Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

1.00e-0641193IPR029423
DomainLRRC37AB_C

LRRC37A3 LRRC37A2 LRRC37A

1.00e-0641193PF14914
DomainLRRC37_N

LRRC37A3 LRRC37A2 LRRC37A

1.00e-0641193IPR032754
DomainLRRC37

LRRC37A3 LRRC37A2 LRRC37A

1.00e-0641193PF15779
DomainLRRC37A/B-like

LRRC37A3 LRRC37A2 LRRC37A

1.00e-0641193IPR015753
DomainAUTS2

FBRS FBRSL1

1.20e-0431192IPR023246
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

ENGASE FLNC NR2F6 SHROOM3 ZNF48 KMT2B MYO9B SPEG FBRS ADGRB2 FBRSL1 LMTK2 LAMB2 GTF2IRD1 GBA2 PLEKHG5 ABCA7 WDR59 GRAMD2A ZNF263 FAM20C FASN INTS5 PWWP2B PROM2 MTHFR HELZ2 CPSF1 TNK2 CACNA1H CEP170B

2.93e-1911051253135748872
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A3 LRRC37A2 LRRC37A

1.81e-074125322419166
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

SHROOM3 SLC4A7 BAG3 HJURP LMTK2 CBX4 ARHGEF17 WDR59 FAM171A1 ARHGEF1 MAP3K10 HELZ PATJ CEP170B DNMT1

5.16e-078611251536931259
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

NR2F6 KMT2B BAG3 GTF2IRD1 GTF3C4 FASN INTS5 PWWP2B BAZ2A HELZ2 CPSF1 HELZ CCDC9 DNMT1

8.17e-077741251415302935
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A3 LRRC37A2 LRRC37A

5.34e-0610125323064749
Pubmed

The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.

SHANK1 FLNC MIA3 SLC4A7 NOL6 HJURP MXRA8 FBRS LAMB2 CBX4 GTF3C4 ZNF263 FASN INTS5 CEBPZ PBXIP1

6.89e-0612031251629180619
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

SHROOM3 SLC4A7 ZNF48 KMT2B NOL6 LAMB2 MSL1 CBX4 COL18A1 INTS5 BAZ2A CEBPZ HELZ2 HELZ CTNND2 PATJ PBXIP1 CEP170B

7.02e-0614971251831527615
Pubmed

MLL4 binds TET3.

KMT2B TET3

1.28e-052125238579707
Pubmed

Relationships among MTHFR a1298c gene polymorphisms and methylation status of Dact1 gene in transitional cell carcinomas.

DACT2 MTHFR

1.28e-052125223244112
Pubmed

FLNC myofibrillar myopathy results from impaired autophagy and protein insufficiency.

FLNC BAG3

1.28e-052125226969713
Pubmed

Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.

SHANK1 ASXL1 USP6 TET3 CDK4

1.90e-0590125515033168
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

DXO SLC4A7 ZNF48 LRRC37A3 ADGRB2 PLEKHG5 CREBZF USP6 CEBPZ PROM2 ARHGEF1 NEURL4 DNMT1

3.02e-059251251328986522
Pubmed

Relationship between Nutrition, Lifestyle, and Neurodegenerative Disease: Lessons from ADH1B, CYP1A2 and MTHFR.

CYP1A2 MTHFR

3.84e-053125236011409
Pubmed

Glyphosate and AMPA Induce Alterations in Expression of Genes Involved in Chromatin Architecture in Human Peripheral Blood Mononuclear Cells (In Vitro).

TET3 DNMT1

3.84e-053125233803994
Pubmed

Aciculin interacts with filamin C and Xin and is essential for myofibril assembly, remodeling and maintenance.

FLNC XIRP1

3.84e-053125224963132
Pubmed

Contribution to Alzheimer's disease risk of rare variants in TREM2, SORL1, and ABCA7 in 1779 cases and 1273 controls.

ABCA7 TREM2

3.84e-053125228789839
Pubmed

Complete loss of murine Xin results in a mild cardiac phenotype with altered distribution of intercalated discs.

FLNC XIRP1

3.84e-053125219843512
Pubmed

Filamin C is a highly dynamic protein associated with fast repair of myofibrillar microdamage.

FLNC XIRP1

3.84e-053125227206985
Pubmed

Physical mapping of human myosin-IXB (MYO9B), the human orthologue of the rat myosin myr 5, to chromosome 19p13.1.

NR2F6 MYO9B

3.84e-05312529226381
Pubmed

A combined laser microdissection and mass spectrometry approach reveals new disease relevant proteins accumulating in aggregates of filaminopathy patients.

FLNC XIRP1

3.84e-053125223115302
Pubmed

Differential involvement of sarcomeric proteins in myofibrillar myopathies: a morphological and immunohistochemical study.

FLNC XIRP1

3.84e-053125219151983
Pubmed

A human MAP kinase interactome.

SHANK1 FLNC BAG3 LAMB2 RASAL3 ARHGEF1 MAP3K10 HELZ TNK2

6.89e-05486125920936779
Pubmed

The TIP60 Complex Is a Conserved Coactivator of HIF1A.

MYO9B SAMHD1 PRPF6 FASN CPSF1

7.58e-05120125527320910
Pubmed

Plcg2M28L Interacts With High Fat/High Sugar Diet to Accelerate Alzheimer's Disease-Relevant Phenotypes in Mice.

MTHFR TREM2

7.65e-054125235813947
Pubmed

Primary Biliary Cholangitis in British Columbia First Nations: Clinical features and discovery of novel genetic susceptibility loci.

TRAF3IP2 DNMT1

7.65e-054125229297981
Pubmed

LRF-mediated Dll4 repression in erythroblasts is necessary for hematopoietic stem cell maintenance.

EPOR DLL4

7.65e-054125223134786
Pubmed

Association of CNK1 with Rho guanine nucleotide exchange factors controls signaling specificity downstream of Rho.

ARHGEF1 MAP3K10

7.65e-054125215753034
Pubmed

De novo DNA methylation drives 5hmC accumulation in mouse zygotes.

TET3 DNMT1

7.65e-054125226751286
Pubmed

In vivo validation of late-onset Alzheimer's disease genetic risk factors.

ABCA7 MTHFR TREM2

9.84e-0525125338687251
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

FNIP2 ASXL1 SPEG ARHGEF17 BAZ2A CACNA1H TET3 CEP170B

1.17e-04407125812693553
Pubmed

Association of polymorphisms in DNMT1, DNMT3A, DNMT3B, MTHFR and MTRR genes with global DNA methylation levels and prognosis of autoimmune thyroid disease.

MTHFR DNMT1

1.27e-045125223039890
Pubmed

New N-RAP-binding partners alpha-actinin, filamin and Krp1 detected by yeast two-hybrid screening: implications for myofibril assembly.

FLNC NOL6

1.27e-045125212692149
Pubmed

Frequent somatic mutations in epigenetic regulators in newly diagnosed chronic myeloid leukemia.

ASXL1 TET3

1.27e-045125228452984
Pubmed

Unusual splicing events result in distinct Xin isoforms that associate differentially with filamin c and Mena/VASP.

FLNC XIRP1

1.27e-045125216631741
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNC NOL6 PRPF6 FASN BAZ2A CEBPZ HELZ2 CPSF1 HELZ DNMT1

1.30e-046531251022586326
Pubmed

TBX1 is required for normal stria vascularis and semicircular canal development.

CREBZF STAB1 TBX1

1.89e-0431125331550482
Pubmed

Corepressor-dependent silencing of fetal hemoglobin expression by BCL11A.

EPOR DNMT1

1.90e-046125223576758
Pubmed

Chromosomal location of three unconventional myosin heavy chain genes in the mouse.

CYP1A2 MYO9B

1.90e-04612528954808
Pubmed

DNA Methylation-Mediated Modulation of Endocytosis as Potential Mechanism for Synaptic Function Regulation in Murine Inhibitory Cortical Interneurons.

TET3 DNMT1

1.90e-046125232147726
Pubmed

The calcium-independent receptor for alpha-latrotoxin from human and rodent brains interacts with members of the ProSAP/SSTRIP/Shank family of multidomain proteins.

SHANK1 ADGRB2

1.90e-046125210964907
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

ASXL1 MYO9B MSL1 GTF3C4 FASN HELZ2 DNMT1

2.07e-04332125737433992
Pubmed

Dynamics of DNA hydroxymethylation and methylation during mouse embryonic and germline development.

TET3 DNMT1

2.66e-047125236539615
Pubmed

Tails of unconventional myosins.

MYO9B MYO15A

2.66e-047125211212352
Pubmed

The PHD finger/bromodomain of NoRC interacts with acetylated histone H4K16 and is sufficient for rDNA silencing.

BAZ2A DNMT1

2.66e-047125216085498
Pubmed

ASXL1 mutations promote myeloid transformation through loss of PRC2-mediated gene repression.

ASXL1 CBX4

2.66e-047125222897849
Pubmed

The functional interactome of PYHIN immune regulators reveals IFIX is a sensor of viral DNA.

RBM12B NOL6 COL18A1 BAZ2A CEBPZ HELZ DNMT1

2.80e-04349125725665578
Pubmed

Genomic analysis of mouse retinal development.

NR2F6 KMT2B HJURP BTBD17 GBA2 CREBZF STAB1 GRAMD2A BAZ2A ROBO3 PRMT7 CDK4

2.84e-0410061251215226823
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

MIA3 SLC4A7 MXRA8 WDR59 GTF3C4 CEBPZ HELZ PATJ CORO7 DNMT1

3.28e-047331251034672954
Pubmed

Mutation of ARHGAP9 in patients with coronary spastic angina.

MYO9B ARHGEF17 ARHGEF1

3.49e-0438125319911011
Pubmed

Development of lung cancer before the age of 50: the role of xenobiotic metabolizing genes.

CYP1A2 MTHFR

3.54e-048125217259654
Pubmed

Myofibrillar Myopathy – RETIRED CHAPTER, FOR HISTORICAL REFERENCE ONLY

FLNC BAG3

3.54e-048125220301672
Pubmed

DNA methyltransferase 3b regulates articular cartilage homeostasis by altering metabolism.

TET3 DNMT1

3.54e-048125228614801
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

FLNC MYO9B NOL6 BAG3 PRPF6 WDR59 GTF3C4 FASN BAZ2A CEBPZ ARHGEF1 CPSF1 CORO7 DNMT1

3.73e-0413531251429467282
Pubmed

Transcription factor Foxp3 and its protein partners form a complex regulatory network.

MSL1 PRPF6 CBX4 FASN CEBPZ ARHGEF1 HELZ

3.97e-04370125722922362
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

RBM12B MYO9B NOL6 HJURP SAMHD1 PRPF6 GTF3C4 CEBPZ NEURL4 DNMT1

4.31e-047591251035915203
Pubmed

PCGF homologs, CBX proteins, and RYBP define functionally distinct PRC1 family complexes.

FBRS FBRSL1 CBX4

4.37e-0441125322325352
Pubmed

TET1 regulates fibroblast growth factor 8 transcription in gonadotropin releasing hormone neurons.

TET3 DNMT1

4.54e-049125231361780
Pubmed

TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.

ASXL1 MYO9B MSL1 SAMHD1 FAM171A1 COL18A1 FASN CPSF1 HELZ PATJ DNMT1

5.11e-049221251127609421
Pubmed

Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo.

KMT2B PRMT7 DNMT1

5.39e-0444125324183668
Pubmed

RNF219/α-Catenin/LGALS3 Axis Promotes Hepatocellular Carcinoma Bone Metastasis and Associated Skeletal Complications.

KMT2B DNMT1

5.66e-0410125233643786
Pubmed

DNA Sequence Recognition of Human CXXC Domains and Their Structural Determinants.

KMT2B TET3

5.66e-0410125229276034
Pubmed

Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.

SHROOM3 PRMT7

5.66e-0410125220700443
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

TRAF3IP2 MIA3 NOL6 FBRSL1 ARHGEF1 HELZ PATJ PBXIP1 DNMT1

5.89e-04650125938777146
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

MIA3 BAG3 SAMHD1 FASN INTS5 FOXRED2 CEBPZ ARHGEF1 CORO7 DNMT1 CDK4

6.10e-049421251131073040
Pubmed

Excess of ovarian nerve growth factor impairs embryonic development and causes reproductive and metabolic dysfunction in adult female mice.

FASN TET3 DNMT1

6.55e-0447125332892421
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

SHANK1 SHROOM3 MIA3 ADGRB2 FAM171A1 ZNF263 STON2 CTNND2 NEURL4 CEP170B DNMT1

7.31e-049631251128671696
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

ZNF48 KMT2B MSL1 PRPF6 CBX4 GTF2IRD1 GTF3C4 INTS5 BAZ2A CEBPZ CPSF1 TET3 DNMT1

7.99e-0412941251330804502
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

KMT2B BAG3 GTF3C4 FASN BAZ2A CEBPZ PATJ DNMT1

8.59e-04549125838280479
Pubmed

Identification of genes contributing to the obese yellow Avy phenotype: caloric restriction, genotype, diet x genotype interactions.

FLNC SHROOM3 FASN

9.31e-0453125315306695
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

SHROOM3 MIA3 FBRSL1 GTF2IRD1 DNAH1 COL23A1 COL18A1 PWWP2B PROM2 TNK2 CACNA1H PATJ TET3 CEP170B

9.51e-0414891251428611215
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

SHROOM3 HJURP RASAL3 STON2 TNK2 PATJ NEURL4

9.60e-04430125735044719
Pubmed

Comparative interactome analysis of α-arrestin families in human and Drosophila.

FLNC LMTK2 LAMB2 CPSF1 NEURL4 PBXIP1

9.70e-04313125638270169
Pubmed

Germline polymorphisms in the one-carbon metabolism pathway and DNA methylation in colorectal cancer.

MTHFR DNMT1

9.74e-0413125219936946
Pubmed

Cdc42 activation by endothelin regulates neural crest cell migration in the cardiac outflow tract.

ARHGEF1 TNK2

9.74e-0413125231219639
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

FLNC MIA3 SLC4A7 BAG3 GBA2 FASN PRMT7 PBXIP1

1.07e-03568125837774976
Pubmed

Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.

MIA3 NOL6 FBRS LMTK2 PRPF6 GTF3C4 CEBPZ

1.10e-03440125734244565
Pubmed

A function for cyclin D1 in DNA repair uncovered by protein interactome analyses in human cancers.

GTF3C4 FASN DNMT1 CDK4

1.10e-03125125421654808
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

SHROOM3 LMTK2 FAM171A1 CPSF1

1.10e-03125125429467281
Pubmed

Myopathy associated LDB3 mutation causes Z-disc disassembly and protein aggregation through PKCα and TSC2-mTOR downregulation.

FLNC BAG3

1.13e-0314125233742095
Pubmed

Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.

FBRS PRPF6 CBX4 STON2 NEURL4 CEP170B

1.25e-03329125634316702
Pubmed

Down-regulation of active ACK1 is mediated by association with the E3 ubiquitin ligase Nedd4-2.

BAG3 TNK2

1.30e-0315125219144635
Pubmed

TET2 catalyzes active DNA demethylation of the Sry promoter and enhances its expression.

TET3 DNMT1

1.30e-0315125231530896
Pubmed

EHMT2 directs DNA methylation for efficient gene silencing in mouse embryos.

TET3 DNMT1

1.30e-0315125226576615
Pubmed

Identification of neuroglycan C and interacting partners as potential susceptibility genes for schizophrenia in a Southern Chinese population.

LAMB2 STAB1 MTHFR

1.47e-0362125319367581
Pubmed

The Amot/Patj/Syx signaling complex spatially controls RhoA GTPase activity in migrating endothelial cells.

PLEKHG5 PATJ

1.49e-0316125218824598
Pubmed

A pharmacogenetic study to investigate the role of dietary carcinogens in the etiology of colorectal cancer.

CYP1A2 MTHFR

1.49e-0316125212419832
Pubmed

TBX1 regulates epithelial polarity and dynamic basal filopodia in the second heart field.

PATJ TBX1

1.49e-0316125225371366
Pubmed

A systems-wide screen identifies substrates of the SCFβTrCP ubiquitin ligase.

FLNC BAG3 HJURP GTF2IRD1 HELZ

1.55e-03232125525515538
Pubmed

K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors.

SHROOM3 MIA3 BAG3 GTF2IRD1 STON2 CPSF1 PRMT7 DNMT1

1.57e-03604125838803224
Pubmed

Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms.

NOL6 BAG3 CREG1 WDR59 FOXRED2 CEBPZ NEURL4 PBXIP1 DNMT1

1.66e-03754125933060197
Pubmed

MicroRNA-related genetic variations as predictors for risk of second primary tumor and/or recurrence in patients with early-stage head and neck cancer.

BAG3 COL18A1 MTHFR CDK4

1.67e-03140125420819778
Pubmed

Cbx4 regulates the proliferation of thymic epithelial cells and thymus function.

DLL4 CBX4

1.68e-0317125223362346
Pubmed

Systematic analysis of candidate genes for Alzheimer's disease in a French, genome-wide association study.

CH25H MTHFR

1.68e-0317125220413850
Pubmed

The EGFR-ZNF263 signaling axis silences SIX3 in glioblastoma epigenetically.

ZNF263 CEBPZ DNMT1

1.76e-0366125332051553
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

LMTK2 GTF2IRD1 USP6 STON2 TNK2 NEURL4 DNMT1

1.82e-03481125728190767
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

FLNC RBM12B BTBD17 PRPF6 CBX4 GTF2IRD1 ZMAT5 INTS5 HELZ2 CPSF1 PBXIP1

1.85e-0310821251138697112
Pubmed

Oct4 Methylation-Mediated Silencing As an Epigenetic Barrier Preventing Müller Glia Dedifferentiation in a Murine Model of Retinal Injury.

TET3 DNMT1

1.89e-0318125227895551
Pubmed

Growth disturbance in fetal liver hematopoiesis of Mll-mutant mice.

EPOR CDK4

1.89e-031812529639506
Pubmed

A quantitative chaperone interaction network reveals the architecture of cellular protein homeostasis pathways.

ZNF843 BAG3 SAMHD1 HSFX1 MYO15A CDK4

2.05e-03363125625036637
Pubmed

TRIM65 regulates microRNA activity by ubiquitination of TNRC6.

MYO9B NOL6 HJURP FBRS PRPF6 CEBPZ

2.08e-03364125624778252
InteractionTOP3B interactions

ENGASE FLNC NR2F6 SHROOM3 ZNF48 KMT2B MYO9B SPEG FBRS ADGRB2 FBRSL1 LMTK2 LAMB2 GTF2IRD1 GBA2 PLEKHG5 ABCA7 WDR59 GRAMD2A ZNF263 FAM20C FASN INTS5 PWWP2B PROM2 MTHFR HELZ2 CPSF1 HELZ TNK2 CACNA1H CEP170B

1.50e-10147012332int:TOP3B
GeneFamilyZinc fingers CXXC-type

KMT2B TET3 DNMT1

1.41e-0512743136
GeneFamilyUPF1 like RNA helicases

HELZ2 HELZ

8.87e-04117421169
CoexpressionPEREZ_TP53_TARGETS

FNIP2 FLNC FAM13C FBRSL1 KCP CBX4 ARHGEF17 ABCA7 GRAMD2A USP6 COL18A1 LRRC37A NRK FAM167A TREM2 CES3 ILDR1 CEP170B

1.61e-05120112518M4391
CoexpressionGSE12963_ENV_NEF_VS_ENV_NEF_AND_VPR_DEFICIENT_HIV1_INF_CD4_TCELL_UP

KMT2B FBRS GRAMD2A BAZ2A HELZ2 HELZ

4.55e-051341256M455
CoexpressionGSE2585_THYMIC_MACROPHAGE_VS_MTEC_UP

MYO9B ABCA7 FAM171A1 TNK2 PRMT7 CORO7 PBXIP1

4.60e-051971257M6279
CoexpressionGSE17721_LPS_VS_PAM3CSK4_1H_BMDC_DN

EPOR XIRP1 CBX4 FAM20C CACNA1H PRMT7 DNMT1

4.90e-051991257M3912
CoexpressionGSE24574_NAIVE_VS_TCONV_CD4_TCELL_UP

TRAF3IP2 MYO9B SPEG MXRA8 CBX4 TNK2 PBXIP1

5.06e-052001257M8328
CoexpressionGSE2405_S_AUREUS_VS_A_PHAGOCYTOPHILUM_NEUTROPHIL_DN

MYO9B FBRS ABCA7 MTHFR HELZ2 HELZ PBXIP1

5.06e-052001257M6208
CoexpressionLAIHO_COLORECTAL_CANCER_SERRATED_DN

ENGASE ASXL1 GTF2IRD1 ZNF263 CCDC9

5.50e-05851255M17423
CoexpressionAtlasfacebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2

SHANK1 ENGASE FLNC ADAMTS4 MYO9B BAG3 MXRA8 ADGRB2 KCP LAMB2 CBX4 ZNF25 GBA2 KIAA1614 COL23A1 FASN FOXRED2 NRK FAM167A CACNA1H GGACT

4.93e-06122812021facebase_RNAseq_e14.5_palate_poster_nasal_Tgfbr2_WT_2500_K2
ToppCellAT1-AT2_cells-Donor_02|World / lung cells shred on cell class, cell subclass, sample id

MXRA8 DACT2 LMTK2 ABCA7 GRAMD2A COL18A1 FAM167A CTNND2

5.04e-0818312586821dca076318115d360ff426eb1218cfe104063
ToppCellFetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FLNC ADAMTS4 COL23A1 COL18A1 STON2 ROBO3 TBX1

8.74e-071831257bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell3'-Pediatric_IBD-SmallIntestine-Mesenchymal-Pericytes-Pericyte|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 FAM13C LAMB2 TDO2 ARHGEF17 COL18A1 NTN4

1.43e-061971257452be45f4aac8459dd860493171f5f715368d663
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC XIRP1 ADAMTS4 SPEG ARHGEF17 COL18A1 CACNA1H

1.48e-061981257705118a5db366b43ffd3389c60e4cb392ad3f2e6
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic-Muscle_smooth_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 FAM13C SPEG MXRA8 ARHGEF17 COL18A1 CACNA1H

1.53e-0619912577c272a1aa7f3e931ad5d20809719d85b3bce4cb0
ToppCellBiopsy_Other_PF-Mesenchymal-Smooth_Muscle_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

ADAMTS4 FAM13C SPEG MXRA8 ARHGEF17 COL18A1 CACNA1H

1.58e-06200125755ac281901309e30978da1f7489386e54489721e
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM12B SPEG PRPF40B PROM2 GGACT NEURL4

4.54e-061521256acfafdb64bd5b0eb7371b04cfef51ed2798e9b30
ToppCellfacs-Marrow-T_cells-18m-Lymphocytic-common_lymphoid_progenitor_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RBM12B SPEG PRPF40B PROM2 GGACT NEURL4

4.54e-0615212569d6c88ceca0569dbeb12e488acec7fcb7f972f03
ToppCellPND07-Endothelial-Endothelial_lymphatic|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC CH25H STAB1 COL18A1 ROBO3 TBX1

6.31e-061611256133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC CH25H STAB1 COL18A1 ROBO3 TBX1

6.31e-0616112569466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC CH25H STAB1 COL18A1 ROBO3 TBX1

6.31e-061611256cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCellPrimary_Motor_Cortex_(M1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1_FGFR3_MT1G|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PAMR1 BAG3 LAMB2 ZNRF4 STON2 PBXIP1

9.21e-06172125655fba5ce0ead1114e1a76f67ad68432c6bac90e5
ToppCellAdult-Mesenchymal-pericyte_cell-D231|Adult / Lineage, Cell type, age group and donor

FAM13C SPEG KCP ARHGEF17 COL18A1 CACNA1H

9.21e-061721256858cee96c1c06160863b4adcd7023c0d678bd50f
ToppCellfacs-Skin-nan-24m-Epithelial-outer_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FAM13C MXRA8 LAMB2 CCDC187 MYO15A TBX1

1.02e-051751256f1166b567bca80dac3abe90c3dc544c831006640
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 KCP STAB1 FAM20C TREM2 CTNND2

1.31e-0518312568e9d45c96b44558158e3d59613f64a73d5390c19
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 KCP STAB1 FAM20C TREM2 CTNND2

1.31e-0518312560408d991ddb639594b45d5cb2432dd29289167b1
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FNIP2 KCP STAB1 FAM20C TREM2 CTNND2

1.31e-05183125679f05b8a967124d831b0baef137e30659f5917a7
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

FNIP2 KCP STAB1 FAM20C TREM2 CTNND2

1.35e-05184125692202e1cd0bba1ce4b061ebcb8a2af5bb590542a
ToppCellBAL-Control-Myeloid-Macrophage|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 KCP STAB1 FAM20C TREM2 CTNND2

1.35e-0518412567331535d469453a5264dcb0270a97f63d3b55201
ToppCellBAL-Control-Myeloid-Macrophage-transitional_Macro|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

FNIP2 KCP STAB1 FAM20C TREM2 CTNND2

1.35e-051841256337e38a6b2b6770cc992d88b006829f194841b10
ToppCelldroplet-Heart-4Chambers-21m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENGASE HJURP STAB1 COL23A1 STON2 TBX1

1.39e-051851256bb5a4cf93534b9bcd0923f314c389d571e91e7f8
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPOR NR2F6 PAMR1 KCP STAB1 ZMAT5

1.39e-0518512561b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

EPOR NR2F6 PAMR1 KCP STAB1 ZMAT5

1.39e-05185125602cbf492bc40abebaa93a3a208888afae72fbe06
ToppCelldroplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC DLL4 STAB1 COL18A1 STON2 TBX1

1.44e-051861256f23f21781a758541f59c06efa7739d26a03fb478
ToppCelldroplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC DLL4 STAB1 COL18A1 STON2 TBX1

1.44e-0518612560de87109da9324c597fadf2eb782f0f158afe832
ToppCellLA-04._Ventricular_Cardiomyocyte_I|LA / Chamber and Cluster_Paper

HJURP CCDC187 DMRTC2 ILDR1 CTNND2

1.48e-05110125534dcd1e1e16e8b6088ff9a7a40532e8bd000c121
ToppCellAdult-Endothelial-endothelial_cell_of_lymph_vessel-D175|Adult / Lineage, Cell type, age group and donor

FLNC ADAMTS4 COL23A1 FAM171A1 STON2 TBX1

1.48e-0518712561e52d3d9d664c813d859b5b75e4c07b218818f95
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC HJURP STAB1 COL18A1 STON2 TBX1

1.62e-051901256a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC HJURP STAB1 COL18A1 STON2 TBX1

1.62e-0519012560bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCellfacs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC HJURP STAB1 COL18A1 STON2 TBX1

1.62e-05190125626e2237f65cb43723c5da853831b40df2982d6e4
ToppCellfacs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC HJURP STAB1 COL23A1 COL18A1 TBX1

1.67e-05191125648823a97c38263f2c6e58348214f5b62773a6368
ToppCellfacs-Pancreas|facs / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PAMR1 CPA1 ARHGEF17 FAM20C GDAP1L1 CTNND2

1.67e-051911256d48e5f67d384226add7d7fb2a124954136e09a82
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC DLL4 STAB1 COL18A1 STON2 TBX1

1.67e-05191125651cff0594ac7ad8c065c8ea2301f8c149bd062b4
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC DLL4 STAB1 COL18A1 STON2 TBX1

1.67e-051911256a55b6f0a7ec1a8852ffca593cfdccd7edea09b7b
ToppCelldroplet-Lung-30m-Endothelial-lymphatic_endothelial|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC DLL4 STAB1 COL18A1 STON2 TBX1

1.67e-05191125638681a1b182d6af5cce85db5431b6eba4b20ad96
ToppCellfacs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC HJURP STAB1 COL23A1 COL18A1 TBX1

1.67e-0519112560eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro-stroma|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FLNC PAMR1 DACT2 ADGRB2 NTN4 NRK

1.72e-0519212564ed5040594ba2d0639f0990697504ecef872ca70
ToppCell10x5'v1-week_12-13-Mesenchymal_fibro|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

FLNC PAMR1 DACT2 ADGRB2 NTN4 NRK

1.72e-051921256d4f5d6653564c2c5d0f5f7c932d89cb1b1412844
ToppCellLA-04._Ventricular_Cardiomyocyte_I|World / Chamber and Cluster_Paper

HJURP CCDC187 DMRTC2 ILDR1 CTNND2

1.76e-051141255ca69dddbdc02fa5718c56362649cd4b9b54f94ce
ToppCellmetastatic_Brain-Fibroblasts-Pericytes|metastatic_Brain / Location, Cell class and cell subclass

ADAMTS4 PAMR1 FAM13C MXRA8 ARHGEF17 COL18A1

1.82e-051941256d1889a3e22d5b88461c81ec3ea0e74bb9bf63e60
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

1.82e-0519412568f19e553f18c313c2a2ff9453884b9484b255d71
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

1.82e-05194125667fbb81b7d20cb63be27b2a2beea5b5689f8e08c
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

1.82e-051941256f95935153bd2c4c3c7b2b729da6f7e98b45fed79
ToppCellCOVID-19-lung-Pericytes/_Smooth_Muscle|lung / Disease (COVID-19 only), tissue and cell type

ADAMTS4 FAM13C SPEG ARHGEF17 COL18A1 CACNA1H

1.82e-0519412565e1e0513a54ec4cf0b247ec85c9fbc68dfac1da3
ToppCellParenchymal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC ADAMTS4 FAM13C SPEG COL18A1 CACNA1H

2.04e-051981256bd42c03e384e64f61b02618cf1a5440033bb04b2
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 SPEG ADGRB2 ARHGEF17 COL18A1 CACNA1H

2.04e-0519812567dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC ADAMTS4 FAM13C SPEG COL23A1 CACNA1H

2.04e-051981256c12e7511628db819a52959bb68580e27c00c2e41
ToppCellControl-Control-Lymphocyte-T/NK-CD4+_T_activated|Control / Disease, condition lineage and cell class

ASXL1 MXRA8 PLEKHG5 LRRC37A HELZ2 PBXIP1

2.04e-051981256ee71543559836fd59adc0da877b2ca538cba60cb
ToppCellParenchymal-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 SPEG MXRA8 ARHGEF17 COL18A1 CACNA1H

2.10e-05199125620f760d92c351a1dac4cc0a424c443ea03a179fe
ToppCellBronchial-10x5prime-Stromal-Myofibroblastic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

XIRP1 ADAMTS4 SPEG ARHGEF17 COL18A1 CACNA1H

2.10e-051991256ad75e5e26c37a97331164d7f77235ebd9a933a44
ToppCelldistal-3-mesenchymal-Pericyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FAM13C MXRA8 KCP ARHGEF17 COL18A1 CACNA1H

2.16e-052001256911db29f254bb697610e720ba78816e2c7f57933
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

2.16e-052001256d70bad979299615fcba707ba21296020918705e6
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FLNC ADAMTS4 FAM13C SPEG COL18A1 CACNA1H

2.16e-052001256a66449b22b39dd6987fc2c3ed160d24564234ced
ToppCellParenchymal-10x3prime_v2-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

2.16e-05200125638c21ec379005f688df33aea65237a063c476c2e
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW13-Mesenchymal-Mesoderm|GW13 / Sample Type, Dataset, Time_group, and Cell type.

FNIP2 LRRC37A2 KCTD11 ZNF263 GGACT MYO15A

2.16e-0520012560f4b8b0868bda406fe6bf01d1b722510fdfd0168
ToppCelldistal-mesenchymal-Airway_Smooth_Muscle-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

FLNC SPEG MXRA8 CPA1 COL18A1 NTN4

2.16e-052001256bc969a956f62570419a5faaf0ab0fd17b343c5ca
ToppCellTracheal-NucSeq-Stromal-Pericyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 FAM13C TDO2 ARHGEF17 COL18A1 CACNA1H

2.16e-05200125678cd0b7d221ef855512ee9ac9a291f61622c2e24
ToppCellParenchymal-10x5prime-Stromal-Pericyte-Muscle_pericyte_pulmonary|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

2.16e-052001256f9bc22ff17bb1c751e6b05bca3f403836f33459a
ToppCellParenchymal-10x5prime-Stromal-Pericyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 FAM13C MXRA8 ARHGEF17 COL18A1 CACNA1H

2.16e-0520012560a7640db28c708003d5da2d19eb651f6fedfd710
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 GRAMD2A NTN4 PATJ NLRP13

3.31e-0513012556434d9106ccb38786dad36fab80163dfc07b6eb7
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNIP2 CAPN12 FBRS LMTK2 STON2

6.15e-051481255b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCellfacs-Marrow-T-cells-3m-Myeloid-granulocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FNIP2 CAPN12 FBRS LMTK2 STON2

6.15e-051481255ba277c898678dd36f8dc1d681301c71901b89055
ToppCellPND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNC CH25H STAB1 COL18A1 ROBO3

9.42e-05162125596c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCellChildren_(3_yrs)-Mesenchymal-vascular_smooth_muscle_cell-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

ADAMTS4 SPEG ARHGEF17 MAP3K10 CACNA1H

9.70e-0516312558f24cef152f5965727bbeee116bd26c75cbba82a
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

FNIP2 LRRC37A2 LRRC37A TET3 CEP170B

9.98e-0516412551aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellwk_15-18-Epithelial-Airway_epithelial_progenitor-epi-prox-progenitor_intermediate_|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

SHROOM3 PCDHGC5 PROM2 ILDR1 CTNND2

1.03e-041651255f6887c64af0f26e33316bc5587487e24d76ece2a
ToppCellAdult-Mesenchymal-vascular_smooth_muscle_cell-D175|Adult / Lineage, Cell type, age group and donor

ZNF48 SPEG ADGRB2 COL18A1 ROBO3

1.09e-041671255c4e321bb87512ea839f324c92c0f1afea891483f
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-1M-Neuronal-cortical_neurons_2|Organoid-1M / Sample Type, Dataset, Time_group, and Cell type.

FBRSL1 GDAP1L1 FAM167A CACNA1H

1.11e-048812543a92f76e4db86486cb265301e6056af791a11a63
ToppCelldroplet-Kidney-KIDNEY-1m-Myeloid-nan|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ENGASE ZNF48 FBRS CH25H RASAL3

1.21e-041711255d9ad6a3bce3556abd24af1630bf4a99594437c3a
ToppCellAT1-AT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

FLNC LAMB2 PROM2 CACNA1H PBXIP1

1.25e-0417212550be41df5d35d818deb7316ac21c9366eb4b7bfd1
ToppCellEndothelial-Endothelial-G|Endothelial / shred on cell class and cell subclass (v4)

CH25H STAB1 COL23A1 COL18A1 TBX1

1.25e-041721255644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell390C-Myeloid-Macrophage-M2-like_Macrophage_(MARCO_negative)|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

KCTD11 STAB1 STON2 TREM2 DNMT1

1.28e-0417312551f725ff16e28636b20ef26f3fa9be8b47c89378d
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 DACT2 GRAMD2A NTN4 PATJ

1.32e-041741255d0e3d15731de6c19c232e3aa492c39d8151cf4ed
ToppCellfacs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC PAMR1 KCP LAMB2 FAM167A

1.32e-0417412551d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJURP STAB1 COL23A1 FOXRED2 TBX1

1.35e-0417512559d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HJURP STAB1 COL23A1 FOXRED2 TBX1

1.35e-041751255f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCellPND10-Immune-Immune_Myeloid-Monocytic-Macrophage|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NR2F6 SAMHD1 CREG1 STAB1 TREM2

1.35e-041751255a8b05972e1bec4de73feaa6c4a9bcbe6b50c8044
ToppCell3'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 FAM13C ARHGEF17 COL18A1 CACNA1H

1.43e-041771255452ec2df36c6d656a7cdadc55be545ccdb146a29
ToppCell5'-Parenchyma_lung-Mesenchymal-Mesenchymal_Myocytic-pericyte_cell-Pericytes-Pericytes_L.2.3.3.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ADAMTS4 FAM13C ARHGEF17 COL18A1 CACNA1H

1.50e-041791255dc6cd46fa652b296ddbc41855f6377946d0a4cdc
ToppCellSmart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-A|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MYO9B CH25H ABCA7 STAB1 TREM2

1.50e-0417912553d3716078afdb9a89ddfadb3197cd1b52fa770be
ToppCellAT1-AT2_cells-SSc-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

MXRA8 FAM171A1 COL18A1 CACNA1H C3orf36

1.54e-0418012553c7b2033821f9e34e2924bd8655f566edcbcc7d3
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 SPEG CH25H LAMB2 CACNA1H

1.54e-041801255af2bafcd1b2082629de3ea336711add01565c4c4
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 SPEG CH25H LAMB2 CACNA1H

1.54e-041801255f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellBAL-Control-cDC_8|Control / Compartment, Disease Groups and Clusters

GTF3C4 CREBZF PRPF40B MAP3K10 ROBO3

1.58e-041811255f370161afef2ec827a7b194c06abb9ac1a507cbb
ToppCellControl-Epithelial_alveolar-AT_1-AT1-AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 DACT2 GRAMD2A NTN4 FAM167A

1.62e-041821255a95956ce4adccb34cc0c47ebfa1878ce4617904e
ToppCellCOVID-19-Heart-CM_3|Heart / Disease (COVID-19 only), tissue and cell type

FNIP2 FLNC XIRP1 KCP CTNND2

1.62e-041821255287fcc3897ae08841f6f85ae6c9cef16f75b1dd1
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Macrophages|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PCDHGC5 SAMHD1 CREG1 STAB1 COL23A1

1.62e-041821255ea39b1b5db185b0cb11dfa2e01f3f972effbd770
ToppCelltumor_Lung-Fibroblasts-Pericytes|tumor_Lung / Location, Cell class and cell subclass

ADAMTS4 FAM13C ARHGEF17 COL18A1 CACNA1H

1.67e-041831255a03dd563af9b15cb1f5de5732a229405a9f82d84
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 DACT2 GRAMD2A NTN4 FAM167A

1.67e-04183125506ac66726ec53db810ebb90ec69cfdb903da53f6
ToppCellAdult-Mesenchymal-pericyte_cell-D122|Adult / Lineage, Cell type, age group and donor

FAM13C KCP ARHGEF17 COL18A1 CACNA1H

1.67e-041831255fc31a43a637423cb3bb9aa184a3a889a0b9aaea6
ToppCelldroplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Endothelial-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FLNC HJURP STON2 ROBO3 TBX1

1.67e-041831255919c9861073d12fd12aecd7469b1478b13838c43
ToppCellPericytes-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

FLNC FAM13C SPEG MXRA8 COL18A1

1.71e-041841255cd10d351d91a81dd6dc806cb4e0c8d7861c98e0b
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 DACT2 GRAMD2A NTN4 PATJ

1.71e-0418412557cc5796557379c3d1db078c1aeda40659c6e401c
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Mesenchymal|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

XIRP1 SPEG MXRA8 LAMB2 CACNA1H

1.71e-041841255c9d7ec17cc5b7ba1b1e721ca392746e8f4a3d41f
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FLNC SHROOM3 PAMR1 ARHGEF17 C17orf58

1.71e-041841255e33e2a887aafba7b6a31f00bb0dbe974b4359fd6
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

NTN4 STON2 KLHDC7A CTNND2 PATJ

1.71e-041841255fa4915b0498f3069fd5ef497286445528f75187e
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1-AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 GRAMD2A NTN4 FAM167A PATJ

1.75e-0418512553bef59cc0aa939d2a7e52f0f6c61bc00528fe50b
ToppCellmetastatic_Lymph_Node-Fibroblasts-COL14A1+_matrix_FBs|metastatic_Lymph_Node / Location, Cell class and cell subclass

FLNC PAMR1 MXRA8 DACT2 ROBO3

1.75e-041851255506eee2c1b6e8acec3aa8b2c66868010006c4c14
ToppCellLPS_only-Epithelial_alveolar-AT_1-AT1-AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

SHROOM3 DACT2 GRAMD2A NTN4 FAM167A

1.75e-04185125568f428e169cfb77de970bdfdeea9b9f16f68d2ba
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMB2 STAB1 COL23A1 COL18A1 TBX1

1.75e-0418512553a4ae836e882e8d29eb0a2dfab5677f10f2d365f
DrugFoliosidine [2520-38-9]; Down 200; 13uM; MCF7; HT_HG-U133A

EPOR NR2F6 MIA3 CBX4 PPP1R15A CREBZF MTHFR CES3 CACNA1H PATJ

1.20e-07197123104761_DN
Drugnocodazole; Down 200; 1uM; MCF7; HG-U133A

MIA3 NOL6 ARHGEF17 CREBZF FOXRED2 BAZ2A CTNND2 PRMT7 CCDC9

1.33e-061981239621_DN
DrugKarakoline [39089-30-0]; Down 200; 10.6uM; PC3; HT_HG-U133A

TRAF3IP2 NR2F6 KMT2B ADGRB2 LMTK2 CREBZF FOXRED2 BAZ2A CTNND2

1.38e-0619912393741_DN
DrugChlorpromazine hydrochloride [69-09-0]; Up 200; 11.2uM; HL60; HT_HG-U133A

EPOR BAG3 FBRS CBX4 PPP1R15A GTF2IRD1 BAZ2A PBXIP1

1.03e-0519312381864_UP
DrugLaudanosine (R,S) [1699-51-0]; Down 200; 11.2uM; MCF7; HT_HG-U133A

ENGASE CYP1A2 KMT2B NOL6 CREBZF ZMAT5 FOXRED2 PBXIP1

1.29e-0519912382890_DN
DiseaseLiposarcoma, Pleomorphic

FASN CDK4

9.46e-0541182C0205825
DiseaseNeural Tube Defects

CYP1A2 SHROOM3 MTHFR

2.34e-04301183C0027794
Diseaseliposarcoma

FASN CDK4

2.35e-0461182C0023827
DiseaseLiposarcoma, well differentiated

FASN CDK4

2.35e-0461182C1370889
DiseaseLiposarcoma, Dedifferentiated

FASN CDK4

2.35e-0461182C0205824
DiseaseMyofibrillar myopathy

FLNC BAG3

2.35e-0461182cv:C2678065
DiseaseMammary Carcinoma, Human

EPOR NR2F6 DLL4 LRRC37A2 FASN LRRC37A MTHFR KLHDC7A DNMT1

2.68e-045251189C4704874
DiseaseMammary Neoplasms, Human

EPOR NR2F6 DLL4 LRRC37A2 FASN LRRC37A MTHFR KLHDC7A DNMT1

2.68e-045251189C1257931
Diseaseinterleukin 10 measurement

SHROOM3 MIA3 FBRSL1 TBX1

2.76e-04781184EFO_0004750
DiseaseMammary Neoplasms

EPOR NR2F6 DLL4 LRRC37A2 FASN LRRC37A MTHFR KLHDC7A DNMT1

2.76e-045271189C1458155
DiseaseBreast Carcinoma

EPOR NR2F6 DLL4 LRRC37A2 FASN LRRC37A MTHFR KLHDC7A DNMT1

3.21e-045381189C0678222
DiseaseFamilial Dementia

TREM2 DNMT1

4.37e-0481182C0751071
DiseaseSenile Paranoid Dementia

TREM2 DNMT1

4.37e-0481182C0338630
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

KMT2B KCP FAM167A TET3 CEP170B

6.20e-041701185EFO_0000685, EFO_0007791, EFO_0007837
Diseasecoffee consumption measurement

FNIP2 DXO CYP1A2 C17orf58 PWWP2B

8.42e-041821185EFO_0006781
Diseasesystolic blood pressure, alcohol consumption measurement

SLC4A7 MTHFR FAM167A

8.89e-04471183EFO_0006335, EFO_0007878
Diseaseretinopathy of prematurity (biomarker_via_orthology)

EPOR DLL4

1.02e-03121182DOID:13025 (biomarker_via_orthology)
Diseasetetralogy of Fallot (is_implicated_in)

MTHFR TBX1

1.20e-03131182DOID:6419 (is_implicated_in)
Diseaseanemia (is_implicated_in)

EPOR MTHFR

1.40e-03141182DOID:2355 (is_implicated_in)
Diseasehypertension

CYP1A2 SLC4A7 MYO9B FBRSL1 KCP MTHFR

1.50e-033071186EFO_0000537
DiseasePROSTATE CANCER, HEREDITARY, 1

MYO9B FBRSL1 COL23A1

1.81e-03601183C4722327
DiseaseDementia

TREM2 DNMT1

2.07e-03171182C0497327
Diseaserheumatoid arthritis

KMT2B KCP GTF2IRD1 FAM167A TET3 CEP170B TBX1

2.62e-034621187EFO_0000685
DiseaseProstate cancer, familial

MYO9B FBRSL1 COL23A1

2.70e-03691183C2931456
DiseaseNonorganic psychosis

SHANK1 TDO2 TBX1

2.70e-03691183C0349204
Diseasedilated cardiomyopathy

FLNC BAG3

2.87e-03201182EFO_0000407
Diseaseparental longevity

SHROOM3 PAMR1 CH25H ADGRB2 FBRSL1 LAMB2 PRPF40B

3.78e-034941187EFO_0007796
DiseaseMalignant neoplasm of breast

EPOR NR2F6 XIRP1 DLL4 LRRC37A2 ZNF25 FASN LRRC37A MTHFR KLHDC7A DNMT1

3.90e-03107411811C0006142

Protein segments in the cluster

PeptideGeneStartEntry
HRAAAWEPTEPPDGD

ADGRB2

1566

O60241
EAWNRLHRAPPSFPA

FBRSL1

731

Q9HCM7
PGWRELVPPDTLHSL

ARHGEF1

396

Q92888
DPPWAAPHVVGSDDL

CCDC187

71

A0A096LP49
RHIPLAPGSDWRDLP

DNMT1

1426

P26358
SHDAAWPFLEPVNPR

BAZ2A

1811

Q9UIF9
DFWRGPAHPGSPIDV

CPA1

51

P15085
FHALEAWLGRARPPP

BTBD17

231

A6NE02
AWHAPGDDLRPEALP

DLL4

121

Q9NR61
LDWPSEERGPVLAHL

CEP170B

1041

Q9Y4F5
STLEGAPEWAAPHPE

C3orf36

66

Q3SXR2
APEWAAPHPEEQRRS

C3orf36

71

Q3SXR2
DPREFGWRDPELPEV

CTNND2

541

Q9UQB3
TPREDWAPKPHAFVG

ASXL1

1351

Q8IXJ9
DRFWDPGPAADPLTD

ABCA7

481

Q8IZY2
ALPRPLHPTPVVDWD

TNK2

611

Q07912
LHPTPVVDWDARPLP

TNK2

616

Q07912
AKPASSPREWDPLHP

HJURP

206

Q8NCD3
PPEDDFRHPREEDWR

RBM12B

606

Q8IXT5
DAPRAPAAGLERWFP

RASAL3

391

Q86YV0
WARHAPFFPELPVAD

NR2F6

216

P10588
HDPELWEDPSEFRPE

CYP1A2

416

P05177
PDAPEAASPAHWPRE

GDAP1L1

31

Q96MZ0
LEHRDSPWHRGPAPA

ARHGEF17

2006

Q96PE2
PLPWALSAHPKRREE

MTHFR

346

P42898
PLPHPRAWFVSLDGR

FAM171A1

701

Q5VUB5
SPHAPTLPADPWDFD

LRRC37A3

71

O60309
TLPADPWDFDHLGPS

LRRC37A3

76

O60309
PFARLLEECWDPDPH

MAP3K10

331

Q02779
SPHAPTLPADPWDFD

LRRC37A2

71

A6NM11
TLPADPWDFDHLGPS

LRRC37A2

76

A6NM11
SPHAPTLPADPWDFD

LRRC37A

71

A6NMS7
TLPADPWDFDHLGPS

LRRC37A

76

A6NMS7
HRESPREPEDSETPW

MYO15A

906

Q9UKN7
RAAEVAPAARAWPDP

C17orf58

61

Q2M2W7
EWTLPDHDRGPLLGP

KIAA1614

191

Q5VZ46
DRDPAPFRAEPTHWC

CPSF1

771

Q10570
AWDPFDPHRLAVAGE

CORO7

551

P57737
PGALDAWAEPHLERL

COL23A1

81

Q86Y22
APAVLHPRPDWEHSA

PCDHGC5

561

Q9Y5F6
REHPHPTARPWRADD

COL18A1

1521

P39060
PPRPGARPTHWATEE

FLNC

1756

Q14315
PIPSRPWDLREGRSH

ILDR1

356

Q86SU0
TPAPDWAPEDHRYIT

NKAIN2

121

Q5VXU1
AHSRPPVPEWDISQD

NOL6

526

Q9H6R4
FPGVPLAPPRHWDDV

LAMB2

186

P55268
NLESPEWTLHPAPEG

LMTK2

1036

Q8IWU2
RATFPPEWAQLPHHD

GGACT

121

Q9BVM4
LEYRPWGPREEPAHL

KMT2B

1781

Q9UMN6
TEQEVRFRPAHWPLP

FOXRED2

541

Q8IWF2
PSWRDHSVEPLRDPN

MSL1

476

Q68DK7
WHFRPPPRGITSSEE

HELZ

166

P42694
DPRLVHLFSWEPGGP

DXO

346

O77932
FDSLEPHREPLPGIW

DNAH1

3601

Q9P2D7
AHVDPEEPWSPCSAR

ADAMTS4

396

O75173
PEELLGLWDSPRSHA

CAPN12

456

Q6ZSI9
AFASPPDPWGRLHRS

FBRS

216

Q9HAH7
PEGAHAAPQPSLEWD

DACT2

521

Q5SW24
HCPLDSAPWDETRDP

DMRTC2

11

Q8IXT2
IPHDIGDPDDEPWLR

GBA2

591

Q9HCG7
RESREAEPHPLWEYP

PRMT7

556

Q9NVM4
DDWPRDVSLPRGAFP

CDK4

236

P11802
RLSPKAAENPDWPHA

FAM20C

191

Q8IXL6
EPSHRYDDQAWARPP

CCDC9

311

Q9Y3X0
WPCPDRHLREKPSLE

FNIP2

701

Q9P278
PDLLAWDPARNTHPP

CBX4

366

O00257
DDPNERPDATVGWHP

DUXB

171

A0A1W2PPF3
ADESGHVVLRWLPPP

EPOR

156

P19235
RWDFAPPLPSDTFAL

KLHDC7A

611

Q5VTJ3
HIRWQPSASEREGPP

ENGASE

626

Q8NFI3
DHGDWDEASRLPPLP

CREG1

36

O75629
WEHRSPPPGLSKFEL

HELZ2

76

Q9BYK8
RFCRGPPWKDPEAEH

GTF2IRD1

86

Q9UHL9
DRVEEPPDYSLHWPE

GRAMD2A

36

Q8IUY3
SAPHPAQPWEGVRDA

CES3

76

Q6UWW8
WDDPDPRLFDHPESP

FASN

961

P49327
QGDDWEPRPLRAASP

BAG3

251

O95817
HGDRWDPTRPPRATD

CACNA1H

736

O95180
FEGAPFPHPLWLRDT

PWWP2B

121

Q6NUJ5
HWARSPALLPHEAPE

CH25H

106

O95992
EPPDPHFSPAELEWV

NEURL4

1531

Q96JN8
EPLEFHAKRPWRPEE

CEBPZ

6

Q03701
HAKRPWRPEEAVEDP

CEBPZ

11

Q03701
EGEARTPLAIPHTPW

PPP1R15A

61

O75807
VSFPGRASPEPRWHL

PAMR1

671

Q6UXH9
ARLEEHTWPFPRPAA

FAM167A

51

Q96KS9
GSPHFHLEWAPRPVE

KCTD11

151

Q693B1
HGEPSQPRWLPDREE

NRK

386

Q7Z2Y5
ETYLHPADPSPAWDD

HSFX1

36

Q9UBD0
FEPTHPERGWIISPL

SLC4A7

891

Q9Y6M7
EAWLERTPGLEPHGF

TDO2

206

P48775
PSAEADWSPGLELHP

SAMHD1

26

Q9Y3Z3
SVDGPLPHPRWSAEA

MIA3

1706

Q5JRA6
PDFRPVHNKSEPAWE

NTN4

476

Q9HB63
PHHPPAWIASARLEE

PRPF6

306

O94906
EEHPEGSRWVPPDSA

KCP

966

Q6ZWJ8
PPPSRAKWAHAARED

SHROOM3

1426

Q8TF72
AGALVEEHAPPSWEP

FAM13C

51

Q8NE31
GAELAWPPEEHARAT

INTS5

826

Q6P9B9
AFRAEWEPPEARAPS

PM20D2

86

Q8IYS1
PVAWIELDAHPPGSA

STON2

406

Q8WXE9
HEPVLRLWGASPPDP

SHANK1

1401

Q9Y566
YPSPWDHEERPAQRD

TRAF3IP2

326

O43734
PRLPRGLRFDHDSWE

PLEKHG5

286

O94827
EPWGPDLHRPEEREP

ZNF48

6

Q96MX3
DSHDPLPSWAELLRP

PBXIP1

566

Q96AQ6
PPAQRHPAWEARGGD

SPEG

2421

Q15772
IWGLSARDDPSHPEA

PROM2

451

Q8N271
PPWPDATIAHNIREE

SAGE1

101

Q9NXZ1
SHWGPPRIVEIFREP

PATJ

1061

Q8NI35
LHPDEEAWLPYSRPS

ROBO3

1316

Q96MS0
DAPWDPCPASELLPH

SYT15B

151

X6R8R1
DEDPSLPGHRPPIWA

ZNRF4

371

Q8WWF5
LDPRQPDWHLDPGLS

CREBZF

111

Q9NS37
RVLLPPEALHWEPDD

STAB1

1706

Q9NY15
PEALHWEPDDAPIPR

STAB1

1711

Q9NY15
TGPPRALWSEHVAPD

PRPF40B

91

Q6NWY9
HDSIARHPAPEDPDW

GTF3C4

791

Q9UKN8
DWEAAPGPAHTARLE

TET3

181

O43151
DPLDHRDAGDLWFPG

TREM2

131

Q9NZC2
SDPDLETPWARHPFG

WDR59

711

Q6PJI9
ISHLERGEAPWGPDP

ZNF621

61

Q6ZSS3
PWILEVEFPHRGFPE

ZNF25

66

P17030
WGPVEADRPPANSHR

ZNF843

126

Q8N446
REWLLDAPELPEGHL

ZMAT5

96

Q9UDW3
RDCDPEDWPRNHRPG

TBX1

296

O43435
LHSLRWEPPADPSPV

XIRP1

941

Q702N8
RLPTDLDIGGPWFPH

USP6

456

P35125
GEVPWSPELGRPHDR

ZNF263

326

O14978
RPHDRSQGDWAPPPE

ZNF263

336

O14978
HFPRIPWANLRAADP

NLRP13

51

Q86W25
HWDRQPPGVPHDRAD

MXRA8

206

Q9BRK3
LPSHLPRWAPGAREA

MYO9B

2076

Q13459