Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyCellularComponent	mismatch repair complex	PMS2P1 PMS2P3 PMS2	7.74e-05	11	166	3	GO:0032300
Domain	DUF1220	NBPF11 NBPF1 NBPF15 NBPF9 NBPF14	1.44e-08	11	151	5	PF06758
Domain	NBPF_dom	NBPF11 NBPF1 NBPF15 NBPF9 NBPF14	1.44e-08	11	151	5	IPR010630
Domain	NBPF	NBPF11 NBPF1 NBPF15 NBPF9 NBPF14	1.44e-08	11	151	5	PS51316
Domain	DUF1220	NBPF11 NBPF1 NBPF15 NBPF9	5.01e-07	9	151	4	SM01148
Domain	Chap_CCT_zeta	CCT6A CCT6B	6.49e-05	2	151	2	IPR012722
Domain	Znf_piccolo	PCLO BSN	6.49e-05	2	151	2	IPR008899
Domain	zf-piccolo	PCLO BSN	6.49e-05	2	151	2	PF05715
Domain	ARM-type_fold	DOCK2 IFT172 APOB HEATR1 ECPAS PPP4R3A ITPR2 AP4E1 IFRD1 AP2A2 UPF2	1.00e-04	339	151	11	IPR016024
Domain	C2	PCLO SYTL5 PLCL2 PLCB1 SYT5 PKN1 PLA2G4F	1.26e-04	137	151	7	SM00239
Domain	C2	PCLO SYTL5 PLCL2 PLCB1 SYT5 PKN1 PLA2G4F	1.57e-04	142	151	7	PS50004
Domain	-	PCLO SYTL5 PLCL2 PLCB1 SYT5 PKN1 PLA2G4F	2.03e-04	148	151	7	2.60.40.150
Domain	C2_dom	PCLO SYTL5 PLCL2 PLCB1 SYT5 PKN1 PLA2G4F	3.79e-04	164	151	7	IPR000008
Domain	HIN_200	IFI16 PYHIN1	3.85e-04	4	151	2	PS50834
Domain	HIN	IFI16 PYHIN1	3.85e-04	4	151	2	PF02760
Domain	HIN200/IF120x	IFI16 PYHIN1	3.85e-04	4	151	2	IPR004021
Domain	SMC	SMC1A SMC1B	6.39e-04	5	151	2	IPR024704
Domain	C2	PCLO SYTL5 PLCL2 PLCB1 SYT5 PLA2G4F	6.89e-04	131	151	6	PF00168
Domain	SMC_hinge	SMC1A SMC1B	9.53e-04	6	151	2	SM00968
Domain	SMC_hinge	SMC1A SMC1B	9.53e-04	6	151	2	PF06470
Domain	SMC_hinge	SMC1A SMC1B	9.53e-04	6	151	2	IPR010935
Domain	DH_1	RASGRF2 ARHGEF11 FGD1 DNMBP	1.69e-03	63	151	4	PS00741
Domain	Coatomer/calthrin_app_sub_C	AP4E1 AP2A2	1.76e-03	8	151	2	IPR009028
Domain	RecF/RecN/SMC_N	SMC1A SMC1B	1.76e-03	8	151	2	IPR003395
Domain	SMC_N	SMC1A SMC1B	1.76e-03	8	151	2	PF02463
Domain	RhoGEF	RASGRF2 ARHGEF11 FGD1 DNMBP	2.24e-03	68	151	4	SM00325
Domain	Chaprnin_Cpn60	CCT6A CCT6B	2.25e-03	9	151	2	IPR001844
Domain	Chaperonin_TCP-1_CS	CCT6A CCT6B	2.25e-03	9	151	2	IPR002194
Domain	RhoGEF	RASGRF2 ARHGEF11 FGD1 DNMBP	2.49e-03	70	151	4	PF00621
Domain	DH_2	RASGRF2 ARHGEF11 FGD1 DNMBP	2.49e-03	70	151	4	PS50010
Domain	-	RASGRF2 ARHGEF11 FGD1 DNMBP	2.62e-03	71	151	4	1.20.900.10
Domain	DH-domain	RASGRF2 ARHGEF11 FGD1 DNMBP	2.62e-03	71	151	4	IPR000219
Domain	TCP1_1	CCT6A CCT6B	2.80e-03	10	151	2	PS00750
Domain	TCP1_2	CCT6A CCT6B	2.80e-03	10	151	2	PS00751
Domain	TCP1_3	CCT6A CCT6B	2.80e-03	10	151	2	PS00995
Domain	Chaperone_TCP-1	CCT6A CCT6B	2.80e-03	10	151	2	IPR017998
Domain	PyrdxlP-dep_Trfase_major_sub2	PDXDC1 PSAT1 SPTLC2	3.04e-03	36	151	3	IPR015422
Domain	RWD	EIF2AK4 UBE2Q2	3.40e-03	11	151	2	SM00591
Domain	-	CCT6A CCT6B	3.40e-03	11	151	2	3.30.260.10
Domain	TCP-1-like_intermed	CCT6A CCT6B	3.40e-03	11	151	2	IPR027410
Domain	RWD	EIF2AK4 UBE2Q2	3.40e-03	11	151	2	PF05773
Domain	Laminin_G_1	LAMA1 SLIT2	3.40e-03	11	151	2	PF00054
Domain	LAM_G_DOMAIN	FAT3 LAMA1 SLIT2	3.55e-03	38	151	3	PS50025
Domain	GDS_CDC24_CS	ARHGEF11 FGD1 DNMBP	3.83e-03	39	151	3	IPR001331
Domain	RWD-domain	EIF2AK4 UBE2Q2	4.06e-03	12	151	2	IPR006575
Domain	Laminin_G_2	FAT3 LAMA1 SLIT2	4.11e-03	40	151	3	PF02210
Domain	PyrdxlP-dep_Trfase	PDXDC1 PSAT1 SPTLC2	4.41e-03	41	151	3	IPR015424
Domain	PyrdxlP-dep_Trfase_major_sub1	PDXDC1 PSAT1 SPTLC2	4.41e-03	41	151	3	IPR015421
Domain	Keratin_I	KRT18 KRT27 KRT25	5.38e-03	44	151	3	IPR002957
Domain	LamG	FAT3 LAMA1 SLIT2	5.38e-03	44	151	3	SM00282
Domain	IBR	RNF144A FBXO43	5.54e-03	14	151	2	PF01485
Domain	GROEL-like_equatorial	CCT6A CCT6B	5.54e-03	14	151	2	IPR027413
Domain	IBR	RNF144A FBXO43	5.54e-03	14	151	2	SM00647
Domain	-	CCT6A CCT6B	5.54e-03	14	151	2	1.10.560.10
Domain	Cys-rich_flank_reg_C	IGSF10 SLIT2 SLITRK5 GP1BA	6.13e-03	90	151	4	IPR000483
Domain	LRRCT	IGSF10 SLIT2 SLITRK5 GP1BA	6.13e-03	90	151	4	SM00082
Domain	Clathrin/coatomer_adapt-like_N	AP4E1 AP2A2	6.36e-03	15	151	2	IPR002553
Domain	EF-hand_like	PLCL2 PLCB1	6.36e-03	15	151	2	PF09279
Domain	PI-PLC-Y	PLCL2 PLCB1	6.36e-03	15	151	2	PF00387
Domain	PLCYc	PLCL2 PLCB1	6.36e-03	15	151	2	SM00149
Domain	GroEL-like_apical_dom	CCT6A CCT6B	6.36e-03	15	151	2	IPR027409
Domain	Cpn60/TCP-1	CCT6A CCT6B	6.36e-03	15	151	2	IPR002423
Domain	Adaptin_N	AP4E1 AP2A2	6.36e-03	15	151	2	PF01602
Domain	IBR_dom	RNF144A FBXO43	6.36e-03	15	151	2	IPR002867
Domain	Cpn60_TCP1	CCT6A CCT6B	6.36e-03	15	151	2	PF00118
Domain	-	CCT6A CCT6B	6.36e-03	15	151	2	3.50.7.10
Domain	PLipase_C_Pinositol-sp_Y	PLCL2 PLCB1	6.36e-03	15	151	2	IPR001711
Domain	PIPLC_Y_DOMAIN	PLCL2 PLCB1	6.36e-03	15	151	2	PS50008
Domain	PI-PLC_fam	PLCL2 PLCB1	6.36e-03	15	151	2	IPR001192
Domain	PLC_EF-hand-like	PLCL2 PLCB1	6.36e-03	15	151	2	IPR015359
Domain	ARM-like	DOCK2 HEATR1 ECPAS PPP4R3A AP4E1 IFRD1 AP2A2	6.46e-03	270	151	7	IPR011989
Domain	Znf_FYVE_PHD	PCLO SYTL5 PHF11 FGD1 BSN	6.89e-03	147	151	5	IPR011011
Domain	PINT	EIF3E COPS2	7.23e-03	16	151	2	SM00088
Domain	PH_dom-like	RASGRF2 MYO7A TBC1D2 ARHGEF11 PPP4R3A PLCL2 OSBPL9 PLCB1 FGD1	7.89e-03	426	151	9	IPR011993
Pubmed	A novel gene family NBPF: intricate structure generated by gene duplications during primate evolution.	NBPF8 NBPF12 NBPF11 NBPF1 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14	2.89e-16	21	166	9	16079250
Pubmed	Evolutionary history and genome organization of DUF1220 protein domains.	NBPF8 NBPF12 NBPF1 NBPF15 NBPF9 NBPF14	2.23e-12	10	166	6	22973535
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	PDXDC1 MAGED1 KRT18 RASGRF2 EIF1B SMC1A RPS9 EIF3E NELFB PARVB HEATR1 DBT ECPAS COPS2 ACTR2 PPP4R3A RASGRP1 LOXHD1 CDK2AP1 MTHFD1 PA2G4 CLK2 PIN1 CNOT1 CAPRIN1	2.53e-09	1284	166	25	17353931
Pubmed	Why do cellular proteins linked to K63-polyubiquitin chains not associate with proteasomes?	NBPF8 NBPF12 USP25 NBPF11 NBPF1 SLIT2 NBPF9 CEP83 NBPF10 NBPF14	1.03e-08	170	166	10	23314748
Pubmed	E3 ubiquitin ligase RNF123 targets lamin B1 and lamin-binding proteins.	MYO7A POLA1 PCLO RPS9 LAMA1 TBC1D2 NELFB CHD2 ECPAS ITPR2 IGSF10 NUDT12 LOXHD1 MTHFD1 FBXO43 CNOT1 GP1BA DOP1B	1.76e-08	736	166	18	29676528
Pubmed	FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.	RASGRF2 MYO7A VPS50 CHD2 ECPAS ARHGEF11 COPS2 PPP1R10 GTF2F2 LOXHD1 HP MTHFD1 EIF2AK4 CTNNA1 CNOT1	1.91e-08	497	166	15	36774506
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	BCL2L14 PSAT1 MAGED1 KRT18 SPTLC2 NT5C3A EIF3E HEATR1 ECPAS IFI16 COPS2 IFIT1 ACTR2 POLR3A ITPR2 NBAS CCT6A COMMD4 AP2A2 PA2G4 NFKB1 OS9 CTNNA1 CNOT1 CAPRIN1	2.43e-08	1440	166	25	30833792
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	KRT18 MYO5A SPTLC2 POLA1 SMC1A RPS9 EIF3E ADNP2 CLIC4 MCM4 CHD2 HEATR1 URB2 IFI16 POLR3A CCT6A AP2A2 UPF2 MTHFD1 PA2G4 PIN1 CCT6B MACF1 CAPRIN1	3.20e-08	1353	166	24	29467282
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	PSAT1 KRT18 POLA1 SMC1A RPS9 EIF3E MCM4 COPS2 ACTR2 PPP1R10 CCT6A UPF2 HPD PA2G4 MACF1	5.38e-08	538	166	15	28524877
Pubmed	Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.	KRT18 MYO5A DSG3 SMC1A RPS9 EIF3E HEATR1 ZFC3H1 ITGA4 DBT IFI16 SQOR ACTR2 ITPR2 PPP1R10 CCT6A GTF2F2 UPF2 MTHFD1 PA2G4 CTNNA1 CAPRIN1	1.60e-07	1257	166	22	36526897
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	MAGED1 MYO5A EIF3E WHAMM NBPF26 CHD2 HEATR1 URB2 ZFC3H1 ARHGEF11 SQOR TFAP2C GGCX PPP1R10 CCT6A GTF2F2 IFRD1 CDK2AP1 MTHFD1 PA2G4 CEP83 MACF1 OS9 DNMBP	2.07e-07	1497	166	24	31527615
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	PDXDC1 PSAT1 KRT18 POLA1 SMC1A RPS9 TBC1D2 EIF3E NELFB USP25 MCM4 ECPAS COPS2 ACTR2 PPP4R3A CCT6A GTF2F2 MTHFD1 PA2G4 MACF1 CTNNA1 DNMBP CNOT1	4.87e-07	1455	166	23	22863883
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	KRT18 MYO5A SMC1A RPS9 MCM4 HEATR1 URB2 ACTR2 ITPR2 SLIT2 PPP1R10 CCT6A MTHFD1 PA2G4 PIN1 MACF1 CTNNA1 CNOT1 PCNT	5.02e-07	1024	166	19	24711643
Pubmed	An Interaction Landscape of Ubiquitin Signaling.	PMS2 MYO5A CFAP36 VPS50 LAMA1 UBXN6 USP25 DBT COPS2 FCHO1 AP2A2 MACF1 PCNT	6.10e-07	481	166	13	28190767
Pubmed	Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.	P4HA2 MYO5A SMC1A EIF3E CLIC4 MCM4 COPS2 ACTR2 PPP1R10 AP2A2 SYNJ2 EHHADH CCT6B CNOT1 CAPRIN1	7.97e-07	665	166	15	30457570
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	DOCK2 SPTLC2 SMC1A RNF144A NELFB ZFC3H1 FCHO1 PPP4R3A AP2A2 DNAH17 SLITRK5 MACF1 CGNL1	8.03e-07	493	166	13	15368895
Pubmed	Defining the membrane proteome of NK cells.	DOCK2 MYO5A VPS50 RPS9 EIF3E MCM4 FIS1 HEATR1 ITGA4 ECPAS IFI16 ACTR2 POLR3A ITPR2 NBAS MTHFD1 PA2G4 CNOT1 CAPRIN1 PCNT	8.60e-07	1168	166	20	19946888
Pubmed	New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.	NBPF8 NBPF12 MYO7A IFT172 RPS9 MCM4 APOB NBPF11 NBPF1 NBPF15 NBPF9 NBPF10 NBPF14	1.25e-06	513	166	13	25798074
Pubmed	Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.	PSAT1 POLA1 SMC1A PCLO RPS9 EIF3E MCM4 APOB HEATR1 URB2 DBT ECPAS ACTR2 POLR3A CCT6A AP2A2 MTHFD1 PA2G4 PNPLA8 BSN CNOT1 CAPRIN1	1.30e-06	1425	166	22	30948266
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	TUT4 MAGED1 MYO5A POLA1 ZFC3H1 ACTR2 SLIT2 PPP1R10 UPF2 SYNJ2 MACF1 DNMBP CNOT1 TXLNG CAPRIN1	2.27e-06	724	166	15	36232890
Pubmed	A protein interaction landscape of breast cancer.	PMS2 MYO5A SPTLC2 CLIC4 ECPAS COPS2 SQOR ACTR2 PPP1R10 AP2A2 PA2G4 MACF1 OS9 CTNNA1	2.41e-06	634	166	14	34591612
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	PDXDC1 POLA1 IFT172 SMC1A RPS9 EIF3E NELFB MCM4 HEATR1 ECPAS PPP4R3A CCT6A MTHFD1 CNOT1	2.59e-06	638	166	14	33239621
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	PSAT1 TUT4 MYO5A RNF144A ROR2 FBXL17 CHD2 PARVB ECPAS NBPF1 BICD1 IFRD1 SYNJ2 CLK2 SGSM2 OSBPL9 MACF1 OS9 PKN1 EIF2AK4 CNOT1 PCNT	2.66e-06	1489	166	22	28611215
Pubmed	Tumor suppressor BAP1 nuclear import is governed by transportin-1.	PSAT1 MAGED1 KRT18 MYO5A SMC1A RPS9 EIF3E CLIC4 MCM4 ECPAS COPS2 ACTR2 CCT6A AP2A2 MTHFD1 PA2G4 MACF1 CNOT1 CAPRIN1	2.74e-06	1149	166	19	35446349
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	MAGED1 EIF3E CLIC4 MCM4 PPP1R10 CCT6A MTHFD1 MACF1 CNOT1 CAPRIN1	3.08e-06	315	166	10	26777405
Pubmed	Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.	MYO7A SMC1A RPS9 EIF3E MCM4 ACTR2 PPP4R3A POLR3A CCT6A GTF2F2 UPF2 PA2G4 MACF1 TXLNG CAPRIN1 PCNT	3.36e-06	847	166	16	35235311
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	MYO5A POLA1 EIF3E MCM4 CHD2 HEATR1 URB2 ECPAS ACTR2 MACF1 CTNNA1 CNOT1 CAPRIN1 PCNT	3.39e-06	653	166	14	22586326
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PMS2 MAGED1 MYO5A IFT172 SMC1A USP25 ADNP2 WHAMM CLIC4 PARVB ZFC3H1 BICD1 SGSM2 OLFM1 MACF1 CTNNA1 TXLNG CAPRIN1 DOP1B PCNT	3.65e-06	1285	166	20	35914814
Pubmed	A human MAP kinase interactome.	KRT18 CFAP36 ADNP2 ARHGEF11 PPP4R3A SYNJ2 PLCB1 MACF1 OS9 CTNNA1 CGNL1 TXLNG	4.23e-06	486	166	12	20936779
Pubmed	CHK2-BRCA1 tumor-suppressor axis restrains oncogenic Aurora-A kinase to ensure proper mitotic microtubule assembly.	KRT18 SMC1A RPS9 EIF3E MCM4 ECPAS CCT6A MTHFD1 PA2G4 CTNNA1 CNOT1 CAPRIN1	4.99e-06	494	166	12	26831064
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	PMS2 KRT18 RPS9 EIF3E HEATR1 SQOR ITPR2 CCT6A MTHFD1	5.15e-06	262	166	9	36880596
Pubmed	Proteomic analysis of integrin-associated complexes identifies RCC2 as a dual regulator of Rac1 and Arf6.	KRT18 RPS9 EIF3E MCM4 HEATR1 ITGA4 ECPAS ACTR2 CCT6A AP2A2 MTHFD1 PA2G4 MACF1 CNOT1	8.34e-06	707	166	14	19738201
Pubmed	Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.	PDXDC1 DOCK2 PCLO RPS9 EIF3E ECPAS ACTR2 NBAS CCT6A AP2A2 MTHFD1 MACF1 CTNNA1 ARHGAP18 CNOT1	8.35e-06	807	166	15	30575818
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	SMC1A RPS9 EIF3E MCM4 DBT ECPAS PPP1R10 CCT6A AP2A2 CDK2AP1 MTHFD1 PA2G4 CTNNA1 CNOT1 CAPRIN1	8.60e-06	809	166	15	32129710
Pubmed	A High-Density Human Mitochondrial Proximity Interaction Network.	PDXDC1 TUT4 CFAP36 NT5C3A PCLO FIS1 HEATR1 DBT IFIT1 ACTR2 POLR3A ITPR2 NBAS CCT6A UPF2 OSBPL9 PNPLA8 CAPRIN1 DDX4 SPRYD4 PCNT	9.97e-06	1496	166	21	32877691
Pubmed	VCP phosphorylation-dependent interaction partners prevent apoptosis in Helicobacter pylori-infected gastric epithelial cells.	PDXDC1 VPS50 RPS9 UBXN6 HEATR1 CCT6A AP2A2 CDK2AP1 CTNNA1	1.10e-05	288	166	9	23383273
Pubmed	Quantitative Lys-ϵ-Gly-Gly (diGly) proteomics coupled with inducible RNAi reveals ubiquitin-mediated proteolysis of DNA damage-inducible transcript 4 (DDIT4) by the E3 ligase HUWE1.	PSAT1 RPS9 EIF3E MCM4 DBT ACTR2 PPP4R3A PPP1R10 CCT6A MTHFD1	1.48e-05	377	166	10	25147182
Pubmed	The human cytoplasmic dynein interactome reveals novel activators of motility.	DBT ECPAS ARHGEF11 BICD1 AP4E1 CCT6A SYNJ2 PIN1 NFKB1 CCT6B CGNL1 DNMBP CNOT1 TXLNG PCNT	1.60e-05	853	166	15	28718761
Pubmed	Genomic organization of the human PMS2 gene family.	PMS2P1 PMS2P3 PMS2	1.71e-05	11	166	3	8586419
Pubmed	Dynamic Protein Interactions of the Polycomb Repressive Complex 2 during Differentiation of Pluripotent Cells.	MAGED1 SMC1A MCM4 CHD2 TFAP2C PPP1R10 CCT6A CLK2 NFKB1 CTNNA1 CNOT1	1.73e-05	469	166	11	27634302
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	PDXDC1 SPTLC2 SMC1A VPS50 NELFB MCM4 ECPAS COPS2 PPP4R3A PPP1R10 AP2A2 CNOT1	1.74e-05	560	166	12	35241646
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	MYO5A FAT3 RPS9 LAMA1 SLIT2 SYCP1 MACF1 CGNL1	1.80e-05	234	166	8	36243803
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	MYO5A SMC1A RPS9 EIF3E HEATR1 URB2 ZFC3H1 DBT UPF2 PA2G4 MACF1 HSF2 CNOT1 TXLNG	1.84e-05	759	166	14	35915203
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	P4HA2 MYO7A IFT172 SMC1A VPS50 EIF3E MCM4 HEATR1 COPS2 PPP4R3A SLIT2 PPP1R10 AP2A2 PA2G4 NFKB1 PLCL2 CTNNA1 CNOT1 TXLNG	1.95e-05	1321	166	19	27173435
Pubmed	Peptidylproline cis-trans-isomerase Pin1 interacts with human T-cell leukemia virus type 1 tax and modulates its activation of NF-kappaB.	PIN1 NFKB1	2.26e-05	2	166	2	19158244
Pubmed	Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.	PCLO BSN	2.26e-05	2	166	2	23403927
Pubmed	Role of Bassoon and Piccolo in Assembly and Molecular Organization of the Active Zone.	PCLO BSN	2.26e-05	2	166	2	26793095
Pubmed	Ins(1,4,5)P(3) regulates phospholipase Cbeta1 expression in cardiomyocytes.	ITPR2 PLCB1	2.26e-05	2	166	2	18692062
Pubmed	Piccolo and bassoon maintain synaptic vesicle clustering without directly participating in vesicle exocytosis.	PCLO BSN	2.26e-05	2	166	2	20332206
Pubmed	Characterization of the interaction between the interferon-induced protein P56 and the Int6 protein encoded by a locus of insertion of the mouse mammary tumor virus.	EIF3E IFIT1	2.26e-05	2	166	2	10644362
Pubmed	Active zone density is conserved during synaptic growth but impaired in aged mice.	PCLO BSN	2.26e-05	2	166	2	21935939
Pubmed	NBPF is a potential DNA-binding transcription factor that is directly regulated by NF-κB.	NBPF26 NFKB1	2.26e-05	2	166	2	23939288
Pubmed	Synaptic activity controls localization and function of CtBP1 via binding to Bassoon and Piccolo.	PCLO BSN	2.26e-05	2	166	2	25652077
Pubmed	Constitutional translocation t(1;17)(p36.31-p36.13;q11.2-q12.1) in a neuroblastoma patient. Establishment of somatic cell hybrids and identification of PND/A12M2 on chromosome 1 and NF1/SCYA7 on chromosome 17 as breakpoint flanking single copy markers.	NBPF11 NBPF1	2.26e-05	2	166	2	7700633
Pubmed	Novel PMS2 pseudogenes can conceal recessive mutations causing a distinctive childhood cancer syndrome.	PMS2P1 PMS2	2.26e-05	2	166	2	15077197
Pubmed	SMC1α Substitutes for Many Meiotic Functions of SMC1β but Cannot Protect Telomeres from Damage.	SMC1A SMC1B	2.26e-05	2	166	2	29337080
Pubmed	Myosin Va is required for normal photoreceptor synaptic activity.	MYO5A MYO7A	2.26e-05	2	166	2	15316067
Pubmed	Cloning, mapping, expression, function, and mutation analyses of the human ortholog of the hamster putative tumor suppressor gene Doc-1.	POLA1 CDK2AP1	2.26e-05	2	166	2	9506968
Pubmed	Ror2-Src signaling in metastasis of mouse melanoma cells is inhibited by NRAGE.	MAGED1 ROR2	2.26e-05	2	166	2	23142633
Pubmed	IkappaBeta, a nuclear IkappaB protein, positively regulates the NF-kappaB-mediated expression of proinflammatory cytokines.	ANKRD42 NFKB1	2.26e-05	2	166	2	20547855
Pubmed	A new pathway of translational regulation mediated by eukaryotic initiation factor 3.	EIF3E IFIT1	2.26e-05	2	166	2	11118224
Pubmed	CLK2 mediates IκBα-independent early termination of NF-κB activation by inducing cytoplasmic redistribution and degradation.	CLK2 NFKB1	2.26e-05	2	166	2	38724505
Pubmed	Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.	PCLO BSN	2.26e-05	2	166	2	27321892
Pubmed	No symphony without bassoon and piccolo: changes in synaptic active zone proteins in Huntington's disease.	PCLO BSN	2.26e-05	2	166	2	32493491
Pubmed	A new meiosis-specific cohesin complex implicated in the cohesin code for homologous pairing.	SMC1A SYCP1 SMC1B	2.28e-05	12	166	3	21274006
Pubmed	The ubiquitin-dependent ATPase p97 removes cytotoxic trapped PARP1 from chromatin.	PSAT1 MAGED1 EIF3E CLIC4 ACTR2 IFRD1 AP2A2 PA2G4 CTNNA1 CGNL1	2.45e-05	400	166	10	35013556
Pubmed	Polε Instability Drives Replication Stress, Abnormal Development, and Tumorigenesis.	POLA1 SMC1A SMC1B	2.95e-05	13	166	3	29754823
Pubmed	Proteomic and Biochemical Comparison of the Cellular Interaction Partners of Human VPS33A and VPS33B.	SMC1A EIF3E POLR3A NBAS UPF2 CEP83 DNMBP CNOT1	2.98e-05	251	166	8	29778605
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	POLA1 SMC1A NELFB MCM4 CHD2 ECPAS IFI16 COPS2 TFAP2C PPP4R3A POLR3A PPP1R10 CCT6A GTF2F2 PA2G4 PIN1	3.09e-05	1014	166	16	32416067
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	EIF3E PABPC4L IFI16 SQOR POLR3A ITPR2 CCT6A CGNL1 CAPRIN1	3.14e-05	329	166	9	34316702
Pubmed	EZH2 interacts with HP1BP3 to epigenetically activate WNT7B that promotes temozolomide resistance in glioblastoma.	MYO5A MYO7A SMC1A RPS9 EIF3E MCM4 SQOR IFIT1 ACTR2 CCT6A MTHFD1 PA2G4 CCT6B CAPRIN1	3.40e-05	803	166	14	36517590
Pubmed	Kelch Domain of Gigaxonin Interacts with Intermediate Filament Proteins Affected in Giant Axonal Neuropathy.	RPS9 ZFC3H1 CCT6A MTHFD1 PLCB1 CCT6B PCNT	3.43e-05	187	166	7	26460568
Pubmed	Systems analysis of RhoGEF and RhoGAP regulatory proteins reveals spatially organized RAC1 signalling from integrin adhesions.	DOCK2 MAGED1 MYO5A RASGRF2 SMC1A HEATR1 ECPAS ARHGEF11 PPP1R10 AP2A2 PA2G4 FGD1 CTNNA1 ARHGAP18 DNMBP	3.63e-05	916	166	15	32203420
Pubmed	KAP1 facilitates reinstatement of heterochromatin after DNA replication.	POLA1 NELFB MCM4 HEATR1 URB2 COPS2 POLR3A NBAS CCT6A UPF2 PA2G4 PIN1 CNOT1	3.64e-05	704	166	13	29955894
Pubmed	Histone methyltransferase DOT1L coordinates AR and MYC stability in prostate cancer.	MAGED1 KRT18 MYO5A RPS9 UBXN6 ACTR2 CCT6A CTNNA1	4.25e-05	264	166	8	32814769
Pubmed	Network organization of the huntingtin proteomic interactome in mammalian brain.	MYO5A PCLO USP25 FIS1 CCT6A AP2A2 MTHFD1 EHHADH CCT6B SYT5 BSN DDX4	4.75e-05	621	166	12	22794259
Pubmed	NRAGE, a p75 neurotrophin receptor-interacting protein, induces caspase activation and cell death through a JNK-dependent mitochondrial pathway.	MAGED1 RASGRF2 ARHGEF11 FGD1	5.34e-05	43	166	4	12376548
Pubmed	TXLNA enhances TBK1 phosphorylation by suppressing PPM1B recruitment.	RPS9 FIS1 APOB ECPAS CCT6A TXLNG	5.52e-05	138	166	6	37506885
Pubmed	Proteomic analysis and identification of cellular interactors of the giant ubiquitin ligase HERC2.	SPTLC2 EIF3E BICD1 ITPR2 CTNNA1 TXLNG	5.74e-05	139	166	6	25476789
Pubmed	The prolyl isomerase Pin1 regulates the NF-kappaB signaling pathway and interleukin-8 expression in glioblastoma.	PIN1 NFKB1	6.77e-05	3	166	2	19668231
Pubmed	Roles of Pin1 as a Key Molecule for EMT Induction by Activation of STAT3 and NF-κB in Human Gallbladder Cancer.	PIN1 NFKB1	6.77e-05	3	166	2	30610554
Pubmed	Identification of NF-κB and PLCL2 as new susceptibility genes and highlights on a potential role of IRF8 through interferon signature modulation in systemic sclerosis.	NFKB1 PLCL2	6.77e-05	3	166	2	25880423
Pubmed	K25 (K25irs1), K26 (K25irs2), K27 (K25irs3), and K28 (K25irs4) represent the type I inner root sheath keratins of the human hair follicle.	KRT27 KRT25	6.77e-05	3	166	2	16874310
Pubmed	The role of Rab27a in the regulation of melanosome distribution within retinal pigment epithelial cells.	MYO5A MYO7A	6.77e-05	3	166	2	14978221
Pubmed	ERBB3-Binding Protein 1 (EBP1) Is a Novel Developmental Pluripotency-Associated-4 (DPPA4) Cofactor in Human Pluripotent Cells.	PA2G4 NFKB1	6.77e-05	3	166	2	29327467
Pubmed	Novel meiosis-specific isoform of mammalian SMC1.	SMC1A SMC1B	6.77e-05	3	166	2	11564881
Pubmed	Tissue-specific subunit of the mouse cytosolic chaperonin-containing TCP-1.	CCT6A CCT6B	6.77e-05	3	166	2	9013858
Pubmed	Myrip uses distinct domains in the cellular activation of myosin VA and myosin VIIA in melanosome transport.	MYO5A MYO7A	6.77e-05	3	166	2	19317802
Pubmed	p12(DOC-1), a growth suppressor, associates with DNA polymerase alpha/primase.	POLA1 CDK2AP1	6.77e-05	3	166	2	10877824
Pubmed	Receptor-mediated clustering of FIP200 bypasses the role of LC3 lipidation in autophagy.	DOCK2 RPS9 HEATR1 URB2 ACTR2 POLR3A AP4E1 CCT6A NBPF15 MTHFD1	7.08e-05	454	166	10	33226137
Pubmed	Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.	MYO5A SPTLC2 POLA1 EIF3E USP25 HEATR1 URB2 ECPAS GGCX GTF2F2 AP2A2 OS9 PCNT	7.30e-05	754	166	13	33060197
Pubmed	Acetylation of ELF5 suppresses breast cancer progression by promoting its degradation and targeting CCND1.	SMC1A EIF3E MCM4 ECPAS IFIT1 TFAP2C CCT6A IFRD1 AP2A2 PA2G4 BSN TXLNG	7.65e-05	653	166	12	33742100
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	DOCK2 SMC1A NELFB MCM4 ECPAS IFI16 ACTR2 PPP4R3A CCT6A GTF2F2 MTHFD1 PA2G4 PIN1 CNOT1 TXLNG CAPRIN1	8.31e-05	1103	166	16	34189442
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	PDXDC1 PMS2 POLA1 CLIC4 HEATR1 ECPAS GTF2F2 OSBPL9 MACF1 CAPRIN1	9.74e-05	472	166	10	38943005
Pubmed	HACE1 mediated K27 ubiquitin linkage leads to YB-1 protein secretion.	AP2A2 PA2G4 CAPRIN1	9.78e-05	19	166	3	26343856
Pubmed	Analysis of interaction partners for eukaryotic translation elongation factor 1A M-domain by functional proteomics.	IFT172 DNAH17 MACF1	1.15e-04	20	166	3	21689717
Pubmed	Proteomic analysis of in vivo phosphorylated synaptic proteins.	PCLO PLCB1 CTNNA1 BSN	1.22e-04	53	166	4	15572359
Pubmed	Comprehensive identification of phosphorylation sites in postsynaptic density preparations.	MYO5A PCLO RPS9 PA2G4 MACF1 BSN CAPRIN1	1.29e-04	231	166	7	16452087
Pubmed	An orthogonal proteomic-genomic screen identifies AIM2 as a cytoplasmic DNA sensor for the inflammasome.	IFI16 IFIT1 PYHIN1	1.33e-04	21	166	3	19158679
Pubmed	Abnormal taste perception in mice lacking the type 3 inositol 1,4,5-trisphosphate receptor.	ITPR2 PLCB1	1.35e-04	4	166	2	17925404
Cytoband	1q21.1	NBPF8 ANKRD35 NBPF11 NBPF9 NBPF10 NBPF14	1.06e-07	62	166	6	1q21.1
Cytoband	Ensembl 112 genes in cytogenetic band chr1q21	ANKRD35 NBPF12 NBPF11 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14	1.21e-04	404	166	8	chr1q21
Cytoband	Ensembl 112 genes in cytogenetic band chr15q21	MYO5A COPS2 SQOR AP4E1 CGNL1	4.82e-04	177	166	5	chr15q21
GeneFamily	Neuroblastoma breakpoint family	NBPF8 NBPF12 NBPF26 NBPF11 NBPF1 NBPF19 NBPF15 NBPF9 NBPF10 NBPF14	4.05e-17	23	108	10	662
GeneFamily	Zinc fingers\|Zinc fingers PARP-type\|Poly(ADP-ribose) polymerases	PCLO ZFC3H1 BSN	8.95e-05	15	108	3	26
GeneFamily	Phospholipases\|C2 domain containing phospholipases	PLCL2 PLCB1 PLA2G4F	1.87e-04	19	108	3	832
GeneFamily	Pyrin domain containing\|Pyrin and HIN domain family	IFI16 PYHIN1	3.49e-04	5	108	2	995
GeneFamily	Keratins, type I	KRT18 KRT27 KRT25	6.09e-04	28	108	3	608
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	RASGRF2 ARHGEF11 FGD1 DNMBP	6.53e-04	66	108	4	722
GeneFamily	Structural maintenance of chromosomes proteins\|Cohesin complex	SMC1A SMC1B	7.28e-04	7	108	2	761
GeneFamily	Cohesin complex	SMC1A SMC1B	9.67e-04	8	108	2	1060
GeneFamily	Chaperonins	CCT6A CCT6B	3.53e-03	15	108	2	587
Coexpression	GSE16450_CTRL_VS_IFNA_12H_STIM_IMMATURE_NEURON_CELL_LINE_UP	DOCK2 PMS2P1 RASGRF2 POLA1 ADNP2 FBXL17 URB2 POLR3A PPP1R10 NBAS CCT6B PCNT	5.15e-09	197	166	12	M7403
Coexpression	GSE41867_NAIVE_VS_DAY15_LCMV_CONE13_EFFECTOR_CD8_TCELL_DN	MAGED1 CFAP36 PASD1 AP4E1 NUDT12 CCT6A AP2A2 PIN1 CNOT1 CAPRIN1	5.01e-07	195	166	10	M9508
Coexpression	CREIGHTON_ENDOCRINE_THERAPY_RESISTANCE_1	MYO5A RPS9 MCM4 COPS2 TFAP2C CCDC83 MTHFD1 SYTL5 PA2G4 CLK2 NBPF9 PLCB1 OLFM1 OS9 ACSS3	1.69e-06	534	166	15	M12522
ToppCell	COVID-19_Mild-CD4+_T_activated\|COVID-19_Mild / Disease condition and Cell class	TUT4 NBPF11 ECPAS IFIT1 PPP4R3A NBPF1 LINS1 NBPF15 NBPF10	2.92e-08	182	166	9	877b6e611626628e709568747512f2827ebb2795
ToppCell	Control_saline-Endothelial-Endothelial-Alv_Gen_Intermediate\|Control_saline / Treatment groups by lineage, cell group, cell type	CLIC4 PARVB ITGA4 IFI16 IFIT1 CDK2AP1 CTNNA1 ARHGAP18	8.76e-07	200	166	8	041a34080120c9f613373c20dcc366292f558040
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 RASGRF2 ITGA4 IFI16 PYHIN1 RASGRP1 PLCL2 PLCB1	8.76e-07	200	166	8	02c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF12 NBPF11 PPP4R3A NBPF1 NBPF15 NBPF10	1.18e-06	144	166	7	984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell	Control-B_naive-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF11 PPP4R3A NBPF1 NBPF15 NBPF10 MACF1	1.93e-06	155	166	7	0a78d1cab2bdba2dc8a74cdf35b5a0192370c4b5
ToppCell	control-Epithelial-Ionocyte\|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RASGRF2 FAT3 PABPC4L PARVB ITPR2 CGNL1 DDX4	2.92e-06	165	166	7	5cfba9a46bd8ceeca74a6493057b4d38af6b06fe
ToppCell	Control-B_intermediate-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF12 NBPF11 PPP4R3A NBPF1 NBPF15 NBPF10	3.16e-06	167	166	7	948504367ecf58144d9dd74d2ec531358fc4b309
ToppCell	control-Epithelial-Ionocyte\|Epithelial / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	RASGRF2 FAT3 PABPC4L PARVB ITPR2 CGNL1 DDX4	3.29e-06	168	166	7	327b02f19f4a8607c033203824fdc60a1254331f
ToppCell	Control-B_naive-1\|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF11 PPP4R3A NBPF1 NBPF15 NBPF10 MACF1	3.70e-06	171	166	7	d18855b24aadea38fd1e4592f945cf15b85e05f1
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 PARVB ITPR2 LRRC9 SLIT2 LOXHD1 ARHGAP18	4.31e-06	175	166	7	77c16e615c0fb9c83f29d7e0a547be72635fac81
ToppCell	droplet-Spleen-nan-18m\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 CHD2 ITGA4 ITPR2 PYHIN1 PPP1R10 MACF1	5.57e-06	182	166	7	eeb5dfa4539e9ca5220f26bc2b65717ddcf13b6c
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 TFAP2C NBPF10 CGNL1 NBPF14 ACSS3	6.42e-06	186	166	7	41e03be964044dae690d566bd078dab3d8045eba
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	MCM4 HEATR1 ITGA4 ITPR2 NBAS MACF1 DOP1B	6.42e-06	186	166	7	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	COPD-Myeloid-ncMonocyte\|Myeloid / Disease state, Lineage and Cell class	NBPF26 ITGA4 HERC2P3 NBPF19 PLCB1 DNMBP NBPF14	7.38e-06	190	166	7	ed978cd5d9da87b49878a330e362762c487f849f
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO5A MYO7A SPTLC2 PARVB AP2A2 ARHGAP18 DNMBP	7.38e-06	190	166	7	2d54fca50593fbd11fe13fc2bfaf937a05db776d
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25\|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)	TUT4 EIF1B CHD2 CFAP210 PPP4R3A DNMBP CNOT1	7.64e-06	191	166	7	1ecd9849d14d5ebf3daf610e83fb50820cafd3ed
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	TUT4 EIF3E ZFC3H1 ITPR2 SYNJ2 PLCB1 ACSS3	8.18e-06	193	166	7	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	COPD-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	MYO5A RASGRF2 HEATR1 URB2 SYNJ2 PLCB1 OLFM1	8.46e-06	194	166	7	8dcde77767b23e75360adb316cdccf56a00e3726
ToppCell	Adult-Immune-T_lymphocyte-D231\|Adult / Lineage, Cell type, age group and donor	DOCK2 RASGRF2 ITGA4 PYHIN1 RASGRP1 PLCB1 IL26	8.46e-06	194	166	7	5c1dca33f382f37a7deb23e573578343c3b54986
ToppCell	B_cells-ISG-high_B_cells\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 SPTLC2 NT5C3A USP25 IFI16 IFIT1 PHF11	8.74e-06	195	166	7	b64d9e1a8834401b4dc501566546647754ae21fc
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDXDC1 GGCX IGSF10 PPP1R10 AP2A2 MACF1 CAPRIN1	9.04e-06	196	166	7	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	Mild-CD4+_T_activated\|World / Disease group and Cell class	BCL2L14 NT5C3A ITGA4 IFI16 SQOR IFIT1 PHF11	9.04e-06	196	166	7	417b4fc2e4388f34c410576131b02936f93e46b6
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDXDC1 GGCX IGSF10 PPP1R10 AP2A2 MACF1 CAPRIN1	9.04e-06	196	166	7	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 RASGRF2 ITGA4 IFI16 RASGRP1 PLCL2 PLCB1	9.98e-06	199	166	7	0d6463e368fd611a17327322413fad145f3c7f32
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 ITGA4 PYHIN1 RASGRP1 PLCL2 PLCB1 IL26	9.98e-06	199	166	7	fbdde57dd88656621801e65ee2818251588f3874
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_CTL\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 ITGA4 IFI16 PYHIN1 RASGRP1 PLCL2 PLCB1	9.98e-06	199	166	7	eb188b0b457136b6ee485d3b3052baa30d9c0002
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CLIC4 PARVB IFI16 IFIT1 MACF1 CTNNA1 ARHGAP18	1.03e-05	200	166	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TUT4 PARVB IFI16 IFIT1 MACF1 ARHGAP18 PCNT	1.03e-05	200	166	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 RASGRF2 ITGA4 PYHIN1 RASGRP1 PLCL2 PLCB1	1.03e-05	200	166	7	be9a43acc2f926b9433ab3f018b911b03896a924
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CLIC4 PARVB IFI16 IFIT1 MACF1 CTNNA1 ARHGAP18	1.03e-05	200	166	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TUT4 SPTLC2 PARVB IFI16 IFIT1 MACF1 ARHGAP18	1.03e-05	200	166	7	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Alv_Gen_Intermediate\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	CLIC4 PARVB IFI16 IFIT1 CDK2AP1 CTNNA1 ARHGAP18	1.03e-05	200	166	7	b70b7adb7c187e6253c7f0bb4c1f09c85ef7142c
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 RASGRF2 ITGA4 PYHIN1 RASGRP1 PLCL2 PLCB1	1.03e-05	200	166	7	c6c2b39359c65c9444987d02d1c899dff2ad1366
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 ITGA4 IFI16 PYHIN1 RASGRP1 PLCL2 PLCB1	1.03e-05	200	166	7	66fb892bda1d29e67a65717e85f2ec221f520b2a
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	DOCK2 RASGRF2 ITGA4 PYHIN1 RASGRP1 PLCL2 PLCB1	1.03e-05	200	166	7	9ef322486e46e4ff05a8cbe06cf8019e996c94b3
ToppCell	Mild/Remission-B_naive-1\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 NBPF11 PPP4R3A NBPF1 NBPF15 NBPF10	1.62e-05	143	166	6	bd3f5fbd4e9e4dc414682db5607494f3ce988deb
ToppCell	mild_COVID-19_(asymptomatic)-NK_CD56bright\|mild_COVID-19_(asymptomatic) / disease group, cell group and cell class (v2)	BICD1 IGSF10 FSIP2 EHHADH SGSM2 B4GALT4	2.21e-05	151	166	6	2470162f4b56bc505db166a6eb0fa54847759df8
ToppCell	Severe-B_naive-1\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	TUT4 PPP4R3A NBPF1 NBPF15 NBPF10 MACF1	2.95e-05	159	166	6	2881b054bbeb479221ee3c38bbd9b0815b123579
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAOB DBT SLC3A1 HPD MTHFD1 EHHADH	3.51e-05	164	166	6	90afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell	NS-control-d_0-4-Epithelial-Ionocyte\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	RASGRF2 FAT3 PABPC4L PARVB ITPR2 DDX4	3.75e-05	166	166	6	6d9fb239f69ba519844f593c00d515e1aac4ff50
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A ROR2 APOB SLC3A1 VILL EHHADH	3.88e-05	167	166	6	ed7e785dcd25777f64e0c2596ada4f5a5ea17121
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-T_cells-SELL+_CD4_T\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RASGRF2 RASGRP1 DNAH17 PLCL2 BSN GP1BA	3.88e-05	167	166	6	484de3ca4a905067c18d06995601479eef8fc15e
ToppCell	Tuft-tuft-1\|World / Class top	RASGRF2 MYO7A WHAMM PARVB TFAP2C NBAS	4.01e-05	168	166	6	8ddc2ec483ed2c6c0fb2ae521c6861ceb6d32e34
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Outer_Medullary_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 PARVB ITPR2 LRRC9 SLIT2 ARHGAP18	4.15e-05	169	166	6	2a21f2cef959526bfe3c8f081f4f7e9dd4e01a37
ToppCell	droplet-Kidney-nan-18m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A ROR2 APOB SLC3A1 VILL EHHADH	4.15e-05	169	166	6	f00741203efa0b948db7223ee8c19bdd0918258a
ToppCell	droplet-Kidney-nan-21m-Epithelial-brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A ROR2 APOB SLC3A1 VILL EHHADH	4.43e-05	171	166	6	007f148f4611ea1826edfa9f91ced36541ad9f5a
ToppCell	droplet-Kidney-nan-21m-Epithelial-Epcam____brush_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO5A ROR2 APOB SLC3A1 VILL EHHADH	4.43e-05	171	166	6	8e7223ba447947cdf4e1c82a52fd90439cf3d8f6
ToppCell	facs-Skin-Skin_Anagen-18m-Epithelial-epidermal_cell\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKRD35 LAMA1 TFAP2C IFRD1 PLA2G4F HSF2	4.73e-05	173	166	6	0f9c1d3298e59e6d22bb3306f0f445f490be8bbd
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 PARVB ITPR2 LRRC9 SLIT2 ARHGAP18	4.73e-05	173	166	6	0bc2aacae60c6d3276b0949eb0748b4ac1f56e54
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 PARVB ITPR2 LRRC9 SLIT2 ARHGAP18	4.88e-05	174	166	6	5f4436863a40f8bca46e2989bca66c02b6be88d4
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_1\|Classical_Monocyte / Disease condition and Cell class	TUT4 ECPAS SQOR PPP4R3A NBPF1 NBPF10	5.04e-05	175	166	6	35ea2ed93538e6bf803029fcf7d9243f93e7733d
ToppCell	Bronchial_Biopsy-Epithelial-Ionocytes\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	WDR88 FAT3 APOB PARVB ITPR2 DDX4	5.04e-05	175	166	6	13b8f7dc38c90b74d4a20a84a8705d8e2ec244f6
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 PARVB LRRC9 SLIT2 LOXHD1 ARHGAP18	5.20e-05	176	166	6	25ebc8716aa44e44fce577701e3e82c6745a75ab
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 PARVB ITPR2 SLIT2 LOXHD1 ARHGAP18	5.20e-05	176	166	6	c2c4306476989bc2fb30dab00250ef7915842f13
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SPTLC2 ROR2 LRRC9 SLIT2 PLCL2 ARHGAP18	5.37e-05	177	166	6	f35b04c3557ebbdeba37dec54c8f45880eafb422
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet-Megakaryocyte/Platelet_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD35 NT5C3A PARVB IFIT1 ARHGAP18 GP1BA	5.54e-05	178	166	6	9e1f2596fcea5b79cc50b58d83706bb8605e224f
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD35 NT5C3A PARVB IFIT1 ARHGAP18 GP1BA	5.54e-05	178	166	6	aa659bd283c4dfbe292cd8698bbf6b1999ca3314
ToppCell	PND10-Immune-Immune_Myeloid-Megakaryocyte/Platelet\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANKRD35 NT5C3A PARVB IFIT1 ARHGAP18 GP1BA	5.54e-05	178	166	6	bf1d273802a4f42e52ea1bd2a0cae2039559c093
ToppCell	Globus_pallidus-Macroglia-POLYDENDROCYTE\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	PSAT1 EIF1B RNF144A ITPR2 CCT6A PA2G4	5.54e-05	178	166	6	b1357ceb84b83fab53c0394c1af73cbd009f571a
ToppCell	T_cells-ISG-high_CD4+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 NT5C3A IFI16 SQOR IFIT1 PHF11	5.71e-05	179	166	6	af35ef8a7768cee0c2af0590e5bec35cee6a4714
ToppCell	3'-Distal_airway-Immune_Lymphocytic-Lymphocytic_T/NK-CD4-positive,_alpha-beta_T_cell-CD4_T_cells-CD4_T_cells_L.1.1.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TUT4 RASGRF2 FBXL17 POLR3A LINS1 CEP19	5.71e-05	179	166	6	6bbb32d7e582a96cb3cfc3eb911b05d518e7d5e9
ToppCell	NS-moderate-d_0-4-Lymphoid-CTL\|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	DOCK2 RASGRF2 ITGA4 NBPF11 FCHO1 PYHIN1	6.08e-05	181	166	6	7fb3c1d29c542a3cea7fa654432d501d82df138f
ToppCell	COVID-19_Severe-Classical_Monocyte-cMono_1\|COVID-19_Severe / Disease condition and Cell class	TUT4 ECPAS SQOR PPP4R3A NBPF1 NBPF10	6.08e-05	181	166	6	0d07a67e8ee3bca687b378afbc4044434e63556d
ToppCell	COVID-19_Convalescent\|World / Disease condition and Cell class	RPS9 NBPF26 NBPF19 NBPF15 CDK2AP1 NBPF14	6.08e-05	181	166	6	a62115a8da486fc61225901c72b1ec70bcaf4c36
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	CHD2 PPP1R10 NBPF15 NFKB1 PLCB1 MACF1	6.08e-05	181	166	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	COVID-19_Mild-Lymphoid_T/NK-CD4+_T_activated\|COVID-19_Mild / Disease group, lineage and cell class	TUT4 RASGRF2 IFIT1 PPP4R3A LINS1 NBPF15	6.46e-05	183	166	6	7717fce227b4e02ed41baad8ae7dd2e22bd7c13e
ToppCell	droplet-Spleen-nan-18m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 CHD2 ITPR2 PYHIN1 PPP1R10 MACF1	6.46e-05	183	166	6	28cbf909424f3be4491d49832f0aca0386560814
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	TUT4 ECPAS IFIT1 PPP4R3A NBPF10 MACF1	6.46e-05	183	166	6	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	Mild/Remission-B_intermediate-10\|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)	RNF144A PYHIN1 RASGRP1 NBPF10 MACF1 DNMBP	6.46e-05	183	166	6	278064c9f0582463b83bf156d34e77f60187613b
ToppCell	droplet-Spleen-nan-18m-Lymphocytic-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 CHD2 ITPR2 PYHIN1 PPP1R10 MACF1	6.46e-05	183	166	6	3fa608aa6b119869ec3280dc388dfee57160e63a
ToppCell	TCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-4\|TCGA-Pancreas / Sample_Type by Project: Shred V9	MYO5A PABPC4L ITGA4 ITPR2 SLIT2 ACSS3	6.65e-05	184	166	6	67164bb6bcae7322cb89b585c7aa10bce35b0ecd
ToppCell	droplet-Marrow-nan-3m\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TUT4 ITGA4 PYHIN1 PPP1R10 CCT6A MACF1	6.65e-05	184	166	6	1154a5ad7b8512272b7476f949ddac350910bfb7
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	MCM4 HEATR1 ITGA4 NBAS MACF1 DOP1B	6.86e-05	185	166	6	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)-D175\|Adult / Lineage, Cell type, age group and donor	DOCK2 MYO5A MYO7A PARVB AP2A2 ARHGAP18	6.86e-05	185	166	6	ab5704b96f1d368911308797d10c7c52766ab134
ToppCell	Control-T_cells-CD8+_T_cells\|Control / group, cell type (main and fine annotations)	DOCK2 ITGA4 PYHIN1 RASGRP1 PLCL2 PLCB1	6.86e-05	185	166	6	02ab64c0166c0646d1d4c6ed110ef0b75a1096d0
ToppCell	pdx\|World / Sample and Cell Type and Tumor Cluster (all cells)	BCL2L14 RASGRF2 BICD1 ITPR2 PLCB1 ACSS3	7.06e-05	186	166	6	de8e538c8767d41b8a52f5e58ba1affd4e7244c4
ToppCell	pdx-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	BCL2L14 RASGRF2 BICD1 ITPR2 PLCB1 ACSS3	7.06e-05	186	166	6	0b88a87158a9ca8de3bf40a4ff1687150707a5f0
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.28e-05	187	166	6	dd1d91f101b837bba513f77defa6e6902b2c0570
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.28e-05	187	166	6	4d2115a05ec36dd179ca1d4a525f2d4501aea557
ToppCell	Anterior_Cingulate_gyrus_(CgG)-Non-neuronal-Macroglial-Astro\|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.28e-05	187	166	6	ae90c263f80c36a410150d499e268d198944a3d9
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.28e-05	187	166	6	5d3d68519c8e19f10c29f9d81712125be78ca15a
ToppCell	Control-T_cells\|Control / group, cell type (main and fine annotations)	DOCK2 ITGA4 IFI16 PYHIN1 RASGRP1 PLCL2	7.28e-05	187	166	6	f4e8e0eba58da89b56587667555a5d4754e108c7
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.28e-05	187	166	6	5c73010fe4c85fb5cc1273f5504821229ca0cc4b
ToppCell	Mid-temporal_gyrus_(MTG)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.28e-05	187	166	6	93c78fc7f126132eb84feb47be2c4e8c568b9e91
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	CHD2 PPP1R10 IFRD1 NFKB1 PLCB1 MACF1	7.49e-05	188	166	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	human_hepatoblastoma-NK.T_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	DOCK2 ITGA4 IFI16 PYHIN1 RASGRP1 PLCL2	7.49e-05	188	166	6	71b7599e7e1d63cc0c8518c0501533755951d58f
ToppCell	T_cells-ISG-high_CD4+_T_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	BCL2L14 NT5C3A IFI16 SQOR IFIT1 PHF11	7.49e-05	188	166	6	6f8946d4710f6e32c937213f99b790b098b8819c
ToppCell	343B-Lymphocytic-ILC-ILC-1\|343B / Donor, Lineage, Cell class and subclass (all cells)	CXorf38 MYO7A VPS50 HEATR1 PYHIN1 RASGRP1	7.49e-05	188	166	6	8f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell	COPD-Myeloid-cMonocyte\|COPD / Disease state, Lineage and Cell class	NBPF26 NBPF19 NBPF10 PLCB1 DNMBP NBPF14	7.72e-05	189	166	6	d29f3a0bd23e6eb46389e6eb7ef21851c7b57545
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAOB FAT3 ROR2 IGSF10 SLIT2 ACSS3	7.72e-05	189	166	6	a153b83314cf52808f685296cff8c95af3f4983d
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Matrix_Fibroblast-Diff_MatrixFB\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAOB ROR2 IGSF10 SLIT2 OLFM1 ACSS3	7.72e-05	189	166	6	e9d5e858e320c6e9913c1ea6a54967d21eda605f
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	NBPF26 HERC2P3 NBPF19 PLCB1 DNMBP NBPF14	7.94e-05	190	166	6	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.94e-05	190	166	6	3a55cc5dc2549788bfe55f649686887b21a1fdd2
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 MYO5A MYO7A ITPR2 AP2A2 ARHGAP18	7.94e-05	190	166	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	DOCK2 RASGRF2 ITGA4 PYHIN1 RASGRP1 PLCL2	7.94e-05	190	166	6	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	Somatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	LAMA1 NBPF26 NBPF10 CGNL1 NBPF14 ACSS3	7.94e-05	190	166	6	1c3d601422efa60fad8565f9ccd9032b847e4a91
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	EIF3E ZC3H12B NBPF19 LINS1 PA2G4 HSF2	8.18e-05	191	166	6	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Matrix_Fibroblast-Activated_MatrixFB\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MAOB FAT3 ROR2 IGSF10 SLIT2 ACSS3	8.18e-05	191	166	6	b13229bb7f3713a392271aaf5dbae3edd1b9fe5a
ToppCell	COVID-19-kidney-Proliferating_T_cell\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 ITGA4 PYHIN1 RASGRP1 FBXO43 IL26	8.18e-05	191	166	6	bae388e0e9447d576e68465d73d8313ef6925ffa
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	MCM4 HEATR1 ITGA4 NBAS MACF1 DOP1B	8.18e-05	191	166	6	9454f642c3621370fa23640b631301346b300950
Drug	Tacrine hydrochloride hydrate [1684-40-8]; Up 200; 15.8uM; HL60; HT_HG-U133A	CLIC4 MCM4 ITGA4 DBT PPP4R3A SGSM2 SLITRK5 CTNNA1 TXLNG CAPRIN1	1.42e-06	194	163	10	1278_UP
Drug	Metrizamide [31112-62-6]; Up 200; 5uM; HL60; HT_HG-U133A	CLIC4 DBT ITPR2 GTF2F2 DNAH17 PLCB1 ZNF75D HSF2 CAPRIN1 B4GALT4	1.49e-06	195	163	10	1318_UP
Drug	5155877; Down 200; 10uM; MCF7; HT_HG-U133A	TUT4 POLA1 SMC1A MCM4 DBT OVGP1 COMMD4 CLK2 CCT6B OLFM1	1.64e-06	197	163	10	6549_DN
Drug	Trichlormethiazide [133-67-5]; Down 200; 10.6uM; MCF7; HT_HG-U133A	SMC1A TBC1D2 ARHGEF11 PPP4R3A BICD1 COMMD4 AP2A2 PLCB1 FGD1	1.29e-05	197	163	9	3337_DN
Drug	Pesticides	NBPF8 NBPF12 NBPF11 NBPF1 NBPF15 NBPF9 NBPF10 NBPF14	1.29e-05	150	163	8	ctd:D010575
Disease	sleep apnea measurement, obstructive sleep apnea	SMCO2 NBAS PLCB1	6.65e-04	33	153	3	EFO_0003918, EFO_0007817
Disease	Schizophrenia	PSAT1 MAOB LAMA1 ADNP2 ARHGEF11 ACTR2 HP MTHFD1 PLCL2 PLCB1 CGNL1 ARHGAP18 PCNT	7.21e-04	883	153	13	C0036341
Disease	response to methylphenidate	RASGRF2 SQOR	9.39e-04	9	153	2	GO_0036271
Disease	thalamus volume	FAT3 BICD1 NFKB1 MACF1	1.02e-03	85	153	4	EFO_0006935
Disease	cardiovascular system disease (is_marker_for)	APOB HP	1.17e-03	10	153	2	DOID:1287 (is_marker_for)
Disease	cystic kidney disease (implicated_via_orthology)	IFT172 SLIT2	1.17e-03	10	153	2	DOID:2975 (implicated_via_orthology)
Disease	PR domain zinc finger protein 1 measurement	EHHADH BSN	1.42e-03	11	153	2	EFO_0801904
Disease	cocaine use	CHRNA6 TFAP2C	1.42e-03	11	153	2	C3496069
Disease	beta thalassemia (is_marker_for)	APOB HP	1.42e-03	11	153	2	DOID:12241 (is_marker_for)
Disease	pars orbitalis volume measurement	SLIT2 ACSS3	1.42e-03	11	153	2	EFO_0010320
Disease	campesterol measurement	SLC3A1 OLFM1	1.42e-03	11	153	2	EFO_0020008
Disease	cleft palate (is_implicated_in)	ROR2 MTHFD1	1.70e-03	12	153	2	DOID:674 (is_implicated_in)
Disease	Alzheimer disease, APOE carrier status	PMS2 ROR2 CHD2 NBAS	1.72e-03	98	153	4	EFO_0007659, MONDO_0004975
Disease	plasma beta-amyloid 1-42 measurement	FBXL17 ACSS3	2.01e-03	13	153	2	EFO_0005660
Disease	pulse pressure measurement, social deprivation	PLCL2 ACSS3	2.33e-03	14	153	2	EFO_0005763, EFO_0009696
Disease	Down syndrome (implicated_via_orthology)	SYNJ2 DOP1B	2.68e-03	15	153	2	DOID:14250 (implicated_via_orthology)
Disease	amenorrhea, response to antineoplastic agent	VPS50 APOB	2.68e-03	15	153	2	EFO_0010269, GO_0097327
Disease	lipoprotein A measurement	APOB SYNJ2 PHF11 SPRYD4	2.80e-03	112	153	4	EFO_0006925
Disease	congenital myasthenic syndrome (implicated_via_orthology)	CHRNA6 SYT5	3.06e-03	16	153	2	DOID:3635 (implicated_via_orthology)
Disease	non-alcoholic steatohepatitis (biomarker_via_orthology)	KRT18 NFKB1	3.45e-03	17	153	2	DOID:0080547 (biomarker_via_orthology)
Disease	Bipolar Disorder	CHRNA6 MAOB PCLO RASGRP1 MTHFD1 EHHADH PLCB1 PCNT	3.54e-03	477	153	8	C0005586
Disease	cholesterol to total lipids in IDL percentage	PDXDC1 APOB MACF1	3.77e-03	60	153	3	EFO_0022233
Disease	response to methotrexate, neurotoxicity	MACF1 PKN1	4.31e-03	19	153	2	EFO_0011057, GO_0031427
Disease	sphingomyelin 22:0 measurement	HEATR1 OLFM1	4.77e-03	20	153	2	EFO_0010395
Disease	urate measurement, bone density	BCL2L14 TBC1D2 ITPR2 FSIP2 CEP83 PLCB1 OLFM1 EIF2AK4 CTNNA1	5.14e-03	619	153	9	EFO_0003923, EFO_0004531

Protein segments in the cluster

Peptide	Gene	Start	Entry
VLIIGELLKQADLYI	CCT6A	96	P40227
VKSLLQEGIYLILDL	URB2	1466	Q14146
KIGYLNDRVDELLEK	NT5C3A	296	Q9H0P0
ERGLLKTLQKLDEYL	CLIC4	141	Q9Y696
ALQNYIKEALIVIDK	TFAP2C	411	Q92754
EYGLVVLEEKLTLKQ	BICD1	36	Q96G01
DDLKKGTQLLEIYAL	COPS2	186	P61201
GLKQIKYLVLDEADR	DDX4	436	Q9NQI0
LELNDELEKQIVYLK	CCDC169	66	A6NNP5
AIILIYESEIKGKIR	CEP19	16	Q96LK0
QLVKYGLKDLEEVVG	EIF2AK4	1286	Q9P2K8
AKLLNVGYLEALKEE	B4GALT4	171	O60513
YKEAARLEINVLEKI	CLK2	201	P49760
VEKLLEGYLKEIGIN	CFAP36	61	Q96G28
ELLQKVITLYKDALA	RASGRP1	101	O95267
EKQLAALGDILSKYE	ARHGEF11	451	O15085
EQILAKIVELLKYSG	BCL2L14	206	Q9BZR8
KIVELLKYSGDQLER	BCL2L14	211	Q9BZR8
AIALLEIYEKDEKIQ	DNMBP	876	Q6XZF7
EIGKLKQLLYQATEE	ANKRD35	806	Q8N283
EGYQKLVVLQDEKLE	CEP83	386	Q9Y592
FLLEVGIVKEEQLKV	EIF1B	96	O60739
LKTVLELQYVLDKLG	CAPRIN1	146	Q14444
LKQLYLERVLKGDVE	ACTR2	321	P61160
KEKLGEREVYLAILA	ADNP2	831	Q6IQ32
QNAVKLIDKGSYLEI	CCDC83	201	Q8IWF9
EEIVLKVAILAEKYA	AP2A2	421	O94973
LAAVKLLEELQKYDI	ANKRD42	316	Q8N9B4
IVNLVGKIAELAEKY	AP4E1	426	Q9UPM8
ALALENEGYIKKLLE	PPP4R3A	161	Q6IN85
VLDLLQIPYEKNDEK	ITPR2	1216	Q14571
KVLGYDETIKAELVL	PALM2	296	Q8IXS6
KKLTEADAYLQILIE	OSBPL9	121	Q96SU4
LGYNKIQDITELEKL	LRRC9	1301	Q6ZRR7
LAKELGLETYKVNEV	MAOB	71	P27338
KDGRILKEDILNYLE	DBT	196	P11182
QDYILKEGDLVKIDL	PA2G4	96	Q9UQ80
EGILKVVKALDYEQL	DSG3	326	P32926
KLQDLIKDVLRYGEE	FCHO1	91	O14526
YEHEDIKKGILLQLF	MCM4	471	P33991
LLNIKVKLEAEIATY	KRT18	366	P05783
EVLEELYKKVLLGAT	LINS1	6	Q8NG48
IQLKEIDKEEHLYIL	MAGED1	526	Q9Y5V3
LTLYVGKKQLVEIEK	HP	221	P00738
GDIRDELKKLYAQLE	GPR179	676	Q6PRD1
SEYKGILQLDKVDVI	GINM1	291	Q9NU53
LKALETYEIIFKIVG	DOP1B	81	Q9Y3R5
YVAGLDVGIIKKIEL	LOXHD1	1476	Q8IVV2
EIDAKLKYLELGITQ	BSN	2971	Q9UPA5
GELLIAVEELLNKLY	FSIP2	2481	Q5CZC0
KIYAKDIIINILETI	FSIP2	2736	Q5CZC0
EVGIKKEEELFLYLL	EHHADH	246	Q08426
NEKEKELQLEYLLGA	ECPAS	1681	Q5VYK3
KYNDDIRKGIVLLEE	FIS1	46	Q9Y3D6
GIILEVLEAYRDKKE	PCLO	2311	Q9Y6V0
TKEEALELINGYIQK	PIN1	81	Q13526
LKKVNYIKILVEDEL	PDXDC1	371	Q6P996
PVLEEYKADAKLVLQ	OLFM1	166	Q99784
AVKELYSQLGEKLEQ	NELFB	536	Q8WX92
ATNIDLKLKDYGVDL	PMS2P3	126	Q13401
LKLKDYGVDLIEVSD	PMS2P3	131	Q13401
YEQLLDIKVHLEKEI	KRT27	371	Q7Z3Y8
GQKLEYEQLLDIKLH	KRT25	361	Q7Z3Z0
ATNIDLKLKDYGVDL	PMS2P1	251	A4D2B8
VKNVLELTLYDKDIL	PLA2G4F	106	Q68DD2
NELLKEYLVTLAKGD	NBAS	951	A2RRP1
EQYLGLALDVDRIKK	NBPF1	1011	Q3BBV0
EIELLKIENRNLYGK	PCNT	691	O95613
KLYKLLEIDIDGVFK	POLA1	1031	P09884
IQDAELLVKGYEIKL	MACF1	1166	Q9UPN3
LLVKGYEIKLSQEEV	MACF1	1171	Q9UPN3
SVLIGEQYLKDELKK	MACF1	4756	Q9UPN3
CLKQYVELLIKEGLE	RNF144A	46	P50876
YLIDIKTIAIVDLIG	IFT172	461	Q9UG01
AEKELVQSLKEYILV	P4HA2	36	O15460
VQSLKEYILVEEAKL	P4HA2	41	O15460
LEEDLYDGQVLQKLL	PARVB	111	Q9HBI1
LPDEEKDEVYQKIIL	PASD1	81	Q8IV76
GIEKLDILTELKYRN	FBXO43	491	Q4G163
YDKAEIDLLIIGSKV	CHRNA6	181	Q15825
YELEEKIVSLIKNLL	APOB	4401	P04114
KVGYIEKLVILEIGQ	IGSF10	2416	Q6WRI0
KIDYGNKILELDLIV	DOCK2	151	Q92608
DVYKLLVQLKVVEDG	CTNNA1	146	P35221
NKEKEEELVEYLPQL	CCDC175	551	P0C221
TEGLKEANDIVLYLK	DNAH17	276	Q9UFH2
YEILLKDKTVLGSIN	CHD2	596	O14647
LKKYEGEIRQLEEAL	CGNL1	866	Q0VF96
VIAKEGQNLKELYLV	FBXL17	586	Q9UF56
LGEIITKYVYELLEK	FAM172A	101	Q8WUF8
DELELVKYKIISGNE	FAT3	606	Q8TDW7
NKGIYKAISELDILL	IL26	146	Q9NPH9
KKIVLLKGLEVINDY	PYHIN1	6	Q6K0P9
SKYAELLAIIEELGK	CDK2AP1	61	O14519
QVLKELLGQGIDYEK	COMMD4	36	Q9H0A8
LSVKEIYNEKELLQG	EIF3E	26	P60228
IYNEKELLQGKLDLL	EIF3E	31	P60228
TQEDLEYKLKGLIDL	IFRD1	76	O00458
ELQELYLKGNELKTL	GP1BA	141	P07359
KNIVLLKGLEVINDY	IFI16	6	Q16666
NGYIKVLLALKLQDE	IFIT1	216	P09914
VGLYFIKILELEEKQ	ITGA4	681	P13612
LLKEKLQEIYLQAEE	CXorf38	246	Q8TB03
ITVLALAEKLKENYI	HEATR1	2086	Q9H583
LAEKLKENYIVLLPE	HEATR1	2091	Q9H583
LYINVKLKAAEEIGI	MTHFD1	51	P11586
QGVKLYIKNLDDTID	PABPC4L	291	P0CB38
IVAKDLQDEKILYPE	OVGP1	66	Q12889
KEGLSLIYEQLKNII	UPF2	281	Q9HAU5
NINLLGKVELLDYLD	HSF2	351	Q03933
KLDQLQLEGLKYIER	PNPLA8	726	Q9NP80
KILVDYDEKGYLLQI	HPD	321	P32754
EKSRLDQELKLIGEY	RPS9	21	P46781
KVQVELTVLDYDKLG	SYT5	321	O00445
LTVLDYDKLGKNEAI	SYT5	326	O00445
VYLKEILKEIGVQNV	GTF2F2	211	P13984
ILGVLKRDEYLKKVE	SYTL5	21	Q8TDW5
LIIALGIQLDYEKIK	SQOR	141	Q9Y6N5
ILYEDLKENLAAGIK	SULT6B1	201	Q6IMI4
VLIIGELLKQADLYI	CCT6B	96	Q92526
VGLLLEYEAQKLSLV	SPRYD4	151	Q8WW59
VKQEAIKLLLVGDVY	SYNJ2	476	O15056
QYLGLALDVDRIKKD	NBPF8	706	Q3BBV2
YLGLALDVDRIKKDQ	NBPF9	911	P0DPF3
QYLGLALDVDRIKKD	NBPF10	741	Q6P3W6
EQYLGLALDVDRIKK	NBPF10	1716	Q6P3W6
QYLGLALDVDRIKKD	NBPF10	1961	Q6P3W6
YLGLALDVDRIKKDQ	NBPF10	2206	Q6P3W6
EQYLGLALDVDRIKK	NBPF10	2936	Q6P3W6
QYLGLALDVDRIKKD	NBPF10	3181	Q6P3W6
YLGLALDVDRIKKDQ	NBPF10	3426	Q6P3W6
LEEQYLGLALDVDKI	NBPF10	3666	Q6P3W6
QYLGLALDVDRIKKD	NBPF11	741	Q86T75
EQYLGLALDVDRIKK	NBPF12	1011	Q5TAG4
QYLGLALDVDRIKKD	NBPF12	1256	Q5TAG4
QYLGLALDVDRIKKD	NBPF14	401	Q5TI25
YLGLALDVDRIKKDQ	NBPF14	721	Q5TI25
YLGLALDVDRIKKDQ	NBPF15	471	Q8N660
YLGLALDVDRIKKDQ	NBPF19	471	A0A087WUL8
EQYLGLALDVDRIKK	NBPF19	1201	A0A087WUL8
QYLGLALDVDRIKKD	NBPF19	1446	A0A087WUL8
YLGLALDVDRIKKDQ	NBPF19	1691	A0A087WUL8
EQYLGLALDVDRIKK	NBPF19	2421	A0A087WUL8
QYLGLALDVDRIKKD	NBPF19	2666	A0A087WUL8
YLGLALDVDRIKKDQ	NBPF19	2911	A0A087WUL8
EQYLGLALDVDRIKK	NBPF19	3641	A0A087WUL8
QYLGLALDVDRIKKD	NBPF26	701	B4DH59
PKVAQYLLDKDLIID	RASGRF2	1206	O14827
YQKPLEELEVLKEAA	LAMA1	1736	P25391
LKALIENADAVYEKI	PLCL2	1011	Q9UPR0
VLLEIQKELLDYKGV	PSAT1	21	Q9Y617
LLKVYELLGGEEDIV	FGD1	571	P98174
LIEKVLDKVVQYLAE	SGSM2	136	O43147
EKYKLLVEGDNLRAV	POLR3A	1221	O14802
DLKGIQDKLDYITAL	SLC3A1	141	Q07837
VELEIKDKLLNYAGE	NUDT12	201	Q9BQG2
EIQLELYEVKFEILK	WHAMM	391	Q8TF30
LKLDNLLLDTEGYVK	PKN1	741	Q16512
VLVYDKLNVKISDLG	ROR2	621	Q01974
EGIDTILKLYLVSKN	HERC2P3	396	Q9BVR0
KQYGDKIIEELQDLG	OS9	266	Q13438
YKEVLEQVSKLAGVL	ACSS3	146	Q9H6R3
ERGKEITELLYKLIQ	CCDC54	161	Q8NEL0
ILDLEEEIYKQGKRK	CFAP210	121	Q0VFZ6
DVKSLLLEAYVKGQQ	CNOT1	1216	A5YKK6
DLILEKQPAYVKELE	VPS50	106	Q96JG6
LQILKEKEGIEYILL	UBE2Q2	256	Q8WVN8
VKLGVDTIAKYLDNI	UBXN6	171	Q9BZV1
LEQDLAYLQELKEKV	GGCX	611	P38435
NIEEIDEIPLVIKYK	WDR88	391	Q6ZMY6
KAKLNVEPDYLEVLE	SLITRK5	936	O94991
VYIAELEKIGIIVKA	SMC1B	116	Q8NDV3
QSLEKLLKDAIVYGQ	SPTLC2	286	O15270
KEIDEVGDLLQLKYS	SPTLC2	526	O15270
LKKVLGEKETLLYEN	SYCP1	436	Q15431
LNVYEIKVNKLELEL	SYCP1	636	Q15431
IKLEYARLVKLAQED	USP25	781	Q9UHP3
EYSEELEKLGILIKA	SMC1A	116	Q14683
ILLYKGDKDHIAVEL	SLIT2	1196	O94813
KIGLQVKELGADYID	SMCO2	136	A6NFE2
EAGLLNYLLEEILDK	PHF11	226	Q9UIL8
LDEKPKLQVELEQEY	PLCB1	1136	Q9NQ66
TALYDVLGIELKQQK	ARHGAP18	296	Q8N392
ILQDGKLDLEKEYQA	ZC3H12B	96	Q5HYM0
VYEKGKDLVVLELAT	VILL	256	O15195
ATNIDLKLKDYGVDL	PMS2	51	P54278
LKLKDYGVDLIEVSD	PMS2	56	P54278
DIYETVISLGLKLKN	ZNF75D	266	P51815
IKAKNDYPELAEIAL	ZBED9	1251	Q6R2W3
ELGEKLKKLIEQYAL	TXLNG	271	Q9NUQ3
KVLGILKKNVLYVDV	TUT4	431	Q5TAX3
LIGLEKFIQKEYDEK	TUT4	976	Q5TAX3
EILVKFIDVGGYKLL	PPP1R10	61	Q96QC0
EDLLLKYKQIQLELE	ZFC3H1	226	O60293
YEVEDLKLLAKIQAL	TBC1D2	571	Q9BYX2
KVLLLHLEEGKDLEY	MYO5A	36	Q9Y4I1
AIEGAKIEQYLLEKS	MYO7A	226	Q13402
LAEDVKLQLYKLLEI	NFKB1	811	P19838