Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionnuclear receptor activity

NR5A2 AHR NR4A1 NR3C1

6.16e-0560714GO:0004879
GeneOntologyMolecularFunctionligand-activated transcription factor activity

NR5A2 AHR NR4A1 NR3C1

6.57e-0561714GO:0098531
GeneOntologyMolecularFunctiontranscription coregulator binding

NR5A2 AHR PAX3 BSN RUNX3

1.42e-04140715GO:0001221
GeneOntologyBiologicalProcesscell proliferation in forebrain

IGF2BP1 NFIB NUMB FGFR2

7.77e-0638694GO:0021846
GeneOntologyBiologicalProcesspositive regulation of transcription by RNA polymerase II

PWWP2A HOXB3 RPS6KA5 EGR1 NFIB NR5A2 DVL2 AHR PAX3 FGFR2 PAX9 NR4A1 NR3C1 FUBP3 NIPBL LDB2

1.05e-0513906916GO:0045944
GeneOntologyBiologicalProcessanimal organ morphogenesis

HOXB3 COL11A2 NFIB INSL4 SEC24B NR5A2 DVL2 AHR NUMB PAX3 FGFR2 PAX9 NR3C1 NIPBL AHDC1

1.54e-0512696915GO:0009887
GeneOntologyBiologicalProcessmammary gland specification

PAX3 FGFR2

6.59e-054692GO:0060594
GeneOntologyBiologicalProcessmammary gland morphogenesis

INSL4 PAX3 FGFR2 NR3C1

6.66e-0565694GO:0060443
GeneOntologyBiologicalProcessmesenchymal cell proliferation involved in lung development

NFIB FGFR2

1.64e-046692GO:0060916
GeneOntologyBiologicalProcessnegative regulation of transcription by RNA polymerase II

HMBOX1 HOXB3 EGR1 NFIB AHR PAX3 FGFR2 NR3C1 RUNX3 NIPBL LDB2 MXI1

1.75e-0410536912GO:0000122
GeneOntologyBiologicalProcessnegative regulation of DNA-templated transcription

HMBOX1 HOXB3 RPS6KA5 EGR1 NFIB AHR PAX3 FGFR2 PAX9 NR3C1 RUNX3 NIPBL LDB2 MXI1

1.85e-0413996914GO:0045892
GeneOntologyBiologicalProcessnegative regulation of RNA biosynthetic process

HMBOX1 HOXB3 RPS6KA5 EGR1 NFIB AHR PAX3 FGFR2 PAX9 NR3C1 RUNX3 NIPBL LDB2 MXI1

2.06e-0414136914GO:1902679
GeneOntologyBiologicalProcessmammary gland development

INSL4 IRS2 PAX3 FGFR2 NR3C1

2.11e-04162695GO:0030879
GeneOntologyBiologicalProcessoutflow tract morphogenesis

SEC24B DVL2 FGFR2 NIPBL

2.79e-0494694GO:0003151
GeneOntologyBiologicalProcessmelanosome organization

PIKFYVE HPS5 LYST

3.00e-0439693GO:0032438
GeneOntologyBiologicalProcesspigment granule organization

PIKFYVE HPS5 LYST

3.24e-0440693GO:0048753
GeneOntologyBiologicalProcessgland morphogenesis

NFIB INSL4 PAX3 FGFR2 NR3C1

3.25e-04178695GO:0022612
GeneOntologyBiologicalProcessmammary gland formation

PAX3 FGFR2

3.91e-049692GO:0060592
GeneOntologyBiologicalProcesslung lobe development

SEC24B FGFR2

3.91e-049692GO:0060462
GeneOntologyBiologicalProcesslung lobe morphogenesis

SEC24B FGFR2

3.91e-049692GO:0060463
GeneOntologyBiologicalProcessregulation of epithelial cell proliferation involved in lung morphogenesis

NFIB FGFR2

3.91e-049692GO:2000794
GeneOntologyBiologicalProcesstube formation

NFIB SEC24B DVL2 PAX3 FGFR2

4.08e-04187695GO:0035148
MousePhenolethality during fetal growth through weaning, incomplete penetrance

CPEB2 PIKFYVE HOXB3 IGF2BP1 NFIB FUBP1 VCAN DVL2 AHR FRYL PAX3 FGFR2 PAX9 NR3C1 RUNX3 F5 NIPBL

3.90e-0611246117MP:0011112
MousePhenoabnormal branching involved in lung morphogenesis

NFIB FUBP1 FGFR2 NR3C1

1.38e-0534614MP:0011024
MousePhenoabnormal prostate gland morphology

EGR1 INSL4 AHR FGFR2 MXI1

1.60e-0573615MP:0001158
MousePhenoperinatal lethality

PIKFYVE HOXB3 IGF2BP1 NFIB FUBP1 VCAN SCN2A INSL4 DVL2 PAX3 FGFR2 PAX9 NR3C1 RUNX3 F5 AHDC1

1.86e-0511306116MP:0002081
MousePhenoabnormal prostate gland size

EGR1 INSL4 AHR FGFR2

3.24e-0542614MP:0004959
MousePhenoabnormal skin pigmentation

FRYL PAX3 FGFR2 HPS5 LYST

3.76e-0587615MP:0002095
MousePhenoabnormal pulmonary alveolar system morphology

PIKFYVE NFIB FUBP1 AHR PAX3 FGFR2 NR3C1 LYST

4.09e-05296618MP:0010899
MousePhenoabnormal mammary placode morphology

PAX3 FGFR2

5.60e-053612MP:0013721
MousePhenoabsent ultimobranchial body

PAX3 PAX9

5.60e-053612MP:0004914
MousePhenoperinatal lethality, incomplete penetrance

PIKFYVE HOXB3 IGF2BP1 NFIB FUBP1 DVL2 PAX3 NR3C1 RUNX3 F5

5.76e-055036110MP:0011090
MousePhenodecreased fetal size

IGF2BP1 NFIB FUBP1 VCAN FGFR2 NIPBL AHDC1

5.94e-05229617MP:0004200
MousePhenodecreased tail pigmentation

PAX3 HPS5 LYST

6.16e-0518613MP:0011277
MousePhenoabnormal prenatal body size

PIKFYVE IGF2BP1 EGR1 NFIB FUBP1 VCAN HGS SEC24B NR5A2 NUMB PAX3 FGFR2 HUWE1 NIPBL AHDC1

6.60e-0511166115MP:0010866
MousePhenoabnormal fetal size

IGF2BP1 NFIB FUBP1 VCAN FGFR2 NIPBL AHDC1

7.38e-05237617MP:0004198
MousePhenohypopigmentation

PAX3 FGFR2 HPS5 LYST

8.19e-0553614MP:0005408
MousePhenoabnormal dermal layer morphology

EGR1 VCAN FGFR2 LYST BGN

1.06e-04108615MP:0001243
MousePhenofused tracheal cartilage rings

FGFR2 PAX9

1.12e-044612MP:0004552
MousePhenodecreased circulating testosterone level

EGR1 NR5A2 IRS2 NR3C1

1.33e-0460614MP:0002780
MousePhenoabnormal skin coloration

IL12RB1 FRYL PAX3 FGFR2 HPS5 LYST

1.38e-04182616MP:0011239
MousePhenoabnormal intramembranous bone ossification

FGFR2 RUNX3 NIPBL AHDC1

1.42e-0461614MP:0008273
MousePhenosubmandibular gland hypoplasia

NFIB FGFR2

1.86e-045612MP:0009522
MousePhenoabnormal ear morphology

COL11A2 SEC24B PAX3 CACHD1 FGFR2 PAX9 BSN HPS5 LYST

1.86e-04470619MP:0002102
MousePhenoabnormal pulmonary acinus morphology

NFIB FUBP1 AHR PAX3 FGFR2 NR3C1 LYST

2.27e-04284617MP:0010911
MousePhenolimbs/digits/tail phenotype

IGF2BP1 EGR1 VCAN SEC24B CAST DVL2 PAX3 FGFR2 PAX9 RUNX3 HPS5 LYST NIPBL BGN SON

2.52e-0412586115MP:0005371
MousePhenorespiratory distress

NFIB SCN2A PAX3 FGFR2 PAX9 NR3C1

2.56e-04204616MP:0001954
MousePhenoabnormal ultimobranchial body morphology

PAX3 PAX9

2.78e-046612MP:0003955
MousePhenoabnormal cardiac outflow tract development

VCAN SEC24B DVL2 PAX3 FGFR2

2.91e-04134615MP:0006126
MousePhenoabnormal respiratory function

CPEB2 NFIB SCN2A PAX3 FGFR2 PAX9 NR3C1 RUNX3

3.22e-04399618MP:0002327
MousePhenoabnormal endolymphatic duct morphology

PAX3 CACHD1 FGFR2

3.26e-0431613MP:0006011
MousePhenoabnormal breathing pattern

CPEB2 NFIB SCN2A PAX3 FGFR2 PAX9 NR3C1

3.36e-04303617MP:0001951
MousePhenoabnormal lung development

NFIB FUBP1 FGFR2 NR3C1 LYST

3.80e-04142615MP:0001176
MousePhenoathyroidism

PAX3 FGFR2

3.88e-047612MP:0004663
MousePhenoabnormal platelet ADP level

HPS5 LYST

3.88e-047612MP:0009556
MousePhenodecreased platelet ADP level

HPS5 LYST

3.88e-047612MP:0009557
MousePhenoabnormal branching involved in terminal bronchiole morphogenesis

NFIB NR3C1

3.88e-047612MP:0011031
MousePhenoabsent thyroid gland

PAX3 FGFR2

3.88e-047612MP:0005314
MousePhenoarrest of tooth development

FGFR2 PAX9

3.88e-047612MP:0000118
MousePhenoaberrant origin of the right subclavian artery

SEC24B PAX3 PAX9

3.93e-0433613MP:0010465
MousePhenoabnormal somatic nervous system morphology

CPEB2 PIKFYVE HOXB3 EGR1 HGS SEC24B NUMB IRS2 PAX3 CACHD1 FGFR2 BSN RUNX3

3.94e-0410256113MP:0002752
MousePhenoabnormal fetal growth/weight/body size

IGF2BP1 NFIB FUBP1 VCAN FGFR2 NIPBL AHDC1

4.01e-04312617MP:0004197
MousePhenoabnormal respiratory system morphology

PIKFYVE COL11A2 EGR1 NFIB FUBP1 SEC24B AHR PAX3 FGFR2 PAX9 NR3C1 RUNX3 LYST

4.01e-0410276113MP:0002132
MousePhenoabnormal somite development

VCAN HGS DVL2 PAX3 HUWE1 F5

4.02e-04222616MP:0001688
MousePhenoabnormal lung morphology

PIKFYVE EGR1 NFIB FUBP1 SEC24B AHR PAX3 FGFR2 NR3C1 RUNX3 LYST

4.25e-047676111MP:0001175
MousePhenocyanosis

NFIB VCAN SCN2A DVL2 PAX3 NR3C1

4.42e-04226616MP:0001575
MousePhenoabnormal extraembryonic tissue morphology

PIKFYVE IGF2BP1 FUBP1 VCAN HGS SEC24B NR5A2 NUMB FRYL FGFR2 F5 NIPBL

4.74e-049086112MP:0002086
MousePhenoabnormal circulating testosterone level

EGR1 NR5A2 IRS2 NR3C1

4.88e-0484614MP:0005180
MousePhenoabnormal circulating androgen level

EGR1 NR5A2 IRS2 NR3C1

4.88e-0484614MP:0009819
MousePhenoabnormal blastocoele morphology

PIKFYVE NUP214 FGFR2

5.09e-0436613MP:0004963
MousePhenodecreased submandibular gland size

NFIB FGFR2

5.16e-048612MP:0009520
MousePhenoectopic thymus

PAX3 PAX9

5.16e-048612MP:0003007
MousePhenoabnormal bronchiole morphology

NFIB FGFR2 NR3C1

5.53e-0437613MP:0002267
MousePhenoabnormal aortic arch and aortic arch branch attachment

SEC24B PAX3 PAX9

5.53e-0437613MP:0010464
MousePhenoneonatal lethality

HOXB3 NFIB FUBP1 VCAN INSL4 PAX3 FGFR2 PAX9 NR3C1 RUNX3 F5

6.00e-047996111MP:0002058
MousePhenoabnormal cardiovascular development

VCAN HGS SEC24B DVL2 AHR NUMB A4GNT PAX3 FGFR2 PAX9 AHDC1

6.19e-048026111MP:0002925
MousePhenoabnormal tail pigmentation

PAX3 HPS5 LYST

6.46e-0439613MP:0005174
MousePhenoabnormal respiratory system development

NFIB FUBP1 FGFR2 NR3C1 LYST

6.55e-04160615MP:0003115
MousePhenoabnormal pharyngeal pouch morphology

PAX3 PAX9

6.61e-049612MP:0006031
MousePhenopostnatal lethality

CPEB2 PIKFYVE IGF2BP1 NFIB SCN2A AHR FRYL PAX3 FGFR2 PAX9 NR3C1 RUNX3 NIPBL

6.72e-0410846113MP:0002082
MousePhenoabnormal testosterone level

EGR1 NR5A2 IRS2 NR3C1

6.88e-0492614MP:0011385
MousePhenoabnormal right subclavian artery morphology

SEC24B PAX3 PAX9

6.96e-0440613MP:0010487
MousePhenoabnormal cochlea morphology

COL11A2 SEC24B PAX3 CACHD1 FGFR2 BSN

7.21e-04248616MP:0000031
MousePhenodecreased heart atrium size

FGFR2 NIPBL

8.24e-0410612MP:0031577
MousePhenoabnormal vestibuloocular reflex

AHR LYST

8.24e-0410612MP:0004844
MousePhenoabnormal terminal bronchiole morphology

NFIB NR3C1

8.24e-0410612MP:0002268
MousePhenoheart atrium hypoplasia

FGFR2 NIPBL

8.24e-0410612MP:0004055
MousePhenoabnormal mammary gland embryonic development

PAX3 FGFR2

8.24e-0410612MP:0004135
MousePhenoabnormal platelet ATP level

HPS5 LYST

8.24e-0410612MP:0009447
MousePhenodecreased platelet ATP level

HPS5 LYST

8.24e-0410612MP:0009448
MousePhenoabnormal oxygen level

NFIB VCAN SCN2A DVL2 PAX3 NR3C1

8.50e-04256616MP:0001574
MousePhenoimpaired lung alveolus development

FGFR2 NR3C1 LYST

9.22e-0444613MP:0006027
MousePhenoventricular septal defect

VCAN DVL2 PAX3 FGFR2 PAX9 NIPBL

9.40e-04261616MP:0010402
MousePhenoperinatal lethality, complete penetrance

NFIB FUBP1 VCAN SCN2A PAX3 FGFR2 PAX9 NR3C1 F5 AHDC1

9.41e-047126110MP:0011089
MousePhenoabnormal lung size

NFIB FUBP1 SEC24B FGFR2 NR3C1

9.56e-04174615MP:0004881
MousePhenoabnormal membranous labyrinth morphology

COL11A2 SEC24B PAX3 CACHD1 FGFR2 BSN

9.59e-04262616MP:0000035
MousePhenodecreased osteoblast cell number

FGFR2 RUNX3 BGN

9.85e-0445613MP:0004989
MousePhenoabnormal prostate gland development

INSL4 FGFR2

1.00e-0311612MP:0009735
MousePhenoabnormal dorsal root ganglion morphology

PIKFYVE NUMB PAX3 RUNX3

1.09e-03104614MP:0000961
MousePhenoabnormal neurocranium morphology

PAX3 CACHD1 FGFR2 PAX9 RUNX3 NIPBL

1.10e-03269616MP:0000074
MousePhenoabnormal hindbrain morphology

PIKFYVE NFIB FUBP1 HGS PAX3 FGFR2 LYST NIPBL

1.16e-03485618MP:0000841
MousePhenodecreased ear pigmentation

HPS5 LYST

1.20e-0312612MP:0011279
MousePhenoabnormal pons morphology

PIKFYVE NFIB HGS

1.26e-0349613MP:0000848
MousePhenoabnormal circulating progesterone level

EGR1 NR5A2 IRS2

1.34e-0350613MP:0005184
MousePhenoabnormal lung alveolus development

FGFR2 NR3C1 LYST

1.34e-0350613MP:0010995
MousePhenoabnormal common carotid artery morphology

PAX3 PAX9

1.42e-0313612MP:0012729
MousePhenoabnormal thyroid gland development

PAX3 PAX9

1.42e-0313612MP:0003421
MousePhenoabnormal auchene hair morphology

AHR RUNX3

1.42e-0313612MP:0000405
MousePhenodecreased spinal cord size

HGS RUNX3

1.42e-0313612MP:0000956
MousePhenoabnormal prenatal growth/weight/body size

PIKFYVE IGF2BP1 EGR1 NFIB FUBP1 VCAN HGS SEC24B NR5A2 NUMB PAX3 FGFR2 HUWE1 NIPBL AHDC1

1.53e-0314936115MP:0004196
MousePhenoabnormal placenta labyrinth morphology

FUBP1 NUMB FRYL FGFR2 NIPBL

1.55e-03194615MP:0001716
MousePhenosmall lung

NFIB FUBP1 SEC24B FGFR2

1.58e-03115614MP:0003641
MousePhenoabnormal trabecular bone morphology

EGR1 HGS FGFR2 RUNX3 BGN SON

1.59e-03289616MP:0000130
MousePhenoabnormal choroid pigmentation

HPS5 LYST

1.65e-0314612MP:0005100
MousePhenodecreased molar number

FGFR2 PAX9

1.65e-0314612MP:0006400
MousePhenopremature intramembranous bone ossification

FGFR2 AHDC1

1.65e-0314612MP:0003418
MousePhenothin placenta labyrinth

FUBP1 NUMB

1.65e-0314612MP:0011523
MousePhenopremature cranial suture closure

FGFR2 AHDC1

1.65e-0314612MP:0000081
MousePhenopremature craniofacial suture closure

FGFR2 AHDC1

1.65e-0314612MP:0030435
MousePhenoabnormal Langerhans cell morphology

AHR RUNX3

1.65e-0314612MP:0008117
MousePhenohearing/vestibular/ear phenotype

COL11A2 SEC24B AHR PAX3 CACHD1 FGFR2 PAX9 BSN HPS5 LYST NIPBL

1.66e-039056111MP:0005377
MousePhenopulmonary hypoplasia

NFIB FUBP1 FGFR2

1.67e-0354613MP:0001178
DomainKH_1

IGF2BP1 FUBP1 FUBP3 HDLBP

1.43e-0538734PF00013
Domain-

IGF2BP1 FUBP1 FUBP3 HDLBP

1.59e-05397343.30.1370.10
DomainKH

IGF2BP1 FUBP1 FUBP3 HDLBP

1.76e-0540734SM00322
DomainKH_dom

IGF2BP1 FUBP1 FUBP3 HDLBP

1.76e-0540734IPR004087
DomainKH_TYPE_1

IGF2BP1 FUBP1 FUBP3 HDLBP

2.15e-0542734PS50084
DomainKH_dom_type_1

IGF2BP1 FUBP1 FUBP3 HDLBP

2.59e-0544734IPR004088
DomainPAX

PAX3 PAX9

5.33e-049732SM00351
DomainPaired_dom

PAX3 PAX9

5.33e-049732IPR001523
DomainPAIRED_2

PAX3 PAX9

5.33e-049732PS51057
DomainPAX

PAX3 PAX9

5.33e-049732PF00292
DomainPAIRED_1

PAX3 PAX9

5.33e-049732PS00034
Domainzf-C4

NR5A2 NR4A1 NR3C1

7.71e-0446733PF00105
DomainZnf_hrmn_rcpt

NR5A2 NR4A1 NR3C1

7.71e-0446733IPR001628
DomainNuclear_hrmn_rcpt

NR5A2 NR4A1 NR3C1

7.71e-0446733IPR001723
DomainNUCLEAR_REC_DBD_2

NR5A2 NR4A1 NR3C1

7.71e-0446733PS51030
DomainNUCLEAR_REC_DBD_1

NR5A2 NR4A1 NR3C1

7.71e-0446733PS00031
DomainZnF_C4

NR5A2 NR4A1 NR3C1

7.71e-0446733SM00399
Domain-

NR5A2 NR4A1 NR3C1

8.21e-04477331.10.565.10
DomainHOLI

NR5A2 NR4A1 NR3C1

8.73e-0448733SM00430
DomainNucl_hrmn_rcpt_lig-bd

NR5A2 NR4A1 NR3C1

8.73e-0448733IPR000536
DomainHormone_recep

NR5A2 NR4A1 NR3C1

8.73e-0448733PF00104
Domain-

NR5A2 NR4A1 NR3C1

1.44e-03577333.30.50.10
DomainZnf_NHR/GATA

NR5A2 NR4A1 NR3C1

1.52e-0358733IPR013088
DomainDS_RBD

ADARB2 SON

3.02e-0321732PS50137
DomainDEP

PIKFYVE DVL2

3.31e-0322732PF00610
DomainDEP

PIKFYVE DVL2

3.31e-0322732PS50186
DomainDEP

PIKFYVE DVL2

3.31e-0322732SM00049
DomainG_patch

ERVK-6 SON

3.61e-0323732SM00443
DomainG_patch_dom

ERVK-6 SON

3.61e-0323732IPR000467
DomainDEP_dom

PIKFYVE DVL2

3.61e-0323732IPR000591
DomainG_PATCH

ERVK-6 SON

3.61e-0323732PS50174
DomainG-patch

ERVK-6 SON

3.61e-0323732PF01585
DomainUIM

HGS HUWE1

3.93e-0324732PS50330
DomainUIM_dom

HGS HUWE1

4.26e-0325732IPR003903
Domain-

ADARB2 SON

4.96e-03277323.30.160.20
DomainPID

MAPK8IP1 NUMB

5.33e-0328732PF00640
DomaindsRBD_dom

ADARB2 SON

5.33e-0328732IPR014720
DomainFYVE

PIKFYVE HGS

5.71e-0329732PF01363
DomainFYVE

PIKFYVE HGS

5.71e-0329732SM00064
DomainPH_dom-like

MAPK8IP1 PSD3 NUMB IRS2 ARHGEF11 LYST

6.39e-03426736IPR011993
DomainPID

MAPK8IP1 NUMB

6.93e-0332732PS01179
DomainZnf_FYVE-rel

PIKFYVE HGS

7.80e-0334732IPR017455
PathwayWP_SEROTONIN_RECEPTOR_467_AND_NR3C_SIGNALING

RPS6KA5 EGR1 NR3C1

5.21e-0519553M39358
PathwayWP_BRAINDERIVED_NEUROTROPHIC_FACTOR_BDNF_SIGNALING

IGF2BP1 RPS6KA5 EGR1 PRKAA2 IRS2

2.39e-04144555M39691
PathwayWP_VEGFAVEGFR2_SIGNALING

KANK1 RPS6KA5 EGR1 HGS PRKAA2 NUMB NR4A1 LDB2

2.47e-04431558M39729
PathwayWP_INSULIN_SIGNALING

RPS6KA5 EGR1 PIK3C2G PRKAA2 IRS2

3.89e-04160555M39482
PathwayREACTOME_DEFECTIVE_CHST14_CAUSES_EDS_MUSCULOCONTRACTURAL_TYPE

VCAN BGN

4.12e-048552M27260
PathwayREACTOME_DEFECTIVE_CHSY1_CAUSES_TPBS

VCAN BGN

4.12e-048552M27261
PathwayREACTOME_DEFECTIVE_CHST3_CAUSES_SEDCJD

VCAN BGN

4.12e-048552M27259
PathwayWP_NUCLEAR_RECEPTORS

NR5A2 NR4A1 NR3C1

4.30e-0438553M39657
PathwayWP_NUCLEAR_RECEPTORS

NR5A2 NR4A1 NR3C1

4.30e-0438553MM15865
PathwayWP_NEURAL_CREST_DIFFERENTIATION

COL11A2 DVL2 PAX3 FGFR2

5.49e-0497554MM15926
PathwayWP_NEURAL_CREST_DIFFERENTIATION

COL11A2 DVL2 PAX3 FGFR2

6.40e-04101554M39448
PathwayREACTOME_DERMATAN_SULFATE_BIOSYNTHESIS

VCAN BGN

6.59e-0410552MM14801
PathwayBIOCARTA_NPC_PATHWAY

NUP214 NUP153

8.04e-0411552M22033
PathwayREACTOME_DERMATAN_SULFATE_BIOSYNTHESIS

VCAN BGN

8.04e-0411552M27105
PathwayWP_MACROPHAGESTIMULATING_PROTEIN_MSP_SIGNALING

RPS6KA5 EGR1 PRKAA2 NR4A1

8.23e-04108554M48078
PathwayWP_SPINAL_CORD_INJURY

LILRA1 EGR1 VCAN NR4A1

8.23e-04108554MM15954
PathwayREACTOME_NUCLEAR_RECEPTOR_TRANSCRIPTION_PATHWAY

NR5A2 NR4A1 NR3C1

8.58e-0448553MM14987
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

HGS SEC24B DVL2 PSD3 NUMB IRS2 NUP214 CACHD1 THSD1 NUP153 HDLBP

2.61e-07708731139231216
Pubmed

A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.

HMBOX1 PIKFYVE GTF3C1 ZNF185 NR5A2 AHR PAX3 PAX9 NR4A1 NR3C1 LDB2

2.64e-07709731122988430
Pubmed

Fibroblast Growth Factor 2 Modulates Hypothalamic Pituitary Axis Activity and Anxiety Behavior Through Glucocorticoid Receptors.

EGR1 FGFR2 NR3C1

3.09e-07773327133954
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

IGF2BP1 SEC24B CAST DVL2 NUMB IRS2 NUP214 NR3C1 NIPBL NUP153 SON HDLBP

5.36e-07934731233916271
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

GTF3C1 RPS6KA5 FUBP1 CAST IRS2 NUP214 HUWE1 NIPBL NUP153 SON HDLBP

6.27e-07774731115302935
Pubmed

Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.

NUP214 NR3C1 NUP153

1.05e-061073319581287
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

IGF2BP1 GTF3C1 FUBP1 NUMB IRS2 HUWE1 NIPBL NUP153 SON

1.10e-0650373916964243
Pubmed

Inhibition of RIF1 by SCAI Allows BRCA1-Mediated Repair.

BSN AHDC1 NUP153

1.93e-061273328700933
Pubmed

Pax3 and Pax7 play essential safeguard functions against environmental stress-induced birth defects.

AHR PAX3 PAX9

1.93e-061273325800090
Pubmed

Impact of cytosine methylation on DNA binding specificities of human transcription factors.

HMBOX1 EGR1 NFIB NR5A2 PAX3 PAX9 NR4A1 NR3C1 RUNX3

2.09e-0654473928473536
Pubmed

An atlas of combinatorial transcriptional regulation in mouse and man.

GTF3C1 EGR1 NR5A2 AHR PAX3 PAX9 NR3C1 RUNX3 FUBP3 LDB2 MXI1

2.11e-06877731120211142
Pubmed

A census of human transcription factors: function, expression and evolution.

HMBOX1 HOXB3 EGR1 NFIB NR5A2 PAX3 PAX9 NR4A1 NR3C1 RUNX3 MXI1

2.94e-06908731119274049
Pubmed

Expression of glucocorticoid receptor and early growth response gene 1 during postnatal development of two inbred strains of mice exposed to early life stress.

EGR1 NR3C1

4.35e-06273220453467
Pubmed

Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity.

VCAN BGN

4.35e-06273232610121
Pubmed

A transcription factor-based mechanism for mouse heterochromatin formation.

PAX3 PAX9

4.35e-06273222983563
Pubmed

An evidence for regulatory cross-talk between aryl hydrocarbon receptor and glucocorticoid receptor in HepG2 cells.

AHR NR3C1

4.35e-06273217552871
Pubmed

Cooperation of LIM domain-binding 2 (LDB2) with EGR in the pathogenesis of schizophrenia.

EGR1 LDB2

4.35e-06273233656268
Pubmed

The nuclear receptor nr4a1 controls CD8 T cell development through transcriptional suppression of runx3.

NR4A1 RUNX3

4.35e-06273225762306
Pubmed

Hrs regulates the endocytic sorting of the fibroblast growth factor receptor 2b.

HGS FGFR2

4.35e-06273219362549
Pubmed

Proteoglycan Remodeling Is Accelerated in Females with Angina Pectoris and Diffuse Myocardial Fibrosis: the iPOWER Study.

VCAN BGN

4.35e-06273233649986
Pubmed

Runx3 Induces a Cell Shape Change and Suppresses Migration and Metastasis of Melanoma Cells by Altering a Transcriptional Profile.

MALL RUNX3

4.35e-06273233672337
Pubmed

The MAPK pathway and Egr-1 mediate stress-related behavioral effects of glucocorticoids.

EGR1 NR3C1

4.35e-06273215834420
Pubmed

Quantitative trait loci for body weight in the intercross between SM/J and A/J mice.

EGR1 NR3C1

4.35e-06273211515095
Pubmed

Crosstalk between activated forms of the aryl hydrocarbon receptor and glucocorticoid receptor.

AHR NR3C1

4.35e-06273219463884
Pubmed

Kindling and associated mossy fibre sprouting are not affected in mice deficient of NGFI-A/NGFI-B genes.

EGR1 NR4A1

4.35e-0627329466414
Pubmed

Altered subcellular distribution of MSK1 induced by glucocorticoids contributes to NF-kappaB inhibition.

RPS6KA5 NR3C1

4.35e-06273218511904
Pubmed

Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia.

COL11A2 AHR PAX3 FGFR2 PAX9 NR3C1 NIPBL

6.31e-0633173720634891
Pubmed

A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.

CPEB2 IGF2BP1 FUBP1 ADARB2 FUBP3 SON HDLBP

8.58e-0634773716033648
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

GTF3C1 FRYL NUP214 HUWE1 FUBP3 NIPBL NUP153 SON HDLBP

9.14e-0665373922586326
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

IGF2BP1 GTF3C1 FUBP1 NUP214 HUWE1 F5 FUBP3 NIPBL NUP153 SON HDLBP

9.17e-061024731124711643
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

PDPR HGS SEC24B PSD3 NUMB CACHD1 HID1 HUWE1 PTPRU NUP153 HDLBP

1.15e-051049731127880917
Pubmed

Herpesvirus deconjugases inhibit the IFN response by promoting TRIM25 autoubiquitination and functional inactivation of the RIG-I signalosome.

HGS HUWE1 NUP153 HDLBP

1.24e-056773429357390
Pubmed

The FUSE binding proteins FBP1 and FBP3 are potential c-myc regulators in renal, but not in prostate and bladder cancer.

FUBP1 FUBP3

1.30e-05373219087307
Pubmed

Profiling of enantiopure drugs towards aryl hydrocarbon (AhR), glucocorticoid (GR) and pregnane X (PXR) receptors in human reporter cell lines.

AHR NR3C1

1.30e-05373224316275
Pubmed

Abundance and location of proteoglycans and hyaluronan within normal and myxomatous mitral valves.

VCAN BGN

1.30e-05373218621549
Pubmed

NOT, a human immediate-early response gene closely related to the steroid/thyroid hormone receptor NAK1/TR3.

NR4A1 NR3C1

1.30e-0537327877627
Pubmed

A cellular factor stimulates ligand-dependent release of hsp90 from the basic helix-loop-helix dioxin receptor.

AHR NR3C1

1.30e-0537328139547
Pubmed

Differential expression of TIS21 and TIS1 genes in the various organs of Balb/c mice, thymic carcinoma tissues and human cancer cell lines.

EGR1 NR4A1

1.30e-0537327768965
Pubmed

The methylated-DNA binding protein MBD2 enhances NGFI-A (egr-1)-mediated transcriptional activation of the glucocorticoid receptor.

EGR1 NR3C1

1.30e-05373225135974
Pubmed

Protein-protein interactions and transcriptional antagonism between the subfamily of NGFI-B/Nur77 orphan nuclear receptors and glucocorticoid receptor.

NR4A1 NR3C1

1.30e-05373215591535
Pubmed

PAX3 Confers Functional Heterogeneity in Skeletal Muscle Stem Cell Responses to Environmental Stress.

AHR PAX3

1.30e-05373231006622
Pubmed

Nucleoporins nup98 and nup214 participate in nuclear export of human immunodeficiency virus type 1 Rev.

NUP214 NUP153

1.30e-0537329847314
Pubmed

Serum amyloid A-containing HDL binds adipocyte-derived versican and macrophage-derived biglycan, reducing its antiinflammatory properties.

VCAN BGN

1.30e-05373232970631
Pubmed

The transcription factor early growth response 1 (Egr-1) advances differentiation of pre-B and immature B cells.

EGR1 NR4A1

1.30e-0537329858508
Pubmed

Smad2 nucleocytoplasmic shuttling by nucleoporins CAN/Nup214 and Nup153 feeds TGFbeta signaling complexes in the cytoplasm and nucleus.

NUP214 NUP153

1.30e-05373212191473
Pubmed

Differential proteoglycan and hyaluronan distribution in calcified aortic valves.

VCAN BGN

1.30e-05373221185747
Pubmed

The far upstream element-binding proteins comprise an ancient family of single-strand DNA-binding transactivators.

FUBP1 FUBP3

1.30e-0537328940189
Pubmed

Pre-eclampsia-associated alterations in decorin, biglycan and versican of the umbilical cord vein wall.

VCAN BGN

1.30e-05373217097211
Pubmed

Insulin signaling and reduced glucocorticoid receptor activity attenuate postprandial gene expression in liver.

IRS2 NR3C1

1.30e-05373230532187
Pubmed

Activated glucocorticoid receptor interacts with the INHAT component Set/TAF-Ibeta and releases it from a glucocorticoid-responsive gene promoter, relieving repression: implications for the pathogenesis of glucocorticoid resistance in acute undifferentiated leukemia with Set-Can translocation.

NUP214 NR3C1

1.30e-05373218096310
Pubmed

Cloning and subcellular localization of a human phosphatidylinositol 3-phosphate 5-kinase, PIKfyve/Fab1.

PIKFYVE HGS

1.30e-05373216448788
Pubmed

The nuclear pore complex: a new dynamic in HIV-1 replication.

NUP214 NUP153

1.30e-05373221327100
Pubmed

Mutational definition of functional domains within the Rev homolog encoded by human endogenous retrovirus K.

ERVK-6 NUP214

1.30e-05373211000203
Pubmed

Nuclear receptors in Leydig cell gene expression and function.

NR5A2 NR4A1 NR3C1

1.33e-052273320375256
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

HMBOX1 PWWP2A GTF3C1 NFIB NUP214 NR4A1 FUBP3 NIPBL AHDC1 NUP153 MXI1 SON

1.51e-051294731230804502
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

HGS SEC24B DVL2 NUMB FUBP3 NUP153

1.97e-0526373634702444
Pubmed

Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.

HMBOX1 HOXB3 NR5A2 PAX3 NR4A1 NR3C1

1.97e-0526373620932939
Pubmed

Huwe1-mediated ubiquitylation of dishevelled defines a negative feedback loop in the Wnt signaling pathway.

DVL2 HUWE1

2.60e-05473224643799
Pubmed

PAX3-FOXO1 controls expression of the p57Kip2 cell-cycle regulator through degradation of EGR1.

EGR1 PAX3

2.60e-05473217986608
Pubmed

Insulin receptor substrate 1/2 (IRS1/2) regulates Wnt/β-catenin signaling through blocking autophagic degradation of dishevelled2.

DVL2 IRS2

2.60e-05473224616100
Pubmed

The Ah receptor recruits IKKα to its target binding motifs to phosphorylate serine-10 in histone H3 required for transcriptional activation.

RPS6KA5 AHR

2.60e-05473224519526
Pubmed

Lysyl oxidase (Lox) maps between Grl-1 and Adrb-2 on mouse chromosome 18.

EGR1 NR3C1

2.60e-0547328094989
Pubmed

Planar cell polarity links axes of spatial dynamics in neural-tube closure.

DVL2 ARHGEF11

2.60e-05473222632972
Pubmed

AMPK regulates metabolic actions of glucocorticoids by phosphorylating the glucocorticoid receptor through p38 MAPK.

PRKAA2 NR3C1

2.60e-05473220660302
Pubmed

An ancient family of human endogenous retroviruses encodes a functional homolog of the HIV-1 Rev protein.

ERVK-6 NUP214

2.60e-05473210557333
Pubmed

Aryl hydrocarbon receptor is activated by glucose and regulates the thrombospondin-1 gene promoter in endothelial cells.

EGR1 AHR

2.60e-05473218515748
Pubmed

Phospholipase A2 type II binds to extracellular matrix biglycan: modulation of its activity on LDL by colocalization in glycosaminoglycan matrixes.

VCAN BGN

2.60e-0547329848887
Pubmed

The IGF system in in-vitro human decidualization.

IGF2BP1 IRS2

2.60e-05473219038974
Pubmed

RT-PCR quantification of AHR, ARNT, GR, and CYP1A1 mRNA in craniofacial tissues of embryonic mice exposed to 2,3,7,8-tetrachlorodibenzo-p-dioxin and hydrocortisone.

AHR NR3C1

2.60e-05473210048155
Pubmed

Lack of metformin effect on mouse embryo AMPK activity: implications for metformin treatment during pregnancy.

PRKAA2 PAX3

2.60e-05473223983188
Pubmed

Maternal transmission effects of the PAX genes among cleft case-parent trios from four populations.

PAX3 PAX9

2.60e-05473219142206
Pubmed

Merkel Cell-Driven BDNF Signaling Specifies SAI Neuron Molecular and Electrophysiological Phenotypes.

EGR1 NR4A1 RUNX3

2.80e-052873327076431
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

HMBOX1 GTF3C1 NFIB HGS PAX3 HUWE1 RUNX3 SON

3.07e-0558373829844126
Pubmed

Axial skeleton anterior-posterior patterning is regulated through feedback regulation between Meis transcription factors and retinoic acid.

HOXB3 PAX3 PAX9

3.12e-052973333298461
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

DVL2 FGFR2 NIPBL HDLBP

3.33e-058673437253089
Pubmed

Rearrangement of the Protein Phosphatase 1 Interactome During Heart Failure Progression.

IGF2BP1 FUBP1 FRYL IRS2 PRRC1

3.38e-0517473529669786
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

EGR1 NUMB NUP214 BSN PRRC1 NUP153 SON

3.39e-0543073735044719
Pubmed

An inducible CRISPR/Cas9 screen identifies DTX2 as a transcriptional regulator of human telomerase.

NFIB NUMB ARHGEF11 FUBP3 NUP153

3.97e-0518073535198878
Pubmed

Distinct domain utilization by Smad3 and Smad4 for nucleoporin interaction and nuclear import.

NUP214 NUP153

4.33e-05573212917407
Pubmed

The N-terminal domain of the mammalian nucleoporin p62 interacts with other nucleoporins of the FXFG family during interphase.

NUP214 NUP153

4.33e-05573216730000
Pubmed

Steady-state nuclear localization of exportin-t involves RanGTP binding and two distinct nuclear pore complex interaction domains.

NUP214 NUP153

4.33e-05573212138183
Pubmed

Exportin-5, a novel karyopherin, mediates nuclear export of double-stranded RNA binding proteins.

NUP214 NUP153

4.33e-05573211777942
Pubmed

A giant nucleopore protein that binds Ran/TC4.

NUP214 NUP153

4.33e-0557327603572
Pubmed

In vivo dissection of a clustered-CTCF domain boundary reveals developmental principles of regulatory insulation.

PAX3 FGFR2

4.33e-05573235817979
Pubmed

Analysis of atherosclerosis susceptibility in mice with genetic defects in platelet function.

HPS5 LYST

4.33e-0557322369371
Pubmed

The growth factor midkine is modulated by both glucocorticoid and retinoid in fetal lung development.

VCAN NR3C1

4.33e-05573212495930
Pubmed

Mapping of multiple intestinal neoplasia (Min) to proximal chromosome 18 of the mouse.

EGR1 NR3C1

4.33e-0557328094372
Pubmed

Genomic analysis of mouse retinal development.

EGR1 PIK3C2G PLK5 HGS DVL2 PSD3 FRYL FGFR2 BSN LDB2

4.68e-051006731015226823
Pubmed

Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.

CPEB2 NFIB FUBP1 NUP214 FUBP3 AHDC1 NUP153

4.99e-0545773732344865
Pubmed

Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.

PAX3 NUP214 NUP153

5.07e-053473318539113
Pubmed

Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.

HMBOX1 IGF2BP1 NUP214 FUBP3

6.25e-0510173426949739
Pubmed

Tumor promoter-inducible genes are differentially expressed in the developing mouse.

EGR1 NR4A1

6.48e-0567323185562
Pubmed

Differential expression of glycosaminoglycans and proteoglycans in the migratory pathway of the primordial germ cells of the mouse.

VCAN BGN

6.48e-05673212122449
Pubmed

Over-expression of the chondroitin sulphate proteoglycan versican is associated with defective neural crest migration in the Pax3 mutant mouse (splotch).

VCAN PAX3

6.48e-0567329486530
Pubmed

Gli3-mediated somitic Fgf10 expression gradients are required for the induction and patterning of mammary epithelium along the embryonic axes.

PAX3 FGFR2

6.48e-05673216720875
Pubmed

Notochord-dependent expression of MFH1 and PAX1 cooperates to maintain the proliferation of sclerotome cells during the vertebral column development.

PAX3 PAX9

6.48e-05673210364424
Pubmed

Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice.

NR5A2 AHR

6.48e-05673215798202
Pubmed

Loss of Dact1 disrupts planar cell polarity signaling by altering dishevelled activity and leads to posterior malformation in mice.

DVL2 PAX3

6.48e-05673220145239
Pubmed

Digital quantification of human eye color highlights genetic association of three new loci.

HGS LYST

6.48e-05673220463881
Pubmed

Deletion of Pax1 scoliosis-associated regulatory elements leads to a female-biased tail abnormality.

COL11A2 PAX9

6.48e-05673238461417
InteractionCTNNB1 interactions

HMBOX1 IGF2BP1 EGR1 SEC24B NR5A2 DVL2 USP43 AHR NUMB PAX3 NUP214 HUWE1 NR4A1 NR3C1 PTPRU HDLBP

4.04e-0710097216int:CTNNB1
InteractionKHSRP interactions

IGF2BP1 FUBP1 SEC24B HUWE1 NR4A1 FUBP3 NIPBL HDLBP

1.39e-05308728int:KHSRP
InteractionFMR1 interactions

HMBOX1 IGF2BP1 FUBP1 DVL2 NR3C1 BSN FUBP3 NIPBL LDB2 HDLBP

1.99e-055367210int:FMR1
InteractionEP300 interactions

HOXB3 IGF2BP1 GTF3C1 RPS6KA5 EGR1 SEC24B DVL2 AHR PAX9 NR4A1 NR3C1 BSN RUNX3 FUBP3 LDB2 SON

2.73e-0514017216int:EP300
InteractionDCAF7 interactions

IGF2BP1 RPS6KA5 SEC24B PRKAA2 NUMB PAX9 NIPBL HDLBP

4.95e-05368728int:DCAF7
InteractionKCNA3 interactions

HGS SEC24B DVL2 PSD3 NUMB IRS2 NUP214 CACHD1 THSD1 BSN NUP153 HDLBP

5.54e-058717212int:KCNA3
InteractionTLE3 interactions

EGR1 NFIB NR5A2 PAX9 NR3C1 NIPBL AHDC1 SON

5.76e-05376728int:TLE3
GeneFamilyPaired boxes

PAX3 PAX9

2.25e-049462675
GeneFamilyNuclear hormone receptors

NR5A2 NR4A1 NR3C1

2.62e-044946371
GeneFamilyZinc fingers FYVE-type|Pleckstrin homology domain containing|Rho guanine nucleotide exchange factors

PIKFYVE HGS

2.81e-033146281
GeneFamilyNucleoporins

NUP214 NUP153

2.99e-03324621051
CoexpressionBUSSLINGER_GASTRIC_NECK_CELLS

COL11A2 EGR1 PIK3C2G A4GNT NR4A1 HDLBP

6.34e-1036726M40008
CoexpressionGSE29618_MONOCYTE_VS_PDC_UP

LILRA1 EGR1 CAST IRS2 NUP214 F5 LYST

1.27e-06199727M4945
CoexpressionGSE22886_DC_VS_MONOCYTE_DN

LILRA1 RPS6KA5 VCAN IRS2 NUP214 F5 LYST

1.31e-06200727M4472
CoexpressionDAZARD_RESPONSE_TO_UV_NHEK_DN

PIKFYVE KANK1 PSD3 AHR FRYL FGFR2 AHDC1 NUP153

1.70e-06300728M8702
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_DN

PIKFYVE NFIB FUBP1 SEC24B PSD3 NUMB FRYL NR3C1 NIPBL AHDC1 NUP153 SON

3.46e-068567212M4500
CoexpressionGSE3920_IFNA_VS_IFNG_TREATED_ENDOTHELIAL_CELL_UP

CPEB2 EGR1 DNAJA4 FRYL NR4A1 SON

7.47e-06170726M6697
CoexpressionGSE6269_HEALTHY_VS_STAPH_PNEUMO_INF_PBMC_DN

EGR1 VCAN CAST FGFR2 ARHGEF11 F5

7.47e-06170726M5649
CoexpressionGSE37301_MULTIPOTENT_PROGENITOR_VS_LYMPHOID_PRIMED_MPP_DN

MAPK8IP1 RPS6KA5 IRS2 NR4A1 NR3C1 MAPKBP1

1.07e-05181726M8889
CoexpressionNAKAYA_B_CELL_FLUARIX_FLUVIRIN_AGE_18_50YO_7DY_DN

MAPK8IP1 NFIB PSD3 PAX3 FGFR2 LYST KIAA1614

1.64e-05294727M41112
CoexpressionIKEDA_MIR30_TARGETS_UP

CPEB2 NFIB CAST IRS2 SON

1.72e-05116725M2379
CoexpressionIKEDA_MIR30_TARGETS_UP

CPEB2 NFIB CAST IRS2 SON

1.79e-05117725MM931
CoexpressionBROWNE_HCMV_INFECTION_10HR_DN

AHR NR3C1 NIPBL SON

1.85e-0557724M8416
CoexpressionGSE43955_TGFB_IL6_VS_TGFB_IL6_IL23_TH17_ACT_CD4_TCELL_52H_DN

CPEB2 COL11A2 EGR1 AHR IRS2 LYST

1.88e-05200726M9668
CoexpressionGSE29618_MONOCYTE_VS_MDC_DAY7_FLU_VACCINE_UP

EGR1 VCAN ZNF185 CAST F5 MXI1

1.88e-05200726M4966
CoexpressionGRUETZMANN_PANCREATIC_CANCER_DN

KANK1 GTF3C1 NFIB NR5A2 MXI1 HDLBP

1.88e-05200726M10431
CoexpressionBUSSLINGER_GASTRIC_PREZYMOGENIC_CELLS

EGR1 PIK3C2G NFIB HDLBP

2.27e-0560724M40007
CoexpressionDACOSTA_UV_RESPONSE_VIA_ERCC3_COMMON_DN

PIKFYVE NFIB FUBP1 SEC24B NUMB FRYL NR3C1 NUP153

4.16e-05466728M13522
CoexpressionRUTELLA_RESPONSE_TO_HGF_DN

EGR1 VCAN ZNF185 NUP214 RUNX3 SON

5.22e-05240726M6413
CoexpressionNEMETH_INFLAMMATORY_RESPONSE_LPS_DN

COL11A2 NUMB MXI1

7.65e-0530723MM1154
CoexpressionHOEK_NK_CELL_2011_2012_TIV_3D_VS_0DY_ADULT_3D_DN

LILRA1 EGR1 VCAN IRS2 NR4A1 ARHGEF11

7.79e-05258726M41144
CoexpressionBUYTAERT_PHOTODYNAMIC_THERAPY_STRESS_UP

HMBOX1 RPS6KA5 SEC24B AHR NUMB IRS2 LYST NIPBL PRRC1 MXI1

8.05e-058227210M6782
CoexpressionNEMETH_INFLAMMATORY_RESPONSE_LPS_DN

COL11A2 NUMB MXI1

8.45e-0531723M1452
CoexpressionLU_AGING_BRAIN_UP

KANK1 VCAN CAST FRYL FGFR2 NIPBL

8.65e-05263726M5547
CoexpressionTRAVAGLINI_LUNG_CLASSICAL_MONOCYTE_CELL

VCAN CAST AHR NUMB IRS2 NUP214

9.99e-05270726M41699
CoexpressionDESCARTES_ORGANOGENESIS_ENDOTHELIAL_CELLS

MALL USP43 NUMB NR4A1 THSD1 LDB2

1.04e-04272726MM3634
CoexpressionCUI_TCF21_TARGETS_2_DN

CPEB2 KANK1 RPS6KA5 ZNF185 CAST PSD3 FRYL LYST LDB2 SON

1.10e-048547210M1533
CoexpressionFEKIR_HEPARG_SIDE_POP_VS_HEPARG_UP

NFIB VCAN USP43 AHR

1.12e-0490724M48360
CoexpressionCUI_TCF21_TARGETS_2_DN

CPEB2 KANK1 RPS6KA5 ZNF185 CAST PSD3 FRYL LYST LDB2 SON

1.52e-048887210MM1018
CoexpressionTONKS_TARGETS_OF_RUNX1_RUNX1T1_FUSION_HSC_UP

RPS6KA5 MALL VCAN AHR MXI1

1.54e-04184725M3804
CoexpressionDORN_ADENOVIRUS_INFECTION_32HR_DN

FUBP1 NR4A1 FUBP3

1.56e-0438723M15590
CoexpressionTANAKA_METHYLATED_IN_ESOPHAGEAL_CARCINOMA

DNAJA4 NFIB PAX9 ADARB2

1.81e-04102724M14455
CoexpressionP53_DN.V1_DN

KANK1 VCAN NR4A1 RUNX3 LYST

1.97e-04194725M2697
CoexpressionDORN_ADENOVIRUS_INFECTION_24HR_DN

FUBP1 NR4A1 FUBP3

2.11e-0442723M8825
CoexpressionAMIT_EGF_RESPONSE_40_HELA

EGR1 NFIB NR4A1

2.11e-0442723M4204
CoexpressionGSE360_CTRL_VS_L_MAJOR_DC_DN

NFIB AHR FRYL IRS2 PAX3

2.22e-04199725M5146
CoexpressionGSE25123_CTRL_VS_IL4_STIM_PPARG_KO_MACROPHAGE_DN

EGR1 CAST PTPRU NUP153 TREML2

2.22e-04199725M7976
CoexpressionGSE20727_H2O2_VS_ROS_INHIBITOR_TREATED_DC_UP

COL11A2 VCAN HID1 NR3C1 RUNX3

2.22e-04199725M9255
CoexpressionGSE1925_CTRL_VS_IFNG_PRIMED_MACROPHAGE_24H_IFNG_STIM_UP

IL12RB1 HOXB3 COL11A2 NFIB NR4A1

2.27e-04200725M6307
CoexpressionHALLMARK_HYPOXIA

IRS2 NR3C1 BGN MXI1 HDLBP

2.27e-04200725M5891
CoexpressionGSE17721_POLYIC_VS_GARDIQUIMOD_24H_BMDC_UP

HOXB3 SEC24B NUMB FRYL SON

2.27e-04200725M4033
CoexpressionGSE42021_CD24HI_TREG_VS_CD24HI_TCONV_THYMUS_DN

CPEB2 IGF2BP1 EGR1 NR4A1 BGN

2.27e-04200725M9616
CoexpressionGSE14350_IL2RB_KO_VS_WT_TEFF_DN

IL12RB1 VCAN RUNX3 LYST TREML2

2.27e-04200725M3424
CoexpressionGSE42088_UNINF_VS_LEISHMANIA_INF_DC_24H_UP

EGR1 VCAN CAST NR4A1 RUNX3

2.27e-04200725M9895
CoexpressionGSE29618_MONOCYTE_VS_MDC_UP

EGR1 VCAN IRS2 F5 MXI1

2.27e-04200725M4948
CoexpressionGSE42724_NAIVE_VS_MEMORY_BCELL_DN

HMBOX1 VCAN SEC24B MAPKBP1 NUP153

2.27e-04200725M9793
CoexpressionCUI_DEVELOPING_HEART_C5_VALVAR_CELL

EGR1 VCAN AHR NR4A1 BGN

2.55e-04205725M39302
CoexpressionHEVNER_CORTEX_COMMITTED_TO_SUBCEREBRAL_PROJECTION_NEURON_FATE

SCN2A LDB2

2.65e-049722MM429
CoexpressionGOZGIT_ESR1_TARGETS_DN

CPEB2 HOXB3 KANK1 DNAJA4 NR5A2 PSD3 AHR HID1 FGFR2

2.95e-04786729M10961
CoexpressionMIKKELSEN_MEF_ICP_WITH_H3K27ME3

HOXB3 MALL PRR19 INSL4 NR5A2

3.75e-04223725MM838
CoexpressionPHONG_TNF_RESPONSE_VIA_P38_COMPLETE

HMBOX1 EGR1 VCAN PSD3 NR3C1

3.83e-04224725M2500
CoexpressionTHEILGAARD_NEUTROPHIL_AT_SKIN_WOUND_DN

GTF3C1 RPS6KA5 ZNF185 NUP214 NUP153

4.07e-04227725M11234
CoexpressionSESTO_RESPONSE_TO_UV_C2

KANK1 ZNF185 NR3C1

4.46e-0454723M2589
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

IGF2BP1 RPS6KA5 EGR1 NFIB VCAN SCN2A PSD3 NUMB ZC3H12B CACHD1 FGFR2 NR4A1 MXI1

1.70e-067837113gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#2_top-relative-expression-ranked_1000

EGR1 NFIB VCAN SCN2A PSD3 NR4A1 LDB2 BGN

2.86e-06265718gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k2_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_top-relative-expression-ranked_1000

IGF2BP1 RPS6KA5 EGR1 NFIB VCAN SCN2A PSD3 ZC3H12B CACHD1 NR4A1 LDB2 BGN

1.82e-058317112gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_500

EGR1 VCAN PSD3 NR4A1 BGN

5.54e-05122715gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_500
CoexpressionAtlasdev gonad_e12.5_F_VasAssocMesStromOvary_Sma_top-relative-expression-ranked_1000

EGR1 NFIB VCAN ZNF185 PSD3 NUMB ZC3H12B CACHD1 FGFR2 NR4A1 BGN

6.37e-057977111gudmap_dev gonad_e12.5_F_VasAssocMesStromOvary_Sma_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ bladder_emap-30872_top-relative-expression-ranked_1000

IGF2BP1 NFIB VCAN NR5A2 NUP214 HUWE1 NR3C1 THSD1 PRRC1 SON HDLBP

7.44e-058117111gudmap_developingLowerUrinaryTract_e14.5_ bladder_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_top-relative-expression-ranked_1000

MAPK8IP1 IGF2BP1 GTF3C1 SEC24B DVL2 NUMB PAX3 FGFR2 AHDC1 SON HDLBP

1.05e-048437111gudmap_developingGonad_e11.5_testes_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_top-relative-expression-ranked_1000

EGR1 NFIB VCAN SCN2A PSD3 NUMB FGFR2 NR4A1 LDB2 BGN

1.68e-047407110gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_1000
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#3_top-relative-expression-ranked_1000

EGR1 NFIB VCAN SCN2A PSD3 ZC3H12B BGN

1.80e-04354717gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k3_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_emap-3087_k-means-cluster#4_top-relative-expression-ranked_100

EGR1 NR4A1

2.29e-047712gudmap_developingLowerUrinaryTract_e13.5_bladder neck-urethr mesench_100_k4
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_top-relative-expression-ranked_1000

CPEB2 RPS6KA5 NFIB VCAN SCN2A AHR HUWE1 NR3C1 ADARB2 HDLBP

2.36e-047727110gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000
CoexpressionAtlasDevelopingGonad_e11.5_testes_emap-3226_k-means-cluster#5_top-relative-expression-ranked_1000

MAPK8IP1 IGF2BP1 GTF3C1 SEC24B NUMB FGFR2 SON HDLBP

2.52e-04498718gudmap_developingGonad_e11.5_testes_k5_1000
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_top-relative-expression-ranked_1000

EGR1 NFIB VCAN SCN2A PSD3 NUMB CACHD1 FGFR2 NR4A1 BGN

3.05e-047977110gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_Sma_1000
ToppCellnormal-na-Myeloid-classical_monocyte-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

EGR1 VCAN CAST AHR IRS2 NUP214 LYST

3.32e-0819872758aa5041077fe17ca01c5e6da077d8008d5123ab
ToppCellLPS_IL1RA-Endothelial-Endothelial-Gen_Cap|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

NFIB NR5A2 AHR HID1 NIPBL LDB2 SON

3.56e-08200727dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NFIB CACHD1 FGFR2 PAX9 PTPRU ADARB2

4.29e-07177726cbad1a23851151dbef01ea2af960e6f0944f838b
ToppCellnucseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Basal|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

NFIB CACHD1 FGFR2 PAX9 PTPRU ADARB2

4.29e-07177726ce86dfaeb74d995a19aea62f0fb15c4c0bb854b0
ToppCellPCW_07-8.5-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

NFIB VCAN NR3C1 ADARB2 LDB2 BGN

5.56e-071857261ac6a32cc56d5d819649bdd99518e2ead0eead4c
ToppCell(2)_NK/T-(210)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

PWWP2A IGF2BP1 GTF3C1 CAST FGFR2 RUNX3

6.30e-07189726fa72e87e1e8cd7cbddae7b47e19cf90d181820a7
ToppCell(2)_NK/T-(21)_NKT_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

PWWP2A IGF2BP1 GTF3C1 CAST FGFR2 RUNX3

6.30e-07189726b37ad24898a14a4a3b2d6cea2637de2471f76e20
ToppCellCOVID-19-lung-Vein_EC|COVID-19 / Disease (COVID-19 only), tissue and cell type

HMBOX1 NFIB NR5A2 CACHD1 LYST LDB2

6.50e-071907261caeaef78326734c1e31a0c4739190d5c5a77b9e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KANK1 PIK3C2G MALL CACHD1 FGFR2 NR4A1

6.70e-0719172634cc997e4e5c727495f321e6807a84aa124da486
ToppCell10x5'v1-week_12-13-Endothelial-stroma-tip_EC|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

NFIB PRKAA2 NR5A2 HID1 THSD1 LDB2

6.70e-07191726cf1a67b7c0d5c0dc5d4d59faf9d9b1a3a1fb00e0
ToppCellControl-Epithelial-Club|Control / Disease state, Lineage and Cell class

MALL NFIB AHR CACHD1 FGFR2 PTPRU

6.90e-07192726d84ed1ea4a03edaa18c804f75afb03bd7b1f0e16
ToppCellIPF-Epithelial-Basal|World / Disease state, Lineage and Cell class

KANK1 NFIB CACHD1 FGFR2 PAX9 PTPRU

6.90e-071927269b91e0b162e6f3ce86dd15cc33c2e745d069581f
ToppCellLPS-antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NR5A2 CACHD1 THSD1 LDB2

7.12e-071937266e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCellfacs-Skin-Anagen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK8IP1 KANK1 DNAJA4 NFIB THSD1 BGN

7.12e-07193726eba3c70701b051bc1ed1f4db9270cb27a77ffc3e
ToppCellLPS_only-Endothelial-Endothelial-Gen_Cap|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NR5A2 CACHD1 THSD1 LDB2

7.12e-07193726af5108260783e69a7d67896c5bf64f862525926d
ToppCellfacs-Skin-Anagen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAPK8IP1 KANK1 DNAJA4 NFIB THSD1 BGN

7.34e-071947265d30d3d41d5f19cdf3077cc609aa2738762cb8c5
ToppCellControl-Epithelial|Control / Disease state, Lineage and Cell class

KANK1 MALL NFIB AHR CACHD1 FGFR2

7.56e-071957261798c3b89b1b5ff4f5777d2b9f52dc81cdad28fa
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area|World / Primary Cells by Cluster

NFIB VCAN SCN2A PSD3 PTPRU LDB2

8.02e-0719772679b9e7f2e8e33b3c547f716be5667156c48b0dfc
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Layer_VI_Pan-area-33|World / Primary Cells by Cluster

NFIB VCAN SCN2A PSD3 PTPRU LDB2

8.02e-07197726d20f29088e9afd8a960d6f680075c380e550f8a7
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c3-CD14-VCAN|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EGR1 VCAN IRS2 NUP214 F5 LYST

8.02e-0719772615bcfe6105c0b508811fb9bba0bc4312fea04f4c
ToppCellsevere-HLA-DR+_CD83+_Monocyte|severe / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EGR1 MUC17 VCAN AHR NUMB LYST

8.26e-07198726a77f3440d7fb6a50066abc7e9ad59e83798ef13d
ToppCellsevere-HLA-DR+_CD83+_Monocyte|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

EGR1 MUC17 VCAN AHR NUMB LYST

8.26e-07198726d5e525d2f2226d06a3fb985ce3a33555ff4b2e7b
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial|6m / Sample Type, Dataset, Time_group, and Cell type.

EGR1 VCAN CAST NR4A1 NR3C1 BGN

8.76e-072007262cc98abf11f5b58707de45a2282f03d47f00f035
ToppCellBronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Mucous|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PRKAA2 PSD3 IRS2 HID1 PAX9 ADARB2

8.76e-07200726ed093626a9cac7531a2bf02f6e345c5e84b8c060
ToppCellBrain_organoid-organoid_Tanaka_cellReport-6m-Neuroepithelial-Proteoglycan-expressing_cell|6m / Sample Type, Dataset, Time_group, and Cell type.

EGR1 VCAN CAST NR4A1 NR3C1 BGN

8.76e-072007260f7431f670f3a175377cefae3479403a881bb8fb
ToppCellCOVID-19_Convalescent-Classical_Monocyte|COVID-19_Convalescent / Disease condition and Cell class

EGR1 VCAN AHR NUP214

5.71e-067272473db21be480920fc936f3a965495f5cf004e350a
ToppCellTCGA-Uterus-Primary_Tumor-Uterine_Carcinoma-Uterine_Carcinosarcoma-3|TCGA-Uterus / Sample_Type by Project: Shred V9

CPEB2 RPS6KA5 AHR FRYL LYST

6.75e-06163725d64dd39b077105c73e570ccef70f0e74a2c586ac
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LILRA1 VCAN NUP214 F5 LYST

8.28e-0617072546a81d505de845cc59f80594fce338f7fdb9250f
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LILRA1 VCAN NUP214 F5 LYST

8.28e-061707251a9a0487c35cf3fd5806d1f0f0e91ef0e0b9cd0a
ToppCell3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LILRA1 VCAN NUP214 F5 LYST

8.28e-06170725830646815410c47e9bca8c9bae75dfc45c9c9b33
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D122|Adult / Lineage, Cell type, age group and donor

PRKAA2 NR5A2 HID1 THSD1 LDB2

9.01e-06173725dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

KANK1 PIK3C2G SCN2A USP43 CACHD1

1.12e-05181725e0abf2707d9e0aa942c657eef7d2cbcd02f060dd
ToppCellfacs-Lung-Endomucin_-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 MALL ZC3H12B FRYL LDB2

1.12e-051817254ea02344e1996f264dd5e14f3b19c8782ce41699
ToppCellControl-Epithelial-Basal|World / Disease state, Lineage and Cell class

NFIB CACHD1 FGFR2 PAX9 PTPRU

1.15e-05182725759390dde9b18757f7675d13d44c89d0e32f8d93
ToppCellControl-Epithelial-Basal|Control / Disease state, Lineage and Cell class

NFIB CACHD1 FGFR2 PAX9 PTPRU

1.15e-05182725caddd0a52f0234ea6a916186ffaf2454cdcd80ee
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB2 KANK1 PIK3C2G SCN2A CACHD1

1.18e-051837252f0ee40e69ad1259e56e8ee4b352736900eb8901
ToppCellCOPD-Epithelial-Basal|COPD / Disease state, Lineage and Cell class

KANK1 NFIB CACHD1 FGFR2 PTPRU

1.18e-051837250f760e393edc91009bf6c7e02eeac039a1dfb4ed
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Granulocytic-Neutrophil-Neu_c1-IL1B|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EGR1 VCAN NUMB IRS2 F5

1.28e-0518672505c40bac5c0ade8b67b7c2112739466e02dbf22b
ToppCellSmart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

EGR1 VCAN SCN2A AHR IRS2

1.28e-0518672523b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCellControl-Epithelial-Club|World / Disease state, Lineage and Cell class

MALL NFIB AHR CACHD1 FGFR2

1.28e-051867259798428691408e17ff2af2fe2d1b345f074d67e4
ToppCellCOVID-19-Epithelial_cells-Airway_basal|COVID-19 / group, cell type (main and fine annotations)

PSD3 CACHD1 FGFR2 PAX9 ADARB2

1.31e-051877258407a82e98f56a94ea26562bcb6bbe00a8f41661
ToppCellfacs-Heart-RA-3m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 MALL HID1 FGFR2 PTPRU

1.35e-051887254ddb11a90bf3baa7237bde304db44dfcc56aed52
ToppCellfacs-Heart-RA-3m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 MALL HID1 FGFR2 PTPRU

1.35e-05188725e47e66906922d5c69b1aafe28face0787d3fc563
ToppCellChildren_(3_yrs)-Endothelial-capillary_endothelial_cell_(Cap1)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NFIB NR5A2 FRYL THSD1 LDB2

1.35e-05188725117dc80fa940e6aa1b0187a43fdde33f3fcb578f
ToppCelldroplet-Tongue-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EGR1 NFIB AHR NIPBL SON

1.35e-05188725d62cc37e86b7b186e53aeb7f421c4e5ee28f23bd
ToppCellE16.5-samps-Mesenchymal|E16.5-samps / Age Group, Lineage, Cell class and subclass

HOXB3 NFIB VCAN NR3C1 BGN

1.35e-051887253f0f662be684e3a4c6652e636cc135a39a1d2790
ToppCellCOPD-Epithelial-ATII|COPD / Disease state, Lineage and Cell class

KANK1 MALL AHR CACHD1 FGFR2

1.35e-05188725eb6d79d733b53f64ca615bb777c64ed456866549
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB2 KANK1 PIK3C2G SCN2A USP43

1.38e-05189725977a813e5d7a5a561c1fced2bbf21c20056b88d8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HOXB3 KANK1 PIK3C2G SCN2A CACHD1

1.38e-05189725975c0f079903ae36b0ffa54e86294d42ec7697de
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

HOXB3 KANK1 PIK3C2G SCN2A CACHD1

1.38e-051897257eb8f5a951e80f1cfac4d7c9eb169f4eb100c917
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KANK1 MALL CACHD1 FGFR2 NR4A1

1.42e-051907258aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellIPF-Epithelial-Basal|IPF / Disease state, Lineage and Cell class

KANK1 CACHD1 FGFR2 PAX9 PTPRU

1.42e-05190725ea19e9ce954f2dfde97388db9695325cd92ab88f
ToppCellControl-Epithelial-ATII|Control / Disease state, Lineage and Cell class

KANK1 MALL AHR CACHD1 FGFR2

1.42e-05190725d50902a3abcc18aafa36d83cc2c6e07d7f7cb197
ToppCell3'-Broncho-tracheal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LILRA1 VCAN NUP214 F5 LYST

1.45e-051917255d6ef70cc15ec5e983a953e547e40f9c06e355fb
ToppCell10x5'v1-week_17-19-Endothelial-stroma-proliferating_EC|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

MALL NFIB NR5A2 BSN LDB2

1.45e-05191725dc9e5eb6aa31b8d79aeec33e59b9138dfb469a3b
ToppCell390C-Myeloid-Mast_cell-|390C / Donor, Lineage, Cell class and subclass (all cells)

RPS6KA5 EGR1 DNAJA4 AHR NR4A1

1.45e-0519172588bcd0b85b2112cef15c9e44d1429f9fba4a3400
ToppCell390C-Myeloid-Mast_cell|390C / Donor, Lineage, Cell class and subclass (all cells)

RPS6KA5 EGR1 DNAJA4 AHR NR4A1

1.45e-05191725c1517ea7b10a7f732725b4c0224fbfecae80d18b
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_chondroblast_(18)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

COL11A2 RPS6KA5 NFIB FGFR2 LDB2

1.49e-05192725d0649410cf5eacdb0c1dce70e37c7473ef5fddfa
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

EGR1 NFIB VCAN NR4A1 BGN

1.49e-051927258171a60df481195c39a7f740effcae8e4deb6ca7
ToppCell367C-Myeloid-Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 DNAJA4 VCAN IRS2 NR4A1

1.49e-0519272526326d7c3d907d754e85e128b7d8a52e90863f3f
ToppCellCOPD-Epithelial-Goblet|COPD / Disease state, Lineage and Cell class

MALL PRKAA2 FGFR2 PAX9 PTPRU

1.49e-0519272593b2ca0a97776d28c7e8f1a0642c4b63a5554aab
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

KANK1 PIK3C2G MALL CACHD1 FGFR2

1.49e-05192725fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellLPS-IL1RA+antiTNF-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NR5A2 THSD1 LDB2

1.53e-05193725e09387af84d2a0a526e54d4793e6e06c6739db53
ToppCell10x5'-Lung-Myeloid_Monocytic|Lung / Manually curated celltypes from each tissue

LILRA1 VCAN NUP214 F5 LYST

1.53e-05193725ebe6be10ef5de9e1da988e263106698d3db42fce
ToppCelldroplet-Bladder-nan-3m|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EGR1 NFIB VCAN NR4A1 BGN

1.53e-05193725e55f79bad6888b84b0ad5fccded498b170e3c6dc
ToppCellControl-Endothelial-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NUMB THSD1 LDB2

1.53e-05193725aff0649c73c634bc6ff0dc7759b4693a9236bf05
ToppCellControl-Endothelial|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NUMB THSD1 LDB2

1.53e-05193725c5f9fe03e64c211d4bcd4959e5b32f14841e336a
ToppCellControl-Endothelial-Endothelial-Gen_Cap|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NR5A2 THSD1 LDB2

1.53e-05193725e1d546165dcc2392f540162206852c4717d7306f
ToppCell367C-Myeloid-Monocyte-CD14+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 DNAJA4 VCAN IRS2 NR4A1

1.53e-05193725c7ecd98729419b34c14f9b387b15472c47951d2f
ToppCell10x5'-GI_small-bowel|World / Manually curated celltypes from each tissue

EGR1 MUC17 DNAJA4 AHR NR4A1

1.53e-05193725cd89dfe53a114078f06343049685883c8e26508f
ToppCelldroplet-Tongue-nan-3m-Epithelial|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EGR1 NFIB PAX9 NR4A1 NIPBL

1.53e-0519372507ddb9525b686c31fa7df4286557d1e58f7ead52
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Reg4/cKit+_deep_crypt_secretory_cells_(Distal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJA4 A4GNT HID1 NR4A1 PRRC1

1.57e-051947250797245ebfa389a6f66874cb0f11297f1456e600
ToppCellControl-Classical_Monocyte|Control / Disease condition and Cell class

EGR1 VCAN IRS2 NUP214 F5

1.57e-051947259e33e1b54b4114f9e6981819834bb796ed7192b5
ToppCelltumor_Lung|World / Location, Cell class and cell subclass

EGR1 AHR NR4A1 NR3C1 BGN

1.57e-051947257e6b8a30f8d08252ad3f1df826d6f7c0ba997c2c
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VCAN IRS2 NUP214 F5 LYST

1.57e-05194725e2d0dfb92356fa7ad7008aa8ac4198e2ac5d2495
ToppCelldroplet-Bladder-nan-3m-Epithelial|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EGR1 NFIB VCAN NR4A1 BGN

1.57e-05194725b294056f9bdc243263cf36dce7b62564144b9de1
ToppCellLPS-IL1RA-Endothelial-Endothelial-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

HMBOX1 NFIB NR5A2 CACHD1 LDB2

1.57e-051947250b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-secretory_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJA4 A4GNT HID1 NR4A1 PRRC1

1.57e-051947250241b4b88d6210b4c1b8aa99db17115b18142f01
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VCAN PSD3 ADARB2 LDB2 BGN

1.61e-05195725d9a5c75d31c6e8bb1e1ab7fd115ac5deb5fb1c8d
ToppCell367C-Myeloid-Monocyte-CD14+_Monocyte|367C / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 DNAJA4 VCAN IRS2 NUP214

1.61e-051957254f9e26e033353fc9a8bdbd10358ee68ab2291880
ToppCelldistal-Hematologic-Classical_Monocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LILRA1 VCAN IRS2 NUP214 F5

1.61e-0519572532c34741e35006b7238896fd04a497011297dd22
ToppCell11.5-Distal-Endothelial|Distal / Age, Tissue, Lineage and Cell class

NR5A2 AHR HID1 THSD1 LDB2

1.61e-05195725efdede0f476883ffddd247fa7bc6449e7932613e
ToppCell11.5-Distal-Endothelial-Endothelial|Distal / Age, Tissue, Lineage and Cell class

NR5A2 AHR HID1 THSD1 LDB2

1.61e-051957251e9b52b201ab6c78f536609e2afe1d680c71a6e7
ToppCellmetastatic_Brain-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

EGR1 MALL NFIB PAX9 NR4A1

1.61e-0519572598a21f5e27d98384b3086034bd6f83441e2e4ef9
ToppCellsevere-Classical_Monocyte|World / disease stage, cell group and cell class

EGR1 VCAN AHR IRS2 NUP214

1.61e-05195725cf638aac4d57ae0774008920a1a5e9dfd8c73885
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Monocytes|Myeloid_cells / Location, Cell class and cell subclass

LILRA1 VCAN IRS2 NUP214 LYST

1.61e-051957258861c82129f3ef241b1e9fa4825e4621550cee96
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPEB2 KANK1 PIK3C2G SCN2A CACHD1

1.61e-05195725a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCellP03-Mesenchymal|P03 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

EGR1 NFIB VCAN NR4A1 BGN

1.61e-051957256180309c6ae278b996fd98c57461cbc129c028ba
ToppCell343B-Myeloid-Monocyte-CD14+_Monocyte|343B / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 VCAN NUP214 NR4A1 F5

1.61e-05195725b5ee368c97113432fc8fe742654cd538558f327c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VCAN PSD3 ADARB2 LDB2 BGN

1.65e-05196725a12dd986df65c36f248cf10815c3b8b6238613b0
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Myeloid-Monocytic-Classical_Monocyte-Mono_c1-CD14-CCL3|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

EGR1 VCAN AHR IRS2 LYST

1.65e-051967251d170422a9eb5e477ce837f9da1c7db95ee5da1c
ToppCellfacs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 NFIB ZNF185 NR3C1 THSD1

1.65e-0519672590edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell10x5'v1-week_17-19-Myeloid_neutrophil-granulo-neutrophil|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

VCAN IRS2 NUP214 F5 LYST

1.65e-05196725ad193b231ff2f7c72590fab79919c179d5d2f327
ToppCellE17.5-Mesenchymal-mesenchymal_fibroblast-mesenchymal_progenitor_cell|E17.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

HOXB3 EGR1 NFIB VCAN BGN

1.65e-05196725028a06ed92f1c058dcbeacd335625bf529e87a7b
ToppCellfacs-Skin-Telogen-3m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KANK1 NFIB ZNF185 NR3C1 THSD1

1.65e-05196725c936014125b2ed5f796221b74acb77b8f8359875
ToppCell367C-Myeloid-Monocyte|367C / Donor, Lineage, Cell class and subclass (all cells)

LILRA1 DNAJA4 VCAN IRS2 NUP214

1.65e-05196725202066aeb837659fcc2e127fb52d7189e2e3520d
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VCAN PSD3 ADARB2 LDB2 BGN

1.65e-051967253e6803587d8566fd08cb8b290be3b6461743d79c
ToppCellsevere_COVID-19-Classical_Monocyte|World / disease group, cell group and cell class (v2)

EGR1 VCAN IRS2 NUP214 F5

1.69e-05197725cdffd49db7374d223ded46d636cd4be12d464ea4
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Fibroblast|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

VCAN PSD3 ADARB2 LDB2 BGN

1.69e-051977256d027119a5f7ca2aac1b10837e43f9a2bb54db85
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

EGR1 PIK3C2G MALL CACHD1 NR4A1

1.69e-05197725fd7bdfa6bf5966ebc11fdd13915769429540ddbf
DrugUrsolic acid [77-52-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

EGR1 MALL FUBP1 PSD3 IRS2 NR4A1 LYST

1.94e-061827372230_UP
DrugDicyclomine hydrochloride [67-92-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 IRS2 FGFR2 NR4A1 NR3C1 THSD1

2.58e-061907371483_UP
DrugHexestrol [84-16-2]; Up 200; 14.8uM; MCF7; HT_HG-U133A

EGR1 INSL4 NR5A2 NUP214 NR4A1 NR3C1 BGN

2.67e-061917376077_UP
DrugAcetylsalicylsalicylic acid [530-75-6]; Up 200; 13.4uM; MCF7; HT_HG-U133A

MALL NFIB INSL4 PSD3 NUP214 NR4A1 LYST

2.96e-061947372223_UP
DrugAcyclovir [59277-89-3]; Down 200; 17.8uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 DNAJA4 FGFR2 NIPBL NUP153 HDLBP

3.17e-061967371543_DN
DrugConvolamine hydrochloride [500-56-1]; Down 200; 11.8uM; MCF7; HT_HG-U133A

IL12RB1 DVL2 PSD3 IRS2 FGFR2 PTPRU AHDC1

3.39e-061987372771_DN
DrugKetoprofen [22071-15-4]; Up 200; 15.8uM; MCF7; HT_HG-U133A

EGR1 MALL PSD3 A4GNT PAX9 THSD1 BSN

3.39e-061987372316_UP
DrugPhenytoin

EGR1 VCAN SCN2A AHR PAX3 FGFR2 NR3C1 NUP153 LDB2

3.85e-06385739ctd:D010672
Drugheparin-sepharose

AHR NR3C1

1.01e-052732ctd:C037405
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA

EGR1 DVL2 AHR IRS2 NR4A1 THSD1

1.10e-051567361010_UP
DrugDigoxin [20830-75-5]; Up 200; 5.2uM; MCF7; HT_HG-U133A

EGR1 NFIB IRS2 HUWE1 NR4A1 NR3C1

1.56e-051667363283_UP
DrugPerhexiline maleate [6724-53-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 IRS2 NR4A1 NR3C1 ARHGEF11

1.78e-051707365501_UP
Drugwortmannin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

RPS6KA5 EGR1 FRYL IRS2 THSD1 MXI1

2.04e-05174736977_UP
Drugwortmannin; Up 200; 1uM; MCF7; HT_HG-U133A_EA

RPS6KA5 EGR1 FRYL IRS2 THSD1 MXI1

2.10e-05175736869_UP
DrugFelodipine [72509-76-3]; Up 200; 10.4uM; MCF7; HT_HG-U133A

EGR1 DVL2 IRS2 NUP214 NR4A1 BGN

2.10e-051757363295_UP
DrugThioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; MCF7; HT_HG-U133A

EGR1 MALL IRS2 NR4A1 F5 BGN

2.24e-051777364164_UP
DrugAC1L1D59

PIKFYVE RPS6KA5 EGR1 PIK3C2G AHR IRS2 NR4A1

2.32e-05266737CID000002199
Drugtrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 AHR THSD1 LYST MXI1

2.46e-051807366579_UP
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 NFIB IRS2 NR3C1 MXI1

2.88e-051857366945_UP
DrugForskolin, from Coleus forskohlii; Up 200; 0.5uM; MCF7; HT_HG-U133A

PSD3 IRS2 FGFR2 NR4A1 NR3C1 AHDC1

2.88e-051857367055_UP
DrugBetulinic acid [472-15-1]; Up 200; 8.8uM; MCF7; HT_HG-U133A

EGR1 DNAJA4 MALL IRS2 PTPRU ARHGEF11

3.15e-051887363281_UP
DrugMebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A

EGR1 MALL NR5A2 A4GNT IRS2 F5

3.24e-051897362300_UP
Drug17-AAG; Down 200; 1uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 PTPRU MAPKBP1 THSD1 AHDC1

3.24e-051897365578_DN
Druggeldanamycin; Up 200; 1uM; MCF7; HG-U133A

INSL4 FGFR2 NR4A1 NR3C1 NIPBL HDLBP

3.24e-05189736611_UP
Drugtrichostatin A; Up 200; 0.1uM; MCF7; HG-U133A

RPS6KA5 AHR NR4A1 F5 TREML2 MXI1

3.34e-05190736331_UP
DrugClomipramine hydrochloride [17321-77-6]; Up 200; 11.4uM; MCF7; HT_HG-U133A

EGR1 MALL NFIB IRS2 NR4A1 BGN

3.34e-051907366825_UP
DrugNaringenine [480-41-1]; Up 200; 14.6uM; HL60; HT_HG-U133A

EGR1 VCAN AHR NR4A1 NIPBL HDLBP

3.34e-051907361342_UP
DrugDimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; MCF7; HT_HG-U133A

EGR1 MALL NR5A2 PSD3 IRS2 NR4A1

3.44e-051917364791_UP
Drugradicicol, diheterospora chlamydosporia; Up 200; 0.1uM; MCF7; HT_HG-U133A

EGR1 NUP214 FGFR2 NR3C1 RUNX3 BGN

3.54e-051927365216_UP
Drugestradiol; Up 200; 0.01uM; MCF7; HT_HG-U133A

NFIB DVL2 FGFR2 NR4A1 NR3C1 ARHGEF11

3.54e-051927365955_UP
Drugreverse T

MAPK8IP1 AHR F5 BGN

3.62e-0558734CID000064973
DrugMEK1/2 inhibitor

PIKFYVE RPS6KA5 EGR1 PIK3C2G AHR NR4A1

3.65e-05193736CID009549284
DrugAmoxapine [14028-44-5]; Up 200; 12.8uM; MCF7; HT_HG-U133A

EGR1 NR5A2 IRS2 MAPKBP1 THSD1 BGN

3.65e-051937364996_UP
DrugAntazoline hydrochloride [2508-72-7]; Up 200; 13.2uM; MCF7; HT_HG-U133A

SCN2A INSL4 PSD3 ARHGEF11 F5 LDB2

3.75e-051947363173_UP
Drug17-AAG; Down 200; 1uM; SKMEL5; HG-U133A

EGR1 PAX3 NR4A1 NR3C1 RUNX3 NIPBL

3.86e-05195736505_DN
DrugBumetanide [28395-03-1]; Down 200; 11uM; HL60; HT_HG-U133A

DNAJA4 DVL2 NR4A1 ARHGEF11 F5 AHDC1

3.86e-051957362409_DN
DrugFendiline hydrochloride [13636-18-5]; Up 200; 11.4uM; HL60; HG-U133A

RPS6KA5 CAST NR4A1 NR3C1 PTPRU PRRC1

3.86e-051957361573_UP
DrugTrichlorfon [52-68-6]; Up 200; 15.6uM; MCF7; HT_HG-U133A

FUBP1 NR5A2 PSD3 FGFR2 HUWE1 PAX9

3.97e-051967365989_UP
DrugMethylprednisolone, 6-alpha [83-43-2]; Up 200; 10.6uM; MCF7; HT_HG-U133A

DVL2 PSD3 A4GNT IRS2 PTPRU MAPKBP1

3.97e-051967366785_UP
DrugCGX 0596987; Down 200; 20uM; MCF7; HT_HG-U133A

HOXB3 DNAJA4 HUWE1 NR3C1 ARHGEF11 LDB2

4.09e-051977366412_DN
DrugGibberellic acid [77-06-5]; Up 200; 11.6uM; MCF7; HT_HG-U133A

EGR1 NFIB VCAN INSL4 NR4A1 NR3C1

4.09e-051977364818_UP
DrugBromopride [4093-35-0]; Up 200; 11.6uM; MCF7; HT_HG-U133A

HOXB3 IRS2 PAX3 PAX9 MAPKBP1 LYST

4.09e-051977363617_UP
DrugEthisterone [434-03-7]; Up 200; 12.8uM; HL60; HT_HG-U133A

IL12RB1 EGR1 VCAN NR5A2 DVL2 FGFR2

4.09e-051977362366_UP
DrugCorynanthine hydrochloride [66634-44-4]; Up 200; 10.2uM; MCF7; HT_HG-U133A

EGR1 DNAJA4 NR4A1 NR3C1 BGN HDLBP

4.09e-051977362786_UP
DrugIoversol [87771-40-2]; Up 200; 5uM; MCF7; HT_HG-U133A

DNAJA4 MALL VCAN FGFR2 NR3C1 F5

4.09e-051977363365_UP
DrugAzaperone [1649-18-9]; Up 200; 12.2uM; MCF7; HT_HG-U133A

HOXB3 DNAJA4 NFIB NR4A1 RUNX3 LYST

4.09e-051977363573_UP
DrugMeropenem [96036-03-2]; Down 200; 10.4uM; MCF7; HT_HG-U133A

EGR1 NUMB NR4A1 MAPKBP1 NIPBL AHDC1

4.21e-051987367180_DN
Drugbutein; Down 200; 10uM; MCF7; HG-U133A

IL12RB1 MALL NFIB INSL4 NUP214 FGFR2

4.21e-05198736607_DN
DrugUrosiol [128-13-2]; Up 200; 10.2uM; MCF7; HT_HG-U133A

HOXB3 DNAJA4 PSD3 NUP214 RUNX3 BGN

4.21e-051987366484_UP
DrugPrednicarbate [73771-04-7]; Up 200; 8.2uM; MCF7; HT_HG-U133A

VCAN PSD3 IRS2 RUNX3 F5 BGN

4.33e-051997365544_UP
DrugIproniazide phosphate [305-33-9]; Up 200; 14.4uM; HL60; HG-U133A

GTF3C1 VCAN CAST A4GNT NR4A1 MAPKBP1

4.33e-051997361442_UP
DrugPyrimethamine [58-14-0]; Up 200; 16uM; MCF7; HT_HG-U133A

DNAJA4 MALL PRKAA2 IRS2 NUP214 ARHGEF11

4.45e-052007361474_UP
DrugOxantel pamoate [68813-55-8]; Up 200; 6.6uM; MCF7; HT_HG-U133A

RPS6KA5 INSL4 IRS2 NUP214 PTPRU MAPKBP1

4.45e-052007362632_UP
DrugTelenzepine dihydrochloride [147416-96-4]; Up 200; 9uM; MCF7; HT_HG-U133A

HOXB3 EGR1 CAST THSD1 LYST BGN

4.45e-052007365521_UP
Drugfluocinolone

MAPK8IP1 NR3C1

6.06e-054732CID000091488
Drug4,7-phenanthroline

AHR NR3C1

6.06e-054732CID000067472
Drug4-S-UTP

ERVK-6 GTF3C1

6.06e-054732CID003033941
DrugSL 327

RPS6KA5 EGR1 AHR

6.91e-0525733ctd:C424127
Drug3-O-methyl-D-glucose

PIKFYVE PIK3C2G IRS2 ADARB2

8.48e-0572734CID000008973
DrugAC1L9K70

EGR1 HGS NR5A2 NR3C1 NIPBL AHDC1

9.18e-05228736CID000446871
Drugaurin

EGR1 AHR NR3C1

9.78e-0528733ctd:C017037
DrugHCDF

AHR NR3C1

1.01e-045732CID000051130
Drugfipexide

HGS F5

1.01e-045732CID000003351
DrugGF109203X

PIKFYVE RPS6KA5 EGR1 PIK3C2G NUP214 NR4A1 NR3C1

1.11e-04341737CID000002396
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A_EA

EGR1 AHR IRS2 FGFR2 NR4A1

1.42e-041557351068_UP
DrugSuloctidil [54063-56-8]; Up 200; 11.8uM; MCF7; HT_HG-U133A

EGR1 VCAN PSD3 IRS2 NR4A1

1.51e-041577352651_UP
Drug1,2,3,4,7,8-hexachlorodibenzofuran

AHR NR3C1

1.51e-046732ctd:C051412
Drug2,6-di-tert-butyl-4-hydroxy-4-methyl-2,5-cyclohexadien-1-one

AHR NR3C1

1.51e-046732ctd:C038639
Drug18-VP

NR4A1 NR3C1

1.51e-046732CID000133557
Drug18EP

NR4A1 NR3C1

1.51e-046732CID003082761
DrugSP600125

PIKFYVE MAPK8IP1 RPS6KA5 EGR1 PIK3C2G AHR FGFR2

1.60e-04362737CID000008515
DrugAC1L1AWH

EGR1 HGS LYST

1.61e-0433733CID000001178
DrugPyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; MCF7; HT_HG-U133A

EGR1 AHR IRS2 FGFR2 NR3C1

1.69e-041617355439_UP
DrugON 01910

EGR1 NFIB FGFR2 NR3C1 MXI1

1.74e-04162735ctd:C507134
DrugThioridazine hydrochloride [130-61-0]; Up 200; 9.8uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 IRS2 NR4A1 MAPKBP1

1.74e-041627351486_UP
Drugthioridazine hydrochloride; Up 200; 10uM; MCF7; HT_HG-U133A

EGR1 IRS2 NR4A1 NR3C1 LYST

1.74e-041627351655_UP
DrugLanatoside C [17575-22-3]; Up 200; 4uM; MCF7; HT_HG-U133A

EGR1 IRS2 NR4A1 NR3C1 SON

1.85e-041647353852_UP
DrugPyrvinium pamoate [3546-41-6]; Up 200; 3.4uM; MCF7; HT_HG-U133A

EGR1 PSD3 AHR IRS2 NR3C1

1.95e-041667353518_UP
DrugHelveticoside [630-64-8]; Up 200; 7.4uM; MCF7; HT_HG-U133A

EGR1 VCAN IRS2 NR4A1 NR3C1

2.01e-041677356047_UP
DrugSistan

ERVK-6 VCAN ZNF185

2.09e-0436733CID003001858
Drugdrotaverine HCl

NUMB NR3C1

2.11e-047732CID000026394
DrugTolterodine Tartrate

AHR NR3C1

2.11e-047732ctd:D000068737
DrugMT-19

EGR1 NR4A1

2.11e-047732CID003083507
Drugcelastrol; Up 200; 2.5uM; MCF7; HT_HG-U133A_EA

EGR1 DNAJA4 IRS2 NR4A1 NR3C1

2.24e-04171735887_UP
DrugBisacodyl [603-50-9]; Up 200; 11uM; MCF7; HT_HG-U133A

EGR1 DNAJA4 INSL4 IRS2 NR3C1

2.24e-041717353297_UP
DrugTrichostatin A, Streptomyces sp.; Up 200; 1uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 THSD1 LYST MXI1

2.37e-041737351659_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

RPS6KA5 IRS2 THSD1 LYST MXI1

2.37e-041737355308_UP
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

RPS6KA5 EGR1 IRS2 THSD1 MXI1

2.37e-041737351016_UP
DrugPhenoxybenzamine hydrochloride [63-92-3]; Up 200; 11.8uM; MCF7; HT_HG-U133A

EGR1 MALL IRS2 NR3C1 THSD1

2.37e-041737356451_UP
DrugThonzonium bromide [553-08-2]; Up 200; 6.8uM; PC3; HT_HG-U133A

EGR1 IRS2 NR4A1 NR3C1 BGN

2.37e-041737354617_UP
Drugirinotecan HCl; Down 200; 100uM; MCF7; HT_HG-U133A

HMBOX1 NFIB NUMB FRYL NIPBL

2.43e-041747357530_DN
DrugLY 294002; Up 200; 10uM; MCF7; HT_HG-U133A_EA

RPS6KA5 EGR1 IRS2 LYST MXI1

2.43e-041747351019_UP
Drug2,6-dihydroxybenzoic acid

EGR1 NFIB HGS NR4A1 NR3C1

2.49e-04175735CID000009338
DrugIL-1R antagonist

HUWE1 LYST BGN MXI1

2.59e-0496734CID010447660
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

AHR IRS2 FGFR2 THSD1 LYST

2.63e-041777355745_UP
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

RPS6KA5 EGR1 THSD1 LYST MXI1

2.63e-041777354821_UP
Drugbeta-hydroxyasparagine

SCN2A AHR F5

2.66e-0439733CID000152191
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; PC3; HT_HG-U133A

HOXB3 IRS2 FGFR2 NR4A1 THSD1

2.70e-041787354483_UP
Drug1,7-phenanthroline

AHR NR3C1

2.80e-048732ctd:C053486
DrugC05475

HGS NR3C1

2.80e-048732CID000440696
DiseaseInsulin Resistance

PRKAA2 AHR IRS2 NR4A1

1.36e-0560714C0021655
DiseaseInsulin Sensitivity

PRKAA2 AHR IRS2 NR4A1

1.36e-0560714C0920563
Diseaseprostate cancer (implicated_via_orthology)

PAX3 FGFR2 HDLBP

6.92e-0533713DOID:10283 (implicated_via_orthology)
DiseaseC-reactive protein measurement

IL12RB1 IGF2BP1 NFIB CAST PSD3 NUMB IRS2 CACHD1 HID1 BSN HDLBP

1.37e-0412067111EFO_0004458
Disease1-methylxanthine measurement

PSD3 AHR

3.10e-0411712EFO_0021174
DiseaseSpina Bifida

PAX3 FGFR2

3.71e-0412712C0080178
DiseaseStatus Dysraphicus

PAX3 FGFR2

3.71e-0412712C0038219
DiseaseRachischisis

PAX3 FGFR2

3.71e-0412712C0266508
Diseaseadverse effect, response to xenobiotic stimulus

NFIB RUNX3 ADARB2

3.94e-0459713EFO_0009658, GO_0009410
DiseaseBrain Ischemia

IL12RB1 EGR1 F5

4.14e-0460713C0007786
DiseaseCerebral Ischemia

IL12RB1 EGR1 F5

4.14e-0460713C0917798
Diseasecystatin C measurement

IGF2BP1 NFIB AHR BSN RUNX3 ADARB2

4.18e-04402716EFO_0004617
Diseaseovary epithelial cancer (is_marker_for)

FUBP1 RUNX3

4.38e-0413712DOID:2152 (is_marker_for)
DiseaseT-cell surface glycoprotein CD3 epsilon chain measurement

PIKFYVE F5

4.38e-0413712EFO_0802114
DiseaseCraniofacial Abnormalities

COL11A2 PAX3 FGFR2 NIPBL

5.55e-04156714C0376634
Diseaseplatelet storage pool deficiency (implicated_via_orthology)

HPS5 LYST

5.87e-0415712DOID:2223 (implicated_via_orthology)
DiseaseLimb Deformities, Congenital

COL11A2 FGFR2

7.58e-0417712C0206762
Diseasetype 2 diabetes mellitus (is_implicated_in)

MAPK8IP1 PIK3C2G PRKAA2 IRS2

7.82e-04171714DOID:9352 (is_implicated_in)
DiseaseFebrile seizure (within the age range of 3 months to 6 years)

SCN2A BSN

8.52e-0418712HP_0002373
Diseasesquamous cell carcinoma (is_marker_for)

EGR1 FGFR2

9.51e-0419712DOID:1749 (is_marker_for)
Diseaselongitudinal BMI measurement

PIK3C2G CAST PSD3

1.03e-0382713EFO_0005937
Diseasenumber of teeth measurement

IGF2BP1 PAX9

1.05e-0320712EFO_0010073
Diseaseportal hypertension (biomarker_via_orthology)

FGFR2 F5

1.28e-0322712DOID:10762 (biomarker_via_orthology)
Diseasefemoral neck bone mineral density

KANK1 RPS6KA5 NFIB FUBP3

1.30e-03196714EFO_0007785
DiseaseDyslipidemias

NR5A2 AHR

1.52e-0324712C0242339
DiseaseDyslipoproteinemias

NR5A2 AHR

1.52e-0324712C0598784
DiseaseImpaired glucose tolerance

PRKAA2 NR5A2

1.65e-0325712C0271650
Diseaseprimary biliary cholangitis (is_marker_for)

IL12RB1 NR3C1

1.65e-0325712DOID:12236 (is_marker_for)
Diseasemigraine disorder

HOXB3 KANK1 NFIB NR3C1 ADARB2

1.71e-03357715MONDO_0005277
DiseaseAdenoid Cystic Carcinoma

NFIB VCAN SON

1.83e-03100713C0010606
DiseasePancreatic Neoplasm

NR5A2 AHR NR4A1

1.83e-03100713C0030297
DiseaseMalignant neoplasm of pancreas

NR5A2 AHR NR4A1

1.93e-03102713C0346647
DiseaseLiver Cirrhosis

AHR FGFR2 F5

1.99e-03103713C0023890
DiseaseTYPE 2 DIABETES MELLITUS

MAPK8IP1 IRS2

2.07e-0328712125853
DiseaseType 2 diabetes mellitus

MAPK8IP1 IRS2

2.07e-0328712cv:C0011860
DiseaseFibrosis, Liver

AHR FGFR2 F5

2.10e-03105713C0239946
Diseaseglucose measurement

MAPK8IP1 PIK3C2G CAST PSD3 BSN

2.24e-03380715EFO_0004468

Protein segments in the cluster

PeptideGeneStartEntry
MGSFEPSPYPTTSSL

AHR

721

P35869
FSTMPTLPPSYNTSE

VCAN

46

P13611
PDVMEGSNPPYYTDT

VCAN

2796

P13611
YLASSPPSGSFMDDS

PRKAA2

341

P54646
TDSTPMPSNSTYPAF

A4GNT

91

Q9UNA3
FYVSMPSGPPDSSTD

ARHGEF11

1361

O15085
GYSTMSPQEDSENPP

CACHD1

1196

Q5VU97
GSGSPSFSSPMDIFD

DNAJA4

76

Q8WW22
PYSMNPSTPSDGTFG

AHDC1

1346

Q5TGY3
LTGTFPAYPGSSSMS

DVL2

386

O14641
MEPSPTGDFYPSPSS

NFIB

281

O00712
TPSPGDTPSMYCEAK

ADARB2

686

Q9NS39
PPTNSSFSSDFMPKE

PIK3C2G

176

O75747
GESYSMPTAFPGLAP

NR4A1

221

P22736
SSGDDSVFSPDPMPY

FGFR2

791

P21802
GSFVSASSMAPYPTP

PAX9

266

P55771
MASPDPPATSYAPSD

MALL

1

Q13021
MADYSTVPPPSSGSA

FUBP1

1

Q96AE4
RMSVSSDPDPAAYPS

MAPK8IP1

306

Q9UQF2
PPSSVTGAAPYSSFM

IGF2BP1

386

Q9NZI8
DAPPSTSTMDDEGYP

HPS5

931

Q9UPZ3
AYATTAPMTPESSGP

KIAA1614

746

Q5VZ46
MSSTPHDPFYSSPFG

LDB2

1

O43679
PTFMSLYSPTETPSG

BSN

1156

Q9UPA5
SPVVPMSSAPSETSY

BSN

3166

Q9UPA5
MSSAPSETSYSGPAV

BSN

3171

Q9UPA5
ISDPFGSFPHSPTMD

EGR1

16

P18146
GMSPSPSNSYDTSPQ

HMBOX1

96

Q6NT76
SELSYAPMTPDHFPS

PDPR

636

Q8NCN5
DPDSVTPTYSAMCPF

BGN

51

P21810
SMTFGSPEFSSPEDT

FAM214A

426

Q32MH5
DFIPDYQPSPMTDSG

FRYL

1696

O94915
ASAAPQASSPPDYTM

FUBP3

531

Q96I24
PSDSDMEDYSPPPSL

NIPBL

1151

Q6KC79
EPPYYDVMTTGTTPD

COL11A2

276

P13942
TGTPPFMASPLSEMY

PLK5

6

Q496M5
DYGSYAPAAPTTSSM

KANK1

221

Q14678
NPATPSTAMGSSVPY

NUP214

1131

P35658
NGYSSPSMRPDVSSP

NR3C1

391

P04150
EFTEMDPTYSPAALP

RPS6KA5

351

O75582
SYCPMPEKTFTTTPG

INSL4

41

Q14641
DGTPMPDSYPTTPSS

HUWE1

2736

Q7Z6Z7
NISAPSFDYADMPSP

PTPRU

586

Q92729
YTDSFVPPSGPSNPM

PAX3

366

P23760
SPSDPGFMSLDEYGS

IRS2

491

Q9Y4H2
SGSPMVPSYETSVSP

PIKFYVE

316

Q9Y2I7
PDSENGFYPGLPSSM

CPEB2

6

Q7Z5Q1
SMTPSYESPSPPAFG

HOXB3

281

P14651
TYTGPEVSDPMSSTY

CAST

176

P20810
MVISPSGFTASPYEG

LYST

2071

Q99698
TAPQDPDPAGMATYS

IL12RB1

386

P42701
YPEPSDNPTMDTSEF

MAPKBP1

956

O60336
GGSYPDMLSSSASSP

SEC24B

411

O95487
SPTPAEGTSMPTSTY

MUC17

846

Q685J3
SPTPAEGTSMPTSTY

MUC17

1671

Q685J3
SPTTADGTSMPTPAY

MUC17

1966

Q685J3
PTPAYSEGSTPLTSM

MUC17

1976

Q685J3
SPTPAEGTSMPISTY

MUC17

3086

Q685J3
TSTPSEGSTPLTYMP

MUC17

3156

Q685J3
SPPIADGTSMPTSTY

MUC17

3321

Q685J3
NAFSTPEDPFSSAPM

NUMB

336

P49757
SEYPDPYTSSPESIM

NR5A2

271

O00482
PGAMSAAFPYSATPS

RUNX3

271

Q13761
SESFDFPPGSMHAPS

PWWP2A

601

Q96N64
SYSMCSDPSTRDPPG

TREML2

296

Q5T2D2
SFPYPDLGQMPSPSS

F5

1481

P12259
EFPMSPVTSAHSGTY

LILRA1

381

O75019
SEAMYLPPAPESGST

HID1

216

Q8IV36
SSMESFPPLAYSTPQ

PRRC1

46

Q96M27
SPPSPYMGFSGNSKD

USP43

966

Q70EL4
EFTFPMPYTSSMPTA

PRR19

236

A6NJB7
FTMTPEATDNSTPFP

THSD1

101

Q9NS62
AGPYPSMPSTAADPS

HGS

616

O14964
EKTDMTPSTTSPPSY

SCN2A

1961

Q99250
GAEITMPAPSYSPTS

ERVK-6

101

Q9Y6I0
SPSSTGSPMFKFSSP

NUP153

516

P49790
PSTGTRSSCPADYPM

ZC3H12B

666

Q5HYM0
APDMSSSEEFPSFGA

HDLBP

1241

Q00341
VPSSLDESPMAFYEP

GTF3C1

2071

Q12789
SEPDSYFSFEMPLTP

PSD3

466

Q9NYI0
PPRPSSSGYKMTTED

ZNF185

126

O15231
VYPEPSTSTTMDFPE

SON

316

P18583
CEHGYASSFPSMPSP

MXI1

26

P50539