Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	axon guidance receptor activity	HMCN2 GFRA3 EPHB1	1.72e-05	13	80	3	GO:0008046
Pubmed	ERG and FLI1 protein expression in epithelioid sarcoma.	FLI1 ERG	5.23e-06	2	80	2	24072183
Pubmed	Synergistic Role of Endothelial ERG and FLI1 in Mediating Pulmonary Vascular Homeostasis.	FLI1 ERG	5.23e-06	2	80	2	28248553
Pubmed	The Ets family member Erg gene is expressed in mesodermal tissues and neural crests at fundamental steps during mouse embryogenesis.	FLI1 ERG	5.23e-06	2	80	2	10704859
Pubmed	Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition.	FLI1 ERG	5.23e-06	2	80	2	30500808
Pubmed	Dual requirement for the ETS transcription factors Fli-1 and Erg in hematopoietic stem cells and the megakaryocyte lineage.	FLI1 ERG	5.23e-06	2	80	2	19666492
Pubmed	Transdifferentiation of erythroblasts to megakaryocytes using FLI1 and ERG transcription factors.	FLI1 ERG	5.23e-06	2	80	2	26063314
Pubmed	Allosteric interference in oncogenic FLI1 and ERG transactions by mithramycins.	FLI1 ERG	5.23e-06	2	80	2	33275876
Pubmed	ERG and FLI1 are useful immunohistochemical markers in phosphaturic mesenchymal tumors.	FLI1 ERG	5.23e-06	2	80	2	26122367
Pubmed	Antidiabetic phospholipid-nuclear receptor complex reveals the mechanism for phospholipid-driven gene regulation.	NCOA2 NR0B2	1.57e-05	3	80	2	22504882
Pubmed	FLI1 and ERG protein degradation is regulated via Cathepsin B lysosomal pathway in human dermal microvascular endothelial cells.	FLI1 ERG	1.57e-05	3	80	2	32979864
Pubmed	A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.	FLI1 ERG	1.57e-05	3	80	2	20676125
Pubmed	Current treatment protocols have eliminated the prognostic advantage of type 1 fusions in Ewing sarcoma: a report from the Children's Oncology Group.	FLI1 ERG	1.57e-05	3	80	2	20308669
Pubmed	Impact of EWS-ETS fusion type on disease progression in Ewing's sarcoma/peripheral primitive neuroectodermal tumor: prospective results from the cooperative Euro-E.W.I.N.G. 99 trial.	FLI1 ERG	1.57e-05	3	80	2	20308673
Pubmed	Unexpected Allosteric Network Contributes to LRH-1 Co-regulator Selectivity.	NCOA2 NR0B2	1.57e-05	3	80	2	26553876
Pubmed	Endoglin expression in the endothelium is regulated by Fli-1, Erg, and Elf-1 acting on the promoter and a -8-kb enhancer.	FLI1 ERG	1.57e-05	3	80	2	16484587
Pubmed	A SMARCB1-deficient vulvar neoplasm with prominent myxoid stroma: report of a case showing ERG and FLI1 expression.	FLI1 ERG	1.57e-05	3	80	2	26261664
Pubmed	MCM8IP activates the MCM8-9 helicase to promote DNA synthesis and homologous recombination upon DNA damage.	HROB KANK2 PPP6R3	2.60e-05	25	80	3	32528060
Pubmed	Genome-wide analysis of ETS-family DNA-binding in vitro and in vivo.	FLI1 ERG	3.13e-05	4	80	2	20517297
Pubmed	Necdin, a Prader-Willi syndrome candidate gene, regulates gonadotropin-releasing hormone neurons during development.	MAGEL2 MAGED1	3.13e-05	4	80	2	18930956
Pubmed	The transcription factor Erg is essential for definitive hematopoiesis and the function of adult hematopoietic stem cells.	FLI1 ERG	3.13e-05	4	80	2	18500345
Pubmed	An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.	YTHDF1 EDC3 MAGED1 POLR1A TTLL4 RCN2 ZNF638 SLC6A15 KANK2	4.77e-05	733	80	9	34672954
Pubmed	STK40 Is a Pseudokinase that Binds the E3 Ubiquitin Ligase COP1.	CAMSAP3 RCN2 PPP6R3	5.03e-05	31	80	3	28089446
Pubmed	SIP, a novel ankyrin repeat containing protein, sequesters steroid receptor coactivators in the cytoplasm.	NCOA2 KANK2	5.20e-05	5	80	2	17476305
Pubmed	TRIM8 modulates the EWS/FLI oncoprotein to promote survival in Ewing sarcoma.	FLI1 ERG	5.20e-05	5	80	2	34329586
Pubmed	Mutations in genes encoding the cadherin receptor-ligand pair DCHS1 and FAT4 disrupt cerebral cortical development.	EOMES DCHS1	5.20e-05	5	80	2	24056717
Pubmed	Crystallographic identification and functional characterization of phospholipids as ligands for the orphan nuclear receptor steroidogenic factor-1.	NCOA2 NR0B2	5.20e-05	5	80	2	15721253
Pubmed	An intricate regulatory circuit between FLI1 and GATA1/GATA2/LDB1/ERG dictates erythroid vs. megakaryocytic differentiation.	FLI1 ERG	5.20e-05	5	80	2	38695236
Pubmed	SRC-2-mediated coactivation of anti-tumorigenic target genes suppresses MYC-induced liver cancer.	NCOA2 NR0B2	5.20e-05	5	80	2	28273073
Pubmed	IGF1 is a common target gene of Ewing's sarcoma fusion proteins in mesenchymal progenitor cells.	FLI1 ERG	5.20e-05	5	80	2	18648544
Pubmed	A family of nonclassical class I MHC genes contributes to ultrasensitive chemodetection by mouse vomeronasal sensory neurons.	HLA-F NRP2	5.20e-05	5	80	2	24719092
Pubmed	Regulation of MAGE-A3/6 by the CRL4-DCAF12 ubiquitin ligase and nutrient availability.	PHKB RCN2 DHX9 KPNB1	5.46e-05	89	80	4	31267705
Pubmed	A novel zinc finger gene is fused to EWS in small round cell tumor.	FLI1 ERG	7.79e-05	6	80	2	10949935
Pubmed	Identification of Human Neuronal Protein Complexes Reveals Biochemical Activities and Convergent Mechanisms of Action in Autism Spectrum Disorders.	MAGED1 DCHS1 ACOT7 DHX9	8.94e-05	101	80	4	26949739
Pubmed	Targeted proteomic analysis of 14-3-3 sigma, a p53 effector commonly silenced in cancer.	EDC3 ZNF638 HDAC7 SH3BP4	9.29e-05	102	80	4	15778465
Pubmed	The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages.	EOMES EPHB1	1.09e-04	7	80	2	24038449
Pubmed	Zic2 Controls the Migration of Specific Neuronal Populations in the Developing Forebrain.	EOMES EPHB1	1.09e-04	7	80	2	26269635
Pubmed	Activity of a heptad of transcription factors is associated with stem cell programs and clinical outcome in acute myeloid leukemia.	FLI1 ERG	1.09e-04	7	80	2	23327922
Pubmed	A family of protein-deglutamylating enzymes associated with neurodegeneration.	MYLK TTLL4	1.09e-04	7	80	2	21074048
Pubmed	Erg proteins, transcription factors of the Ets family, form homo, heterodimers and ternary complexes via two distinct domains.	FLI1 ERG	1.45e-04	8	80	2	9681824
Pubmed	Photochemical Identification of Auxiliary Severe Acute Respiratory Syndrome Coronavirus 2 Host Entry Factors Using μMap.	SLC6A15 NRP2	1.45e-04	8	80	2	36049228
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	PHKB HROB EDC3 MTMR14 CAMSAP3 RCN2 KANK2 PPP6R3 KPNB1	1.51e-04	853	80	9	28718761
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	EDC3 MTM1 CAMSAP3 ZNF638 PLEKHA6 PPP6R3 SH3BP4	1.62e-04	503	80	7	16964243
Pubmed	TrkB-dependent EphrinA reverse signaling regulates callosal axon fasciculate growth downstream of Neurod2/6.	SEMA5B NRP2 EPHB1	1.77e-04	47	80	3	35462405
Pubmed	A Genome-wide ER-phagy Screen Highlights Key Roles of Mitochondrial Metabolism and ER-Resident UFMylation.	RCN2 DHX9 KPNB1	1.77e-04	47	80	3	32160526
Pubmed	Discovery of tissue-specific exons using comprehensive human exon microarrays.	RAPGEF1 PLEKHA6	1.86e-04	9	80	2	17456239
Pubmed	Dachsous1-Fat4 Signaling Controls Endothelial Cell Polarization During Lymphatic Valve Morphogenesis-Brief Report.	DCHS1 NRP2	1.86e-04	9	80	2	28705793
Pubmed	Tissue-specific venous expression of the EPH family receptor EphB1 in the skin vasculature.	NRP2 EPHB1	1.86e-04	9	80	2	23649798
Pubmed	Eomesodermin promotes the development of type 1 regulatory T (TR1) cells.	EOMES IL27RA	1.86e-04	9	80	2	28738016
Pubmed	Interactome and Ubiquitinome Analyses Identify Functional Targets of Herpes Simplex Virus 1 Infected Cell Protein 0.	MYLK RCN2 KANK2 DHX9	1.97e-04	124	80	4	35516420
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	YTHDF1 PHKB EDC3 ZNF638 KANK2 NDUFS2	1.98e-04	364	80	6	24778252
Pubmed	A transcriptional inhibitor targeted by the atypical orphan nuclear receptor SHP.	NCOA2 NR0B2	2.32e-04	10	80	2	11964378
Pubmed	Dab1 contributes differently to the morphogenesis of the hippocampal subdivisions.	EOMES EPHB1	2.32e-04	10	80	2	28945921
Pubmed	Ephrin-B2 paces neuronal production in the developing neocortex.	EOMES EPHB1	2.32e-04	10	80	2	32404061
Pubmed	The cytokines interleukin 27 and interferon-γ promote distinct Treg cell populations required to limit infection-induced pathology.	EOMES IL27RA	2.32e-04	10	80	2	22981537
Pubmed	KSHV Viral Protein Kinase Interacts with USP9X to Modulate the Viral Lifecycle.	RCN2 PPP6R3	2.32e-04	10	80	2	36995092
Pubmed	A novel cell migratory zone in the developing hippocampal formation.	EOMES EPHB1	2.32e-04	10	80	2	24771490
Pubmed	Heterozygous deletion of chromosome 17p renders prostate cancer vulnerable to inhibition of RNA polymerase II.	YTHDF1 MAGED1 RCN2 BTAF1 DHX9	2.56e-04	244	80	5	30349055
Pubmed	Bidirectional ephrinB3/EphA4 signaling mediates the segregation of medial ganglionic eminence- and preoptic area-derived interneurons in the deep and superficial migratory stream.	NRP2 EPHB1	2.84e-04	11	80	2	22171039
Pubmed	Necdin promotes ubiquitin-dependent degradation of PIAS1 SUMO E3 ligase.	MAGEL2 MAGED1	2.84e-04	11	80	2	24911587
Pubmed	The Hippocampal Response to Acute Corticosterone Elevation Is Altered in a Mouse Model for Angelman Syndrome.	NCOA2 NR0B2	2.84e-04	11	80	2	36613751
Pubmed	Adrenocorticotropic hormone-mediated signaling cascades coordinate a cyclic pattern of steroidogenic factor 1-dependent transcriptional activation.	NCOA2 HDAC7	2.84e-04	11	80	2	16109736
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	PHKB MAGED1 POLR1A KANK2 HDAC7 SH3BP4	3.27e-04	400	80	6	35013556
Pubmed	A balance of noncanonical Semaphorin signaling from the cerebrospinal fluid regulates apical cell dynamics during corticogenesis.	EOMES NRP2	3.40e-04	12	80	2	36399562
Pubmed	Cdx2 is required for correct cell fate specification and differentiation of trophectoderm in the mouse blastocyst.	EOMES ITGA7	3.40e-04	12	80	2	15788452
Pubmed	Cellular proteins and HIV-1 Rev function.	DHX9 KPNB1	3.40e-04	12	80	2	19149558
Pubmed	Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors.	EOMES ITGA7 KPNB1	3.83e-04	61	80	3	19796622
Pubmed	In silico APC/C substrate discovery reveals cell cycle-dependent degradation of UHRF1 and other chromatin regulators.	YTHDF1 CCDC137 MAGED1 RCN2 BTAF1 NDUFS2 PPP6R3 DHX9 KPNB1	3.91e-04	971	80	9	33306668
Pubmed	Jagged1 is Essential for Radial Glial Maintenance in the Cortical Proliferative Zone.	EOMES JAG2	4.01e-04	13	80	2	31202705
Pubmed	MED12 Regulates HSC-Specific Enhancers Independently of Mediator Kinase Activity to Control Hematopoiesis.	FLI1 ERG	4.01e-04	13	80	2	27570068
Pubmed	Induction of hematopoietic and endothelial cell program orchestrated by ETS transcription factor ER71/ETV2.	FLI1 ERG	4.01e-04	13	80	2	25802403
Pubmed	The Transcription Factor Prdm16 Marks a Single Retinal Ganglion Cell Subtype in the Mouse Retina.	EOMES ERG	4.01e-04	13	80	2	29053761
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	ERG CAMSAP3 FNBP4 ZNF638 BTAF1 HDAC7 PPP6R3 DHX9	4.10e-04	774	80	8	15302935
Pubmed	The doublesex homolog Dmrt5 is required for the development of the caudomedial cerebral cortex in mammals.	EOMES NRP2 EPHB1	4.21e-04	63	80	3	22923088
Pubmed	The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.	PAOX ACP6 DNHD1 SUSD4 SEMA5B NBEAL2 ITGA7 GFRA3 IL27RA	4.34e-04	985	80	9	12975309
Pubmed	The paired box transcription factor Pax8 is essential for function and survival of adult thyroid cells.	CA3 TG	4.67e-04	14	80	2	25127920
Pubmed	Cyclin D-cdk4 activity modulates the subnuclear localization and interaction of MEF2 with SRC-family coactivators during skeletal muscle differentiation.	NCOA2 HDAC7	4.67e-04	14	80	2	12130539
Pubmed	Ephrin B1 maintains apical adhesion of neural progenitors.	EOMES EPHB1	4.67e-04	14	80	2	23578932
Pubmed	Targeted ubiquitination and degradation of G-protein-coupled receptor kinase 5 by the DDB1-CUL4 ubiquitin ligase complex.	KANK2 PPP6R3 DHX9 KPNB1	4.73e-04	156	80	4	22952844
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	MAGEL2 MAGED1 SPATA31E1 TEX14 KPNB1 SH3BP4	4.79e-04	430	80	6	35044719
Pubmed	C3G/Rapgef1 Is Required in Multipolar Neurons for the Transition to a Bipolar Morphology during Cortical Development.	EOMES RAPGEF1	5.38e-04	15	80	2	27111087
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	JAG2 NCOA2 PHKB POLR1A BCAS3 CAMSAP3 FNBP4 ZNF638 BTAF1 KRCC1 SH3BP4	5.93e-04	1489	80	11	28611215
Pubmed	PHF6-mediated transcriptional control of NSC via Ephrin receptors is impaired in the intellectual disability syndrome BFLS.	EOMES EPHB1	6.14e-04	16	80	2	38429579
Pubmed	Histone Deacetylase 3 Coordinates Deacetylase-independent Epigenetic Silencing of Transforming Growth Factor-β1 (TGF-β1) to Orchestrate Second Heart Field Development.	NRP2 KPNB1	6.14e-04	16	80	2	26420484
Pubmed	Fli1 acts downstream of Etv2 to govern cell survival and vascular homeostasis via positive autoregulation.	FLI1 ERG	6.14e-04	16	80	2	24727028
Pubmed	Local network topology in human protein interaction data predicts functional association.	NCOA2 NR0B2	6.14e-04	16	80	2	19641626
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	YTHDF1 HROB EDC3 MTMR14 BCAS3 TTLL4 PLEKHA6 KANK2 PPP6R3	6.32e-04	1038	80	9	26673895
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	PHKB MTMR14 MTM1 CAMSAP3 RCN2 ZNF638 SLC6A15 PPP6R3 KPNB1	6.81e-04	1049	80	9	27880917
Pubmed	LGALS3BP regulates centriole biogenesis and centrosome hypertrophy in cancer cells.	YTHDF1 PHKB MAGED1 RCN2 UBXN2A PPP6R3 DHX9	6.82e-04	639	80	7	23443559
Pubmed	Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals.	ERG NRP2	6.95e-04	17	80	2	35079138
Pubmed	The BMP antagonist gremlin 1 contributes to the development of cortical excitatory neurons, motor balance and fear responses.	EOMES RYR3	6.95e-04	17	80	2	34184027
Pubmed	Effect of canonical Wnt inhibition in the neurogenic cortex, hippocampus, and premigratory dentate gyrus progenitor pool.	EOMES NRP2	6.95e-04	17	80	2	18521945
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	YTHDF1 CCDC137 POLR1A FNBP4 ZNF638 KANK2 DHX9 KPNB1	7.40e-04	847	80	8	35850772
Pubmed	MTHFR and MSX1 contribute to the risk of nonsyndromic cleft lip/palate.	TBX22 JAG2	7.81e-04	18	80	2	20572854
Pubmed	Cerebral Cortex Expression of Gli3 Is Required for Normal Development of the Lateral Olfactory Tract.	EOMES NRP2	7.81e-04	18	80	2	26509897
Pubmed	An overview of the MAGE gene family with the identification of all human members of the family.	MAGEL2 MAGED1	7.81e-04	18	80	2	11454705
Pubmed	Development of a diagnostic genetic test for simplex and autosomal recessive retinitis pigmentosa.	USH2A CNGB1	7.81e-04	18	80	2	20591486
Pubmed	Combinatorial transcriptional control in blood stem/progenitor cells: genome-wide analysis of ten major transcriptional regulators.	FLI1 ERG	7.81e-04	18	80	2	20887958
Pubmed	Timing specific requirement of microRNA function is essential for embryonic and postnatal hippocampal development.	EOMES NRP2	7.81e-04	18	80	2	21991391
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	CAMSAP3 SLC6A15 BTAF1 NDUFS2 PPP6R3 DHX9 KPNB1	8.02e-04	657	80	7	36180527
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	YTHDF1 MAGED1 ZNF638 KANK2 KPNB1	8.15e-04	315	80	5	26777405
Interaction	ST8SIA3 interactions	YTHDF1 HLA-F NMU NRP2	3.96e-06	28	78	4	int:ST8SIA3
Interaction	MAGEA3 interactions	PHKB KIF27 RCN2 ACOT7 DHX9 KPNB1	1.34e-05	134	78	6	int:MAGEA3
Cytoband	11p15.4	DNHD1 TRIM66 DCHS1 TRIM68	4.27e-04	200	80	4	11p15.4
Cytoband	Xq21.1	TBX22 SATL1	1.53e-03	33	80	2	Xq21.1
GeneFamily	Myotubularins\|Phosphoinositide phosphatases	MTMR14 MTM1	8.32e-04	15	52	2	903
GeneFamily	Fibronectin type III domain containing	MYLK USH2A IL27RA EPHB1	1.15e-03	160	52	4	555
GeneFamily	T-boxes	EOMES TBX22	1.21e-03	18	52	2	766
GeneFamily	ETS transcription factor family	FLI1 ERG	2.92e-03	28	52	2	534
GeneFamily	Phosphoinositide phosphatases	MTMR14 MTM1	3.81e-03	32	52	2	1079
ToppCell	nucseq\|World / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NCOA2 BCAS3 RAPGEF1 PLEKHA6 PPP6R3 TG	1.33e-06	193	80	6	779276e775cb2492e8dd36436295a536084a6415
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 HMCN2 ERG RAPGEF1	1.24e-05	166	80	5	8e2faca6a2e76a625de04d6098aa6f98911945c6
ToppCell	facs-Heart-RA-18m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 ERG RAPGEF1 NRP2	2.31e-05	189	80	5	1be5067c1e45af7d09c1fd6955952cb9e031a3a0
ToppCell	facs-Heart-RA-18m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 ERG RAPGEF1 NRP2	2.31e-05	189	80	5	30dc1725d43a60017fb12d706f1f85a33de4947e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-endothelial_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 ERG RAPGEF1 NRP2	2.37e-05	190	80	5	38a815abf0ac5cac6071737cadc54a514f62d37d
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 ERG RAPGEF1 NRP2	2.37e-05	190	80	5	bb1476b44dd49e1dd52a636a91c4600b6d4fbe2e
ToppCell	facs-Limb_Muscle-ForelimbandHindlimb-3m-Endothelial-nan\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 ERG RAPGEF1 NRP2	2.37e-05	190	80	5	d180205c70b5ca9bc5a01a2e6cb42fcebc7f630d
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 ERG RAPGEF1 RYR3	2.43e-05	191	80	5	b2c86cde341fe350143658c8a8a4a9edbce3f19b
ToppCell	facs-Heart-LA-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ERG RAPGEF1 NRP2 EPHB1	2.43e-05	191	80	5	a15f0fb4bd7dd77ef5f931b6fc9d68697deec1d1
ToppCell	facs-Heart-LA-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ERG RAPGEF1 NRP2 EPHB1	2.43e-05	191	80	5	827be47d3574c6c5b021c6f1c1670834344f10cb
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 IFIT2 NRP2	2.49e-05	192	80	5	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 IFIT2 NRP2	2.49e-05	192	80	5	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 HMCN2 ERG RAPGEF1	2.49e-05	192	80	5	3259cb89d6bcf0a3c6ff1f64d85e8a1f54124e91
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 IFIT2 NRP2	2.49e-05	192	80	5	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	5'-GW_trimst-2-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HMCN2 MYLK KANK2 RYR3 NRP2	2.55e-05	193	80	5	0256e8fe4a47f2e2a43ef9d19bfc047d20806d69
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 HMCN2 ERG RAPGEF1	2.68e-05	195	80	5	6bdef651cf73d7381e5012d0eb3c809138fb6b92
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 HMCN2 ERG RAPGEF1	2.68e-05	195	80	5	d35102f95bb1e419d2df05ff0a01b6c5c923acef
ToppCell	facs-Heart-RA-18m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ERG RAPGEF1 HDAC7 NRP2	2.68e-05	195	80	5	30c75761079fa1e1a3b84d23c88a222f459d5ce5
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG MYLK ITGA7 KANK2 NRP2	2.75e-05	196	80	5	fa445f4240c521cf04eb2e2f79a5c55fda31209a
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Myocytic_interstitial_cell-Myofibroblast\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ERG MYLK ITGA7 KANK2 NRP2	2.75e-05	196	80	5	802f61e78a9a1030a86c4a980c398a73cd4d1574
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_IT-L6_IT_ALM_Oprk1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	IQANK1 KIF27 USH2A	8.30e-05	47	80	3	b83e9a0f8db3f1581c5621f9d835ae2423ba0978
ToppCell	Children_(3_yrs)-Immune-mast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EFHC2 ERG GFRA3 RYR3	1.39e-04	146	80	4	f7349d63bb47f1f22ced8ff514edc1c11bc782e7
ToppCell	Cerebellum\|World / BrainAtlas - Mouse McCarroll V32	EOMES KANK2 NR0B2 NDUFS2	1.43e-04	147	80	4	dd730224e39571ca2c35042e242a908a02ee377d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	EOMES EFHC2 EDC3 IFIT2	1.58e-04	151	80	4	def98dc2a8226295b62de2b7f1b587e03a4f038c
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Krt80_Sla\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	ITGA7 RYR3 SH3BP4 EPHB1	1.58e-04	151	80	4	f50c5ae9dae507df750df25e151b58685fec70ce
ToppCell	COVID-19-Heart-Adipocyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HMCN2 SATL1 ITGA7 RYR3	1.66e-04	153	80	4	93958bd9c951222ba5b740d1cb83fd5d78a10e1e
ToppCell	Children_(3_yrs)-Immune-mast_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EFHC2 ERG GFRA3 RYR3	1.84e-04	157	80	4	ec185dbeabb67fd9ca85f71cab88463b60f9b1c1
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-mature_NK_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHKB MTM1 TEX14 RYR3	1.93e-04	159	80	4	4000ed0d3b7d488722bcd0042fa2ff4405aaab82
ToppCell	facs-Lung-Endomucin-24m-Lymphocytic-Natural_Killer_T_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHKB MTM1 TEX14 RYR3	1.93e-04	159	80	4	7619d0d49738dd08daf01b42664691a5323aa793
ToppCell	URO-Lymphocyte-T_NK-MAIT\|URO / Disease, Lineage and Cell Type	EOMES ACP6 CPT1C NMU	2.17e-04	164	80	4	cb42a70433b3968caca67f7aa98ea536cd90a0bc
ToppCell	356C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EFHC2 ERG PAK6 GFRA3	2.17e-04	164	80	4	b3192c443f4848e6a8afdb89c155f9ec42a154b0
ToppCell	356C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	EFHC2 ERG PAK6 GFRA3	2.17e-04	164	80	4	f7288ec4daf494dae770ea6c58bead27660ccae1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 HROB HMCN2 ERG	2.22e-04	165	80	4	a74751e0ec857aa974bec04ccc747c004a8f6e01
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l22\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PHKB MTM1 TEX14 RYR3	2.27e-04	166	80	4	bcdaab49bde5beba750b76fdcc3781a3c12c4fff
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-mature_NK_T_cell\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PHKB MTM1 TEX14 RYR3	2.27e-04	166	80	4	5e3b998d740b24f790fad37350d704ca0ea10b77
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	HMCN2 ERG MYLK ITGA7	2.32e-04	167	80	4	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 HROB HMCN2 ERG	2.43e-04	169	80	4	c7fc3a8c44f07c557b60d469717b66e2f5863d38
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SUSD4 IL27RA NRP2 EPHB1	2.49e-04	170	80	4	35e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SUSD4 IL27RA NRP2 EPHB1	2.49e-04	170	80	4	0ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SUSD4 IL27RA NRP2 EPHB1	2.49e-04	170	80	4	0b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK ITGA7 NR0B2 TG	2.54e-04	171	80	4	b54d9d6b03c9c6f28a71cf2ed2bfa9a335bba949
ToppCell	facs-Heart-RA-18m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK ITGA7 NR0B2 TG	2.54e-04	171	80	4	9d825a2e799421af4f2cf4f4dc8e239b5d00476d
ToppCell	10x5'-GI_small-bowel-Lymphocytic_NK-NK_CD16\|GI_small-bowel / Manually curated celltypes from each tissue	EOMES EFHC2 CPT1C EPHB1	2.54e-04	171	80	4	1ee505b91f15191d294a5d491ecdf154c08b8622
ToppCell	390C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	MAGED1 MTM1 SH3BP4 EPHB1	2.60e-04	172	80	4	3f894c74916d49a995b2d4651ca1c6733c14ce9c
ToppCell	Immune-mast_cell\|World / Lineage, Cell type, age group and donor	EFHC2 FLI1 ERG RYR3	2.60e-04	172	80	4	6e8e0aac5a20dbc789bf8c6916833bb8709a411a
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	JAG2 EFHC2 ERG RYR3	2.60e-04	172	80	4	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a6.Nell1_(Neuron.Slc17a6.Nell1)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KLHDC7B FAM187A GFRA3	2.61e-04	69	80	3	11e6747ed4a45acee210c48ba670bfe0375fb19b
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a6.Nell1_(Neuron.Slc17a6.Nell1)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	KLHDC7B FAM187A GFRA3	2.61e-04	69	80	3	96564b46008a6e5220b6596cbbe0a24e9b5955ee
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-M/X_cells_(MLN/GHRL+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CROCC2 ACOT7 NR0B2 GFRA3	2.72e-04	174	80	4	d22b73b5aed85fb09fbe039f64504e19ebf9acb8
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Macrophage-macrophage,_alveolar-Macro_c1-C1QC\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ACP6 TRIM66 KLHDC7B NRP2	2.72e-04	174	80	4	d77fa525d5c87c190b4a10787b270eabd16c610f
ToppCell	5'-GW_trimst-2-LymphNode-Endothelial-blood_vessel_EC-Fetal_venous_EC\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EFHC2 FLI1 ERG TG	2.72e-04	174	80	4	6b5ff1cc5fe6705f7ea70b5a892dfbf91e32288d
ToppCell	NS-control-d_0-4-Myeloid-Mast_cell\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLI1 ERG IGFLR1 GFRA3	2.72e-04	174	80	4	2d1f5c17b1551f32f49618ec1bf68eafbfd02ace
ToppCell	Monocytes-IFN-activated_Monocytes\|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	ERG KLHDC7B USH2A IFIT2	2.84e-04	176	80	4	6a4b403ee3e4dc4f23fbd7a154011e41fd429a9e
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SUSD4 IL27RA NRP2 EPHB1	2.84e-04	176	80	4	a9e77681bcd36c382d53eb6f771349d55f98d744
ToppCell	droplet-Spleen-SPLEEN-30m-Lymphocytic-mature_NK_T_cell\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EOMES NBEAL2 ACOT7 PAK6	2.90e-04	177	80	4	52402ff6299210c46fd9dee3cef203c0eda7a98a
ToppCell	356C-Lymphocytic-CD4_T-cell-Treg_cell_1\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	HROB EDC3 KIF27 KLHDC7B	2.90e-04	177	80	4	36b5d29caa9cffbc0284f771a4db71aa72171a89
ToppCell	facs-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l9\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	EOMES ACOT7 IGFLR1 IL27RA	2.90e-04	177	80	4	d6b7d387e7485ff52ce27f51df8b8050f49fd941
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SUSD4 ERG HLA-F NRP2	2.96e-04	178	80	4	4ef6344d0ffc9c55b1240bee94b741382f1427bb
ToppCell	3'-GW_trimst-1-LargeIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SUSD4 ERG HLA-F NRP2	2.96e-04	178	80	4	c65932cbedbbfacb6f0299280663fe7c88dba72b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC2_(MADCAM1+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERG HLA-F NRP2 EPHB1	3.03e-04	179	80	4	dfd5b25f2a6a5a8bf4714f1516cb0997de72b06f
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JAG2 FLI1 ERG RAPGEF1	3.03e-04	179	80	4	1ce8d18f63e8dd2d3db41fbeca4601bd3b305fba
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	FLI1 ERG CROCC2 DCHS1	3.03e-04	179	80	4	8f9e538c822940785130297712b75131812a4603
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	JAG2 FLI1 ERG RAPGEF1	3.03e-04	179	80	4	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SUSD4 SEMA5B BCAS3 ITGA7	3.09e-04	180	80	4	4fb95ed39508bede5472dd36aeabe91b33631726
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ERG NRP2 EPHB1	3.22e-04	182	80	4	3b4dbf61ca0fe50efe05449815630e301cb76630
ToppCell	droplet-Pancreas-Exocrine-18m-Endothelial-endothelial_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLI1 ERG NRP2 EPHB1	3.22e-04	182	80	4	ab5761bf9af439231cd0f487b6467e372672a517
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	PIGQ ERG KANK2 CA3	3.29e-04	183	80	4	1db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCell	Mesenchymal_cells-Osteoblasts\|Mesenchymal_cells / Lineage and Cell class	MAGED1 CA3 NRP2 TG	3.29e-04	183	80	4	d6b52d52fe9a7a6c798947f05420d79fe12e4662
ToppCell	3'_v3-lymph-node_spleen-Mast\|lymph-node_spleen / Manually curated celltypes from each tissue	ERG ACOT7 GFRA3 RYR3	3.36e-04	184	80	4	83675c7a083c52fb74dc8b9d35df0ef69715f707
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACOT7 PAK6 IGFLR1 IL27RA	3.36e-04	184	80	4	8fc047977fad38fcd26eebcc279a688efd342ed8
ToppCell	3'_v3-lymph-node_spleen-Mast-Mast_cells\|lymph-node_spleen / Manually curated celltypes from each tissue	ERG ACOT7 GFRA3 RYR3	3.36e-04	184	80	4	ed266bd2d12f86e8786473e64fbcd58319cd4c2a
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 SUSD4 ERG IFIT2	3.43e-04	185	80	4	808d5e880069aff8866cd2c733b9fe568a37701f
ToppCell	3'-GW_trimst-1-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ERG HLA-F NRP2 EPHB1	3.43e-04	185	80	4	fb84fcf7f51f53489bcb3962fa9cb483e48257ed
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG CPT1C DCHS1 HDAC7	3.50e-04	186	80	4	2cae34336f184f971f7c8684cc27c23a4e7369ed
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG CPT1C DCHS1 HDAC7	3.50e-04	186	80	4	90d53c2597a9f3a2b39afba75adfc54f1ca0a4db
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Alv_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 SUSD4 ERG IFIT2	3.57e-04	187	80	4	f3397dbc23b6c2f24e2c1ba887d8f9aef3ee01a1
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	JAG2 FLI1 ERG RAPGEF1	3.57e-04	187	80	4	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	facs-Heart-LV-3m\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 NRP2	3.57e-04	187	80	4	1bc338c22d645a854f8d8eb8a064c441121fb673
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Activated_Gen_Cap\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 SUSD4 ERG IFIT2	3.57e-04	187	80	4	dffa8447c2f3fdacf39a7258c6b4e81a25245041
ToppCell	wk_08-11-Endothelial-Blood_vessel_endothelial-GRIA2+_arterial_endo\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	JAG2 FLI1 ERG IL27RA	3.57e-04	187	80	4	a27aa97aa6508a3ffe92c2b6bb0511a95650a390
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 SUSD4 ERG IFIT2	3.64e-04	188	80	4	789d1be574e693d7bdd488f3c72c6df788e47b47
ToppCell	Fetal_29-31_weeks-Mesenchymal-airway_smooth_muscle_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	HMCN2 MYLK DCHS1 ITGA7	3.64e-04	188	80	4	c29aaae3c5bb7cd6b9b3defd4d27afde3af19ba0
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 MYLK ITGA7 KANK2	3.64e-04	188	80	4	d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 ERG RAPGEF1	3.64e-04	188	80	4	c2c51c6526defe2600302901159b8abbb58d7595
ToppCell	COVID_vent-Myeloid-Monocytic-SC_&_Eosinophil\|COVID_vent / Disease condition, Lineage, Cell class and subclass	EFHC2 ERG RYR3 SH3BP4	3.72e-04	189	80	4	2157a2d40613f7d5ce2e7dbd266df441e449cdaf
ToppCell	facs-Heart-LV-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 NRP2	3.72e-04	189	80	4	d424d2554595b2304219f7324406b401711af7c2
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	JAG2 FLI1 HMCN2 ERG	3.72e-04	189	80	4	6463890d8dbee4bc198f91628a5f784970de786a
ToppCell	droplet-Liver-Hepatocytes-24m-Endothelial-endothelial_cell_of_hepatic_sinusoid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ERG CPT1C DCHS1 HDAC7	3.72e-04	189	80	4	ce5b3d53c9a5457a5a02b221dee18334b5eaf8b7
ToppCell	facs-Heart-LV-3m-Endothelial-endothelial_cell_of_coronary_artery\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 NRP2	3.72e-04	189	80	4	393ec5954a12d6cf67bb435dcc34ff0b14c81e9f
ToppCell	facs-Heart-LV-3m-Endothelial-coronary_vascular_endothelial_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	JAG2 FLI1 RAPGEF1 NRP2	3.72e-04	189	80	4	bec57459ad4bab15b2532b57722549fec2e771fb
ToppCell	COVID-19-kidney-AQP1+SLC14A1+EC\|kidney / Disease (COVID-19 only), tissue and cell type	JAG2 FLI1 ERG RAPGEF1	3.79e-04	190	80	4	1519f34d31fe0817184c5865a0bc9f0cb479b1a4
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FLI1 SUSD4 ERG IFIT2	3.79e-04	190	80	4	a3c6eec6df052105ab78b7e3c78f94218d5912eb
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	FLI1 ERG MYLK RAPGEF1	3.79e-04	190	80	4	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	(5)_Fibroblasts-(5)_Fibroblast-I\|(5)_Fibroblasts / Lung cell shreds - cell class (v4) and cell subclass (v4)	CCDC137 ACOT7 CNGB1 NR0B2	3.79e-04	190	80	4	59ce52a0bb8e5ffbed2622ba7b4343501d1b2abf
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-smooth_muscle_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK SEMA5B BCAS3 ITGA7	3.87e-04	191	80	4	5c1f5b6c115b1b27b4a7467a6550ce43c01cf6d0
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell-neuroendocrine\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYLK BCAS3 ITGA7 GFRA3	3.87e-04	191	80	4	72f1ddc09080dbfea8d51294cbf7f9d4925f9cc0
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SUSD4 MYLK NRP2 EPHB1	3.87e-04	191	80	4	51cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCell	droplet-Trachea-3m-Epithelial-airway_epithelial-neuroendocrine_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYLK BCAS3 ITGA7 GFRA3	3.87e-04	191	80	4	6e7f589efc997f32175e0789c5ea7ca46e1389b8
ToppCell	droplet-Trachea-nan-3m-Epithelial-neuroendocrine_cell\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYLK BCAS3 ITGA7 GFRA3	3.87e-04	191	80	4	3ce403e0beedb544edeb3ae6eb30267040d00c21
ToppCell	droplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SUSD4 MYLK NRP2 EPHB1	3.87e-04	191	80	4	a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
Drug	Benzathine benzylpenicillin [5928-84-7]; Up 200; 4.2uM; MCF7; HT_HG-U133A	PIGQ PAOX HROB ACOT7 TRIM68 PLEKHA6 ITGA7 TG	4.54e-07	199	79	8	4140_UP
Disease	platelet crit	EOMES NCOA2 FLI1 PHKB ERG BCAS3 DCHS1 RCN2 UBXN2A PLEKHA6 HDAC7 SH3BP4	6.34e-06	952	77	12	EFO_0007985
Disease	Congenital Fiber Type Disproportion	MTMR14 MTM1 ITGA7	1.36e-05	18	77	3	C0546264
Disease	Centronuclear myopathy	MTMR14 MTM1	4.02e-05	4	77	2	cv:C0175709
Disease	Extra-osseous Ewing's sarcoma	FLI1 ERG	4.02e-05	4	77	2	C0279980
Disease	Ewings sarcoma	FLI1 ERG	1.86e-04	8	77	2	C0553580
Disease	treatment-resistant hypertension	POLR1A ERG BCAS3 SLC6A15	1.94e-04	109	77	4	EFO_1002006
Disease	neonatal systemic lupus erythematosus	ERG SLC6A15	2.39e-04	9	77	2	EFO_0004537
Disease	optic cup area measurement	BCAS3 SLC6A15 KPNB1	4.29e-04	56	77	3	EFO_0006940
Disease	Autosomal Dominant Myotubular Myopathy	MTMR14 MTM1	5.15e-04	13	77	2	C3661489
Disease	Centronuclear myopathy	MTMR14 MTM1	5.15e-04	13	77	2	C0175709
Disease	X-linked centronuclear myopathy	MTMR14 MTM1	5.15e-04	13	77	2	C0410203
Disease	Congenital Structural Myopathy	MTMR14 MTM1	5.15e-04	13	77	2	C0752282
Disease	Myopathy, Centronuclear, 1	MTMR14 MTM1	5.15e-04	13	77	2	C4551952
Disease	Pneumoconiosis	CA3 IL27RA	5.99e-04	14	77	2	C0032273
Disease	Bagassosis	CA3 IL27RA	5.99e-04	14	77	2	C0004681
Disease	Myopathy, Centronuclear, Autosomal Dominant	MTMR14 MTM1	5.99e-04	14	77	2	C1834558
Disease	Tubular Aggregate Myopathy	MTMR14 MTM1	5.99e-04	14	77	2	C0410207
Disease	Autosomal Recessive Centronuclear Myopathy	MTMR14 MTM1	6.90e-04	15	77	2	C3645536
Disease	multiple sclerosis	EOMES NCOA2 FLI1 ERG HLA-F KPNB1 TG	9.21e-04	594	77	7	MONDO_0005301
Disease	kidney volume	BCAS3 RAPGEF1	1.00e-03	18	77	2	EFO_0600044
Disease	lymphocyte count	EOMES NCOA2 FLI1 KIF27 BCAS3 ZNF638 UBXN2A PLEKHA6 HDAC7 IL27RA NMU	1.42e-03	1464	77	11	EFO_0004587
Disease	CCL11 measurement	BCAS3 SLC6A15	1.64e-03	23	77	2	EFO_0005188
Disease	retinitis pigmentosa (implicated_via_orthology)	USH2A CNGB1	2.26e-03	27	77	2	DOID:10584 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
WRNGDIVQPVLNPEP	ACOT7	206	O00154
RQQVQPLGKQRPAPW	CCDC137	26	Q6PK04
VSNWRPPQPINNRVV	CA3	241	P07451
VANPPQRWLVTPVQQ	EOMES	511	O95936
RQQRWQLSTLPEPPA	LINC00588	101	Q9Y4M8
VPQQDWLSQPPARVT	ERG	51	P11308
RPWVPQVPIQFHQQR	FAM187A	266	A6NFU0
ELQWLLQREQLSPPQ	DNHD1	3701	Q96M86
LVRTPQWNELQPPFN	BCAS3	656	Q9H6U6
RAWRQALPQLETPPN	CAMSAP3	86	Q9P1Y5
RLDPQELLPWVVPNN	RCN2	246	Q14257
GLPQPLILRWEQSPQ	HLA-F	286	P30511
LILRWEQSPQPTIPI	HLA-F	291	P30511
TLSWPQPEQPNGIIL	EPHB1	451	P54762
NDNRPTIPQPWELRV	DCHS1	2271	Q96JQ0
LPPQWQNILDTLRRP	PAK6	36	Q9NQU5
PVPRITWLLNGQPIQ	MYLK	541	Q15746
PVIWPNPVIWQNPVI	MAGED1	341	Q9Y5V3
NPVIWQNPVIWPNPI	MAGED1	346	Q9Y5V3
RPAPQVLATQPPLWQ	MAGEL2	501	Q9UJ55
IWQPLPAQEAQRQAP	MAGEL2	626	Q9UJ55
PLQPSWQAPPAVLQA	MAGEL2	681	Q9UJ55
ILPQGLQPEQQLQLW	NMU	41	P48645
WNRPQPSEDRLPSQQ	MTMR14	491	Q8NCE2
PVPTIQWLQNGRPAE	HMCN2	1746	Q8NDA2
NQWAPLNPIRNPIER	JAG2	1126	Q9Y219
WRNVQQREVPQGPSP	C9orf131	706	Q5VYM1
SALNWRKNPVPELQP	EFHC2	696	Q5JST6
LRTQPNPQKLWEDIP	KIF27	1286	Q86VH2
PRIPQAQPGEEWLQV	NRP2	476	O60462
VLPWEQPQQTVPRSP	ODAM	151	A1E959
GQPLWPPVFVNLETQ	IL27RA	111	Q6UWB1
WEVCPQRSPVQALQP	HROB	266	Q8N3J3
WANQNRAPVLSIDPP	EDC3	431	Q96F86
RNLPSFWQLPPQDQR	NR0B2	71	Q15466
PDRPQPSLAAVQWLQ	NR0B2	136	Q15466
LPIQPSRGVRQWQPD	NDUFS2	26	O75306
DPTLPQPQRLQWDLP	CPT1C	506	Q8TCG5
KNVPEWNPVPRTRQE	BTAF1	71	O14981
QNENPAVRPQPWVPS	GFRA3	371	O60609
LGLQRQSPWASPEQP	CROCC2	1301	H7BZ55
HKINPLPPQQEWINQ	FLI1	46	Q01543
LPPQQEWINQPVRVN	FLI1	51	Q01543
EPVPQQAWPNFLPLV	IGFLR1	151	Q9H665
IPVNQWPELIPQLVA	KPNB1	121	Q14974
WPELIPQLVANVTNP	KPNB1	126	Q14974
DNWPPSQNAIDPLRQ	IFIT2	186	P09913
AQARQADPQPQAWPP	KANK2	306	Q63ZY3
NPRENTWRPLTQVPE	KLHDC7B	326	Q96G42
NIPQTVENRLPQWLP	KRCC1	76	Q9NPI7
QLQPRPQSWLLVGAP	ITGA7	61	Q13683
PLQQHPQVLLWEQQR	HDAC7	441	Q8WUI4
SQRQNQVGVVPWSPP	DHX9	321	Q08211
QTQTPQQVEPIQIWP	PHKB	516	Q93100
QQVEPIQIWPQQELV	PHKB	521	Q93100
LLSLWAPQVQQPRPR	PAOX	496	Q6QHF9
EVNVNWLPPLLNQIA	GALNTL6	236	Q49A17
QLQEAWQQRTPSPVP	RSAD1	426	Q9HA92
QARGPQEILVNWDPP	USH2A	4541	O75445
QSFQQPLPWDQCPLV	SLC6A15	171	Q9H2J7
LTYPQPVTPWNVQEL	POLR1A	466	O95602
PQWQPKPRQEQPQSQ	SUPT20HL1	736	Q3ZLR7
QPPIRSPENTDWQRV	TEX14	976	Q8IWB6
RQAPNPAPVALQLWG	SH3BP4	511	Q9P0V3
PFWTLLQSNVPVLQP	FNBP4	691	Q8N3X1
IRNEQPVLVLAQWLP	NBEAL2	446	Q6ZNJ1
VQRVRPPQQPQVEGW	PIGQ	671	Q9BRB3
TWQTGLSQPVPRQPN	SATL1	416	Q86VE3
FWNVSTQPQQLPRPQ	SPATA31E1	406	Q6ZUB1
KVQWPPAEQLQVLLP	IQANK1	536	A8MXQ7
WLEQNLERVLPQPPK	CNGB1	161	Q14028
NQTAPWPESILPIDQ	NCOA2	1031	Q15596
NQLQQWVNLRRGVPP	PLEKHA6	316	Q9Y2H5
PRNLRPNWQLANVVE	TRIM68	66	Q6AZZ1
WNPRIKQQQPNPVEQ	MTM1	541	Q13496
DQIPQQTAWNLSPLP	RAPGEF1	401	Q13905
CPPRLDVQTIQPVLW	RYR3	1486	Q15413
WQQQPLVLPAPERLA	TBX22	381	Q9Y458
QQPQSPQRLLAVILW	SUSD4	21	Q5VX71
PLNNLEPITNIQIWL	UBXN2A	166	P68543
WNPQLLEVPPQTQFD	ACP6	76	Q9NPH0
QENPRAAWLPIANPI	SEMA5B	406	Q9P283
QQFPAWRAIRPIPIQ	ZNF229	171	Q9UJW7
KLLQPWLETQPPVEQ	TRIM66	381	O15016
SRRWKPPAVNQQFPQ	TTLL4	376	Q14679
TCIEPPQPRQDVLNW	PPP6R3	171	Q5H9R7
PQPRACQRPQLWQTI	TG	1276	P01266
QLRQQYPDWNPEILP	ZNF638	456	Q14966
QQPPQTRWVAPRNRN	YTHDF1	321	Q9BYJ9