Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionstructural constituent of cytoskeleton

POTEF SPTA1 PPL POTEE PLEC DMD POTEI

7.24e-061301097GO:0005200
GeneOntologyMolecularFunctionstructural constituent of postsynaptic actin cytoskeleton

POTEF POTEE POTEI

2.53e-05111093GO:0098973
GeneOntologyMolecularFunctionstructural constituent of muscle

ACTN2 ASPH PLEC DMD

8.80e-05431094GO:0008307
GeneOntologyMolecularFunctioncytoskeletal protein binding

FKBP15 SPTA1 TRPC5 APC ACTN2 ENKD1 NME8 SSH3 CEP135 RP1 PLEC DMD KIF13A AGBL1 UTRN NOS3

3.03e-04109910916GO:0008092
GeneOntologyMolecularFunction3'-5' exonuclease activity

NME8 RAD50 RAD1 CNOT1

3.45e-04611094GO:0008408
GeneOntologyMolecularFunctionstructural constituent of postsynapse

POTEF POTEE POTEI

6.99e-04321093GO:0099186
GeneOntologyBiologicalProcesspositive regulation of cilium assembly

ENTR1 ASAP1 CEP135 RP1

3.28e-05351084GO:0045724
GeneOntologyBiologicalProcessmicrotubule-based process

SEMG2 APC APOB SIK3 CNTROB ENKD1 NME8 DNAAF5 AKAP4 DNAH12 PKD1 CEP135 NINL RP1 KIF13A DNAH8 DEUP1

3.45e-05105810817GO:0007017
GeneOntologyBiologicalProcesscell cycle process

RBL1 ENTR1 APC NASP TEX15 STOX1 CNTROB ENKD1 RAD50 TAOK3 RAD1 PKD1 CEP135 SGO2 PLEC KIF13A STAG3 DEUP1 CDC23 KNL1

5.25e-05144110820GO:0022402
GeneOntologyBiologicalProcesscilium assembly

ENTR1 CNTROB ENKD1 NME8 ASAP1 DNAAF5 AKAP4 CEP135 RP1 DNAH8

1.14e-0444410810GO:0060271
GeneOntologyBiologicalProcesspositive regulation of organelle assembly

ENTR1 ASAP1 CEP135 RP1 CNOT1

1.58e-04971085GO:1902117
GeneOntologyBiologicalProcesspositive regulation of growth hormone receptor signaling pathway

ADRM1 JAK2

1.62e-0441082GO:0060399
GeneOntologyBiologicalProcesscilium organization

ENTR1 CNTROB ENKD1 NME8 ASAP1 DNAAF5 AKAP4 CEP135 RP1 DNAH8

2.01e-0447610810GO:0044782
GeneOntologyBiologicalProcessregulation of organelle organization

SPTA1 ENTR1 APC TSC1 ACTN2 STOX1 CNTROB ASAP1 RAD50 SSH3 RAD1 PKD1 CEP135 SGO2 RP1 CNOT1 CDC23 KNL1

2.01e-04134210818GO:0033043
GeneOntologyBiologicalProcessplasma membrane bounded cell projection assembly

ENTR1 APC ACTN2 CNTROB ENKD1 NME8 ASAP1 DNAAF5 AKAP4 CEP135 RP1 DNAH8

2.03e-0467010812GO:0120031
GeneOntologyBiologicalProcesspositive regulation of organelle organization

ENTR1 APC TSC1 ACTN2 ASAP1 RAD50 CEP135 SGO2 RP1 CNOT1 CDC23

2.12e-0457410811GO:0010638
GeneOntologyBiologicalProcessregulation of protein depolymerization

SPTA1 APC ACTN2 ASPH RP1

2.28e-041051085GO:1901879
GeneOntologyBiologicalProcesscell projection assembly

ENTR1 APC ACTN2 CNTROB ENKD1 NME8 ASAP1 DNAAF5 AKAP4 CEP135 RP1 DNAH8

2.48e-0468510812GO:0030031
GeneOntologyBiologicalProcesspositive regulation of cellular component organization

VLDLR LRRN1 ENTR1 TRPC5 APC TSC1 ACTN2 RUFY3 ASAP1 RAD50 SNAP91 CEP135 SGO2 RP1 DMD CNOT1 ADGRL3 CDC23

2.49e-04136610818GO:0051130
GeneOntologyBiologicalProcessregulation of cilium assembly

ENTR1 CNTROB ASAP1 CEP135 RP1

2.61e-041081085GO:1902017
GeneOntologyBiologicalProcesspositive regulation of cell projection organization

VLDLR ENTR1 TRPC5 APC RUFY3 ASAP1 SNAP91 CEP135 RP1 DMD

2.70e-0449410810GO:0031346
GeneOntologyCellularComponentaxon

FKBP15 POTEF SPTA1 TRPC5 APC TSC1 ADAM10 RUFY3 ATL1 POTEE SNAP91 SBF2 PLEC DMD POTEI ADGRL3

1.34e-0589110816GO:0030424
GeneOntologyCellularComponentsperm fibrous sheath

AKAP3 NME8 AKAP4

3.69e-05131083GO:0035686
GeneOntologyCellularComponentpolymeric cytoskeletal fiber

POTEF APC TSC1 ACTN2 ENKD1 PPL POTEE DNAH12 NINL RP1 PLEC DMD POTEI KIF13A DNAH8

5.92e-0589910815GO:0099513
GeneOntologyCellularComponentaxonemal dynein complex

NME8 DNAH12 DNAH8

2.84e-04251083GO:0005858
GeneOntologyCellularComponentsupramolecular fiber

POTEF APC TSC1 ACTN2 ENKD1 PPL POTEE AKAP4 DNAH12 NINL RP1 PLEC DMD POTEI KIF13A DNAH8

3.58e-04117910816GO:0099512
GeneOntologyCellularComponentsupramolecular polymer

POTEF APC TSC1 ACTN2 ENKD1 PPL POTEE AKAP4 DNAH12 NINL RP1 PLEC DMD POTEI KIF13A DNAH8

3.85e-04118710816GO:0099081
GeneOntologyCellularComponentGolgi apparatus subcompartment

COG3 ADAM10 ATL1 ASAP1 VPS52 RGS20 PIK3C2A KIF13A GOLGB1

4.88e-044431089GO:0098791
GeneOntologyCellularComponentNuA4 histone acetyltransferase complex

POTEF POTEE POTEI

5.96e-04321083GO:0035267
GeneOntologyCellularComponentH4/H2A histone acetyltransferase complex

POTEF POTEE POTEI

5.96e-04321083GO:0043189
GeneOntologyCellularComponentextrinsic component of plasma membrane

APC PPL JAK2 SNAP91 GNA15

7.30e-041371085GO:0019897
GeneOntologyCellularComponentactin filament

POTEF TSC1 ACTN2 POTEE POTEI

9.71e-041461085GO:0005884
GeneOntologyCellularComponenttrans-Golgi network

COG3 ADAM10 ASAP1 VPS52 RGS20 PIK3C2A KIF13A

1.06e-033061087GO:0005802
GeneOntologyCellularComponentextrinsic component of membrane

APC PPL JAK2 SNAP91 PIK3C2A GNA15

1.25e-032301086GO:0019898
GeneOntologyCellularComponentcohesin complex

SGO2 STAG3

1.41e-03111082GO:0008278
GeneOntologyCellularComponentmicrotubule associated complex

NME8 DNAH12 RP1 KIF13A DNAH8

1.50e-031611085GO:0005875
GeneOntologyCellularComponentsperm principal piece

AKAP3 NME8 AKAP4

1.52e-03441083GO:0097228
GeneOntologyCellularComponentH4 histone acetyltransferase complex

POTEF POTEE POTEI

1.63e-03451083GO:1902562
GeneOntologyCellularComponentouter dynein arm

NME8 DNAH8

1.69e-03121082GO:0036157
DomainSpectrin_repeat

SPTA1 ACTN2 PPL PLEC DMD UTRN

1.39e-08291086IPR002017
DomainSPEC

SPTA1 ACTN2 PPL PLEC DMD UTRN

2.61e-08321086SM00150
DomainSpectrin/alpha-actinin

SPTA1 ACTN2 PPL PLEC DMD UTRN

2.61e-08321086IPR018159
DomainSpectrin

SPTA1 ACTN2 DMD UTRN

8.60e-06231084PF00435
DomainACTININ_2

ACTN2 PLEC DMD UTRN

8.60e-06231084PS00020
DomainACTININ_1

ACTN2 PLEC DMD UTRN

8.60e-06231084PS00019
DomainActinin_actin-bd_CS

ACTN2 PLEC DMD UTRN

8.60e-06231084IPR001589
DomainAKAP_110

AKAP3 AKAP4

3.31e-0521082IPR020799
DomainDystrophin

DMD UTRN

3.31e-0521082IPR016344
DomainAKAP_110

AKAP3 AKAP4

3.31e-0521082SM00807
DomainI-BAR_dom

ARHGAP42 ARHGAP10 ASAP1

5.16e-05131083IPR013606
DomainAKAP_110_C

AKAP3 AKAP4

9.90e-0531082IPR018292
DomainActin_CS

POTEF POTEE POTEI

9.97e-05161083IPR004001
DomainACTINS_2

POTEF POTEE POTEI

1.21e-04171083PS00432
DomainActin/actin-like_CS

POTEF POTEE POTEI

1.44e-04181083IPR020902
DomainACTINS_ACT_LIKE

POTEF POTEE POTEI

1.70e-04191083PS01132
DomainSTAG

STAG3L4 STAG3

1.97e-0441082PF08514
DomainSPHK1-interactor_AKAP_110

AKAP3 AKAP4

1.97e-0441082IPR008382
DomainSTAG

STAG3L4 STAG3

1.97e-0441082IPR013721
DomainAKAP_110

AKAP3 AKAP4

1.97e-0441082PF05716
DomainAnk_2

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

2.53e-042151087PF12796
DomainRII_binding_1

AKAP3 AKAP4

3.28e-0451082PF10522
DomainRII_binding_1

AKAP3 AKAP4

3.28e-0451082IPR018459
DomainAnk

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

3.62e-042281087PF00023
DomainTRP_2

TRPC7 TRPC5

4.89e-0461082PF08344
DomainEFhand_Ca_insen

SPTA1 ACTN2

4.89e-0461082PF08726
DomainTRP_dom

TRPC7 TRPC5

4.89e-0461082IPR013555
DomainEF-hand_Ca_insen

SPTA1 ACTN2

4.89e-0461082IPR014837
DomainEF-hand_dom_typ1

DMD UTRN

4.89e-0461082IPR015153
DomainEF-hand_dom_typ2

DMD UTRN

4.89e-0461082IPR015154
DomainEF-hand_2

DMD UTRN

4.89e-0461082PF09068
DomainEF-hand_3

DMD UTRN

4.89e-0461082PF09069
DomainCH

ACTN2 PLEC DMD UTRN

5.46e-04651084SM00033
Domain-

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

5.97e-0424810871.25.40.20
DomainANK

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

6.41e-042511087SM00248
DomainANK_REPEAT

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

6.72e-042531087PS50088
DomainPlectin

PPL PLEC

6.83e-0471082PF00681
DomainTRPC_channel

TRPC7 TRPC5

6.83e-0471082IPR002153
DomainPlectin_repeat

PPL PLEC

6.83e-0471082IPR001101
DomainPLEC

PPL PLEC

6.83e-0471082SM00250
DomainAnkyrin_rpt-contain_dom

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

6.88e-042541087IPR020683
DomainANK_REP_REGION

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

6.88e-042541087PS50297
DomainCH

ACTN2 PLEC DMD UTRN

7.23e-04701084PF00307
DomainActin

POTEF POTEE POTEI

7.51e-04311083IPR004000
DomainActin

POTEF POTEE POTEI

7.51e-04311083PF00022
DomainACTIN

POTEF POTEE POTEI

7.51e-04311083SM00268
Domain-

ACTN2 PLEC DMD UTRN

7.63e-047110841.10.418.10
DomainAnkyrin_rpt

TRPC7 POTEF TRPC5 ACBD6 ASAP1 POTEE POTEI

8.25e-042621087IPR002110
DomainCH

ACTN2 PLEC DMD UTRN

8.47e-04731084PS50021
DomainCH-domain

ACTN2 PLEC DMD UTRN

9.37e-04751084IPR001715
DomainTRP_channel

TRPC7 TRPC5

1.76e-03111082IPR004729
DomainDynein_heavy_chain_D4_dom

DNAH12 DNAH8

2.88e-03141082IPR024317
DomainDynein_heavy_dom-2

DNAH12 DNAH8

2.88e-03141082IPR013602
DomainDHC_N2

DNAH12 DNAH8

2.88e-03141082PF08393
DomainATPase_dyneun-rel_AAA

DNAH12 DNAH8

2.88e-03141082IPR011704
DomainAAA_8

DNAH12 DNAH8

2.88e-03141082PF12780
DomainAAA_5

DNAH12 DNAH8

2.88e-03141082PF07728
DomainDHC_fam

DNAH12 DNAH8

3.31e-03151082IPR026983
DomainDynein_heavy

DNAH12 DNAH8

3.31e-03151082PF03028
DomainDynein_heavy_dom

DNAH12 DNAH8

3.31e-03151082IPR004273
DomainARM-type_fold

APC APOB RALGAPA2 DNAAF5 PIK3C2A AGBL1 STAG3

3.56e-033391087IPR016024
DomainZF_ZZ_2

DMD UTRN

4.77e-03181082PS50135
DomainZF_ZZ_1

DMD UTRN

4.77e-03181082PS01357
DomainZZ

DMD UTRN

4.77e-03181082PF00569
DomainBAR

ARHGAP42 ARHGAP10

5.31e-03191082PS51021
DomainZnf_ZZ

DMD UTRN

5.31e-03191082IPR000433
DomainZnF_ZZ

DMD UTRN

5.31e-03191082SM00291
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

FKBP15 ENTR1 APC AKAP3 TSC1 CHD1 NHLRC2 ATL1 VPS52 POLR3B CEP135 RPRD2 ZMYM1 KNL1

9.64e-087331111434672954
Pubmed

Plectin 1f scaffolding at the sarcolemma of dystrophic (mdx) muscle fibers through multiple interactions with beta-dystroglycan.

PLEC DMD UTRN

1.26e-074111317389230
Pubmed

Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.

FKBP15 ADRM1 RBL1 CHD1 SIK3 GLCCI1 RAD50 JAK2 PHKA2 TAOK3 DDX60L PLEC UTRN CDC23 KNL1

2.16e-079101111536736316
Pubmed

Transcriptome analysis of mouse stem cells and early embryos.

A2M ARHGAP10 ZGRF1 RALGAPA2 GLCCI1 ASAP1 SNAP91 SGO2 PLEC UTRN

2.75e-073631111014691545
Pubmed

Human spermatozoa contain multiple targets for protein S-nitrosylation: an alternative mechanism of the modulation of sperm function by nitric oxide?

SEMG2 AKAP3 AKAP4

3.15e-075111317683036
Pubmed

Functional proteomics mapping of a human signaling pathway.

THAP5 A2M PPL PHKA2 PKD1 CEP135 ZNF76 PLEC KIF13A UTRN GOLGB1 KNL1

4.44e-075911111215231748
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

A2M FKBP15 ADRM1 ARHGAP10 CHD1 NHLRC2 PPL RAD50 PWP1 DNAAF5 ASPH DMD PRORP UTRN DNAJC3

5.11e-079741111528675297
Pubmed

Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.

A2M ADRM1 ARHGAP10 CHD1 APOB PWP1 POTEE DNAH12 ASPH PLEC DEUP1

5.84e-074961111131343991
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

A2M ADRM1 RBL1 NASP NIF3L1 APOB CNTROB RAD50 COPS4 DMD KIF13A STAG3 GOLGB1

9.01e-077541111335906200
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

ZGRF1 TEX15 RAD50 PWP1 PLEC DMD KIF13A GOLGB1

9.07e-07234111836243803
Pubmed

Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.

ZGRF1 APC RAD50 ZNF462 PLEC UTRN CNOT1 GOLGB1 CDC23 KNL1

9.89e-074181111034709266
Pubmed

Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.

POTEF SPTA1 PKD1 NINL PLEC DMD DNAH8

2.46e-06187111726460568
Pubmed

Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.

ZGRF1 ENTR1 APC TSC1 RUFY3 RAD50 POTEE POTEI GOLGB1 CDC23 KNL1

3.03e-065881111138580884
Pubmed

Phosphoproteome analysis of the human mitotic spindle.

PPL PWP1 PHKA2 SGO2 PLEC CDC23 KNL1

5.29e-06210111716565220
Pubmed

Comparison of tear protein levels in breast cancer patients and healthy controls using a de novo proteomic approach.

POTEF RALGAPA2 POTEE POTEI CNOT1 STAG3

8.74e-06149111622664934
Pubmed

Decreased myocardial nNOS, increased iNOS and abnormal ECGs in mouse models of Duchenne muscular dystrophy.

DMD UTRN

1.01e-052111210525423
Pubmed

In Vivo Genome Editing Restores Dystrophin Expression and Cardiac Function in Dystrophic Mice.

DMD UTRN

1.01e-052111228790199
Pubmed

Metabolic dysfunction and altered mitochondrial dynamics in the utrophin-dystrophin deficient mouse model of duchenne muscular dystrophy.

DMD UTRN

1.01e-052111225859846
Pubmed

G-utrophin, the autosomal homologue of dystrophin Dp116, is expressed in sensory ganglia and brain.

DMD UTRN

1.01e-05211127731967
Pubmed

Role of dystrophin and utrophin for assembly and function of the dystrophin glycoprotein complex in non-muscle tissue.

DMD UTRN

1.01e-052111216710609
Pubmed

Nonclinical Exon Skipping Studies with 2'-O-Methyl Phosphorothioate Antisense Oligonucleotides in mdx and mdx-utrn-/- Mice Inspired by Clinical Trial Results.

DMD UTRN

1.01e-052111230672725
Pubmed

Talin, vinculin and DRP (utrophin) concentrations are increased at mdx myotendinous junctions following onset of necrosis.

DMD UTRN

1.01e-05211127962191
Pubmed

Does utrophin expression in muscles of mdx mice during postnatal development functionally compensate for dystrophin deficiency?

DMD UTRN

1.01e-05211128021701
Pubmed

Correlation of Utrophin Levels with the Dystrophin Protein Complex and Muscle Fibre Regeneration in Duchenne and Becker Muscular Dystrophy Muscle Biopsies.

DMD UTRN

1.01e-052111226974331
Pubmed

Androgen receptor agonists increase lean mass, improve cardiopulmonary functions and extend survival in preclinical models of Duchenne muscular dystrophy.

DMD UTRN

1.01e-052111228453658
Pubmed

A quantitative study of bioenergetics in skeletal muscle lacking utrophin and dystrophin.

DMD UTRN

1.01e-052111211801396
Pubmed

Apo-dystrophin-1 and apo-dystrophin-2, products of the Duchenne muscular dystrophy locus: expression during mouse embryogenesis and in cultured cell lines.

DMD UTRN

1.01e-05211127987307
Pubmed

Comparative analysis of the human dystrophin and utrophin gene structures.

DMD UTRN

1.01e-052111211861579
Pubmed

Distinct mechanical properties in homologous spectrin-like repeats of utrophin.

DMD UTRN

1.01e-052111230914715
Pubmed

Comparison of skeletal muscle pathology and motor function of dystrophin and utrophin deficient mouse strains.

DMD UTRN

1.01e-052111222284942
Pubmed

Haploinsufficiency of utrophin gene worsens skeletal muscle inflammation and fibrosis in mdx mice.

DMD UTRN

1.01e-052111217889902
Pubmed

Matricellular Protein CCN5 Gene Transfer Ameliorates Cardiac and Skeletal Dysfunction in mdx/utrn (±) Haploinsufficient Mice by Reducing Fibrosis and Upregulating Utrophin Expression.

DMD UTRN

1.01e-052111235557546
Pubmed

Characterization of the Ang/Tie2 Signaling Pathway in the Diaphragm Muscle of DMD Mice.

DMD UTRN

1.01e-052111237626761
Pubmed

A primate-specific POTE-actin fusion protein plays a role in apoptosis.

POTEF POTEE

1.01e-052111219669888
Pubmed

Molecular heterogeneity of the dystrophin-associated protein complex in the mouse kidney nephron: differential alterations in the absence of utrophin and dystrophin.

DMD UTRN

1.01e-052111215565469
Pubmed

The N- and C-Terminal Domains Differentially Contribute to the Structure and Function of Dystrophin and Utrophin Tandem Calponin-Homology Domains.

DMD UTRN

1.01e-052111226516677
Pubmed

Assessment of cardiac function in three mouse dystrophinopathies by magnetic resonance imaging.

DMD UTRN

1.01e-052111222209498
Pubmed

A Protocol for Simultaneous In Vivo Imaging of Cardiac and Neuroinflammation in Dystrophin-Deficient MDX Mice Using [18F]FEPPA PET.

DMD UTRN

1.01e-052111237108685
Pubmed

Prevention of the dystrophic phenotype in dystrophin/utrophin-deficient muscle following adenovirus-mediated transfer of a utrophin minigene.

DMD UTRN

1.01e-052111210694796
Pubmed

Enhanced currents through L-type calcium channels in cardiomyocytes disturb the electrophysiology of the dystrophic heart.

DMD UTRN

1.01e-052111224337461
Pubmed

Activation of calcineurin and stress activated protein kinase/p38-mitogen activated protein kinase in hearts of utrophin-dystrophin knockout mice.

DMD UTRN

1.01e-052111211297940
Pubmed

Rescue of severely affected dystrophin/utrophin-deficient mice through scAAV-U7snRNA-mediated exon skipping.

DMD UTRN

1.01e-052111222388933
Pubmed

Functional correction in mouse models of muscular dystrophy using exon-skipping tricyclo-DNA oligomers.

DMD UTRN

1.01e-052111225642938
Pubmed

Satellite cells and utrophin are not directly correlated with the degree of skeletal muscle damage in mdx mice.

DMD UTRN

1.01e-052111215703201
Pubmed

Utrophin suppresses low frequency oscillations and coupled gating of mechanosensitive ion channels in dystrophic skeletal muscle.

DMD UTRN

1.01e-052111225941878
Pubmed

Duchenne muscular dystrophy and the neuromuscular junction: the utrophin link.

DMD UTRN

1.01e-05211129297964
Pubmed

SERCA1 overexpression minimizes skeletal muscle damage in dystrophic mouse models.

DMD UTRN

1.01e-052111225652448
Pubmed

Utrophin Compensates dystrophin Loss during Mouse Spermatogenesis.

DMD UTRN

1.01e-052111228785010
Pubmed

Restoration of all dystrophin protein interactions by functional domains in trans does not rescue dystrophy.

DMD UTRN

1.01e-052111216307000
Pubmed

Expression of the dystrophin isoform Dp116 preserves functional muscle mass and extends lifespan without preventing dystrophy in severely dystrophic mice.

DMD UTRN

1.01e-052111221949353
Pubmed

Dystrophin and utrophin "double knockout" dystrophic mice exhibit a spectrum of degenerative musculoskeletal abnormalities.

DMD UTRN

1.01e-052111223097179
Pubmed

The role of utrophin and Dp71 for assembly of different dystrophin-associated protein complexes (DPCs) in the choroid plexus and microvasculature of the brain.

DMD UTRN

1.01e-052111215501597
Pubmed

Enhanced expression of the alpha 7 beta 1 integrin reduces muscular dystrophy and restores viability in dystrophic mice.

DMD UTRN

1.01e-052111211257121
Pubmed

Systemic human minidystrophin gene transfer improves functions and life span of dystrophin and dystrophin/utrophin-deficient mice.

DMD UTRN

1.01e-052111218973234
Pubmed

Renin-angiotensin-aldosterone system inhibitors improve membrane stability and change gene-expression profiles in dystrophic skeletal muscles.

DMD UTRN

1.01e-052111227881412
Pubmed

Dystrophins, utrophins, and associated scaffolding complexes: role in mammalian brain and implications for therapeutic strategies.

DMD UTRN

1.01e-052111220625423
Pubmed

Utrophin influences mitochondrial pathology and oxidative stress in dystrophic muscle.

DMD UTRN

1.01e-052111229065908
Pubmed

Stabilization of the cardiac sarcolemma by sarcospan rescues DMD-associated cardiomyopathy.

DMD UTRN

1.01e-052111231039133
Pubmed

Developmentally regulated expression and localization of dystrophin and utrophin in the human fetal brain.

DMD UTRN

1.01e-052111211796130
Pubmed

Dystrophin and dystrophin-related protein in the brains of normal and mdx mice.

DMD UTRN

1.01e-05211128159184
Pubmed

Dystrophin and utrophin: genetic analyses of their role in skeletal muscle.

DMD UTRN

1.01e-052111210679963
Pubmed

TAT-μUtrophin mitigates the pathophysiology of dystrophin and utrophin double-knockout mice.

DMD UTRN

1.01e-052111221565990
Pubmed

Generation and characterization of transgenic mice with the full-length human DMD gene.

DMD UTRN

1.01e-052111218083704
Pubmed

Dystrophin and dystrophin-related protein (utrophin) distribution in normal and dystrophin-deficient skeletal muscles.

DMD UTRN

1.01e-05211128186702
Pubmed

Contemporary cardiac issues in Duchenne muscular dystrophy. Working Group of the National Heart, Lung, and Blood Institute in collaboration with Parent Project Muscular Dystrophy.

DMD UTRN

1.01e-052111225940966
Pubmed

Cardiac dysfunction and pathology in the dystrophin and utrophin-deficient mouse during development of dilated cardiomyopathy.

DMD UTRN

1.01e-052111222266080
Pubmed

Postnatal overexpression of the CT GalNAc transferase inhibits muscular dystrophy in mdx mice without altering muscle growth or neuromuscular development: evidence for a utrophin-independent mechanism.

DMD UTRN

1.01e-052111217300937
Pubmed

Early treatment with lisinopril and spironolactone preserves cardiac and skeletal muscle in Duchenne muscular dystrophy mice.

DMD UTRN

1.01e-052111221768542
Pubmed

Social stress is lethal in the mdx model of Duchenne muscular dystrophy.

DMD UTRN

1.01e-052111232192914
Pubmed

Metabolic remodeling of dystrophic skeletal muscle reveals biological roles for dystrophin and utrophin in adaptation and plasticity.

DMD UTRN

1.01e-052111233359740
Pubmed

Utrophin regulates modal gating of mechanosensitive ion channels in dystrophic skeletal muscle.

DMD UTRN

1.01e-052111224879867
Pubmed

Increased vulnerability to kainate-induced seizures in utrophin-knockout mice.

DMD UTRN

1.01e-052111212028357
Pubmed

Excitation-contraction coupling alterations in mdx and utrophin/dystrophin double knockout mice: a comparative study.

DMD UTRN

1.01e-052111220130206
Pubmed

Analysis of gene expression differences between utrophin/dystrophin-deficient vs mdx skeletal muscles reveals a specific upregulation of slow muscle genes in limb muscles.

DMD UTRN

1.01e-052111216525850
Pubmed

Lack of AKAP3 disrupts integrity of the subcellular structure and proteome of mouse sperm and causes male sterility.

AKAP3 AKAP4

1.01e-052111231969357
Pubmed

Cytolinker cross-talk: periplakin N-terminus interacts with plectin to regulate keratin organisation and epithelial migration.

PPL PLEC

1.01e-052111217662978
Pubmed

Distribution of dystrophin- and utrophin-associated protein complexes during activation of human neutrophils.

DMD UTRN

1.01e-052111220434517
Pubmed

Plasma lipidomic analysis shows a disease progression signature in mdx mice.

DMD UTRN

1.01e-052111234155298
Pubmed

Dystrophic changes in extraocular muscles after gamma irradiation in mdx:utrophin(+/-) mice.

DMD UTRN

1.01e-052111224466085
Pubmed

The Angiotensin Converting Enzyme Inhibitor Lisinopril Improves Muscle Histopathology but not Contractile Function in a Mouse Model of Duchenne Muscular Dystrophy.

DMD UTRN

1.01e-052111227110493
Pubmed

Rapid depletion of muscle progenitor cells in dystrophic mdx/utrophin-/- mice.

DMD UTRN

1.01e-052111224781208
Pubmed

Isolation and characterization of a genomic clone from the murine utrophin locus.

DMD UTRN

1.01e-05211128268660
Pubmed

Supplementation with a selective amino acid formula ameliorates muscular dystrophy in mdx mice.

DMD NOS3

1.01e-052111230279586
Pubmed

Characterization of neuromuscular synapse function abnormalities in multiple Duchenne muscular dystrophy mouse models.

DMD UTRN

1.01e-052111227037492
Pubmed

Improvement in survival and muscle function in an mdx/utrn(-/-) double mutant mouse using a human retinal dystrophin transgene.

DMD UTRN

1.01e-052111216487708
Pubmed

Voltage-gated ion channel dysfunction precedes cardiomyopathy development in the dystrophic heart.

DMD UTRN

1.01e-052111221677768
Pubmed

Consequences of the combined deficiency in dystrophin and utrophin on the mechanical properties and myosin composition of some limb and respiratory muscles of the mouse.

DMD UTRN

1.01e-05211129713852
Pubmed

Skeletal muscle fibrosis in the mdx/utrn+/- mouse validates its suitability as a murine model of Duchenne muscular dystrophy.

DMD UTRN

1.01e-052111225607927
Pubmed

Developmental studies of dystrophin-positive fibers in mdx, and DRP localization.

DMD UTRN

1.01e-05211128433092
Pubmed

Second-generation compound for the modulation of utrophin in the therapy of DMD.

DMD UTRN

1.01e-052111225935002
Pubmed

Utrophin deficiency worsens cardiac contractile dysfunction present in dystrophin-deficient mdx mice.

DMD UTRN

1.01e-052111216024571
Pubmed

Utility of dystrophin and utrophin staining in childhood muscular dystrophy.

DMD UTRN

1.01e-052111216295426
Pubmed

Dystrophin is a microtubule-associated protein.

DMD UTRN

1.01e-052111219651889
Pubmed

Skeletal muscle-specific expression of a utrophin transgene rescues utrophin-dystrophin deficient mice.

DMD UTRN

1.01e-05211129590295
Pubmed

Utrophin haploinsufficiency does not worsen the functional performance, resistance to eccentric contractions and force production of dystrophic mice.

DMD UTRN

1.01e-052111229879154
Pubmed

Identification of Dp71 isoforms in the platelet membrane cytoskeleton. Potential role in thrombin-mediated platelet adhesion.

DMD UTRN

1.01e-052111212370193
Pubmed

Longitudinal metabolomic analysis of plasma enables modeling disease progression in Duchenne muscular dystrophy mouse models.

DMD UTRN

1.01e-052111232025735
Pubmed

Lifelong quercetin enrichment and cardioprotection in Mdx/Utrn+/- mice.

DMD UTRN

1.01e-052111227836895
Pubmed

BGP-15 Improves Aspects of the Dystrophic Pathology in mdx and dko Mice with Differing Efficacies in Heart and Skeletal Muscle.

DMD UTRN

1.01e-052111227750047
Pubmed

Prevention of dystrophin-deficient cardiomyopathy in twenty-one-month-old carrier mice by mosaic dystrophin expression or complementary dystrophin/utrophin expression.

DMD UTRN

1.01e-052111217967782
InteractionACTA1 interactions

POTEF SPTA1 TRIM31 TSC1 ACTN2 POTEE FTH1 PLEC DMD POTEI UTRN

5.94e-0637111011int:ACTA1
InteractionPXN interactions

ENTR1 APC ADAM10 CNTROB ASAP1 PIK3C2A PKD1 CNOT1 GOLGB1 CDC23

1.48e-0533411010int:PXN
Cytoband12q23.3

TTC41P PWP1 POLR3B

8.51e-0535111312q23.3
Cytoband9p24

VLDLR JAK2

1.61e-04811129p24
Cytoband2q21.1

POTEF POTEE POTEI

3.85e-045811132q21.1
GeneFamilyAnkyrin repeat domain containing|POTE ankyrin domain containing

POTEF POTEE POTEI

1.42e-0513683685
GeneFamilyEF-hand domain containing|Plakins

PPL PLEC

3.85e-048682939
GeneFamilyDyneins, axonemal

DNAH12 DNAH8

1.83e-0317682536
GeneFamilyZinc fingers ZZ-type|Lysine acetyltransferases

DMD UTRN

2.05e-031868291
GeneFamilyAnkyrin repeat domain containing

POTEF ACBD6 ASAP1 POTEE POTEI

2.16e-03242685403
GeneFamilyArmadillo repeat containing|Protein phosphatase 1 regulatory subunits

FKBP15 TRPC5 APC KNL1

4.81e-03181684694
GeneFamilyTransient receptor potential cation channels

TRPC7 TRPC5

4.95e-0328682249
GeneFamilyZinc fingers MYND-type|A-kinase anchoring proteins

AKAP3 AKAP4

5.30e-0329682396
CoexpressionMURARO_PANCREAS_BETA_CELL

THAP5 VLDLR APC GLCCI1 PPL RUFY3 ASAP1 RAD50 SNAP91 PIK3C2A FTH1 KIF13A UTRN DNAJC3 GOLGB1

1.10e-0594611115M39169
CoexpressionGSE16450_IMMATURE_VS_MATURE_NEURON_CELL_LINE_12H_IFNA_STIM_DN

TEX15 SIK3 PWP1 JAK2 RPRD2 NOS3 GOLGB1

2.36e-052001117M7418
CoexpressionMANNE_COVID19_NONICU_VS_HEALTHY_DONOR_PLATELETS_DN

A2M AFF2 HEMGN DNAH12 FCER1A DMD UTRN

2.94e-052071117M38977
CoexpressionGABRIELY_MIR21_TARGETS

APC GLCCI1 RUFY3 POLR3B PIK3C2A DMD UTRN KNL1

3.28e-052891118M2196
CoexpressionLAKE_ADULT_KIDNEY_C28_INTERSTITIUM

A2M ARHGAP10 PLXDC2 SBF2 UTRN

3.30e-05861115M39247
CoexpressionBASAKI_YBX1_TARGETS_DN

VLDLR STOX1 GLCCI1 RUFY3 DNAH12 SBF2 GLRX ASPH DNAJC3

5.07e-053981119M14877
CoexpressionLAKE_ADULT_KIDNEY_C27_VASCULAR_SMOOTH_MUSCLE_CELLS_AND_PERICYTES

A2M SIK3 DMD KIF13A UTRN ADGRL3

5.27e-051551116M39246
CoexpressionRODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_UP

FKBP15 ADRM1 APC ADAM10 ASAP1 RAD50 GLRX SGO2 ATP13A3 PLEC CNOT1 KNL1

5.62e-0572111112M10237
CoexpressionMANNO_MIDBRAIN_NEUROTYPES_HGABA

FKBP15 ARPP21 AFF2 APC SIK3 RUFY3 ATL1 ZNF462 TAOK3 SNAP91 PCDH19 SBF2 NINL KIF13A ADGRL3

6.67e-05110611115M39071
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_1000

ARHGAP42 VLDLR ENTR1 APC NASP CHD1 ASAP1 PIK3C2A ATP13A3 UTRN DNAJC3

4.87e-0637911111gudmap_developingKidney_e15.5_1000_k3
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_k-means-cluster#4_top-relative-expression-ranked_1000

ENTR1 APC NASP CHD1 ASAP1 PIK3C2A ATP13A3 KIF13A DNAJC3 ADGRL3 CDC23

5.65e-0638511111gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_k-means-cluster#3_top-relative-expression-ranked_500

ARHGAP42 VLDLR ENTR1 APC CHD1 ATP13A3 DNAJC3 CDC23

1.08e-052011118gudmap_developingKidney_e15.5_500_k3
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_top-relative-expression-ranked_1000

PUS3 LRRN1 RBL1 ZGRF1 APC NASP RUFY3 PLXDC2 SNAP91 PIK3C2A NINL RPRD2 ATP13A3 CDC23 KNL1

1.32e-0577911115gudmap_developingKidney_e15.5_Cap mesenchyme_1000
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_top-relative-expression-ranked_1000

LRRN1 SPTA1 MIER3 HEMGN SSMEM1 NASP TSC1 TEX15 RUFY3 RNF170 SNAP91 PLEC DNAH8 UTRN STAG3

1.67e-0579511115gudmap_developingGonad_e16.5_ovary_1000
CoexpressionAtlasDevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000

LRRN1 ENTR1 APC NASP CHD1 RUFY3 ASAP1 ZNF462 PIK3C2A ASPH ATP13A3 KIF13A DNAJC3 ADGRL3 CDC23

2.33e-0581811115gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_1000

VLDLR ENTR1 APC NASP CHD1 PIK3C2A ATP13A3 DNAJC3 CDC23

7.34e-053391119gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Ureteral Smooth Musc_emap-28812_k-means-cluster#5_top-relative-expression-ranked_1000

VLDLR APC CHD1 PIK3C2A ATP13A3 DNAJC3 KNL1

9.65e-052031117gudmap_developingKidney_e15.5_Ureteral Smooth Musc_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_Cap mesenchyme_emap-27738_k-means-cluster#5_top-relative-expression-ranked_1000

APC NASP PIK3C2A ATP13A3 CDC23 KNL1

1.19e-041461116gudmap_developingKidney_e15.5_Cap mesenchyme_1000_k5
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#4_top-relative-expression-ranked_200

VLDLR APC PIK3C2A ATP13A3

1.46e-04511114gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_200_k4
CoexpressionAtlasDevelopingKidney_e15.5_cortic collect duct_emap-28132_k-means-cluster#4_top-relative-expression-ranked_1000

ARHGAP42 VLDLR ENTR1 APC CHD1 PIK3C2A ATP13A3 DNAJC3 CDC23

1.57e-043751119gudmap_developingKidney_e15.5_cortic collect duct_1000_k4
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#5_top-relative-expression-ranked_500

VLDLR ENTR1 APC NASP PIK3C2A ATP13A3

1.71e-041561116gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_500_k5
CoexpressionAtlasDevelopingGonad_e14.5_ ovary_emap-6699_k-means-cluster#3_top-relative-expression-ranked_1000

PUS3 MIER3 HEMGN NASP TSC1 NHLRC2 UTRN

1.82e-042251117gudmap_developingGonad_e14.5_ ovary_1000_k3
CoexpressionAtlasDevelopingKidney_e15.5_ureter tip_flank cortic collct_emap-27752_k-means-cluster#3_top-relative-expression-ranked_100

VLDLR PIK3C2A ATP13A3

1.99e-04221113gudmap_developingKidney_e15.5_ureter tip_flank cortic collct_100_k3
CoexpressionAtlasDevelopingGonad_e16.5_ovary_emap-9563_k-means-cluster#2_top-relative-expression-ranked_1000

SPTA1 MIER3 NASP TSC1 RUFY3 PLEC UTRN

2.09e-042301117gudmap_developingGonad_e16.5_ovary_1000_k2
CoexpressionAtlasfacebase_RNAseq_e10.5_NeuroEpith_central_2500_K4

AFF2 LRRN1 APC NASP TSC1 CHD1 SIK3 RALGAPA2 RUFY3 RAD50 ZNF462 DNAAF5 SNAP91 CEP135 NINL DMD DEUP1 KNL1

2.58e-04137011118facebase_RNAseq_e10.5_NeuroEpith_central_2500_K4
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_1000

ARHGAP42 VLDLR ENTR1 APC NASP CHD1 ASAP1 PIK3C2A ATP13A3 UTRN DNAJC3 DEUP1 CDC23

2.63e-0479511113gudmap_developingKidney_e15.5_anlage of loop of Henle_1000
CoexpressionAtlasDevelopingKidney_e15.5_anlage of loop of Henle_emap-31283_top-relative-expression-ranked_500

ARHGAP42 VLDLR ENTR1 APC CHD1 ASAP1 ATP13A3 DNAJC3 CDC23

2.64e-044021119gudmap_developingKidney_e15.5_anlage of loop of Henle_500
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

TTC41P LRRN1 RBL1 APC NASP CHD1 RUFY3 RAD50 ZNF462 CEP135 SGO2 ZMYM1 DMD DEUP1 KNL1

4.10e-04106011115facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
CoexpressionAtlasDevelopingKidney_e15.5_Medullary collecting duct_emap-28063_k-means-cluster#4_top-relative-expression-ranked_1000

ENTR1 APC PIK3C2A ATP13A3 UTRN DNAJC3 CDC23

4.48e-042611117gudmap_developingKidney_e15.5_Medullary collecting duct_1000_k4
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)|Adult / Lineage, Cell type, age group and donor

FKBP15 TFEC ARHGAP10 ASAP1 PLXDC2 SBF2 FTH1 DDX60L

3.25e-08195111855e25f702af19146a161861cfd15f40bbda1dc35
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Enterocyte|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM31 APOB SLC13A2 ASAP1 GLRX FTH1 PLEC

2.78e-0717411172fbdb62e269acf4447b171700a615e878dde7f9f
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRIM31 APOB SLC13A2 ASAP1 GLRX FTH1 PLEC

2.78e-0717411177c52b5d8f1e65e5208c952be341fa155ed0e6e76
ToppCellCF-Myeloid|CF / Disease state, Lineage and Cell class

RALGAPA2 ASAP1 PLXDC2 SBF2 FTH1 ATP13A3 DDX60L

5.99e-071951117ecf604de496f389a49429d0bb211e1db6019cc8b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 ASAP1 DMD ADGRL3

5.48e-061771116a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 ASAP1 DMD ADGRL3

5.48e-0617711163645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCelldroplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP42 PPL PCDH19 DMD NOS3 DEUP1

6.63e-061831116351d575339038bd4a66f408da518c567444208e8
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell__prolif|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

A2M NASP RFX8 ASAP1 UTRN NOS3

6.84e-061841116688428103e8b19f45f2f65d70a0f30c904c8411c
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M ARHGAP10 ASAP1 DMD ADGRL3

7.05e-0618511167092436b4db90289516ed130ade596e3021cffaf
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M ARHGAP10 DMD UTRN ADGRL3

7.05e-06185111651dfe6ac7df8b330343b37e3bee71e5c65267189
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M ARHGAP10 ASAP1 DMD ADGRL3

7.05e-061851116a8ca7819066d5297ef6966e7f3e2c9f8a7673fdc
ToppCellLA-07._Pericyte|LA / Chamber and Cluster_Paper

ARHGAP42 A2M ARHGAP10 ASAP1 UTRN ADGRL3

7.05e-061851116ba5baa4d7f097108622674de5b7f4fd279843d24
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 A2M ARHGAP10 DMD UTRN ADGRL3

7.05e-061851116a8c02cec3c414f3a0da9f2d6d28ce563b0030705
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ARHGAP42 A2M AFF2 ARHGAP10 DMD UTRN

7.27e-061861116888e85a025bd982d36c910db0f5a3385b1ca3b28
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ADAM10 GLCCI1 PPL ZNF462 UTRN ADGRL3

7.73e-06188111663a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell(04)_Pre-ciliated|World / shred by cell type and Timepoint

STOX1 CNTROB ENKD1 CEP135 DNAH8 DEUP1

8.46e-06191111637cf121e6e80760c8519075b7845b9029958a988
ToppCellCOVID-19-kidney-Proliferating_T_cell|COVID-19 / Disease (COVID-19 only), tissue and cell type

RBL1 ZGRF1 SPTA1 HEMGN SGO2 KNL1

8.46e-061911116bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 ARHGAP10 ASAP1 DMD UTRN ADGRL3

8.46e-0619111167b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellRA-09._Endothelium_I|World / Chamber and Cluster_Paper

A2M RALGAPA2 ASAP1 PLXDC2 PIK3C2A NOS3

8.46e-061911116c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 ARHGAP10 ASAP1 DMD UTRN ADGRL3

8.46e-061911116cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellRA-09._Endothelium_I|RA / Chamber and Cluster_Paper

A2M RALGAPA2 PLXDC2 PIK3C2A UTRN NOS3

8.72e-0619211168a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D175|Adult / Lineage, Cell type, age group and donor

FKBP15 TFEC ARHGAP10 ASAP1 PLXDC2 DDX60L

8.72e-061921116733491e932350e3c216a626cc49c3cd3fe970a82
ToppCellfacs-Brain_Non-Myeloid-Striatum|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR ARPP21 ACTN2 STK32C SIK3 RUFY3

8.98e-061931116d8ccfb780a75bdf9141f41fb29a076958601ebb4
ToppCellnucseq|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

SIK3 ASAP1 PLXDC2 SBF2 ATP13A3 UTRN

8.98e-061931116779276e775cb2492e8dd36436295a536084a6415
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)|Children_(3_yrs) / Lineage, Cell type, age group and donor

FKBP15 TFEC ARHGAP10 PLXDC2 FTH1 DDX60L

9.25e-06194111669cf7c989ac355c459db13f9d4267b55adc3c174
ToppCellLA-09._Endothelium_I|World / Chamber and Cluster_Paper

A2M RALGAPA2 ASAP1 PLXDC2 PIK3C2A NOS3

9.52e-061951116fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCellImmune-alveolar_macrophage_(MARCO_positive)|World / Lineage, Cell type, age group and donor

FKBP15 TFEC ARHGAP10 PLXDC2 FTH1 DDX60L

9.52e-061951116f92114ef995e690a3bedc62c89c5fd6773d0d9f7
ToppCellCOVID-19-T_cells-Cycling_NK/T_cells|COVID-19 / group, cell type (main and fine annotations)

RBL1 ZGRF1 SPTA1 HEMGN SGO2 KNL1

9.52e-061951116764ed100c28d9bc93ee5ecabc5291c8f184d78da
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|COVID-19 / Disease (COVID-19 only), tissue and cell type

ARHGAP42 A2M AFF2 ARHGAP10 DMD ADGRL3

9.80e-061961116754a3613340932563cd8424d775e18b93c3a1aaa
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TFEC RUFY3 JAK2 FCER1A PLXDC2 GNA15

1.04e-051981116c1fe38594bd6292fcc60bdbb563376b454731d00
ToppCellAdult-Immune|Adult / Lineage, Cell type, age group and donor

TFEC ASAP1 PLXDC2 SBF2 FTH1 DDX60L

1.04e-0519811169bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCellPBMC-Control-Myeloid-cDC-cDC-cDC_0|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TFEC RUFY3 JAK2 FCER1A PLXDC2 GNA15

1.04e-051981116bfc15de70a7577a2860b53e1e6826a7b5ad23040
ToppCelldistal-Hematologic-Interstitial_Macrophage-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TFEC PLXDC2 FTH1 GNA15 ATP13A3 PLEC

1.07e-051991116e25a67a196f226b60b4aa0ff0cf4471d66333445
ToppCellLV-03._Atrial_Cardiomyocyte|LV / Chamber and Cluster_Paper

HEMGN APOB ACTN2 DMD POTEI

1.27e-0512011153b77bd0e3630cdd45001cecf5e47660a90ebc92e
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

CMKLR2 TRIM31 DMD AGBL1 ADGRL3

1.80e-05129111557b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellfacs-Aorta-Heart-3m-Myeloid-nan|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPC7 SPTA1 NME8 GNA15 AGBL1

2.58e-05139111522a769d5195ed761ef333ef542746e1ba617a698
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell-DC_c4-LILRA4|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NME8 PPL ZNF462 FCER1A BAHCC1

2.96e-051431115d0ed8c25da1327085e042c2e03cb7503e2c52ce0
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Myeloid-Dendritic-plasmacytoid_dendritic_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NME8 PPL ZNF462 FCER1A BAHCC1

2.96e-0514311158900b92a24289204b9ec7baccc11594fec7694f1
ToppCellfacs-Thymus-Flowthrough-24m-Lymphocytic-DN_to_DP_transition_(most_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ARPP21 LRRN1 MIOX SLC13A2 GLCCI1

4.76e-051581115c870fd17213129943562487338e2669e2930d719
ToppCellPND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-Treg|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

HEMGN GLRX SGO2 GNA15 KNL1

5.68e-051641115e5258efd6765acfc394708f697ec76acaef09079
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TFEC ARPP21 NASP SLC13A2 ATP13A3

6.37e-051681115a1755afa2cc50960ba60e07d84d61be429cdea72
ToppCellfacs-Large_Intestine-Proximal-3m-Epithelial-Enterocyte_(Proximal)|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MIER3 TRIM31 APOB SLC13A2 ASAP1

6.92e-0517111155d0d6c1ff610a703ae0b834a12823c5ff9012932
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RBL1 NASP CEP135 SGO2 ZNF76

7.12e-0517211152b6cd84c946b1e800caba452ae70145ea285fec1
ToppCelldroplet-Lung-nan-21m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR82 COG3 JAK2 GNA15 KNL1

7.31e-0517311152eb6e9fc3a3654f6f86fbd112e80a18814afd103
ToppCellfacs-Brain_Myeloid-Cerebellum-24m-Myeloid-microglial_cell|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

VLDLR HEMGN FCER1A FTH1 AGBL1

7.31e-051731115ef862e1d626bbc33191b433f483addff7f75ba16
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DMD DNAH8 UTRN ADGRL3

7.72e-051751115316f2ea930437bf1243b1c0f45e6bd864112c6f2
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

A2M DMD DNAH8 UTRN ADGRL3

7.72e-051751115a9f08e1e4c2997dcdd3e5d92daac480da19100b8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 UTRN ADGRL3

8.15e-0517711154943d040eee0f9dceaddc7498171281d170e271f
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-Pericyte-Pericyte_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

AFF2 CNTROB SGO2 STAG3 KNL1

8.15e-0517711152b63f0529ef73e0eede9b7ef1f08b0a0426a9c82
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 UTRN ADGRL3

8.15e-0517711153f2272b577c862dba8ccfb41184054bbd0ace6f5
ToppCell10x5'v1-week_14-16-Myeloid_macrophage-stroma-osteoclast|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

ARHGAP10 ACTN2 RFX8 PPL ZNF462

8.37e-051781115a28683690ab8a60eb18f3ef87ea85da4e95b22df
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ARHGAP42 TRIM31 ATP13A3 UTRN NOS3

8.82e-05180111567c5068b660cd5e727a665cefe3bd5f8ae887221
ToppCellRA-07._Pericyte|RA / Chamber and Cluster_Paper

ARHGAP42 ARHGAP10 ASAP1 UTRN ADGRL3

9.05e-0518111158dfb42d096db6c2df9b41303a7199d134d4bff07
ToppCellControl-Myeloid-Alveolar_macrophages|Control / group, cell type (main and fine annotations)

TFEC ARHGAP10 PLXDC2 FTH1 DDX60L

9.05e-0518111158d2102c8c86c59a82610f26f90946b290552e666
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP10 ADAM10 GLCCI1 UTRN ADGRL3

9.05e-051811115071f9bb5d39070cdc473d9b0e094d196bc702b56
ToppCellfacs-Skin-Skin_Anagen-18m-Epithelial-actively_dividing_stem_cell|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBL1 CNTROB SGO2 DNAH8 KNL1

9.29e-051821115bc6a120dedc813c58baac1428c39851a07b71ba7
ToppCell3'-Adult-LargeIntestine-Epithelial-Tuft-related-Microfold_cell|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TRIM31 SNAP91 GLRX DDX60L PLEC

9.29e-051821115b4f347fb684f6840c166d7473f3f56389f69c14b
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

A2M ARHGAP10 DMD KIF13A ADGRL3

9.53e-051831115818fd886e0188091310825f9145fa53328f2c979
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Mesenchymal-Myocytic_interstitial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 ARHGAP10 ASAP1 DMD ADGRL3

9.53e-051831115667717366cb181b8a04a347e64f0f5a4dfc6ee7f
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M SPTA1 APOB DMD ADGRL3

9.78e-0518411152cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M SPTA1 APOB DMD ADGRL3

9.78e-051841115ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

RAD50 PIK3C2A SGO2 UTRN KNL1

9.78e-051841115ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

A2M SPTA1 APOB DMD ADGRL3

9.78e-0518411152b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellLPS-antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ARHGAP42 LRRN1 STOX1 ATL1 DMD

1.00e-0418511156712512100ccef456d2e2bd201d0987986c92ac9
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP10 RUFY3 ASAP1 FCER1A GNA15

1.00e-041851115405bd4ba7ca7f7b625c49f1313ff946509e17c13
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Myeloid-Dendritic-conventional_dendritic_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

ARHGAP10 RUFY3 ASAP1 FCER1A GNA15

1.00e-0418511152aa5e9f6f167d27317a01d22392b59512333fa64
ToppCell3'_v3-blood-Myeloid_Dendritic-DC2|blood / Manually curated celltypes from each tissue

RUFY3 FCER1A FTH1 GNA15 DMD

1.05e-0418711159f3db9f0e5de34aeabfe5984f675bc7a65435df7
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.05e-041871115ec4b694487cc446999c7b27b119950a4f252c4b3
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.05e-04187111548bfdb3504c3fefe5db3abac4b790c369680ab4e
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.05e-041871115530e4e6d91b5c0d9aa4543caa2b734a1674c5788
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.05e-041871115958402fcc78f4c7a7d13d659d776f3817137975f
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

CHD1 SIK3 ATP13A3 UTRN GOLGB1

1.08e-041881115ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.08e-041881115b2d68a32314e9b099ed74d974079ad96359d1ae3
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

A2M ARHGAP10 DMD KIF13A ADGRL3

1.08e-04188111534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell10x5'v1-week_17-19-Myeloid_macrophage-stroma-osteoclast|week_17-19 / cell types per 3 fetal stages;per 3',per 5'

ARHGAP10 ACTN2 RFX8 PPL ZNF462

1.08e-041881115762b52f21d2bc5409f86746a904c4358490be9c0
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

A2M ARHGAP10 DMD KIF13A ADGRL3

1.11e-0418911156b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.11e-041891115fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCellRA-10._Endothelium_II|World / Chamber and Cluster_Paper

RALGAPA2 ASAP1 PIK3C2A ATP13A3 NOS3

1.11e-04189111575c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCellRV-15._Ventricular_Cardiomyocyte_III|RV / Chamber and Cluster_Paper

ACTN2 SIK3 JAK2 DDX60L DMD

1.14e-04190111593c3188dfeb0b2f9889f8ae9b9c1f2f34129c99b
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.14e-0419011155681c211baeed4af82a2bbc13420f6a7b487581c
ToppCellPCW_13-14-Hematologic_ErythroMegGranulo-Hem_Granulocytic-im_mast/basophil_(18)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

TFEC ARPP21 NME8 FCER1A GNA15

1.16e-04191111514b11244c330cc4fe897253aaaf0df80caa01a55
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.19e-04192111524e2f15f5767a97eb3b389922bcfd7b13805e1ce
ToppCellAdult-Immune-alveolar_macrophage_(MARCO_positive)-D122|Adult / Lineage, Cell type, age group and donor

FKBP15 TFEC ARHGAP10 PLXDC2 FTH1

1.22e-041931115cc1b6d3bf56e4a88f6fe23dd036a83cf5538c958
ToppCellLV-10._Endothelium_II|LV / Chamber and Cluster_Paper

RALGAPA2 ASAP1 PLXDC2 PIK3C2A NOS3

1.25e-041941115b6cc849fa08599bff9839ef382d190cc964e273e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M JAK2 DMD UTRN ADGRL3

1.25e-0419411155c3b2b05d1e4f146551fe4c920263d8e6ca34de3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M JAK2 DMD UTRN ADGRL3

1.25e-041941115ab9cad697f9209d2889bc02b43b502dfeb2ebfef
ToppCellmoderate-Epithelial-FOXN4+|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CEP135 SGO2 UTRN DEUP1 KNL1

1.25e-041941115dff3fb10372053951d41e0ccd41aac3ece6009bd
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP10 DMD UTRN ADGRL3

1.25e-041941115ebb038f94f49f5c655578d1b018676e10c6b7e3c
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

ARHGAP42 AFF2 ARHGAP10 DMD ADGRL3

1.25e-0419411155e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellChildren_(3_yrs)-Immune-alveolar_macrophage_(MARCO_positive)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

FKBP15 TFEC ARHGAP10 PLXDC2 ATP13A3

1.28e-0419511159d649ac7d2af313481069c95349efc0c68449e2b
ToppCellCOVID-19-kidney-Proliferating_T_cell|kidney / Disease (COVID-19 only), tissue and cell type

ZGRF1 SPTA1 HEMGN SGO2 KNL1

1.28e-0419511157e05e56f8d0a7a052830c7db12b10dace7d10760
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M ARHGAP10 DMD UTRN ADGRL3

1.31e-041961115b8759e6231e0254797d6c30930407b79440c57bb
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RALGAPA2 ASAP1 PIK3C2A NOS3

1.31e-0419611158f2031b1a9232c389517fbf3c29f47f9468b0077
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-G|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

LRRN1 NASP GLCCI1 ZNF462 KNL1

1.31e-0419611158faac7fbdee3a9297023c3151ef1751605413e44
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RALGAPA2 ASAP1 PIK3C2A NOS3

1.31e-04196111548b4a9cea97a55190217deaf51bf867608c5a9a7
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

A2M RALGAPA2 ASAP1 PIK3C2A NOS3

1.31e-041961115473980c827443464d08a0be28c53e3536369b12a
ToppCellParenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_CCL|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TFEC NME8 FCER1A PLXDC2 GNA15

1.35e-04197111561bda9b5102fdbce902bb976d1aa62f2c799d2fb
ToppCellmedial-Hematologic-Interstitial_Macrophage-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

TFEC PLXDC2 FTH1 GNA15 PLEC

1.35e-041971115b90c8a41e99c87b46be699d03cd49c97a2ad51af
ToppCell3'-Adult-SmallIntestine|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

A2M TFEC AFF2 APOB SLC13A2

1.35e-0419711151614bc5f41fd2c8385e58ed6b87ef1536421f29a
ToppCellLA-09._Endothelium_I|LA / Chamber and Cluster_Paper

A2M RALGAPA2 ASAP1 PIK3C2A NOS3

1.35e-041971115ab6d1ab586a188597a39854ef980b8955ebcc645
Drugtungstopterin

A2M APC TSC1 APOB PKD1 PLEC DMD GOLGB1

2.60e-071311118CID005460240
DrugNifuroxazide [965-52-6]; Down 200; 14.6uM; PC3; HT_HG-U133A

FKBP15 AFF2 APC TEX15 SSH3 KIF13A UTRN STAG3

4.83e-0619311184253_DN
DiseaseLipidemias

APC APOB NOS3

2.87e-05171053C1706412
DiseaseHyperlipidemia

APC APOB NOS3

2.87e-05171053C0020473
DiseaseX-linked mental retardation with cerebellar hypoplasia and distinctive facial appearance (implicated_via_orthology)

ARHGAP42 ARHGAP10

7.49e-0541052DOID:0080311 (implicated_via_orthology)
Diseaselevel of Phosphatidylethanolamine (16:0_18:2) in blood serum

SIK3 ADAM10 FTH1

8.39e-05241053OBA_2045136
Diseasenephrotic syndrome (biomarker_via_orthology)

A2M VLDLR APOB

8.39e-05241053DOID:1184 (biomarker_via_orthology)
Diseaselipid measurement, high density lipoprotein cholesterol measurement

TRIM31 APOB NHLRC2 SIK3 ADAM10 SBF2 KNL1

1.83e-043301057EFO_0004529, EFO_0004612
Diseasetriacylglycerol 52:4 measurement

APOB SIK3 CNOT1

2.87e-04361053EFO_0010416
Diseasehereditary spastic paraplegia (implicated_via_orthology)

ATL1 RNF170 ATP13A3

4.87e-04431053DOID:2476 (implicated_via_orthology)
Diseasecholesteryl esters to total lipids in small HDL percentage

APOB SIK3 ADAM10

4.87e-04431053EFO_0022254
Diseaselevel of Triacylglycerol (51:3) in blood serum

APOB SIK3

5.54e-04101052OBA_2045163
Diseasetemporomandibular joint disorder

DMD BAHCC1

5.54e-04101052EFO_0005279
Diseaselevel of Diacylglycerol (18:1_18:1) in blood serum

APOB SIK3

6.76e-04111052OBA_2045170
Diseasefree cholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

TRIM31 APOB NHLRC2 SIK3 ADAM10 SBF2

7.67e-043031056EFO_0004612, EFO_0020945
Diseasenicotine dependence (implicated_via_orthology)

TRPC7 TRPC5

8.09e-04121052DOID:0050742 (implicated_via_orthology)
Diseasefree cholesterol measurement, high density lipoprotein cholesterol measurement

APOB NHLRC2 SIK3 ADAM10 SBF2 KNL1

9.37e-043151056EFO_0004612, EFO_0008591
Diseasecardiomyopathy (biomarker_via_orthology)

ADAM10 NOS3

9.54e-04131052DOID:0050700 (biomarker_via_orthology)
Diseaseliver cirrhosis (implicated_via_orthology)

RAD50 NOS3

9.54e-04131052DOID:5082 (implicated_via_orthology)
Diseasegallbladder cancer (is_implicated_in)

APC APOB

9.54e-04131052DOID:3121 (is_implicated_in)
Diseasetriglycerides in very large HDL measurement

APOB SIK3 ADAM10

1.00e-03551053EFO_0022324
Diseasephospholipid measurement, high density lipoprotein cholesterol measurement

APOB NHLRC2 SIK3 ADAM10 SBF2 KNL1

1.03e-033211056EFO_0004612, EFO_0004639
Diseasevascular endothelial growth factor measurement

VLDLR ZNF462 STAG3L4

1.06e-03561053EFO_0004762
Diseaselevel of Phosphatidylethanolamine (18:1_18:1) in blood serum

SIK3 ADAM10

1.11e-03141052OBA_2045142
Diseaserostral middle frontal gyrus volume measurement

AGBL1 DEUP1

1.11e-03141052EFO_0010328
Diseasesystolic blood pressure, alcohol drinking

ARHGAP42 NHLRC2 PIK3C2A NOS3

1.15e-031281054EFO_0004329, EFO_0006335
Diseasetriglycerides in IDL measurement

APOB SIK3 ADAM10

1.17e-03581053EFO_0022149
Diseasetriacylglycerol 52:3 measurement

APOB SIK3

1.28e-03151052EFO_0010415
DiseaseAutosomal recessive primary microcephaly

CEP135 KNL1

1.28e-03151052cv:C3711387
DiseasePre-Eclampsia

STOX1 NOS3

1.46e-03161052C0032914
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

TSC1 PKD1

1.46e-03161052DOID:0110861 (implicated_via_orthology)
Diseasesickle cell anemia (is_implicated_in)

APOB NOS3

1.46e-03161052DOID:10923 (is_implicated_in)
Diseaseneuroimaging measurement

APC GLCCI1 ZNF462 SNAP91 PKD1 FTH1 COPS4 NINL PLEC AGBL1 BAHCC1

1.50e-03106910511EFO_0004346
DiseaseProstatic Neoplasms

APC CHD1 PPL JAK2 VPS52 RPRD2 DNAJC3 NOS3

1.63e-036161058C0033578
DiseaseMalignant neoplasm of prostate

APC CHD1 PPL JAK2 VPS52 RPRD2 DNAJC3 NOS3

1.63e-036161058C0376358
Diseasemyocardial infarction (implicated_via_orthology)

RAD50 JAK2 NOS3

1.70e-03661053DOID:5844 (implicated_via_orthology)
Diseaseresting heart rate

ARHGAP10 ASPH PLEC CDC23

2.01e-031491054EFO_0004351
Diseaseportal hypertension (implicated_via_orthology)

JAK2 NOS3

2.06e-03191052DOID:10762 (implicated_via_orthology)
Diseasecerebral infarction (is_marker_for)

A2M APOB

2.06e-03191052DOID:3526 (is_marker_for)
Diseaseplatelet crit

VLDLR TFEC HEMGN APOB NHLRC2 JAK2 ZNF76 RPRD2 RP1 PLEC

2.12e-0395210510EFO_0007985
Diseaseautism spectrum disorder (implicated_via_orthology)

TRPC5 TSC1 CHD1 TAOK3

2.16e-031521054DOID:0060041 (implicated_via_orthology)
Diseasemuscular dystrophy (implicated_via_orthology)

DMD UTRN

2.52e-03211052DOID:9884 (implicated_via_orthology)
Diseasedocosahexaenoic acid to total fatty acids percentage

APOB FTH1

2.52e-03211052EFO_0022262
Diseasecholangiocarcinoma (is_implicated_in)

APC ASPH

2.77e-03221052DOID:4947 (is_implicated_in)
DiseaseAutosomal Recessive Primary Microcephaly

CEP135 KNL1

2.77e-03221052C3711387
DiseasePrimary microcephaly

CEP135 KNL1

2.77e-03221052C0431350
Diseasetransitional cell carcinoma (is_implicated_in)

APC RAD50

2.77e-03221052DOID:2671 (is_implicated_in)
Diseaseobsolete_red blood cell distribution width

ARHGAP42 RBL1 SPTA1 ENTR1 HEMGN APOB SIK3 TAOK3 FTH1 COPS4 RP1 KNL1

3.04e-03134710512EFO_0005192
Diseasecholesterol:total lipids ratio, high density lipoprotein cholesterol measurement

APOB NHLRC2 SIK3 ADAM10 SBF2

3.12e-032761055EFO_0004612, EFO_0020943
Diseasehigh density lipoprotein particle size measurement

APOB NHLRC2 ADAM10 KNL1

3.24e-031701054EFO_0008592
Diseasepartial thromboplastin time

PLXDC2 AGBL1

3.29e-03241052EFO_0004310

Protein segments in the cluster

PeptideGeneStartEntry
EDSGEYKCQHQQVNE

FCER1A

86

P12319
KNALYQSCHEDENDV

BAHCC1

2571

Q9P281
LHEQLTESEQAAQCY

CDC23

476

Q9UJX2
VLEQQRQAQEHYNAT

ENKD1

226

Q9H0I2
QELNELDYHDAVNVN

ACTN2

466

P35609
YQDSLGHEVIVNNQC

AKAP4

751

Q5JQC9
LELNSEQNHDDYCLA

ADAM10

301

O14672
TELDEHNIQNYENTT

ATP13A3

1061

Q9H7F0
DLEQQCHYEQDRSAL

AFF2

11

P51816
SNCVQIIDRGYNHNE

ADGRL3

1216

Q9HAR2
QELQGEDHISAQNYV

GLCCI1

531

Q86VQ1
HLDYLIQATNETNVN

SNAP91

41

O60641
SYHVEETVSQDCNQD

ASPH

211

Q12797
TIYDRLEQEHNNLVN

DMD

3156

P11532
NIFDYCRENNIDHIT

ACBD6

161

Q9BR61
QLQQVEEYHNSEQER

DEUP1

351

Q05D60
CQQELTDDLHKQYQI

CHD1

376

O14646
QDYETAQEHNENDQQ

DNAJC3

361

Q13217
EQEIIDFIADNNNHY

ARPP21

171

Q9UBL0
DQDNEDCINRHNVYI

A2M

636

P01023
YDLLVNADVNSTQHQ

AGBL1

616

Q96MI9
QQIQDEDDQYSLVAS

RAD1

6

O60671
VFQGTDEQLNDLYHN

RAD50

296

Q92878
HCLITKNENEEYNLS

JAK2

451

O60674
LDREQHDQYNLTIQA

PCDH19

411

Q8TAB3
QEADIQVEQNRQHFY

ARHGAP10

161

A1A4S6
YHSDEQNDTQKQFCE

POTEF

591

A5A3E0
HQRDNCQQLNYLIET

GPR82

276

Q96P67
VQQNRAILDHQQFDY

SBF2

596

Q86WG5
NLNLNHVSDLYDEQL

DDX60L

351

Q5H9U9
SYHNQVELALQIENQ

PIK3C2A

556

O00443
LEAEYQQLQEDHQRQ

PPL

1066

O60437
NESTNEQLQIHYKVC

COPS4

176

Q9BT78
NNDYEANIVNEFDTH

DNAH8

811

Q96JB1
DSNTYAELQNAVAHQ

DNAH8

2081

Q96JB1
AKDEHLQQYQEVCAQ

FKBP15

816

Q5T1M5
VVDQCLDEYNQTHKT

DNAH12

2211

Q6ZR08
ADCNQEIATSHNIVY

KNL1

686

Q8NG31
SEYDQCLEENNQENR

GNA15

236

P30679
DNEQALYELLKCNHN

MIER3

246

Q7Z3K6
RQNAQEDEYIQSHNF

RALGAPA2

1566

Q2PPJ7
QSCLNLQEQYLEAHD

NASP

566

P49321
ENGELLYVADTNNHQ

NHLRC2

541

Q8NBF2
EHFSEICQESNIYQE

HEMGN

131

Q9BXL5
SQLDHLYRDEVQNAQ

NOS3

1051

P29474
YHSDEQNDTQKQFCE

POTEE

591

Q6S8J3
IVNEQLQRSVDDYQH

CEP135

671

Q66GS9
QNYHQDSEAAINRQI

FTH1

11

P02794
ELQEASQELQQIHQY

APOB

4366

P04114
YNLSQNVQEDDLQHL

ATL1

176

Q8WXF7
DYHDLESVVQQVEQN

ENTR1

316

Q96C92
QLLNDIHQCYLDQRE

COG3

326

Q96JB2
TNHTNEIQDYLQQLT

GLRX

51

P35754
QDHVQNEENYAQVLD

ASAP1

86

Q9ULH1
QAHICQASENDLYLE

DNAAF5

481

Q86Y56
ATDQQQQEEHYRIET

RPRD2

1051

Q5VT52
EQQQAAYCVIQTEHR

SLC13A2

306

Q13183
EHYQALQEESQAQLE

CNTROB

371

Q8N137
TCNQESQDELDHYIN

PHKA2

651

P46019
DLSNLQELYINHNQI

LRRN1

141

Q6UXK5
QATEDVYQLEQQLHS

PKD1

4231

P98161
TNLNQVVRENINCHY

RP1

2081

P56715
HTGRDYQQLCSQQDL

MIOX

226

Q9UGB7
YEAQENHNLIGVANV

KIF13A

781

Q9H1H9
YVEELNRHLNATVNN

RUFY3

266

Q7L099
YQAVQEAVEDRQQHL

UTRN

886

P46939
SVEDEHALIQQYCQT

UTRN

3221

P46939
HNVSLIEEAAQNYQG

TRIM31

126

Q9BZY9
YDQEAQEFNITHLQQ

PUS3

336

Q9BZE2
TAQANVEYNLQQHFE

RBL1

346

P28749
QEADTQIDREHQNFY

ARHGAP42

161

A6NI28
NEVNQNQHDSDTTEY

SSMEM1

136

Q8WWF3
AQRYNTDIHQITENE

RGS20

31

O76081
QDNNTQIEEDTDHNY

PLXDC2

101

Q6UX71
SQDVLRLHQDINDYN

RNF170

146

Q96K19
HTIQNSDDAYVQLDN

SIK3

1216

Q9Y2K2
ENNQNVYGLDDSEHI

SGO2

211

Q562F6
RLQHQTELENQLEYN

TAOK3

676

Q9H2K8
HEVAQDDHLTQQYNE

SEMG2

561

Q02383
YHSDEQNDTQKQFCE

POTEI

591

P0CG38
NHRVEFNVNYTQDLD

NIF3L1

166

Q9GZT8
DSAVQQAALACYHQE

NINL

371

Q9Y2I6
NYNDCIQGALLHQDV

PRORP

246

O15091
HYQERLNSEQSCLNE

SSH3

231

Q8TE77
QYECSLEQALRHVQE

SSH3

431

Q8TE77
QSENDYLQDCLDAIQ

STK32C

416

Q86UX6
AEAVLQNAYQAIHNE

AKAP3

726

O75969
QDEEHCRKVNEYLNN

ADRM1

116

Q16186
INQNVSQSLCQEDDY

APC

1121

P25054
RDTVEFNNHTLCYNN

CMKLR2

176

P46091
CVEISYRAQAEQQHN

CNOT1

1906

A5YKK6
RAEQDQCNLEVHVYN

PWP1

156

Q13610
QCNLEVHVYNQEEDS

PWP1

161

Q13610
DYIQESENIASLHNQ

VPS52

101

Q8N1B4
QLQHDREEFYNQSQE

TSC1

781

Q92574
QDSLQEYLERQHLAQ

NME8

271

Q8N427
LQLSVHQDNNQRQYE

STAG3

251

Q9UJ98
EQLSNDDQALYQNEV

STOX1

711

Q6ZVD7
TNYNSIIQQEATCED

RFX8

126

Q6ZV50
EVLQIEHSYCRQDIN

THAP5

316

Q7Z6K1
QLSLHEDINQRQYEA

STAG3L4

111

Q8TBR4
NELKEYRINHNEFQC

TTC41P

541

Q6P2S7
NEENDCNIALYEHTI

POLR3B

636

Q9NW08
EVNQYANECAEENHP

SPTA1

216

P02549
EANVQFQQYLADLHE

SPTA1

896

P02549
HYQQLLQSLEQGAQE

PLEC

1101

Q15149
LNTNQNHYECIALDK

ZGRF1

741

Q86YA3
DVQQQLNHYQSAALA

ZNF462

2151

Q96JM2
QSHPEQNSVDYCQQL

TFEC

251

O14948
ERNADSLIQNQHYQE

TRPC5

701

Q9UL62
AQEYCHRQQSRTQEN

ZMYM1

31

Q5SVZ6
ENSASCVENNIENIY

TEX15

486

Q9BXT5
ESEQALYEQQQLEAA

ZNF76

376

P36508
ATEAQLYVDQHVQDD

TRPC7

496

Q9HCX4
LVNNLNDAQDIIVYH

VLDLR

681

P98155
SHDEINNYLQQIDQL

GOLGB1

1831

Q14789