Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	metallocarboxypeptidase activity	CPA4 FOLH1 CPA1 FOLH1B AGBL1	1.27e-06	31	124	5	GO:0004181
GeneOntologyMolecularFunction	carboxypeptidase activity	CPA4 FOLH1 CPA1 FOLH1B AGBL1	1.30e-05	49	124	5	GO:0004180
GeneOntologyMolecularFunction	2-acylglycerol-3-phosphate O-acyltransferase activity	LPCAT4 LPCAT2 LPGAT1	1.91e-05	9	124	3	GO:0047144
GeneOntologyMolecularFunction	metallopeptidase activity	CPA4 ADAMTS19 FOLH1 ADAM21 ADAM20 CPA1 FOLH1B AGBL1	3.59e-05	200	124	8	GO:0008237
GeneOntologyMolecularFunction	tetrahydrofolyl-poly(glutamate) polymer binding	FOLH1 FOLH1B	3.83e-05	2	124	2	GO:1904493
GeneOntologyMolecularFunction	Ac-Asp-Glu binding	FOLH1 FOLH1B	3.83e-05	2	124	2	GO:1904492
GeneOntologyMolecularFunction	acylglycerol O-acyltransferase activity	LPCAT4 LPCAT2 DGAT2 LPGAT1	4.45e-05	32	124	4	GO:0016411
GeneOntologyMolecularFunction	metalloexopeptidase activity	CPA4 FOLH1 CPA1 FOLH1B AGBL1	7.46e-05	70	124	5	GO:0008235
GeneOntologyMolecularFunction	1-alkylglycerophosphocholine O-acetyltransferase activity	LPCAT4 LPCAT2	1.14e-04	3	124	2	GO:0047192
GeneOntologyMolecularFunction	1-acylglycerol-3-phosphate O-acyltransferase activity	LPCAT4 LPCAT2 LPGAT1	2.86e-04	21	124	3	GO:0003841
GeneOntologyMolecularFunction	L-lactate dehydrogenase activity	LDHAL6A LDHA	3.78e-04	5	124	2	GO:0004459
GeneOntologyMolecularFunction	inositol 1,3,4,5 tetrakisphosphate binding	ADAP1 ADAP2	3.78e-04	5	124	2	GO:0043533
GeneOntologyMolecularFunction	lysophosphatidic acid acyltransferase activity	LPCAT4 LPCAT2 LPGAT1	4.30e-04	24	124	3	GO:0042171
GeneOntologyMolecularFunction	lysophospholipid acyltransferase activity	LPCAT4 LPCAT2 LPGAT1	4.30e-04	24	124	3	GO:0071617
GeneOntologyMolecularFunction	O-acyltransferase activity	LPCAT4 LPCAT2 DGAT2 LPGAT1	4.95e-04	59	124	4	GO:0008374
GeneOntologyMolecularFunction	lactate dehydrogenase activity	LDHAL6A LDHA	5.65e-04	6	124	2	GO:0004457
GeneOntologyMolecularFunction	exopeptidase activity	CPA4 FOLH1 CPA1 FOLH1B AGBL1	6.20e-04	110	124	5	GO:0008238
GeneOntologyMolecularFunction	peptidase activity	CPA4 USP34 ADAMTS19 FOLH1 ADAM21 ADAM20 CPA1 USP9Y GGT5 USP44 FOLH1B AGBL1	7.76e-04	654	124	12	GO:0008233
GeneOntologyMolecularFunction	1-acylglycerophosphocholine O-acyltransferase activity	LPCAT4 LPCAT2	1.05e-03	8	124	2	GO:0047184
GeneOntologyMolecularFunction	2-acylglycerol O-acyltransferase activity	DGAT2 LPGAT1	1.05e-03	8	124	2	GO:0003846
GeneOntologyMolecularFunction	zinc ion binding	CPA4 CAD DHX58 MBD1 NSD1 CPA1 NR3C1 PTCH1 TRIM10 USP44 MTR APOBEC3C AGBL1 NOS1	1.28e-03	891	124	14	GO:0008270
GeneOntologyMolecularFunction	O-acetyltransferase activity	LPCAT4 LPCAT2	1.34e-03	9	124	2	GO:0016413
GeneOntologyBiologicalProcess	C-terminal protein deglutamylation	FOLH1 FOLH1B AGBL1	4.19e-06	6	124	3	GO:0035609
GeneOntologyBiologicalProcess	protein deglutamylation	FOLH1 FOLH1B AGBL1	1.16e-05	8	124	3	GO:0035608
GeneOntologyBiologicalProcess	peptidyl-glutamic acid modification	TTLL3 FOLH1 FOLH1B AGBL1	2.63e-05	29	124	4	GO:0018200
MousePheno	abnormal peripheral nervous system regeneration	FOLH1 PTPRF FOLH1B NOS1	6.10e-07	11	94	4	MP:0004220
MousePheno	abnormal nervous system regeneration	FOLH1 PTPRF FOLH1B NOS1	1.05e-05	21	94	4	MP:0004858
MousePheno	increased amino acid level	SLC6A18 HNF1A DAO CPA1 SLC25A12 MTR	1.47e-05	79	94	6	MP:0014527
MousePheno	decreased glutamic acid level	FOLH1 DAO FOLH1B	3.41e-05	10	94	3	MP:0030737
MousePheno	abnormal response of heart to induced stress	MYOZ2 EDNRB TRIM10 DYRK1B TIMM50 NOS1	9.13e-05	109	94	6	MP:0004484
MousePheno	abnormal glutamic acid level	FOLH1 DAO FOLH1B	1.26e-04	15	94	3	MP:0030735
MousePheno	abnormal circulating hydroxyproline level	HNF1A CPA1	1.34e-04	3	94	2	MP:0030680
MousePheno	increased circulating hydroxyproline level	HNF1A CPA1	1.34e-04	3	94	2	MP:0030681
Domain	-	ADAP1 PSD ITSN1 APBB1 PLEKHD1 CERT1 NECAP1 PLEKHH1 TBC1D4 ARHGAP21 ADAP2	5.57e-05	391	123	11	2.30.29.30
Domain	PH_dom-like	ADAP1 PSD ITSN1 APBB1 PLEKHD1 CERT1 NECAP1 PLEKHH1 TBC1D4 ARHGAP21 ADAP2	1.19e-04	426	123	11	IPR011993
Domain	PH	ADAP1 PSD ITSN1 PLEKHD1 CERT1 PLEKHH1 ARHGAP21 ADAP2	1.39e-04	229	123	8	PF00169
Domain	Acyltransferase	LPCAT4 LPCAT2 LPGAT1	1.47e-04	16	123	3	PF01553
Domain	PlsC	LPCAT4 LPCAT2 LPGAT1	1.77e-04	17	123	3	SM00563
Domain	Plipid/glycerol_acylTrfase	LPCAT4 LPCAT2 LPGAT1	1.77e-04	17	123	3	IPR002123
Domain	CARBOXYPEPT_ZN_2	CPA4 CPA1 AGBL1	2.50e-04	19	123	3	PS00133
Domain	CARBOXYPEPT_ZN_1	CPA4 CPA1 AGBL1	2.93e-04	20	123	3	PS00132
Domain	UDPGT	UGT2B15 UGT2B17 UGT8	3.40e-04	21	123	3	PF00201
Domain	UDPGT	UGT2B15 UGT2B17 UGT8	3.40e-04	21	123	3	PS00375
Domain	UDP_glucos_trans	UGT2B15 UGT2B17 UGT8	3.40e-04	21	123	3	IPR002213
Domain	L_LDH	LDHAL6A LDHA	4.25e-04	5	123	2	PS00064
Domain	L-lactate_DH	LDHAL6A LDHA	4.25e-04	5	123	2	IPR011304
Domain	L-lactate_DH_AS	LDHAL6A LDHA	4.25e-04	5	123	2	IPR018177
Domain	Peptidase_M14	CPA4 CPA1 AGBL1	4.48e-04	23	123	3	PF00246
Domain	Peptidase_M14	CPA4 CPA1 AGBL1	4.48e-04	23	123	3	IPR000834
Domain	PH	ADAP1 PSD ITSN1 PLEKHD1 CERT1 PLEKHH1 ARHGAP21 ADAP2	5.13e-04	278	123	8	SM00233
Domain	PH_DOMAIN	ADAP1 PSD ITSN1 PLEKHD1 CERT1 PLEKHH1 ARHGAP21 ADAP2	5.25e-04	279	123	8	PS50003
Domain	PH_domain	ADAP1 PSD ITSN1 PLEKHD1 CERT1 PLEKHH1 ARHGAP21 ADAP2	5.37e-04	280	123	8	IPR001849
Domain	TFR_dimer	FOLH1 FOLH1B	6.34e-04	6	123	2	PF04253
Domain	-	FOLH1 FOLH1B	6.34e-04	6	123	2	1.20.930.40
Domain	ADAM_Cys-rich	ADAMTS19 ADAM21 ADAM20	7.26e-04	27	123	3	IPR006586
Domain	ACR	ADAMTS19 ADAM21 ADAM20	7.26e-04	27	123	3	SM00608
Domain	TFR-like_dimer_dom	FOLH1 FOLH1B	8.84e-04	7	123	2	IPR007365
Domain	NAD(P)-bd_dom	FMO5 LDHAL6A MAT2B DAO LDHA PPOX	1.01e-03	173	123	6	IPR016040
Domain	-	CPA4 CPA1	1.17e-03	8	123	2	3.30.70.340
Domain	Lactate/malate_DH_N	LDHAL6A LDHA	1.17e-03	8	123	2	IPR001236
Domain	L-lactate/malate_DH	LDHAL6A LDHA	1.17e-03	8	123	2	IPR001557
Domain	Ldh_1_N	LDHAL6A LDHA	1.17e-03	8	123	2	PF00056
Domain	Propep_M14	CPA4 CPA1	1.17e-03	8	123	2	PF02244
Domain	M14A_act_pep	CPA4 CPA1	1.17e-03	8	123	2	IPR003146
Domain	-	LDHAL6A LDHA	1.50e-03	9	123	2	3.90.110.10
Domain	Lactate/malate_DH_C	LDHAL6A LDHA	1.50e-03	9	123	2	IPR022383
Domain	Ldh_1_C	LDHAL6A LDHA	1.50e-03	9	123	2	PF02866
Domain	Lactate_DH/Glyco_Ohase_4_C	LDHAL6A LDHA	1.50e-03	9	123	2	IPR015955
Domain	Pep_M12B_propep	ADAMTS19 ADAM21 ADAM20	2.14e-03	39	123	3	PF01562
Domain	Peptidase_M12B_N	ADAMTS19 ADAM21 ADAM20	2.14e-03	39	123	3	IPR002870
Domain	GFP-like	STAB2 HMCN1	2.28e-03	11	123	2	IPR023413
Domain	-	STAB2 HMCN1	2.28e-03	11	123	2	2.40.155.10
Domain	DISINTEGRIN_1	ADAMTS19 ADAM21 ADAM20	2.31e-03	40	123	3	PS00427
Domain	Reprolysin	ADAMTS19 ADAM21 ADAM20	2.31e-03	40	123	3	PF01421
Domain	ADAM_MEPRO	ADAMTS19 ADAM21 ADAM20	2.31e-03	40	123	3	PS50215
Domain	DISINTEGRIN_2	ADAMTS19 ADAM21 ADAM20	2.31e-03	40	123	3	PS50214
Domain	Peptidase_M12B	ADAMTS19 ADAM21 ADAM20	2.31e-03	40	123	3	IPR001590
Domain	CYSTEINE_SWITCH	ADAMTS19 ADAM21 ADAM20	2.48e-03	41	123	3	PS00546
Domain	Disintegrin_dom	ADAMTS19 ADAM21 ADAM20	2.48e-03	41	123	3	IPR001762
Domain	Peptidase_M28	FOLH1 FOLH1B	2.72e-03	12	123	2	PF04389
Domain	Peptidase_M28	FOLH1 FOLH1B	2.72e-03	12	123	2	IPR007484
Domain	Pept_M10_metallopeptidase	ADAMTS19 ADAM21 ADAM20	2.84e-03	43	123	3	IPR001818
Domain	Link_dom	STAB2 BCAN	3.20e-03	13	123	2	IPR000538
Domain	Xlink	STAB2 BCAN	3.20e-03	13	123	2	PF00193
Domain	LINK_2	STAB2 BCAN	3.20e-03	13	123	2	PS50963
Domain	LINK	STAB2 BCAN	3.20e-03	13	123	2	SM00445
Domain	LINK_1	STAB2 BCAN	3.20e-03	13	123	2	PS01241
Domain	Disintegrin_CS	ADAM21 ADAM20	4.86e-03	16	123	2	IPR018358
Domain	-	FMO5 LDHAL6A MAT2B LDHA PPOX	5.24e-03	169	123	5	3.40.50.720
Domain	Propept_inh	CPA4 CPA1	5.48e-03	17	123	2	IPR009020
Domain	ATP_grasp_subdomain_1	CAD TTLL3	6.14e-03	18	123	2	IPR013815
Domain	ADAM_CR	ADAM21 ADAM20	6.14e-03	18	123	2	PF08516
Domain	Zn_pept	CPA4 CPA1	6.14e-03	18	123	2	SM00631
Domain	FAD/NAD-binding_dom	FMO5 DAO PPOX	6.30e-03	57	123	3	IPR023753
Pathway	REACTOME_ASPARTATE_AND_ASPARAGINE_METABOLISM	FOLH1 SLC25A12 FOLH1B	8.65e-05	12	106	3	MM15556
Pathway	KEGG_CYSTEINE_AND_METHIONINE_METABOLISM	LDHAL6A MAT2B LDHA MTR	1.18e-04	34	106	4	M10911
Pathway	WP_ONECARBON_METABOLISM	MAT2B FOLH1 MTR FOLH1B	1.18e-04	34	106	4	MM15859
Pubmed	Candidate genes required for embryonic development: a comparative analysis of distal mouse chromosome 14 and human chromosome 13q22.	EDNRB TBC1D4 LMO7	5.08e-07	5	130	3	11829485
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	CCDC8 CAD MAT2B WFS1 ITSN1 APBB1 NR3C1 MRPL39 FAM171A1 IARS2 TSR1 NAT10 TIMM50 MRPS11 MTR MRPL41 PDCL DNA2 HDLBP	2.86e-06	1487	130	19	33957083
Pubmed	A comprehensive resource of interacting protein regions for refining human transcription factor networks.	HNF1A CYBC1 NR3C1 SLC25A12 CAMSAP2 ARHGAP21 MYB	8.07e-06	191	130	7	20195357
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ARMT1 CCDC8 CAD PPP1R12B FAM171A1 GTF2F1 TBC1D4 PTPRF PTPRJ TSR1 NAT10 TIMM50 UTP3 HERC1 HDLBP	9.40e-06	1049	130	15	27880917
Pubmed	Cell cycle-dependent phosphorylation regulates RECQL4 pathway choice and ubiquitination in DNA double-strand break repair.	USP34 CCDC8 CAD MAT2B LDHA NECAP1 MRPL39 FARSA IFT52 TBC1D4 SLC25A12 TSR1 TIMM50 MRPS11 MRPL41 RSL24D1 HDLBP	1.05e-05	1335	130	17	29229926
Pubmed	Regulation of glucose transporter 4 translocation by the Rab guanosine triphosphatase-activating protein AS160/TBC1D4: role of phosphorylation and membrane association.	SLC2A4 TBC1D4	1.39e-05	2	130	2	18801932
Pubmed	Identification of gene structure and subcellular localization of human centaurin alpha 2, and p42IP4, a family of two highly homologous, Ins 1,3,4,5-P4-/PtdIns 3,4,5-P3-binding, adapter proteins.	ADAP1 ADAP2	1.39e-05	2	130	2	14690521
Pubmed	Drosophila Topors is a RING finger-containing protein that functions as a ubiquitin-protein isopeptide ligase for the hairy basic helix-loop-helix repressor protein.	ARL8A ARL8B	1.39e-05	2	130	2	14871887
Pubmed	Rab-GAP TBC1D4 (AS160) is dispensable for the renal control of sodium and water homeostasis but regulates GLUT4 in mouse kidney.	SLC2A4 TBC1D4	1.39e-05	2	130	2	26336159
Pubmed	Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury.	FOLH1 FOLH1B	1.39e-05	2	130	2	25872793
Pubmed	Expression of UDP Glucuronosyltransferases 2B15 and 2B17 is associated with methylation status in prostate cancer cells.	UGT2B15 UGT2B17	1.39e-05	2	130	2	32660355
Pubmed	Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury.	FOLH1 FOLH1B	1.39e-05	2	130	2	27091009
Pubmed	Molecular cloning of a complementary DNA encoding a prostate-specific membrane antigen.	FOLH1 FOLH1B	1.39e-05	2	130	2	8417812
Pubmed	Expression pattern of mouse homolog of prostate-specific membrane antigen (FOLH1) in the transgenic adenocarcinoma of the mouse prostate model.	FOLH1 FOLH1B	1.39e-05	2	130	2	12712410
Pubmed	Calmodulin binds to the Rab GTPase activating protein required for insulin-stimulated GLUT4 translocation.	SLC2A4 TBC1D4	1.39e-05	2	130	2	16055084
Pubmed	The UDP glucuronosyltransferase gene superfamily: suggested nomenclature based on evolutionary divergence.	UGT2B15 UGT2B17	1.39e-05	2	130	2	1909870
Pubmed	Full intracellular retention of GLUT4 requires AS160 Rab GTPase activating protein.	SLC2A4 TBC1D4	1.39e-05	2	130	2	16213228
Pubmed	PDZ-scaffold protein, Tamalin promotes dendritic outgrowth and arborization in rat hippocampal neuron.	PSD TAMALIN	1.39e-05	2	130	2	22569042
Pubmed	Androgen glucuronidation: an unexpected target for androgen deprivation therapy, with prognosis and diagnostic implications.	UGT2B15 UGT2B17	1.39e-05	2	130	2	24121496
Pubmed	Novel associations of UDP-glucuronosyltransferase 2B gene variants with prostate cancer risk in a multiethnic study.	UGT2B15 UGT2B17	1.39e-05	2	130	2	24267955
Pubmed	Differential expression of the androgen-conjugating UGT2B15 and UGT2B17 enzymes in prostate tumor cells during cancer progression.	UGT2B15 UGT2B17	1.39e-05	2	130	2	22170718
Pubmed	Comparative analysis of prostate-specific membrane antigen (PSMA) versus a prostate-specific membrane antigen-like gene.	FOLH1 FOLH1B	1.39e-05	2	130	2	14716746
Pubmed	Identification of centaurin-alpha2: a phosphatidylinositide-binding protein present in fat, heart and skeletal muscle.	ADAP1 ADAP2	1.39e-05	2	130	2	12018390
Pubmed	An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility.	ARL8A ARL8B	1.39e-05	2	130	2	16537643
Pubmed	Detailed genetic mapping around a putative prostate-specific membrane antigen locus on human chromosome 11p11.2.	FOLH1 FOLH1B	1.39e-05	2	130	2	9691167
Pubmed	Presynaptic Biogenesis Requires Axonal Transport of Lysosome-Related Vesicles.	ARL8A ARL8B	1.39e-05	2	130	2	30174114
Pubmed	Localization of UDP glucuronosyltransferase gene(s) on mouse chromosome 5.	UGT2B15 UGT2B17	1.39e-05	2	130	2	3105095
Pubmed	UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells.	UGT2B15 UGT2B17	1.39e-05	2	130	2	17848572
Pubmed	Inhibition of glutamate carboxypeptidase II (GCPII) activity as a treatment for cognitive impairment in multiple sclerosis.	FOLH1 FOLH1B	1.39e-05	2	130	2	23169655
Pubmed	Glutamate carboxypeptidase II and folate deficiencies result in reciprocal protection against cognitive and social deficits in mice: implications for neurodevelopmental disorders.	FOLH1 FOLH1B	1.39e-05	2	130	2	22076974
Pubmed	Deletion of Rab GAP AS160 modifies glucose uptake and GLUT4 translocation in primary skeletal muscles and adipocytes and impairs glucose homeostasis.	SLC2A4 TBC1D4	1.39e-05	2	130	2	23011063
Pubmed	Androgen and Estrogen Receptors in Breast Cancer Coregulate Human UDP-Glucuronosyltransferases 2B15 and 2B17.	UGT2B15 UGT2B17	1.39e-05	2	130	2	27496708
Pubmed	Cloning, expression, genomic localization, and enzymatic activities of the mouse homolog of prostate-specific membrane antigen/NAALADase/folate hydrolase.	FOLH1 FOLH1B	1.39e-05	2	130	2	11210180
Pubmed	Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injury.	FOLH1 FOLH1B	1.39e-05	2	130	2	16190866
Pubmed	Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II.	FOLH1 FOLH1B	1.39e-05	2	130	2	19347959
Pubmed	The uridine diphosphate glucuronosyltransferase 2B15 D85Y and 2B17 deletion polymorphisms predict the glucuronidation pattern of androgens and fat mass in men.	UGT2B15 UGT2B17	1.39e-05	2	130	2	17698910
Pubmed	Grp1 plays a key role in linking insulin signaling to glut4 recycling.	TAMALIN SLC2A4	1.39e-05	2	130	2	22609160
Pubmed	Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate.	FOLH1 FOLH1B	1.39e-05	2	130	2	12358725
Pubmed	GCPII Inhibition Promotes Remyelination after Peripheral Nerve Injury in Aged Mice.	FOLH1 FOLH1B	1.39e-05	2	130	2	39000003
Pubmed	c-Myb interacts with the glucocorticoid receptor and regulates its level in pre-B-acute lymphoblastic leukemia cells.	NR3C1 MYB	1.39e-05	2	130	2	22516378
Pubmed	A novel PSMA/GCPII-deficient mouse model shows enlarged seminal vesicles upon aging.	FOLH1 FOLH1B	1.39e-05	2	130	2	30256431
Pubmed	The Rab GTPase-activating protein TBC1D4/AS160 contains an atypical phosphotyrosine-binding domain that interacts with plasma membrane phospholipids to facilitate GLUT4 trafficking in adipocytes.	SLC2A4 TBC1D4	1.39e-05	2	130	2	23045393
Pubmed	Loss of AS160 Akt substrate causes Glut4 protein to accumulate in compartments that are primed for fusion in basal adipocytes.	SLC2A4 TBC1D4	1.39e-05	2	130	2	21613213
Pubmed	Prostate-specific membrane antigen regulates angiogenesis by modulating integrin signal transduction.	FOLH1 FOLH1B	1.39e-05	2	130	2	16809768
Pubmed	Mouse UDP glucuronosyltransferase. cDNA and complete amino acid sequence and regulation.	UGT2B15 UGT2B17	1.39e-05	2	130	2	3117546
Pubmed	ADAM 20 and 21; two novel human testis-specific membrane metalloproteases with similarity to fertilin-alpha.	ADAM21 ADAM20	1.39e-05	2	130	2	9469942
Pubmed	Metabolite differences between glutamate carboxypeptidase II gene knockout mice and their wild-type littermates after traumatic brain injury: a 7-tesla 1H-MRS study.	FOLH1 FOLH1B	1.39e-05	2	130	2	30458729
Pubmed	Insulin-stimulated phosphorylation of a Rab GTPase-activating protein regulates GLUT4 translocation.	SLC2A4 TBC1D4	1.39e-05	2	130	2	12637568
Pubmed	A role for 14-3-3 in insulin-stimulated GLUT4 translocation through its interaction with the RabGAP AS160.	SLC2A4 TBC1D4	1.39e-05	2	130	2	16880201
Pubmed	Distinguishing Plasmodium falciparum treatment failures from reinfections by restrictions fragment length polymorphism and polymerase chain reaction genotyping.	FOLH1 FOLH1B	1.39e-05	2	130	2	9347959
Pubmed	Early embryonic death of glutamate carboxypeptidase II (NAALADase) homozygous mutants.	FOLH1 FOLH1B	1.39e-05	2	130	2	14556233
Pubmed	Mapping, genomic organization and promoter analysis of the human prostate-specific membrane antigen gene.	FOLH1 FOLH1B	1.39e-05	2	130	2	9838072
Pubmed	Comprehensive Characterization of Mouse UDP-Glucuronosyltransferase (Ugt) Belonging to the Ugt2b Subfamily: Identification of Ugt2b36 as the Predominant Isoform Involved in Morphine Glucuronidation.	UGT2B15 UGT2B17	1.39e-05	2	130	2	28228532
Pubmed	Direct quantification of fusion rate reveals a distal role for AS160 in insulin-stimulated fusion of GLUT4 storage vesicles.	SLC2A4 TBC1D4	1.39e-05	2	130	2	18063571
Pubmed	Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium.	UGT2B15 UGT2B17	1.39e-05	2	130	2	15666817
Pubmed	The glucose transporter 4 FQQI motif is necessary for Akt substrate of 160-kilodalton-dependent plasma membrane translocation but not Golgi-localized (gamma)-ear-containing Arf-binding protein-dependent entry into the insulin-responsive storage compartment.	SLC2A4 TBC1D4	1.39e-05	2	130	2	17761952
Pubmed	Hepatocyte nuclear factor-1alpha regulates glucocorticoid receptor expression to control postnatal body growth.	HNF1A NR3C1	1.39e-05	2	130	2	18583462
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	USP34 CAD ITSN1 NR3C1 FARSA GTF2F1 TBC1D4 LMO7 MTR POTEJ HDLBP	1.39e-05	588	130	11	38580884
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	USP34 CCDC8 CAD PCLAF ARL8A LDHA FARSA TSR1 NAT10 TIMM50 MRPL41 PDCL UTP3 HDLBP	1.74e-05	971	130	14	33306668
Pubmed	The histone acetyltransferase KAT6A is recruited to unmethylated CpG islands via a DNA binding winged helix domain.	MRPL39 GTF2F1 TSR1 NAT10 MRPS11 MRPL41 MRPL34 UTP3 RSL24D1	2.88e-05	417	130	9	36537216
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	EPPK1 MAT2B ITSN1 APBB1 NDUFA8 LDHA FARSA SLC25A12 DYRK1B TIMM50 FKBP3 ARHGAP21 RSL24D1	4.14e-05	916	130	13	32203420
Pubmed	Catalog of 86 single-nucleotide polymorphisms (SNPs) in three uridine diphosphate glycosyltransferase genes: UGT2A1, UGT2B15, and UGT8.	UGT2B15 UGT8	4.15e-05	3	130	2	12376738
Pubmed	Prostate specific membrane antigen (PSMA) regulates angiogenesis independently of VEGF during ocular neovascularization.	FOLH1 FOLH1B	4.15e-05	3	130	2	22815987
Pubmed	AS160 phosphotyrosine-binding domain constructs inhibit insulin-stimulated GLUT4 vesicle fusion with the plasma membrane.	SLC2A4 TBC1D4	4.15e-05	3	130	2	21454690
Pubmed	Copy-number variations (CNVs) of the human sex steroid metabolizing genes UGT2B17 and UGT2B28 and their associations with a UGT2B15 functional polymorphism.	UGT2B15 UGT2B17	4.15e-05	3	130	2	19572376
Pubmed	Abnormal gene expression and regulation in the liver of jvs mice with systemic carnitine deficiency.	HNF1A NR3C1	4.15e-05	3	130	2	7914432
Pubmed	Epigenetic regulation of steroid inactivating UDP-glucuronosyltransferases by microRNAs in prostate cancer.	UGT2B15 UGT2B17	4.15e-05	3	130	2	26385605
Pubmed	Deletion of glutamate carboxypeptidase II (GCPII), but not GCPIII, provided long-term benefits in mice with traumatic brain injury.	FOLH1 FOLH1B	4.15e-05	3	130	2	37349952
Pubmed	Rab10, a target of the AS160 Rab GAP, is required for insulin-stimulated translocation of GLUT4 to the adipocyte plasma membrane.	SLC2A4 TBC1D4	4.15e-05	3	130	2	17403373
Pubmed	Inhibition of GLUT4 translocation by Tbc1d1, a Rab GTPase-activating protein abundant in skeletal muscle, is partially relieved by AMP-activated protein kinase activation.	SLC2A4 TBC1D4	4.15e-05	3	130	2	18258599
Pubmed	Competitive regulation of human intestinal β-carotene 15,15'-monooxygenase 1 (BCMO1) gene expression by hepatocyte nuclear factor (HNF)-1α and HNF-4α.	HNF1A BCO1	4.15e-05	3	130	2	25445224
Pubmed	Characterization of the role of the Rab GTPase-activating protein AS160 in insulin-regulated GLUT4 trafficking.	SLC2A4 TBC1D4	4.15e-05	3	130	2	16154996
Pubmed	Characterization of the substrate specificity of human carboxypeptidase A4 and implications for a role in extracellular peptide processing.	CPA4 CPA1	4.15e-05	3	130	2	20385563
Pubmed	The association of ClipR-59 protein with AS160 modulates AS160 protein phosphorylation and adipocyte Glut4 protein membrane translocation.	SLC2A4 TBC1D4	4.15e-05	3	130	2	22689584
Pubmed	GLUT4 vesicle recruitment and fusion are differentially regulated by Rac, AS160, and Rab8A in muscle cells.	SLC2A4 TBC1D4	4.15e-05	3	130	2	18650435
Pubmed	Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines.	UGT2B15 UGT2B17	4.15e-05	3	130	2	26163549
Pubmed	Forkhead box protein A1 regulates UDP-glucuronosyltransferase 2B15 gene transcription in LNCaP prostate cancer cells.	UGT2B15 UGT2B17	4.15e-05	3	130	2	20736324
Pubmed	Biochemical characterization of human glutamate carboxypeptidase III.	FOLH1 FOLH1B	4.15e-05	3	130	2	17241121
Pubmed	Mammalian acyl-CoA:lysophosphatidylcholine acyltransferase enzymes.	LPCAT4 LPCAT2	4.15e-05	3	130	2	18156367
Pubmed	Molecular evolution of the transferrin receptor/glutamate carboxypeptidase II family.	FOLH1 FOLH1B	4.15e-05	3	130	2	17160644
Pubmed	Genetic variations in UGT2B28, UGT2B17, UGT2B15 genes and the risk of prostate cancer: A case-control study.	UGT2B15 UGT2B17	4.15e-05	3	130	2	28882566
Pubmed	Parallel Metabolomics and Lipidomics of a PSMA/GCPII Deficient Mouse Model Reveal Alteration of NAAG Levels and Brain Lipid Composition.	FOLH1 FOLH1B	4.15e-05	3	130	2	38377674
Pubmed	RUVBL2, a novel AS160-binding protein, regulates insulin-stimulated GLUT4 translocation.	SLC2A4 TBC1D4	4.15e-05	3	130	2	19532121
Pubmed	T cell development critically depends on prethymic stromal patched expression.	NR3C1 PTCH1	4.15e-05	3	130	2	21317383
Pubmed	Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3.	FOLH1 FOLH1B	4.15e-05	3	130	2	21908619
Pubmed	Activators of the farnesoid X receptor negatively regulate androgen glucuronidation in human prostate cancer LNCAP cells.	UGT2B15 UGT2B17	4.15e-05	3	130	2	17988216
Pubmed	Tissue distribution and relative gene expression of UDP-glucuronosyltransferases (2B7, 2B15, 2B17) in the human fetus.	UGT2B15 UGT2B17	4.15e-05	3	130	2	23223495
Pubmed	Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes.	UGT2B15 UGT2B17	4.15e-05	3	130	2	18302198
Pubmed	The nuclear receptor Shp regulates morphine withdrawal syndrome via modulation of Ugt2b expression in mice.	UGT2B15 UGT2B17	4.15e-05	3	130	2	30689982
Pubmed	HAPSTR1 localizes HUWE1 to the nucleus to limit stress signaling pathways.	USP34 CAD ARL8A NDUFA8 LDHA FARSA TBC1D4 TIMM50 MTR PDCL	6.02e-05	571	130	10	37167062
Pubmed	Unbiased Profiling of the Human Proinsulin Biosynthetic Interaction Network Reveals a Role for Peroxiredoxin 4 in Proinsulin Folding.	ARL8A NDUFA8 FARSA IARS2 TSR1 LMO7 MRPS11 LPGAT1 MRPL41	6.57e-05	464	130	9	32457219
Pubmed	The human mitochondrial ribosomal protein genes: mapping of 54 genes to the chromosomes and implications for human disorders.	MRPL39 MRPS11 MRPL41 MRPL34	6.76e-05	58	130	4	11543634
Pubmed	Global phosphoproteome of HT-29 human colon adenocarcinoma cells.	EPPK1 GTF2F1 TBC1D4 LMO7	7.23e-05	59	130	4	16083285
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	CAD EPPK1 EXPH5 LDHA MRPL39 FARSA IARS2 TSR1 LMO7 NAT10 TIMM50 UTP3 UHRF2 FKBP3 HDLBP	7.49e-05	1257	130	15	36526897
Pubmed	Crystal structures of human TBC1D1 and TBC1D4 (AS160) RabGTPase-activating protein (RabGAP) domains reveal critical elements for GLUT4 translocation.	SLC2A4 TBC1D4	8.28e-05	4	130	2	21454505
Pubmed	Rab10 and myosin-Va mediate insulin-stimulated GLUT4 storage vesicle translocation in adipocytes.	SLC2A4 TBC1D4	8.28e-05	4	130	2	22908308
Pubmed	Total homocysteine, B-vitamins and genetic polymorphisms in patients with classical phenylketonuria.	FOLH1 MTR	8.28e-05	4	130	2	18249021
Pubmed	Genetic and environmental influences on total plasma homocysteine and coronary artery disease (CAD) risk among South Indians.	FOLH1 MTR	8.28e-05	4	130	2	19394322
Pubmed	RanBPM, a novel interaction partner of the brain-specific protein p42IP4/centaurin alpha-1.	ADAP1 ADAP2	8.28e-05	4	130	2	18298663
Pubmed	Chromosomal structural variations during progression of a prostate epithelial cell line to a malignant metastatic state inactivate the NF2, NIPSNAP1, UGT2B17, and LPIN2 genes.	LPIN2 UGT2B17	8.28e-05	4	130	2	23792589
Cytoband	14q24.1	ADAM21 ADAM20 PLEKHD1 PLEKHH1	3.00e-06	35	130	4	14q24.1
Cytoband	9q33.2	NDUFA8 OR1Q1 OR1L6 OR1L4	4.67e-06	39	130	4	9q33.2
Cytoband	Ensembl 112 genes in cytogenetic band chr9q33	NDUFA8 OR1Q1 OR1L6 PDCL OR1L4	4.83e-05	138	130	5	chr9q33
Cytoband	13q22.2	TBC1D4 LMO7	2.20e-04	8	130	2	13q22.2
Cytoband	Ensembl 112 genes in cytogenetic band chr13q22	EDNRB TBC1D4 LMO7	7.43e-04	62	130	3	chr13q22
Cytoband	4q13	UGT2B15 UGT2B17	8.16e-04	15	130	2	4q13
Cytoband	7q32	CPA4 CPA1	2.11e-03	24	130	2	7q32
Cytoband	Ensembl 112 genes in cytogenetic band chr14q24	ADAM21 ADAM20 PLEKHD1 PLEKHH1	2.59e-03	200	130	4	chr14q24
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ADAP1 PSD ITSN1 PLEKHD1 CERT1 PLEKHH1 ARHGAP21 ADAP2	6.15e-06	206	86	8	682
GeneFamily	UDP glucuronosyltransferases	UGT2B15 UGT2B17 UGT8	4.66e-04	32	86	3	363
GeneFamily	Mitochondrial ribosomal proteins	MRPL39 MRPS11 MRPL41 MRPL34	5.46e-04	79	86	4	646
GeneFamily	Olfactory receptors, family 1	OR1Q1 OR1L6 OR1L4	9.04e-04	40	86	3	147
GeneFamily	1-acylglycerol-3-phosphate O-acyltransferases	LPCAT4 LPCAT2	1.20e-03	11	86	2	46
GeneFamily	Ubiquitin specific peptidases	USP34 USP9Y USP44	2.40e-03	56	86	3	366
GeneFamily	Protein tyrosine phosphatases, receptor type	PTPRF PTPRJ	4.43e-03	21	86	2	813
GeneFamily	Carboxypeptidases	CPA4 CPA1	4.43e-03	21	86	2	1321
ToppCell	droplet-Heart-nan-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NSD1 NR3C1 CMYA5 TBC1D4 HMCN1 ARHGAP21 HDLBP	8.76e-07	176	130	7	749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 TTLL3 DAO CMYA5 PTCH1 EDNRB TRPM3	1.14e-06	183	130	7	25c96df8ea0c7bbedbb7699ee84ad6234d19cba8
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 TTLL3 DAO CMYA5 PTCH1 EDNRB TRPM3	1.22e-06	185	130	7	dbbd348714cd16a4948a04648e914b1e71e2a8ef
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 TTLL3 DAO CMYA5 PTCH1 EDNRB TRPM3	1.22e-06	185	130	7	bea69058afa5aa927fe15c1f8d46460562ec4dd4
ToppCell	3'-GW_trimst-2-SmallIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPPK1 FMO5 EXPH5 CMYA5 TAMALIN PTPRJ	9.10e-06	165	130	6	34fd00be2b28716c871ad9fb356de84a299a0c01
ToppCell	TCGA-Bile_Duct-Primary_Tumor-Cholangiocarcinoma-Intrahepatic-2\|TCGA-Bile_Duct / Sample_Type by Project: Shred V9	TMEM67 BCAN PTCH1 MTR ARL14EP CAMSAP2	1.01e-05	168	130	6	c70bf73bb800e4722cedc35bbc17ea3113d1012d
ToppCell	facs-Marrow-KLS-24m-Myeloid-promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM3 PCLAF TAMALIN SEMA4C TBC1D4 DNA2	1.04e-05	169	130	6	d6ad3b637de2935c656aad47ad82d6e8a8bd1227
ToppCell	facs-Marrow-KLS-24m-Myeloid-monocyte_+_promonocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CADM3 PCLAF TAMALIN SEMA4C TBC1D4 DNA2	1.04e-05	169	130	6	60ef186518d0dc63dbded2a77c65cfe3129df754
ToppCell	PND01-03-samps-Mesenchymal-Pericyte-pericyte_F\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CPA4 CAD MYOZ2 CPA1 LRRC73 ADAP2	1.08e-05	170	130	6	71718dcebd48105994c313bb55babc70301170a0
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 PTCH1 PTPRJ MTR CAMSAP2 ADAT1	1.49e-05	180	130	6	be10fe5bf7c3a671c42704ce7dd8226ab6896794
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-DN4_thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADAP1 PTCH1 PTPRJ MTR CAMSAP2 ADAT1	1.49e-05	180	130	6	3b747a517ce75ef2ff09011c037dad7b01ed3e03
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR TTLL3 DAO CMYA5 EDNRB GREB1	1.59e-05	182	130	6	904804813849b7f7f716ba1554d33b07bc0a701e
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR TTLL3 DAO CMYA5 EDNRB GREB1	1.59e-05	182	130	6	5d8b7fe18286e27f0f50c5d2d9be56850e2cb8f4
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Epithelial-Bergmann_glial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GABRG1 TTLL3 DAO CMYA5 EDNRB GREB1	1.64e-05	183	130	6	99bb4ceb92f6467f2359a42ab2cff6df18825a30
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FAM171A1 TBC1D4 HMCN1 LMO7 UGT8 NOS1	1.97e-05	189	130	6	f51cdc9a47371cab8ed9ae63a6f14da07ede446c
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-E\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ADAP1 FOLH1 PLEKHH1 FAM171A1 UGT8 ARHGAP21	2.28e-05	194	130	6	cb0422e7607dbd77204428b7e2c70dfe14a6ca11
Disease	mean reticulocyte volume	CAD ITSN1 MBD1 BEND3 TRIM10 IFT52 TBC1D4 PTPRF PTPRJ LPIN2 LPGAT1 ARHGAP21 MYB ADAP2 HDLBP	1.55e-06	799	125	15	EFO_0010701
Disease	Schizoaffective disorder-bipolar type	STAB2 PTCH1 ERCC6L2-AS1	3.99e-05	16	125	3	EFO_0009965
Disease	cholic acid glucuronide measurement	UGT2B15 UGT2B17	5.33e-05	3	125	2	EFO_0800574
Disease	type 2 diabetes mellitus (implicated_via_orthology)	HNF1A NR3C1 SLC2A4 EDNRB MTR	8.66e-05	105	125	5	DOID:9352 (implicated_via_orthology)
Disease	X-25937 measurement	UGT2B15 UGT2B17	1.06e-04	4	125	2	EFO_0800937
Disease	pancreatitis, response to thiopurine	PTCH1 ERCC6L2-AS1	1.06e-04	4	125	2	EFO_0000278, EFO_0006317
Disease	glucagon measurement, glucose tolerance test	UTP3 HERC1	2.64e-04	6	125	2	EFO_0004307, EFO_0008463
Disease	X-24574 measurement	UGT2B15 UGT2B17	3.69e-04	7	125	2	EFO_0800897
Disease	deoxycholic acid glucuronide measurement	UGT2B15 UGT2B17	4.90e-04	8	125	2	EFO_0800575
Disease	cataract (implicated_via_orthology)	WFS1 NR3C1 TRPM3	5.62e-04	38	125	3	DOID:83 (implicated_via_orthology)
Disease	post-traumatic stress disorder (biomarker_via_orthology)	WFS1 NR3C1	6.29e-04	9	125	2	DOID:2055 (biomarker_via_orthology)
Disease	4-androsten-3alpha,17alpha-diol monosulfate (3) measurement	UGT2B15 UGT2B17	7.84e-04	10	125	2	EFO_0022090
Disease	Uterine leiomyoma, estrogen-receptor negative breast cancer	EXPH5 ADAP2	7.84e-04	10	125	2	EFO_1000650, HP_0000131
Disease	DNA repair protein RAD51 homolog 4 measurement	UGT2B15 UGT2B17	9.55e-04	11	125	2	EFO_0801531
Disease	free androgen index	HNF1A NR3C1 PTPRF UGT2B15 UGT2B17 GREB1 ARHGAP21	1.10e-03	374	125	7	EFO_0007005
Disease	5alpha-androstan-3beta,17beta-diol monosulfate (2) measurement	UGT2B15 UGT2B17	1.14e-03	12	125	2	EFO_0800291
Disease	androstenediol (3alpha, 17alpha) monosulfate (3) measurement	UGT2B15 UGT2B17	1.35e-03	13	125	2	EFO_0800293
Disease	X-19141 measurement	UGT2B15 UGT2B17	1.35e-03	13	125	2	EFO_0800799
Disease	cleft lip	CPA4 PCLAF WFS1 NSD1 CCDC168 HDLBP	1.36e-03	284	125	6	EFO_0003959
Disease	5alpha-androstan-3alpha,17alpha-diol monosulfate measurement	UGT2B15 UGT2B17	1.57e-03	14	125	2	EFO_0800283
Disease	behavior	PTCH1 NOS1 ERCC6L2-AS1	1.66e-03	55	125	3	GO_0007610
Disease	chenodeoxycholate measurement	HMCN1 ERCC6L2-AS1	1.80e-03	15	125	2	EFO_0010471
Disease	glycerate measurement	HMCN1 SLC23A2	1.80e-03	15	125	2	EFO_0021029
Disease	smoking behavior, BMI-adjusted waist circumference	NSD1 PTCH1 ADAP2 HDLBP	1.83e-03	122	125	4	EFO_0004318, EFO_0007789
Disease	BMI-adjusted waist circumference, physical activity measurement	NSD1 CPA1 PTCH1 ERCC6L2-AS1	1.89e-03	123	125	4	EFO_0007789, EFO_0008002
Disease	hypertension (implicated_via_orthology)	NR3C1 EDNRB PTPRJ NOS1	2.18e-03	128	125	4	DOID:10763 (implicated_via_orthology)
Disease	free cholesterol measurement, high density lipoprotein cholesterol measurement	HNF1A CERT1 DGAT2 UGT2B15 UGT2B17 HDLBP	2.29e-03	315	125	6	EFO_0004612, EFO_0008591
Disease	HDL cholesterol change measurement, physical activity	HNF1A FOLH1 DGAT2	2.34e-03	62	125	3	EFO_0003940, EFO_0007805
Disease	5alpha-androstan-3alpha,17beta-diol monosulfate (1) measurement	UGT2B15 UGT2B17	2.61e-03	18	125	2	EFO_0800288
Disease	portal hypertension (implicated_via_orthology)	EDNRB NOS1	2.90e-03	19	125	2	DOID:10762 (implicated_via_orthology)
Disease	chemerin measurement	PTCH1 ERCC6L2-AS1	2.90e-03	19	125	2	EFO_0004573
Disease	etiocholanolone glucuronide measurement	UGT2B15 UGT2B17	2.90e-03	19	125	2	EFO_0800362
Disease	venous thromboembolism, fibrinogen measurement	HNF1A PTPRJ HDLBP	2.92e-03	67	125	3	EFO_0004286, EFO_0004623
Disease	androsterone glucuronide measurement	UGT2B15 UGT2B17	3.22e-03	20	125	2	EFO_0800317
Disease	Cleft palate	MBD1 PTCH1 ERCC6L2-AS1	3.44e-03	71	125	3	HP_0000175
Disease	osteoarthritis, hip, osteoarthritis, knee, total joint arthroplasty	PTCH1 ERCC6L2-AS1	3.55e-03	21	125	2	EFO_0004616, EFO_0010726, EFO_1000786
Disease	disease of metabolism (implicated_via_orthology)	LDHAL6A LDHA	3.55e-03	21	125	2	DOID:0014667 (implicated_via_orthology)
Disease	depressive disorder (implicated_via_orthology)	NR3C1 NOS1	3.89e-03	22	125	2	DOID:1596 (implicated_via_orthology)
Disease	X-24947 measurement	UGT2B15 UGT2B17	3.89e-03	22	125	2	EFO_0800910
Disease	alkaline phosphatase measurement	USP34 HNF1A PTCH1 PLEKHD1 SLC2A4 PTPRJ UGT2B15 UGT2B17 ARHGAP21 ERCC6L2-AS1 HDLBP	3.97e-03	1015	125	11	EFO_0004533

Protein segments in the cluster

Peptide	Gene	Start	Entry
RKLTGDRKWEFSVPF	ARMT1	371	Q9H993
RFVEATRKWKVGIPS	ALDH8A1	306	Q9H2A2
LKVISRGRGAKAPGW	ADAM20	46	O43506
LKVISRGRSAKAPGW	ADAM21	46	Q9UKJ8
LSAKFGRQLVPGWKL	ARL14EP	101	Q8N8R7
KFSTGGSKRPAIWID	CPA1	161	P15085
TKLFIRGWGRPEDLK	ABHD18	16	Q0P651
GIKRRSVVSWKTGVF	APOBEC3C	41	Q9NRW3
VLPWGGVFTIKAGRK	C14orf28	26	Q4W4Y0
RAVASWSRIKGIGVP	EDNRB	201	P24530
KTGPKQTEGFRKRWF	ADAP1	261	O75689
RGVQSLWGSLKPKRL	APBB1	691	O00213
VRLKVGSRKPEWGTN	ZNF436-AS1	6	Q8NC38
GSKPAARLTWRKGDQ	CADM3	156	Q8N126
PGGGWTLRRTKELRK	DYRK1B	351	Q9Y463
VKEALLGKPTWIRTG	AGBL1	671	Q96MI9
IRGNRWKAGLTIVTP	ADAP2	321	Q9NPF8
FVPGTQKGVWKLRRD	ADAT1	116	Q9BUB4
AKTWIEKPRGAGLRV	ARHGAP5-AS1	16	Q96IT6
ALGKASSRAGLWPIV	NSD1	2626	Q96L73
VRRGLWEKISAKGPT	ADAMTS19	861	Q8TE59
SWKDTVLGFRKLTPR	DAO	106	P14920
VAWKISGFPKNRVIG	LDHA	146	P00338
SFEGERPGRRSKKIW	BEND3	516	Q5T5X7
TIKIWDIGGQPRFRS	ARL8B	66	Q9NVJ2
TIKLWDIGGQPRFRS	ARL8A	66	Q96BM9
GGWAPASVLRAVAKR	CERT1	586	Q9Y5P4
VLGSPRVKWTFLSRG	BCAN	71	Q96GW7
VIVTVGGFIFWRKKR	PTPRJ	986	Q12913
VWKAVTKTLREPGAG	FAM171A1	16	Q5VUB5
RKWIVLFPEGGFLRK	LPGAT1	176	Q92604
GQRTPFRIGIKESLW	MAT2B	306	Q9NZL9
RRRATSGGKWPQVLF	LPCAT4	186	Q643R3
LTKGPLICWKGSEFR	GREB1	201	Q4ZG55
LEGPARKSLKRLTGW	SLC2A4	236	P14672
FRRKSDLGVGSPDWK	LINC02872	76	A2RU37
SFGTLKKEGWRPRRT	FOLH1	401	Q04609
RLPSRAWKVKLVGEG	HERC1	4506	Q15751
LGPGWKRREVFRKSG	MBD1	11	Q9UIS9
SAVLKIPSAEGRWKA	OR5A1	226	Q8NGJ0
VRSFGTLKKEGWRPR	FOLH1B	91	Q9HBA9
EGFAISAWTPKERRK	KIAA2012	76	Q0VF49
VRRYGKAGSPETKWI	LMO7	1121	Q8WWI1
VKRSLTQGRLWKPSF	EXPH5	1901	Q8NEV8
TKKGRRNRFKWGPAS	HNF1A	196	P20823
KRQAWKLVSGPGTTL	KIF26A	81	Q9ULI4
VIAAVKWAKAIPGFR	NR3C1	571	P04150
PKSGKRHLGKTRWTR	MYB	31	P10242
GTLPRRKGSGFRWKN	TAMALIN	76	Q7Z6J2
RGKKASGDLIPWTVS	NAT10	596	Q9H0A0
RPTPKWQKGIGEFFR	PCLAF	56	Q15004
TPRITWRKDGAVLAG	HMCN1	3741	Q96RW7
WKGTNGTPTKRRAIG	NOS1	721	P29475
GWRRKITQTALKFLG	LPCAT2	101	Q7L5N7
LAFSGVVGIVSWKRP	FAM189B	76	P81408
NGVKLWITAGPREKF	IFT52	51	Q9Y366
GKIWIPDTFFRNSRK	GABRG1	141	Q8N1C3
GRWATQVFKGLKTLP	FMO5	386	P49326
LKFSTGKGVRRPAVW	CPA4	161	Q9UI42
TGWRRGIPAKVATKG	ERCC6L2-AS1	21	Q8WZB0
VKEVFPPWRGALSKG	CMYA5	296	Q8N3K9
LQARGKKRQIGWFPA	ITSN1	1116	Q15811
ALGRLPQKVIWRFSG	UGT8	311	Q16880
PLSFKVGVGKVIRGW	FKBP3	161	Q00688
KRAPGIRSWSLLVGI	CYBC1	16	Q9BQA9
IIWLPTGAGKTRAAA	DHX58	21	Q96C10
LKFAKGQRWRLGDPR	GGT5	326	P36269
GPILGKSWRLYKVFT	GPR156	136	Q8NFN8
GIFWKCARIGERKSP	TMEM167A	41	Q8TBQ9
FGTIRSGKRPEWLFT	CCDC168	5666	Q8NDH2
STEGKRRPAKAWSGR	GPR15L	21	Q6UWK7
GGVWRVISKPATKEA	CCDC8	21	Q9H0W5
IEESIWSPRFGLKGK	DNA2	261	P51530
WSPRFGLKGKIDVTV	DNA2	266	P51530
GRWKKGLTGTQREPI	PIWIL3	381	Q7Z3Z3
AKWAAVRAKAGPTLT	UTP3	11	Q9NQZ2
GWVRPDLGELSKVTK	NDUFA8	116	P51970
DGFIGTWPKEKRSSV	CAMSAP2	421	Q08AD1
VFDWNTPKKGGRRSQ	DGAT2	111	Q96PD7
IKVRAWTSKGSGPLS	PTPRF	986	P10586
NTGPKGVINDWRRFK	PDCL	56	Q13371
LKTAGWKRRIGSPMI	TMEM67	541	Q5HYA8
VLRIPSAAGKWKAFS	OR1L4	226	Q8NGR5
TVLRIPSAAGKWKAF	OR1L6	261	Q8NGR2
LRIPSAKGRWKTFST	OR1Q1	226	Q15612
QPWLLRVNGKSGRKF	GTF2F1	96	P35269
VAPGGGIKWRFIATS	MRPL39	16	Q9NYK5
WTSKRGPRSFRGRKG	MRPL41	21	Q8IXM3
TPRGKRGWKSFHGIL	PSD	776	A5PKW4
LKKWVEVGNSGVFRP	FARSA	426	Q9Y285
TLGKLIYPVGFWRSK	NTHL1	171	P78549
TVGRFRGQKPTLWAL	EPPK1	2111	P58107
ISQKKLRARGVVGFW	MTR	1021	Q99707
PKRKYSVWVGGSILA	POTEJ	996	P0CG39
SKGKATGRKAPLWLR	PTCH1	66	Q13635
PGWQGATKRLLVRSV	IARS2	31	Q9NSE4
GGARTLQRKWTTFLK	SEMA4C	266	Q9C0C4
RLRKGSVGVWTAISP	SLC6A18	81	Q96N87
VRAKVTGKIPAWLQG	BCO1	16	Q9HAY6
KILREEGPSAFWKGT	SLC25A12	566	O75746
RGKPVRLGYKIWCGT	PGBD2	286	Q6P3X8
WRAGKPVRVIRSFKG	UHRF2	556	Q96PU4
LFWAGLRELTKPRGK	PPOX	126	P50336
SRKGWKSKRSPRAAG	TULP4	1426	Q9NRJ4
IPGEESSLRWAGKKF	MRPS11	66	P82912
ATGWRFKKRPGIETL	TIMM50	166	Q3ZCQ8
FKPVELRTKWGRRGH	TSR1	726	Q2NL82
KPVRIFLKGSVAQWS	TICRR	336	Q7Z2Z1
ISPTFVGYTWKGLRK	SLC23A2	621	Q9UGH3
GRPSAKWSRRFFIIK	PLEKHD1	41	A6NEE1
KSRGKICTIGIAPWG	TRPM3	241	Q9HCF6
FLKRWRQGKVLPSEG	SOGA1	681	O94964
PRKVRWTKAFRKAAG	RSL24D1	46	Q9UHA3
PRGKWQGRLTSFISL	STAB2	376	Q8WWQ8
KNKHGWVRRLSTPAG	MRPL34	61	Q9BQ48
DRNIWIVKPGAKSRG	TTLL3	276	Q9Y4R7
RSPKGWLVDLINKFG	USP9Y	216	O00507
LLRGGTKPTVKGWLT	PLEKHH1	681	Q9ULM0
KRTGAPGAFHRWKVV	SLF1	116	Q9BQI6
KEGVPKSRRGEIWQF	TBC1D4	916	O60343
WTPFEGQKVKGTVRR	CAD	1771	P27708
TRKVIPFFGLWGRGS	TRIM10	461	Q9UDY6
SGAWGNKIRPIKASV	HDLBP	61	Q00341
HRKRTWPGKSRKAAG	USP34	1556	Q70CQ2
VLWRFDGKKPNTLGS	UGT2B15	336	P54855
GTWRKGIPSIMRKTF	ARHGAP21	1121	Q5T5U3
IFRTWFEQSPIGRKK	USP44	161	Q9H0E7
VLWRFDGKKPNTLGS	UGT2B17	336	O75795
GRLGSKWPVFELKAI	WFS1	831	O76024
VAWKLSGFPKNRVIG	LDHAL6A	146	Q6ZMR3
WGGFPESTKVSKRER	LPIN2	266	Q92539
GITPKGWSRLAIAVA	LRRC73	156	Q5JTD7
LSGRRSFNRTPKGWI	MYOZ2	226	Q9NPC6
PKERRRGTGINFWTK	PPP1R12B	801	O60237
PDWTGRLRITSKGKT	NECAP1	41	Q8NC96