Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	epithelial cell development	ZDHHC21 ROBO4 SHROOM3 ABCA12 EXPH5 XBP1 CCDC88C FASN PTPRS PARD3 ARHGEF26	1.51e-06	269	134	11	GO:0002064
Domain	FN3	ROBO4 TNC INSRR PTPRS IL21R TRIM36 MDGA1 MYBPC2	5.15e-05	185	132	8	SM00060
Domain	FN3	ROBO4 TNC INSRR PTPRS IL21R TRIM36 MDGA1 MYBPC2	8.60e-05	199	132	8	PS50853
Domain	FN3_dom	ROBO4 TNC INSRR PTPRS IL21R TRIM36 MDGA1 MYBPC2	1.21e-04	209	132	8	IPR003961
Domain	Ago_hook	TNRC6B TNRC6A	1.48e-04	3	132	2	PF10427
Domain	ASD1	SHROOM3 SHROOM2	1.48e-04	3	132	2	PF08688
Domain	ASD1_dom	SHROOM3 SHROOM2	1.48e-04	3	132	2	IPR014800
Domain	TNRC6_PABC-bd	TNRC6B TNRC6A	1.48e-04	3	132	2	IPR032226
Domain	Argonaute_hook_dom	TNRC6B TNRC6A	1.48e-04	3	132	2	IPR019486
Domain	TNRC6-PABC_bdg	TNRC6B TNRC6A	1.48e-04	3	132	2	PF16608
Domain	ASD1	SHROOM3 SHROOM2	1.48e-04	3	132	2	PS51306
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B4	2.95e-04	4	132	2	IPR022141
Domain	ATP_Ca_trans_C	ATP2B2 ATP2B4	2.95e-04	4	132	2	PF12424
Domain	Shroom_fam	SHROOM3 SHROOM2	2.95e-04	4	132	2	IPR027685
Domain	ASD2_dom	SHROOM3 SHROOM2	2.95e-04	4	132	2	IPR014799
Domain	ASD2	SHROOM3 SHROOM2	2.95e-04	4	132	2	PF08687
Domain	ASD2	SHROOM3 SHROOM2	2.95e-04	4	132	2	PS51307
Domain	P-type_ATPase_IIB	ATP2B2 ATP2B4	2.95e-04	4	132	2	IPR006408
Domain	Ig-like_fold	ROBO4 HSPG2 TNC SIGLEC9 INSRR IL18RAP PLXNC1 PTPRS IL21R PRKAB1 SIGLEC10 TRIM36 MDGA1 MYBPC2	4.77e-04	706	132	14	IPR013783
Domain	-	ROBO4 HSPG2 TNC SIGLEC9 INSRR IL18RAP PLXNC1 PTPRS IL21R SIGLEC10 TRIM36 MDGA1 MYBPC2	8.47e-04	663	132	13	2.60.40.10
Domain	fn3	ROBO4 TNC INSRR PTPRS TRIM36 MYBPC2	1.03e-03	162	132	6	PF00041
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SHROOM3 EXPH5 MATK USP43 APC KIAA0753 RUSC2 GRIP1 CCDC88C KSR1 WWC2 EIF4B RACGAP1 CRYBG3 GNAS MAPK4 PARD3 SRRM2 OBI1	1.81e-09	861	139	19	36931259
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HSPG2 SHROOM3 RHBDF1 HECTD4 IRAK1 GEMIN5 EML3 RABL6 ORC1 CCDC88C FASN TKFC ARVCF PTPRS IL17RE TMEM132A KBTBD11 SPEN LTBP4 PCNT	1.84e-08	1105	139	20	35748872
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	PRUNE2 EXPH5 DHX38 ZFC3H1 KIAA0753 CCDC88C ADAMTS9 POP1 TMEM132A PHF14 MINAR1 POM121B FAM135A	1.03e-07	493	139	13	15368895
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	SHROOM3 APC RHPN2 RACGAP1 PARD3 SRRM2 GPRIN2	1.88e-07	102	139	7	15778465
Pubmed	The Functional Proximal Proteome of Oncogenic Ras Includes mTORC2.	RHBDF1 EXPH5 USP43 PARP14 CDKL5 ARVCF RHPN2 PLXNC1 STON2 PARD3 ARHGEF26 FAM135A ATP2B4	5.23e-07	569	139	13	30639242
Pubmed	A Global Analysis of the Receptor Tyrosine Kinase-Protein Phosphatase Interactome.	ROBO4 TNC DHX38 INSRR IRAK1 MUC16 WWC2 MTMR11 EIF4B SRRM2 SPEN	1.10e-06	420	139	11	28065597
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	EXPH5 APC IRAK1 TNRC6B RABL6 TNRC6A CRYBG3 PARD3 FAM135A	1.23e-06	263	139	9	34702444
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHROOM3 HECTD4 APC TRIOBP TNRC6B SYNPO CCDC88C ARVCF PTPRS STON2 RACGAP1 BRSK1 PARD3 ARHGEF26 ATP2B4 PCNT	1.66e-06	963	139	16	28671696
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	HSPG2 RHBDF1 TNC HECTD4 TNRC6B ADAMTS9 POP1 NOS2 OBI1 SENP7	2.19e-06	363	139	10	14691545
Pubmed	Oncogenic PIK3CA induces centrosome amplification and tolerance to genome doubling.	APC BMPR1B PCNT	3.45e-06	8	139	3	29170395
Pubmed	Brn3a and Nurr1 mediate a gene regulatory pathway for habenula development.	NGB RFX4 PLXNC1 MINAR1 FGF14 TRIM36 ARMH4	5.00e-06	166	139	7	19906978
Pubmed	Human Immunodeficiency Virus Type 1 Vpr Mediates Degradation of APC1, a Scaffolding Component of the Anaphase-Promoting Complex/Cyclosome.	DHX38 APC IRAK1 TNRC6B TNRC6A RACGAP1 INTS9 GNAS	6.29e-06	242	139	8	34011540
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	PDCD2 SHROOM3 APC TNRC6B KIAA0753 GRIP1 CCDC88C KSR1 TNRC6A PARD3	1.33e-05	446	139	10	24255178
Pubmed	Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.	SHROOM3 APC MUC16 TNRC6B ZC3HC1 RABL6 CDKL5 BBX TNRC6A KBTBD11 PARD3 SPEN FAM135A	1.54e-05	777	139	13	35844135
Pubmed	Hearing loss associated with the modifier of deaf waddler (mdfw) locus corresponds with age-related hearing loss in 12 inbred strains of mice.	CDH23 ATP2B2	1.59e-05	2	139	2	11423214
Pubmed	Patterns of distribution of oxygen-binding globins, neuroglobin and cytoglobin in human retina.	NGB CYGB	1.59e-05	2	139	2	19001220
Pubmed	Role of GW182 protein in the cell.	TNRC6B TNRC6A	1.59e-05	2	139	2	29791863
Pubmed	Allosteric regulation and temperature dependence of oxygen binding in human neuroglobin and cytoglobin. Molecular mechanisms and physiological significance.	NGB CYGB	1.59e-05	2	139	2	15299006
Pubmed	Cytoglobin and neuroglobin in the human brainstem and carotid body.	NGB CYGB	1.59e-05	2	139	2	23835959
Pubmed	Hyperthermal stability of neuroglobin and cytoglobin.	NGB CYGB	1.59e-05	2	139	2	15819897
Pubmed	Divergent distribution of cytoglobin and neuroglobin in the murine eye.	NGB CYGB	1.59e-05	2	139	2	15663964
Pubmed	Modification of human hearing loss by plasma-membrane calcium pump PMCA2.	CDH23 ATP2B2	1.59e-05	2	139	2	15829536
Pubmed	Neuroglobin and cytoglobin expression in the human brain.	NGB CYGB	1.59e-05	2	139	2	23160832
Pubmed	Structural characterization of the proximal and distal histidine environment of cytoglobin and neuroglobin.	NGB CYGB	1.59e-05	2	139	2	16201751
Pubmed	Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.	ATP2B2 ATP2B4	1.59e-05	2	139	2	1313367
Pubmed	Neuroglobin and cytoglobin expression in mice. Evidence for a correlation with reactive oxygen species scavenging.	NGB CYGB	1.59e-05	2	139	2	17286577
Pubmed	BMPR1B up-regulation via a miRNA binding site variation defines endometriosis susceptibility and CA125 levels.	MUC16 BMPR1B	1.59e-05	2	139	2	24339876
Pubmed	Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.	ATP2B2 ATP2B4	1.59e-05	2	139	2	22252018
Pubmed	Lack of inducible nitric oxide synthase promotes intestinal tumorigenesis in the Apc(Min/+) mouse.	APC NOS2	1.59e-05	2	139	2	11606502
Pubmed	Exome sequencing identified rare variants in genes HSPG2 and ATP2B4 in a family segregating developmental dysplasia of the hip.	HSPG2 ATP2B4	1.59e-05	2	139	2	28327142
Pubmed	Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.	ATP2B2 ATP2B4	1.59e-05	2	139	2	25690014
Pubmed	Tissue-Specific Downregulation of Fatty Acid Synthase Suppresses Intestinal Adenoma Formation via Coordinated Reprograming of Transcriptome and Metabolism in the Mouse Model of Apc-Driven Colorectal Cancer.	APC FASN	1.59e-05	2	139	2	35742953
Pubmed	The role of NO synthases in arginine-dependent small intestinal and colonic carcinogenesis.	APC NOS2	1.59e-05	2	139	2	16329147
Pubmed	Risk and risk reduction involving arginine intake and meat consumption in colorectal tumorigenesis and survival.	APC NOS2	1.59e-05	2	139	2	17096347
Pubmed	mdfw: a deafness susceptibility locus that interacts with deaf waddler (dfw).	CDH23 ATP2B2	1.59e-05	2	139	2	9325047
Pubmed	Genetic and functional analysis of SHROOM1-4 in a Chinese neural tube defect cohort.	SHROOM3 SHROOM2	1.59e-05	2	139	2	29423651
Pubmed	Electron transfer function versus oxygen delivery: a comparative study for several hexacoordinated globins across the animal kingdom.	NGB CYGB	1.59e-05	2	139	2	21674044
Pubmed	Fasting exacerbates hepatic growth differentiation factor 15 to promote fatty acid β-oxidation and ketogenesis via activating XBP1 signaling in liver.	GDF15 XBP1	1.59e-05	2	139	2	29482168
Pubmed	Identification of Siglec-9 as the receptor for MUC16 on human NK cells, B cells, and monocytes.	SIGLEC9 MUC16	1.59e-05	2	139	2	20497550
Pubmed	A new Atp2b2 deafwaddler allele, dfw(i5), interacts strongly with Cdh23 and other auditory modifiers.	CDH23 ATP2B2	1.59e-05	2	139	2	23792079
Pubmed	The redox state of the cell regulates the ligand binding affinity of human neuroglobin and cytoglobin.	NGB CYGB	1.59e-05	2	139	2	14530264
Pubmed	A functional study of plasma-membrane calcium-pump isoform 2 mutants causing digenic deafness.	CDH23 ATP2B2	1.59e-05	2	139	2	17234811
Pubmed	Anatomical characterization of cytoglobin and neuroglobin mRNA and protein expression in the mouse brain.	NGB CYGB	1.59e-05	2	139	2	20331985
Pubmed	Suppression of intestinal polyposis in Apc(Min/+) mice by inhibiting nitric oxide production.	APC NOS2	1.59e-05	2	139	2	11731407
Pubmed	A globin in the nucleus!	NGB CYGB	1.59e-05	2	139	2	12796507
Pubmed	Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.	ATP2B2 ATP2B4	1.59e-05	2	139	2	16216224
Pubmed	DCAF8, a novel MuRF1 interaction partner, promotes muscle atrophy.	LINC00518 DCAF8 ZC3HC1 IL18RAP BBX YJU2B ATG4D GPRIN2 BRWD1	1.69e-05	364	139	9	31391242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TNC APC GEMIN5 ZC3HC1 SYNPO SHROOM2 JMY CDKL5 FASN ARVCF PTPRS EIF4B STON2 KBTBD11 SLC17A7 BRSK1 ATP2B2 ATP2B4	1.70e-05	1431	139	18	37142655
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PRUNE2 SHROOM3 DCAF8 SOBP HECTD4 BLNK TRIOBP TNRC6B SYNPO SHROOM2 PCYOX1L BMPR1B PTPRS PHF14 GNAS PARD3 ARHGEF26 PCNT	2.87e-05	1489	139	18	28611215
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	RHBDF1 DHX38 APC GEMIN5 SHROOM2 GPATCH2L KIAA0753 WWC2 EIF4B POP1 ARHGEF3 PARD3 FAM135A PCNT BRWD1	3.08e-05	1084	139	15	11544199
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SHROOM3 RHBDF1 DHX38 PUSL1 APC TRIOBP TNRC6B GEMIN5 ZFC3H1 ORC1 BBX EIF4B POP1 TNRC6A INTS9 PHF14 PARD3 SPEN	3.08e-05	1497	139	18	31527615
Pubmed	Modifier genes and protective alleles in humans and mice.	APC CDH23 ATP2B2	3.37e-05	16	139	3	12787792
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	SHROOM3 CCDC22 APC IRAK1 TNRC6B GRIP1 CCDC88C PROSER3 EIF4B TNRC6A LTBP4 PCNT BRWD1	4.04e-05	853	139	13	28718761
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CHAF1B DCAF8 ABCA12 IRAK1 TNRC6B KSR1 RASAL3 IL21R TNRC6A CRYBG3 PARD3 SRRM2 LTBP4 SENP7 BRWD1	4.29e-05	1116	139	15	31753913
Pubmed	PLK4 deubiquitination by Spata2-CYLD suppresses NEK7-mediated NLRP3 inflammasome activation at the centrosome.	TNRC6B GEMIN5 FASN EIF4B	4.50e-05	49	139	4	31762063
Pubmed	Mammalian Auditory Hair Cell Bundle Stiffness Affects Frequency Tuning by Increasing Coupling along the Length of the Cochlea.	TRIOBP CDH23	4.75e-05	3	139	2	29874579
Pubmed	Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth.	APC FASN	4.75e-05	3	139	2	38732103
Pubmed	CDKL5 ensures excitatory synapse stability by reinforcing NGL-1-PSD95 interaction in the postsynaptic compartment and is impaired in patient iPSC-derived neurons.	CDKL5 SLC17A7	4.75e-05	3	139	2	22922712
Pubmed	Growth differentiation factor-15 promotes glutamate release in medial prefrontal cortex of mice through upregulation of T-type calcium channels.	GDF15 CACNA1I	4.75e-05	3	139	2	27353765
Pubmed	Impaired hypoxic tolerance in APP23 mice: a dysregulation of neuroprotective globin levels.	NGB CYGB	4.75e-05	3	139	2	28391636
Pubmed	Erbin Suppresses KSR1-Mediated RAS/RAF Signaling and Tumorigenesis in Colorectal Cancer.	APC KSR1	4.75e-05	3	139	2	29980571
Pubmed	Cytoglobin is a stress-responsive hemoprotein expressed in the developing and adult brain.	NGB CYGB	4.75e-05	3	139	2	16899760
Pubmed	iRhom1 regulates proteasome activity via PAC1/2 under ER stress.	RHBDF1 PSMG2	4.75e-05	3	139	2	26109405
Pubmed	Expression of TNRC6 (GW182) Proteins Is Not Necessary for Gene Silencing by Fully Complementary RNA Duplexes.	TNRC6B TNRC6A	4.75e-05	3	139	2	31670606
Pubmed	Targeted disruption of the iNOS gene improves adipose tissue inflammation and fibrosis in leptin-deficient ob/ob mice: role of tenascin C.	TNC NOS2	4.75e-05	3	139	2	29449623
Pubmed	ER stress transcription factor Xbp1 suppresses intestinal tumorigenesis and directs intestinal stem cells.	APC XBP1	4.75e-05	3	139	2	24043762
Pubmed	Chronic epithelial NF-κB activation accelerates APC loss and intestinal tumor initiation through iNOS up-regulation.	APC NOS2	4.75e-05	3	139	2	22893683
Pubmed	Impact of scaffolding protein TNRC6 paralogs on gene expression and splicing.	TNRC6B TNRC6A	4.75e-05	3	139	2	34108231
Pubmed	Morphology, GluR1 and GRIP-C localization differ in octopus cells of C57BL6 and B6Cast mice.	CDH23 GRIP1	4.75e-05	3	139	2	12204345
Pubmed	Elevated incidence of polyp formation in APC(Min/⁺)Msh2⁻/⁻ mice is independent of nitric oxide-induced DNA mutations.	APC NOS2	4.75e-05	3	139	2	23741483
Pubmed	The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.	ATP2B2 ATP2B4	4.75e-05	3	139	2	17689535
Pubmed	Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells.	ATP2B2 ATP2B4	4.75e-05	3	139	2	20211863
Pubmed	Gawky is a component of cytoplasmic mRNA processing bodies required for early Drosophila development.	TNRC6B TNRC6A	4.75e-05	3	139	2	16880270
Pubmed	The role of CA-125, GLS and FASN in predicting cytoreduction for epithelial ovarian cancers.	MUC16 FASN	4.75e-05	3	139	2	32698888
Pubmed	Drosophila split ends homologue SHARP functions as a positive regulator of Wnt/beta-catenin/T-cell factor signaling in neoplastic transformation.	APC SPEN	4.75e-05	3	139	2	17234755
Pubmed	Daple coordinates organ-wide and cell-intrinsic polarity to pattern inner-ear hair bundles.	CCDC88C PARD3 PCNT	4.88e-05	18	139	3	29229865
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	APC IRAK1 TNRC6B GEMIN5 FASN TNRC6A CRYBG3 OBI1 PCNT	4.97e-05	418	139	9	34709266
Pubmed	Candidate malaria susceptibility/protective SNPs in hospital and population-based studies: the effect of sub-structuring.	IL17RE GNAS NOS2	5.78e-05	19	139	3	20459687
Pubmed	A quantitative survey of gravity receptor function in mutant mouse strains.	SOBP CDH23 ATP2B2	6.78e-05	20	139	3	16235133
Pubmed	AMP-activated protein kinase phosphorylates retinoblastoma protein to control mammalian brain development.	APC PRKAB1 PARD3	7.88e-05	21	139	3	19217427
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CCDC22 DHX38 TRIOBP KIAA0753 WWC2 MTMR11 ARVCF PTPRS TNRC6A CRYBG3 TRIM36 SRRM2 ATP2B4 PCNT	8.42e-05	1049	139	14	27880917
Pubmed	EMX2-GPR156-Gαi reverses hair cell orientation in mechanosensory epithelia.	CCDC88C PARD3 PCNT	9.10e-05	22	139	3	34001891
Pubmed	Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.	ATP2B2 ATP2B4	9.47e-05	4	139	2	12209837
Pubmed	Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.	ATP2B2 ATP2B4	9.47e-05	4	139	2	12784250
Pubmed	Nitric oxide-mediated regulation of β-amyloid clearance via alterations of MMP-9/TIMP-1.	APC NOS2	9.47e-05	4	139	2	23016931
Pubmed	Replicative verification of susceptibility genes previously identified from families with segregating developmental dysplasia of the hip.	HSPG2 ATP2B4	9.47e-05	4	139	2	34174923
Pubmed	The plasma membrane calcium pump in health and disease.	ATP2B2 ATP2B4	9.47e-05	4	139	2	23413890
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B4	9.47e-05	4	139	2	8245032
Pubmed	Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.	ATP2B2 ATP2B4	9.47e-05	4	139	2	7989379
Pubmed	Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.	ATP2B2 ATP2B4	9.47e-05	4	139	2	11152753
Pubmed	High-fructose corn syrup enhances intestinal tumor growth in mice.	APC FASN	9.47e-05	4	139	2	30898933
Pubmed	Two PABPC1-binding sites in GW182 proteins promote miRNA-mediated gene silencing.	TNRC6B TNRC6A	9.47e-05	4	139	2	21063388
Pubmed	PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.	ATP2B2 ATP2B4	9.47e-05	4	139	2	36130203
Pubmed	Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.	ATP2B2 ATP2B4	9.47e-05	4	139	2	10434059
Pubmed	Transcription factor PROX1 induces colon cancer progression by promoting the transition from benign to highly dysplastic phenotype.	APC LTBP4	9.47e-05	4	139	2	18455124
Pubmed	A reciprocal relationship exists between non-steroidal anti-inflammatory drug-activated gene-1 (NAG-1) and cyclooxygenase-2.	GDF15 APC	9.47e-05	4	139	2	19375854
Pubmed	Differential expression pattern of protein ARVCF in nephron segments of human and mouse kidney.	SYNPO ARVCF	9.47e-05	4	139	2	18600340
Pubmed	Calcium pumps of plasma membrane and cell interior.	ATP2B2 ATP2B4	9.47e-05	4	139	2	15101689
Pubmed	Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.	ATP2B2 ATP2B4	9.47e-05	4	139	2	10577388
Pubmed	Structural organization, ion transport, and energy transduction of P-type ATPases.	ATP2B2 ATP2B4	9.47e-05	4	139	2	8634322
Interaction	CEP135 interactions	SHROOM3 CCDC22 APC TNRC6B KIAA0753 RUSC2 GRIP1 CCDC88C PROSER3 TNRC6A TRIM36 PCNT	3.86e-07	272	138	12	int:CEP135
Interaction	LATS1 interactions	TNC APC TNRC6B ARMCX1 KIAA0753 CCDC88C WWC2 EIF4B TNRC6A RACGAP1 PARD3 SRRM2 PCNT MYBPC2	2.04e-06	440	138	14	int:LATS1
Interaction	YWHAE interactions	CHAF1B SHROOM3 NGB EXPH5 USP43 APC ZC3HC1 MMP20 SHROOM2 RUSC2 GRIP1 CCDC88C KSR1 WWC2 RASAL3 EIF4B RACGAP1 BRSK1 PARD3 SRRM2 NOS2 ATP2B4 GPRIN2	1.41e-05	1256	138	23	int:YWHAE
Interaction	SFN interactions	SHROOM3 EXPH5 APC RUSC2 GRIP1 CCDC88C KSR1 WWC2 RHPN2 EIF4B RACGAP1 CRYBG3 PARD3 SRRM2 OBI1 GPRIN2	2.15e-05	692	138	16	int:SFN
Interaction	YWHAG interactions	SHROOM3 NGB EXPH5 HECTD4 USP43 APC SYNPO SHROOM2 EML3 KIAA0753 RUSC2 GRIP1 CCDC88C KSR1 WWC2 RHPN2 EIF4B RACGAP1 GNAS PARD3 SRRM2 NOS2	3.96e-05	1248	138	22	int:YWHAG
Interaction	MPHOSPH9 interactions	TNRC6B KIAA0753 TNRC6A TRIM36 OBI1 PCNT	4.87e-05	95	138	6	int:MPHOSPH9
GeneFamily	Fibronectin type III domain containing	ROBO4 TNC INSRR PTPRS TRIM36 MYBPC2	1.66e-04	160	92	6	555
GeneFamily	ATPases Ca2+ transporting	ATP2B2 ATP2B4	9.01e-04	9	92	2	1209
GeneFamily	PDZ domain containing	SHROOM3 SHROOM2 GRIP1 RHPN2 PARD3	1.07e-03	152	92	5	1220
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL18RAP IL17RE IL21R	1.27e-03	42	92	3	602
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	APC ARMCX1 ARVCF	1.36e-03	43	92	3	409
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	ROBO4 HSPG2 PTPRS MDGA1 MYBPC2	1.39e-03	161	92	5	593
GeneFamily	WD repeat domain containing	CHAF1B DCAF8 DCAF8L2 GEMIN5 EML3 BRWD1	2.20e-03	262	92	6	362
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	ZC3HC1 ZFC3H1	2.58e-03	15	92	2	26
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	DCAF8 BRWD1	3.72e-03	18	92	2	498
GeneFamily	ADAM metallopeptidases with thrombospondin type 1 motif	ADAMTS9 ADAMTS17	4.14e-03	19	92	2	50
ToppCell	droplet-Lung-21m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 HSPG2 SYNPO RHPN2 LTBP4 ATP2B2 FAM135A ATP2B4	1.30e-07	186	139	8	c116cc9f41971622264434ebe29d18e719b0ae19
ToppCell	5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	RHBDF1 TNC ZNF268 USP43 PARP14 SHROOM2 ORC1 RACGAP1	1.36e-07	187	139	8	a6a112689d1c9049f57935ad9d2f4955538427de
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 SHROOM3 SYNPO WWC2 IL17RE MDGA1 ARHGEF26 GPRIN2	1.87e-07	195	139	8	07a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCell	356C-Epithelial_cells-Epithelial-I_(AT1)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 SHROOM3 SYNPO WWC2 IL17RE MDGA1 ARHGEF26 GPRIN2	1.87e-07	195	139	8	b65511770ed67f7447847e2187555b362988af45
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 USP43 SHROOM2 C4orf54 GRIP1 CCDC88C BMPR1B	6.67e-07	158	139	7	debebc8534a80e5500051f6fd352dc201585968d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 USP43 LRRC9 GRIP1 BMPR1B RACGAP1 CRYBG3	1.05e-06	169	139	7	a4fd646b9bf87225131fca530bd6b52df9eaf489
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KHDRBS2 MUC16 GRIP1 BMPR1B RHPN2 IL17RE NEIL3	1.37e-06	176	139	7	8e7f38de8bf68077e2138f4d06c1f55b0fd096cc
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KHDRBS2 MUC16 GRIP1 BMPR1B RHPN2 IL17RE NEIL3	1.37e-06	176	139	7	ed575330a08a6748ea4b28433292c8cfd157d444
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYGB MUC16 GRIP1 ARHGAP22 IL17RE MAPK4 ARMH4	1.66e-06	181	139	7	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CYGB MUC16 GRIP1 ARHGAP22 IL17RE MAPK4 ARMH4	1.66e-06	181	139	7	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	COVID-19-lung-AT1\|lung / Disease (COVID-19 only), tissue and cell type	SHROOM3 EXPH5 KHDRBS2 GRIP1 WWC2 MAPK4 ARHGEF26	1.78e-06	183	139	7	942530449e9c6583705eeb8f6f12621daea57252
ToppCell	AT1-AT2_cells-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	KHDRBS2 SYNPO CDKL5 WWC2 IL17RE MAPK4 ARHGEF26	1.78e-06	183	139	7	6821dca076318115d360ff426eb1218cfe104063
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D175\|Adult / Lineage, Cell type, age group and donor	SHROOM3 KHDRBS2 WWC2 BMPR1B MAPK4 ARHGEF26 GPRIN2	1.92e-06	185	139	7	32b4e68e551d435a732f253f6ad83408c759a642
ToppCell	Control-Epithelial-ATI\|World / Disease state, Lineage and Cell class	SHROOM3 KHDRBS2 SYNPO WWC2 PARD3 ARHGEF26 GPRIN2	1.92e-06	185	139	7	0563d5042bb96ecce8446fbf26d05ef7a45e23c5
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 SYNPO RHPN2 LTBP4 ATP2B2 FAM135A ATP2B4	1.99e-06	186	139	7	ffbc78058be8f0dc2e0335cc4c3195a636d17721
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 SYNPO RHPN2 LTBP4 ATP2B2 FAM135A ATP2B4	1.99e-06	186	139	7	ed924852cd7132c8f6703522037dc22bd2c83193
ToppCell	droplet-Lung-1m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HSPG2 SYNPO RHPN2 LTBP4 ATP2B2 FAM135A ATP2B4	2.29e-06	190	139	7	3b9abc25b17e7295356ded57ff2ca519fa9f2686
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GDF15 EXPH5 KHDRBS2 BLNK USP43 GRIP1 BMPR1B	2.54e-06	193	139	7	b38aaffbea36ef6c08ebe82675438f873c89b242
ToppCell	(7)_Epithelial-I_(AT1)\|World / Lung cell shreds - cell class (v4) and cell subclass (v4)	SHROOM3 SYNPO WWC2 IL17RE MDGA1 ARHGEF26 GPRIN2	2.81e-06	196	139	7	150554fa06868d29b0608189862eef6505ba757f
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MATK IL18RAP CCDC88C RASAL3 GAB3 LTBP4 ATP2B4	2.81e-06	196	139	7	60f5deb97f3d6f8422bb5849778205a7022002ae
ToppCell	AT1-AT2_cells\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 SHROOM3 EXPH5 SYNPO WWC2 ARHGEF26 GPRIN2	3.00e-06	198	139	7	a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNC SYNPO ADAMTS9 TMEM132A MAPK4 ARHGEF26 LTBP4	3.00e-06	198	139	7	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	PCW_10-12-Epithelial-Epithelial_airway\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SHROOM3 GDF15 EXPH5 KHDRBS2 BLNK GRIP1 BMPR1B	3.00e-06	198	139	7	9a12e5e47236433e512c668005fe3f8be6fde95c
ToppCell	(7)_Epithelial_cells-(7)_Epithelial-I_(AT1)\|(7)_Epithelial_cells / Lung cell shreds - cell class (v4) and cell subclass (v4)	HSPG2 KHDRBS2 SYNPO WWC2 IL17RE MDGA1 ARHGEF26	3.10e-06	199	139	7	5a002d49a8b84c158f7b4d7a3e78e6a937757bb7
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Rrad\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SHROOM3 NGB SYNPO MAPK4 MDGA1 ATP2B4	4.80e-06	138	139	6	b3a040c5d0e1cc94d9b19155bca8700edba2d243
ToppCell	VE-CD8-memory_CD4\|VE / Condition, Cell_class and T cell subcluster	MATK USP43 CCDC88C FASN GAB3 SLC17A7	8.35e-06	152	139	6	9401b7770c1bdc87eba25e82922f5dd1c4fa37ee
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 ABCA12 GRIP1 BMPR1B SIGLEC10 ARHGEF3	8.67e-06	153	139	6	9b6675ace8a83c8d446b722301d0ec4e6840f3fc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 ABCA12 BLNK GRIP1 BMPR1B SIGLEC10	1.00e-05	157	139	6	2c5295043611bac7dfa4aef2146681bce4a33a8f
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	NGB EXPH5 SYNPO MAPK4 MDGA1 ATP2B4	1.16e-05	161	139	6	e3327c296d48e821004e61a573abb75624a6f040
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ZDHHC21 SHROOM3 GDF15 GRIP1 BMPR1B IL17RE	1.20e-05	162	139	6	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 USP43 LRRC9 GRIP1 BMPR1B RACGAP1	1.53e-05	169	139	6	4b3a7b4a497178799b6b2f0b744f5fb752cee31a
ToppCell	PND28-Immune-Immune_Myeloid-DC-cDC2-cDC2_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CHAF1B HECTD4 IL18RAP PCYOX1L RACGAP1 NEIL3	1.69e-05	172	139	6	eba1568d4307e91c94fc616549057cbed8df5840
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-Hepatocyte_(Pericentral)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 SHROOM2 ARMCX1 YJU2B PLXNC1 ATP2B4	1.86e-05	175	139	6	98dc3b6f69a29d587f503898f09912700950e3d9
ToppCell	AT1_cells-HP_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 SYNPO MAPK4 MDGA1 ARHGEF26 GPRIN2	1.92e-05	176	139	6	458720776b0151cd55acc352d509599cb62f0ca8
ToppCell	facs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PRUNE2 HSPG2 SYNPO LTBP4 ATP2B2 ATP2B4	1.98e-05	177	139	6	d68132e145bd413404fdbe215b5dbe520e756e50
ToppCell	COVID-19-Epithelial_cells-AT1\|COVID-19 / group, cell type (main and fine annotations)	SHROOM3 EXPH5 KHDRBS2 WWC2 PARD3 ARHGEF26	2.11e-05	179	139	6	a0b33bd69ffdfd5d38d80207fb40058a490aa19e
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 GDF15 KHDRBS2 WWC2 PARD3 ARHGEF26	2.11e-05	179	139	6	cb38b54261a7af5ee3347e64c8aa880a77ed0763
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 KHDRBS2 WWC2 IL17RE MAPK4 ARHGEF26	2.11e-05	179	139	6	4f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCell	5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SHROOM3 KHDRBS2 MDGA1 ARHGEF26 FAM135A GPRIN2	2.11e-05	179	139	6	d5e3e7f1cd8f683f39a7416f12af7e766dcbead8
ToppCell	AT1_cells-Cryobiopsy_01\|World / lung cells shred on cell class, cell subclass, sample id	HSPG2 KHDRBS2 SYNPO MDGA1 ARHGEF26 GPRIN2	2.11e-05	179	139	6	1603117b52623663458a977c94bf7f9f6c1114b8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 EXPH5 CYGB SLC17A7 MDGA1 ATP2B2	2.18e-05	180	139	6	d76349ecef7c5878bf215e946f032264161eb61b
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PCARE SYNPO ARHGEF3 ARHGEF26 ARMH4	2.18e-05	180	139	6	d685fa2b013bc085dbef7c40956ed3043f83e483
ToppCell	COVID-19-lung-AT1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SHROOM3 EXPH5 KHDRBS2 WWC2 IL17RE ARHGEF26	2.39e-05	183	139	6	7b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCell	droplet-Kidney-nan-21m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 TNC CYGB ARMCX1 RUSC2 ARHGAP22	2.39e-05	183	139	6	ad7421623e4c0c5ba02eec56e9bdae43ebb88d90
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 SYNPO WWC2 IL17RE MDGA1 ARHGEF26	2.47e-05	184	139	6	c7073d1b2c4fdb154d87678b92a0629c02116972
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHROOM3 KHDRBS2 CDKL5 WWC2 IL17RE ARHGEF26	2.47e-05	184	139	6	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	343B-Epithelial_cells-Epithelial-I_(AT1)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	HSPG2 SYNPO WWC2 IL17RE MDGA1 ARHGEF26	2.47e-05	184	139	6	1ed558a88215b248431c524ea16f13d9022ae98c
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYGB SLC17A7 CACNA1I FGF14 MDGA1 ATP2B2	2.54e-05	185	139	6	70de48988c1f8e0809afc8092b663aa439d8e528
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	PCARE SYNPO ARHGEF3 ARHGEF26 LTBP4 ARMH4	2.62e-05	186	139	6	1094c7140131454b2583200e1c01e81ccab3db23
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPG2 SYNPO RHPN2 LTBP4 ATP2B2 FAM135A	2.62e-05	186	139	6	1e67bfb248366d7395efdd2d5e70a97bdb2e68af
ToppCell	COPD-Epithelial-ATI\|COPD / Disease state, Lineage and Cell class	HSPG2 SHROOM3 KHDRBS2 PARD3 ARHGEF26 GPRIN2	2.62e-05	186	139	6	df0977f6f48a2d4e11b59971f098b01204242f0f
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE-Gja1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TNC RFX4 LRRC9 BMPR1B STON2	2.69e-05	112	139	5	e30cd0b7b755c63081bbeed4e1a884b6640d34f8
ToppCell	Posterior_cortex-Macroglia-ASTROCYTE\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	TNC RFX4 LRRC9 BMPR1B STON2	2.69e-05	112	139	5	1c0bcc6c972c50a9d950cd56b65efb8d778ec25a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CYGB SLC17A7 CACNA1I FGF14 MDGA1 ATP2B2	2.70e-05	187	139	6	7b2cd0c618ed081223343f3bec2244c8723c9a31
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PCARE SYNPO ARHGEF3 ARHGEF26 ARMH4	2.70e-05	187	139	6	24c2a3962da364e46e98abeab5f8234376fa26bb
ToppCell	Control-Epithelial-ATI\|Epithelial / Disease state, Lineage and Cell class	KHDRBS2 SYNPO WWC2 IL17RE ARHGEF26 GPRIN2	2.70e-05	187	139	6	3a032432f780525f4f4c2a358897d9989b1ecae7
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HSPG2 SHROOM3 GDF15 KHDRBS2 WWC2 ARHGEF26	2.78e-05	188	139	6	eea652bab161f19148a883e7e3fe2523b36b3cea
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GDF15 EXPH5 KHDRBS2 BLNK GRIP1 IL17RE	2.78e-05	188	139	6	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	GDF15 EXPH5 KHDRBS2 BLNK GRIP1 IL17RE	2.78e-05	188	139	6	beb2df2332a46cc81b10e8e29fc9829020111f03
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PCARE SYNPO ARHGEF26 LTBP4 ARMH4	2.78e-05	188	139	6	047c4e0b03fc8334e38c48977e41d26dbe229d47
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	SHROOM3 KHDRBS2 BMPR1B IL17RE PARD3 ARHGEF26	2.87e-05	189	139	6	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SHROOM3 KHDRBS2 WWC2 MAPK4 PARD3 ARHGEF26	2.95e-05	190	139	6	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	PCW_13-14-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GDF15 EXPH5 KHDRBS2 BLNK GRIP1 BMPR1B	3.04e-05	191	139	6	63aa671837b79d2feb7ed1e67712cc01caf72bef
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Degenerative_Podocyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PCARE SYNPO ARHGEF3 ARHGEF26 ARMH4	3.13e-05	192	139	6	ef0aba777072429a6ab7dcfcc305673975946580
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SHROOM3 GDF15 EXPH5 BLNK GRIP1 BMPR1B	3.22e-05	193	139	6	b25cdca3a1e381784ae48ca73c51cbb6ac62b811
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	EXPH5 PCARE SYNPO ARHGEF3 ARHGEF26 ARMH4	3.22e-05	193	139	6	3eaa0461618582a1754400624350d269d24e750a
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MATK IL18RAP CCDC88C RASAL3 IL21R ARHGEF3	3.22e-05	193	139	6	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 BLNK GRIP1 BMPR1B ADAMTS9 FAM135A	3.32e-05	194	139	6	46070fbb0ee0eb9e1801c43b73a15707471056dc
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	SHROOM3 BLNK GRIP1 BMPR1B ADAMTS9 FAM135A	3.32e-05	194	139	6	abacb6a8d7a9003f2f6c2be0305507f1c1c50347
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SHROOM3 GRIP1 RHPN2 PARD3 FAM135A	3.32e-05	194	139	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	10x5'v1-week_17-19-Endothelial\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ROBO4 HSPG2 SYNPO LRRC9 ADAMTS9 NOS2	3.32e-05	194	139	6	e141beafc9252e5d8c949252bfab53e127c881dc
ToppCell	PCW_13-14-Epithelial-Epithelial_airway\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	GDF15 EXPH5 KHDRBS2 BLNK GRIP1 BMPR1B	3.32e-05	194	139	6	7b2b40a56eb9c7203ca50133b2da4fd8fdd4a5cf
ToppCell	10x5'v1-week_17-19-Endothelial-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ROBO4 HSPG2 SYNPO LRRC9 ADAMTS9 NOS2	3.32e-05	194	139	6	953578102ffc7b612ee8fce45e414750800fef5d
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 HSPG2 ARMCX1 PLXNC1 LTBP4 ATP2B4	3.42e-05	195	139	6	f55ab1018a6cde7d517b53e6ce44c3f7bde485c4
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 HSPG2 ARMCX1 PLXNC1 LTBP4 ATP2B4	3.42e-05	195	139	6	ea1b00805391dca8be0883b635768b296369919a
ToppCell	10x5'v1-week_17-19-Endothelial-stroma-sinusoidal_EC\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	ROBO4 HSPG2 RSPH4A LRRC9 ADAMTS9 NOS2	3.42e-05	195	139	6	22a481927147ec4ae9d59e6af7c87df0e9cb51e4
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SHROOM3 GDF15 EXPH5 KHDRBS2 GRIP1 BMPR1B	3.42e-05	195	139	6	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	droplet-Liver-LIVER-NPC-1m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 HSPG2 ARMCX1 PLXNC1 LTBP4 ATP2B4	3.42e-05	195	139	6	126f46dd15dddcf5701144718bb8ba1ce84b2d1d
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1\|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MATK CCDC88C RASAL3 GAB3 ARHGEF3 ATP2B4	3.42e-05	195	139	6	14a6466524c22920daa622fbc710daf1defb46c3
ToppCell	Bronchial-10x5prime-Immune_Lymphocytic-NK-ILC-T_NK-ILC\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MORC1 MATK IL18RAP RASAL3 IL21R ADAMTS17	3.52e-05	196	139	6	1cc2b11764584129703ec61965e8ec4e051464e7
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 HSPG2 ARMCX1 PLXNC1 LTBP4 ATP2B4	3.62e-05	197	139	6	d584d0334ea97e3fa8c4cd869f5eeea2c7a1ed04
ToppCell	Parenchymal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HSPG2 ADAMTS9 TMEM132A LTBP4 ATP2B2 MYBPC2	3.62e-05	197	139	6	ad4a3b5da2190be9495382a2952991e1de9f190d
ToppCell	facs-Liver-Liver_non-hepato/SCs-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ROBO4 HSPG2 ARMCX1 PLXNC1 LTBP4 ATP2B4	3.62e-05	197	139	6	412091994196a06c2779b4c2cfed84be889a5f8d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MATK IL18RAP CCDC88C RASAL3 GAB3 ATP2B4	3.72e-05	198	139	6	a6b942fe850e287e1cb705684e29218072daf891
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	HSPG2 EXPH5 GRIP1 CDKL5 WWC2 ARHGEF26	3.72e-05	198	139	6	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ABCA12 TNC GDF15 KSR1 BMPR1B NOS2	3.72e-05	198	139	6	19d8ff3a4f911b13ecc34844202925475ad4d2ab
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_alveolar-AT1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 KHDRBS2 WWC2 IL17RE ARHGEF26 GPRIN2	3.83e-05	199	139	6	aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ROBO4 HSPG2 SYNPO CCDC88C ADAMTS9 CRYBG3	3.83e-05	199	139	6	b15304d3d3f6c254969b54a61bee3d9f368840b2
ToppCell	Tracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SIGLEC9 BLNK ARHGAP22 PLXNC1 SIGLEC10 GAB3	3.83e-05	199	139	6	744b63fba33b176ab7dde11646ccb313665505f7
ToppCell	Macroglial-Astrocytes\|Macroglial / cells hierarchy compared to all cells using T-Statistic	SHROOM3 BMPR1B STON2 MAPK4 PARD3 ARHGEF26	3.93e-05	200	139	6	941536b7c32f1e63c70535233b2ccce0cd7bf96e
ToppCell	Tracheal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 XBP1 MUC16 GRIP1 RHPN2 ARHGEF3	3.93e-05	200	139	6	d3af0a706baf66e3f32e67b17dcfc31e5b32ce0e
ToppCell	Biopsy_Control_(H.)-Epithelial-AT1\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	HSPG2 KHDRBS2 WWC2 IL17RE ARHGEF26 GPRIN2	3.93e-05	200	139	6	3a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCell	Tracheal-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SHROOM3 XBP1 MUC16 GRIP1 RHPN2 ADAMTS17	3.93e-05	200	139	6	0eb9ad8c0373bcc62029ec21c590ed03aaacd039
ToppCell	droplet-Heart-HEART-1m-Hematologic-nan\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BLNK ARHGAP22 STON2 KBTBD11 TRIM36	4.92e-05	127	139	5	983489a69d3b1f1fe21110a862ac1dba53e9d31c
ToppCell	E18.5-samps-Mesenchymal-Matrix_fibroblast-matrix_-_mature_2\|E18.5-samps / Age Group, Lineage, Cell class and subclass	MATK KSR1 FGF14 MAPK4 ARMH4	5.70e-05	131	139	5	f2eee150f5cff852e8f52f09b35e26f17d80833b
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZNF268 C4orf54 GRIP1 BMPR1B SIGLEC10	9.84e-05	147	139	5	b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Dpy19l1_(Neuron.Gad1Gad2.Cplx3-Dpy19l1)\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MORC1 CDH23 GPATCH2L ORC1	9.91e-05	77	139	4	4a0a2f1a021790ff598a8655811eac1c367316b3
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Cplx3-Inhibitory_Neuron.Gad1Gad2.Cplx3-Dpy19l1_(Neuron.Gad1Gad2.Cplx3-Dpy19l1)-\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MORC1 CDH23 GPATCH2L ORC1	9.91e-05	77	139	4	459fe29a53b88af77a4ced7b11fa1d0a17fec8e5
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MATK INSRR IL18RAP RASAL3 CACNA1I	1.05e-04	149	139	5	f4bee5fdaaa4a1917e403de90e5a62353006df24
ToppCell	PBMC-Severe-cDC_1\|Severe / Compartment, Disease Groups and Clusters	SYNPO PLXNC1 TMEM132A NEIL3	1.21e-04	81	139	4	6d1e524f000b71c935359afc801a1d31f218fec8
Disease	Antihypertensive use measurement	HSPG2 XBP1 ARVCF TNRC6A ARHGEF3 MAPK4 TRIM36 ATP2B2 ATP2B4	4.12e-06	265	136	9	EFO_0009927
Disease	Deafness, Autosomal Recessive 12	CDH23 ATP2B2	2.11e-05	2	136	2	C1832394
Disease	Autosomal recessive nonsyndromic hearing loss 12	CDH23 ATP2B2	2.11e-05	2	136	2	cv:C1832394
Disease	autosomal recessive nonsyndromic deafness 12 (is_implicated_in)	CDH23 ATP2B2	2.11e-05	2	136	2	DOID:0110467 (is_implicated_in)
Disease	DEAFNESS, AUTOSOMAL RECESSIVE 12	CDH23 ATP2B2	2.11e-05	2	136	2	601386
Disease	amp kinase (alpha2beta2gamma1) measurement	PRKAB1 ARHGEF3	2.11e-05	2	136	2	EFO_0020143
Disease	Heredodegenerative Disorders, Nervous System	NGB CYGB	6.31e-05	3	136	2	C0751870
Disease	serine/threonine-protein kinase BRSK2 measurement	ARHGEF3 BRSK1	6.31e-05	3	136	2	EFO_0803063
Disease	Gastrointestinal Neoplasms	GDF15 APC	1.26e-04	4	136	2	C0017185
Disease	Malignant neoplasm of gastrointestinal tract	GDF15 APC	1.26e-04	4	136	2	C0685938
Disease	KDEL motif-containing protein 2 measurement	EXPH5 ARHGEF3	1.26e-04	4	136	2	EFO_0801740
Disease	Dwarfism	RSPH4A TG ORC1	2.04e-04	25	136	3	C0013336
Disease	Anoxic-Ischemic Encephalopathy	IRAK1 NOS2	2.09e-04	5	136	2	C0752305
Disease	Hypoxic-Ischemic Encephalopathy	IRAK1 NOS2	2.09e-04	5	136	2	C0752304
Disease	Anoxia-Ischemia, Cerebral	IRAK1 NOS2	2.09e-04	5	136	2	C0752307
Disease	Anoxia-Ischemia, Brain	IRAK1 NOS2	2.09e-04	5	136	2	C0752306
Disease	Hypoxia-Ischemia, Brain	IRAK1 NOS2	2.09e-04	5	136	2	C0752308
Disease	Cerebral Hypoxia-Ischemia	IRAK1 NOS2	2.09e-04	5	136	2	C0178540
Disease	splicing factor 3B subunit 4 measurement	MTMR11 ARHGEF3	2.09e-04	5	136	2	EFO_0803100
Disease	Coronary Arteriosclerosis	GDF15 HECTD4 IRAK1 ZC3HC1	2.35e-04	65	136	4	C0010054
Disease	Coronary Artery Disease	GDF15 HECTD4 IRAK1 ZC3HC1	2.35e-04	65	136	4	C1956346
Disease	severe acute respiratory syndrome, COVID-19	GDF15 DCAF8L2 TG GRIP1 KSR1 ADAMTS17 PHF14 ARHGEF3 PARD3	2.38e-04	447	136	9	EFO_0000694, MONDO_0100096
Disease	Hailey-Hailey disease (implicated_via_orthology)	ATP2B2 ATP2B4	3.13e-04	6	136	2	DOID:0050429 (implicated_via_orthology)
Disease	FEV/FEC ratio	HSPG2 CHAF1B DCAF8 KHDRBS2 CDH23 GPATCH2L LINC00310 TG BTBD16 WWC2 MTMR11 ARVCF PARD3 ARHGEF26 LTBP4	5.57e-04	1228	136	15	EFO_0004713
Disease	age at initiation of corrective lens use	RFX4 BRWD1	5.80e-04	8	136	2	EFO_0021781
Disease	Hepatic Insufficiency	CYGB NOS2	7.43e-04	9	136	2	C1306571
Disease	Uterine leiomyoma, estrogen-receptor negative breast cancer	EXPH5 TNRC6B	9.26e-04	10	136	2	EFO_1000650, HP_0000131
Disease	brain measurement, neuroimaging measurement	TRIOBP RFX4 TG CCDC88C RHPN2 ADAMTS9 TNRC6A FGF14 PARD3	1.05e-03	550	136	9	EFO_0004346, EFO_0004464
Disease	Endogenous depression	PDCD2 TG GNAS	1.26e-03	46	136	3	C0011573
Disease	Mouth Diseases	CHAF1B GDF15	1.35e-03	12	136	2	C0026636
Disease	DEAFNESS, AUTOSOMAL RECESSIVE (disorder)	TRIOBP CDH23	1.59e-03	13	136	2	C1846647
Disease	waist-hip ratio	PRUNE2 ZNF268 HECTD4 XBP1 TNRC6B RFX4 LINC00310 BMPR1B BBX ADAMTS9 PTPRS TNRC6A ARHGEF26 ATP2B4	1.62e-03	1226	136	14	EFO_0004343
Disease	Nonsyndromic Hearing Loss and Deafness, Autosomal Recessive	TRIOBP CDH23 ATP2B2	1.70e-03	51	136	3	cv:CN043650
Disease	Glioblastoma Multiforme	INSRR APC IRAK1 LTBP4	1.77e-03	111	136	4	C1621958
Disease	extrinsic allergic alveolitis (is_marker_for)	TNC NOS2	1.85e-03	14	136	2	DOID:841 (is_marker_for)
Disease	macula measurement	CHAF1B ARHGAP22 RHPN2 ADAMTS9 TNRC6A	1.87e-03	189	136	5	EFO_0008375
Disease	conotruncal heart malformations	NGB PRDM9 PLXNC1 MDGA1	1.95e-03	114	136	4	MONDO_0016581
Disease	cortical thickness	HSPG2 SHROOM3 TRIOBP TNRC6B ZC3HC1 RFX4 TG GRIP1 ADAMTS9 PLXNC1 TNRC6A PARD3 TRIM36	1.95e-03	1113	136	13	EFO_0004840
Disease	Metastatic melanoma	CDKL5 BMPR1B BRSK1	2.00e-03	54	136	3	C0278883
Disease	Liver carcinoma	CHAF1B GDF15 APC ORC1 FASN KBTBD11 RACGAP1 NEIL3	2.49e-03	507	136	8	C2239176
Disease	Eye Abnormalities	APC BMPR1B	2.74e-03	17	136	2	C0015393
Disease	prostate carcinoma	SHROOM3 TNC EXPH5 TNRC6B MMP20 SHROOM2 LINC00310 CCDC88C BBX DEDD2 SPEN	2.85e-03	891	136	11	EFO_0001663
Disease	coronary artery disease, plasminogen activator inhibitor 1 measurement	ZC3HC1 LINC00310 ARHGEF26	3.11e-03	63	136	3	EFO_0001645, EFO_0004792
Disease	pulmonary hypertension (is_marker_for)	TNC BMPR1B NOS2	3.25e-03	64	136	3	DOID:6432 (is_marker_for)
Disease	bitter alcoholic beverage consumption measurement	TNRC6B TNRC6A SENP7 ARMH4	3.40e-03	133	136	4	EFO_0010092
Disease	osteochondrodysplasia (is_implicated_in)	HSPG2 BMPR1B	3.43e-03	19	136	2	DOID:2256 (is_implicated_in)
Disease	Chronic myeloproliferative disorder	ORC1 PCNT	3.43e-03	19	136	2	C1292778
Disease	polycystic kidney disease (biomarker_via_orthology)	TNC GNAS	3.43e-03	19	136	2	DOID:0080322 (biomarker_via_orthology)
Disease	Profound Mental Retardation	APC RABL6 FASN GNAS	3.98e-03	139	136	4	C0020796
Disease	Mental Retardation, Psychosocial	APC RABL6 FASN GNAS	3.98e-03	139	136	4	C0025363
Disease	Mental deficiency	APC RABL6 FASN GNAS	3.98e-03	139	136	4	C0917816
Disease	tissue plasminogen activator measurement, coronary artery disease	ZC3HC1 LINC00310 ARHGEF26	4.35e-03	71	136	3	EFO_0001645, EFO_0004791
Disease	Seckel syndrome	ORC1 PCNT	4.59e-03	22	136	2	C0265202
Disease	cholangiocarcinoma (is_implicated_in)	APC GNAS	4.59e-03	22	136	2	DOID:4947 (is_implicated_in)
Disease	renal system measurement, blood urea nitrogen measurement	HECTD4 GNAS	4.59e-03	22	136	2	EFO_0004741, EFO_0004742
Disease	progranulin measurement	CDH23 GRIP1	4.59e-03	22	136	2	EFO_0004625

Protein segments in the cluster

Peptide	Gene	Start	Entry
RSKDASPINRWSPTR	PRPF4B	426	Q13523
WSRISRSPSTKAPSI	NT5C1B	121	Q96P26
KNHSSPSERSWRSPS	C2orf16	1596	Q68DN1
STWTAPQSRLTARPS	GNAS	261	P84996
SQKIRWSRSPPSSLL	LINC00310	11	P59036
PWSRNAAPSSTKRRD	ARHGEF3	86	Q9NR81
RRSPSVDSARKEPRW	ARVCF	341	O00192
PRKKLWAFPSDSSRD	BBX	166	Q8WY36
TEDRRTLVLNFKWPP	CRYBG3	1466	Q68DQ2
TGSTNRWRLPKQPFS	BTBD16	16	Q32M84
TAQTTRSLRTKIWAP	ABCA12	991	Q86UK0
TQLSRRWEPLATTIS	ARMH4	511	Q86TY3
AWSKTTPRRINLTPL	CHAF1B	491	Q13112
PRSLWQKSASSLPAS	LINC00518	86	Q8N0U6
SNSITPLWRRRSIPQ	ARHGEF26	11	Q96DR7
QWETGSPPTKRQRRS	DEDD2	146	Q8WXF8
ALQRSSPVWVPESRR	DNHD1	4416	Q96M86
PATSRRPEQVTWAAQ	CCDC22	316	O60826
IKKLRPSFPNRWSSD	BMPR1B	446	O00238
FIVKASSNRSWTPPR	CDH23	2801	Q9H251
IWPKLRVLARSSPTD	ATP2B2	781	Q01814
IWPKLRVLARSSPTD	ATP2B4	746	P23634
RRKWSLTPSPSAEAQ	ADAMTS17	181	Q8TE56
RPWTRDSASLPRKPS	RASAL3	851	Q86YV0
WTRISSTPAKLEQRT	HSPG2	3146	P98160
TKWSSIPASKPRRGT	RABL6	496	Q3YEC7
RASKPHSTPATLQWL	RFX4	51	Q33E94
PSPLKDAVEVSTWRR	INTS9	166	Q9NV88
STKEERPRILSIWPS	LRRC9	851	Q6ZRR7
RSSSLPSWKSLLNVP	MORC1	766	Q86VD1
PRPQVRWTKTAGSAS	MDGA1	66	Q8NFP4
ATPLSSPRHVRIKNW	NOS2	76	P35228
TEPTARRKSSPETWA	MUC16	3131	Q8WXI7
RSTVRNSPWKTPETT	MUC16	3221	Q8WXI7
TVTWRGLKSVPPNSR	IL18RAP	536	O95256
LDSSRLPVKWTAPEA	MATK	381	P42679
ATLVRSPGPRRSSAW	JMY	96	Q8N9B5
KLPTRNTIISWTSSR	NEIL3	291	Q8TAT5
AVSSRWLPRPAISSE	MTMR11	586	A4FU01
PSFVSSTWEVKRPLR	MAPK4	261	P31152
EVPSSRPQAALIWSR	GAB3	246	Q8WWW8
RSKRTQPSDPETWES	IL17RE	151	Q8NFR9
SSETSALPRPRWQVV	DCAF8L2	176	P0C7V8
GSRERLKSTVDSPPW	CCDC88C	1421	Q9P219
SFPRPVKTTWLNRNA	FAM135A	181	Q9P2D6
AAVWRVQSPKPLFRT	PCYOX1L	391	Q8NBM8
SAPAWRLRSEQFPSK	PDCD2	16	Q16342
SIWSLPNSRAPFAIK	PLXNC1	1371	O60486
RPWRGPISRKASQTS	KSR1	586	Q8IVT5
SSETSALPRPRWQAL	DCAF8	141	Q5TAQ9
WDRPSASRRRSSPSK	FGF14	21	Q92915
LQSPWSTSFVPEKRN	OBI1	686	Q5W0B1
QSPKRTPLSSIIWNR	EXPH5	361	Q8NEV8
RLSPTASRSWDVTRP	GDF15	126	Q99988
QADRRQPKEITWSPS	HECTD4	1931	Q9Y4D8
EAEAWSPRKLPSSAS	IRAK1	126	P51617
GNPSRARSWLSPRVS	MMACHC	261	Q9Y4U1
SAWKPDETAPQSSLR	PCNT	3096	O95613
ARSTRPQAWVPREKL	PHF14	551	O94880
RSETSITLSWSPPRQ	PTPRS	536	Q13332
RTSELWKRNGPSSSP	POM121B	6	A6NF01
RTWQREISRAFSSPP	PRDM9	466	Q9NQV7
IWKSQRTPGDPSESR	POP1	311	Q99575
GRPRIKTWQADTSTT	PARP14	376	Q460N5
RAKSKSAESPSWTPA	ORC1	191	Q13415
RTRRSINSATDPWPA	ADAMTS9	71	Q9P2N4
SWPSEKARLTSTLPA	BLNK	141	Q8WV28
RSLIPSWRQPTAGDS	GAS2L2	366	Q8NHY3
SRRSSWNSLKHKPPS	CACNA1I	986	Q9P0X4
SDFPPETQRAWAKLR	CYGB	141	Q8WWM9
SLTPESSPELAKRSW	BRSK1	581	Q8TDC3
TISGPENVWIRKSSR	BRWD1	2251	Q9NSI6
SPSPSVRKRQVSLNW	LTBP4	96	Q8N2S1
NSSSHLLVRWKPPTQ	INSRR	616	P14616
WVLAPRPKRATASAL	FIMP	41	Q96LL3
ASQAPKSPSSEWLVR	GPATCH2L	441	Q9NWQ4
EWATTRSSLKAPPQR	KHDRBS2	321	Q5VWX1
PWAVSPRRKLISVDS	IL21R	166	Q9HBE5
NILTWGRSPSDSKTP	EML3	481	Q32P44
RPELRKTASSTVWQA	GPRIN2	36	O60269
DWRSPKQRGSLSPVT	GRIP1	836	Q9Y3R0
VIREPKPRSARWLST	FASN	701	P49327
KPRSARWLSTSIPEA	FASN	706	P49327
ASTPSSRPKEWRPEK	CDKL5	811	O76039
AWRTKPDNPRETVAA	C4orf54	1531	D6RIA3
PELIRQSWRAVSRSP	NGB	6	Q9NPG2
TWASPKLRASVSPLD	PCARE	876	A6NGG8
WVPQADKRRRSLPSS	PCARE	1001	A6NGG8
SSEEPSRKNPTRWST	PARD3	161	Q8TEW0
ENAWVKRSSNPPARS	EIF4B	481	P23588
LPAPKSVLRSRWHSA	PAOX	416	Q6QHF9
TAAPSLVAASPRTWR	MMP20	21	O60882
SKIASISNSPRDWRT	MINAR1	721	Q9UPX6
RWSLPSSSPKNSEDL	MROH5	356	Q6ZUA9
SPLVTPEESRKLRFW	PUSL1	206	Q8N0Z8
PTNRLPSDWLSLDKS	RUSC2	1401	Q8N2Y8
RSSRPWSPQSRAKTP	RSPH4A	56	Q5TD94
WVASNPRESRPSTLL	RXFP4	351	Q8TDU9
SPLSKFRSSERWTLP	SENP7	46	Q9BQF6
WKRNSLTPRTTVFPC	TRIM36	101	Q9NQ86
KLQEWLRSPRDAVSP	TRIM36	596	Q9NQ86
TSPAPWKRSRSRASP	SRRM2	1856	Q9UQ35
TSSKTPSVRDPNEWA	PRUNE2	821	Q8WUY3
ARPAQPTLWTAKLDR	TMEM132A	301	Q24JP5
PVSPSRAWSPRAKQA	SYNPO	891	Q8N3V7
RDSTSSLQRKKPPWL	RHBDF1	6	Q96CC6
AVDSNPPARLSLSWR	SIGLEC9	276	Q9Y336
QDSWPVSSALLSKRP	SHROOM2	1046	Q13796
PSSWSSLDQKRLCRP	SHROOM3	401	Q8TF72
QTWCPKTLSPSRSQR	PROSER3	31	Q2NL68
KWAPPLERSRLATTA	SLC17A7	196	Q9P2U7
AWRSSQRSTQKDPVP	XBP1	226	P17861
ALERWPSTSPKGERR	KIAA0753	401	Q2KHM9
SPQNLSPWDRTTRRV	PROB1	411	E7EW31
SPWDRTTRRVSSPLF	PROB1	416	E7EW31
RRKTGTLQPWNSDST	RACGAP1	246	Q9H0H5
SANKRWTPPRSIRFT	RHPN2	506	Q8IUC4
NPATDSWSAVRPLRQ	KBTBD11	386	O94819
TSSPSRSKQSEVPWA	TRIOBP	921	Q9H2D6
SLNRTPSVTEASPWR	STON2	296	Q8WXE9
PSWKSSFRQPRSLSG	ARHGAP22	426	Q7Z5H3
SSPRLSLAPAEAWKA	ROBO4	631	Q8WZ75
DKAPAQARPTVFRWT	PRKAB1	71	Q9Y478
PSRLPINRSGTWKRE	APC	2536	P25054
KSTRAPATTWPVRRG	ARMCX1	176	Q9P291
RLVARPDPTAEWKSV	ATG4D	286	Q86TL0
AEKSPGPIVSRTRSW	ZC3HC1	341	Q86WB0
LTSEWEIQPRTKRSS	ZNF562	86	Q6V9R5
RDVWSAPSSLRLPRK	USP43	1061	Q70EL4
TSWIDPRDRLTKPLS	WWC2	36	Q6AWC2
RTASIWVPPLQERNS	ZNF268	6	Q14587
WITRQEEPRAQSTPS	SPEN	2501	Q96T58
TPDSWNIPLTDARRK	SOBP	296	A7XYQ1
WSPRSSSLVSVRSKQ	SOGA1	1166	O94964
SLSRPCPNSSVWVRA	GEMIN5	1291	Q8TEQ6
ETALLTWRPPRASVT	TNC	1901	P24821
VWSTPSRKKPVLSAR	nan	21	A8MX80
RHRPKDAATPSRSTW	DHX38	201	Q92620
KRTEIISRSWFPSAP	YJU2B	246	P13994
DISRPRKPWQQTFSE	ZDHHC21	221	Q8IVQ6
PVFPVWKASSRRSNL	ZNF843	331	Q8N446
LKPLSDDPTVSASRW	PSMG2	231	Q969U7
KRASSWPSRTQNPVE	TEX33	176	O43247
WPNVAAVSITGRKRS	TKFC	336	Q3LXA3
VTHSSPPARLSWTQR	SIGLEC10	381	Q96LC7
SPEKRWASPRVARFA	TG	391	P01266
SSQSWREPSPPRKSS	ZFC3H1	186	O60293
PQSRLRKWTTVDSIS	TNRC6A	1531	Q8NDV7
WSAPSRKKPVLSARN	nan	21	A6NL46
WKNHISSRNTTPLPR	TNRC6B	1586	Q9UPQ9
TTTTLKWRPPNRIGA	MYBPC2	751	Q14324