Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionneurexin family protein binding

NLGN4Y NLGN4X SYTL3

5.94e-0516973GO:0042043
GeneOntologyMolecularFunctionscaffold protein binding

NLGN4Y XIAP PANX1 GRIK2 NLGN4X

9.04e-0593975GO:0097110
GeneOntologyCellularComponentAP-3 adaptor complex

VPS18 AP3M1 AP3M2

2.68e-0513973GO:0030123
GeneOntologyCellularComponentsymmetric, GABA-ergic, inhibitory synapse

NLGN4Y NLGN4X

1.27e-044972GO:0098983
GeneOntologyCellularComponentnuclear envelope

TOR1AIP2 NAPEPLD PARP8 IGF2R NXT1 OSBPL7 NAV3 CPNE1 TNKS2

1.18e-03560979GO:0005635
GeneOntologyCellularComponentAP-type membrane coat adaptor complex

VPS18 AP3M1 AP3M2

1.44e-0348973GO:0030119
GeneOntologyCellularComponentmembrane coat

VPS18 AP3M1 IGF2R AP3M2

1.51e-03106974GO:0030117
GeneOntologyCellularComponentcoated membrane

VPS18 AP3M1 IGF2R AP3M2

1.51e-03106974GO:0048475
GeneOntologyCellularComponentcontractile actin filament bundle

XIRP1 SIPA1L3 CORO1B FSCN1

1.56e-03107974GO:0097517
GeneOntologyCellularComponentstress fiber

XIRP1 SIPA1L3 CORO1B FSCN1

1.56e-03107974GO:0001725
GeneOntologyCellularComponentsymmetric synapse

NLGN4Y NLGN4X

1.61e-0313972GO:0032280
GeneOntologyCellularComponentSwr1 complex

EP400 SRCAP

1.61e-0313972GO:0000812
GeneOntologyCellularComponentneuron projection cytoplasm

GRIK2 AP3M1 OPRM1 AP3M2

1.73e-03110974GO:0120111
GeneOntologyCellularComponenttrans-Golgi network membrane

SLC9A8 HLA-DRB1 IGF2R FUT9

1.85e-03112974GO:0032588
GeneOntologyCellularComponentactomyosin

XIRP1 SIPA1L3 CORO1B FSCN1

2.16e-03117974GO:0042641
GeneOntologyCellularComponentactin filament bundle

XIRP1 SIPA1L3 CORO1B FSCN1

2.23e-03118974GO:0032432
GeneOntologyCellularComponentclathrin coat

AP3M1 IGF2R AP3M2

2.25e-0356973GO:0030118
MousePhenoincreased pancreas weight

CTRB2 OPRM1 CTRB1

1.69e-0511673MP:0009108
DomainNLGN4

NLGN4Y NLGN4X

2.61e-052962IPR030025
DomainWD_REPEATS_1

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2 EIF3B

9.32e-05278968PS00678
DomainWD_REPEATS_2

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2 EIF3B

9.55e-05279968PS50082
DomainWD_REPEATS_REGION

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2 EIF3B

9.55e-05279968PS50294
DomainConA-like_dom

COL27A1 CLSTN2 SVEP1 CELSR2 NBEAL2 SEL1L3 USH2A

1.36e-04219967IPR013320
DomainHSA

EP400 SRCAP

1.56e-044962SM00573
DomainHSA

EP400 SRCAP

1.56e-044962PS51204
DomainHSA_dom

EP400 SRCAP

1.56e-044962IPR014012
DomainHSA

EP400 SRCAP

1.56e-044962PF07529
DomainNlgn

NLGN4Y NLGN4X

2.59e-045962IPR000460
Domain-

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2 EIF3B

3.19e-043339682.130.10.10
DomainWD40/YVTN_repeat-like_dom

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2 EIF3B

3.32e-04335968IPR015943
DomainEGF_1

RELN SVEP1 SNED1 CELSR2 MEGF8 HYAL3 USH2A

3.46e-04255967PS00022
DomainWD40

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2

3.79e-04259967PF00400
DomainClathrin_mu_CS

AP3M1 AP3M2

3.87e-046962IPR018240
DomainCLAT_ADAPTOR_M_1

AP3M1 AP3M2

3.87e-046962PS00990
DomainCLAT_ADAPTOR_M_2

AP3M1 AP3M2

3.87e-046962PS00991
DomainhEGF

SVEP1 SNED1 CELSR2

3.93e-0428963PF12661
DomainWD40

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2

4.66e-04268967SM00320
DomainEGF_LAM_2

CELSR2 MEGF8 USH2A

4.83e-0430963PS50027
DomainEGF_LAM_1

CELSR2 MEGF8 USH2A

4.83e-0430963PS01248
DomainWD40_repeat

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2

5.08e-04272967IPR001680
DomainSNF2_N

EP400 CHD7 SRCAP

5.86e-0432963IPR000330
DomainSNF2_N

EP400 CHD7 SRCAP

5.86e-0432963PF00176
DomainLaminin_EGF

CELSR2 MEGF8 USH2A

7.64e-0435963PF00053
DomainEGF_Lam

CELSR2 MEGF8 USH2A

7.64e-0435963SM00180
DomainWD40_repeat_dom

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2

8.54e-04297967IPR017986
DomainLAM_G_DOMAIN

COL27A1 CELSR2 USH2A

9.74e-0438963PS50025
DomainLaminin_EGF

CELSR2 MEGF8 USH2A

9.74e-0438963IPR002049
DomainClathrin_mu

AP3M1 AP3M2

1.15e-0310962IPR001392
DomainEGF_3

RELN SVEP1 SNED1 CELSR2 MEGF8 HYAL3

1.34e-03235966PS50026
DomainEGF

RELN SVEP1 SNED1 CELSR2 MEGF8 HYAL3

1.34e-03235966SM00181
DomainAdap_comp_sub

AP3M1 AP3M2

1.40e-0311962PF00928
Domain-

CLSTN2 SVEP1 CELSR2 USH2A

1.46e-03959642.60.120.200
DomainOxysterol-bd

OSBPL5 OSBPL7

1.67e-0312962IPR000648
DomainOxysterol-bd_CS

OSBPL5 OSBPL7

1.67e-0312962IPR018494
DomainClathrin_sm-chain_CS

AP3M1 AP3M2

1.67e-0312962IPR000804
DomainOxysterol_BP

OSBPL5 OSBPL7

1.67e-0312962PF01237
DomainOSBP

OSBPL5 OSBPL7

1.67e-0312962PS01013
DomainASX_HYDROXYL

SVEP1 SNED1 CELSR2 MEGF8

1.76e-03100964PS00010
DomainEGF-like_dom

RELN SVEP1 SNED1 CELSR2 MEGF8 HYAL3

1.80e-03249966IPR000742
Domain-

KBTBD6 KBTBD7 MEGF8

1.92e-03489632.120.10.80
DomainMHD

AP3M1 AP3M2

1.97e-0313962PS51072
DomainMHD

AP3M1 AP3M2

1.97e-0313962IPR028565
DomainCarboxylesterase_B_CS

NLGN4Y NLGN4X

1.97e-0313962IPR019819
DomainEGF-type_Asp/Asn_hydroxyl_site

SVEP1 SNED1 CELSR2 MEGF8

2.18e-03106964IPR000152
DomainEGF-like_CS

RELN SVEP1 SNED1 CELSR2 MEGF8 HYAL3

2.28e-03261966IPR013032
DomainDynein_heavy_chain_D4_dom

DNAH3 DNAH9

2.29e-0314962IPR024317
DomainDynein_HC_stalk

DNAH3 DNAH9

2.29e-0314962IPR024743
DomainCARBOXYLESTERASE_B_2

NLGN4Y NLGN4X

2.29e-0314962PS00941
DomainDynein_heavy_dom-2

DNAH3 DNAH9

2.29e-0314962IPR013602
DomainDHC_N2

DNAH3 DNAH9

2.29e-0314962PF08393
DomainMT

DNAH3 DNAH9

2.29e-0314962PF12777
DomainAAA_8

DNAH3 DNAH9

2.29e-0314962PF12780
DomainATPase_dyneun-rel_AAA

DNAH3 DNAH9

2.29e-0314962IPR011704
DomainCOesterase

NLGN4Y NLGN4X

2.29e-0314962PF00135
DomainCarbesteraseB

NLGN4Y NLGN4X

2.29e-0314962IPR002018
DomainAAA_5

DNAH3 DNAH9

2.29e-0314962PF07728
DomainHELICASE_CTER

EP400 CHD7 SRCAP DHX32

2.42e-03109964PS51194
DomainHELICASE_ATP_BIND_1

EP400 CHD7 SRCAP DHX32

2.42e-03109964PS51192
DomainEGF_2

RELN SVEP1 SNED1 CELSR2 MEGF8 HYAL3

2.46e-03265966PS01186
DomainHelicase_ATP-bd

EP400 CHD7 SRCAP DHX32

2.50e-03110964IPR014001
DomainDHC_fam

DNAH3 DNAH9

2.63e-0315962IPR026983
DomainDynein_heavy_dom

DNAH3 DNAH9

2.63e-0315962IPR004273
DomainDynein_heavy

DNAH3 DNAH9

2.63e-0315962PF03028
DomainCCP

CSMD3 SVEP1 SNED1

2.70e-0354963SM00032
DomainKelch-typ_b-propeller

KBTBD6 KBTBD7 MEGF8

2.85e-0355963IPR015915
DomainAP_mu_sigma_su

AP3M1 AP3M2

2.99e-0316962IPR022775
DomainClat_adaptor_s

AP3M1 AP3M2

2.99e-0316962PF01217
DomainSUSHI

CSMD3 SVEP1 SNED1

3.00e-0356963PS50923
DomainSushi_SCR_CCP_dom

CSMD3 SVEP1 SNED1

3.15e-0357963IPR000436
DomainLaminin_G

COL27A1 CELSR2 USH2A

3.31e-0358963IPR001791
DomainPoly(ADP-ribose)pol_cat_dom

PARP8 TNKS2

3.38e-0317962IPR012317
DomainPARP_CATALYTIC

PARP8 TNKS2

3.38e-0317962PS51059
DomainPARP

PARP8 TNKS2

3.38e-0317962PF00644
Domain-

PARP8 TNKS2

3.38e-03179623.90.228.10
DomainGal_Oxase/kelch_b-propeller

KBTBD6 KBTBD7 MEGF8

3.47e-0359963IPR011043
DomainEGF_CA

SVEP1 SNED1 CELSR2 MEGF8

3.62e-03122964SM00179
DomainEGF-like_Ca-bd_dom

SVEP1 SNED1 CELSR2 MEGF8

3.84e-03124964IPR001881
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

CCDC71L EP400 LONRF1 SIPA1L3 PANX1 CORO1B SRCAP IGF2R CELSR2 MEGF8 NBEAL2 OSBPL5 TRAPPC9 HR

3.03e-061105991435748872
Pubmed

Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.

CTRB2 CTRB1

8.02e-06299230076839
Pubmed

The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.

CTRB2 CTRB1

8.02e-06299228951524
Pubmed

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

CTRB2 CTRB1

8.02e-06299228754779
Pubmed

Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.

CTRB2 CTRB1

8.02e-06299233036922
Pubmed

Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.

CTRB2 CTRB1

8.02e-0629922565717
Pubmed

Unusually rapid evolution of Neuroligin-4 in mice.

NLGN4Y NLGN4X

8.02e-06299218434543
Pubmed

Development of an autism severity score for mice using Nlgn4 null mutants as a construct-valid model of heritable monogenic autism.

NLGN4Y NLGN4X

8.02e-06299223183221
Pubmed

Juvenile manifestation of ultrasound communication deficits in the neuroligin-4 null mutant mouse model of autism.

NLGN4Y NLGN4X

8.02e-06299224855039
Pubmed

Sex-specific microglia state in the Neuroligin-4 knock-out mouse model of autism spectrum disorder.

NLGN4Y NLGN4X

8.02e-06299237001827
Pubmed

Increased Network Inhibition in the Dentate Gyrus of Adult Neuroligin-4 Knock-Out Mice.

NLGN4Y NLGN4X

8.02e-06299237080762
Pubmed

Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.

CTRB2 CTRB1

8.02e-0629922917002
Pubmed

Genomic cloning and partial characterization of human chymotrypsinogen gene.

CTRB2 CTRB1

8.02e-0629928186414
Pubmed

Autism Related Neuroligin-4 Knockout Impairs Intracortical Processing but not Sensory Inputs in Mouse Barrel Cortex.

NLGN4Y NLGN4X

8.02e-06299229106499
Pubmed

Perturbed Hippocampal Synaptic Inhibition and γ-Oscillations in a Neuroligin-4 Knockout Mouse Model of Autism.

NLGN4Y NLGN4X

8.02e-06299226456829
Pubmed

Nlgn4 knockout induces network hypo-excitability in juvenile mouse somatosensory cortex in vitro.

NLGN4Y NLGN4X

8.02e-06299224104404
Pubmed

The catalytic subunit of the SWR1 remodeler is a histone chaperone for the H2A.Z-H2B dimer.

EP400 SRCAP

8.02e-06299224507717
Pubmed

A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y.

NLGN4Y NLGN4X

8.02e-06299232243781
Pubmed

Convergent genomic studies identify association of GRIK2 and NPAS2 with chronic fatigue syndrome.

GRIK2 NPAS2

8.02e-06299221912186
Pubmed

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

NLGN4Y NLGN4X

8.02e-06299222989184
Pubmed

RGS14 prevents morphine from internalizing Mu-opioid receptors in periaqueductal gray neurons.

OPRM1 RGS14

8.02e-06299217825524
Pubmed

Evolution of the Autism-Associated Neuroligin-4 Gene Reveals Broad Erosion of Pseudoautosomal Regions in Rodents.

NLGN4Y NLGN4X

2.40e-05399232011705
Pubmed

Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.

CTRB2 CTRB1

2.40e-0539921016231
Pubmed

Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.

CTRB2 CTRB1

2.40e-05399238981616
Pubmed

XIAP 3'-untranslated region as a ceRNA promotes FSCN1 function in inducing the progression of breast cancer by binding endogenous miR-29a-5p.

XIAP FSCN1

2.40e-05399228186968
Pubmed

Analysis of the neuroligin 4Y gene in patients with autism.

NLGN4Y NLGN4X

2.40e-05399218628683
Pubmed

Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.

CTRB2 CTRB1

2.40e-0539921008801
Pubmed

Neuroligin-4 is localized to glycinergic postsynapses and regulates inhibition in the retina.

NLGN4Y NLGN4X

2.40e-05399221282647
Pubmed

Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.

CTRB2 CTRB1

2.40e-05399234643096
Pubmed

The KBTBD6/7-DRD2 axis regulates pituitary adenoma sensitivity to dopamine agonist treatment.

KBTBD6 KBTBD7

2.40e-05399232572597
Pubmed

Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.

CTRB2 CTRB1

2.40e-05399232678161
Pubmed

Hepatitis C virus NS3 protein can activate the Notch-signaling pathway through binding to a transcription factor, SRCAP.

EP400 SRCAP

4.79e-05499221673954
Pubmed

Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism.

NLGN4Y NLGN4X

4.79e-05499212669065
Pubmed

Homodimerization and isoform-specific heterodimerization of neuroligins.

NLGN4Y NLGN4X

4.79e-05499222671294
Pubmed

Ultrasonic vocalizations in mouse models for speech and socio-cognitive disorders: insights into the evolution of vocal communication.

NLGN4Y NLGN4X

4.79e-05499220579107
Pubmed

Analysis of four neuroligin genes as candidates for autism.

NLGN4Y NLGN4X

4.79e-05499216077734
Pubmed

Neuroligins 3 and 4X interact with syntrophin-gamma2, and the interactions are affected by autism-related mutations.

NLGN4Y NLGN4X

4.79e-05499217292328
Pubmed

Association of CD40 gene polymorphism (C-1T) with susceptibility and phenotype of Graves' disease.

HLA-DRB1 CD40

4.79e-05499216279844
Pubmed

Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.

DNAH3 DNAH9

4.79e-05499211175280
Pubmed

RGSZ1 interacts with protein kinase C interacting protein PKCI-1 and modulates mu opioid receptor signaling.

OPRM1 RGS20

7.98e-05599217126529
Pubmed

Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).

CTRB2 CTRB1

7.98e-0559924461036
Pubmed

Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.

CTRB2 CTRB1

7.98e-0559926589791
Pubmed

Association analysis between schizophrenia and the AP-3 complex genes.

AP3M1 AP3M2

7.98e-05599219481122
Pubmed

Polymorphisms of candidate genes in Slovak autistic patients.

RELN NLGN4X

7.98e-05599220436377
Pubmed

LDL-cholesterol concentrations: a genome-wide association study.

TDRD15 CELSR2

7.98e-05599218262040
Pubmed

Neuroligins and neurexins link synaptic function to cognitive disease.

NLGN4Y NLGN4X

7.98e-05599218923512
Pubmed

Synapse formation: if it looks like a duck and quacks like a duck ...

NLGN4Y NLGN4X

7.98e-05599210996085
Pubmed

Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.

CTRB2 CTRB1

7.98e-0559921820020
Pubmed

Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.

NLGN4Y NLGN4X

7.98e-05599237865312
Pubmed

A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.

CLSTN2 NAV3 DNAH9

1.05e-043299323049088
Pubmed

The synaptic protein neuroligin-1 interacts with the amyloid β-peptide. Is there a role in Alzheimer's disease?

NLGN4Y NLGN4X

1.19e-04699221838267
Pubmed

Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

CTRB2 CTRB1

1.19e-04699223814066
Pubmed

Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.

NLGN4Y NLGN4X

1.19e-04699229724786
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

EP400 G2E3 TRIM33 NBEAL2 OSBPL5 EFR3B CPNE1 KDM4A

1.39e-0452999814621295
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TNPO1 EP400 CHD7 CORO1B PWP1 TRIM33

1.61e-0428299623667531
Pubmed

Endometriosis and autoimmune disease: association of susceptibility to moderate/severe endometriosis with CCL21 and HLA-DRB1.

HLA-DRB1 CD40

1.67e-04799220797713
Pubmed

Regulation of Wnt/PCP signaling through p97/VCP-KBTBD7-mediated Vangl ubiquitination and endoplasmic reticulum-associated degradation.

KBTBD6 KBTBD7

1.67e-04799233990333
Pubmed

Characterization of the adaptor-related protein complex, AP-3.

AP3M1 AP3M2

1.67e-0479929151686
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ZHX3 EP400 CSMD3 WDR47 MEGF8 SEL1L3 NAV3

1.69e-0440799712693553
Pubmed

WD40-repeat 47, a microtubule-associated protein, is essential for brain development and autophagy.

ARPC1B WDR47 PWP1

2.05e-044099329078390
Pubmed

Prediction of the coding sequences of unidentified human genes. XIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

SLC9A8 NLGN4Y NAV3 EFR3B

2.12e-0410299410231032
Pubmed

Prediction of the coding sequences of unidentified human genes. XVII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

VPS18 EP400 OSBPL5 CERCAM

2.20e-0410399410819331
Pubmed

Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.

NLGN4Y NLGN4X

2.22e-04899230871858
Pubmed

Association of the AP-3 adaptor complex with clathrin.

AP3M1 AP3M2

2.22e-0489929545220
Pubmed

The mammalian oxysterol-binding protein-related proteins (ORPs) bind 25-hydroxycholesterol in an evolutionarily conserved pocket.

OSBPL5 OSBPL7

2.22e-04899217428193
Pubmed

Isoform diversity in the Arp2/3 complex determines actin filament dynamics.

CORO1B ARPC1B

2.22e-04899226655834
Pubmed

A mouse gene of the paired-related homeobox class expressed in the caudal somite compartment and in the developing vertebral column, kidney and nervous system.

EIF3B FSCN1

2.22e-04899227747430
Pubmed

Spatial proteomics reveal that the protein phosphatase PTP1B interacts with and may modify tyrosine phosphorylation of the rhomboid protease RHBDL4.

TOR1AIP2 CHD7 CORO1B TIPRL IGF2R

2.23e-0419199531177093
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TNPO1 TOR1AIP2 POC1A DEF8 XIAP G2E3 CHD7 COX18 SRCAP AP3M1 IGF2R

2.65e-041084991111544199
Pubmed

Identification of high-molecular-weight proteins with multiple EGF-like motifs by motif-trap screening.

CELSR2 MEGF8

2.85e-0499929693030
Pubmed

Using mouse models of autism spectrum disorders to study the neurotoxicology of gene-environment interactions.

NLGN4Y NLGN4X

2.85e-04999223010509
Pubmed

Linkage and candidate gene studies of autism spectrum disorders in European populations.

RELN GRIK2

2.85e-04999220442744
Pubmed

Microglia ablation alleviates myelin-associated catatonic signs in mice.

NLGN4Y NLGN4X

2.85e-04999229252214
Pubmed

Identification of genes showing altered expression in preimplantation and early postimplantation parthenogenetic embryos.

ARPC1B IGF2R

2.85e-0499928565329
Pubmed

Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.

RELN WDR4 LONRF1 HLA-DRB1 SIPA1L3 DEF8 WDR47 TRIM33 NAV3 CERCAM KDM4A TNKS2

2.94e-041285991235914814
Pubmed

GWAS of longevity in CHARGE consortium confirms APOE and FOXO3 candidacy.

MBOAT1 GRIK2

3.56e-041099225199915
Pubmed

The c-IAP-1 and c-IAP-2 proteins are direct inhibitors of specific caspases.

XIAP CD40

3.56e-04109929384571
Pubmed

HIV-1 Vpu inhibits accumulation of the envelope glycoprotein within clathrin-coated, Gag-containing endosomes.

AP3M1 AP3M2

3.56e-041099218076669
Pubmed

Oligoclonal band status in Scandinavian multiple sclerosis patients is associated with specific genetic risk alleles.

HLA-DRB1 CLSTN2

4.34e-041199223472185
Pubmed

The chromatin remodeling factor CHD7 controls cerebellar development by regulating reelin expression.

RELN CHD7

4.34e-041199228165338
Pubmed

The OSBP-related protein family in humans.

OSBPL5 OSBPL7

4.34e-041199211483621
Pubmed

A genome-wide association study of rheumatoid arthritis without antibodies against citrullinated peptides.

HLA-DRB1 GUCY1B2

4.34e-041199224532677
Pubmed

CUL3-KBTBD6/KBTBD7 ubiquitin ligase cooperates with GABARAP proteins to spatially restrict TIAM1-RAC1 signaling.

KBTBD6 KBTBD7

4.34e-041199225684205
Pubmed

SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.

NLGN4Y NLGN4X

4.34e-041199232973045
Pubmed

Behavioral phenotypes of genetic mouse models of autism.

NLGN4Y NLGN4X

4.34e-041199226403076
Pubmed

A common variant in DRD3 receptor is associated with autism spectrum disorder.

RELN HLA-DRB1 OPRM1 NLGN4X

5.03e-0412899419058789
Pubmed

A family of 12 human genes containing oxysterol-binding domains.

OSBPL5 OSBPL7

5.20e-041299211735225
Pubmed

An oxysterol-binding protein family identified in the mouse.

OSBPL5 OSBPL7

5.20e-041299212215260
Pubmed

Genome-wide association study identifies new multiple sclerosis susceptibility loci on chromosomes 12 and 20.

HLA-DRB1 CD40

6.13e-041399219525955
Pubmed

N-CoR mediates DNA methylation-dependent repression through a methyl CpG binding protein Kaiso.

TRIM33 KDM4A

6.13e-041399214527417
Pubmed

Advancing the understanding of autism disease mechanisms through genetics.

NLGN4Y NLGN4X

6.13e-041399227050589
Pubmed

Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cells.

CTRB2 CTRB1

6.13e-041399211468771
Pubmed

An interaction network of the mammalian COP9 signalosome identifies Dda1 as a core subunit of multiple Cul4-based E3 ligases.

TOR1AIP2 KBTBD6 PWP1

6.48e-045999319295130
Pubmed

Cumulative association of 22 genetic variants with seropositive rheumatoid arthritis risk.

HLA-DRB1 CD40

8.22e-041599220233754
Pubmed

Evolutionarily conserved intercalated disc protein Tmem65 regulates cardiac conduction and connexin 43 function.

TNPO1 XIRP1

8.22e-041599226403541
Pubmed

Connexin Expression Is Altered in Liver Development of Yotari (dab1 -/-) Mice.

RELN PANX1

8.22e-041599234639052
Pubmed

Reduced social interaction and ultrasonic communication in a mouse model of monogenic heritable autism.

NLGN4Y NLGN4X

8.22e-041599218227507
Pubmed

Common variants at CD40 and other loci confer risk of rheumatoid arthritis.

HLA-DRB1 CD40

8.22e-041599218794853
Pubmed

Genetic variants in the prediction of rheumatoid arthritis.

HLA-DRB1 CD40

9.38e-041699220439292
Pubmed

Specific glial populations regulate hippocampal morphogenesis.

RELN GRIK2

9.38e-041699219020026
Cytoband13q14.11

KBTBD6 KBTBD7 WBP4

8.40e-053999313q14.11
CytobandEnsembl 112 genes in cytogenetic band chr7q22

CCDC71L RELN NAPEPLD ZSCAN25 ARPC1B

1.17e-04219995chr7q22
GeneFamilyWD repeat domain containing

POC1A WDR4 CORO1B ARPC1B WDR47 PWP1 NBEAL2

6.82e-05262707362
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL5 OSBPL7

9.51e-0412702670
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

CSMD3 SVEP1 SNED1

1.40e-03577031179
GeneFamilyDyneins, axonemal

DNAH3 DNAH9

1.94e-0317702536
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP8 TNKS2

1.94e-0317702684
GeneFamilyRegulators of G-protein signaling

RGS14 RGS20

2.96e-0321702720
CoexpressionGSE4142_NAIVE_VS_MEMORY_BCELL_UP

SLC39A2 WDR47 SNED1 TRIM33 CD40 AP3M2 CPNE1

9.44e-06199977M6388
ToppCellCOVID-19-kidney-Technical/muscle_(Mes)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 RELN CSMD3 NAV3 USH2A DNAH9

1.51e-061599965335cbcdeaf2bbd0268bbfe0e45c8c0d288e640d
ToppCellCOVID-19-kidney-Technical/muscle_(Imm)|kidney / Disease (COVID-19 only), tissue and cell type

DNAH3 RELN CSMD3 RGS20 USH2A DNAH9

1.75e-0616399619c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCellAdult-Mesenchymal-chondrocyte-D175|Adult / Lineage, Cell type, age group and donor

MIX23 KBTBD6 COL27A1 CLSTN2 PWP1 NAV3

2.08e-0616899614071b961c9bdb54a8259b12a88237b802cbde36
ToppCellCOVID-19_Moderate-B_memory|World / disease group, cell group and cell class

UTS2B LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

3.11e-061809962f37187b866edb56410c2334b72713f2248dc335
ToppCellCOVID-19_Moderate-B_memory|COVID-19_Moderate / disease group, cell group and cell class

UTS2B LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

3.31e-06182996bbdbef62389ac062118cc0c7979686393399f2c8
ToppCellICU-SEP-Lymphocyte-B-B_memory|ICU-SEP / Disease, Lineage and Cell Type

UTS2B LYPLAL1 NLGN4Y HLA-DRB1 CD40 SEL1L3

3.99e-06188996b6d81be72bbd72a68722ab51d1a72c436ef9bc17
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LYPLAL1 HLA-DRB1 DEF8 ARPC1B CD40 SEL1L3

4.92e-06195996cccc9c70bb8f6df8c6ab94534c17475af1d3e224
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 PWP1 SNED1 CD40 SEL1L3 EIF3B

5.07e-061969960175b097ad1338a07afebe3b5c7fd0bb0bb950f7
ToppCellMS-IIF-Lymphocyte-B-B_memory|IIF / Disease, condition lineage and cell class

LYPLAL1 HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

5.37e-06198996ae6f1d3ca7d7aa6f6f45b6b51aa8a967cadde017
ToppCellSepsis-ICU-SEP-Lymphocyte-B-B_memory|ICU-SEP / Disease, condition lineage and cell class

UTS2B LYPLAL1 NLGN4Y HLA-DRB1 CD40 SEL1L3

5.37e-061989964ba2eb32889bbf043f4bbb822e08eb45a2b576ef
ToppCellmild-B_memory|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

UTS2B LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

5.53e-06199996025bb65629d9e20c374e8f1ba08c36d1bb569190
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-B-B_memory|COVID-19_Mild / Disease, condition lineage and cell class

LYPLAL1 HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

5.53e-0619999654e392b4ebe601d4838739ff7de3ac6b2203c948
ToppCellSepsis-Int-URO-Lymphocyte-B-B_memory|Int-URO / Disease, condition lineage and cell class

UTS2B LYPLAL1 HLA-DRB1 RGS20 CD40 SEL1L3

5.53e-061999967cddf15aeb65df17f737bb3144d6579ec5a1ea27
ToppCellCOVID-19-kidney-Mito-rich_Int|kidney / Disease (COVID-19 only), tissue and cell type

RELN CSMD3 SVEP1 CTRB1 DNAH9

1.03e-0512999557b705106aec7bbfc587de1ccd4f2335fc44dd6f
ToppCellLPS_only-Epithelial_airway-Ciliated_cells-Ciliated|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 LRRC9 FAM227A USH2A DNAH9

2.43e-051549959ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCellLPS_only-Epithelial_airway-Ciliated_cells|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

DNAH3 LRRC9 FAM227A USH2A DNAH9

2.43e-0515499558072ce422d09f2de602580325eaac6c4ec6c136
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

PARP8 SYTL3 AP3M2 FAM227A DNAH9

2.58e-0515699510d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellmetastatic_Brain-Fibroblasts-Myofibroblasts|Fibroblasts / Location, Cell class and cell subclass

DNAH3 CTRB2 GRIK2 NLGN4X FSCN1

2.75e-05158995ab05f6d7968ccd6d3826cd71b763dbedc83822c3
ToppCellfacs-Marrow-B-cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SLC39A2 SEL1L3 FSCN1 HR

3.38e-05165995361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell3'_v3-blood-Lymphocytic_B-ABC_aged-B_memory|blood / Manually curated celltypes from each tissue

UTS2B HLA-DRB1 INSL6 CD40 SEL1L3

3.68e-051689952ce1a30feb2704a9516d1dab161a26cb0555abb5
ToppCell5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DNAH3 LRRC9 SNED1 FAM227A DNAH9

3.79e-05169995fba841664939c771881ba97f14ef1df6635c04ff
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NAPEPLD CLSTN2 SEL1L3 FUT9 CERCAM

3.90e-051709955d5f208682be21ed58320f5fc083a7898f8712da
ToppCellBac-SEP-Lymphocyte-B-B_memory|Bac-SEP / Disease, Lineage and Cell Type

UTS2B LYPLAL1 HLA-DRB1 CD40 SEL1L3

3.90e-0517099586db153984437ef1447eae8ef30a40be0925ffd5
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS9 G2E3 AP3M1 HYAL3 TUBAL3

4.24e-051739958bffd512a4e561e23cc04478e2ca6fd5d3771fe4
ToppCellfacs-Marrow-KLS-3m-Lymphocytic-immature_B_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMPRSS9 G2E3 AP3M1 HYAL3 TUBAL3

4.24e-051739953e3c61468e703330788a10d850ef41a85680f86d
ToppCellwk_20-22-Epithelial-PNS|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RELN GRIK2 CLSTN2 NLGN4X HR

4.24e-0517399517b1a6b0318925d5d920f2c0a791745b9587ebef
ToppCellPCW_13-14-Neuronal-Neuronal_SCP-neuro_SCP_(0)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN GRIK2 ARPC1B NLGN4X HR

4.35e-051749950d8e737860120dcd3a6b57992c612595904d585e
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN4Y GRIK2 SVEP1 NLGN4X HR

4.35e-051749959c916af5eebd932f67dc9117e1d26ff194a2ff2c
ToppCellkidney_cells-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NLGN4Y GRIK2 SVEP1 NLGN4X HR

4.35e-05174995bc71521f44a5fe013af42b06b5d1bd2446ecf3b5
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

LYPLAL1 HLA-DRB1 DEF8 CD40 SEL1L3

4.35e-05174995fde40c5d51f5380088360dc5a583eb04e518deb6
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL27A1 INSL6 CD40 KDM4A FSCN1

4.47e-051759951b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellIIF-Lymphocyte-B-B_intermediate|IIF / Disease, Lineage and Cell Type

UTS2B HLA-DRB1 SIPA1L3 CD40 SEL1L3

4.47e-05175995327f8ee3669c3fc5ba50abc3b4f3e068637fd8d8
ToppCellfacs-Marrow-B-cells-24m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIK2 CSMD3 CTRB1 USH2A DNAH9

4.47e-05175995887e75fc90e59a6394d62f3c048a9cfdf6707725
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

COL27A1 CHD7 INSL6 CERCAM FSCN1

4.60e-0517699524b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellfacs-Marrow-B-cells-18m-Hematologic-Unknown_Progenitor|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SLC39A2 SEL1L3 FSCN1 HR

4.60e-051769955f9ae5eb45603ed0422a3a993ecdbe2ce05d6e45
ToppCellwk_20-22-Epithelial-PNS-Late_Schwann|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

RELN GRIK2 CLSTN2 NLGN4X HR

4.60e-0517699581924471d8a8c5bd8eedf294c007e25b6cd3e417
ToppCellBAL-Mild-cDC_3|Mild / Compartment, Disease Groups and Clusters

ZSCAN25 KBTBD7 RGS14 OSBPL7 CERCAM

4.60e-05176995f9b0c3ced391e7ebe6b242d3f12ba14741f88d22
ToppCellwk_15-18-Epithelial-PNS-Schwann_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

TMPRSS9 GRIK2 CHD7 NLGN4X CELSR2

4.72e-051779955357359e6c2161a37f39a6b3b78449f5cbc327d1
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

COL27A1 CHD7 INSL6 CERCAM FSCN1

4.72e-05177995f360f7099570d248531897b96e0de282e58f59e9
ToppCellfacs-Marrow-B-cells-18m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN SLC39A2 SEL1L3 FSCN1 HR

4.72e-0517799535d42b07d9c31528bf59199e361bb8a3bfbe3b75
ToppCellPCW_13-14-Neuronal-Neuronal_SCP|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

RELN GRIK2 ARPC1B NLGN4X HR

4.72e-05177995621dd82f1393c961d4dd7a615aa52c9df9e36336
ToppCellnormal_Lymph_Node-B_lymphocytes-GC_B_cells_in_the_LZ|normal_Lymph_Node / Location, Cell class and cell subclass

LYPLAL1 HLA-DRB1 DEF8 CD40 SEL1L3

4.85e-05178995d75057e7463558a0d3cebde3c30befbf4704dd9a
ToppCellControl-Stromal_mesenchymal-Matrix_Fibroblast-MatrixFB|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMPRSS9 COL27A1 SVEP1 SNED1 NAV3

5.12e-0518099508ae0f5d95c45feba68ad99788f7af7ff4c979af
ToppCell10x5'-Liver-Lymphocytic_B-Memory_B_cells|Liver / Manually curated celltypes from each tissue

UTS2B HLA-DRB1 NLGN4X CD40 SEL1L3

5.25e-05181995a9f4df288c34e3b2b6ed861ac6cda970c3ee08b1
ToppCellnormal-na-Lymphocytic_B-B_mem-male|normal / PBMC cell types (v2) per disease, treatment status, and sex

NLGN4Y HLA-DRB1 CHD7 CD40 SEL1L3

5.39e-05182995ee36ea6cb9a5a08aeb83f2b7a249255f0b1a9870
ToppCellBALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 SIPA1L3 CLSTN2 CD40 SEL1L3

5.39e-05182995ccd729388d997cc45071175cb0c3db6d0790eaf8
ToppCell3'-GW_trimst-1-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RELN CLSTN2 ARPC1B CELSR2 HR

5.53e-05183995547b1fb9f9940cfc8d6e351d96acc0da44def57e
ToppCellControl-Lymphocyte-B-B_memory|Control / Disease, Lineage and Cell Type

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

5.53e-05183995491fa04a1d2caeeec6c6403c9a38b4a1257fc2bc
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CSMD3 NAV3 USH2A DNAH9

5.68e-051849952cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CSMD3 NAV3 USH2A DNAH9

5.68e-05184995ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellHealthy/Control-B_memory|World / Disease group and Cell class

UTS2B LYPLAL1 CHD7 CD40 SEL1L3

5.68e-051849959e1879d86b535ede9b47deb0752e291f987a5d5e
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RELN CSMD3 NAV3 USH2A DNAH9

5.68e-051849952b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellIIF-Lymphocyte-B-B_memory|IIF / Disease, Lineage and Cell Type

LYPLAL1 HLA-DRB1 PWP1 CD40 SEL1L3

5.82e-05185995c0eeab45c4ddefe107690a4ba8868fed2962c730
ToppCellSmart-seq2-lymph_node_(Smart-seq2)-lymphocytic-B_lymphocytic-memory_B_cell|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

5.82e-0518599538e07b3f846f8a929c22424a526b69bf66e0b220
ToppCellfacs-Mammary_Gland-Mammary_Gland-21m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBOAT1 RGS14 INSL6 SYTL3 DNAH9

5.98e-0518699502fbb02c495e7d64c4ab50e42e5197782f2c0816
ToppCell5'-GW_trimst-1.5-LargeIntestine-Neuronal-Glial_immature-ENCC/glia_Progenitor|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMPRSS9 CHD7 ARPC1B CELSR2 FSCN1

5.98e-0518699576535681667c8afb884fa72b6edfee9e1e46335b
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

B3GALT5 GRIK2 SEL1L3 FUT9 NPAS2

6.13e-05187995ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

UTS2B LYPLAL1 HLA-DRB1 CD40 SEL1L3

6.13e-05187995ea56cfca919a09db852b7ee5e42323f822962465
ToppCellControl-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

HLA-DRB1 SIPA1L3 SNED1 CD40 SEL1L3

6.13e-051879954e64be635f445276e71f2937f33f041c3a4204ab
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

UTS2B LYPLAL1 HLA-DRB1 CD40 SEL1L3

6.13e-0518799543f81863063509337bd56a67010c62fb51109bd5
ToppCellIPF-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

HLA-DRB1 SIPA1L3 SNED1 CD40 SEL1L3

6.13e-05187995af1327559f7e01bec070881cae52834917c3da65
ToppCellMultiple_Sclerosis-Lymphocyte-B-B_memory|Multiple_Sclerosis / Disease, Lineage and Cell Type

UTS2B LYPLAL1 HLA-DRB1 CD40 SEL1L3

6.29e-051889958da631b2c75441b7309f03e7d4c14f15f2367be6
ToppCellControl-Lymphoid_B-B_memory|Control / Disease group, lineage and cell class

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.29e-05188995ba4245de3bee29118abab57c4fce60b2007a189c
ToppCellPCW_05-06-Endothelial-Endothelial_immature-endo_immature4_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

SLC22A24 CD40 SEL1L3 NAV3 NPAS2

6.29e-05188995b9c5d573fc5ab0f7f38c55d006f9576634b05462
ToppCellPBMC-Convalescent-Lymphocyte-B-B_cell-B_memory|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

UTS2B LYPLAL1 HLA-DRB1 CD40 SEL1L3

6.29e-05188995b6ae707b033a17c75ca81f9194631ead1b63d170
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-B_memory-3|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.29e-05188995cd833a125a5279ac32a9a9cb9ecd05ae24bea3a9
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.29e-051889959256c5f45c97df209bb9c322c3b557d4f726a333
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-B_memory-3|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.44e-05189995ac0203f17b481d608587113ea2de0f383b29ed27
ToppCellremission-B_memory|World / disease stage, cell group and cell class

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.61e-05190995c3f55f752e47b5a71e111367cdbed4a39ab5cb21
ToppCellwk_08-11-Epithelial-PNS-Schwann_precursor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

TMPRSS9 GRIK2 CHD7 NLGN4X FSCN1

6.61e-051909954a777d8aa19cadd3b61b023772df142421a89113
ToppCellCOPD-Lymphoid-B|Lymphoid / Disease state, Lineage and Cell class

HLA-DRB1 SIPA1L3 SNED1 CD40 SEL1L3

6.61e-051909951e85ee686ff6dd27c69415d524d54fa825b1daad
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.77e-0519199503f6da73e7b706252d2096507222229c4101a27b
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_memory-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.77e-05191995578b58782e816ecaeabfbc616ceb1dcd53ee428b
ToppCellSmart-seq2-bone_marrow_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|bone_marrow_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

KBTBD6 CSMD3 KBTBD7 IGF2R NBEAL2

6.77e-05191995d4f77c73311d1149466bbfe4adbd6a301946ec90
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.77e-0519199522134a2c1a92208bc1629a620ce73a56502613c2
ToppCellsevere_COVID-19-B_memory|World / disease group, cell group and cell class (v2)

UTS2B HLA-DRB1 CHD7 CD40 SEL1L3

6.77e-051919953b57e353b74ebc866d0e11deeba31fa764c42325
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-B_intermediate-0|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DRB1 SIPA1L3 CHD7 CD40 SEL1L3

6.77e-051919955a9a592875fbd0b1429b48db29a760fdc9c2c856
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 SIPA1L3 CHD7 CD40 SEL1L3

6.94e-05192995446c61c0d6ba89c619efe87ee495951299953981
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.94e-0519299575ce635d669ff77d1fd54e10467f21d5e5d67b08
ToppCellsystemic_lupus_erythematosus-managed-Lymphocytic_B-B_mem-male|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

UTS2B LYPLAL1 HLA-DRB1 CD40 SEL1L3

6.94e-05192995185dd150d3345cd29625052a46f3ed89f2a9a8f6
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.94e-05192995debd471f61cf3606b8e9c246add0be5df601af7f
ToppCellcontrol-B_memory|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.94e-05192995d6ef271b6c4f9b49323650f3f773abd61c1b13c3
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_B-B_mem-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.94e-0519299580a71ab3434076803466ccac0df73468889c7dd3
ToppCellCOVID-19_Mild-Lymphoid_B-B_memory|COVID-19_Mild / Disease group, lineage and cell class

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.94e-05192995d27db7669de95bddbea8ccb83e6f10ae7240b1ab
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_memory|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

6.94e-05192995314f74dd3c6d94839eed05b9a1a398217ef78029
ToppCellIPF-Lymphoid-T|World / Disease state, Lineage and Cell class

PARP8 CORO1B OPRM1 SYTL3 AP3M2

6.94e-05192995b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCellHealthy_donor-B_intermediate|World / disease group, cell group and cell class (v2)

TDRD15 UTS2B HLA-DRB1 CD40 SEL1L3

6.94e-05192995f77007b284e11f8654ad599eef929df7c6c4ebf0
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

HLA-DRB1 SIPA1L3 CHD7 CD40 SEL1L3

7.11e-051939957cc10e8b51091869d46e462f3214999e7b5348b1
ToppCellmild_COVID-19-B_memory|World / disease group, cell group and cell class (v2)

HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

7.11e-0519399569b70c838328fdc7dbb6b5449fe2811a5389a839
ToppCellmild_COVID-19-B_memory|mild_COVID-19 / disease group, cell group and cell class (v2)

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

7.11e-051939957e6fe70928a50b0a8f12220e572c07c5670d092e
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

TNPO1 XIAP G2E3 TRIM33 IGF2R

7.11e-05193995abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

7.11e-05193995ac227ddabfb3f021b1b39dba73f898517cd5a58e
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c03-CD27-AIM2|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

LYPLAL1 HLA-DRB1 PWP1 CD40 SEL1L3

7.11e-051939959f798a1bbd9f076c3122d02ed28418c18bb7a369
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

7.11e-05193995f4135615ee0118eec9e221becdd67888e0c2a112
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_B-B_cell-B_c02-MS4A1-CD27|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 CHD7 PWP1 CD40 SEL1L3

7.29e-051949955cd72330c9d9bb21b6c9d5d35085eade101486d1
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

HLA-DRB1 SIPA1L3 CHD7 CD40 SEL1L3

7.29e-051949952b61023a602d336ed0de174e9141046173db34e6
ToppCellCOVID-19_Mild-Lymphoid_B-B_intermediate|COVID-19_Mild / Disease group, lineage and cell class

HLA-DRB1 SIPA1L3 CHD7 CD40 SEL1L3

7.29e-05194995bf6f72a489c62cbf1a679552d8c5eaaaa0b99d33
ToppCellPBMC-Mild-Lymphocyte-B-B_cell-B_intermediate-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

HLA-DRB1 SIPA1L3 CHD7 CD40 SEL1L3

7.29e-05194995f2486b19ac52a48d19f80b38a5536bee3dad745b
ToppCellsystemic_lupus_erythematosus-flare-Lymphocytic_B-B_mem|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

LYPLAL1 HLA-DRB1 CHD7 CD40 SEL1L3

7.29e-0519499540c7f9bd69a8e843b81972e25a67f591021415dd
ToppCellsaliva-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

HLA-DRB1 PWP1 CD40 SEL1L3 EIF3B

7.47e-05195995a4d36654b968acb1aea252ac203683939461f1d1
DrugUroguanylin

SLC39A2 CTRB2 GUCY1B2 CTRB1

1.64e-0536974CID005488765
Drugc189

CTRB2 CTRB1

1.80e-052972CID000248048
DrugBOCPheONP

CTRB2 CTRB1

1.80e-052972CID000111308
Drugdansyl-D-arginine methyl ester

CTRB2 CTRB1

1.80e-052972CID000191369
DrugMPM-06

CTRB2 CTRB1

1.80e-052972CID000161546
Drugmethyl 6-phenylhexanoate

CTRB2 CTRB1

1.80e-052972CID011820300
DrugNSC-374899

CTRB2 CTRB1

1.80e-052972CID000435726
Drug5-aminotetrazole

CTRB2 CTRB1

1.80e-052972CID000020467
Drug2-bromoisobutyric acid

CTRB2 CTRB1

1.80e-052972CID000074924
Drugp-toluamidine

CTRB2 CTRB1

1.80e-052972CID000122753
Drugmethylbenzenebutanoate

CTRB2 CTRB1

1.80e-052972CID000281254
DrugN-acetyl-alpha-azaphenylalanine phenyl ester

CTRB2 CTRB1

1.80e-052972CID000191275
DrugAsp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu

CTRB2 CTRB1

1.80e-052972CID004418081
Drugisobutyl sulfide

CTRB2 CTRB1

1.80e-052972CID000011607
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

WDR4 SIPA1L3 GRIK2 SRCAP RGS14 MEGF8 CD40

2.10e-051969774574_DN
DrugzLYCK

NAPEPLD CTRB2 CTRB1

4.03e-0516973CID000171556
Drug3-amino-2-pyridone

CTRB2 CTRB1

5.37e-053972CID000322353
DrugASA-BMPA

CTRB2 CTRB1

5.37e-053972CID003035649
Drugp-nitrophenyl benzoate

CTRB2 CTRB1

5.37e-053972CID000070396
DrugN-acetylbenzotriazole

CTRB2 CTRB1

5.37e-053972CID000087784
DrugZ-Phe-OMe

CTRB2 CTRB1

5.37e-053972CID003082435
Drugphotophor

CTRB2 CTRB1

5.37e-053972CID000014780
Drug3-methylcoumarin

CTRB2 CTRB1

5.37e-053972CID000017130
Drugdibutyl iodomethaneboronate

CTRB2 CTRB1

5.37e-053972CID000098591
Drugzinc;dipicolinate

CTRB2 CTRB1

5.37e-053972CID004309911
Drug2-propyl methylphosphonochloridate

CTRB2 CTRB1

5.37e-053972CID000102124
Drug2-oxobut-3-ynoate

CTRB2 CTRB1

5.37e-053972CID000171547
DrugAFMeq

CTRB2 CTRB1

5.37e-053972CID000194069
DrugBz-Cti-otbu

CTRB2 CTRB1

5.37e-053972CID006452691
Drugn-(2-oxoethyl)benzamide

CTRB2 CTRB1

5.37e-053972CID000188995
DrugAC1L49DM

CTRB2 CTRB1

5.37e-053972CID000152933
DrugFK-316

CTRB2 CTRB1

5.37e-053972CID000133688
DrugAC1L19T8

CTRB2 CTRB1

5.37e-053972CID000000694
DrugMarinostatin D

CTRB2 CTRB1

5.37e-053972CID000132206
Drugc140

CTRB2 CTRB1

5.37e-053972CID002783250
Drug1FD7

CTRB2 CTRB1

5.37e-053972CID000445579
DrugBenzamidomethaneboronic acid

CTRB2 CTRB1

5.37e-053972CID000127677
Drugphenyl hippurate

CTRB2 CTRB1

5.37e-053972CID000076323
DrugFK-386

CTRB2 CTRB1

5.37e-053972CID000135044
DrugFK-375

CTRB2 CTRB1

5.37e-053972CID000135042
Drugcarbostyril-124

CTRB2 CTRB1

5.37e-053972CID000088277
DrugN-trifluoroacetyl-4-fluorophenylalanine

CTRB2 CTRB1

5.37e-053972CID000328214
DrugGlt-leu-phe-nh-meq

CTRB2 CTRB1

5.37e-053972CID000194914
DrugAC1L4Z4F

CTRB2 CTRB1

5.37e-053972CID000194913
DrugGlt-Phe-NH-FMeq

CTRB2 CTRB1

5.37e-053972CID000194912
DrugC18 4

CTRB2 CTRB1

5.37e-053972CID000077248
Drugdiacetyl trimer

CTRB2 CTRB1

5.37e-053972CID000193527
DrugFK-448

CTRB2 CTRB1

5.37e-053972CID006917869
DrugAc-Phe-OMe

CTRB2 CTRB1

5.37e-053972CID000097805
Drugtaraxastane

CTRB2 CTRB1

5.37e-053972CID006429404
Drugthiobenzyl N-heptafluorobutyrylanthranilate

CTRB2 CTRB1

5.37e-053972CID000133906
DrugPhe-phe-ome

CTRB2 CTRB1

5.37e-053972CID000151728
Drugphenylethaneboronic acid

CTRB2 CTRB1

5.37e-053972CID000065389
Drugacetyltryptophanamide

CTRB2 CLSTN2 CTRB1

9.43e-0521973CID000002003
DrugBenzoyl-dl-leucine

CTRB2 CTRB1

1.07e-044972CID000294887
DrugAcafcek

CTRB2 CTRB1

1.07e-044972CID000197677
Drugp-fluorobenzenesulfonyl chloride

CTRB2 CTRB1

1.07e-044972CID000009588
DrugBSSDA

CTRB2 CTRB1

1.07e-044972CID003081106
DrugB-1,3-od

CTRB2 CTRB1

1.07e-044972CID011971053
DrugAC1L2HV6

CTRB2 CTRB1

1.07e-044972CID000047328
Drugdehydromerodesmosine

CTRB2 CTRB1

1.07e-044972CID006443540
DrugAC1L4X1Z

CTRB2 CTRB1

1.07e-044972CID000193815
Drugalpha-amyrin palmitate

CTRB2 CTRB1

1.07e-044972CID000185477
Drugpoly-THIQ

CTRB2 CTRB1

1.07e-044972CID006453487
DrugNSC-676827

CTRB2 CTRB1

1.07e-044972CID000385555
DrugN-(4-carboxycyclohexylmethyl)-maleimide

CTRB2 CTRB1

1.07e-044972CID011548799
DrugG2505_sigma

CTRB2 CTRB1

1.07e-044972CID000111098
Drug6-amino-1,2-benzopyrone

CTRB2 CTRB1

1.07e-044972CID000046152
Drugnitrophenylethanol

CTRB2 CTRB1

1.07e-044972CID000097851
Drugethanolamine-O-sulfate

CTRB2 PANX1 FSCN1 CTRB1

1.34e-0461974CID000070223
Drug7-chloro-4-nitrobenzofuran

CTRB2 CTRB1

1.78e-045972CID000130782
DrugAc-Trp-OEt

CTRB2 CTRB1

1.78e-045972CID000304749
DrugZ-Phe-Leu

CTRB2 CTRB1

1.78e-045972CID000333351
Drug5'-FSBAzA

CTRB2 CTRB1

1.78e-045972CID000130430
DrugAC1L3F57

CTRB2 CTRB1

1.78e-045972CID000139565
Drugapne

CTRB2 CTRB1

1.78e-045972CID000098192
Drug3,5-dimethylpyrazole-1-carboxamidine

CTRB2 CTRB1

1.78e-045972CID000097525
DrugMaap-borov

CTRB2 CTRB1

1.78e-045972CID005486914
Drug2-amino-4,6-dichlorotriazine

CTRB2 CTRB1

1.78e-045972CID000013615
DrugAC1O52A0

CTRB2 CTRB1

1.78e-045972CID006475891
Drugallysine aldol

CTRB2 CTRB1

1.78e-045972CID000191270
DrugFenspiride hydrochloride [5053-08-7]; Up 200; 13.4uM; HL60; HG-U133A

SLC9A8 SIPA1L3 DEF8 SRCAP NBEAL2 TNKS2

1.84e-041949761422_UP
DrugAtovaquone [95233-18-4]; Up 200; 11uM; MCF7; HT_HG-U133A

EFCAB11 PARP8 GRIK2 RGS14 CD40 HR

1.84e-041949764786_UP
DrugAC1L9M3D

CTRB2 OTC CTRB1

2.04e-0427973CID000448563
DrugCP-944629 [668990-94-1]; Up 200; 10uM; PC3; HT_HG-U133A

SLC9A8 WDR4 SIPA1L3 CHD7 SRCAP NBEAL2

2.05e-041989767549_UP
DrugCephalothin sodium salt [58-71-9]; Up 200; 9.6uM; MCF7; HT_HG-U133A

RELN SRCAP RGS14 MEGF8 EFR3B HR

2.05e-041989766079_UP
DrugMebhydroline 1,5-naphtalenedisulfonate [6153-33-9]; Down 200; 4.8uM; MCF7; HT_HG-U133A

WDR4 EP400 WBP4 CD40 FSCN1 ALDH6A1

2.11e-041999764795_DN
DrugMethapyrilene hydrochloride [135-23-9]; Up 200; 13.4uM; MCF7; HT_HG-U133A

ZHX3 SVEP1 SNED1 CD40 EFR3B NPAS2

2.11e-041999763205_UP
Drugconta-1(35),3,5,7(37),8,10,12,15,32(36),33-decaene-30-carboxylic acid

CTRB2 OPRM1 TAS1R2 CTRB1

2.55e-0472974CID000489933
Drugoctyl isocyanate

CTRB2 CTRB1

2.66e-046972CID000076616
DrugAsp-Asp-Asp-Asp

CTRB2 CTRB1

2.66e-046972CID004432006
DrugN-benzoyl-L-tyrosine thiobenzyl ester

CTRB2 CTRB1

2.66e-046972CID000191444
DrugLeupeptin acid

CTRB2 CTRB1

2.66e-046972CID000189069
DrugSri 8835

CTRB2 CTRB1

2.66e-046972CID000479975
DrugN,N-dimethylglycylbenzocaine

CTRB2 CTRB1

2.66e-046972CID000188251
DrugN-benzoyltyrosine butylamide

CTRB2 CTRB1

2.66e-046972CID000125261
DrugD-gluconyl-glycine azide

CTRB2 CTRB1

2.66e-046972CID000194550
Drug2-azidoatrazine

CTRB2 CTRB1

2.66e-046972CID003032432
DrugL-659,286

CTRB2 CTRB1

2.66e-046972CID000128954
Drugbz-Ala-OMe

CTRB2 CTRB1

2.66e-046972CID000023671
Diseasetriglycerides in IDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2 TNKS2

1.38e-0658975EFO_0022149
Diseasevery low density lipoprotein cholesterol measurement, lipid measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2 CPNE1 TNKS2

8.47e-06220977EFO_0004529, EFO_0008317
Diseaselevel of chymotrypsinogen B2 in blood serum

CTRB2 CTRB1

1.07e-052972OBA_2041192
Diseasevery low density lipoprotein cholesterol measurement, phospholipid measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2 CPNE1 TNKS2

1.10e-05229977EFO_0004639, EFO_0008317
Diseasetriglycerides in large LDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

1.23e-0543974EFO_0022319
Diseasetriglyceride measurement, low density lipoprotein cholesterol measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2 TNKS2

1.87e-05166976EFO_0004530, EFO_0004611
Diseasephospholipids in medium LDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

2.08e-0549974EFO_0022183
Diseasetotal lipids in LDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

2.63e-0552974EFO_0022308
Diseasetotal lipids in medium VLDL

TDRD15 HLA-DRB1 IGF2R CELSR2

3.06e-0554974EFO_0022153
Diseaseperipheral arterial disease

HLA-DRB1 CSMD3 CELSR2 SYTL3

3.06e-0554974EFO_0004265
Diseasechymotrypsinogen B measurement

CTRB2 CTRB1

3.20e-053972EFO_0801477
Diseasetriglyceride measurement, intermediate density lipoprotein measurement

HLA-DRB1 IGF2R CELSR2 CPNE1 TNKS2

3.37e-05111975EFO_0004530, EFO_0008595
Diseasetriglycerides in LDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

3.53e-0556974EFO_0022320
Diseasephospholipids in VLDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

4.35e-0559974EFO_0022301
Diseasetotal lipids in VLDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

4.65e-0560974EFO_0022314
Diseasefree cholesterol in VLDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

4.96e-0561974EFO_0022276
Diseasetriglycerides in medium LDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

5.29e-0562974EFO_0022322
Diseasecholesterol in large VLDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

6.37e-0565974EFO_0021902
Diseasecholesterol in very large VLDL measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

6.37e-0565974EFO_0022230
Diseasetotal lipids in small VLDL

TDRD15 HLA-DRB1 IGF2R CELSR2

7.18e-0567974EFO_0022148
Diseaselongevity, healthspan, parental longevity

HLA-DRB1 DEF8 CELSR2

1.18e-0429973EFO_0004300, EFO_0007796, EFO_0009762
Diseaseautism spectrum disorder (implicated_via_orthology)

TMPRSS9 NLGN4Y CHD7 OPRM1 NLGN4X

1.49e-04152975DOID:0060041 (implicated_via_orthology)
Diseasepemphigus (is_implicated_in)

HLA-DRB1 CD40

2.22e-047972DOID:9182 (is_implicated_in)
Diseasevery low density lipoprotein cholesterol measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2 TNKS2

2.23e-04260976EFO_0008317
DiseaseAutistic Disorder

RELN HLA-DRB1 GRIK2 CSMD3 NLGN4X NPAS2

2.28e-04261976C0004352
Diseasesleep duration, low density lipoprotein cholesterol measurement

TDRD15 ZHX3 IGF2R CELSR2

2.36e-0491974EFO_0004611, EFO_0005271
Diseaseesterified cholesterol measurement, intermediate density lipoprotein measurement

TDRD15 CELSR2

2.96e-048972EFO_0008589, EFO_0008595
DiseaseX-17676 measurement

DNAH3 TAS1R2

2.96e-048972EFO_0800785
Diseaseautistic disorder (is_implicated_in)

RELN HLA-DRB1 NLGN4X

3.60e-0442973DOID:12849 (is_implicated_in)
Diseaselow affinity immunoglobulin epsilon Fc receptor measurement

HLA-DRB1 CD40

3.79e-049972EFO_0008210
DiseasePITUITARY DWARFISM I

POC1A WDR4

3.79e-049972C0342573
DiseaseHMG CoA reductase inhibitor use measurement

TDRD15 ZHX3 CTRB2 CELSR2 CTRB1

4.09e-04189975EFO_0009932
Diseasefamilial hyperlipidemia

TDRD15 HLA-DRB1 IGF2R CELSR2

4.22e-04106974MONDO_0001336
Diseaseinterleukin 7 measurement

CCDC71L PARP8 NPAS2

4.42e-0445973EFO_0008189
Diseaseomega-6 polyunsaturated fatty acid measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2

4.94e-04197975EFO_0005680
Diseasepathological myopia

PARP8 CLSTN2 NAV3 DNAH9

5.02e-04111974EFO_0004207
Diseaselipoprotein A measurement

TDRD15 IGF2R CELSR2 SYTL3

5.19e-04112974EFO_0006925
Diseasetotal lipids in lipoprotein particles measurement

TDRD15 HLA-DRB1 CELSR2

5.35e-0448973EFO_0022309
Diseasefree cholesterol measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

5.37e-04113974EFO_0008591
Diseasetotal cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

5.55e-04114974EFO_0004574, EFO_0004611
Diseasecholesterol in medium LDL measurement

HLA-DRB1 IGF2R CELSR2

5.69e-0449973EFO_0022224
Diseasecholesterol in small LDL measurement

HLA-DRB1 IGF2R CELSR2

5.69e-0449973EFO_0022227
Diseasecholesteryl esters to total lipids in small VLDL percentage

TDRD15 HLA-DRB1 CELSR2

5.69e-0449973EFO_0022256
Diseasetrypsin-2 measurement

CTRB2 CTRB1

5.77e-0411972EFO_0008305
Diseasetotal cholesterol measurement, diastolic blood pressure, triglyceride measurement, systolic blood pressure, hematocrit, ventricular rate measurement, glucose measurement, body mass index, high density lipoprotein cholesterol measurement

TDRD15 ZHX3 CELSR2

6.40e-0451973EFO_0004340, EFO_0004348, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928
Diseasephospholipids in medium VLDL measurement

HLA-DRB1 IGF2R CELSR2

6.77e-0452973EFO_0022154
Diseasetotal lipids in medium LDL

HLA-DRB1 IGF2R CELSR2

6.77e-0452973EFO_0022180
Diseaseage-related hearing impairment

TMPRSS9 NAPEPLD HLA-DRB1 CLSTN2 CSMD3 CPNE1

7.16e-04324976EFO_0005782
Diseasecholesterol in small VLDL measurement

HLA-DRB1 IGF2R CELSR2

7.16e-0453973EFO_0022228
Diseasefree cholesterol measurement, very low density lipoprotein cholesterol measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2

7.34e-04215975EFO_0008317, EFO_0008591
Diseasecholesterol to total lipids in very large VLDL percentage

TDRD15 HLA-DRB1 CELSR2

7.56e-0454973EFO_0022244
Diseasetriglycerides in medium VLDL measurement

TDRD15 HLA-DRB1 CELSR2

7.98e-0455973EFO_0022155
Diseasecholesteryl ester measurement, low density lipoprotein cholesterol measurement

TDRD15 HLA-DRB1 IGF2R CELSR2

8.08e-04126974EFO_0004611, EFO_0010351
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

TDRD15 HLA-DRB1 IGF2R CELSR2 TNKS2

8.82e-04224975EFO_0004530, EFO_0008317
Diseasetotal lipids in large LDL

TDRD15 IGF2R CELSR2

8.86e-0457973EFO_0022163
Diseasecholesterol in large LDL measurement

TDRD15 IGF2R CELSR2

8.86e-0457973EFO_0021901
Diseasediffuse plaque measurement

CCDC71L TMPRSS9 RELN GRIK2 CSMD3 OPRM1 CD40 NAV3 NPAS2

8.87e-04758979EFO_0010699
Diseasecholesteryl ester measurement, very low density lipoprotein cholesterol measurement

TDRD15 ZHX3 HLA-DRB1 IGF2R CELSR2

8.99e-04225975EFO_0008317, EFO_0010351
Diseaseesterified cholesterol measurement, low density lipoprotein cholesterol measurement

TDRD15 CELSR2

9.49e-0414972EFO_0004611, EFO_0008589
Diseasephospholipids in small LDL measurement

TDRD15 IGF2R CELSR2

9.80e-0459973EFO_0022297
Diseasefree cholesterol to total lipids in very large VLDL percentage

TDRD15 HLA-DRB1 CELSR2

9.80e-0459973EFO_0022289
Diseaseresponse to statin, LDL cholesterol change measurement

TDRD15 CELSR2

1.09e-0315972EFO_0007804, GO_0036273
Diseaseserum metabolite measurement

TNPO1 TDRD15 POC1A HLA-DRB1 COL27A1 GRIK2 ZSCAN25 SLC22A24 IGF2R CELSR2

1.10e-039459710EFO_0005653
Diseasecholesterol to total lipids in medium VLDL percentage

TDRD15 HLA-DRB1 CELSR2

1.19e-0363973EFO_0022239
Diseasecholesteryl esters to total lipids in medium VLDL percentage

TDRD15 HLA-DRB1 CELSR2

1.24e-0364973EFO_0022253
Diseasecochlin measurement

CCDC71L G2E3

1.25e-0316972EFO_0801481
Diseasetriglycerides in small LDL measurement

TDRD15 HLA-DRB1 CELSR2

1.30e-0365973EFO_0022323
Diseasecholesterol to total lipids in chylomicrons and extremely large VLDL percentage

TDRD15 CELSR2

1.41e-0317972EFO_0022232
Diseasetotal lipids in large VLDL

TDRD15 HLA-DRB1 CELSR2

1.42e-0367973EFO_0022175
Diseasetriglycerides in very small VLDL measurement

TDRD15 HLA-DRB1 IGF2R

1.48e-0368973EFO_0022144
Diseasefree cholesterol in large VLDL measurement

TDRD15 HLA-DRB1 CELSR2

1.48e-0368973EFO_0022265
Diseasetotal cholesterol measurement, hematocrit, stroke, ventricular rate measurement, body mass index, atrial fibrillation, high density lipoprotein cholesterol measurement, coronary artery disease, diastolic blood pressure, triglyceride measurement, systolic blood pressure, heart failure, diabetes mellitus, glucose measurement, mortality, cancer

TDRD15 ZHX3 CELSR2

1.54e-0369973EFO_0000275, EFO_0000400, EFO_0000712, EFO_0001645, EFO_0003144, EFO_0004340, EFO_0004348, EFO_0004352, EFO_0004468, EFO_0004530, EFO_0004574, EFO_0004612, EFO_0006335, EFO_0006336, EFO_0007928, MONDO_0004992
Diseasevery low density lipoprotein cholesterol measurement, esterified cholesterol measurement

TDRD15 CELSR2

1.58e-0318972EFO_0008317, EFO_0008589
Diseasecholesteryl ester measurement

TDRD15 HLA-DRB1 IGF2R CELSR2 CD40

1.62e-03257975EFO_0010351
Diseaselow density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio

TDRD15 HLA-DRB1 IGF2R CELSR2

1.66e-03153974EFO_0004611, EFO_0020944
Diseaseunipolar depression, response to bupropion, mood disorder

ZHX3 NAV3

1.76e-0319972EFO_0003761, EFO_0004247, EFO_0006326
Diseaseovulation

FAM227A KDM4A

1.76e-0319972GO_0030728
Diseasecolorectal cancer, inflammatory bowel disease

HLA-DRB1 GRIK2

1.76e-0319972EFO_0003767, MONDO_0005575
Diseaserenal system measurement

GRIK2 RGS14

1.96e-0320972EFO_0004742
DiseaseColorectal Carcinoma

DNAH3 VPS18 PARP8 CLSTN2 CORO1B CSMD3 NLGN4X HR

2.22e-03702978C0009402
Diseaseresponse to anticonvulsant

TDRD15 CLSTN2 NAV3

2.80e-0385973GO_0036277
Diseaselipoprotein measurement, phospholipid measurement

TDRD15 HLA-DRB1 CELSR2

2.80e-0385973EFO_0004639, EFO_0004732
DiseaseAutism Spectrum Disorders

RELN NLGN4X USH2A

2.80e-0385973C1510586
Diseasefree cholesterol:total lipids ratio, intermediate density lipoprotein measurement

TDRD15 HLA-DRB1 CELSR2

2.89e-0386973EFO_0008595, EFO_0020945
Diseaseliver fibrosis measurement

CCDC71L TDRD15 CELSR2

2.89e-0386973EFO_0010576
DiseaseDwarfism

POC1A WDR4

3.05e-0325972C0013336
Diseaseserum gamma-glutamyl transferase measurement

TNPO1 SIPA1L3 CSMD3 ARPC1B CELSR2 NBEAL2 WBP4 CPNE1 FAM227A

3.17e-03914979EFO_0004532

Protein segments in the cluster

PeptideGeneStartEntry
PWQVSLQDKTGFHFC

CTRB2

46

Q6GPI1
PQSWFDTHEFKSDIC

FAM227A

261

F5H4B4
KRQEWAEPNSFHVCI

EP400

1181

Q96L91
RGFHCESSAHWPIFK

EIF3B

416

P55884
VRDNCHPFKATVLVW

COX18

161

Q8N8Q8
EVFAAWSDHRPVCKV

CSMD3

531

Q7Z407
FLVEPISCHAWNKDR

ARPC1B

6

O15143
WDSTFCAVNPKFLAV

CORO1B

36

Q9BR76
WVHRFCPQAAFVMKT

B3GALT5

141

Q9Y2C3
TEERTKPICVFWNHS

CELSR2

2311

Q9HCU4
VSFHPCIRFKRWESE

AP3M1

231

Q9Y2T2
AEEAALTCWKTFLHP

DHX32

526

Q7L7V1
TFRPAEFHWKLDQIC

CLSTN2

436

Q9H4D0
HERTFAFSFWPKDRV

CHD7

2301

Q9P2D1
RQCKWFVFDHDLVLP

LRRC9

601

Q6ZRR7
QWNSKPEFIVCTHSV

NPAS2

336

Q99743
VSFHPCVRFKRWESE

AP3M2

231

P53677
AAIASCKRAFPAWAD

ALDH6A1

81

Q02252
LSQHINWVRCAKFSP

POC1A

141

Q8NBT0
NLTRWTFEKACHPFL

TOR1AIP2

76

Q9H496
PETTFQTVSWHFCIA

OPRM1

311

P35372
WVVPNTDHVCTRFFF

PARP8

806

Q8N3A8
QTPREHSWISCKKEF

HHLA3

96

Q9XRX5
WSSLPCTKNRPFDFH

LONRF1

341

Q17RB8
DFTVNLPRFWESHAC

FUT9

321

Q9Y231
KTWLTRHSEQFECPR

HR

381

O43593
RIASPEEWHKVFSTC

OR51F1

236

A6NGY5
AHRFFDIKTWCCTSP

OR52B2

306

Q96RD2
AKVAASDWTFLHCLP

OTC

291

P00480
NFRWVLCANHTEPVK

NAV3

2171

Q8IVL0
NHSLWEPKVFAIRCF

EFR3B

261

Q9Y2G0
TQDPFCEWHQSTSRK

MEGF8

911

Q7Z7M0
DDWPFVVFITCFRHK

KDM4A

871

O75164
PSAAEVFKCVRWMHF

KBTBD7

256

Q8WVZ9
FWRFAAAPHICSDLK

PANX1

126

Q96RD7
NWLFFPGATVKHSCQ

RELN

371

P78509
FIHTKPNRFEEVAWS

NLGN4Y

546

Q8NFZ3
FTGNFASFCWDHRPV

G2E3

116

Q7L622
ENCWEEQTPGFKSHF

CEFIP

1021

Q711Q0
CFAQTVSPAEKWSVH

FSCN1

121

Q16658
PTCAQLFTSRKEHWI

DNAH3

406

Q8TD57
FSVLWNVPSAHCEAR

HYAL3

31

O43820
FLWQPKRECHFFNGT

HLA-DRB1

36

P01911
CKVQDGRWHQTLFTF

COL27A1

1811

Q8IZC6
TFPVTCLVDDWFVHK

MBOAT1

261

Q6ZNC8
CLVDDWFVHKASFPA

MBOAT1

266

Q6ZNC8
VWFDRFKITNDCPEH

LYPLAL1

76

Q5VWZ2
VHNWDFEPRKVSRCS

DEF8

321

Q6ZN54
ELWSFLCSLKHQFSP

CCDC71L

76

Q8N9Z2
SRKFPAIVNCTAIHW

DNAH9

2966

Q9NYC9
TVSSLQCNRHKPWRF

GRIK2

341

Q13002
KAHFWPRDLVAFSAQ

CERCAM

516

Q5T4B2
KTVRFQTPGRFSWFC

CCDC8

476

Q9H0W5
SPSEHRKWVEVFKAC

EFCAB11

16

Q9BUY7
FIHTKPNRFEEVAWS

NLGN4X

546

Q8N0W4
PWQVSLQDKTGFHFC

CTRB1

46

P17538
NPTWKRFSVPVQHFC

CPNE1

186

Q99829
PSAAEVFKCVRWMHF

KBTBD6

256

Q86V97
PRFGDHFEWNKVTSC

OSBPL7

626

Q9BZF2
FCFKLFHPLDQSVWA

OSBPL5

186

Q9H0X9
PSNTVWKIASDCFRF

NXT1

121

Q9UKK6
LFFSWHTPLACEQAT

IGF2R

1636

P11717
QACPQWKHSFVFSGV

SYTL3

526

Q4VX76
FAPWSLHSFRVQACT

USH2A

2296

O75445
DGLFSSHPSKRACFW

UTS2B

101

Q765I0
AIRFHCDPTFWAKNV

TRIM33

456

Q9UPN9
CTVFANDLNPESHKW

TRMT5

321

Q32P41
FERPFKDHQVCLEWN

SEL1L3

211

Q68CR1
TAAHCIFWKDTDPSI

PRSS29P

111

A6NIE9
VLENFTAFTPSHRCW

SLC22A24

36

Q8N4F4
NHFIEPVSCKLFSWT

TDRD15

866

B5MCY1
CLQKHFSRPSIWTQF

RGS20

11

O76081
IEKLCGHANWSQFRF

INSL6

41

Q9Y581
FQAFCATPEWRHFID

NBEAL2

1701

Q6ZNJ1
WIEEKTFCNAFPFHI

GUCY1B2

186

O75343
SRPWVCQKSFAHFDV

SIPA1L3

331

O60292
FSFPHKFEISFVIWC

SLC9A8

371

Q9Y2E8
ATKSRHSVQFVDWCP

TUBAL3

341

A6NHL2
HSVQFVDWCPTGFKV

TUBAL3

346

A6NHL2
VFQSHREFKEWFSNP

SRCAP

796

Q6ZRS2
TTEWPDCAKKRFANH

SVEP1

781

Q4LDE5
PICFKWFQIDAARGH

SLC39A2

26

Q9NP94
AFPIAKDRCVVAAFW

SNED1

91

Q8TER0
HSAEQCASIVFWKPT

CLEC6A

171

Q6EIG7
PCFTRAIEDWSHFVS

TEPP

181

Q6URK8
ERVTWNHFSPCHFLA

PWP1

346

Q13610
EFKDWNPSTARVHCF

WDR47

151

O94967
AWSEHRRHFPNCFFV

XIAP

216

P98170
SWKVFNERCRIHFKP

MIX23

126

Q4VC31
FQSSHRDFCFGPWKL

TIPRL

6

O75663
DEVKTHSSFWKPFQC

ZSCAN25

336

Q6NSZ9
ECFRTFLSSPRHKEW

VPS18

521

Q9P253
CKCWIADNRPSVEFH

WBP4

16

O75554
FWCAQFTAFPNLAKT

ZBED8

516

Q8IZ13
AAHCFNEFQDPTKWV

TMPRSS9

241

Q7Z410
FWKACERFQQIPASD

RGS14

96

O43566
IFFCDAVASWINPKD

TNPO1

841

Q92973
ACVNATDKWAFTPLH

TNKS2

736

Q9H2K2
CFKRQLVFLEWHEAP

TAS1R2

551

Q8TE23
CFSAKDWPQTFEKFH

TRAPPC9

86

Q96Q05
PQKFAASRIAFWCQE

WDR4

241

P57081
CHSGEASFVWNVAKP

ZHX3

131

Q9H4I2
PAGSVHKFTWLFENC

XIRP1

721

Q702N8
FSNVSSAFEKCHPWT

CD40

151

P25942
HDKVTFVFTPSQHWC

NAPEPLD

241

Q6IQ20