Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	activin receptor activity	ACVR1B ACVR2B TGFBR2	2.10e-05	9	128	3	GO:0017002
GeneOntologyMolecularFunction	activin binding	ACVR1B ACVR2B TGFBR2	5.43e-05	12	128	3	GO:0048185
GeneOntologyMolecularFunction	tripeptidyl-peptidase activity	TPP2 ACE	1.22e-04	3	128	2	GO:0008240
GeneOntologyMolecularFunction	transketolase activity	TKTL2 TKT	1.22e-04	3	128	2	GO:0004802
GeneOntologyMolecularFunction	transmembrane receptor protein serine/threonine kinase activity	ACVR1B ACVR2B TGFBR2	2.71e-04	20	128	3	GO:0004675
GeneOntologyMolecularFunction	transketolase or transaldolase activity	TKTL2 TKT	4.03e-04	5	128	2	GO:0016744
GeneOntologyMolecularFunction	inhibin binding	ACVR1B ACVR2B	4.03e-04	5	128	2	GO:0034711
GeneOntologyMolecularFunction	IgG receptor activity	FCGR2C FCGR2B	8.38e-04	7	128	2	GO:0019770
GeneOntologyCellularComponent	protein complex involved in cell adhesion	LAMA1 LAMB2 ITGAD ITGB8 PLAUR	3.06e-05	59	128	5	GO:0098636
GeneOntologyCellularComponent	laminin-3 complex	LAMA1 LAMB2	1.11e-04	3	128	2	GO:0005608
GeneOntologyCellularComponent	protein complex involved in cell-matrix adhesion	LAMA1 LAMB2 PLAUR	1.43e-04	17	128	3	GO:0098637
GeneOntologyCellularComponent	cell surface	NRDC MXRA8 ACVR1B ITGAD ACE ITGB8 TGFBR2 FCGR2C CSF1R PTPRK FCGR2B VCAN CORIN PLAUR LY6K LY75 IGSF3	4.43e-04	1111	128	17	GO:0009986
GeneOntologyCellularComponent	activin receptor complex	ACVR1B ACVR2B	5.49e-04	6	128	2	GO:0048179
Domain	PH	ITSN1 SPTBN1 CDC42BPB SPTBN5 OSBPL9 ARHGEF4 SNTA1 VAV1 ARAP1 SPATA13	3.77e-06	229	127	10	PF00169
Domain	PH	ITSN1 SPTBN1 CDC42BPB SPTBN5 OSBPL9 ARHGEF4 SNTA1 VAV1 ARAP1 SPATA13	2.06e-05	278	127	10	SM00233
Domain	PH_DOMAIN	ITSN1 SPTBN1 CDC42BPB SPTBN5 OSBPL9 ARHGEF4 SNTA1 VAV1 ARAP1 SPATA13	2.12e-05	279	127	10	PS50003
Domain	PH_domain	ITSN1 SPTBN1 CDC42BPB SPTBN5 OSBPL9 ARHGEF4 SNTA1 VAV1 ARAP1 SPATA13	2.19e-05	280	127	10	IPR001849
Domain	Spectrin_repeat	SPTBN1 EVPL SPTBN5 PLEC	4.24e-05	29	127	4	IPR002017
Domain	CXorf40	EOLA1 EOLA2	4.59e-05	2	127	2	IPR033615
Domain	SPEC	SPTBN1 EVPL SPTBN5 PLEC	6.33e-05	32	127	4	SM00150
Domain	Spectrin/alpha-actinin	SPTBN1 EVPL SPTBN5 PLEC	6.33e-05	32	127	4	IPR018159
Domain	TGFB_receptor	ACVR1B ACVR2B TGFBR2	6.46e-05	12	127	3	IPR000333
Domain	CH	GAS2L3 SPTBN1 SPTBN5 PLEC VAV1	8.00e-05	65	127	5	SM00033
Domain	CH	GAS2L3 SPTBN1 SPTBN5 PLEC VAV1	1.14e-04	70	127	5	PF00307
Domain	-	GAS2L3 SPTBN1 SPTBN5 PLEC VAV1	1.22e-04	71	127	5	1.10.418.10
Domain	ASCH_domain	EOLA1 EOLA2	1.37e-04	3	127	2	IPR007374
Domain	Transketolase_N	TKTL2 TKT	1.37e-04	3	127	2	PF00456
Domain	Transketolase_N	TKTL2 TKT	1.37e-04	3	127	2	IPR005474
Domain	ASCH	EOLA1 EOLA2	1.37e-04	3	127	2	SM01022
Domain	TRANSKETOLASE_1	TKTL2 TKT	1.37e-04	3	127	2	PS00801
Domain	TRANSKETOLASE_2	TKTL2 TKT	1.37e-04	3	127	2	PS00802
Domain	CH	GAS2L3 SPTBN1 SPTBN5 PLEC VAV1	1.39e-04	73	127	5	PS50021
Domain	CH-domain	GAS2L3 SPTBN1 SPTBN5 PLEC VAV1	1.58e-04	75	127	5	IPR001715
Domain	Transketolase_C	TKTL2 TKT	4.53e-04	5	127	2	IPR033248
Domain	Transketolase_fam	TKTL2 TKT	4.53e-04	5	127	2	IPR033247
Domain	Transketo_C/PFOR_II	TKTL2 TKT	4.53e-04	5	127	2	IPR009014
Domain	Transketolase_C	TKTL2 TKT	4.53e-04	5	127	2	PF02780
Domain	-	TKTL2 TKT	4.53e-04	5	127	2	3.40.50.920
Domain	ACTININ_2	SPTBN1 SPTBN5 PLEC	4.92e-04	23	127	3	PS00020
Domain	ACTININ_1	SPTBN1 SPTBN5 PLEC	4.92e-04	23	127	3	PS00019
Domain	Actinin_actin-bd_CS	SPTBN1 SPTBN5 PLEC	4.92e-04	23	127	3	IPR001589
Domain	IG	TAPBPL MXRA8 UNC5A CSF1R PTPRK FCGR2B PXDNL VCAN IGSF9B IGSF3	6.11e-04	421	127	10	SM00409
Domain	Ig_sub	TAPBPL MXRA8 UNC5A CSF1R PTPRK FCGR2B PXDNL VCAN IGSF9B IGSF3	6.11e-04	421	127	10	IPR003599
Domain	SR	SSC4D LOXL4 CORIN	6.33e-04	25	127	3	SM00202
Domain	PH_dom-like	ITSN1 SPTBN1 CDC42BPB SPTBN5 OSBPL9 ARHGEF4 SNTA1 VAV1 ARAP1 SPATA13	6.69e-04	426	127	10	IPR011993
Domain	-	EVPL PLEC	6.76e-04	6	127	2	3.90.1290.10
Domain	SRCR-like_dom	SSC4D LOXL4 CORIN	7.12e-04	26	127	3	IPR017448
Domain	SRCR_1	SSC4D LOXL4 CORIN	7.12e-04	26	127	3	PS00420
Domain	SRCR_2	SSC4D LOXL4 CORIN	7.12e-04	26	127	3	PS50287
Domain	SRCR	SSC4D LOXL4 CORIN	7.97e-04	27	127	3	IPR001190
Domain	DH_1	ITSN1 ARHGEF4 VAV1 SPATA13	8.91e-04	63	127	4	PS00741
Domain	Plectin	EVPL PLEC	9.42e-04	7	127	2	PF00681
Domain	ACBP	ACBD6 ECI2	9.42e-04	7	127	2	PF00887
Domain	ACB_2	ACBD6 ECI2	9.42e-04	7	127	2	PS51228
Domain	Plectin_repeat	EVPL PLEC	9.42e-04	7	127	2	IPR001101
Domain	ACB_1	ACBD6 ECI2	9.42e-04	7	127	2	PS00880
Domain	PLEC	EVPL PLEC	9.42e-04	7	127	2	SM00250
Domain	EGF	HYAL1 LAMA1 LAMB2 ADAM11 ITGB8 FCGBP VCAN	1.14e-03	235	127	7	SM00181
Domain	RhoGEF	ITSN1 ARHGEF4 VAV1 SPATA13	1.19e-03	68	127	4	SM00325
Domain	6hp_glycosidase	LANCL3 PHKA1	1.25e-03	8	127	2	IPR012341
Domain	Acyl-CoA-binding_protein	ACBD6 ECI2	1.25e-03	8	127	2	IPR000582
Domain	Transketolase-like_Pyr-bd	TKTL2 TKT	1.25e-03	8	127	2	IPR005475
Domain	Transket_pyr	TKTL2 TKT	1.25e-03	8	127	2	SM00861
Domain	Transket_pyr	TKTL2 TKT	1.25e-03	8	127	2	PF02779
Domain	-	LANCL3 PHKA1	1.25e-03	8	127	2	1.50.10.10
Domain	RhoGEF	ITSN1 ARHGEF4 VAV1 SPATA13	1.32e-03	70	127	4	PF00621
Domain	DH_2	ITSN1 ARHGEF4 VAV1 SPATA13	1.32e-03	70	127	4	PS50010
Domain	-	ITSN1 ARHGEF4 VAV1 SPATA13	1.39e-03	71	127	4	1.20.900.10
Domain	DH-domain	ITSN1 ARHGEF4 VAV1 SPATA13	1.39e-03	71	127	4	IPR000219
Domain	-	ITSN1 SPTBN1 CDC42BPB SPTBN5 OSBPL9 ARHGEF4 VAV1 ARAP1 SPATA13	1.42e-03	391	127	9	2.30.29.30
Domain	PH_dom-spectrin-type	SPTBN1 SPTBN5	1.60e-03	9	127	2	IPR001605
Domain	V-set	TAPBPL MXRA8 CSF1R VCAN IGSF9B IGSF3	1.63e-03	184	127	6	PF07686
Domain	IG_LIKE	TAPBPL MXRA8 UNC5A CSF1R PTPRK FCGR2B PXDNL VCAN IGSF9B IGSF3	1.94e-03	491	127	10	PS50835
Domain	Activin_recp	ACVR1B ACVR2B	1.99e-03	10	127	2	PF01064
Domain	Activin_recp	ACVR1B ACVR2B	1.99e-03	10	127	2	IPR000472
Domain	Ig-like_dom	TAPBPL MXRA8 UNC5A CSF1R PTPRK FCGR2B PXDNL VCAN IGSF9B IGSF3	2.31e-03	503	127	10	IPR007110
Domain	GDS_CDC24_CS	ITSN1 ARHGEF4 VAV1	2.35e-03	39	127	3	IPR001331
Domain	Ig_V-set	TAPBPL MXRA8 CSF1R VCAN IGSF9B IGSF3	2.41e-03	199	127	6	IPR013106
Domain	SPRY	RNF135 TRIM62 RNF39 FBXO45	2.94e-03	87	127	4	SM00449
Domain	6-hairpin_glycosidase-like	LANCL3 PHKA1	3.41e-03	13	127	2	IPR008928
Domain	THDP-binding	TKTL2 TKT	3.41e-03	13	127	2	IPR029061
Domain	-	TKTL2 TKT	3.41e-03	13	127	2	3.40.50.970
Domain	-	RMND5B RNF135 FYCO1 CHD5 BRPF1 TRIM62 TRIM8 KDM4A RNF39	3.61e-03	449	127	9	3.30.40.10
Domain	ConA-like_dom	RNF135 LAMA1 PTPRK TRIM62 RNF39 FBXO45	3.87e-03	219	127	6	IPR013320
Domain	SPRY	RNF135 TRIM62 RNF39 FBXO45	3.88e-03	94	127	4	PF00622
Domain	SPRY_dom	RNF135 TRIM62 RNF39 FBXO45	3.88e-03	94	127	4	IPR003877
Domain	B30.2/SPRY	RNF135 TRIM62 RNF39 FBXO45	4.03e-03	95	127	4	IPR001870
Domain	B302_SPRY	RNF135 TRIM62 RNF39 FBXO45	4.03e-03	95	127	4	PS50188
Domain	Znf_RING/FYVE/PHD	RMND5B RNF135 FYCO1 CHD5 BRPF1 TRIM62 TRIM8 KDM4A RNF39	4.16e-03	459	127	9	IPR013083
Domain	PRY	RNF135 TRIM62 RNF39	4.25e-03	48	127	3	SM00589
Domain	PRY	RNF135 TRIM62 RNF39	4.25e-03	48	127	3	IPR006574
Domain	Laminin_N	LAMA1 LAMB2	5.17e-03	16	127	2	IPR008211
Domain	LamNT	LAMA1 LAMB2	5.17e-03	16	127	2	SM00136
Domain	LAMININ_NTER	LAMA1 LAMB2	5.17e-03	16	127	2	PS51117
Domain	Laminin_N	LAMA1 LAMB2	5.17e-03	16	127	2	PF00055
Domain	SH3_1	ITSN1 NOXA1 ARHGEF4 VAV1 SPATA13	5.28e-03	164	127	5	PF00018
Domain	Sushi	VCAN CSMD1 SEZ6	5.32e-03	52	127	3	PF00084
Domain	-	TAPBPL MXRA8 UNC5A CSF1R LRRN4CL PTPRK FCGR2B PXDNL VCAN IGSF9B IGSF3	5.58e-03	663	127	11	2.60.40.10
Domain	Quinoprotein_ADH-like_supfam	WDR36 ERN2 EML5	5.61e-03	53	127	3	IPR011047
Domain	CCP	VCAN CSMD1 SEZ6	5.92e-03	54	127	3	SM00032
Domain	SUSHI	VCAN CSMD1 SEZ6	6.55e-03	56	127	3	PS50923
Pubmed	New genetic associations detected in a host response study to hepatitis B vaccine.	FYCO1 ACE ITGB8 BLM TGFBR2 FCGR2C SSC4D FCGBP FCGR2B PXDNL CCL1 PLAUR LY6K HAL LY75 VAV1	8.41e-08	824	130	16	20237496
Pubmed	Activation of signalling by the activin receptor complex.	ACVR1B ACVR2B TGFBR2	1.01e-06	6	130	3	8622651
Pubmed	Human retroviral gag- and gag-pol-like proteins interact with the transforming growth factor-beta receptor activin receptor-like kinase 1.	ACVR1B ACVR2B TGFBR2	6.01e-06	10	130	3	15611116
Pubmed	Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins.	L3MBTL1 EHMT1 KDM4A	8.24e-06	11	130	3	19144645
Pubmed	Signaling through the TGF beta-activin receptors ALK4/5/7 regulates testis formation and male germ cell development.	ACVR1B ACVR2B TGFBR2	1.10e-05	12	130	3	23342175
Pubmed	Laminin-alpha1 globular domains 3 and 4 induce heterotrimeric G protein binding to alpha-syntrophin's PDZ domain and alter intracellular Ca2+ in muscle.	LAMA1 SNTA1	1.39e-05	2	130	2	15385269
Pubmed	Human IgG Fc receptor (hFcRII; CD32) exists as multiple isoforms in macrophages, lymphocytes and IgG-transporting placental epithelium.	FCGR2C FCGR2B	1.39e-05	2	130	2	2531080
Pubmed	Laminin, a multidomain protein. The A chain has a unique globular domain and homology with the basement membrane proteoglycan and the laminin B chains.	LAMA1 LAMB2	1.39e-05	2	130	2	3182802
Pubmed	C3a and suPAR drive versican V1 expression in tubular cells of focal segmental glomerulosclerosis.	VCAN PLAUR	1.39e-05	2	130	2	30944246
Pubmed	Expression of functional CD32 molecules on human NK cells is determined by an allelic polymorphism of the FcgammaRIIC gene.	FCGR2C FCGR2B	1.39e-05	2	130	2	9516136
Pubmed	Transforming growth factor-beta receptor-associated protein 1 is a Smad4 chaperone.	ACVR1B ACVR2B TGFBR2	1.42e-05	13	130	3	11278302
Pubmed	The deubiquitinase TRABID stabilizes the K29/K48-specific E3 ubiquitin ligase HECTD1.	TPP2 NRDC PHKA1 TRIM62 NEMF ECI2 PPP6R2	1.59e-05	212	130	7	33853758
Pubmed	Impaired plasma membrane localization of ubiquitin ligase complex underlies 3-M syndrome development.	SNPH WDR36 LAMB2 KBTBD7 TBL3 SPTBN5 PDIK1L NEMF LOXL4 PLEC	1.84e-05	496	130	10	31343991
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	IFT172 ITSN1 SPTBN1 CHD9 RIPK4 MDH1 CDC42BPB ITGB8 PTPRK NEMF TRIM8 PLAUR KDM4A ZNF350 PLEC SNTA1	2.56e-05	1285	130	16	35914814
Pubmed	Sorting nexin 6, a novel SNX, interacts with the transforming growth factor-beta family of receptor serine-threonine kinases.	ACVR1B ACVR2B TGFBR2	2.76e-05	16	130	3	11279102
Pubmed	JMJD2A promotes cellular transformation by blocking cellular senescence through transcriptional repression of the tumor suppressor CHD5.	CHD5 KDM4A	4.15e-05	3	130	2	23168260
Pubmed	Identification and characterization of Asef2, a guanine-nucleotide exchange factor specific for Rac1 and Cdc42.	ARHGEF4 SPATA13	4.15e-05	3	130	2	17599059
Pubmed	Laminin-121--recombinant expression and interactions with integrins.	LAMA1 LAMB2	4.15e-05	3	130	2	20566382
Pubmed	Nonallelic homologous recombination of the FCGR2/3 locus results in copy number variation and novel chimeric FCGR2 genes with aberrant functional expression.	FCGR2C FCGR2B	4.15e-05	3	130	2	26133275
Pubmed	The astrocyte-expressed integrin αvβ8 governs blood vessel sprouting in the developing retina.	ITGB8 TGFBR2	4.15e-05	3	130	2	22069187
Pubmed	Genomic pathology of SLE-associated copy-number variation at the FCGR2C/FCGR3B/FCGR2B locus.	FCGR2C FCGR2B	4.15e-05	3	130	2	23261299
Pubmed	Human beta 2 chain of laminin (formerly S chain): cDNA cloning, chromosomal localization, and expression in carcinomas.	LAMA1 LAMB2	4.15e-05	3	130	2	7698745
Pubmed	Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature.	LAMA1 LAMB2	4.15e-05	3	130	2	9049978
Pubmed	Functional Fcgamma receptor polymorphisms are associated with human allergy.	FCGR2C FCGR2B	4.15e-05	3	130	2	24586589
Pubmed	An activin mutant with disrupted ALK4 binding blocks signaling via type II receptors.	ACVR1B ACVR2B	4.15e-05	3	130	2	15123686
Pubmed	Biochemical and Cellular Analysis Reveals Ligand Binding Specificities, a Molecular Basis for Ligand Recognition, and Membrane Association-dependent Activities of Cripto-1 and Cryptic.	ACVR1B ACVR2B TGFBR2	4.73e-05	19	130	3	28126904
Pubmed	EGFR suppresses p53 function by promoting p53 binding to DNA-PKcs: a noncanonical regulatory axis between EGFR and wild-type p53 in glioblastoma.	SPTBN1 TTC7A HAL PLEC	5.10e-05	54	130	4	35474131
Pubmed	Comprehensive analysis of interactions between the Src-associated protein in mitosis of 68 kDa and the human Src-homology 3 proteome.	ITSN1 ARHGEF4 VAV1 SPATA13	5.89e-05	56	130	4	22745667
Pubmed	Hdac4 Interactions in Huntington's Disease Viewed Through the Prism of Multiomics.	SNPH IFT172 SPTBN1 MDH1 PHKA1 PBRM1 NEMF IGSF9B ECI2	7.85e-05	475	130	9	31040226
Pubmed	Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors.	ACVR1B ACVR2B	8.28e-05	4	130	2	14966532
Pubmed	NODAL secreted by male germ cells regulates the proliferation and function of human Sertoli cells from obstructive azoospermia and nonobstructive azoospermia patients.	ACVR1B ACVR2B	8.28e-05	4	130	2	26289399
Pubmed	Characterization of murine CD70 by molecular cloning and mAb.	LAMA1 VAV1	8.28e-05	4	130	2	9620608
Pubmed	TGF-beta receptor mediated telomerase inhibition, telomere shortening and breast cancer cell senescence.	ACVR2B TGFBR2	8.28e-05	4	130	2	27696331
Pubmed	Activin A accelerates the progression of fetal oocytes throughout meiosis and early oogenesis in the mouse.	ACVR1B ACVR2B	8.28e-05	4	130	2	26083127
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMA1 LAMB2	8.28e-05	4	130	2	2099832
Pubmed	ACE and TGFBR1 genes interact in influencing the susceptibility to abdominal aortic aneurysm.	ACE TGFBR2	8.28e-05	4	130	2	18550062
Pubmed	Role of mesenchymal nidogen for epithelial morphogenesis in vitro.	LAMA1 LAMB2	8.28e-05	4	130	2	7925005
Pubmed	Organisation of extracellular matrix proteins laminin and agrin in pericapillary basal laminae in mouse brain.	LAMA1 SNTA1	8.28e-05	4	130	2	32072250
Pubmed	130 kb of DNA sequence reveals two new genes and a regional duplication distal to the human iduronate-2-sulfate sulfatase locus.	EOLA1 EOLA2	8.28e-05	4	130	2	8717057
Pubmed	β8 Integrin Expression and Activation of TGF-β by Intestinal Dendritic Cells Are Determined by Both Tissue Microenvironment and Cell Lineage.	ITGB8 TGFBR2	8.28e-05	4	130	2	27481847
Pubmed	Laminin chain assembly. Specific sequences at the C terminus of the long arm are required for the formation of specific double- and triple-stranded coiled-coil structures.	LAMA1 LAMB2	8.28e-05	4	130	2	8034675
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	LAMA1 LAMB2 ADAM11 VCAN	9.95e-05	64	130	4	22261194
Pubmed	Sequence comparison of human and mouse genes reveals a homologous block structure in the promoter regions.	IMPA1 SPTBN1 LAMB2 EVPL FYCO1 ACVR2B BLM ZNF419 FCGR2C VCAN ANKRD30A KDM4A PLEC CSMD1 SPATA13	1.02e-04	1293	130	15	15342556
Pubmed	Defective retinal vascular endothelial cell development as a consequence of impaired integrin αVβ8-mediated activation of transforming growth factor-β.	ITGB8 TGFBR2	1.38e-04	5	130	2	22279205
Pubmed	The distribution of activin and activin receptors in gestational tissues across human pregnancy and during labour.	ACVR1B ACVR2B	1.38e-04	5	130	2	11969340
Pubmed	Polymorphisms of genes encoding components of the sympathetic nervous system but not the renin-angiotensin system as risk factors for orthostatic hypotension.	ACE GNAS	1.38e-04	5	130	2	11910300
Pubmed	Regulatory T cells promote innate inflammation after skin barrier breach via TGF-β activation.	ITGB8 TGFBR2	1.38e-04	5	130	2	34452925
Pubmed	Compensatory signalling induced in the yolk sac vasculature by deletion of TGFbeta receptors in mice.	ACVR1B TGFBR2	1.38e-04	5	130	2	18029401
Pubmed	Inhibin α-subunit N terminus interacts with activin type IB receptor to disrupt activin signaling.	ACVR1B ACVR2B	1.38e-04	5	130	2	22267736
Pubmed	Copy number variation at the FCGR locus includes FCGR3A, FCGR2C and FCGR3B but not FCGR2A and FCGR2B.	FCGR2C FCGR2B	1.38e-04	5	130	2	19309690
Pubmed	TGFβ Triggers miR-143/145 Transfer From Smooth Muscle Cells to Endothelial Cells, Thereby Modulating Vessel Stabilization.	ITGB8 TGFBR2	1.38e-04	5	130	2	25801897
Pubmed	Asef2 functions as a Cdc42 exchange factor and is stimulated by the release of an autoinhibitory module from a concealed C-terminal activation element.	ARHGEF4 SPATA13	1.38e-04	5	130	2	17145773
Pubmed	Posttranslational modifications and beta/gamma chain associations of human laminin alpha1 and laminin alpha5 chains: purification of laminin-3 from placenta.	LAMA1 LAMB2	1.38e-04	5	130	2	10964500
Pubmed	Inhibin interferes with activin signaling at the level of the activin receptor complex in Chinese hamster ovary cells.	ACVR1B ACVR2B	1.38e-04	5	130	2	9202237
Pubmed	Laminin-10 is crucial for hair morphogenesis.	LAMA1 LAMB2	1.38e-04	5	130	2	12743034
Pubmed	Expression of type I and type IB receptors for activin in midgestation mouse embryos suggests distinct functions in organogenesis.	ACVR1B ACVR2B	1.38e-04	5	130	2	7577669
Pubmed	Truncated activin type II receptors inhibit bioactivity by the formation of heteromeric complexes with activin type I. receptors.	ACVR1B ACVR2B	1.38e-04	5	130	2	8612709
Pubmed	SNPs of Fc-gamma receptor genes and chronic periodontitis.	FCGR2C FCGR2B	1.38e-04	5	130	2	20439936
Pubmed	Copy number, linkage disequilibrium and disease association in the FCGR locus.	FCGR2C FCGR2B	1.38e-04	5	130	2	20508037
Pubmed	Sall1 is a transcriptional regulator defining microglia identity and function.	TGFBR2 CSF1R	1.38e-04	5	130	2	27776109
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	KLHDC2 ITSN1 SPTBN1 NOXA1 CHD9 SIVA1 VARS2 ADAM11 TRMT44 CDCA7 ABCC10 SEZ6	1.91e-04	925	130	12	28986522
Pubmed	Cross-linking of laminin-nidogen complexes by tissue transglutaminase. A novel mechanism for basement membrane stabilization.	LAMA1 LAMB2	2.06e-04	6	130	2	1678389
Pubmed	A Nodal-to-TGFβ cascade exerts biphasic control over cardiopoiesis.	ACVR1B TGFBR2	2.06e-04	6	130	2	22872153
Pubmed	Impaired primary mouse myotube formation on crosslinked type I collagen films is enhanced by laminin and entactin.	LAMA1 LAMB2	2.06e-04	6	130	2	26555376
Pubmed	Effect of basement membrane entactin on epidermal cell attachment and growth.	LAMA1 LAMB2	2.06e-04	6	130	2	3794389
Pubmed	Inhibins are the major activin ligands expressed during early thymocyte development.	ACVR1B ACVR2B	2.06e-04	6	130	2	16477644
Pubmed	Laminin-nidogen complex. Extraction with chelating agents and structural characterization.	LAMA1 LAMB2	2.06e-04	6	130	2	3109910
Pubmed	The adenomatous polyposis coli-associated exchange factors Asef and Asef2 are required for adenoma formation in Apc(Min/+)mice.	ARHGEF4 SPATA13	2.06e-04	6	130	2	19893577
Pubmed	Structural elucidation of full-length nidogen and the laminin-nidogen complex in solution.	LAMA1 LAMB2	2.06e-04	6	130	2	23948589
Pubmed	Entactin: structure and function.	LAMA1 LAMB2	2.06e-04	6	130	2	2119632
Pubmed	Myostatin signals through a transforming growth factor beta-like signaling pathway to block adipogenesis.	ACVR1B ACVR2B	2.06e-04	6	130	2	14517293
Pubmed	An angiotensin-1 converting enzyme polymorphism is associated with allostatic load mediated by C-reactive protein, interleukin-6 and cortisol.	HTR4 ACE	2.06e-04	6	130	2	19081678
Pubmed	Biochemical dissection of Anosmin-1 interaction with FGFR1 and components of the extracellular matrix.	LAMA1 LAMB2	2.06e-04	6	130	2	20874775
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	CDC42BPB TTC7A CHD5 EHMT1 ARHGEF4 ARAP1	2.10e-04	225	130	6	12168954
Pubmed	CITGeneDB: a comprehensive database of human and mouse genes enhancing or suppressing cold-induced thermogenesis validated by perturbation experiments in mice.	NRDC ACVR2B DOCK7 EHMT1 GNAS	2.29e-04	146	130	5	29688375
Pubmed	Interactions of the Antiviral Factor Interferon Gamma-Inducible Protein 16 (IFI16) Mediate Immune Signaling and Herpes Simplex Virus-1 Immunosuppression.	WDR36 TBL3 PBRM1 NUP37 TKT NEMF DOCK7	2.63e-04	332	130	7	25693804
Pubmed	USP45 and Spindly are part of the same complex implicated in cell migration.	TPP2 SPTBN1 LAMB2 PBRM1 VCAN PLEC	2.65e-04	235	130	6	30258100
Pubmed	Circular rapid amplification of cDNA ends for high-throughput extension cloning of partial genes.	ADAM11 FCGBP CSF1R CSMD1	2.85e-04	84	130	4	15203218
Pubmed	An improved method for the synthesis of cellulose membrane-bound peptides with free C termini is useful for PDZ domain binding studies.	PRLHR ACVR2B SCTR SNTA1	2.85e-04	84	130	4	15123239
Pubmed	SB-431542 is a potent and specific inhibitor of transforming growth factor-beta superfamily type I activin receptor-like kinase (ALK) receptors ALK4, ALK5, and ALK7.	ACVR1B TGFBR2	2.88e-04	7	130	2	12065756
Pubmed	Molecular and phenotypic variation in patients with severe Hunter syndrome.	EOLA1 EOLA2	2.88e-04	7	130	2	9147653
Pubmed	Identification of multiple male reproductive tract-specific proteins that regulate sperm migration through the oviduct in mice.	ACE LY6K	2.88e-04	7	130	2	31455729
Pubmed	The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors.	ACVR1B ACVR2B	2.88e-04	7	130	2	11927552
Pubmed	Amotl2 interacts with LL5β, localizes to podosomes and regulates postsynaptic differentiation in muscle.	PLEC SPATA13	2.88e-04	7	130	2	23525008
Pubmed	Histone demethylase JMJD2B functions as a co-factor of estrogen receptor in breast cancer proliferation and mammary gland development.	PBRM1 KDM4A	2.88e-04	7	130	2	21445275
Pubmed	GPI-anchored protein complex, LY6K/TEX101, is required for sperm migration into the oviduct and male fertility in mice.	ACE LY6K	2.88e-04	7	130	2	24501175
Pubmed	Impaired αVβ8 and TGFβ signaling lead to microglial dysmaturation and neuromotor dysfunction.	ITGB8 TGFBR2	2.88e-04	7	130	2	30846482
Pubmed	The deubiquitinating enzyme PSMD14 facilitates tumor growth and chemoresistance through stabilizing the ALK2 receptor in the initiation of BMP6 signaling pathway.	ACVR2B TGFBR2	2.88e-04	7	130	2	31685442
Pubmed	Mammalian homologues of the Drosophila Son of sevenless gene map to murine chromosomes 17 and 12 and to human chromosomes 2 and 14, respectively.	LAMA1 VAV1	2.88e-04	7	130	2	8276400
Pubmed	TRF1 negotiates TTAGGG repeat-associated replication problems by recruiting the BLM helicase and the TPP1/POT1 repressor of ATR signaling.	BLM TINF2	2.88e-04	7	130	2	25344324
Pubmed	Localization of activin and inhibin subunits, receptors and SMADs in the mouse mammary gland.	ACVR1B ACVR2B	2.88e-04	7	130	2	12782414
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA1 LAMB2	2.88e-04	7	130	2	14557481
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	TPP2 SNPH NRDC ITSN1 SPTBN1 MDH1 CDC42BPB TKT VCAN DOCK7 OSBPL9 ARHGEF4 PLEC PPP6R2 SNTA1	3.06e-04	1431	130	15	37142655
Pubmed	A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.	SPTBN1 PBRM1 CHD5	3.33e-04	36	130	3	29089422
Pubmed	Temporal Profiling of Astrocyte Precursors Reveals Parallel Roles for Asef during Development and after Injury.	ARHGEF4 SPATA13	3.83e-04	8	130	2	27881777
Pubmed	Smad7 inhibits transforming growth factor-beta family type i receptors through two distinct modes of interaction.	ACVR1B ACVR2B	3.83e-04	8	130	2	20663871
Pubmed	Growth differentiation factor 11 signals through the transforming growth factor-beta receptor ALK5 to regionalize the anterior-posterior axis.	ACVR1B ACVR2B	3.83e-04	8	130	2	16845371
Pubmed	Identification of human activin and TGF beta type I receptors that form heteromeric kinase complexes with type II receptors.	ACVR2B TGFBR2	3.83e-04	8	130	2	8242742
Pubmed	Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor.	LAMA1 VAV1	3.83e-04	8	130	2	8405064
Pubmed	Activation of Rac GTPase by p75 is necessary for c-jun N-terminal kinase-mediated apoptosis.	ITSN1 ARHGEF4 VAV1	3.91e-04	38	130	3	11756498
Interaction	CRIPTO interactions	RMND5B ACVR1B ACVR2B TGFBR2 VCAN FBXO45	4.40e-06	69	125	6	int:CRIPTO
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ITSN1 SPTBN1 OSBPL9 ARHGEF4 VAV1 ARAP1 SPATA13	8.11e-05	206	91	7	682
GeneFamily	Type 2 receptor serine/threonine kinases	ACVR2B TGFBR2	2.48e-04	5	91	2	346
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	ITSN1 ARHGEF4 VAV1 SPATA13	3.41e-04	66	91	4	722
GeneFamily	WD repeat domain containing\|UTPB complex	WDR36 TBL3	3.71e-04	6	91	2	1225
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN1 SPTBN5	5.18e-04	7	91	2	1113
GeneFamily	EF-hand domain containing\|Plakins	EVPL PLEC	6.88e-04	8	91	2	939
GeneFamily	Ankyrin repeat domain containing	RIPK4 ACBD6 ASB11 ANKRD30A EHMT1 ARAP1	1.40e-03	242	91	6	403
GeneFamily	Laminin subunits	LAMA1 LAMB2	1.60e-03	12	91	2	626
GeneFamily	Immunoglobulin like domain containing	CSF1R PTPRK FCGR2B IGSF9B IGSF3	2.92e-03	193	91	5	594
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	VCAN CSMD1 SEZ6	2.97e-03	57	91	3	1179
GeneFamily	ADAM metallopeptidase domain containing\|CD molecules	ITGAD ACE FCGR2C CSF1R FCGR2B PLAUR LY75	3.73e-03	394	91	7	471
Coexpression	GSE11961_FOLLICULAR_BCELL_VS_MEMORY_BCELL_DAY7_DN	KLHDC2 CHD9 MDH1 KBTBD7 FCGR2B PDIK1L DOCK7 GNAS	6.53e-06	200	128	8	M9339
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_anti-infl-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DAGLB TTC7A FCGR2C FCGBP CSF1R PLAUR PLEC ARAP1	1.28e-07	200	129	8	74ceebee9af63f8b3ec5857eff1b662752bc3862
ToppCell	droplet-Lung-nan-21m-Myeloid-Intermediate_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAGLB NIBAN1 ACE TTC7A CSF1R PLAUR SPATA13	4.38e-07	160	129	7	0b8151037b28f52a21918856a1e9336e8d5edb90
ToppCell	droplet-Lung-nan-21m-Myeloid-intermediate_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAGLB NIBAN1 ACE TTC7A CSF1R PLAUR SPATA13	4.38e-07	160	129	7	4738d0c73d8c3508e5b5beb6c61e0ad551d9b949
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-A\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FCGR2C FCGBP FCGR2B VCAN PLAUR AVPI1 PLEC	1.12e-06	184	129	7	a902109b04a94770f5f6db5ddc372049f2921d38
ToppCell	AT1-AT2_cells-SSc-ILD_02\|World / lung cells shred on cell class, cell subclass, sample id	UNC13D SCTR CORIN ARHGEF4 HAL IGSF3	6.09e-06	155	129	6	010e45ef4b505bf419ea41e4d1619521d1c78319
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 SIVA1 ACBD6 BLM TRMT44 SEZ6	7.04e-06	159	129	6	7ed659163f45e0c4df4782997c0786900c8186c8
ToppCell	droplet-Marrow-BM-30m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTBN1 ACVR1B ACE CSF1R ZSWIM4 SNTA1	8.41e-06	164	129	6	b77995958c938e10a526118f75d78cee72e0b207
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LANCL3 NOXA1 ACVR1B FCGBP CSMD1 RNF39	9.98e-06	169	129	6	30141f76e9bfc2b4586429857c72dbc85ba65cc9
ToppCell	10x5'-bone_marrow-Myeloid_Mac-Intestinal_macrophages\|bone_marrow / Manually curated celltypes from each tissue	GAS2L3 ACE SPTBN5 SSC4D FCGBP CSF1R	1.18e-05	174	129	6	0746344d62aa7ab77c378e9d5a9f9238e741a76b
ToppCell	P28-Epithelial-epithelial_progenitor_cell-epithelial_unknown_3\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	NIBAN1 ADAM11 ITGB8 VCAN CSMD1 SPATA13	1.43e-05	180	129	6	1e819c5c87704ec6535dfeaae56561895e239d07
ToppCell	T_cells-Resident_memory_CD8+_T_cells\|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis	SNPH NOXA1 ACVR1B ECI2 PATJ SNTA1	1.52e-05	182	129	6	111d434b89902ec11fb07f41b8ee1a98f3991b61
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB NOXA1 SYT9 UNC13D RIPK4 PATJ	1.57e-05	183	129	6	ff6dde877659cde9daa3263db0932c9c9ef1adac
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland-SMG_Duct\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FCGBP L3MBTL1 LOXL4 ZSWIM4 SNTA1	1.58e-05	108	129	5	9c7f3e25facfb54ef0be45044999bc36438bbea0
ToppCell	Parenchymal-10x5prime-Epithelial-Epi_submucosal-gland\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	FCGBP L3MBTL1 LOXL4 ZSWIM4 SNTA1	1.58e-05	108	129	5	75d635fc5bb004418db2e1328c24d96b718f10b1
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l30\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	GAS2L3 ADAM11 CHD5 CSMD1 SNTA1 IGSF3	1.77e-05	187	129	6	6f7f293c9cf35261e0e3614e46ec1fb00a701b63
ToppCell	PCW_13-14-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LANCL3 NIBAN1 SFTPB EVPL FCGBP PATJ	1.83e-05	188	129	6	0d86044bc340e3efb90d0022dd299873639d831c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA1 ITGB8 SSC4D FCGBP SCTR PATJ	1.94e-05	190	129	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	Epithelial-club_cell\|World / Lineage, Cell type, age group and donor	NIBAN1 SFTPB ERN2 PTPRK PATJ RNF39	2.12e-05	193	129	6	2bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NIBAN1 LAMA1 EVPL ASB11 PLAUR CSMD1	2.24e-05	195	129	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	NIBAN1 LAMA1 EVPL ASB11 PLAUR CSMD1	2.24e-05	195	129	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	LPS_IL1RA_TNF\|World / Treatment groups by lineage, cell group, cell type	SFTPB MXRA8 CHD9 VARS2 PXDNL VCAN	2.38e-05	197	129	6	0a6550dce156fc81f15b1e7830d331ca50d87d06
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_INF-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TTC7A FCGR2C CSF1R PLAUR AVPI1 PLEC	2.38e-05	197	129	6	8c24ffcd417da42fa9bcbe6bd0325360e537303f
ToppCell	LPS_only-Hematopoietic_Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|LPS_only / Treatment groups by lineage, cell group, cell type	FCGR2C CSF1R TKT VCAN PLAUR ARAP1	2.44e-05	198	129	6	2985c80e656e483866c696fa08c38af90311cd66
ToppCell	LPS_only-Hematopoietic_Myeloid-Monocytes,_Macrophages\|LPS_only / Treatment groups by lineage, cell group, cell type	FCGR2C CSF1R TKT VCAN PLAUR ARAP1	2.44e-05	198	129	6	5d48539999d7a17f4165f612bf68be26c085e501
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FCGR2C FCGBP FCGR2B VCAN PLAUR AVPI1	2.44e-05	198	129	6	06e13ba14bda79e01a757ceb9e88de133053df61
ToppCell	356C-Fibroblasts-Fibroblast-F-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPTBN1 WNT2B MXRA8 TGFBR2 LRRN4CL VCAN	2.51e-05	199	129	6	beca4c7eb29ac771fd37f30cd23d4dce4afcfff8
ToppCell	356C-Fibroblasts-Fibroblast-F\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	SPTBN1 WNT2B MXRA8 TGFBR2 LRRN4CL VCAN	2.51e-05	199	129	6	cd3ab9a75b40e0d417d53b3d8756fc9bed30ac83
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	SPTBN1 LAMB2 UNC13D ACE GNAS PLEC	2.51e-05	199	129	6	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	Parenchymal-10x5prime-Immune_Myeloid-Macrophage_other-Macro_AW_CX3CR1\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	MDH1 FCGBP CSF1R FCGR2B PLAUR BTBD19	2.51e-05	199	129	6	8a7bccf76fdf0b46854750a0a6a5eade0e14e515
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	WDR36 ITSN1 ITGB8 VCAN SLC25A28 SPATA13	2.51e-05	199	129	6	8b86c69aaf60feff53aa782559cfece7342a23de
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	SFTPB NOXA1 UNC13D RIPK4 EML5 PATJ	2.59e-05	200	129	6	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	Influenza\|World / Disease, condition lineage and cell class	NIBAN1 TKT VCAN TRIM8 PLAUR PLEC	2.59e-05	200	129	6	df996c35907a1c9194b9e2ca30e81f520ca067f0
ToppCell	LPS-antiTNF-Epithelial_alveolar-Mes-Like-AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	RIPK4 ADAM11 TTC4 SPTBN5 SCTR	3.19e-05	125	129	5	5626eb77e542fcc87cd1fdf65f8623f3249ff9db
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nfib-Inhibitory_Neuron.Gad1Gad2.Nfib-Satb1_(Supramammillary_Nucleus_(SuM))\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CHRNA2 SPTBN5 CORIN RNF39	4.05e-05	66	129	4	f7d1d272ae723d8100b8c252b3d894dae5297fe4
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nfib\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CHRNA2 SPTBN5 CORIN RNF39	4.05e-05	66	129	4	2180e189dad1347ad77733ea95a934d70be97ee4
ToppCell	Substantia_nigra-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Nfib-Inhibitory_Neuron.Gad1Gad2.Nfib-Satb1_(Supramammillary_Nucleus_(SuM))-\|Substantia_nigra / BrainAtlas - Mouse McCarroll V32	CHRNA2 SPTBN5 CORIN RNF39	4.05e-05	66	129	4	412c95c708344fd1726351389bb8a3d376f54fe4
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte\|GW09 / Sample Type, Dataset, Time_group, and Cell type.	SNPH HYAL1 LAMA1 TGFBR2 ARHGEF4	5.87e-05	142	129	5	85e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell	TCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3\|TCGA-Brain / Sample_Type by Project: Shred V9	TPP2 ACVR2B VCAN KDM4A RNF39	7.37e-05	149	129	5	768877bade04ca0321593b8470b5011ad8270431
ToppCell	18-Airway-Epithelial-Goblet-like_secretory\|Airway / Age, Tissue, Lineage and Cell class	ERN2 ACE FCGBP L3MBTL1 LY6K	8.35e-05	153	129	5	14a60220e169ce642771636de982a7b02e5b2608
ToppCell	IIH-CD8-exh_CD4\|IIH / Condition, Cell_class and T cell subcluster	TMEM120B IFT172 SPTBN1 C1orf167 LOXL4	8.61e-05	154	129	5	a2f51a3c5455fe2483e438375ea856afce8262fe
ToppCell	normal_Pleural_Fluid-Myeloid_cells-Monocytes\|Myeloid_cells / Location, Cell class and cell subclass	MXRA8 TRIM62 PLAUR AVPI1 BTBD19	8.88e-05	155	129	5	85eb60d285b8bfc095c341ae90c0e3b7e7dca9c1
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	IFT172 UNC13D TGFBR2 VCAN CSMD1	9.72e-05	158	129	5	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	368C-Myeloid-Macrophage-SPP1+_Macrophage_4\|368C / Donor, Lineage, Cell class and subclass (all cells)	GAS2L3 ADAM11 TTC7A CSF1R FCGR2B	9.72e-05	158	129	5	f9cfb110342be3c91aba9914805332f22ba89101
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Macrophage / Donor, Lineage, Cell class and subclass (all cells)	HYAL1 EML5 PTPRK SCTR IGSF3	1.09e-04	162	129	5	2259e9536147e9cdee772e3a30ba7d104573262c
ToppCell	10x5'-Lung-Lymphocytic_T_CD8-Tnaive/CM_CD8\|Lung / Manually curated celltypes from each tissue	SPTBN1 RIPK4 C1orf167 L3MBTL1 ZNF350	1.12e-04	163	129	5	c8e4440d1a857e4da83002303940dd42b273c92e
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAGLB NIBAN1 TTC7A CSF1R PLAUR	1.16e-04	164	129	5	cd0794f84dfd346807e2d803723718b7f22e9232
ToppCell	droplet-Lung-21m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DAGLB NIBAN1 TTC7A CSF1R PLAUR	1.16e-04	164	129	5	12251a49fd4af32d4edb58046245548c260cf04b
ToppCell	droplet-Fat-Scat-18m-Myeloid-monocyte\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF1R FCGR2B VCAN PLAUR VAV1	1.19e-04	165	129	5	015f8f408d7fd17292defe63fa02b16eed642dfb
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF1R FCGR2B VCAN HAL VAV1	1.23e-04	166	129	5	bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCell	LPS-antiTNF-Endothelial-Mes-Like-Alv_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SNPH TAPBPL RWDD2B TBL3 RERGL	1.23e-04	166	129	5	94a00edf66d54bc5f7343daea700ca26cf38fd90
ToppCell	facs-Lung-EPCAM-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CSF1R FCGR2B VCAN HAL VAV1	1.23e-04	166	129	5	433128b7d964b32faa0bf437a02facc819ab1405
ToppCell	356C-Myeloid-Macrophage-FABP4+_Macrophage\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	HYAL1 EML5 PTPRK SCTR IGSF3	1.23e-04	166	129	5	89e2b8453180983533faccb4275867861876d7ee
ToppCell	droplet-Liver-LIVER_HEPATOCYTES-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LANCL3 NOXA1 ACVR1B CSMD1 RNF39	1.26e-04	167	129	5	cf6206c506715cd846799c62cf7c06e3fa99f7af
ToppCell	droplet-Fat-Bat-18m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 DND1 KBTBD7 HAL PPP6R2	1.30e-04	168	129	5	6fddc957a0503455d8c165862b5eb8e5fdb8a510
ToppCell	Children_(3_yrs)-Immune-enucleated_erythrocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SNPH ERN2 FCGR2B TRIM62 IGSF9B	1.30e-04	168	129	5	8f0c4dfad9f6fed9dcc31795abfe77758ceb46a1
ToppCell	P28-Epithelial-airway_epithelial_cell-ciliated_cell_of_airway\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	UNC13D EVPL BLM CSF1R PATJ	1.30e-04	168	129	5	8c8dbdbc7053f34e4ca0c5067af502fbea109fc1
ToppCell	PND28-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	VARS2 BLM TTC7A PPP6R2 ARAP1	1.30e-04	168	129	5	27cdf5cfa1d906868cfd60fdfab3cd51f3b3602f
ToppCell	droplet-Fat-Bat-18m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 DND1 KBTBD7 HAL PPP6R2	1.30e-04	168	129	5	794035cb63353a7d02fd9939deb5b4d075c9d95a
ToppCell	droplet-Fat-Bat-18m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 DND1 KBTBD7 HAL PPP6R2	1.30e-04	168	129	5	1e23b634f96e88b976a523ca1f3fc08f6fe9b239
ToppCell	E16.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 FYCO1 TRIM62 VAV1 ABCC10	1.33e-04	169	129	5	305cedbd97059029d7d2a248a8a4b6cfe281aa54
ToppCell	facs-Heart-LV-18m-Myeloid\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAGLB GAS2L3 CSF1R FCGR2B VAV1	1.37e-04	170	129	5	4eaa22040e475100061475123aefa32b56481464
ToppCell	facs-Heart-LV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAGLB GAS2L3 CSF1R FCGR2B VAV1	1.37e-04	170	129	5	60041b2e57e958f300a5bc76851705c8baf297c2
ToppCell	facs-Heart-LV-18m-Myeloid-monocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DAGLB GAS2L3 CSF1R FCGR2B VAV1	1.37e-04	170	129	5	793dde64f5517538b66de5f461a445c4ad6dd7b3
ToppCell	10x5'-Liver-Myeloid_Mac-Intermediate_macrophages\|Liver / Manually curated celltypes from each tissue	CHRNA2 ITGB8 VCAN PLAUR AVPI1	1.41e-04	171	129	5	25e0333743affdb662223fb5220b8a61fa02ad9f
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	EOLA2 TRMT44 CDCA7 DOCK7 FBXO45	1.49e-04	173	129	5	b9dee61973559e8c2fef3f2dafd43475b386befb
ToppCell	droplet-Pancreas-Exocrine-21m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	LAMA1 UNC13D ACVR1B FCGBP SCTR	1.53e-04	174	129	5	a0ccda8fd6f55251cdeff24cf66e72e4a31d2104
ToppCell	droplet-Kidney-KIDNEY-30m-Mesenchymal-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SFTPB FCGBP PTPRK PATJ BTBD19	1.57e-04	175	129	5	31f0fb2e47e357dbf9c15436b7df85b3c370ded7
ToppCell	3'-Parenchyma_lung-Epithelial-Epithelial_transtional-epithelial_cell_of_lung-Transitional_Club-AT2-Transitional_Club-AT2_L.0.4.1.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SFTPB HYAL1 LAMB2 PHKA1 FCGBP	1.57e-04	175	129	5	dbd9dac129fb6ae5f55e7b96d04b37585458dc4a
ToppCell	droplet-Liver-LIVER_NPC-30m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EVPL TBC1D13 FCGBP CSMD1 RNF39	1.57e-04	175	129	5	f7cd2ef79d91d64976fcdb5f1e7343b24ba27456
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_GGH\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PRLHR CHRNA2 SCTR CCL1 SEZ6	1.61e-04	176	129	5	23f930dac5247ea6d4124da33933d61ad6e089af
ToppCell	390C-Lymphocytic-CD4_T-cell-CD4+_Effector_T_cell-2\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NIBAN1 CDCA7 DOCK7 PATJ FBXO45	1.61e-04	176	129	5	437cfc5e06416bb0fc76d1f9dc106f74e279e880
ToppCell	droplet-Marrow-BM-1m-Lymphocytic-plasma_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAD TGFBR2 CSF1R AVPI1 SNTA1	1.65e-04	177	129	5	26bad614560609d318bfc9c235a698bca4e1c22c
ToppCell	TCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-1\|TCGA-Liver / Sample_Type by Project: Shred V9	UNC13D ITGB8 UNC5A SCTR ZSWIM4	1.70e-04	178	129	5	51c59dabf2d7aef1b1964f6f766d5ec07ef90f5a
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NIBAN1 SFTPB ERN2 PTPRK PATJ	1.70e-04	178	129	5	f5ed4a6e3eb8056b1be1fb311021710c95bdf888
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NIBAN1 SFTPB PTPRK AVPI1 PATJ	1.74e-04	179	129	5	815b959ce8721c5ded70c0ca6e318dafc691746e
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NIBAN1 SFTPB ERN2 PATJ RNF39	1.79e-04	180	129	5	b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTPB TKT SCTR HAL PATJ	1.83e-04	181	129	5	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GAS2L3 ADAM11 FCGR2B CHD5 CSMD1	1.88e-04	182	129	5	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 TKT PLAUR LY75 VAV1	1.88e-04	182	129	5	94d061b7b5ebbfc564c644bc8b2d52341927145d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	SFTPB PTPRK SCTR CORIN PATJ	1.93e-04	183	129	5	6847c1252d6bb105524f812658112517fd351eab
ToppCell	COPD-Epithelial-ATII\|World / Disease state, Lineage and Cell class	SFTPB PTPRK SCTR PATJ IGSF3	1.93e-04	183	129	5	8e9aab4eeec2e282c2cab9bfca6dbf40d660c7b9
ToppCell	PCW_07-8.5-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PRLHR SYT9 UNC5A EML5 CHD5	1.98e-04	184	129	5	571136c832cb8c08457744152231537aa8e8abd7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-AT2_Progenitor\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB NOXA1 SYT9 EML5 PATJ	1.98e-04	184	129	5	7cc5796557379c3d1db078c1aeda40659c6e401c
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB NOXA1 UNC13D RIPK4 PATJ	2.03e-04	185	129	5	c82eab551f65ecebe6db908eda9f9eb3414693c7
ToppCell	21-Trachea-Epithelial-Goblet-like_secretory\|Trachea / Age, Tissue, Lineage and Cell class	SFTPB ERN2 ACE FCGBP ASB11	2.08e-04	186	129	5	f8cddad28896f0edf10a8645fa49a011b22b120d
ToppCell	LPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB SYT9 RIPK4 EML5 PATJ	2.08e-04	186	129	5	4e94158db52df41d71e67b02b9895a358eebee0f
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB NOXA1 UNC13D RIPK4 PATJ	2.08e-04	186	129	5	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	10x5'-Liver-Myeloid_Dendritic-DC2\|Liver / Manually curated celltypes from each tissue	GAS2L3 CSF1R FCGR2B PXDNL PLAUR	2.08e-04	186	129	5	92ef569c8f864d3abaa087cd3ce0366e8f9f50c2
ToppCell	PCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	LANCL3 SFTPB EVPL FCGBP PATJ	2.08e-04	186	129	5	bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SFTPB TKT SCTR HAL PATJ	2.08e-04	186	129	5	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	PCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	SFTPB LAMA1 EVPL PHKA1 PATJ	2.13e-04	187	129	5	db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCell	PBMC-Mild-cDC_5\|Mild / Compartment, Disease Groups and Clusters	LAMA1 PLAUR AVPI1 ZNF350 LY6K	2.13e-04	187	129	5	0afef5baf3752314dbfb024790347d5e51f9b84b
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SFTPB NOXA1 SYT9 UNC13D PATJ	2.13e-04	187	129	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA1 ITGB8 FCGBP SCTR PATJ	2.13e-04	187	129	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 BLM FCGBP CSF1R VAV1	2.13e-04	187	129	5	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	10x_5'_v1-Non-neoplastic-Myeloid-Mono\|10x_5'_v1 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ITSN1 TKT VCAN PLAUR HAL	2.19e-04	188	129	5	fbf176b48b89c234e4e1e64739afc836bed78a96
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 RERGL CHD5 SCTR CSMD1	2.24e-04	189	129	5	7fbe855bfdb47d35e040b04a80fe4b729a3764e8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell-\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 RERGL CHD5 SCTR CSMD1	2.24e-04	189	129	5	06b35abecd29f902cf251fcc1f6ad33db7ab08a2
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	GAS2L3 ITSN1 FCGBP CSF1R FCGR2B	2.24e-04	189	129	5	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	LAMA1 ITGB8 FCGBP SCTR PATJ	2.30e-04	190	129	5	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
Disease	plexin-B2 measurement	FCGR2C FCGR2B PPP6R2	5.02e-06	9	117	3	EFO_0021867
Disease	mean platelet volume	DAGLB NIBAN1 TMEM120B NRDC SPTBN1 CHD9 UNC13D CDC42BPB DOCK7 GNAS PLEC LY75 VAV1 ARAP1	5.36e-05	1020	117	14	EFO_0004584
Disease	serum gamma-glutamyl transferase measurement	SFTPB IFT172 RNF135 CHD9 RWDD2B CDC42BPB FCGR2C PBRM1 FCGR2B CSMD1 PPP6R2 SLC25A28 SPATA13	7.06e-05	914	117	13	EFO_0004532
Disease	platelet measurement	TMEM120B CHD9 PBRM1 DOCK7 PLEC LY75 VAV1	2.69e-04	315	117	7	EFO_0005036
Disease	nephrosis (implicated_via_orthology)	LAMB2 ACE	3.23e-04	7	117	2	DOID:2527 (implicated_via_orthology)
Disease	lung cancer (is_marker_for)	SFTPB CSF1R KDM4A	5.00e-04	39	117	3	DOID:1324 (is_marker_for)
Disease	malaria (implicated_via_orthology)	FCGR2C FCGR2B	5.51e-04	9	117	2	DOID:12365 (implicated_via_orthology)
Disease	Antihypertensive use measurement	HTR4 WNT2B RERGL PXDNL TKT ABCC10	6.75e-04	265	117	6	EFO_0009927
Disease	Marfan syndrome (implicated_via_orthology)	ACVR2B TGFBR2	6.87e-04	10	117	2	DOID:14323 (implicated_via_orthology)
Disease	Prostatic Neoplasms	ITSN1 LAMB2 UNC13D ACE TGFBR2 PTPRK BRPF1 PLAUR PATJ	7.96e-04	616	117	9	C0033578
Disease	Malignant neoplasm of prostate	ITSN1 LAMB2 UNC13D ACE TGFBR2 PTPRK BRPF1 PLAUR PATJ	7.96e-04	616	117	9	C0376358
Disease	urokinase-type plasminogen activator measurement	PLAUR LY75	8.38e-04	11	117	2	EFO_0010803
Disease	immature platelet fraction	TMEM120B GNAS PLEC VAV1	1.12e-03	114	117	4	EFO_0009187
Disease	toxic shock syndrome (is_implicated_in)	SFTPB ACE	1.18e-03	13	117	2	DOID:14115 (is_implicated_in)
Disease	Acute Cerebrovascular Accidents	HTR4 WNT2B ACE	1.30e-03	54	117	3	C0751956
Disease	urokinase plasminogen activator surface receptor measurement	PLAUR LY75	1.38e-03	14	117	2	EFO_0010932
Disease	asthma, body mass index	UNC13D ITGB8	1.38e-03	14	117	2	EFO_0004340, MONDO_0004979
Disease	asthma, Eczema, allergic rhinitis	WDR36 ITGB8 PTPRK FBXO45	1.40e-03	121	117	4	EFO_0005854, HP_0000964, MONDO_0004979
Disease	hypertension (is_implicated_in)	PRLHR ACE CORIN GNAS	1.40e-03	121	117	4	DOID:10763 (is_implicated_in)
Disease	Malignant Neoplasms	BLM CSF1R PLAUR GNAS	1.72e-03	128	117	4	C0006826
Disease	mood instability measurement	TMEM120B HTR4 LAMB2 CSMD1	1.72e-03	128	117	4	EFO_0008475
Disease	pneumonia (is_implicated_in)	SFTPB ACE	1.80e-03	16	117	2	DOID:552 (is_implicated_in)
Disease	Pre-Eclampsia	ACE CORIN	1.80e-03	16	117	2	C0032914
Disease	Cerebrovascular accident	HTR4 WNT2B ACE	1.94e-03	62	117	3	C0038454
Disease	chronic obstructive pulmonary disease (is_implicated_in)	SFTPB ACE CCL1	2.03e-03	63	117	3	DOID:3083 (is_implicated_in)
Disease	low affinity immunoglobulin gamma Fc region receptor II-a measurement	FCGR2C FCGR2B	2.04e-03	17	117	2	EFO_0021969
Disease	neutrophil percentage of granulocytes	WDR36 HTR4 ITGB8 PLAUR RNF39	2.19e-03	228	117	5	EFO_0007994
Disease	Tachycardia	HTR4 GNAS	2.29e-03	18	117	2	C0039231
Disease	Tachyarrhythmia	HTR4 GNAS	2.29e-03	18	117	2	C0080203
Disease	lung non-small cell carcinoma (is_implicated_in)	SFTPB ACVR1B PBRM1 CSF1R	2.32e-03	139	117	4	DOID:3908 (is_implicated_in)
Disease	red blood cell density measurement	ITSN1 SPTBN1 ACVR1B FCGR2C PBRM1 FCGR2B KDM4A PLEC LY75 SLC25A28	2.67e-03	880	117	10	EFO_0007978
Disease	Schizophrenia	HTR4 LAMA1 MDH1 ACE PBRM1 EML5 PDIK1L GNAS CSMD1 FBXO45	2.74e-03	883	117	10	C0036341
Disease	emphysema imaging measurement	PTPRK PDIK1L LOXL4 CSMD1	2.77e-03	146	117	4	EFO_0007626
Disease	gastric ulcer	LY6K GNAS	3.12e-03	21	117	2	EFO_0009454
Disease	respiratory symptom measurement, COVID-19	FYCO1 KDM4A CSMD1	3.21e-03	74	117	3	EFO_0007939, MONDO_0100096
Disease	serum non-albumin protein measurement	TPP2 CDC42BPB FCGR2C FCGR2B FBXO45 ARAP1	3.23e-03	361	117	6	EFO_0004568
Disease	nephrosis (biomarker_via_orthology)	ACE CCL1	3.42e-03	22	117	2	DOID:2527 (biomarker_via_orthology)
Disease	Liver Cirrhosis, Experimental	RMND5B MDH1 TGFBR2 CSF1R DOCK7 HAL RNF39 VAV1 SEZ6	3.75e-03	774	117	9	C0023893
Disease	myocardial infarction (biomarker_via_orthology)	ACE TGFBR2 VCAN PLAUR	3.84e-03	160	117	4	DOID:5844 (biomarker_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
EACALDTVGWVQRHR	CCL1	71	P22362
NCTIAVHIAHRDWEG	EOLA1	36	Q8TE69
NCTIAVHIAHRDWEG	EOLA2	36	Q96DE9
VHIAHRDWEGDACRE	EOLA2	41	Q96DE9
WCEVVRDTGVLRAQH	C1orf167	1031	Q5SNV9
LIGNDTRVCQEDSHW	CSMD1	2891	Q96PZ7
AGEDCVVIIWHENGQ	VCAN	3261	P13611
LGSIEWACLVVDEAH	CHD5	836	Q8TDI0
PADGREVVCHASAWD	ACE	351	P12821
WEIARRCNSGGVHEE	ACVR1B	411	P36896
EFQEGETIVLRCHSW	FCGR2B	141	P31994
DRQCQVLWGHAAADR	ADAM11	551	O75078
ISDGSVVCAEALWDH	ARHGEF4	191	Q9NR80
ALHWACVNGHEEVVT	ANKRD30A	76	Q9BXX3
AEERAQIIWECAGDH	AVPI1	51	Q5T686
QIIWECAGDHRVAEA	AVPI1	56	Q5T686
VVEEEDRWACAGHVA	CHRNA2	416	Q15822
VGVRVEAFDCQEWAE	ACOT12	261	Q8WYK0
DCWADRSPLHEAAAQ	ASB11	61	Q8WXH4
NVKDEEGRALLHWAC	ACBD6	186	Q9BR61
VDVLCEVDQAWLEGH	NOXA1	426	Q86UR1
EVDQAWLEGHCDGRI	NOXA1	431	Q86UR1
EIQWETRLFHEDGEC	OSBPL9	706	Q96SU4
EVLAGCVAAVAWISH	ABCC10	101	Q5T3U5
HIVCIERLWEDSAGE	PBRM1	976	Q86U86
LEVLHQGQWGTVCDD	LOXL4	46	Q96JB6
VRIAAEEGRAVVHWC	LRRN4CL	91	Q8ND94
SQRTDEGDNRVWCHV	LY6K	31	Q17RY6
LFKVDESCVWRHQGE	NEMF	656	O60524
AEERWLGDTEANHCL	FYCO1	1166	Q9BQS8
CATVVGDDQWGHLQL	PHKA1	121	P46020
LEAGGCAVVRDNWHE	ERN2	811	Q76MJ5
AAKAICDHVRDIWFG	MDH1	246	P40925
EFQEGETIVLRCHSW	FCGR2C	141	P31995
VWTVAQLGDLVCSDH	L3MBTL1	791	Q9Y468
WVGAREISHDACFAQ	OR51G2	91	Q8NGK0
LHVDSICDWDSGEVQ	EVPL	416	Q92817
HRVTDCVRAVWQNEG	SLC25A28	206	Q96A46
DRWVHVSCAVAILEA	KDM4A	791	O75164
GETIERENELVHWCH	LANCL3	281	Q6ZV70
WEEAERFCQALGAHL	LY75	671	O60449
HACFGDWDRVVQDLA	LAMB2	1191	P55268
ERTVCHVAVQWLEAA	KBTBD7	236	Q8WVZ9
DVLVNGDCQWITALH	CDC42BPB	126	Q9Y5S2
DHTCRIWNLEGVQTA	NUP37	146	Q8NFH4
QELHRWDECIAVAEA	IFT172	716	Q9UG01
VQWQCDAVLRGEQGH	ITGAD	501	Q13349
LQAAVCESHIGWRKE	ITGB8	261	P26012
LEEHAVEWLCEADGN	PXDNL	431	A1KZ92
IVEAWKCHALRRGDE	BTBD19	251	C9JJ37
LNAIEWRCVIIDEAH	CHD9	986	Q3L8U1
GHTDRCDEAQVLQVW	CSF1R	436	P07333
EGQYECHVTEWVRAV	IGSF3	506	O75054
CHVTEWVRAVDGEWQ	IGSF3	511	O75054
VHVRGEWLAVPCQDA	HAL	6	P42357
RFVIDEAHCVSQWGH	BLM	791	P54132
HEELALQWVVCSGSV	DOCK7	986	Q96N67
HGDENSEVWRSLCAR	FBXO45	71	P0C2W1
AAWVADGVQCDRTVV	DAGLB	116	Q8NCG7
ACQAAGVVIEDWRAQ	FCGBP	4331	Q9Y6R7
ANFLHWCRDIGVDET	GAS2L3	126	Q86XJ1
DRLEWIQAHVQCEGL	ITSN1	1431	Q15811
HVLRDAVECGGQWES	HTR4	356	Q13639
VAHCFEGRENAAVWK	CORIN	841	Q9Y5Q5
VNDSVWVHGPIDDRC	ERVK-21	126	P61565
EGQSHLCGEQVAVEW	DND1	201	Q8IYX4
WHTACASDEGEVIVF	KLHDC2	321	Q9Y2U9
QWCLERHGVDVDVSV	HYAL1	41	Q12794
HAVNAEECNVLQGRW	ECI2	361	O75521
GIWSRHAEKADVNCA	EML5	1881	Q05BV3
WISAARVLVDGEEHV	EMC7	61	Q9NPA0
LAVVLLGNEHCDNEW	RXYLT1	196	Q9Y2B1
HWAAFSGCVDIAEIL	EHMT1	911	Q9H9B1
CLVQRILEAWEANDH	PPP6R2	451	O75170
WQEECEEGEGRTIIH	PTPRK	1361	Q15262
CQVGNEAERLGRDHW	SYT9	456	Q86SS6
DHAQGEEDCWVVGRS	VARS2	541	Q5ST30
EVDTRNCSHWAVGVA	RNF135	316	Q8IUD6
DARVGCVTRAWAAEH	TRMT44	561	Q8IYL2
AWTRQLVDGCHRAAE	SNTA1	391	Q13424
AEGQWRAVDVVLDCF	TAPBPL	26	Q9BX59
HDVRLCEEFWGSQER	PRLHR	206	P49683
DLCHVREVGWEEGQK	RERGL	126	Q9H628
LQEVWGHVGADDLCQ	SFTPB	56	P07988
ERCEREWHELEGEFQ	TMEM120B	6	A0PK00
IHCWDVAGAGIIVTE	IMPA1	216	P29218
EHAKALWEDEGVRAC	GNAS	791	Q5JWF2
SAVGHEQVDLDTCWL	LAMA1	2661	P25391
CHAPENVELALREFW	PDIK1L	41	Q8N165
WDHDPEARLTAQCVA	TGFBR2	521	P37173
WIEEECHRVEAQLAL	SNPH	121	O15079
HLAVEAGQEECAKWL	RIPK4	491	P57078
HIVEQCQELEGHWAE	SPTBN5	1596	Q9NRC6
GHWAELERACEARAQ	SPTBN5	1606	Q9NRC6
EQWIAEREVVAGSHE	SPTBN1	1711	Q01082
QEVEDPFRHAWEAGC	SUPT20HL2	331	P0C7V6
KQTDDGRWAHVVCAL	BRPF1	341	P55201
GLESAEQAHEWVKCI	ARAP1	831	Q96P48
GEEVRDALLDPNWHC	CDCA7	306	Q9BWT1
WDHDAEARLSAGCVE	ACVR2B	461	Q13705
DGNVVCAEALWDHVT	SPATA13	146	Q96N96
EEQCLDVVTHWIQEG	PLAUR	141	Q03405
ARIHECQWVVEDAPN	NIBAN1	886	Q9BZQ8
WHAIIVDGHSVEELC	TKT	211	P29401
ICGVVSDAVWDAREQ	RMND5B	101	Q96G75
RALSKEDHGEWECVA	IGSF9B	476	Q9UPX0
EDHGEWECVATNVVT	IGSF9B	481	Q9UPX0
DWDVVDANVVCRQLG	SSC4D	86	Q8WTU2
VCWGHVEEVELINDG	PATJ	241	Q8NI35
ACAEEWQESRTEGEH	TIPRL	86	O75663
ECVRTLDAHEDKVWG	TBL3	596	Q12788
AAASWQVVRGRCVEH	TINF2	16	Q9BSI4
LVDGHDVEALCQAFW	TKTL2	216	Q9H0I9
HRVTWDGAQVCELAQ	VAV1	21	P15498
ARHFLEDVGCWDINA	SCTR	276	P47872
HDGEVWRACIDSNED	TPP2	201	P29144
ECEDTHLGEEVDRNW	NRDC	1026	O43847
GQDCIWGVHVEEDKR	SEZ6	616	Q53EL9
PNGCEAHWEVVERIL	TBC1D13	201	Q9NVG8
LAWVEENQHRVDGAE	PLEC	666	Q15149
HGDVCILNATEWVRE	RWDD2B	146	P57060
KCNGEWVRQVDHVIE	UNC5A	76	Q6ZN44
VAEAVACIQGWEENA	PRSS48	306	Q7RTY5
GACSDIWKVDHVLER	ZNF350	76	Q9GZX5
TCHEAWQGLGEVLQA	TTC7A	811	Q9ULT0
GHLLVEADDVRAWSC	TRIM8	131	Q9BZR9
EADDVRAWSCPQHNA	TRIM8	136	Q9BZR9
CWHGAEAEEAPEQIA	ZNF419	101	Q96HQ0
TEHWVRQEAQGARDC	TRIM62	36	Q9BVG3
HFAEAVNWCDEGLQI	TTC4	166	O95801
QDVIGDLHQCQRTWD	UNC13D	496	Q70J99
QAYLDHVWDEGCAVV	SIVA1	51	O15304
VGEGAREWIRECQHQ	WNT2B	96	Q93097
AGRHCWEVETADAAS	RNF39	281	Q9H2S5
EARESDWDGIIACHQ	WDR36	451	Q8NI36
AGIEDANCWHLDEEQ	ZSWIM4	246	Q9H7M6
CVNRGHVWTDRHVEE	MXRA8	186	Q9BRK3