Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein serine/threonine kinase activity	SMG1 NEK7 HIPK2 NEK9 HIPK3 PTK2B MTOR IRAK4 LTBP1 STKLD1 ULK2	3.28e-05	446	109	11	GO:0004674
GeneOntologyMolecularFunction	protein kinase activity	SMG1 NEK7 HIPK2 NEK9 HIPK3 PTK2B MTOR IRAK4 LTBP1 FGR STKLD1 ULK2	1.07e-04	600	109	12	GO:0004672
GeneOntologyMolecularFunction	regulatory region RNA binding	MBNL1 DHX9	2.92e-04	5	109	2	GO:0001069
GeneOntologyMolecularFunction	molecular adaptor activity	PAG1 OFD1 MID2 SYNE1 PHF24 HIPK2 JADE1 MED1 LDB2 STRIP1 DHX9 HIPK3 AP4E1 ZNF451 ROPN1B LTBP1 CSTPP1 NPAT	3.79e-04	1356	109	18	GO:0060090
GeneOntologyMolecularFunction	phosphotransferase activity, alcohol group as acceptor	SMG1 NEK7 HIPK2 NEK9 HIPK3 PTK2B MTOR IRAK4 LTBP1 FGR STKLD1 ULK2	4.92e-04	709	109	12	GO:0016773
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	PAG1 MID2 SYNE1 PHF24 HIPK2 JADE1 MED1 LDB2 STRIP1 DHX9 HIPK3 AP4E1 ZNF451 ROPN1B CSTPP1 NPAT	5.48e-04	1160	109	16	GO:0030674
GeneOntologyMolecularFunction	protein serine kinase activity	SMG1 NEK7 HIPK2 NEK9 HIPK3 MTOR IRAK4 ULK2	8.52e-04	363	109	8	GO:0106310
GeneOntologyMolecularFunction	kinase activity	SMG1 NEK7 HIPK2 NEK9 HIPK3 PTK2B MTOR IRAK4 LTBP1 FGR STKLD1 ULK2	9.47e-04	764	109	12	GO:0016301
GeneOntologyMolecularFunction	transcription coregulator activity	MID2 PHF24 HIPK2 JADE1 MED1 LDB2 DHX9 HIPK3 ZNF451 NPAT	1.01e-03	562	109	10	GO:0003712
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH1 SPTBN5 HTT	1.07e-03	37	109	3	GO:0045505
GeneOntologyBiologicalProcess	mesenchyme migration	ACTA1 ACTA2 ACTC1 ACTG2	3.81e-09	5	110	4	GO:0090131
GeneOntologyBiologicalProcess	mesenchyme morphogenesis	ACTA1 ACTA2 ACTC1 ACTG2 HTT	2.52e-05	65	110	5	GO:0072132
GeneOntologyCellularComponent	PML body	HIPK2 THAP1 HIPK3 MTOR ZNF451 USP7	4.96e-05	125	109	6	GO:0016605
GeneOntologyCellularComponent	nuclear body	SDE2 HIPK2 COP1 JADE1 THAP1 DHX9 HIPK3 MTOR CTR9 ZNF451 USP7 SGO2 PLA2G6 NPAT	2.52e-04	903	109	14	GO:0016604
Domain	ACTINS_1	ACTA1 ACTA2 ACTC1 ACTG2	6.74e-08	8	106	4	PS00406
Domain	Actin_CS	ACTA1 ACTA2 ACTC1 ACTG2	1.69e-06	16	106	4	IPR004001
Domain	ACTINS_2	ACTA1 ACTA2 ACTC1 ACTG2	2.20e-06	17	106	4	PS00432
Domain	Actin/actin-like_CS	ACTA1 ACTA2 ACTC1 ACTG2	2.82e-06	18	106	4	IPR020902
Domain	ACTINS_ACT_LIKE	ACTA1 ACTA2 ACTC1 ACTG2	3.56e-06	19	106	4	PS01132
Domain	Actin	ACTA1 ACTA2 ACTC1 ACTG2	2.74e-05	31	106	4	IPR004000
Domain	Actin	ACTA1 ACTA2 ACTC1 ACTG2	2.74e-05	31	106	4	PF00022
Domain	ACTIN	ACTA1 ACTA2 ACTC1 ACTG2	2.74e-05	31	106	4	SM00268
Domain	Kinase-like_dom	SMG1 NEK7 HIPK2 NEK9 HIPK3 PTK2B MTOR IRAK4 FGR STKLD1 ULK2	2.56e-04	542	106	11	IPR011009
Domain	FATC	SMG1 MTOR	3.16e-04	5	106	2	PF02260
Domain	FAT	SMG1 MTOR	4.72e-04	6	106	2	PS51189
Domain	FATC	SMG1 MTOR	4.72e-04	6	106	2	PS51190
Domain	FATC_dom	SMG1 MTOR	4.72e-04	6	106	2	IPR003152
Domain	PIK_FAT	SMG1 MTOR	4.72e-04	6	106	2	IPR014009
Domain	FATC	SMG1 MTOR	4.72e-04	6	106	2	SM01343
Domain	LisH	OFD1 WDR26 NPAT	5.25e-04	28	106	3	IPR006594
Domain	LisH	OFD1 WDR26 NPAT	5.25e-04	28	106	3	SM00667
Domain	LISH	OFD1 WDR26 NPAT	5.25e-04	28	106	3	PS50896
Domain	HEAT_REPEAT	SMG1 ODAD2 MTOR HTT	6.74e-04	70	106	4	PS50077
Domain	PROTEIN_KINASE_ATP	NEK7 HIPK2 NEK9 HIPK3 PTK2B IRAK4 FGR STKLD1 ULK2	1.21e-03	459	106	9	PS00107
Domain	Prot_kinase_dom	NEK7 HIPK2 NEK9 HIPK3 PTK2B IRAK4 FGR STKLD1 ULK2	1.87e-03	489	106	9	IPR000719
Domain	PROTEIN_KINASE_DOM	NEK7 HIPK2 NEK9 HIPK3 PTK2B IRAK4 FGR STKLD1 ULK2	1.97e-03	493	106	9	PS50011
Domain	PI3/4_kinase_CS	SMG1 MTOR	3.19e-03	15	106	2	IPR018936
Domain	ARM-type_fold	SMG1 ODAD2 NCDN AP4E1 MTOR STKLD1 HTT	3.21e-03	339	106	7	IPR016024
Domain	-	SMG1 MTOR	3.64e-03	16	106	2	1.10.1070.11
Domain	PI3Kc	SMG1 MTOR	3.64e-03	16	106	2	SM00146
Domain	FN3	FN1 LRRN1 MID2 PTPRM IL4R	4.09e-03	185	106	5	SM00060
Domain	HEAT	ODAD2 MTOR HTT	4.37e-03	58	106	3	IPR000357
Domain	ARM-like	SMG1 ODAD2 AP4E1 MTOR STKLD1 HTT	4.41e-03	270	106	6	IPR011989
Domain	PI3_PI4_kinase	SMG1 MTOR	4.60e-03	18	106	2	PF00454
Domain	PI3_4_KINASE_1	SMG1 MTOR	4.60e-03	18	106	2	PS00915
Domain	PI3_4_KINASE_2	SMG1 MTOR	4.60e-03	18	106	2	PS00916
Domain	PI3/4_kinase_cat_dom	SMG1 MTOR	4.60e-03	18	106	2	IPR000403
Domain	PI3_4_KINASE_3	SMG1 MTOR	4.60e-03	18	106	2	PS50290
Domain	FN3	FN1 LRRN1 MID2 PTPRM IL4R	5.55e-03	199	106	5	PS50853
Pathway	WP_MECHANOREGULATION_AND_PATHOLOGY_OF_YAPTAZ_VIA_HIPPO_AND_NONHIPPO_MECHANISMS	ACTA1 ACTA2 ACTC1 ACTG2 ITGB8	6.20e-06	47	79	5	M39829
Pubmed	Actin associates with the nucleocapsid domain of the human immunodeficiency virus Gag polyprotein.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	9971772
Pubmed	Interaction of the human immunodeficiency virus type 1 nucleocapsid with actin.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	10074138
Pubmed	Virus assembly and plasma membrane domains: which came first?	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	22989508
Pubmed	HIV-1 protease cleaves actin during acute infection of human T-lymphocytes.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	1540415
Pubmed	HIV type 1 Gag and nucleocapsid proteins: cytoskeletal localization and effects on cell motility.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	11709093
Pubmed	Tagging the human immunodeficiency virus gag protein with green fluorescent protein. Minimal evidence for colocalisation with actin.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	10049817
Pubmed	Human immunodeficiency virus nucleocapsid protein polymorphisms modulate the infectivity of RNA packaging mutants.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	12009869
Pubmed	HIV-1 Tat protein variants: critical role for the cysteine region in synaptodendritic injury.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	23811015
Pubmed	Retroviral assembly and budding occur through an actin-driven mechanism.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	19883584
Pubmed	Dynamic imaging of cell-free and cell-associated viral capture in mature dendritic cells.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	21917091
Pubmed	HIV-1 Gag protein associates with F-actin present in microfilaments.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	8661406
Pubmed	A protein ballet around the viral genome orchestrated by HIV-1 reverse transcriptase leads to an architectural switch: from nucleocapsid-condensed RNA to Vpr-bridged DNA.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	23017337
Pubmed	Synaptodendritic recovery following HIV Tat exposure: neurorestoration by phytoestrogens.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	23875777
Pubmed	Establishment of a functional human immunodeficiency virus type 1 (HIV-1) reverse transcription complex involves the cytoskeleton.	ACTA1 ACTA2 ACTC1 ACTG2	1.52e-09	6	112	4	9841925
Pubmed	The cleavage of host cell proteins by HIV-1 protease.	FN1 ACTA1 ACTA2 ACTC1 ACTG2	1.90e-09	17	112	5	8997639
Pubmed	The PDZ-adaptor protein syntenin-1 regulates HIV-1 entry.	ACTA1 ACTA2 ACTC1 ACTG2	3.54e-09	7	112	4	22535526
Pubmed	Selective targeting of ITK blocks multiple steps of HIV replication.	ACTA1 ACTA2 ACTC1 ACTG2	3.54e-09	7	112	4	18443296
Pubmed	The trinity of the cortical actin in the initiation of HIV-1 infection.	ACTA1 ACTA2 ACTC1 ACTG2	3.54e-09	7	112	4	22640593
Pubmed	HIV-1 replication from after cell entry to the nuclear periphery.	ACTA1 ACTA2 ACTC1 ACTG2	3.54e-09	7	112	4	17504171
Pubmed	siRNA and pharmacological inhibition of endocytic pathways to characterize the differential role of macropinocytosis and the actin cytoskeleton on cellular uptake of dextran and cationic cell penetrating peptides octaarginine (R8) and HIV-Tat.	ACTA1 ACTA2 ACTC1 ACTG2	3.54e-09	7	112	4	22465675
Pubmed	Human immunodeficiency virus type 1 Tat regulates endothelial cell actin cytoskeletal dynamics through PAK1 activation and oxidant production.	ACTA1 ACTA2 ACTC1 ACTG2	7.06e-09	8	112	4	14694110
Pubmed	Lentiviral Nef proteins utilize PAK2-mediated deregulation of cofilin as a general strategy to interfere with actin remodeling.	ACTA1 ACTA2 ACTC1 ACTG2	7.06e-09	8	112	4	20147394
Pubmed	Interleukin 2-inducible T cell kinase (ITK) facilitates efficient egress of HIV-1 by coordinating Gag distribution and actin organization.	ACTA1 ACTA2 ACTC1 ACTG2	7.06e-09	8	112	4	23260110
Pubmed	Functional interaction between the cytoplasmic leucine-zipper domain of HIV-1 gp41 and p115-RhoGEF.	ACTA1 ACTA2 ACTC1 ACTG2	1.27e-08	9	112	4	10556093
Pubmed	Cytoskeletal proteins inside human immunodeficiency virus type 1 virions.	ACTA1 ACTA2 ACTC1 ACTG2	1.27e-08	9	112	4	8892894
Pubmed	HIV envelope-CXCR4 signaling activates cofilin to overcome cortical actin restriction in resting CD4 T cells.	ACTA1 ACTA2 ACTC1 ACTG2	1.27e-08	9	112	4	18775311
Pubmed	Actin, troponin C, Alzheimer amyloid precursor protein and pro-interleukin 1 beta as substrates of the protease from human immunodeficiency virus.	ACTA1 ACTA2 ACTC1 ACTG2	2.11e-08	10	112	4	1907279
Pubmed	Non-viral cellular substrates for human immunodeficiency virus type 1 protease.	ACTA1 ACTA2 ACTC1 ACTG2	2.11e-08	10	112	4	1991513
Pubmed	Gelsolin activity controls efficient early HIV-1 infection.	ACTA1 ACTA2 ACTC1 ACTG2	2.11e-08	10	112	4	23575248
Pubmed	Reexamination of chromosomal loci of human muscle actin genes by fluorescence in situ hybridization.	ACTA1 ACTA2 ACTC1	3.25e-08	3	112	3	7780165
Pubmed	CAP2 deficiency delays myofibril actin cytoskeleton differentiation and disturbs skeletal muscle architecture and function.	ACTA1 ACTA2 ACTC1 ACTG2	3.30e-08	11	112	4	30962377
Pubmed	N-terminal Slit2 inhibits HIV-1 replication by regulating the actin cytoskeleton.	ACTA1 ACTA2 ACTC1 ACTG2	3.30e-08	11	112	4	23294842
Pubmed	Quantitative proteomic analysis of lentiviral vectors using 2-DE.	ACTA1 ACTA2 ACTC1 ACTG2	3.30e-08	11	112	4	19639585
Pubmed	HIV-1 Nef impairs heterotrimeric G-protein signaling by targeting Gα(i2) for degradation through ubiquitination.	ACTA1 ACTA2 ACTC1 ACTG2	4.94e-08	12	112	4	23071112
Pubmed	LIM kinase 1 - dependent cofilin 1 pathway and actin dynamics mediate nuclear retinoid receptor function in T lymphocytes.	ACTA1 ACTA2 ACTC1 ACTG2	9.95e-08	14	112	4	21923909
Pubmed	Regulating the functions of the HIV-1 matrix protein.	ACTA1 ACTA2 ACTC1 ACTG2	9.95e-08	14	112	4	17411366
Pubmed	Requirement for an intact T-cell actin and tubulin cytoskeleton for efficient assembly and spread of human immunodeficiency virus type 1.	ACTA1 ACTA2 ACTC1 ACTG2	2.35e-07	17	112	4	17360745
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	SGSM1 MAN2B2 LRRN1 MID2 MBNL1 PTDSS1 HIPK2 CHD2 NEK9 NCDN DNAH1 HIPK3 MALT1 PLA2G6 PBX1 DAGLA TRAPPC9 GOLGA4 HTT	2.82e-07	1489	112	19	28611215
Pubmed	USP7 negatively controls global DNA methylation by attenuating ubiquitinated histone-dependent DNMT1 recruitment.	H3C1 USP7 DNMT1	3.24e-07	5	112	3	32884836
Pubmed	Transcriptome of the inner circular smooth muscle of the developing mouse intestine: Evidence for regulation of visceral smooth muscle genes by the hedgehog target gene, cJun.	FN1 ZNF423 ACTA2 ACTC1 ACTG2 LTBP1 PBX1	3.75e-07	140	112	7	26930384
Pubmed	Myocardial Mycn is essential for mouse ventricular wall morphogenesis.	ACTA1 ACTA2 ACTC1 MTOR	5.85e-07	21	112	4	23063798
Pubmed	Modifications in the human T cell proteome induced by intracellular HIV-1 Tat protein expression.	ACTA1 ACTA2 ACTC1 ACTG2	7.13e-07	22	112	4	16526095
Pubmed	Essential and supporting host cell factors for HIV-1 budding.	ACTA1 ACTA2 ACTC1 ACTG2	8.61e-07	23	112	4	22004035
Pubmed	Mice lacking factor VII develop normally but suffer fatal perinatal bleeding.	ACTA1 ACTA2 ACTC1	1.13e-06	7	112	3	9384381
Pubmed	A Novel Mouse Model for Cilia-Associated Cardiovascular Anomalies with a High Penetrance of Total Anomalous Pulmonary Venous Return.	ACTA1 ACTA2 ACTC1	1.13e-06	7	112	3	30289203
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	ACTA1 ACTA2 ACTC1 ACTG2	1.44e-06	26	112	4	24742657
Pubmed	Fibulin-1 is required for morphogenesis of neural crest-derived structures.	FN1 ACTA1 ACTA2	1.80e-06	8	112	3	18538758
Pubmed	Reduced versican cleavage due to Adamts9 haploinsufficiency is associated with cardiac and aortic anomalies.	ACTA1 ACTA2 ACTC1	1.80e-06	8	112	3	20096780
Pubmed	Sox4-deficiency syndrome in mice is an animal model for common trunk.	FN1 ACTA2 ACTC1	1.80e-06	8	112	3	9815146
Pubmed	Extensive vasculogenesis, angiogenesis, and organogenesis precede lethality in mice lacking all alpha v integrins.	FN1 ACTA2 ACTG2	2.69e-06	9	112	3	9827803
Pubmed	Modulation of cardiac growth and development by HOP, an unusual homeodomain protein.	ACTA1 ACTA2 ACTC1	2.69e-06	9	112	3	12297046
Pubmed	The tissue-specific lncRNA Fendrr is an essential regulator of heart and body wall development in the mouse.	ACTA1 ACTA2 ACTC1 ACTG2	3.42e-06	32	112	4	23369715
Pubmed	Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.	ACTA1 ACTA2 ACTC1	3.84e-06	10	112	3	21749862
Pubmed	FRS2α-mediated FGF signals suppress premature differentiation of cardiac stem cells through regulating autophagy activity.	ACTA1 ACTA2 ACTC1	5.26e-06	11	112	3	22207710
Pubmed	SEMA6D regulates perinatal cardiomyocyte proliferation and maturation in mice.	ACTA1 ACTA2 ACTC1	7.00e-06	12	112	3	31042497
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	POGK SYNE1 ZNF423 PHF24 ARHGEF12 NCDN STRIP1 ZNF451 ULK2	7.16e-06	407	112	9	12693553
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	SMG1 PAG1 NEK7 HIPK2 CHD2 WDR26 NEK9 HIPK3 PTK2B CTR9 IRAK4 USP7 G6PD	7.73e-06	910	112	13	36736316
Pubmed	Pygo1 regulates pathological cardiac hypertrophy via a β-catenin-dependent mechanism.	FN1 ACTA1 ACTA2	9.08e-06	13	112	3	33635162
Pubmed	Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice.	ACTA1 ACTA2 ACTC1	9.08e-06	13	112	3	18400219
Pubmed	Investigation of changes in skeletal muscle alpha-actin expression in normal and pathological human and mouse hearts.	ACTA1 ACTC1	1.03e-05	2	112	2	20706863
Pubmed	A 5' duplication of the alpha-cardiac actin gene in BALB/c mice is associated with abnormal levels of alpha-cardiac and alpha-skeletal actin mRNAs in adult cardiac tissue.	ACTA1 ACTC1	1.03e-05	2	112	2	3023046
Pubmed	Kidney-specific inactivation of Ofd1 leads to renal cystic disease associated with upregulation of the mTOR pathway.	OFD1 MTOR	1.03e-05	2	112	2	20444807
Pubmed	PTPRM methylation induced by FN1 promotes the development of glioblastoma by activating STAT3 signalling.	FN1 PTPRM	1.03e-05	2	112	2	34225581
Pubmed	Inhibition of HIPK3 by AST487 Ameliorates Mutant HTT-Induced Neurotoxicity and Apoptosis via Enhanced Autophagy.	HIPK3 HTT	1.03e-05	2	112	2	34741261
Pubmed	Transcripts of alpha-cardiac and alpha-skeletal actins are early markers for myogenesis in the mouse embryo.	ACTA1 ACTC1	1.03e-05	2	112	2	3075543
Pubmed	Rescue of cardiac alpha-actin-deficient mice by enteric smooth muscle gamma-actin.	ACTC1 ACTG2	1.03e-05	2	112	2	9114002
Pubmed	Insights into Conformational Dynamics and Allostery in DNMT1-H3Ub/USP7 Interactions.	USP7 DNMT1	1.03e-05	2	112	2	34500587
Pubmed	Expanding the genetic and phenotypic spectrum of TRAPPC9 and MID2-related neurodevelopmental disabilities: report of two novel mutations, 3D-modelling, and molecular docking studies.	MID2 TRAPPC9	1.03e-05	2	112	2	38467738
Pubmed	Molecular mechanism for USP7-mediated DNMT1 stabilization by acetylation.	USP7 DNMT1	1.03e-05	2	112	2	25960197
Pubmed	Rescue of skeletal muscle alpha-actin-null mice by cardiac (fetal) alpha-actin.	ACTA1 ACTC1	1.03e-05	2	112	2	19468071
Pubmed	An autoinhibitory tyrosine motif in the cell-cycle-regulated Nek7 kinase is released through binding of Nek9.	NEK7 NEK9	1.03e-05	2	112	2	19941817
Pubmed	Mechanistic basis of Nek7 activation through Nek9 binding and induced dimerization.	NEK7 NEK9	1.03e-05	2	112	2	26522158
Pubmed	Pyk2 modulates hippocampal excitatory synapses and contributes to cognitive deficits in a Huntington's disease model.	PTK2B HTT	1.03e-05	2	112	2	28555636
Pubmed	Characterization of the motor activity of mammalian myosin VIIA.	MYO7A ACTA1	1.03e-05	2	112	2	12466270
Pubmed	alpha-Actin proteins and gene transcripts are colocalized in embryonic mouse muscle.	ACTA1 ACTC1	1.03e-05	2	112	2	1893870
Pubmed	Deubiquitinase USP7 contributes to the pathogenicity of spinal and bulbar muscular atrophy.	USP7 HTT	1.03e-05	2	112	2	33170804
Pubmed	Latent transforming growth factor-beta 1 and its binding protein are components of extracellular matrix microfibrils.	FN1 LTBP1	1.03e-05	2	112	2	8756760
Pubmed	Spatiotemporal expression of otogelin in the developing and adult mouse inner ear.	MYO7A OTOG	1.03e-05	2	112	2	11506947
Pubmed	Independent functions of DNMT1 and USP7 at replication foci.	USP7 DNMT1	1.03e-05	2	112	2	29482658
Pubmed	Muscle specific expression of Cre recombinase under two actin promoters in transgenic mice.	ACTA2 ACTC1	1.03e-05	2	112	2	10686609
Pubmed	Increased myocardial dysfunction after ischemia-reperfusion in mice lacking glucose-6-phosphate dehydrogenase.	FGR G6PD	1.03e-05	2	112	2	14757696
Pubmed	A developmental study of the abnormal expression of alpha-cardiac and alpha-skeletal actins in the striated muscle of a mutant mouse.	ACTA1 ACTC1	1.03e-05	2	112	2	2731651
Pubmed	A fetal skeletal muscle actin mRNA in the mouse and its identity with cardiac actin mRNA.	ACTA1 ACTC1	1.03e-05	2	112	2	6897014
Pubmed	Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.	STARD8 FN1 MBNL1 HIPK2 CHD2 JADE1 NCDN RHOH CTR9 IRAK4 IL17RD ULK2 CSTPP1 NPAT	1.06e-05	1084	112	14	11544199
Pubmed	A gene expression resource generated by genome-wide lacZ profiling in the mouse.	STARD8 VXN AP4E1 SGO2	1.25e-05	44	112	4	26398943
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	OFD1 MYO7A JADE1 KIAA2013 ITPR3 MTOR USP7 PCNX1 PLA2G6 IL17RD ULK2 IL4R TRAPPC9 HTT	1.31e-05	1105	112	14	35748872
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	CACUL1 MID2 NEK7 ARHGEF12 CHD2 AP4E1 CD3D ZNF451 IL17RD GOLGA4 CSTPP1	1.40e-05	686	112	11	29987050
Pubmed	Severe protein aggregate myopathy in a knockout mouse model points to an essential role of cofilin2 in sarcomeric actin exchange and muscle maintenance.	ACTA1 ACTA2 ACTC1	1.44e-05	15	112	3	24598388
Pubmed	Shotgun proteomics reveals specific modulated protein patterns in tears of patients with primary open angle glaucoma naïve to therapy.	ACTA1 ACTA2 ACTC1 ACTG2 KRT87P	1.53e-05	96	112	5	23580065
Pubmed	Extraocular muscle morphogenesis and gene expression are regulated by Pitx2 gene dose.	ACTA1 ACTA2 ACTC1	1.77e-05	16	112	3	16638982
Pubmed	Serum response factor is essential for mesoderm formation during mouse embryogenesis.	ACTA1 ACTA2 ACTC1	1.77e-05	16	112	3	9799237
Pubmed	A cardiomyocyte-specific Wdr1 knockout demonstrates essential functional roles for actin disassembly during myocardial growth and maintenance in mice.	ACTA1 ACTA2 ACTC1	2.56e-05	18	112	3	24840128
Pubmed	Conditional mutagenesis of the murine serum response factor gene blocks cardiogenesis and the transcription of downstream gene targets.	ACTA1 ACTA2 ACTC1	2.56e-05	18	112	3	15929941
Pubmed	Myocardial-specific ablation of Jumonji and AT-rich interaction domain-containing 2 (Jarid2) leads to dilated cardiomyopathy in mice.	ACTA1 ACTA2 ACTC1	3.03e-05	19	112	3	30700554
Pubmed	Heart-specific ablation of Prkar1a causes failure of heart development and myxomagenesis.	ACTA1 ACTA2 ACTC1	3.03e-05	19	112	3	18316483
Pubmed	Nuclear retention of full-length HTT RNA is mediated by splicing factors MBNL1 and U2AF65.	MBNL1 HTT	3.08e-05	3	112	2	26218986
Pubmed	Urinary mRNA markers of epithelial-mesenchymal transition correlate with progression of diabetic nephropathy.	FN1 ACTA1	3.08e-05	3	112	2	21824169
Pubmed	Suppression of MAPK11 or HIPK3 reduces mutant Huntingtin levels in Huntington's disease models.	HIPK3 HTT	3.08e-05	3	112	2	29151587
Pubmed	Actin and myosin genes are transcriptionally regulated during mouse skeletal muscle development.	ACTA1 ACTC1	3.08e-05	3	112	2	1728592
Pubmed	Molecular analysis of smooth muscle development in the mouse.	ACTA2 ACTG2	3.08e-05	3	112	2	8573719
GeneFamily	Actins	ACTA1 ACTA2 ACTC1 ACTG2	3.07e-09	6	70	4	929
GeneFamily	Trafficking protein particle complex	TRAPPC11 TRAPPC9	1.30e-03	14	70	2	772
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	SMG1 PAG1 GPR65 OFD1 MYO7A SYNE1 MBNL1 PTDSS1 NEK7 CHD2 JADE1 MED1 WDR26 NEK9 DHX9 PTK2B MALT1 RHOH CD3D IRAK4 PCNX1 DNMT1 NPAT	4.85e-08	1492	110	23	M40023
Coexpression	LAKE_ADULT_KIDNEY_C22_ENDOTHELIAL_CELLS_GLOMERULAR_CAPILLARIES	SYNE1 MBNL1 HIPK2 ARHGEF12 LDB2 PTPRM PBX1	1.86e-06	137	110	7	M39241
Coexpression	GSE32255_UNSTIM_VS_4H_LPS_STIM_DC_UP	MID2 NEK7 ITGB8 RHOH PLA2G6 ALAS1 CSTPP1	1.39e-05	186	110	7	M8914
Coexpression	GSE17974_IL4_AND_ANTI_IL12_VS_UNTREATED_4H_ACT_CD4_TCELL_UP	MYO7A SYNE1 DENND10 MTOR IRAK4 IL4R HTT	1.83e-05	194	110	7	M4213
Coexpression	GSE360_HIGH_VS_LOW_DOSE_B_MALAYI_DC_UP	GPR65 ACTA2 ACTC1 MED1 AP4E1 USP7 LTBP1	2.08e-05	198	110	7	M5222
Coexpression	BRCA1_DN.V1_UP	ZNF423 LDB2 RHOH CD3D ROPN1B DAGLA	2.12e-05	133	110	6	M2748
Coexpression	GSE3691_CONVENTIONAL_VS_PLASMACYTOID_DC_SPLEEN_UP	HIPK2 NDRG3 WDR26 ITPR3 HIPK3 ULK2 IL4R	2.22e-05	200	110	7	M6369
Coexpression	GSE13411_SWITCHED_MEMORY_BCELL_VS_PLASMA_CELL_UP	TRAPPC11 MAN2B2 JADE1 NDRG3 PTK2B RHOH PCNX1	2.22e-05	200	110	7	M3251
Coexpression	STK33_SKM_UP	GPR65 ACTA2 THAP1 ITGB8 H3C1 PTPRM FGR PID1	2.39e-05	279	110	8	M2857
Coexpression	DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_DN	GPR65 DENND10P1 SYNE1 MALT1 CD3D PTPRM CTR9 NPAT	6.72e-05	323	110	8	M12570
Coexpression	YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN	FN1 ACTA1 G6PD	7.78e-05	20	110	3	M4435
Coexpression	YAO_HOXA10_TARGETS_VIA_PROGESTERONE_DN	FN1 ACTA1 G6PD	7.78e-05	20	110	3	MM637
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_J_emap-30374_k-means-cluster#4_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	8.68e-06	26	108	4	gudmap_developingLowerUrinaryTract_P1_bladder_J_100_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#3_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2	1.18e-05	28	108	4	gudmap_developingLowerUrinaryTract_P1_bladder_B_100_k3
CoexpressionAtlas	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1	MAN2B2 MID2 MYO7A SYNE1 MBNL1 PTDSS1 NEK7 HIPK2 CHML GLMP PTPRM IRAK4 PCNX1 LTBP1 PBX1	2.61e-05	850	108	15	gudmap_RNAseq_p2_Glomerlular Endothelial_2500_K1
CoexpressionAtlas	DevelopingKidney_e14.5 whole kidney - Wnt4 KO_emap-6674_top-relative-expression-ranked_500	SMG1 LRRN1 ACTC1 MED1 LDB2 ZFHX4 ZNF451 ADAMTS20 DIXDC1 ULK2	2.92e-05	388	108	10	gudmap_developingKidney_e14.5 whole kidney - Wnt4 KO_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#3_top-relative-expression-ranked_100	ACTA2 ACTC1 ACTG2	5.57e-05	15	108	3	gudmap_developingLowerUrinaryTract_P1_ureter_100_k3
CoexpressionAtlas	DevelopingLowerUrinaryTract_e15.5_ureteral tissue_emap-8234_k-means-cluster#5_top-relative-expression-ranked_200	ACTA1 ACTC1 ACTG2	8.26e-05	17	108	3	gudmap_developingLowerUrinaryTract_e15.5_ureteral tissue_200_k5
CoexpressionAtlas	DevelopingLowerUrinaryTract_P2_bladder detrusor (LCM)_emap-30376_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTC1 ACTG2 THRSP	8.69e-05	88	108	5	gudmap_developingLowerUrinaryTract_P2_bladder detrusor (LCM)_100
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_k-means-cluster#4_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2	1.04e-04	48	108	4	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_100	ACTA1 ACTA2 ACTG2	1.17e-04	19	108	3	gudmap_developingLowerUrinaryTract_adult_bladder_100_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_200	ACTA1 ACTA2 ACTC1 ACTG2	1.22e-04	50	108	4	gudmap_developingLowerUrinaryTract_P1_bladder_B_200_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_adult_bladder_emap-29457_k-means-cluster#4_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2 THRSP	2.18e-04	107	108	5	gudmap_developingLowerUrinaryTract_adult_bladder_500_k4
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_1000	SMG1 PAG1 POGK ACTA1 ACTA2 HIPK2 ACTC1 ACTG2 WDR26 HIPK3 ZFHX4 ADAMTS20 DIXDC1	2.28e-04	806	108	13	gudmap_developingLowerUrinaryTract_e14.5_ urethra_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urethra_emap-30892_top-relative-expression-ranked_500	PAG1 ACTA1 ACTA2 HIPK2 ACTC1 ACTG2 HIPK3 ZFHX4 DIXDC1	2.35e-04	407	108	9	gudmap_developingLowerUrinaryTract_e14.5_ urethra_500
CoexpressionAtlas	DevelopingLowerUrinaryTract_e14.5_ urogenital sinus_emap-5517_top-relative-expression-ranked_1000	SMG1 PAG1 LRRN1 ZNF423 HIPK2 MED1 WDR26 HIPK3 ZFHX4 USP7 ADAMTS20 LTBP1 TCFL5	2.64e-04	818	108	13	gudmap_developingLowerUrinaryTract_e14.5_ urogenital sinus_1000
CoexpressionAtlas	kidney_P3_CapMes_Crym_k-means-cluster#2_top-relative-expression-ranked_1000	MID2 HIPK2 ARHGEF12 PTPRM DAGLA	2.93e-04	114	108	5	gudmap_kidney_P3_CapMes_Crym_k2_1000
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_bladder_B_emap-30374_k-means-cluster#2_top-relative-expression-ranked_500	ACTA1 ACTA2 ACTC1 ACTG2 THRSP	3.05e-04	115	108	5	gudmap_developingLowerUrinaryTract_P1_bladder_B_500_k2
CoexpressionAtlas	DevelopingLowerUrinaryTract_P1_ureter_emap-30363_k-means-cluster#4_top-relative-expression-ranked_200	ACTA2 ACTC1 ACTG2	3.42e-04	27	108	3	gudmap_developingLowerUrinaryTract_P1_ureter_200_k4
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TCEA3 FN1 SYNE1 ACTA2 ACTG2 DIXDC1 LTBP1 PBX1	3.30e-08	199	109	8	e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCell	facs-Pancreas-Exocrine-24m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CENPL ACTA2 ITGB8 ZNF451 SGO2 KBTBD12 IL17RD	1.22e-07	157	109	7	370f44047ef438b8f1124c2c2761c150c0d8c57f
ToppCell	COVID_non-vent-Lymphocytic\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	SMG1 OFD1 SYNE1 MBNL1 CHD2 RHOH CD3D	5.67e-07	197	109	7	c672915f8c8c1e948d251f6eaf9f84a5600c1193
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-1_mon-Proliferating-Cycling_Progenitors\|1_mon / Sample Type, Dataset, Time_group, and Cell type.	TRAPPC11 PAG1 POGK HIPK2 JADE1 ZFHX4 LTBP1	6.06e-07	199	109	7	358c4b3037f59378db8916a2fbe9ed4830cf1449
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 RGS22 ACTA2 ACTG2 DIXDC1 LTBP1	6.27e-07	200	109	7	c5e051f1aac8dda376c342a9932785a23450e073
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1 LTBP1	6.27e-07	200	109	7	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1 LTBP1	6.27e-07	200	109	7	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TCEA3 FN1 SYNE1 ACTA2 ACTG2 DIXDC1 LTBP1	6.27e-07	200	109	7	c596a53c0b63c9deaac7d99fcbdd94ecfa96b86c
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 RGS22 ACTA2 ACTG2 DIXDC1 LTBP1	6.27e-07	200	109	7	8988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTG2 ZFHX4 DIXDC1 LTBP1	6.27e-07	200	109	7	08bf8c00eee6468215edb3611296bfc8784c4d56
ToppCell	COVID-19-kidney-Mito-rich_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	SYNE1 HIPK2 LDB2 PTPRM PBX1 OTOG	1.56e-06	145	109	6	afed661aef990edb8e7012ab67ace56443520c9f
ToppCell	10x5'-blood-Lymphocytic_T_CD4-T_CD4/CD8\|blood / Manually curated celltypes from each tissue	SMG1 PAG1 MBNL1 CHD2 RHOH PCNX1	2.96e-06	162	109	6	b4535bcb3f469bc139e73f1122f4070013e5a1de
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	SMG1 SYNE1 MBNL1 CHD2 PCNX1 CCDC144A	4.04e-06	171	109	6	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	3'-GW_trimst-1-LargeIntestine-Mesenchymal-myocytic-SMC_(PART1/CAPN3+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 SYNE1 ACTA2 ACTG2 ZFHX4 PBX1	5.09e-06	178	109	6	0fb36679cddc9ed8f4b5b34e174d5133c2ea1c76
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS22 ODAD2 DNAH1 ZFHX4 ADAMTS20 OTOG	6.16e-06	184	109	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS22 ODAD2 DNAH1 ZFHX4 ADAMTS20 OTOG	6.16e-06	184	109	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RGS22 ODAD2 DNAH1 ZFHX4 ADAMTS20 OTOG	6.16e-06	184	109	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCEA3 SYNE1 ACTA2 ACTG2 DIXDC1 PBX1	6.35e-06	185	109	6	e64e8c98dd88d91f6501d3fb10b60fd2f3c90af3
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_fibroblastic-mes_immature_COL13A1^pos_fibro2_(5)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	FN1 HIPK2 ACTG2 LDB2 LTBP1 PID1	6.55e-06	186	109	6	7def03dd856b765bd3f493288641981c4f7fd26e
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCEA3 LRRN1 SYNE1 RGS22 ACTA2 ACTG2	6.96e-06	188	109	6	3177b2c1723268d330d3e9f24f9e24492ace6286
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_ASM_(13)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	TCEA3 ACTA2 ACTC1 ACTG2 LTBP1 IL4R	6.96e-06	188	109	6	f54b063025d80de631382bf5326bc40aab7f7d00
ToppCell	LPS_only-Stromal_mesenchymal-Lung_smooth_muscle\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TCEA3 SYNE1 ACTA2 ACTC1 ACTG2 PBX1	7.62e-06	191	109	6	08042952431ca1a6fd7dfc13f36eb28643979598
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes-Fibromyocytes_L.2.3.2.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	7.62e-06	191	109	6	d35692c652977500a3c36aa26c347a072b71e441
ToppCell	3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-tracheobronchial_smooth_muscle_cell-Fibromyocytes\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	7.62e-06	191	109	6	2a107e9096eb58b81b3da61547904d85754f6b2f
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	PAG1 LRRN1 ACTA2 ITGB8 LTBP1 PBX1	7.85e-06	192	109	6	72881b280a415e65f87a80ca1369cbb0b722a0c4
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ZNF423 LDB2 PTPRM PBX1 IL4R	7.85e-06	192	109	6	c0e59e642b42c055cf73d029cf54d07d9b719359
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 ACTA2 LDB2 ZFHX4 LTBP1 PID1	8.09e-06	193	109	6	c8c21eee8c6c086dc2faf416669cd4a002870fbe
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 ACTA2 LDB2 ZFHX4 LTBP1 PID1	8.09e-06	193	109	6	5b602b1702283184bd3943c2a6f2290b7c37e407
ToppCell	wk_08-11-Hematologic-Meg-ery-Definitive_erythroblast\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SDE2 ARHGEF12 WDR26 PTK2B ZNF451 USP7	8.09e-06	193	109	6	be75abfdf5301cf33df8ee9ed92504d44fdf19a6
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ZNF423 LDB2 PTPRM PBX1 IL4R	8.09e-06	193	109	6	52e918884877b6659cdca0496390e440f73694a9
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ZNF423 LDB2 LTBP1 PBX1 PID1 DNMT1	8.58e-06	195	109	6	ff0aa455e9844a6d7ae57ff59fb6cea825cf1fc2
ToppCell	COVID_non-vent-Lymphocytic-T_cell\|COVID_non-vent / Disease condition, Lineage, Cell class and subclass	TCEA3 PAG1 MBNL1 CHD2 RHOH CD3D	8.58e-06	195	109	6	4bdedd924564a260841a9153604026b57487c83d
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 ACTA2 LDB2 ZFHX4 LTBP1 PID1	8.58e-06	195	109	6	cad6563cc51d212554152c727fc2c249c6a07e4d
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB4 FN1 ACTA2 ACTC1 ACTG2 LTBP1	8.58e-06	195	109	6	eb2003d4f15cad213d17eda8ab7479f5a0c62164
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB4 FN1 ACTA2 ACTC1 ACTG2 LTBP1	8.58e-06	195	109	6	44f67437ea65d530133a0240b17f9860d9cc0e99
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 ACTA2 LDB2 ZFHX4 LTBP1 PID1	8.58e-06	195	109	6	783bfa8110161cbd6def50ce849cae676c39c458
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SGSM1 STARD8 MID2 ARHGEF12 LDB2 PTPRM	8.58e-06	195	109	6	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 ZNF423 LDB2 PTPRM PBX1 IL4R	8.83e-06	196	109	6	023312af38f816a44b407e0daa32590d953caf99
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 FN1 ACTA2 ZFHX4 LTBP1 PID1	8.83e-06	196	109	6	3a6c942e2907aa07b5e12dbf9019d18f7bfca507
ToppCell	IPF-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	PAG1 MBNL1 MALT1 RHOH CD3D PCNX1	8.83e-06	196	109	6	6e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-Collagen+matrisome-high_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 FN1 ACTA2 ZFHX4 LTBP1 PID1	8.83e-06	196	109	6	bba88e91cd3e3a6f5a9b443e3a4da33c5b455e70
ToppCell	COPD-Lymphoid-T\|Lymphoid / Disease state, Lineage and Cell class	PAG1 MBNL1 MALT1 RHOH CD3D PCNX1	8.83e-06	196	109	6	c9bdd505c3ab380ed7b272aa518df31a0a706a06
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 ACTA2 LDB2 ZFHX4 LTBP1 PID1	9.09e-06	197	109	6	09946ee8dfb15a2a32da06e5b331f3277ee934f4
ToppCell	Bronchial-NucSeq-Stromal-Peri/Epineurial_-NAF_endoneurial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	MYO7A RGS22 LYSMD4 KBTBD12 LTBP1 IL17RD	9.09e-06	197	109	6	6806ec223e542f0475303698eb78c1cc527f5c6b
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)\|343B / Donor, Lineage, Cell class and subclass (all cells)	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	9.09e-06	197	109	6	78d45d11820ec379942c4c3defd619d5f8cc8e1f
ToppCell	343B-Fibroblasts-Fibroblast-K_(Pericytes)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	9.09e-06	197	109	6	31bc9fd679d78550541d4158568e8dd09ff29e8e
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 FN1 ACTA2 ZFHX4 LTBP1 PID1	9.36e-06	198	109	6	79576525a10ed3e3a9d1608077cd16ecda23376f
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)\|390C / Donor, Lineage, Cell class and subclass (all cells)	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	9.36e-06	198	109	6	c82a151f9f1477d4a401457173b8d72af776c137
ToppCell	390C-Fibroblasts-Fibroblast-K_(Pericytes)-\|390C / Donor, Lineage, Cell class and subclass (all cells)	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	9.36e-06	198	109	6	dc63b56bb6291e527b172d603569376286262845
ToppCell	Tracheal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 PHF24 ACTA2 ACTC1 ACTG2 LTBP1	9.63e-06	199	109	6	8ff0fdcbe9661b013913731ec8b53d84836ca865
ToppCell	Tracheal-10x3prime_v2-Stromal-Myofibroblastic\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	FN1 ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	9.63e-06	199	109	6	534dcfe8b65ad92bb8d749d1c7036ad4807e09cd
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTG2 ZFHX4 DIXDC1	9.63e-06	199	109	6	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	COVID-19-kidney-Fibroblast-1\|kidney / Disease (COVID-19 only), tissue and cell type	PAG1 FN1 ACTA2 LDB2 LTBP1 PID1	9.63e-06	199	109	6	9503646ff1ad248181146ce767e9d12e882ec3bd
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1 LTBP1	9.91e-06	200	109	6	9169a9ec8e9ab95d90a64c5a19ac666a5cf82313
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1 LTBP1	9.91e-06	200	109	6	a3a1e35934d676c39f917652e50c502cb2f613c1
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTG2 DIXDC1 LTBP1	9.91e-06	200	109	6	9d5b3c2dcfa55d50acc2ce2c319d51aa525d4cd1
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTG2 DIXDC1 LTBP1	9.91e-06	200	109	6	87827041663013f5e7273168dc8709d69840e7ce
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ACTA2 ACTG2 ZFHX4 DIXDC1 LTBP1 PBX1	9.91e-06	200	109	6	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	TCEA3 FN1 SYNE1 ACTA2 ACTG2 DIXDC1	9.91e-06	200	109	6	67dcbd86fbc79fd585d0793f979e4aac100326c9
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTG2 DIXDC1 LTBP1	9.91e-06	200	109	6	dcdaec3ca3a3024dc1b8788c417003f84c2bffdc
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1	9.91e-06	200	109	6	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte-Pericyte_3\|LPS_only / Treatment groups by lineage, cell group, cell type	SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1 LTBP1	9.91e-06	200	109	6	7c62678cf408aaaf98d6df0fb27814d2007c4521
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	TCEA3 SYNE1 ACTA2 ACTC1 ACTG2 DIXDC1	9.91e-06	200	109	6	77631c471cc5d453a749784f838cfa6408caf09b
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	STARD8 ITGB8 SPTBN5 PTK2B ZFHX4	3.19e-05	148	109	5	d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	STARD8 MAN2B2 GPR65 RHOH IL4R	3.86e-05	154	109	5	79ebda35dd1719e157738d7c13e5b8ccc3991f03
ToppCell	PND03-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD4_T-CD4_T_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	CENPL PHF24 AP4E1 CD3D DNMT1	4.50e-05	159	109	5	a5509f0604ef0caef5ed1af83dd89c86686c73cc
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Lymphocytic-T_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GPR65 MALT1 RHOH CD3D H3C1	4.63e-05	160	109	5	97c899df1b57fd2bd1867e02bfedf1920c00ad17
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 PAG1 DHX9 RHOH CD3D	4.91e-05	162	109	5	80317c4253bf8e897782e562f29835f181c65b98
ToppCell	PND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GPR65 JADE1 CHML SGO2 ULK2	5.52e-05	166	109	5	bb8135119dc37fdbba476599a56d368f422688dc
ToppCell	facs-Marrow-T_cells-18m-Myeloid\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 ALAS1 FGR G6PD PID1	5.52e-05	166	109	5	fab4da2537904ad114218f720e18a600f14a00a1
ToppCell	severe-Myeloid-Eosinophils\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SYNE1 ITGB8 RHOH PLA2G6 ALAS1	6.18e-05	170	109	5	863f0266d5837cdbc3e09a3fe6a99dd3e6261674
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 GPR65 RHOH OSBPL6 ALAS1	6.53e-05	172	109	5	3a37569a5902f3c65ff8d3912421309a8c82ee9b
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Mast_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 GPR65 RHOH OSBPL6 ALAS1	6.53e-05	172	109	5	cc9d9dae290f11f8c348c78228af4e49469dc93b
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell_prolif\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FN1 SYNE1 LDB2 PTPRM PBX1	6.53e-05	172	109	5	c056d44e2e130ceccadfcdceb192a7f095d779c8
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SYNE1 ZNF423 LDB2 PBX1 IL4R	6.71e-05	173	109	5	afa6bb19df52541d8d17cbfac9cbdd18a5f3632d
ToppCell	368C-Myeloid-Mast_cell\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PAG1 GPR65 RHOH OSBPL6 PBX1	6.71e-05	173	109	5	8cffb4a37d30b6626188309b868ac4a62e91262f
ToppCell	368C-Myeloid-Mast_cell-\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	PAG1 GPR65 RHOH OSBPL6 PBX1	6.71e-05	173	109	5	fb87ea74bf70aa83b458edf728c81857c8b8eb96
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGS22 NCDN DIXDC1 ULK2 PID1	7.08e-05	175	109	5	b8995e7ada85ba959f06264a0295b61e390c4e6c
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-stromal_related-T_reticular\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	RGS22 NCDN DIXDC1 ULK2 PID1	7.08e-05	175	109	5	7ae76bd3b4f610b2f98716a4456437cd3696b686
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 THRSP KBTBD12	7.47e-05	177	109	5	c9b02a2e1ff2aa18c37e88a53b06a5b696a442ae
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ACTA2 ACTC1 ACTG2 THRSP KBTBD12	7.47e-05	177	109	5	7ebdcedfe02da6d05bba3d625d8bd4c4ea96e4ad
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-proliferative_fibroblast\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ACTA2 LDB2 ZFHX4 LTBP1 PID1	7.47e-05	177	109	5	b872ee91e01265b101b81bd304cf6b95d5419e68
ToppCell	TCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6\|TCGA-Ovary / Sample_Type by Project: Shred V9	FN1 SYNE1 ACTA2 ACTG2 LDB2	7.68e-05	178	109	5	142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PAG1 ACTA2 LDB2 ZFHX4 PID1	7.68e-05	178	109	5	d4ecb84e9b1f4ec49c519321156aa10f9bd34cce
ToppCell	COVID-19-Heart-VSMC\|Heart / Disease (COVID-19 only), tissue and cell type	ACTA2 HIPK2 ACTG2 JADE1 IL4R	7.88e-05	179	109	5	a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LRRN1 ACTA2 ACTG2 ZFHX4 DIXDC1	7.88e-05	179	109	5	02c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCell	Control-Stromal-SMC\|Control / Disease state, Lineage and Cell class	ACTA2 ACTC1 ACTG2 LTBP1 PBX1	7.88e-05	179	109	5	1378051bc62009eec2dbecf3d5d89baedbeb84eb
ToppCell	facs-Spleen-nan-3m-Lymphocytic\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SMG1 ACTA1 MBNL1 ACTA2 PTK2B	8.09e-05	180	109	5	87fb1fdbc49c808bb5f6fe9fb747057b45fa78d0
ToppCell	severe-Myeloid-Eosinophils\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	SYNE1 ITGB8 RHOH PLA2G6 ALAS1	8.09e-05	180	109	5	ac03812b1409435c55d323a7516deeac82bd3509
ToppCell	wk_08-11-Mesenchymal-Fibroblast-Mesenchymal_1\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	ACTA2 ACTG2 LDB2 ZFHX4 METTL21C	8.30e-05	181	109	5	7e3bcfa2ba5b98a7df5854aa6e7a31e9a71faa8a
ToppCell	3'-Pediatric_IBD-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	FN1 ACTA2 ACTG2 DIXDC1 LTBP1	8.30e-05	181	109	5	ab0f300d14b62cef57f1b0bdae143b8dfe8e6975
ToppCell	wk_15-18-Hematologic-Meg-ery-Definitive_erythroblast\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	SDE2 WDR26 PTK2B ZNF451 USP7	8.52e-05	182	109	5	93841f730ca1a735eaaf5f2ccbe5c45ab0e029d1
ToppCell	wk_20-22-Hematologic-Meg-ery-Definitive_erythroblast\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SDE2 ARHGEF12 WDR26 ZNF451 USP7	8.52e-05	182	109	5	0c77ef4556c1d1512ebe9077df858b28f9e38dd5
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic-SMC_(PLPP2+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POGK ACTA2 ACTC1 ACTG2 TRAPPC9	8.52e-05	182	109	5	dfde2d9950f445c6c936ac828f7210de87bb45ec
ToppCell	PBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)	TCEA3 PAG1 MALT1 RHOH CD3D	8.52e-05	182	109	5	9ba85f621a846531a2a7861e9df695d288c9e149
ToppCell	5'-GW_trimst-1-SmallIntestine-Mesenchymal-myocytic\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	POGK ACTA2 ACTC1 ACTG2 TRAPPC9	8.52e-05	182	109	5	52274af3136d4fd4a495f5882618444661421f0f
ToppCell	Pericytes-Donor_03\|World / lung cells shred on cell class, cell subclass, sample id	ACTA1 ACTA2 ACTC1 ACTG2 LTBP1	8.75e-05	183	109	5	d04deef7cd4e1738227a6593b84874ce0168c773
ToppCell	COVID-19-kidney-Mito-rich_EC\|kidney / Disease (COVID-19 only), tissue and cell type	FN1 SYNE1 ZNF423 LDB2 PBX1	8.75e-05	183	109	5	3c4153479fc4ab2d073d92cee120480015555914
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c11-GNLY\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	LAMB4 GPR65 SYNE1 CD3D DNMT1	8.75e-05	183	109	5	90c66ffd2c1f87c91f9a9886e28aeec542f9df85
ToppCell	3'-Child09-12-SmallIntestine-Mesenchymal-myocytic-myofibroblast\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMB4 FN1 ACTA2 ACTG2 LTBP1	8.75e-05	183	109	5	6b5eef96b28911c752a8b6c0975918c4572cec38
Computational	Muscle genes.	ACTA1 ACTA2 ACTC1 ACTG2	3.57e-05	37	55	4	MODULE_512
Computational	Genes upregulated in subsets of cells of a given type within various tumors	SMG1 SYNE1 CHD2 GOLGA4	1.10e-04	49	55	4	GAVISH_3CA_METAPROGRAM_CD8_T_CELLS_CHROMATIN
Computational	Genes in the cancer module 387.	ACTA1 ACTA2 ACTC1 ACTG2	1.10e-04	49	55	4	MODULE_387
Computational	Genes in the cancer module 329.	ACTA1 ACTA2 ACTC1 ACTG2	1.28e-04	51	55	4	MODULE_329
Drug	blebbistatin	FN1 MYO7A ACTA1 ACTA2 ACTC1 ACTG2 PTK2B MTOR DIXDC1	4.70e-09	116	109	9	CID003476986
Drug	AC1L1HS4	FN1 ACTA1 ACTA2 ACTC1 ACTG2	4.17e-07	32	109	5	CID000004267
Drug	Nsc687160	ACTA1 ACTA2 ACTC1 ACTG2	1.44e-06	18	109	4	CID005459290
Drug	tolytoxin	ACTA1 ACTA2 ACTC1 ACTG2	1.82e-06	19	109	4	CID006440827
Drug	m2-19	ACTA1 ACTA2 ACTC1 ACTG2	1.82e-06	19	109	4	CID000079129
Drug	NSC529592	FN1 ACTA1 ACTA2 HIPK2 ACTC1 ACTG2 USP7 G6PD DNMT1	1.92e-06	234	109	9	CID000014403
Drug	plakin	SYNE1 ACTA1 ACTA2 ACTC1 ACTG2 SPTBN5	2.73e-06	82	109	6	CID000018752
Drug	NSC312786	ACTA1 ACTA2 ACTC1 ACTG2	2.79e-06	21	109	4	CID000329495
Drug	AC1L8NVR	ACTA1 ACTA2 ACTC1 ACTG2	2.79e-06	21	109	4	CID000384633
Drug	NSC613009	MYO7A ACTA1 ACTA2 ACTC1 ACTG2 PTK2B MTOR	3.09e-06	130	109	7	CID000003800
Drug	AC1Q6LQU	FN1 ACTA1 ACTA2 ACTC1 ACTG2	3.33e-06	48	109	5	CID000072380
Drug	Thioproperazine dimesylate [2347-80-0]; Down 200; 6.2uM; MCF7; HT_HG-U133A	ACTG2 SCLY NEK9 NCDN CD3D PLA2G6 ULK2 IL4R	4.73e-06	196	109	8	2236_DN
Drug	Minoxidil [38304-91-5]; Down 200; 19.2uM; MCF7; HT_HG-U133A	FN1 MID2 ZNF423 ACTA2 MED1 NDRG3 LTBP1 TRAPPC9	4.91e-06	197	109	8	1496_DN
Drug	Caffeic acid [3331-39-5]; Up 200; 22.2uM; HL60; HT_HG-U133A	LAMB4 OR7E24 NEK9 ITPR3 SPTBN5 PTK2B ZFHX4 TRAPPC9	5.09e-06	198	109	8	3053_UP
Drug	NSC 523214	FN1 ACTA1 ACTA2 ACTC1 ACTG2 SPTBN5 PTK2B	6.97e-06	147	109	7	CID000004752
Drug	NSC3096	FN1 ACTA1 ACTA2 ACTC1 ACTG2 GOLGA4	7.72e-06	98	109	6	CID000002832
Drug	Actinomycin D	FN1 OFD1 ACTA1 ACTA2 ACTC1 ACTG2 PTK2B H3C1 ALAS1 PBX1 G6PD IL4R	7.91e-06	523	109	12	CID000002019
Drug	dihydrocytochalasin B	ACTA1 ACTA2 ACTC1 ACTG2 FGR	8.58e-06	58	109	5	CID000003064
Drug	CID5288653	ACTA1 ACTA2 ACTC1 ACTG2	9.31e-06	28	109	4	CID005288653
Drug	azaspiracid	ACTA1 ACTA2 ACTC1 ACTG2	1.24e-05	30	109	4	CID006451158
Drug	nocodazole	FN1 ACTA1 ACTA2 ACTC1 ACTG2 NEK9 ITPR3 PTK2B MTOR DIXDC1 GOLGA4	1.84e-05	477	109	11	CID000004122
Drug	N,N'-p-phenylenedimaleimide	ACTA1 ACTA2 ACTC1 ACTG2	2.06e-05	34	109	4	CID000076765
Drug	1,N6-ethenoadenosine 5'-diphosphate	ACTA1 ACTA2 ACTC1 ACTG2	2.06e-05	34	109	4	CID000001312
Drug	AC1NSKFN	ACTA1 ACTA2 ACTC1 ACTG2	2.60e-05	36	109	4	CID005311324
Drug	C3H2N2O3S	FN1 ACTA1 ACTA2 ACTC1 ACTG2	2.84e-05	74	109	5	CID000448652
Drug	SIRIUS	FN1 ACTA1 ACTA2 ACTC1 ACTG2	3.44e-05	77	109	5	CID000091750
Drug	AC1L9EF8	ACTA1 ACTA2 ACTC1 ACTG2 MALT1	3.90e-05	79	109	5	CID000443315
Drug	phosphatidate	ACTA1 ACTA2 ACTC1 ACTG2 NCDN PTK2B H3C1 MTOR PLA2G6 DAGLA	4.36e-05	432	109	10	CID005460104
Drug	epsilon-ATP	ACTA1 ACTA2 ACTC1 ACTG2	4.39e-05	41	109	4	CID000162262
Drug	AC1L1JYL	GPR65 FN1 ACTA1 ACTA2 ACTC1 ACTG2 NCDN PTK2B MTOR PLA2G6	4.54e-05	434	109	10	CID000005262
Drug	Chelidonine monohydrate (+) [476-32-4]; Up 200; 10.8uM; MCF7; HT_HG-U133A	LAMB4 FN1 ITGB8 NCDN SPTBN5 CD3D PTPRM	4.62e-05	197	109	7	2779_UP
Drug	Benzamil hydrochloride [2898-76-2]; Down 200; 11.2uM; HL60; HT_HG-U133A	ACTA2 CHML NEK9 HIPK3 PTK2B RHOH ULK2	4.77e-05	198	109	7	2200_DN
Drug	Methyldopa (L,-) [555-30-6]; Down 200; 19uM; MCF7; HT_HG-U133A	FN1 MID2 MED1 ZFHX4 PLA2G6 IL4R NPAT	4.77e-05	198	109	7	5272_DN
Drug	Famotidine [76824-35-6]; Up 200; 11.8uM; MCF7; HT_HG-U133A	TRAPPC11 OR7E24 MED1 NEK9 RHOH PTPRM PCNX1	4.77e-05	198	109	7	1529_UP
Drug	Bicuculline (+) [485-49-4]; Down 200; 10.8uM; MCF7; HT_HG-U133A	LAMB4 ARHGEF12 ACTG2 CD3D PLA2G6 DIXDC1 TRAPPC9	4.77e-05	198	109	7	4397_DN
Drug	Dicyclomine hydrochloride [67-92-5]; Down 200; 11.6uM; MCF7; HT_HG-U133A	ZNF423 ACTG2 MED1 NDRG3 NCDN HIPK3 IL4R	4.92e-05	199	109	7	1483_DN
Drug	Minocycline hydrochloride [13614-98-7]; Down 200; 8uM; MCF7; HT_HG-U133A	FN1 NDRG3 NCDN ITPR3 MTOR IRAK4 PCNX1	4.92e-05	199	109	7	7436_DN
Drug	MgCl2	ACTA1 ACTA2 PTDSS1 ACTC1 ACTG2 SPTBN5 H3C1 DIXDC1 G6PD	5.22e-05	354	109	9	CID000024584
Drug	AC1OAGFB	FN1 ACTA1 ACTA2 ACTC1 ACTG2 ITPR3 SPTBN5 MALT1 CD3D MTOR DAGLA	5.60e-05	539	109	11	CID006857345
Drug	AC1L8FNU	ACTA1 ACTA2 ACTC1 ACTG2	5.82e-05	44	109	4	CID000425429
Drug	2-hexadecyne	SYNE1 G6PD	6.79e-05	3	109	2	CID014009124
Drug	candesartan cilexetil	FN1 ACTA1 ACTA2 ACTC1 ACTG2 DIXDC1	7.11e-05	145	109	6	CID000002540
Drug	PI(3,4,5)P3	ACTA1 ACTA2 ACTC1 ACTG2 PTK2B MTOR	7.96e-05	148	109	6	CID000643963
Drug	C18:1n-7	ACTA1 ACTA2 ACTC1 ACTG2 THRSP	8.10e-05	92	109	5	CID000122325
Drug	NpCaM	ACTA1 ACTA2 ACTC1 ACTG2	8.22e-05	48	109	4	CID000122259
Drug	manidipine	ACTA1 ACTA2 ACTC1 ACTG2 ITPR3	9.43e-05	95	109	5	CID000004008
Drug	AC1L1KMJ	LAMB4 FN1 MYO7A ACTA1 ACTA2 ACTC1 ACTG2 SPTBN5 PTK2B MTOR	9.76e-05	476	109	10	CID000030956
Drug	NSC106399	ACTA1 ACTA2 ACTC1 ACTG2	1.04e-04	51	109	4	CID000002887
Drug	sulphoxide	SYNE1 ACTA1 ACTA2 ACTC1 ACTG2	1.26e-04	101	109	5	CID000008442
Drug	IWR-1 compound	FN1 ACTA2	1.35e-04	4	109	2	ctd:C585534
Drug	3-methylhistidine	ACTA1 ACTA2 ACTC1 ACTG2	1.40e-04	55	109	4	CID000064969
Drug	NSC618487	FN1 POGK ACTA1 ACTA2 ACTC1 ACTG2 NEK9 ITPR3 PTK2B H3C1 IRAK4 PLA2G6 FGR DAGLA	1.47e-04	933	109	14	CID000005279
Drug	Formyl	FN1 ACTA1 ACTA2 ACTC1 ACTG2 ITPR3 PID1	1.51e-04	238	109	7	CID000123370
Drug	D-triiodothyronine	ACTA1 ACTA2 ACTC1 ACTG2 MED1 THRSP GPR149 DIXDC1 G6PD	1.56e-04	409	109	9	CID000000861
Drug	iodomethylate	SYNE1 TCFL5 DNMT1	1.76e-04	23	109	3	CID000123359
Disease	Moyamoya disease (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.05e-08	8	105	4	DOID:13099 (implicated_via_orthology)
Disease	autosomal dominant nonsyndromic deafness 20 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.05e-08	8	105	4	DOID:0110550 (implicated_via_orthology)
Disease	Baraitser-Winter syndrome 1 (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.05e-08	8	105	4	DOID:0081112 (implicated_via_orthology)
Disease	thoracic aortic aneurysm (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	1.05e-08	8	105	4	DOID:14004 (implicated_via_orthology)
Disease	intestinal atresia (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	3.13e-08	10	105	4	DOID:10486 (implicated_via_orthology)
Disease	patent ductus arteriosus (implicated_via_orthology)	ACTA1 ACTA2 ACTC1 ACTG2	3.13e-08	10	105	4	DOID:13832 (implicated_via_orthology)
Disease	juvenile idiopathic arthritis	LAMB4 ACTA2 RHOH LTBP1 PID1	6.87e-06	74	105	5	EFO_0002609
Disease	pulse pressure measurement	FN1 ZNF423 MBNL1 ACTA2 NEK7 ARHGEF12 CHD2 NEK9 LDB2 CD3D H3C1 ZFHX4 LTBP1 FGR TRAPPC9 GOLGA4 DNMT1	8.24e-06	1392	105	17	EFO_0005763
Disease	Ureteral obstruction	FN1 ACTA2 HIPK2	8.39e-05	24	105	3	C0041956
Disease	Left Ventricular Hypertrophy	FN1 ACTA1 MTOR	9.51e-05	25	105	3	C0149721
Disease	diabetic angiopathy (implicated_via_orthology)	FN1 PTK2B	1.86e-04	6	105	2	DOID:11713 (implicated_via_orthology)
Disease	peripheral vascular disease	HIPK3 CSTPP1	2.60e-04	7	105	2	EFO_0003875
Disease	Kartagener Syndrome	OFD1 ODAD2 DNAH1	2.64e-04	35	105	3	C0022521
Disease	Ciliary Dyskinesia, Primary, 1, With Or Without Situs Inversus	OFD1 ODAD2 DNAH1	2.64e-04	35	105	3	C4551906
Disease	Polynesian Bronchiectasis	OFD1 ODAD2 DNAH1	2.64e-04	35	105	3	C4317124
Disease	vital capacity	FN1 SYNE1 MBNL1 ODAD2 MED1 WDR26 ITGB8 OSBPL6 LTBP1 PBX1 DAGLA PID1 OTOG	4.49e-04	1236	105	13	EFO_0004312
Disease	alpha wave measurement, electroencephalogram measurement	DNAH1 METTL21C	5.54e-04	10	105	2	EFO_0004357, EFO_0006870
Disease	Primary Ciliary Dyskinesia	OFD1 ODAD2 DNAH1	6.34e-04	47	105	3	C4551720
Disease	Nephrosclerosis	ACTA2 HIPK2	6.76e-04	11	105	2	C0027719
Disease	smoking behavior, BMI-adjusted waist circumference	ZNF423 ITGB8 H3C1 LTBP1	9.64e-04	122	105	4	EFO_0004318, EFO_0007789
Disease	ureidopropionic acid measurement	PAG1 OTOG	1.46e-03	16	105	2	EFO_0010542
Disease	glomerulonephritis (is_marker_for)	FN1 PTK2B	2.06e-03	19	105	2	DOID:2921 (is_marker_for)
Disease	Colonic Neoplasms	ACTA2 ACTG2 MTOR DNMT1	2.16e-03	152	105	4	C0009375
Disease	Malignant tumor of colon	ACTA2 ACTG2 MTOR DNMT1	2.54e-03	159	105	4	C0007102
Disease	amino acid measurement	MOXD2P GPR65 LRRN1 SYNE1 PTDSS1 ODAD2 LTBP1 HTT	2.95e-03	678	105	8	EFO_0005134
Disease	Alveolitis, Fibrosing	FN1 ACTA2 MTOR	3.27e-03	83	105	3	C4721507
Disease	Pulmonary Fibrosis	FN1 ACTA2 MTOR	3.50e-03	85	105	3	C0034069

Protein segments in the cluster

Peptide	Gene	Start	Entry
DAVDIHYPENEMTCN	COP1	456	Q8NHY2
YVHLNADELEALQMC	DENND10P1	216	Q6NSW5
DKESTVQVHYRMCQS	CD3D	81	P04234
LVDECEDMQLSYIHS	DNMT1	816	P26358
IHETTYNSIMKCDID	ACTA1	276	P68133
HCMKREADEATNYNS	DIXDC1	471	Q155Q3
IHETTYNSIMKCDID	ACTA2	276	P62736
HETTYNSIMKCDIDI	ACTG2	276	P63267
CMKYSIHEGQTVQVD	ADAMTS20	931	P59510
CADSQSQIMEYIHKI	ARHGEF12	1496	Q9NZN5
TEYIHSNAMEVCNNE	AP4E1	911	Q9UPM8
VCQQHSEQMYSDLIK	CACUL1	171	Q86Y37
IQHTEAFCYASQDME	CHML	96	P26374
DSDLMEAFHCNQTQV	RAD1	206	O60671
VYEAVTKNIHESCMS	G6PD	146	P11413
ELAEYHQAKESCNME	OFD1	146	O75665
THEDCITEVKMAYVN	ITPR3	1401	Q14573
HCAELYTNQMSTETE	NPAT	466	Q14207
NFEDMQEITQHFAVC	NDRG3	76	Q9UGV2
EKYEQACNEFTTHVM	PBX1	166	P40424
EGDYQLVQHEVLCSM	HIPK2	181	Q9H2X6
LVQHEVLCSMTNTYE	HIPK2	186	Q9H2X6
NHTCLVFEMLEQNLY	HIPK2	271	Q9H2X6
SLYVAICNMHQFIDE	IL17RD	541	Q8NFM7
VQSEIFLHESYCMDT	LYSMD4	181	Q5XG99
EETASHYRMAALEQC	NCDN	711	Q9UBB6
QYSLELIQMVHSCLD	NEK9	276	Q8TD19
ELVQHYMEVNDGLCN	FGR	221	P09769
CTVTELSDFLQAMEH	MALT1	101	Q9UDY8
TEVCDELMSRHNIYV	ALAS1	541	P13196
ETVSSHFEMRCQYQE	GOLGA4	1761	Q13439
YHNSSITVDCDQCTM	LDB2	111	O43679
EINDDLSYQMDCHAV	PID1	186	Q7Z2X4
VNTFVMYLCEQLDIH	PCNX1	1136	Q96RV3
YHLDTAKMTCVDVNE	LTBP1	1651	Q14766
DHYSEELRQLVNMCI	NEK7	261	Q8TDX7
LNMHCVITEIKAQYD	KRT87P	101	A6NCN2
QSSAVMALQEACEAY	H3C1	86	P68431
LMVVEYAESTNNCQA	POGK	206	Q9P215
QHEVLCSMKNTYEVL	HIPK3	186	Q9H422
LNTLQHLCEEMEYSE	OSBPL6	596	Q9BZF3
DENSIFYHNLMNSEC	GPR149	421	Q86SP6
FYHNLMNSECETTKD	GPR149	426	Q86SP6
MALCQYLEEHAEELN	METTL21C	96	Q5VZV1
CALMEQQHYVDQTSE	ITGB8	661	P26012
ITHMYSAEGEEVQLC	DNAH1	1371	Q9P2D7
KVEMSEQQHTFYCQE	HTT	1761	P42858
CHLLMDDVVSADNYT	IL4R	86	P24394
FAETHNCVDLMQAAE	KLHL12	141	Q53G59
AQRHVLTYMEDAVCQ	CSTPP1	16	Q9H6J7
TQEEVDLFMDCLYSH	CENPL	276	Q8N0S6
LIHNSCVSAMQEYEE	CHD2	1176	O14647
HEEICTTNEGVMYRI	FN1	466	P02751
FHNTEVEAMQAESCY	CTR9	296	Q6PD62
EDCELSHSVYENFML	CCDC144B	606	Q3MJ40
DCPSMQEQHSIDDEY	GLMP	246	Q8WWB7
IDTNDNTVTVCMDYI	MBNL1	211	Q9NR56
DCYIVLLDQDTNLMH	MAN2B2	586	Q9Y2E5
ENMTAVDIVYTSCHD	DAGLA	361	Q9Y4D2
QKHMQLCEDYRTDEN	LAMB4	1526	A4D0S4
VEAMYSVASQCLHEK	IRAK4	426	Q9NWZ3
AMAYLESINCVHRDI	PTK2B	536	Q14289
EDCELSHSVYENFML	CCDC144A	606	A2RUR9
YVHLNADELEALQMC	DENND10	216	Q8TCE6
YQQQCHEMAERLEDS	SDE2	156	Q6IQ49
QEYFLEDCIQMTHFV	DHX9	571	Q08211
VMDVQDSTHVSCKLY	MED1	466	Q15648
LEENQITEMTDYCLQ	LRRN1	126	Q6UXK5
LDYHCTSVVMLNDVD	PTPRM	1276	P28827
VAINVLMHDSYDVCL	KBTBD12	586	Q3ZCT8
SQLDEEFMHSVENVC	OTOG	2661	Q6ZRI0
VECHYQTLDRDSMTF	MOXD2P	441	A6NHM9
VSCHMLSELEEVIQY	MTOR	1591	P42345
CASHVSRMLNYIEQE	ROPN1B	176	Q9BZX4
TETYKVLQEHMDLCQ	SYNE1	1586	Q8NF91
TTSAYQEHEKMCQQL	SYNE1	4776	Q8NF91
EMDLQLTNIEHFSEC	SYNE1	8126	Q8NF91
DEDETINVNYNIMCL	RGS22	101	Q8NE09
VDMQTHSRVISYEGC	OR7E24	101	Q6IFN5
ALYQLSEDADNCITM	ODAD2	986	Q5T2S8
ADVVLMCYSVANHNS	RHOH	76	Q15669
ASVEYQEHLCAMTGV	SMG1	1121	Q96Q15
NIMYLIVETVHQECE	STRIP1	221	Q5VSL9
HYMEVNSNEKESCDQ	SGO2	961	Q562F6
EILVELVQYCHTQMD	PLA2G6	166	O60733
RCYDNMNHAIETEEG	JADE1	181	Q6IE81
DILSEDSTLTCMQHY	PAG1	91	Q9NWQ8
DSTLTCMQHYEEVQT	PAG1	96	Q9NWQ8
CMQHYEEVQTSASDL	PAG1	101	Q9NWQ8
HYCDNINLLLTEEEM	PHF24	186	Q9UPV7
QDMVLQLCSSYSAAE	STARD8	781	Q92502
VDNSHFMSAEVTECL	SPTBN5	3381	Q9NRC6
TASEVYQSMEILHCL	ERVK-9	836	P63128
IHETTYNSIMKCDID	ACTC1	276	P68032
DEARMFCQENYSHLV	CLEC17A	276	Q6ZS10
LVTQNCEAYEAHMRD	SCLY	311	Q96I15
DSQEYVKQHCMSLAS	ZNF451	616	Q9Y4E5
DSMDATDQVVYKHCT	ZFHX4	2306	Q86UP3
TNEMYCLVVTVQSHE	TRAPPC11	766	Q7Z392
MYSQEDHIFQLCSTD	SAGE2P	1	A6NJ88
LYATVTHNVCDERME	SAGE2P	161	A6NJ88
IKQVECMDDHYASQA	STKLD1	56	Q8NE28
VFCDHNYTVEDTMHQ	THAP1	131	Q9NVV9
DAEVHYISREMCNSE	TMPRSS12	226	Q86WS5
NCDKMASEIEDHIYQ	TCEA3	211	O75764
VDEQIHACYAQTMAE	SGSM1	646	Q2NKQ1
MNSTCIEEQHDLDHY	GPR65	1	Q8IYL9
YNCAVEMVQSAALDE	ULK2	966	Q8IYT8
MMHQIYSCSDENIEV	VXN	1	Q8TAG6
CYDMFHNLTTIINEV	ZBED9	1151	Q6R2W3
YMQCAEDHQTLLVVV	TRAPPC9	6	Q96Q05
MEDESIYTCDHCQQD	ZNF423	61	Q2M1K9
FIDHQNIEEECSSMD	WDR26	646	Q9H7D7
LDHENEKVNMYCVSD	MID2	196	Q9UJV3
YVCRVVSAMINSNDD	TGM7	221	Q96PF1
NCLLTVMDRYAAEVH	THRSP	11	Q92748
EVEYTQLQHILCSHM	TCFL5	51	Q9UL49
ETLDSFMQHDVQELC	USP7	286	Q93009
TREADVMEYAVNCHV	PTDSS1	141	P48651
ERDQMESTLNYEDHC	KIAA2013	386	Q8IYS2
SDHVMDAISQCEQYA	MYO7A	1316	Q13402
LECALHTDMADIEQY	NAT8L	161	Q8N9F0