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT3 NAV2 PLEKHH2 FREM1	2.20e-04	200	66	4	e8462395fee0a532d1e7ec7f1795f28c42af6541
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial-Proteoglycan-expressing_cell\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	NAV2 TRAPPC10 PLAG1 PLEKHH2	2.20e-04	200	66	4	aafe594c88710f8c53d59667cdac5035e08f5511
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Neuronal-Interneuron\|10w / Sample Type, Dataset, Time_group, and Cell type.	NAV1 LRRC7 SRGAP2 PCDH9	2.20e-04	200	66	4	f5c63ef52bd7a898cf009b8bf9b2f7f4890d1c9b
ToppCell	Sepsis-Bac-SEP-Myeloid-cDC1\|Bac-SEP / Disease, condition lineage and cell class	ANKS6 NAV1 SLC9A7 RGS10	2.20e-04	200	66	4	cd381644fd8b8674a017d267bfbb00f2668294ae
ToppCell	Bronchial-NucSeq-Stromal-Fibroblastic\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FAT3 NAV2 PLEKHH2 FREM1	2.20e-04	200	66	4	cae972324d1dfea6efeaf6013f265c7c6bb48db4
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	MYCBP2 CHEK2 PLEKHH2 FREM1	2.20e-04	200	66	4	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19-Neuroepithelial\|GW19 / Sample Type, Dataset, Time_group, and Cell type.	NAV2 TRAPPC10 PLAG1 PLEKHH2	2.20e-04	200	66	4	a6f0f5f644b7262878b0b9d4d90ee407c4124dd9
ToppCell	Tracheal-NucSeq-Stromal-Fibroblastic-Fibro_adventitial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ADAMTSL1 NAV2 NAV1 FREM1	2.20e-04	200	66	4	0c25d56292b9e5fefa4521b72635449be1ffd6fe
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 FOSL2 IRS1 GREB1 SLC24A1	6.65e-07	172	66	7	6993_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 UBAP2L FOSL2 IRS1 GREB1	7.47e-07	175	66	7	7236_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 FOSL2 IRS1 GREB1	1.14e-05	174	66	6	5945_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 FOSL2 IRS1 GREB1	1.17e-05	175	66	6	5935_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 FOSL2 IRS1 GREB1 CLOCK	1.21e-05	176	66	6	6932_DN
Drug	Flupentixol dihydrochloride cis-(Z) [2413-38-9]; Down 200; 7.8uM; HL60; HT_HG-U133A	WWC2 UBN1 LMNB1 PLAG1 WNK1 RGS10	1.82e-05	189	66	6	1288_DN
Drug	Securinine [5610-40-2]; Up 200; 18.4uM; MCF7; HT_HG-U133A	DMXL2 FOSL2 NAV2 GREB1 SLC24A1 ADAM22	1.98e-05	192	66	6	3470_UP
Drug	felodipine; Down 200; 10uM; MCF7; HT_HG-U133A_EA	ABCA2 LMNB1 PCDH9 ADAM22 ARHGEF6 IQCE	2.04e-05	193	66	6	965_DN
Drug	Atovaquone [95233-18-4]; Up 200; 11uM; HL60; HT_HG-U133A	DMXL2 FOSL2 LRP5 SLC24A1 ADAM22 RGS10	2.17e-05	195	66	6	2480_UP
Drug	(-)-depudecin; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SRSF4 LMNB1 UBAP2L FOSL2 PCDH9 ARHGEF6	2.23e-05	196	66	6	982_DN
Drug	Benzocaine [94-09-7]; Up 200; 24.2uM; MCF7; HT_HG-U133A	WWC2 ABCA2 LMNB1 KIAA0232 SLC24A1 ADAM22	2.43e-05	199	66	6	2822_UP
Drug	Azathioprine [446-86-6]; Down 200; 14.4uM; PC3; HG-U133A	PHKA2 DMXL2 UBAP2L TRAPPC10 ARHGEF6 IQCE	2.43e-05	199	66	6	1945_DN
Drug	3-O-methyl-6-deoxy-d-talose	ABCA2 LRP5	4.95e-05	4	66	2	CID000150840
Drug	AC1L1EUW	BLM CHEK2 TP53BP1	8.93e-05	30	66	3	CID000002960
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 FOSL2 IRS1 GREB1	1.18e-04	165	66	5	6085_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 TMEM39B IRS1 GREB1	1.18e-04	165	66	5	2835_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 FOSL2 IRS1 GREB1	1.21e-04	166	66	5	2247_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 LMNB1 FOSL2 IRS1 GREB1	1.21e-04	166	66	5	7324_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 FOSL2 IRS1 GREB1	1.35e-04	170	66	5	7043_DN
Drug	SAHA; Down 200; 10uM; MCF7; HT_HG-U133A_EA	HIVEP1 LMNB1 FOSL2 IRS1 GREB1	1.39e-04	171	66	5	1000_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 IRS1 GREB1	1.39e-04	171	66	5	2777_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 IRS1 GREB1	1.39e-04	171	66	5	4954_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 FOSL2 IRS1 GREB1	1.43e-04	172	66	5	4112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 IRS1 GREB1	1.47e-04	173	66	5	5336_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 IRS1 GREB1	1.51e-04	174	66	5	3462_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 TMEM39B IRS1 GREB1	1.51e-04	174	66	5	5693_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A_EA	HIVEP1 SRSF4 FOSL2 IRS1 GREB1	1.55e-04	175	66	5	1014_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 FOSL2 IRS1 GREB1	1.55e-04	175	66	5	6891_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 TMEM39B IRS1 GREB1	1.59e-04	176	66	5	6784_DN
Drug	trichostatin A ; Down 200; 1uM; MCF7; HT_HG-U133A_EA	SRSF4 LMNB1 TENT4A IRS1 GREB1	1.59e-04	176	66	5	981_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	HIVEP1 LMNB1 FOSL2 IRS1 GREB1	1.59e-04	176	66	5	5976_DN
Drug	trichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 FOSL2 IRS1 GREB1	1.63e-04	177	66	5	6434_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	SRSF4 LMNB1 TMEM39B IRS1 GREB1	1.63e-04	177	66	5	5308_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 LMNB1 FOSL2 IRS1	1.68e-04	178	66	5	1471_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	SRSF4 LMNB1 IRS1 GREB1 CLOCK	1.68e-04	178	66	5	992_DN
Drug	Etifenin [63245-28-3]; Down 200; 12.4uM; PC3; HT_HG-U133A	UBN1 MYCBP2 NKTR MED1 WNK1	1.68e-04	178	66	5	3998_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	SRSF4 LMNB1 TENT4A IRS1 GREB1	1.68e-04	178	66	5	1112_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A	HIVEP1 SRSF4 IRS1 GREB1 SLC24A1	1.68e-04	178	66	5	6276_DN
Drug	Sulfaphenazole [526-08-9]; Down 200; 12.8uM; MCF7; HT_HG-U133A	WWC2 UBN1 NKTR MED1 WNK1	2.01e-04	185	66	5	1673_DN
Drug	Amethopterin (R,S) [59-05-2]; Down 200; 8.8uM; MCF7; HT_HG-U133A	PHKA2 LMNB1 U2SURP SRGAP2 GREB1	2.06e-04	186	66	5	5000_DN
Drug	Mianserine hydrochloride [21535-47-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A	U2SURP GREB1 WNK1 PCDH9 ADAM22	2.22e-04	189	66	5	2231_UP
Drug	Sulfamethazine sodium salt [1981-58-4]; Down 200; 13.4uM; PC3; HT_HG-U133A	UBAP2L SLC9A7 NKTR WNK1 RGS10	2.27e-04	190	66	5	4322_DN
Drug	Methotrexate [59-05-2]; Down 200; 8.8uM; PC3; HT_HG-U133A	U2SURP SRGAP2 MED1 WNK1 IQCE	2.27e-04	190	66	5	6318_DN
Drug	Flavoxate hydrochloride [3717-88-2]; Down 200; 9.4uM; MCF7; HT_HG-U133A	MYCBP2 FOSL2 U2SURP TRAPPC10 GREB1	2.27e-04	190	66	5	7405_DN
Drug	Propofol [2078-54-8]; Down 200; 22.4uM; MCF7; HT_HG-U133A	DMXL2 SLC9A7 GREB1 ADAM22 RGS10	2.33e-04	191	66	5	3386_DN
Drug	Norethynodrel [68-23-5]; Up 200; 13.4uM; MCF7; HT_HG-U133A	FOSL2 NAV2 GREB1 ADAM22 RGS10	2.38e-04	192	66	5	1696_UP
Drug	Cyanocobalamin [68-19-9]; Down 200; 3uM; MCF7; HT_HG-U133A	UBN1 GREB1 WNK1 ADAM22 RGS10	2.38e-04	192	66	5	3252_DN
Drug	Sulfamethoxazole [723-46-6]; Down 200; 15.8uM; HL60; HT_HG-U133A	FOSL2 TRAPPC10 SRGAP2 WNK1 RGS10	2.38e-04	192	66	5	2335_DN
Drug	ICI 182,780; Down 200; 1uM; MCF7; HG-U133A	PHKA2 UBN1 GREB1 SLC24A1 ADAM22	2.38e-04	192	66	5	367_DN
Drug	Letrozole [112809-51-5]; Down 200; 14uM; PC3; HT_HG-U133A	ABCA2 UBAP2L FOSL2 WNK1 ADAM22	2.44e-04	193	66	5	4240_DN
Drug	Vitamin K2 [11032-49-8]; Up 200; 9uM; MCF7; HT_HG-U133A	LMNB1 SLC9A7 SLC24A1 PCDH9 ADAM22	2.44e-04	193	66	5	3880_UP
Drug	Methoxy-6-harmalan [3589-73-9]; Down 200; 18.6uM; MCF7; HT_HG-U133A	PIK3C2B GREB1 SLC24A1 WNK1 ADAM22	2.56e-04	195	66	5	5455_DN
Drug	5194442; Up 200; 20uM; MCF7; HT_HG-U133A	WWC2 ABCA2 KIAA0232 PCDH9 MXI1	2.56e-04	195	66	5	6558_UP
Drug	Ethopropazine hydrochloride [1094-08-2]; Down 200; 11.4uM; MCF7; HT_HG-U133A	DMXL2 ABCA2 FOSL2 SLC9A7 PCDH9	2.56e-04	195	66	5	3376_DN
Drug	Parbendazole [14255-87-9]; Up 200; 16.2uM; PC3; HT_HG-U133A	ABCA2 NAV2 GREB1 WNK1 RGS10	2.62e-04	196	66	5	4535_UP
Drug	Methylergometrine maleate [113-42-8]; Down 200; 8.8uM; MCF7; HT_HG-U133A	ABCA2 LMNB1 UBAP2L PCDH9 IQCE	2.62e-04	196	66	5	3222_DN
Drug	Iopamidol [60166-93-0]; Up 200; 5.2uM; MCF7; HT_HG-U133A	TRAPPC10 GREB1 WNK1 PCDH9 ADAM22	2.62e-04	196	66	5	3473_UP
Drug	Khellin [82-02-0]; Down 200; 15.4uM; MCF7; HT_HG-U133A	PIK3C2B FOSL2 MED1 RGS10 IQCE	2.62e-04	196	66	5	4987_DN
Drug	Diflorasone Diacetate [33564-31-7]; Down 200; 8uM; MCF7; HT_HG-U133A	DMXL2 NAV2 TRAPPC10 LRP5 ADAM22	2.62e-04	196	66	5	2798_DN
Drug	Trioxsalen [3902-71-4]; Down 200; 17.6uM; HL60; HT_HG-U133A	PHKA2 DMXL2 HIVEP1 TRAPPC10 SLC24A1	2.62e-04	196	66	5	2516_DN
Drug	Zomepirac sodium salt [64092-48-4]; Down 200; 12.8uM; MCF7; HT_HG-U133A	FOSL2 WNK1 PCDH9 RGS10 IQCE	2.69e-04	197	66	5	6815_DN
Drug	genistein; Up 200; 10uM; MCF7; HT_HG-U133A	ABCA2 FOSL2 NAV2 GREB1 RGS10	2.69e-04	197	66	5	6952_UP
Drug	Enoxacin [74011-58-8]; Down 200; 12.4uM; MCF7; HT_HG-U133A	WWC2 DMXL2 PIK3C2B NKTR WNK1	2.69e-04	197	66	5	5616_DN
Drug	Alclometasone dipropionate [667634-13-2]; Down 200; 7.6uM; HL60; HT_HG-U133A	DMXL2 ABCA2 PIK3C2B CLOCK IQCE	2.69e-04	197	66	5	2532_DN
Drug	Phenylpropanolamine hydrochloride [154-41-6]; Up 200; 21.4uM; HL60; HG-U133A	ABCA2 PIK3C2B TMEM39B MED1 OBI1	2.69e-04	197	66	5	1602_UP
Drug	Adiphenine hydrochloride [50-42-0]; Up 200; 11.4uM; MCF7; HT_HG-U133A	ABCA2 LMNB1 FOSL2 CHEK2 NAV2	2.69e-04	197	66	5	1709_UP
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	PHKA2 ABCA2 GREB1 RGS10 TP53BP1	2.69e-04	197	66	5	7201_DN
Drug	HA-1077 dihydrochloride; Down 200; 10uM; PC3; HG-U133A	DMXL2 PIK3C2B FOSL2 SLC9A7 IQCE	2.75e-04	198	66	5	436_DN
Drug	Capsaicin [404-86-4]; Down 200; 13uM; MCF7; HT_HG-U133A	PHKA2 ABCA2 LMNB1 UBAP2L ADAM22	2.75e-04	198	66	5	5673_DN
Drug	C75; Up 200; 10uM; PC3; HT_HG-U133A	PHKA2 UBAP2L WNK1 ADAM22 IQCE	2.75e-04	198	66	5	6428_UP
Drug	Ajmaline [4360-12-7]; Down 200; 12.2uM; MCF7; HT_HG-U133A	FOSL2 NKTR GREB1 OBI1 RGS10	2.75e-04	198	66	5	7484_DN
Drug	Fusidic acid sodium salt [751-94-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A	PHKA2 LMNB1 MED1 SLC24A1 TP53BP1	2.81e-04	199	66	5	5353_DN
Drug	Hydroxyzine dihydrochloride [2192-20-3]; Down 200; 9uM; MCF7; HT_HG-U133A	ABCA2 ADAM22 RGS10 TP53BP1 IQCE	2.81e-04	199	66	5	5006_DN
Drug	Tracazolate hydrochloride [41094-88-6]; Down 200; 11.8uM; MCF7; HT_HG-U133A	WWC2 ABCA2 LMNB1 PCDH9 RGS10	2.81e-04	199	66	5	7339_DN
Drug	Idazoxan hydrochloride [79944-56-2]; Down 200; 16.6uM; MCF7; HT_HG-U133A	ABCA2 LMNB1 U2SURP TRAPPC10 PCDH9	2.81e-04	199	66	5	5347_DN
Drug	estradiol, USP; Up 200; 0.01uM; MCF7; HT_HG-U133A	ABCA2 FOSL2 GREB1 SLC24A1 ADAM22	2.88e-04	200	66	5	5601_UP
Drug	Deferoxamine mesylate [138-14-7]; Up 200; 6uM; PC3; HT_HG-U133A	COL17A1 PLAG1 GREB1 MUC6 ADAM22	2.88e-04	200	66	5	3760_UP
Disease	pseudohypoaldosteronism (implicated_via_orthology)	WNK1 WNK2	6.91e-05	6	64	2	DOID:4479 (implicated_via_orthology)
Disease	Malignant tumor of prostate	CHEK2 MXI1	1.65e-04	9	64	2	cv:C0376358
Disease	platelet component distribution width	TENT4A KIAA0232 U2SURP EPC1 CHEK2 IRS1 WNK1 IQCE	2.21e-04	755	64	8	EFO_0007984
Disease	X-Linked Csnb	SLC24A1 GPR179	3.01e-04	12	64	2	C3711543
Disease	Night blindness, congenital stationary, type 1	SLC24A1 GPR179	3.01e-04	12	64	2	C3501847
Disease	Night Blindness, Congenital Stationary, Type 1A	SLC24A1 GPR179	3.01e-04	12	64	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	SLC24A1 GPR179	3.01e-04	12	64	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	SLC24A1 GPR179	3.01e-04	12	64	2	C1848172
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	SLC24A1 GPR179	3.01e-04	12	64	2	C1850362
Disease	Cone-rod synaptic disorder, congenital nonprogressive	SLC24A1 GPR179	3.56e-04	13	64	2	C4041558
Disease	early cardiac repolarization measurement	MYCBP2 LRP5	4.14e-04	14	64	2	EFO_0004885
Disease	Night blindness, congenital stationary	SLC24A1 GPR179	6.17e-04	17	64	2	C0339535
Disease	body fat percentage	DMXL2 HIVEP1 UBN1 LMNB1 IRS1 SRGAP2	6.61e-04	488	64	6	EFO_0007800
Disease	monocyte measurement	LMNB1 FAM76B MXI1	7.63e-04	82	64	3	EFO_0803547
Disease	diet measurement, HOMA-B	FAT3 DUSP16	7.73e-04	19	64	2	EFO_0004469, EFO_0008111
Disease	serum gamma-glutamyl transferase measurement	WWC2 FOSL2 CHEK2 NAV2 SLC9A7 MUC6 TP53BP1 MXI1	7.85e-04	914	64	8	EFO_0004532
Disease	osteoporosis (biomarker_via_orthology)	LRP5 IRS1	1.04e-03	22	64	2	DOID:11476 (biomarker_via_orthology)
Disease	Disorder of eye	LRP5 SLC24A1 FREM1 GPR179	1.17e-03	212	64	4	C0015397
Disease	asthma	FLG DMXL2 HIVEP1 NEK10 MUC16 SRGAP2 MED1	1.19e-03	751	64	7	MONDO_0004979
Disease	Neoplasm of the genitourinary tract	CHEK2 MXI1	1.24e-03	24	64	2	cv:C0042065
Disease	colon adenocarcinoma (is_marker_for)	SRSF4 FOSL2	1.35e-03	25	64	2	DOID:234 (is_marker_for)
Disease	cancer	UBN1 PIK3C2B NEK10 FAM76B TRPV5	1.77e-03	400	64	5	MONDO_0004992
Disease	presubiculum volume	ADAMTSL1 WNK2	2.07e-03	31	64	2	EFO_0009400

Protein segments in the cluster

Peptide	Gene	Start	Entry
LLSTDASHSRGSSSS	COL17A1	1281	Q9UMD9
CSTSTQSKSSSGSAH	EPC1	566	Q9H2F5
SVSSLGHSSATSASL	CHD8	2456	Q9HCK8
LSKTSSSSCSAHSSF	ARHGEF6	556	Q15052
SASSSKKRSNGLSHS	ADAM22	796	Q9P0K1
TTTSSIASSLSHAGR	DMXL2	286	Q8TDJ6
SSRKSGTRHTQNSSS	FLG	676	P20930
QSSHSSSGTLSSLET	CHEK2	51	O96017
SDGSSSSSHQSLKST	RGS10	21	O43665
HSATGKRTTTAASTR	IQCE	621	Q6IPM2
IRSGSTHSTGTKTFS	MUC16	2801	Q8WXI7
SRSSFSTAKTSTSLH	MUC6	1736	Q6W4X9
SQTGSTDAHTSRSLT	LDLRAD2	221	Q5SZI1
SLLTRGSSSTSLHNS	SLC24A1	651	O60721
GSSSTSLHNSTIRST	SLC24A1	656	O60721
RSRSHDSASSSLSSK	GREB1	1121	Q4ZG55
AKSSSVDSSHTSGRL	GPR179	906	Q6PRD1
SNPLLSSKSRSTSSH	LRRC7	791	Q96NW7
SSASSLLTAHAASSS	GAB3	141	Q8WWW8
NHVTGASSSSSSSTK	LRP5	1476	O75197
ASSSVSISHSASATG	LMNB1	426	P20700
KHVSGFSSSLRTSST	ADAMTSL1	1136	Q8N6G6
ASLSSSSSGAASLKS	NEK10	841	Q6ZWH5
IHTGSSSSSSSGSVK	KIAA0232	346	Q92628
SKRSSTSSDHFSASE	PCDH9	981	Q9HC56
SSSSTTSGSFHLERR	FREM1	1881	Q5H8C1
TSSSSHLAKPSSSRL	OBI1	306	Q5W0B1
RKSLGSSHSNSSSSS	FAM76B	146	Q5HYJ3
SSSSSEDVKRHSSAS	IRS1	1131	P35568
GRSKSRCTSTLSSHT	PLEKHH2	296	Q8IVE3
RLHKSPSLSSSSSSS	TENT4A	81	Q5XG87
TLSFASRTHTLKSSG	PIK3C2B	1351	O00750
TKSSSIIGSSSASHT	BLM	1371	P54132
SKRLHSVRTSSSGTA	DUSP16	481	Q9BY84
SVSLSLHNSRGTSSS	FAT3	4501	Q8TDW7
SKAHRRSSSSGDQSS	FOSL2	301	P15408
TSGSHLDRSTVSSFS	ABCA2	136	Q9BZC7
SVSSSSSHRQSKSSG	ANKS6	751	Q68DC2
FNSSSTSHSSLKSPS	CRYBG1	906	Q9Y4K1
SSKSEGSSSSKLSSS	MED1	1116	Q15648
AASSSAHSSKSARSS	PHKA2	1026	P46019
SCLKRNASSSSSSHS	nan	386	A6NNC1
SSLNSITSHSSIGSS	NAV1	1186	Q8NEY1
SRSGSSKSSHSKSRS	SRSF4	206	Q08170
IHTSSKTALRTGSSD	TRIM42	111	Q8IWZ5
GRACKSSGSSSTSTH	TMEM150A	246	Q86TG1
GSSRSRTASKSSSHS	NKTR	531	P30414
RHSSSSSSLASSEGK	NAV2	631	Q8IVL1
ASTSGKSELSSKHSR	MYCBP2	2726	O75592
SRSHSKSGSSTSSRS	SRSF8	206	Q9BRL6
KASSKTRSSDVHSSG	U2SURP	11	O15042
SASSRSSRKSSHTAV	CLOCK	431	O15516
HSLSAAFTSSLSTST	PLAG1	476	Q6DJT9
HSDSASTGSKRTFSS	TTLL11	446	Q8NHH1
EKSSSHTSLFSGSSS	WWC2	141	Q6AWC2
SSTSSGRTSTSTLLH	UBAP2L	706	Q14157
RSDSHGLSSSLTDSS	SRGAP2	851	O75044
ESVSSSSSSSSSGHK	TTC14	486	Q96N46
SSKASSLHRTSSGTS	TP53BP1	1306	Q12888
TSGGLSASSSSSHKT	UBN1	861	Q9NPG3
SSISKHGVSSGSSSS	UBN1	906	Q9NPG3
KTSHSSTTGLAFSLS	WNK1	1531	Q9H4A3
CLGKEHSSRSSTSSL	WNK2	2116	Q9Y3S1
SSSLKSRGSVHSACS	TRAPPC10	1201	P48553
SSSHTASTSLEGSRR	SLC9A7	676	Q96T83
LSRESSLSHTSSFSA	HIVEP1	1306	P15822
SSGSHTSSASVTSVR	TMEM39B	26	Q9GZU3
SSLSRTASQSSSHRG	TRPV5	686	Q9NQA5
KHSSGSSNTSTANRS	MXI1	56	P50539