Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	serine hydrolase activity	KLK15 OVCH2 CELA2A ST14 LPA TLL1 GZMA TMPRSS3 KLK8 NCEH1 HABP2 KLK5 PLG	5.40e-10	212	121	13	GO:0017171
GeneOntologyMolecularFunction	serine-type endopeptidase activity	KLK15 OVCH2 CELA2A ST14 LPA TLL1 GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	1.84e-09	190	121	12	GO:0004252
GeneOntologyMolecularFunction	serine-type peptidase activity	KLK15 OVCH2 CELA2A ST14 LPA TLL1 GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	4.87e-09	207	121	12	GO:0008236
GeneOntologyMolecularFunction	endopeptidase activity	KLK15 OVCH2 CELA2A ST14 USP20 LPA TLL1 GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	2.13e-06	430	121	13	GO:0004175
GeneOntologyMolecularFunction	benzodiazepine receptor binding	RIMBP3 RIMBP3C RIMBP3B	2.15e-06	5	121	3	GO:0030156
GeneOntologyMolecularFunction	peptidase activity	KLK15 OVCH2 CELA2A ST14 USP20 AGA LPA TLL1 GZMA TMPRSS3 KLK8 HABP2 USP35 KLK5 PLG	9.92e-06	654	121	15	GO:0008233
GeneOntologyMolecularFunction	histone reader activity	UIMC1 HDGFL2 TP53BP1	5.10e-04	26	121	3	GO:0140566
GeneOntologyMolecularFunction	ubiquitin-modified histone reader activity	UIMC1 TP53BP1	7.50e-04	7	121	2	GO:0061649
GeneOntologyMolecularFunction	laminin binding	GPC1 LYPD3 AGRN	1.13e-03	34	121	3	GO:0043236
GeneOntologyBiologicalProcess	cell morphogenesis	TRIM46 CDH26 RIPOR2 SYT3 DISC1 MINK1 BCL11A RREB1 PRPF40A ST14 PTN CCDC88C FRY BCL11B FARP1 TET1 KLK8 KIAA1755 AGRN GOLGA2 CUX1	7.45e-06	1194	123	21	GO:0000902
MousePheno	ectopic manchette	SPAG4 RIMBP3 RIMBP3C RIMBP3B	6.59e-06	19	93	4	MP:0009377
MousePheno	abnormal coat/ hair morphology	KLK15 AARS1 FRAS1 TBC1D30 DUSP7 EXOSC1 ST14 RCC2 VAC14 TRANK1 MAPK15 RACK1 PER2 AGA TET1 CHFR CUX1	4.17e-05	854	93	17	MP:0000367
MousePheno	abnormal mammary gland connective tissue morphology	LPA PLG	4.38e-05	2	93	2	MP:0009507
MousePheno	ectropion	LPA PLG	4.38e-05	2	93	2	MP:0006164
MousePheno	esophageal ulcer	LPA PLG	4.38e-05	2	93	2	MP:0004547
MousePheno	duodenal ulcer	LPA PLG	4.38e-05	2	93	2	MP:0003273
MousePheno	perianal ulcer	LPA PLG	4.38e-05	2	93	2	MP:0005035
MousePheno	absent cornea epithelium	LPA PLG	1.31e-04	3	93	2	MP:0020856
MousePheno	abnormal sperm nucleus morphology	SPAG4 RIMBP3 RIMBP3C RIMBP3B GOLGA2	1.31e-04	74	93	5	MP:0009232
MousePheno	detached acrosome	SPAG4 RIMBP3 RIMBP3C RIMBP3B	2.03e-04	44	93	4	MP:0009231
MousePheno	abnormal manchette morphology	SPAG4 RIMBP3 RIMBP3C RIMBP3B	2.22e-04	45	93	4	MP:0009376
MousePheno	increased circulating fibrinogen level	LPA PLG	2.60e-04	4	93	2	MP:0012331
MousePheno	proctitis	LPA PLG	2.60e-04	4	93	2	MP:0003305
Domain	TRYPSIN_SER	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	7.34e-11	106	119	11	PS00135
Domain	TRYPSIN_HIS	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	8.13e-11	107	119	11	PS00134
Domain	Peptidase_S1A	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	1.48e-10	113	119	11	IPR001314
Domain	TRYPSIN_DOM	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	1.79e-10	115	119	11	PS50240
Domain	Tryp_SPc	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	2.16e-10	117	119	11	SM00020
Domain	Trypsin_dom	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	3.11e-10	121	119	11	IPR001254
Domain	Trypsin	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	3.11e-10	121	119	11	PF00089
Domain	Peptidase_S1_PA	KLK15 OVCH2 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	3.72e-10	123	119	11	IPR009003
Domain	TRYPSIN_HIS	KLK15 CELA2A ST14 LPA GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	1.08e-09	103	119	10	IPR018114
Domain	TRYPSIN_SER	CELA2A ST14 GZMA TMPRSS3 KLK8 HABP2 KLK5 PLG	1.07e-07	90	119	8	IPR033116
Domain	Kringle_CS	LPA HABP2 PLG	1.61e-04	17	119	3	IPR018056
Domain	KRINGLE_1	LPA HABP2 PLG	1.61e-04	17	119	3	PS00021
Domain	KR	LPA HABP2 PLG	1.61e-04	17	119	3	SM00130
Domain	Kringle	LPA HABP2 PLG	1.61e-04	17	119	3	IPR000001
Domain	KRINGLE_2	LPA HABP2 PLG	1.61e-04	17	119	3	PS50070
Domain	Kringle	LPA HABP2 PLG	1.61e-04	17	119	3	PF00051
Domain	Pecanex_C	PCNX3 PCNX1	2.40e-04	4	119	2	PF05041
Domain	Pecanex	PCNX3 PCNX1	2.40e-04	4	119	2	IPR007735
Domain	CUB	OVCH2 ST14 TLL1 LRP3	2.66e-04	49	119	4	PF00431
Domain	CUB	OVCH2 ST14 TLL1 LRP3	2.88e-04	50	119	4	SM00042
Domain	CUB	OVCH2 ST14 TLL1 LRP3	3.61e-04	53	119	4	PS01180
Domain	CUB_dom	OVCH2 ST14 TLL1 LRP3	4.77e-04	57	119	4	IPR000859
Domain	Kringle-like	LPA HABP2 PLG	1.09e-03	32	119	3	IPR013806
Domain	FN3	TRIM46 RIMBP3 RIMBP3C EGFLAM RIMBP3B IL4R	1.74e-03	199	119	6	PS50853
Domain	LDLR_class-A_CS	ST14 TMPRSS3 LRP3	2.10e-03	40	119	3	IPR023415
Domain	Laminin_G_1	EGFLAM AGRN	2.13e-03	11	119	2	PF00054
Domain	FN3_dom	TRIM46 RIMBP3 RIMBP3C EGFLAM RIMBP3B IL4R	2.22e-03	209	119	6	IPR003961
Domain	SH3_2	RIMBP3 SASH3 RIMBP3C RIMBP3B	2.23e-03	86	119	4	PF07653
Domain	SH3_2	RIMBP3 SASH3 RIMBP3C RIMBP3B	2.23e-03	86	119	4	IPR011511
Domain	DUF4599	SPATA31A6 SPATA31C1	2.55e-03	12	119	2	PF15371
Domain	DUF4599	SPATA31A6 SPATA31C1	2.55e-03	12	119	2	IPR027970
Domain	SAM_2	PPFIBP2 DGKD SASH3	2.58e-03	43	119	3	PF07647
Domain	Ldl_recept_a	ST14 TMPRSS3 LRP3	2.94e-03	45	119	3	PF00057
Domain	FA	FARP1 EPB41L1	3.00e-03	13	119	2	PF08736
Domain	FERM-adjacent	FARP1 EPB41L1	3.00e-03	13	119	2	IPR014847
Domain	FA	FARP1 EPB41L1	3.00e-03	13	119	2	SM01195
Domain	-	ST14 TMPRSS3 LRP3	3.14e-03	46	119	3	4.10.400.10
Domain	LDLRA_1	ST14 TMPRSS3 LRP3	3.54e-03	48	119	3	PS01209
Domain	LDrepeatLR_classA_rpt	ST14 TMPRSS3 LRP3	3.75e-03	49	119	3	IPR002172
Domain	LDLa	ST14 TMPRSS3 LRP3	3.75e-03	49	119	3	SM00192
Domain	LDLRA_2	ST14 TMPRSS3 LRP3	3.75e-03	49	119	3	PS50068
Domain	EGF	FRAS1 GPR179 TLL1 HABP2 EGFLAM AGRN	3.97e-03	235	119	6	SM00181
Domain	-	ST14 TLL1 LRP3	4.44e-03	52	119	3	2.60.120.290
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	FRAS1 PCNX3 IRS1 ICE1 ATG2A ST14 CCDC88C VAC14 PNPLA6 PER2 SEC16A NAV2 LRP3 PCNX1 TNKS1BP1 RGL2 AGRN IL4R AHNAK2	1.66e-08	1105	125	19	35748872
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 RIPOR2 DIDO1 TRANK1 PER2 SEC16A EPB41L1	1.04e-07	104	125	7	9205841
Pubmed	RIM-BP3 is a manchette-associated protein essential for spermiogenesis.	RIMBP3 RIMBP3C RIMBP3B	1.81e-07	4	125	3	19091768
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	TRIM46 SYT3 MINK1 DIDO1 BCL11A CCDC88C FRY BCL11B RACK1 FARP1 SEC16A AGRN GOLGA2 CUX1 EPB41L1 TP53BP1	3.93e-07	963	125	16	28671696
Pubmed	Structure and evolution of RIM-BP genes: identification of a novel family member.	RIMBP3 RIMBP3C RIMBP3B	4.51e-07	5	125	3	17855024
Pubmed	CCL2/MCP-1 signaling drives extracellular matrix turnover by diverse macrophage subsets.	LPA PLG IL4R	8.99e-07	6	125	3	33543002
Pubmed	Regulation of cell surface protease matriptase by HAI2 is essential for placental development, neural tube closure and embryonic survival in mice.	KLK15 ST14 GZMA KLK8	9.08e-07	21	125	4	19592578
Pubmed	N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.	UIMC1 AARS1 DIDO1 ICE1 GPRIN1 PRPF40A RCC2 RACK1 SEC16A TNKS1BP1 BOD1L1 PRR14L HDGFL2 TP53BP1 AHNAK2	1.42e-06	934	125	15	33916271
Pubmed	DNA damage response in microcephaly development of MCPH1 mouse model.	BCL11B CUX1 TP53BP1	2.50e-06	8	125	3	23683352
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	AARS1 EXPH5 MINK1 IRS1 ARFGEF3 CCDC88C TET1 SEC16A NAV2 TNKS1BP1 BOD1L1 RGL2 EPB41L1 AHNAK2	2.83e-06	861	125	14	36931259
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DIDO1 ICE1 ATG2A RCC2 TUBGCP6 TRANK1 PLCH2 TET1 NAV2 PCNX1 TNKS1BP1	3.54e-06	529	125	11	14621295
Pubmed	The Specification of Cortical Subcerebral Projection Neurons Depends on the Direct Repression of TBR1 by CTIP1/BCL11a.	BCL11A BCL11B CUX1	3.75e-06	9	125	3	25972180
Pubmed	DISC1-dependent switch from progenitor proliferation to migration in the developing cortex.	DISC1 BCL11B CUX1	3.75e-06	9	125	3	21471969
Pubmed	Transsynaptic Binding of Orphan Receptor GPR179 to Dystroglycan-Pikachurin Complex Is Essential for the Synaptic Organization of Photoreceptors.	GPC1 GPR179 EGFLAM	3.75e-06	9	125	3	30282023
Pubmed	Neural-specific deletion of the focal adhesion adaptor protein paxillin slows migration speed and delays cortical layer formation.	BCL11A BCL11B CUX1	3.75e-06	9	125	3	28935710
Pubmed	Spatiotemporal Gradient of Cortical Neuron Death Contributes to Microcephaly in Knock-In Mouse Model of Ligase 4 Syndrome.	BCL11B CUX1 TP53BP1	3.75e-06	9	125	3	31541646
Pubmed	Suppression of DNA Double-Strand Break Formation by DNA Polymerase β in Active DNA Demethylation Is Required for Development of Hippocampal Pyramidal Neurons.	BCL11B CUX1 TP53BP1	7.32e-06	11	125	3	33087478
Pubmed	CRL5-dependent regulation of the small GTPases ARL4C and ARF6 controls hippocampal morphogenesis.	SOCS7 BCL11B CUX1	9.74e-06	12	125	3	32873638
Pubmed	Human tissue kallikreins: physiologic roles and applications in cancer.	KLK15 KLK8 KLK5	1.26e-05	13	125	3	15192120
Pubmed	Short-term inhibition of fibrinolytic system restores locomotor function after spinal cord injury in mice.	LPA PLG	1.28e-05	2	125	2	31690812
Pubmed	Blood-derived plasminogen drives brain inflammation and plaque deposition in a mouse model of Alzheimer's disease.	LPA PLG	1.28e-05	2	125	2	30254165
Pubmed	Plasminogen deficiency exacerbates skeletal muscle loss during mechanical unloading in developing mice.	LPA PLG	1.28e-05	2	125	2	38328826
Pubmed	Structure of the photoreceptor synaptic assembly of the extracellular matrix protein pikachurin with the orphan receptor GPR179.	GPR179 EGFLAM	1.28e-05	2	125	2	37490546
Pubmed	Reduced transplant arteriosclerosis in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	9819364
Pubmed	Persistent corneal haze after excimer laser photokeratectomy in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	10634603
Pubmed	Thrombomodulin functions as a plasminogen receptor to modulate angiogenesis.	LPA PLG	1.28e-05	2	125	2	23943648
Pubmed	In vivo plasminogen deficiency reduces fat accumulation.	LPA PLG	1.28e-05	2	125	2	12083480
Pubmed	Polymorphonuclear leukocyte phagocytic function increases in plasminogen knockout mice.	LPA PLG	1.28e-05	2	125	2	18420257
Pubmed	Plasminogen deficiency causes severe thrombosis but is compatible with development and reproduction.	LPA PLG	1.28e-05	2	125	2	7705657
Pubmed	Nucleocytoplasmic coagulation: an injury-induced aggregation event that disulfide crosslinks proteins and facilitates their removal by plasmin.	LPA PLG	1.28e-05	2	125	2	23041318
Pubmed	Plasminogen alleles influence susceptibility to invasive aspergillosis.	LPA PLG	1.28e-05	2	125	2	18566672
Pubmed	A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis.	LPA PLG	1.28e-05	2	125	2	19752236
Pubmed	COUP-TF (chicken ovalbumin upstream promoter transcription factor)-interacting protein 1 (CTIP1) is a sequence-specific DNA binding protein.	BCL11A BCL11B	1.28e-05	2	125	2	12196208
Pubmed	Plasminogen Tochigi: inactive plasmin resulting from replacement of alanine-600 by threonine in the active site.	LPA PLG	1.28e-05	2	125	2	6216475
Pubmed	The generation and characterization of mice expressing a plasmin-inactivating active site mutation.	LPA PLG	1.28e-05	2	125	2	20653841
Pubmed	Influence of plasminogen deficiency on the contribution of polymorphonuclear leucocytes to fibrin/ogenolysis: studies in plasminogen knock-out mice.	LPA PLG	1.28e-05	2	125	2	12428098
Pubmed	Tissue-type plasminogen activator is a neuroprotectant in the mouse hippocampus.	LPA PLG	1.28e-05	2	125	2	20440070
Pubmed	Plasminogen deficiency causes reduced corticospinal axonal plasticity and functional recovery after stroke in mice.	LPA PLG	1.28e-05	2	125	2	24732409
Pubmed	A central role for plasminogen in the inflammatory response to biomaterials.	LPA PLG	1.28e-05	2	125	2	15456492
Pubmed	Plasminogen promotes macrophage phagocytosis in mice.	LPA PLG	1.28e-05	2	125	2	24876560
Pubmed	Plasminogen is a joint-specific positive or negative determinant of arthritis pathogenesis in mice.	LPA PLG	1.28e-05	2	125	2	24574269
Pubmed	Spontaneous development of otitis media in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	16956791
Pubmed	Staphylococcus aureus manganese transport protein C (MntC) is an extracellular matrix- and plasminogen-binding protein.	LPA PLG	1.28e-05	2	125	2	25409527
Pubmed	The mouse plasminogen locus maps to the recombination breakpoints of the tLub2 and TtOrl partial t haplotypes but is not at the tw73 locus.	LPA PLG	1.28e-05	2	125	2	1543918
Pubmed	Restoration of thrombolytic potential in plasminogen-deficient mice by bolus administration of plasminogen.	LPA PLG	1.28e-05	2	125	2	8704243
Pubmed	Plasmin(ogen) promotes renal interstitial fibrosis by promoting epithelial-to-mesenchymal transition: role of plasmin-activated signals.	LPA PLG	1.28e-05	2	125	2	17267741
Pubmed	Plasmin promotes foam cell formation by increasing macrophage catabolism of aggregated low-density lipoprotein.	LPA PLG	1.28e-05	2	125	2	23702659
Pubmed	Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen on the surface of vascular endothelial and smooth muscle cells.	LPA PLG	1.28e-05	2	125	2	29990619
Pubmed	Reduction of experimental diabetic vascular leakage by delivery of angiostatin with a recombinant adeno-associated virus vector.	LPA PLG	1.28e-05	2	125	2	17293777
Pubmed	Structural basis for IL-4 receptor phosphopeptide recognition by the IRS-1 PTB domain.	IRS1 IL4R	1.28e-05	2	125	2	8599766
Pubmed	Plasminogen plays a crucial role in bone repair.	LPA PLG	1.28e-05	2	125	2	23456978
Pubmed	Disruption of the plasminogen gene in mice abolishes wound healing after myocardial infarction.	LPA PLG	1.28e-05	2	125	2	10854210
Pubmed	Gender affects skin wound healing in plasminogen deficient mice.	LPA PLG	1.28e-05	2	125	2	23527289
Pubmed	Dengue virus-induced autoantibodies bind to plasminogen and enhance its activation.	LPA PLG	1.28e-05	2	125	2	22079981
Pubmed	Plasminogen deficiency differentially affects recruitment of inflammatory cell populations in mice.	LPA PLG	1.28e-05	2	125	2	9490683
Pubmed	Kringle 5 of human plasminogen suppresses hepatocellular carcinoma growth both in grafted and xenografted mice by anti-angiogenic activity.	LPA PLG	1.28e-05	2	125	2	16481742
Pubmed	Apolipoprotein(a) inhibits the conversion of Glu-plasminogen to Lys-plasminogen: a novel mechanism for lipoprotein(a)-mediated inhibition of plasminogen activation.	LPA PLG	1.28e-05	2	125	2	18983515
Pubmed	Plasminogen Regulates Fracture Repair by Promoting the Functions of Periosteal Mesenchymal Progenitors.	LPA PLG	1.28e-05	2	125	2	34378815
Pubmed	Plasmin generation plays different roles in the formation and removal of arterial and venous thrombus in mice.	LPA PLG	1.28e-05	2	125	2	11848464
Pubmed	Effects of disruption of the plasminogen gene on thrombosis, growth, and health in mice.	LPA PLG	1.28e-05	2	125	2	7586361
Pubmed	Plasminogen/plasmin modulates bone metabolism by regulating the osteoblast and osteoclast function.	LPA PLG	1.28e-05	2	125	2	21239499
Pubmed	Plasminogen-independent initiation of the pro-urokinase activation cascade in vivo. Activation of pro-urokinase by glandular kallikrein (mGK-6) in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	10642175
Pubmed	Plasminogen mRNA induction in the mouse brain after kainate excitation: codistribution with plasminogen activator inhibitor-2 (PAI-2) mRNA.	LPA PLG	1.28e-05	2	125	2	12225871
Pubmed	Fibrinogen deficiency reduces vascular accumulation of apolipoprotein(a) and development of atherosclerosis in apolipoprotein(a) transgenic mice.	LPA PLG	1.28e-05	2	125	2	9770530
Pubmed	Plasminogen activation is required for the development of radiation-induced dermatitis.	LPA PLG	1.28e-05	2	125	2	30323258
Pubmed	Plasminogen deficiency suppresses pancreatic ductal adenocarcinoma disease progression.	LPA PLG	1.28e-05	2	125	2	37971174
Pubmed	The plasminogen activation system enhances brain and heart invasion in murine relapsing fever borreliosis.	LPA PLG	1.28e-05	2	125	2	9884337
Pubmed	Colonic Lesions, Cytokine Profiles, and Gut Microbiota in Plasminogen-Deficient Mice.	LPA PLG	1.28e-05	2	125	2	26473342
Pubmed	Nonfibrinolytic functions of plasminogen.	LPA PLG	1.28e-05	2	125	2	10816371
Pubmed	Plasminogen is a critical regulator of cutaneous wound healing.	LPA PLG	1.28e-05	2	125	2	26791370
Pubmed	Selection of mutant µplasmin for amyloid-β cleavage in vivo.	LPA PLG	1.28e-05	2	125	2	32694536
Pubmed	Angiostatin: a novel angiogenesis inhibitor that mediates the suppression of metastases by a Lewis lung carcinoma.	LPA PLG	1.28e-05	2	125	2	7525077
Pubmed	Cutting edge: Ly9 (CD229), a SLAM family receptor, negatively regulates the development of thymic innate memory-like CD8+ T and invariant NKT cells.	LY9 IL4R	1.28e-05	2	125	2	23225888
Pubmed	The BCL11 gene family: involvement of BCL11A in lymphoid malignancies.	BCL11A BCL11B	1.28e-05	2	125	2	11719382
Pubmed	Contrasting roles of plasminogen deficiency in different rheumatoid arthritis models.	LPA PLG	1.28e-05	2	125	2	16052596
Pubmed	Functional corpora lutea are formed in matrix metalloproteinase inhibitor-treated plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	17122079
Pubmed	Role of plasminogen in propagation of scrapie.	LPA PLG	1.28e-05	2	125	2	16103174
Pubmed	CTIP1 and CTIP2 are differentially expressed during mouse embryogenesis.	BCL11A BCL11B	1.28e-05	2	125	2	15465497
Pubmed	Differential expression of oxidized/native lipoprotein(a) and plasminogen in human carotid and cerebral artery plaques.	LPA PLG	1.28e-05	2	125	2	21300353
Pubmed	Beta-amyloid (Abeta) causes detachment of N1E-115 neuroblastoma cells by acting as a scaffold for cell-associated plasminogen activation.	LPA PLG	1.28e-05	2	125	2	15737740
Pubmed	Selective behaviors altered in plasminogen-deficient mice are reconstituted with intracerebroventricular injection of plasminogen.	LPA PLG	1.28e-05	2	125	2	11306011
Pubmed	Localization of regulatory elements mediating constitutive and cytokine-stimulated plasminogen gene expression.	LPA PLG	1.28e-05	2	125	2	12149246
Pubmed	Plasminogen deficiency attenuates postnatal erythropoiesis in male C57BL/6 mice through decreased activity of the LH-testosterone axis.	LPA PLG	1.28e-05	2	125	2	22056679
Pubmed	Protective effects of plasmin(ogen) in a mouse model of Staphylococcus aureus-induced arthritis.	LPA PLG	1.28e-05	2	125	2	18311818
Pubmed	Localization of plasminogen in mouse hippocampus, cerebral cortex, and hypothalamus.	LPA PLG	1.28e-05	2	125	2	21190118
Pubmed	The lack of binding of VEK-30, an internal peptide from the group A streptococcal M-like protein, PAM, to murine plasminogen is due to two amino acid replacements in the plasminogen kringle-2 domain.	LPA PLG	1.28e-05	2	125	2	18039665
Pubmed	Reduced metastasis of Polyoma virus middle T antigen-induced mammary cancer in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	9671388
Pubmed	A physiological function for apolipoprotein(a): a natural regulator of the inflammatory response.	LPA PLG	1.28e-05	2	125	2	18997104
Pubmed	Growth and behavioral development in plasminogen gene-targeted mice.	LPA PLG	1.28e-05	2	125	2	10885855
Pubmed	Cellular density regulation of plasminogen gene expression in mouse hepatocytes.	LPA PLG	1.28e-05	2	125	2	12559391
Pubmed	Physiologic variations in blood plasminogen levels affect outcomes after acute cerebral thromboembolism in mice: a pathophysiologic role for microvascular thrombosis.	LPA PLG	1.28e-05	2	125	2	27319402
Pubmed	Plasminogen is a critical host pathogenicity factor for group A streptococcal infection.	LPA PLG	1.28e-05	2	125	2	15333838
Pubmed	Apo(a) promotes thrombosis in a vascular injury model by a mechanism independent of plasminogen.	LPA PLG	1.28e-05	2	125	2	16150044
Pubmed	Plasminogen has a broad extrahepatic distribution.	LPA PLG	1.28e-05	2	125	2	11916082
Pubmed	Unaltered prion protein cleavage in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	16543819
Pubmed	Essential role of DNA-PKcs and plasminogen for the development of doxorubicin-induced glomerular injury in mice.	LPA PLG	1.28e-05	2	125	2	34423816
Pubmed	Delayed invasion of the kidney and brain by Borrelia crocidurae in plasminogen-deficient mice.	LPA PLG	1.28e-05	2	125	2	11500461
Pubmed	Growth of human squamous cell carcinoma xenografts in mice is inhibited by local angiostatin gene therapy.	LPA PLG	1.28e-05	2	125	2	12167431
Pubmed	Impaired wound healing in mice with a disrupted plasminogen gene.	LPA PLG	1.28e-05	2	125	2	8612226
Pubmed	Role of plasminogen activation in neuronal organization and survival.	LPA PLG	1.28e-05	2	125	2	19683575
Cytoband	22q11.21	RTL10 RIMBP3 RIMBP3C RIMBP3B	2.50e-04	111	125	4	22q11.21
GeneFamily	Kallikreins	KLK15 KLK8 KLK5	2.75e-05	16	68	3	616
Coexpression	LIAO_METASTASIS	SPAG4 SUSD4 PCNX3 BCL11A ST14 RCC2 SOCS7 ARFGEF3 RACK1 FARP1 CHFR AGRN	8.61e-06	540	122	12	M13809
Coexpression	CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP	TBC1D30 EXPH5 PPFIBP2 RTL10 ST14 ITPK1 ARFGEF3 PER2 LYPD3 TNKS1BP1 RGL2	9.52e-06	455	122	11	M17299
Coexpression	SANSOM_APC_TARGETS_REQUIRE_MYC	EXOSC1 BCL11A RCC2 USP20 BCL11B STOML1 NCEH1 BOD1L1	1.08e-05	225	122	8	M1757
Coexpression	NIKOLSKY_BREAST_CANCER_20Q11_AMPLICON	SPAG4 FAM83C CEP250 EPB41L1	1.28e-05	31	122	4	M10837
Coexpression	SANSOM_APC_TARGETS_REQUIRE_MYC	EXOSC1 BCL11A RCC2 USP20 BCL11B STOML1 NCEH1 BOD1L1	1.31e-05	231	122	8	MM737
Coexpression	JAEGER_METASTASIS_DN	EXPH5 DUSP7 BCL11A ST14 BCL11B PER2 KLK8 LYPD3	3.06e-05	260	122	8	M10702
Coexpression	AIZARANI_LIVER_C34_MHC_II_POS_B_CELLS	RIPOR2 DGKD BCL11A BOD1L1 PCDH9 IL4R	3.97e-05	134	122	6	M39133
Coexpression	GSE7831_1H_VS_4H_INFLUENZA_STIM_PDC_DN	GPATCH8 SH2D5 TET1 TMPRSS3 CHFR PCDH9 CUX1	4.19e-05	199	122	7	M6964
Coexpression	GSE11961_FOLLICULAR_BCELL_VS_GERMINAL_CENTER_BCELL_DAY40_UP	DGKD FRY KRBA1 AGA TET1 SIX5 CUX1	4.33e-05	200	122	7	M9313
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_10H_DN	TRIM46 AARS1 PTN TLL1 TET1 CHFR IL4R	4.33e-05	200	122	7	M9644
Coexpression	GSE7509_FCGRIIB_VS_TNFA_IL1B_IL6_PGE_STIM_DC_DN	UIMC1 DISC1 MINK1 KRBA1 PNPLA6 CEP250	8.61e-05	154	122	6	M6824
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SUSD4 RIPOR2 ATG2A CCDC88C BCL11B GZMA LYPD3 LY9	6.07e-08	189	124	8	5c92516c3745ccbd480b15bb2b9077ab1d9ee5a0
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 FARP1 TLL1 NAV2	7.14e-08	193	124	8	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SUSD4 CDH26 TBC1D30 SOCS7 ARFGEF3 FARP1 TLL1 NAV2	8.69e-08	198	124	8	5fc25b008a4d8d6bec83923a16f64dd9e1ff1f2d
ToppCell	Adult-Epithelial-club_cell-D122\|Adult / Lineage, Cell type, age group and donor	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 FARP1 TLL1	6.87e-07	178	124	7	35a2e3ba98b6f857dbb79cf8ddb4846ddcda6c17
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RIPOR2 RTL10 ICE1 BCL11B TRANK1 RACK1 PCNX1	7.98e-07	182	124	7	1aea96ee211f7b9caef7fd385233f51be6021a73
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 PTH1R FARP1 PLCH2 KIAA1755 PLG CUX1	7.98e-07	182	124	7	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RIPOR2 RTL10 ICE1 BCL11B TRANK1 RACK1 PCNX1	7.98e-07	182	124	7	b427e43ee523a3ea9eca3207f3d82042f10f022a
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 RTL10 ICE1 BCL11B TRANK1 RACK1 PCNX1	7.98e-07	182	124	7	c0f63cfc67d61c0877b7acb2946dfb35aae8a8f5
ToppCell	PBMC-Mild-Lymphocyte-T/NK-CD4+_T-CD4+_T_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 RTL10 ICE1 BCL11B TRANK1 RACK1 PCNX1	7.98e-07	182	124	7	4cb182ef39be2044a6ad7266f332d4177591e550
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	RIPOR2 RTL10 ICE1 BCL11B TRANK1 RACK1 PCNX1	8.28e-07	183	124	7	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	Adult-Epithelial-club_cell\|Adult / Lineage, Cell type, age group and donor	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 FARP1 TLL1	1.06e-06	190	124	7	756bff697d30aec56c0ebfca94295f084a15bf37
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 FARP1 TLL1	1.10e-06	191	124	7	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	Mild/Remission-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	SUSD4 RIPOR2 ICE1 RACK1 PCNX1 IL4R	1.15e-06	121	124	6	68940a552233d255b90ce5a081339c0d9d46ab02
ToppCell	LAM-LAM-LAM+\|LAM / Condition, Lineage and Cell class	PRUNE2 C10orf90 PTN HOXA10 KIAA1755 EGFLAM AHNAK2	1.22e-06	194	124	7	4ba73a9145ed44896e359f6df9c1f32bbe24a189
ToppCell	LAM-LAM\|LAM / Condition, Lineage and Cell class	PRUNE2 C10orf90 PTN HOXA10 KIAA1755 EGFLAM AHNAK2	1.22e-06	194	124	7	4c6561a64711c72c4ef4a3e67c41d2e8d31fba57
ToppCell	PCW_07-8.5-Epithelial\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.22e-06	194	124	7	f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.22e-06	194	124	7	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	PCW_10-12-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1 NCEH1	1.27e-06	195	124	7	d673f8844896d5c7b76a7bc7f6b88a039f1bc263
ToppCell	3'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 ATG2A CCDC88C BCL11B GZMA LYPD3 LY9	1.31e-06	196	124	7	ab6022041c33617bca3ed0c62f19673cd2750da9
ToppCell	Skin\|World / Skin and Kidney Cells in Lupus Nephritis Patients.	GPC1 EXPH5 BCL11A RACK1 KLK8 LYPD3 AHNAK2	1.45e-06	199	124	7	6be1340413ee868c610b6e3f58c65b493eb22bb5
ToppCell	Skin-Keratinocytes\|Skin / Skin and Kidney Cells in Lupus Nephritis Patients.	GPC1 EXPH5 DUSP7 BCL11A KLK8 LYPD3 AHNAK2	1.50e-06	200	124	7	59d72395199bc30df0e811fbc99149694e208860
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPC1 SUSD4 CDH26 BCL11A PTN PER2 PLCH2	1.50e-06	200	124	7	8827653738a931e4a4545e0c7d75be12bed40740
ToppCell	control-NK_CD56bright\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	FRAS1 RIPOR2 HOXA10 RACK1 PLCH2 GZMA	5.82e-06	160	124	6	f49c810072604c4dee51025073c9e088c00daf4a
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RIPOR2 DGKD BCL11A ATG2A SASH3 LY9	6.24e-06	162	124	6	59f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCell	5'-Adult-Appendix-Hematopoietic-B_cells-Naive_B\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 BCL11A SASH3 RIMBP3C LY9 IL4R	9.71e-06	175	124	6	d544f24ee33783ed4afb4d7ec079a4484118bb15
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 ICE1 TRANK1 RACK1 GZMA PCNX1	1.04e-05	177	124	6	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 ICE1 TRANK1 RACK1 GZMA PCNX1	1.04e-05	177	124	6	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	RIPOR2 ICE1 TRANK1 RACK1 GZMA PCNX1	1.04e-05	177	124	6	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	RIPOR2 ICE1 TRANK1 RACK1 GZMA PCNX1	1.04e-05	177	124	6	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	RIPOR2 ICE1 TRANK1 RACK1 GZMA PCNX1	1.04e-05	177	124	6	d5aeda113afaa2425874394610344570c9078478
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 NAV2	1.14e-05	180	124	6	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FRAS1 CDH26 SOCS7 ARFGEF3 FARP1 TLL1	1.21e-05	182	124	6	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 SUSD4 RIPOR2 EXPH5 KLRG2	1.21e-05	182	124	6	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	facs-Skin-Anagen-3m-Epithelial-nan\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 KLRG2 FAM83C SH2D5 BCL11B KLK8	1.37e-05	186	124	6	9a7932d0a208f3997216bd21a72913cc82b59fc9
ToppCell	Adult-Epithelial-club_cell-D231\|Adult / Lineage, Cell type, age group and donor	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 TLL1	1.41e-05	187	124	6	ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-interneuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PRUNE2 EXPH5 GPRIN1 SOCS7 ARFGEF3 PLCH2	1.41e-05	187	124	6	1b2fdbfb1ce3f19795dfc4b1da5a94f4b057ec41
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 RIPOR2 EXPH5 KLRG2 EPB41L1	1.41e-05	187	124	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 SUSD4 EXPH5 ARFGEF3 FRY TLL1	1.50e-05	189	124	6	7659c7bbd58ee959a159294fb8d17317bbcc5681
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 SUSD4 EXPH5 ST14 ARFGEF3 FRY	1.55e-05	190	124	6	c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.55e-05	190	124	6	ba61f04fd38efae01f721ba616252d1372ff1002
ToppCell	COVID-19-kidney-NK\|kidney / Disease (COVID-19 only), tissue and cell type	RIPOR2 DGKD CCDC88C BCL11B SASH3 GZMA	1.55e-05	190	124	6	e3ca3c9fb9e27670a5dd128dd6564ff98a57159e
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.55e-05	190	124	6	07ea0578ca0561077557203ae660530f53fc4067
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.55e-05	190	124	6	5a37568000dfc33fcbb59b578c1963fb7cf872ec
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-T_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.55e-05	190	124	6	5b4b3eed7aa798bb7e3c5e968c8dc4144e377a5f
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 SUSD4 EXPH5 ARFGEF3 FRY TLL1	1.59e-05	191	124	6	60ff989fe99d243a3d52955223680cdd1f1917a4
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.59e-05	191	124	6	96a7179a845d3daa046ed71fa45c51255f130a7f
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.64e-05	192	124	6	b498618505bb1b7ff9574d06875dd272c11bac39
ToppCell	PCW_07-8.5-Epithelial-Epithelial_neuroendo-epi_NE_progenitor_(7)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	FRAS1 SUSD4 EXPH5 ARFGEF3 FRY TMPRSS3	1.64e-05	192	124	6	b99f8236ef4ccdc75c02abea381cae6453205f6f
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.69e-05	193	124	6	12f1333f11e6c262954ad7912d8fd2962ab06d25
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 PTH1R FARP1 CUX1 EPB41L1	1.69e-05	193	124	6	3866667dd221612589ae50f5c52f73a183a49ce6
ToppCell	PCW_05-06-Epithelial-Epithelial_airway\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.69e-05	193	124	6	af6ec2c2ba92aef3e41531c3c7215b3300437bd9
ToppCell	PCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.74e-05	194	124	6	c5ef4ff73b4e51530656002e3a2fb7264cdf533d
ToppCell	PCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating1_(8)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 TMPRSS3 C3orf80	1.74e-05	194	124	6	20f81f457ab0a404600effe8beb91fe73d1cfc10
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway-epi_proximal_progenitor2_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.74e-05	194	124	6	6b286992d4bb56013c0ea5a7601d3476d806175a
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_secretory_(0)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.74e-05	194	124	6	b19e16a76d7342ff9a665d19c9151652916f17d4
ToppCell	PCW_05-06-Epithelial\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	SUSD4 EXPH5 ST14 ARFGEF3 FRY TLL1	1.74e-05	194	124	6	47a1369c22fcbfe00b08376eb610a61c355548db
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.74e-05	194	124	6	633fe72cc8a489abde12428e326478409ca03263
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Lymphocytic_T/NK-T_Cell-\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.74e-05	194	124	6	87a86df0b542f287b0b20f4a4b1a37002271671d
ToppCell	facs-Tongue\|facs / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPFIBP2 KLRG2 RCC2 BCL11B PLCH2 LYPD3	1.79e-05	195	124	6	77128895db9221a64a171082d468ebcd6380c936
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Lymphoid\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	RIPOR2 CCDC88C BCL11B GZMA KLK8 LY9	1.90e-05	197	124	6	80ffafa9473f4ee7a3a792d11b5541e1c984c9f0
ToppCell	COVID-19-kidney-T-cells-1\|kidney / Disease (COVID-19 only), tissue and cell type	RIPOR2 CCDC88C BCL11B SASH3 GZMA LY9	1.90e-05	197	124	6	9bb7faf4ef63cca4d06c60e6c05a9616fdb6b98e
ToppCell	cellseq-Epithelial-Epithelial_Airway-Basal/Suprabasal-Suprabasal\|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	GPC1 SUSD4 ST14 PTN LYPD3 AHNAK2	1.95e-05	198	124	6	6e047de63ef59dcb47e4fc06b173b2a02fdcf4c9
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 FARP1	1.95e-05	198	124	6	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Club\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FRAS1 SUSD4 CDH26 SOCS7 ARFGEF3 FARP1	1.95e-05	198	124	6	1408e02e053ad3406229bfe8189da03be6366e81
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	FRAS1 EXPH5 PTH1R PTN FARP1 NAV2	1.95e-05	198	124	6	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	Tracheal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	SUSD4 ST14 ARFGEF3 FARP1 TMPRSS3 KLK5	2.01e-05	199	124	6	ef1a0c278c23614fd6a3218a9733abe6ecd6f686
ToppCell	5'-GW_trimst-2-LymphNode-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RIPOR2 BCL11B SASH3 GZMA LYPD3 LY9	2.01e-05	199	124	6	b01328a80db5bb088c44564cea0f6729b1a9805b
ToppCell	Biopsy_Control_(H.)-Epithelial-KRT5-/KRT17+\|Biopsy_Control_(H.) / Sample group, Lineage and Cell type	GPC1 WFDC3 LRP3 HABP2 AGRN AHNAK2	2.01e-05	199	124	6	3b1f56c8b40bb36922a31d2d440a8c468a8aa3f1
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_basal-Suprabasal\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	GPC1 SUSD4 CDH26 BCL11A PTN PER2	2.01e-05	199	124	6	f5c3561744e2a0e7716657cb521acb1d8f054b41
ToppCell	Tracheal-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPC1 SUSD4 CDH26 ST14 PTN LYPD3	2.07e-05	200	124	6	5f0f67958c9635db53e61f8370a92da6ea3e80fe
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW26-Neuronal-GABAergic_neurons\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	RIPOR2 JPH4 BCL11A SOCS7 BCL11B CUX1	2.07e-05	200	124	6	bad32a95b759fad509401b07bc96a56687c2a592
ToppCell	Bronchial-10x5prime-Epithelial-Epi_airway_basal-Suprabasal\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	GPC1 SUSD4 CDH26 PTN PLCH2 LYPD3	2.07e-05	200	124	6	ce969c958a31145bbfe315a9a865d7900ecc9549
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 GPRIN1 ZNF252P-AS1 BCL11B TET1	4.70e-05	141	124	5	31e0984f09983e83a814424f74c871c1c5a3a789
ToppCell	356C-Epithelial_cells-Epithelial-E_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	FRAS1 GPRIN1 ZNF252P-AS1 BCL11B TET1	4.70e-05	141	124	5	d7d3c3932651d90fa4f3c4e3df16f4b677faaf9f
ToppCell	Mild/Remission-B_naive-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIPOR2 ICE1 RACK1 PCNX1 IL4R	5.02e-05	143	124	5	bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell	3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor\|bone_marrow / Manually curated celltypes from each tissue	BCL11A PTH1R HOXA10 EFCC1 PCDH9	6.11e-05	149	124	5	078e1e5765e476ba85c23fb8f6892b6698cbcbdb
ToppCell	facs-BAT-Fat-24m-Lymphocytic-NK_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPC1 PCNX3 CCDC88C GZMA HDGFL2	7.36e-05	155	124	5	550e7e7e52829244ead829e5be010bfdc71e2ba5
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIPOR2 ICE1 RACK1 PCNX1 IL4R	7.36e-05	155	124	5	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	E18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-NK-NK_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	RIPOR2 ITPK1 SASH3 GZMA LY9	8.55e-05	160	124	5	4a0ae0a83a10dbfc13591f4d2228ba8bcd2c2275
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPAG4 SPCS1 APOBR TXNDC15 LY9	9.07e-05	162	124	5	ee6f05620f4f4ebbebd5b098afc7c20876e3d21f
ToppCell	kidney_cells-Adult_normal_reference-Immune-Lymphocytic_B-Plasma_Cell-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SPAG4 SPCS1 APOBR TXNDC15 LY9	9.07e-05	162	124	5	9e72d468fcdd0d27b517a9e36efb35d4617a88f9
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	ATG2A USP20 SLC6A11 PLG TRMT61B	9.33e-05	163	124	5	e4077e587895c85bc806be05ff5d451088e39468
ToppCell	droplet-Liver-LIVER-NPC-1m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 BCL11A B3GNT8 FRY SASH3	9.33e-05	163	124	5	66ecd544d7b52e61880b125bf39d1f406af6900a
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-SPN_Neuron_STR\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11A SH2D5 CCDC88C BCL11B TRANK1	9.89e-05	165	124	5	1b7dfa173e83aa8c46a3153a3261866c065c3b73
ToppCell	PBMC-Severe-Lymphocyte-B-B_cell-B_naive-B_naive-1\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	RIPOR2 BCL11A RACK1 PCDH9 IL4R	9.89e-05	165	124	5	fead3f2032f8fa5f7f0159a4434989b3d65debbb
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-medium_spiny_neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCL11A SH2D5 CCDC88C BCL11B TRANK1	9.89e-05	165	124	5	b4f7d33af7d053ec07b01bd67d861600a9c4822e
ToppCell	facs-Heart-RA-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 BCL11A ST14 SASH3 LY9	1.02e-04	166	124	5	fc2cf67311c86fda75b35fcd4768b6f6f14c59d0
ToppCell	facs-GAT-Fat-3m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 BCL11B SASH3 KLK8 LY9	1.02e-04	166	124	5	3695407e4638f3c18fbff63daba52baa9256c429
ToppCell	facs-Heart-RA-18m-Lymphocytic-B_cell\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 BCL11A ST14 SASH3 LY9	1.02e-04	166	124	5	33a6876d06e26176135a73a77c19e634ec53f7ce
ToppCell	Basal_cells-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	GPC1 FRAS1 IRS1 LYPD3 AHNAK2	1.02e-04	166	124	5	aea2ae12e4746149ebc6da063ef694381c098f80
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RIPOR2 ICE1 TRANK1 RACK1 PCNX1	1.05e-04	167	124	5	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 JPH4 PPFIBP2 PTN AHNAK2	1.05e-04	167	124	5	7abc785e688a384672d7fb5a62d32538fe7e5a51
ToppCell	PND10-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FRAS1 JPH4 PPFIBP2 PTN AHNAK2	1.05e-04	167	124	5	d50311b1f66f143bae4c4cf50e2e9b13c85d6920
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 CDH26 BCL11A PER2 PLCH2	1.08e-04	168	124	5	6521bead9789d626b86cbd08692c621c5a5aef33
ToppCell	facs-Lung-EPCAM-3m-Lymphocytic-B_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 DGKD BCL11A SASH3 LY9	1.08e-04	168	124	5	784ce773521e5d74570f45120e56d112bc76ff49
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 FRAS1 KLRG2 FARP1 EPB41L1	1.08e-04	168	124	5	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	facs-Aorta-Heart-24m-Mesenchymal-fibroblast_of_cardiac_tissue\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAM83C PTN TMPRSS3 LYPD3 HABP2	1.11e-04	169	124	5	daed9083ee05c220365200328c2c50047fe21efd
ToppCell	facs-Lung-24m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ITPK1 BCL11B SASH3 GZMA TRMT61B	1.11e-04	169	124	5	dbf9b1d52b29bf4b60bd23012cc1ea82d344747f
ToppCell	Fetal_29-31_weeks-Epithelial-basal_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	FRAS1 CDH26 BCL11A PER2 PLCH2	1.11e-04	169	124	5	c3ee781735a9288ce1822b230d39bb91c1415589
ToppCell	facs-MAT-Fat-24m-Lymphocytic-CD8-positive,_alpha-beta_T_cell\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RIPOR2 ARID5A BCL11B SASH3 KLK8	1.11e-04	169	124	5	3a18b4ad826e6ab9cbfd1d51a23a1b67c9a08596
Drug	diisopropylfluorophosphate	KLK15 SPCS1 CELA2A ST14 PNPLA6 GZMA KLK8 HABP2 KLK5 PLG	6.85e-06	321	118	10	CID000005936
Drug	retinoic acid; Down 200; 1uM; MCF7; HT_HG-U133A_EA	GPC1 CCDC88C VAC14 BCL11B LYPD3 LRP3 PCDH9 IL4R	7.05e-06	191	118	8	991_DN
Drug	Acyclovir [59277-89-3]; Down 200; 17.8uM; HL60; HG-U133A	DISC1 DIDO1 BCL11A ATG2A CCDC88C VAC14 AGRN CUX1	8.52e-06	196	118	8	2044_DN
Drug	Mometasone furoate [83919-23-7]; Down 200; 7.6uM; HL60; HG-U133A	DIDO1 BCL11A ATG2A APOBR PCNX1 PRR14L TSR3 TP53BP1	8.84e-06	197	118	8	1746_DN
Drug	ICI182,780; Up 200; 1uM; PC3; HT_HG-U133A	TBC1D30 MINK1 USP20 VAC14 FARP1 LRP3 COG4 GOLGA2	9.52e-06	199	118	8	7539_UP
Drug	EACA	KLK15 ST14 RIT2 LPA KLK8 KLK5 PLG	1.40e-05	151	118	7	CID000000564
Drug	Anisomycin [22862-76-6]; Down 200; 15uM; HL60; HT_HG-U133A	AARS1 TBC1D30 MINK1 DUSP7 BCL11A APOBR SASH3	4.81e-05	183	118	7	1304_DN
Drug	Terconazole [67915-31-5]; Up 200; 7.6uM; MCF7; HT_HG-U133A	DISC1 MINK1 BCL11A HOXA10 PCNX1 PCDH9 AHNAK2	6.95e-05	194	118	7	2844_UP
Drug	Strophanthidin [66-28-4]; Down 200; 9.8uM; PC3; HT_HG-U133A	DUSP7 BCL11A HOXA10 RACK1 CEP250 TSR3 AHNAK2	6.95e-05	194	118	7	5826_DN
Drug	Azlocillin sodium salt [37091-65-9]; Down 200; 8.2uM; HL60; HT_HG-U133A	SPAG4 TBC1D30 EXPH5 PPFIBP2 CEP250 AGRN PCDH9	7.18e-05	195	118	7	2727_DN
Drug	Testosterone propionate [57-85-2]; Down 200; 11.6uM; MCF7; HT_HG-U133A	TBC1D30 DISC1 ITPK1 LYPD3 IL4R COG4 GOLGA2	7.18e-05	195	118	7	2649_DN
Drug	chlorazanil	KLK15 KLK8 KLK5	7.23e-05	16	118	3	CID000010374
Drug	Pantothenic acid calcium salt monohydrate [63409-48-3]; Up 200; 8uM; HL60; HT_HG-U133A	PPFIBP2 DISC1 ST14 SASH3 CEP250 LRP3 TSR3	7.41e-05	196	118	7	1311_UP
Drug	Muramic acid, N-acetyl [10597-89-4]; Up 200; 13.6uM; HL60; HT_HG-U133A	GPC1 TBC1D30 PPFIBP2 HOXA10 PCNX1 KLK5 AGRN	7.41e-05	196	118	7	1326_UP
Drug	Suxibuzone [27470-51-5]; Down 200; 9.2uM; MCF7; HT_HG-U133A	GPC1 DISC1 DUSP7 WDR25 ITPK1 FARP1 CEP250	7.41e-05	196	118	7	6065_DN
Drug	Esculetin [305-01-1]; Up 200; 22.4uM; MCF7; HT_HG-U133A	WDR25 PTH1R ITPK1 PTN STOML1 PCNX1 AHNAK2	7.65e-05	197	118	7	7459_UP
Drug	Ethamivan [304-84-7]; Up 200; 18uM; PC3; HT_HG-U133A	DUSP7 BCL11A USP20 BCL11B STOML1 LRP3 IL4R	7.65e-05	197	118	7	7260_UP
Drug	Quipazine dimaleate salt [4774-24-7]; Down 200; 9uM; PC3; HT_HG-U133A	EXPH5 DISC1 PTN LYPD3 LRP3 IL4R GOLGA2	7.65e-05	197	118	7	5887_DN
Drug	PHA-00816795 [212631-79-3]; Up 200; 10uM; PC3; HT_HG-U133A	GPC1 DISC1 MINK1 USP20 VAC14 PCNX1 CUX1	7.90e-05	198	118	7	7076_UP
Drug	Decamethonium bromide [541-22-0]; Up 200; 9.6uM; MCF7; HT_HG-U133A	TBC1D30 PPFIBP2 ATG2A BCL11B FARP1 PCNX1 GOLGA2	7.90e-05	198	118	7	7353_UP
Drug	Propranolol hydrochloride [318-98-9]; Up 200; 13.6uM; HL60; HT_HG-U133A	GPC1 MINK1 PTH1R SOCS7 HOXA10 TRANK1 CEP250	7.90e-05	198	118	7	3059_UP
Drug	Ergocryptine-alpha [511-09-1]; Down 200; 7uM; MCF7; HT_HG-U133A	GPC1 DUSP7 DIDO1 ATG2A ST14 CCDC88C BCL11B	7.90e-05	198	118	7	3434_DN
Drug	Triamterene [396-01-0]; Up 200; 15.8uM; PC3; HT_HG-U133A	GPC1 RTL10 TRANK1 STOML1 LYPD3 LRP3 PCDH9	7.90e-05	198	118	7	7307_UP
Drug	fluphenazine dihydrochloride; Down 200; 10uM; HL60; HT_HG-U133A	MINK1 RTL10 WDR25 ST14 PER2 CEP250 KLK5	7.90e-05	198	118	7	6196_DN
Drug	Aminocaproic Acid	LPA PLG	7.96e-05	3	118	2	DB00513
Drug	Mecamylamine hydrochloride [826-39-1]; Down 200; 19.6uM; PC3; HT_HG-U133A	PTN CCDC88C FARP1 PCNX1 KLK5 IL4R COG4	8.15e-05	199	118	7	7263_DN
Drug	Butacaine [149-16-6]; Down 200; 13uM; PC3; HT_HG-U133A	TBC1D30 RTL10 BCL11A PTN LRP3 KLK5 GOLGA2	8.15e-05	199	118	7	5748_DN
Drug	Glafenine hydrochloride [65513-72-6]; Up 200; 9.8uM; MCF7; HT_HG-U133A	EXPH5 ST14 USP20 PTN PER2 IL4R GOLGA2	8.15e-05	199	118	7	7418_UP
Drug	Buspirone hydrochloride [33386-08-2]; Down 200; 9.4uM; HL60; HT_HG-U133A	CCDC88C VAC14 PNPLA6 CEP250 LY9 TSR3 CUX1	8.41e-05	200	118	7	1282_DN
Drug	camostate	KLK15 ST14 KLK8 KLK5 PLG	9.55e-05	88	118	5	CID000002536
Disease	copine-1 measurement	SPAG4 CEP250 EPB41L1	3.97e-05	17	117	3	EFO_0008102
Disease	plasma plasminogen measurement	LPA PLG	1.55e-04	5	117	2	EFO_0006309
Disease	chronic kidney disease, APOL1 risk genotype carrier status	LPA PLG	1.55e-04	5	117	2	EFO_0003884, EFO_0009324
Disease	kallikrein-8 measurement	KLK8 KLK5	2.31e-04	6	117	2	EFO_0020516
Disease	angiostatin measurement	LPA PLG	2.31e-04	6	117	2	EFO_0008024
Disease	glypican-1 measurement	GPC1 HABP2	3.23e-04	7	117	2	EFO_0801649
Disease	lipoprotein A measurement, apolipoprotein A 1 measurement	LPA PLG	3.23e-04	7	117	2	EFO_0004614, EFO_0006925
Disease	cerebellar ataxia (implicated_via_orthology)	AARS1 PNPLA6	4.30e-04	8	117	2	DOID:0050753 (implicated_via_orthology)
Disease	response to selective serotonin reuptake inhibitor, body mass index	GPC1 PLCH2	4.30e-04	8	117	2	EFO_0004340, EFO_0005658
Disease	lipoprotein-associated phospholipase A(2) measurement	LPA PLG TP53BP1	5.39e-04	40	117	3	EFO_0004746
Disease	post-operative acute kidney injury	CDH26 RCC2	5.51e-04	9	117	2	EFO_0009955
Disease	free cholesterol to total lipids in very small VLDL percentage	LPA PLG TP53BP1	6.68e-04	43	117	3	EFO_0022290
Disease	airway wall thickness measurement	C10orf90 BCL11B	1.00e-03	12	117	2	EFO_0006898
Disease	polyunsaturated fatty acids to monounsaturated fatty acids ratio	LPA PLG TP53BP1	1.10e-03	51	117	3	EFO_0022302
Disease	monokine induced by gamma interferon measurement	BCL11A LPA PLG	1.17e-03	52	117	3	EFO_0008236
Disease	Malignant neoplasm of breast	GPC1 KLK15 SYT3 BCL11A TXNDC15 PER2 FARP1 TLL1 BOD1L1 MAGEC2 CUX1 TP53BP1	1.17e-03	1074	117	12	C0006142
Disease	triglycerides in HDL measurement	LPA PLG TP53BP1	1.23e-03	53	117	3	EFO_0022317
Disease	triglycerides in medium HDL measurement	LPA PLG TP53BP1	1.30e-03	54	117	3	EFO_0022321
Disease	triglycerides in LDL measurement	LPA PLG TP53BP1	1.45e-03	56	117	3	EFO_0022320
Disease	triglycerides to total lipids in medium HDL percentage	LPA PLG TP53BP1	1.45e-03	56	117	3	EFO_0022333
Disease	cholesteryl esters to total lipids in medium HDL percentage	LPA PLG TP53BP1	1.45e-03	56	117	3	EFO_0022251
Disease	angina pectoris	PCNX3 LPA STOML1 PLG	1.57e-03	125	117	4	EFO_0003913
Disease	triglycerides to total lipids in small LDL percentage	LPA PLG TP53BP1	1.68e-03	59	117	3	EFO_0022337
Disease	adverse effect, response to xenobiotic stimulus	ST14 RIT2 NAV2	1.68e-03	59	117	3	EFO_0009658, GO_0009410
Disease	triglycerides to total lipids in large HDL percentage	LPA PLG TP53BP1	1.76e-03	60	117	3	EFO_0022330
Disease	cholesterol to total lipids in medium HDL percentage	LPA PLG TP53BP1	1.76e-03	60	117	3	EFO_0022237
Disease	triglycerides in small VLDL measurement	LPA PLG TP53BP1	1.85e-03	61	117	3	EFO_0022145
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	LPA PLG TP53BP1	1.85e-03	61	117	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	triglycerides in small HDL measurement	LPA PLG TP53BP1	1.94e-03	62	117	3	EFO_0022158
Disease	phospholipids in large VLDL measurement	LPA PLG TP53BP1	1.94e-03	62	117	3	EFO_0022169
Disease	triglycerides in medium LDL measurement	LPA PLG TP53BP1	1.94e-03	62	117	3	EFO_0022322
Disease	triglycerides to total lipids in very large HDL percentage	LPA PLG TP53BP1	1.94e-03	62	117	3	EFO_0022339
Disease	triglycerides to total lipids in medium VLDL percentage	LPA PLG TP53BP1	2.03e-03	63	117	3	EFO_0022335
Disease	cholesterol to total lipids in medium VLDL percentage	LPA PLG TP53BP1	2.03e-03	63	117	3	EFO_0022239
Disease	free cholesterol to total lipids in medium LDL percentage	LPA PLG TP53BP1	2.03e-03	63	117	3	EFO_0022283
Disease	phospholipids in chylomicrons and extremely large VLDL measurement	LPA AGRN TP53BP1	2.03e-03	63	117	3	EFO_0022292
Disease	triglycerides in small LDL measurement	LPA PLG TP53BP1	2.22e-03	65	117	3	EFO_0022323
Disease	squamous cell carcinoma	RCC2 SEC16A EPB41L1	2.42e-03	67	117	3	EFO_0000707
Disease	cholesterol to total lipids in very small VLDL percentage	LPA PLG TP53BP1	2.42e-03	67	117	3	EFO_0022245
Disease	triglycerides to phosphoglycerides ratio	LPA PLG TP53BP1	2.52e-03	68	117	3	EFO_0022327
Disease	free cholesterol in large VLDL measurement	LPA PLG TP53BP1	2.52e-03	68	117	3	EFO_0022265
Disease	triglycerides to total lipids in very small VLDL percentage	LPA PLG TP53BP1	2.63e-03	69	117	3	EFO_0022341
Disease	Endometrial Carcinoma	HOXA10 CHFR CUX1	2.97e-03	72	117	3	C0476089
Disease	triglycerides to total lipids in small HDL percentage	LPA PLG TP53BP1	2.97e-03	72	117	3	EFO_0022336
Disease	C-reactive protein measurement	RREB1 PTH1R USP20 RIT2 TRANK1 LPA RP1L1 SEC16A TNKS1BP1 IL4R CUX1 TP53BP1	3.05e-03	1206	117	12	EFO_0004458
Disease	Deep Vein Thrombosis	LPA PLG	3.12e-03	21	117	2	C0149871
Disease	Venous Thrombosis	LPA PLG	3.12e-03	21	117	2	C0042487
Disease	free cholesterol to total lipids in large LDL percentage	LPA PLG TP53BP1	3.21e-03	74	117	3	EFO_0022280
Disease	free cholesterol to total lipids in small VLDL percentage	LPA PLG TP53BP1	3.33e-03	75	117	3	EFO_0022287
Disease	monounsaturated fatty acids; 16:1, 18:1 measurement	LPA PLG TP53BP1	3.72e-03	78	117	3	EFO_0022187

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSGCSSDSEGDEGLP	ERFL	326	A0A1W2PQ73
DELGGSPGSTSAATC	ARID5A	116	Q03989
DCGSGTGVLRSEDPL	EGFLAM	676	Q63HQ2
PSEGVGGGRCSEISA	COG4	16	Q9H9E3
SGRAAPSSEGDSCDG	CUX1	1326	P39880
LRGGRDSCNGDSGSP	GZMA	201	P12544
PGAATRGSGVGECGD	AGRN	1536	O00468
STASGTCGGKPAERG	RTL10	66	Q7L3V2
DGVISSCNGDSGGPL	CELA2A	206	P08217
SLGSAGERGEAEGCP	DISC1	216	Q9NRI5
GCGGRTLGTSEEEAE	EFCC1	471	Q9HA90
GGPAGSLGSCSEEKE	ATG2A	1331	Q2TAZ0
RERPERCSSSSGGGS	RCC2	36	Q9P258
SPDGSLCASGGKDGQ	RACK1	201	P63244
GSEGECPSSGAGSQA	RIMBP3B	1261	A6NNM3
GSEGECPSSGAGSQA	RIMBP3C	1261	A6NJZ7
VPTSGDCGLGTREGT	PTN	56	P21246
DCSRDEGGSPEGASP	PNPLA6	1331	Q8IY17
ESGGIEDSPDRGACS	EPB41L1	671	Q9H4G0
DSSCSSGPTGDGVQG	KRBA1	136	A5PL33
GCIENTGTGDRFGPE	FRAS1	1881	Q86XX4
AGGLVGERTCSASPG	ITPK1	346	Q13572
GEDTGTCQGLPDSES	MAGEC2	121	Q9UBF1
PGSSECSGSLGSGIA	GPR179	1446	Q6PRD1
SGSGSGDGCLDDLCS	GPC1	486	P35052
RGESPSREAGTSSGC	KIAA1755	286	Q5JYT7
CGGSSGTSREKGPEG	MAPK15	346	Q8TD08
RDGSPLLGGCSDSSG	JPH4	526	Q96JJ6
SSRGPDAGCLTEELG	JPH4	576	Q96JJ6
TVNGRGCSPGESASG	BCL11A	601	Q9H165
SLSEGDGVPGQGCSE	CCDC88C	1961	Q9P219
SCGLGSEFSTDKGGP	GPATCH8	246	Q9UKJ3
GTGRGSEGDCSPEDK	GPATCH8	1071	Q9UKJ3
SLGSGSLGCDASPSG	PER2	1076	O15055
NIEDSDTGGGTSCTG	PCNX1	2046	Q96RV3
DDSDCSGGGGLTSLS	PCNX3	1836	Q9H6A9
GAESCEGDSGGPLVC	KLK15	201	Q9H2R5
PDGSQESCSDSGLGD	PCDH9	1056	Q9HC56
DPGRICISGDSAGGN	NCEH1	181	Q6PIU2
SDGGSLGDQGCFSEP	LRP3	381	O75074
ECTGSGRAIPFTGSG	EXPH5	1446	Q8NEV8
SPSSGCGEGSISVGE	TUBGCP6	1331	Q96RT7
GERLCNLEEGSPGSG	EXOSC1	11	Q9Y3B2
AGRDSCQGDSGGPVV	KLK5	236	Q9Y337
PTLACGSGGGSQGDE	HOXA10	276	P31260
CSGSSGLGEAGEDLS	IRS1	136	P35568
PGTGGDSVCGETHRA	GOLGA2	786	Q08379
EGRDSEEGPRCGSSE	HDGFL2	621	Q7Z4V5
GADLSDGTCEPGLAS	PPFIBP2	26	Q8ND30
RDGVTGPGFTLSGSC	LYPD3	201	O95274
PGDGERRLSGSSLCS	PRPF40A	26	O75400
ITEDGEGPASCTGSE	BOD1L1	1796	Q8NFC6
QGDSGGPLTCEKDGT	HABP2	506	Q14520
SPAGRERSSSCGSGG	CHFR	196	Q96EP1
SPEKCGFGASSGEEG	IL4R	616	P24394
VEETSCGDTGRSGGE	ICE1	1016	Q9Y2F5
GCDAEGRASPAEGSA	KLRG2	196	A4D1S0
CSARPVSGDGTQGEG	BCL11B	186	Q9C0K0
GCSSGLDSLVPGDED	BCL6B	311	Q8N143
TFGEGAESPGGQSCR	FARP1	396	Q9Y4F1
PGGGDCSDTGVVSSS	FAM83C	366	Q9BQN1
ATGSAGLLGDPECEG	ARFGEF3	1046	Q5TH69
VCESRPELSGGGDSA	CEP250	1196	Q9BV73
GRGGGGRSDPSCASE	C3orf80	166	F5H4A9
RPGDADGTDCTSIGT	DIDO1	341	Q9BTC0
GLGGLRISSDCSDGE	DUSP7	206	Q16829
RGTDSCQGDSGGPLV	LPA	1981	P08519
FCTDPGASRGGTTGE	LY9	241	Q9HBG7
REQCDGSVGFGGSPD	AGA	66	P20933
EEGECGGAPSLSSLA	CDH26	786	Q8IXH8
DGDGSGSICGSTGDR	DGKD	576	Q16760
SSKGADTCQGDSGGP	KLK8	201	O60259
GGSRDGVITCQPGDS	FRY	2806	Q5TBA9
GAGEGASCSDGPRGS	GPRIN1	76	Q7Z2K8
GSLPSGDSTETGGCQ	B3GNT8	81	Q7Z7M8
PRDSGCFEGSESGRD	SASH3	346	O75995
GSEPGRCGLVDSTAG	PRR14L	86	Q5THK1
EGSRDTPGGRSDGDT	MINK1	846	Q8N4C8
SGEAGTGAPCGRISF	SYT3	291	Q9BQG1
EGTASGGPDGSCDSS	VAC14	361	Q08AM6
GGPDGSCDSSFSSGI	VAC14	366	Q08AM6
RSASCGSPLSGGAEE	RGL2	616	O15211
AGLTGRDGPTAGCTV	TRIM46	671	Q7Z4K8
CSGGAAIPSDGQTEG	PRUNE2	1141	Q8WUY3
DSTAVGLGRFCGSGP	TLL1	956	O43897
GSEGECPSSGAGSQA	RIMBP3	1261	Q9UFD9
AGPSSATCESGAGSE	SPATA31A6	836	Q5VVP1
EASCSPGSASGGSRE	RIT2	6	Q99578
TGFPDGGRDACQGDS	OVCH2	226	Q7RTZ1
RGPGGHSCLVESEGS	SH2D5	276	Q6ZV89
GSKAGEGPGSRDTSC	NAV2	436	Q8IVL1
DRTGAGGGAPCKSES	SIX5	256	Q8N196
LAGPSSDTCESGAGS	SPATA31C1	691	P0DKV0
GGTDSCQGDSGGPLV	PLG	751	P00747
CGAATVRGGASEPTG	SPAG4	91	Q9NPE6
EGSVGGESEGCRSFL	RIPOR2	586	Q9Y4F9
GPLEGTRCGEGLFSE	TET1	216	Q8NFU7
DLSTEGDSRGCGLGD	AHNAK2	5126	Q8IVF2
GDSRGCGLGDVPVSQ	AHNAK2	5131	Q8IVF2
SAGAEDSCGLDPAGS	APOBR	846	Q0VD83
TCGAGSPGTLEEGVA	PAK6-AS1	66	Q8N910
PRDGAGSPGLSEDCS	C10orf90	546	Q96M02
TGGVDSCQGDSGGPL	TMPRSS3	391	P57727
STGCGRTCLGDIEGG	WFDC3	151	Q8IUB2
GDAGGTPGETVRHCS	STK19	71	P49842
ELEDSSGDQGRCGPT	TRMT61B	101	Q9BVS5
SGPAGSLTSVEFCGG	AARS1	711	P49588
GSGCAPLEADSGASG	SEC16A	356	O15027
RPEGSQGGELSRCSS	SEC16A	2281	O15027
DPGVCSTAGLTEDSG	SPEM3	851	A0A1B0GUW6
GSGGSGESSVPCAMD	RP1L1	1206	Q8IWN7
GSCSGLDEEASGPER	PTH1R	566	Q03431
APAAEASGRGEDSGC	RREB1	836	Q92766
GCLSPERGGVGTGAD	STOML1	31	Q9UBI4
RGTPEGACSVGHEGS	PLCH2	1376	O75038
IPSGERTCGSEGSRS	USP35	746	Q9P2H5
GGVDSCQGDSGGPLS	ST14	796	Q9Y5Y6
GSGDTDTGPGESETC	SUSD4	416	Q5VX71
TGCLESGGSEEPGGI	TNKS1BP1	1206	Q9C0C2
EVTCDPDSGGSQGLR	TNKS1BP1	1321	Q9C0C2
SSEPSGVTCGAGGAE	TXNDC15	106	Q96J42
EEARESEAPGGGCSS	SLC6A11	16	P48066
MARGGDTGCTGPSET	SPCS1	1	Q9Y6A9
GDEDTEPGEACGGRT	TBC1D30	61	Q9Y2I9
EPGEACGGRTSRTAS	TBC1D30	66	Q9Y2I9
GCTATAGREGSSPEG	TBC1D30	776	Q9Y2I9
SDGCSTPSREEGGCS	TP53BP1	316	Q12888
CDSSSDRGEGDGQGR	USP20	286	Q9Y2K6
SCSEEELSSPGRGGG	SOCS7	131	O14512
PDTERSCGRSSTGGC	ZNF252P-AS1	41	Q0IIN9
CSPGGDLLVTGSADG	WDR25	481	Q64LD2
TLGAGAPDCSEVGEG	TRANK1	731	O15050
GDGPEGSGRACSTVE	UIMC1	591	Q96RL1
GPGAERGGASSSCCE	TSR3	271	Q9UJK0
RLPGESGSCEDGQSA	UNQ6190/PRO20217	91	Q6UXQ8