Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	protein-macromolecule adaptor activity	SHANK1 TRERF1 SRRT IGF2BP3 ARID1B TIAL1 KDM5A TLE1 MDC1 HGS PRPF6 ZMIZ1 DOT1L BCL9 CRKL HNRNPCL3	6.38e-05	1160	91	16	GO:0030674
GeneOntologyMolecularFunction	molecular adaptor activity	SHANK1 TRERF1 SRRT IGF2BP3 ARID1B TIAL1 KDM5A TLE1 MDC1 HGS OTUD4 PRPF6 ZMIZ1 DOT1L BCL9 CRKL HNRNPCL3	1.19e-04	1356	91	17	GO:0060090
GeneOntologyMolecularFunction	protein-RNA adaptor activity	IGF2BP3 TIAL1 HNRNPCL3	1.73e-04	24	91	3	GO:0140517
GeneOntologyMolecularFunction	transcription coactivator activity	TRERF1 ARID1B KDM5A PRPF6 ZMIZ1 DOT1L BCL9	4.71e-04	303	91	7	GO:0003713
GeneOntologyMolecularFunction	protein domain specific binding	PLSCR4 SHANK1 TCF7L2 RARA LITAF HGS PAX3 PLSCR3 ACVR2A FOXA3 HNRNPCL3 PROX1	6.07e-04	875	91	12	GO:0019904
GeneOntologyMolecularFunction	transcription factor binding	TRERF1 TCF7L2 RARA TLE1 PRPF6 PAX3 DOT1L FOXA3 CRKL TBP PROX1	6.20e-04	753	91	11	GO:0008134
GeneOntologyMolecularFunction	RNA polymerase II transcription regulatory region sequence-specific DNA binding	FOXJ2 SOX7 RHOXF2B TCF7L2 RARA SOX21 LITAF RHOXF2 E2F7 PAX3 PAX7 FOXA3 TCF7L1 FOXI1 TBP PROX1	8.49e-04	1459	91	16	GO:0000977
GeneOntologyBiologicalProcess	positive regulation of transcription by RNA polymerase II	TRERF1 FOXJ2 SOX7 TCF7L2 AGO2 RARA SOX21 LITAF MDC1 E2F7 SSBP2 PRPF6 PAX3 PAX7 ZMIZ1 ACVR2A DOT1L BCL9 FOXA3 TCF7L1 FOXI1 TBP PROX1	1.88e-08	1390	90	23	GO:0045944
GeneOntologyBiologicalProcess	RNA localization	CASC3 IGF2BP3 POM121 SMG7 NOL6 PRPF6 UPF1	4.62e-05	217	90	7	GO:0006403
GeneOntologyBiologicalProcess	RNA export from nucleus	CASC3 POM121 SMG7 NOL6 UPF1	6.32e-05	96	90	5	GO:0006405
GeneOntologyBiologicalProcess	dorsal spinal cord development	PAX3 PAX7 PROX1	1.17e-04	22	90	3	GO:0021516
GeneOntologyBiologicalProcess	RNA transport	CASC3 IGF2BP3 POM121 SMG7 NOL6 UPF1	1.18e-04	175	90	6	GO:0050658
GeneOntologyBiologicalProcess	nucleic acid transport	CASC3 IGF2BP3 POM121 SMG7 NOL6 UPF1	1.18e-04	175	90	6	GO:0050657
GeneOntologyBiologicalProcess	establishment of RNA localization	CASC3 IGF2BP3 POM121 SMG7 NOL6 UPF1	1.30e-04	178	90	6	GO:0051236
GeneOntologyBiologicalProcess	mRNA metabolic process	SRRT CASC3 RC3H2 IGF2BP3 AGO2 RARA SMG7 RNPC3 PRPF6 UPF1 PRPF8 HNRNPCL3 TBP	1.68e-04	917	90	13	GO:0016071
GeneOntologyCellularComponent	beta-catenin-TCF complex	TCF7L2 TLE1 BCL9 TCF7L1	2.33e-07	13	91	4	GO:1990907
GeneOntologyCellularComponent	nuclear protein-containing complex	TRERF1 CASC3 ARID1B TCF7L2 RARA POM121 SMG7 UBAP2L DROSHA AMOT RNPC3 TLE1 NOL6 E2F7 PRPF6 UPF1 BCL9 PRPF8 TCF7L1 HNRNPCL3 TBP	3.45e-07	1377	91	21	GO:0140513
GeneOntologyCellularComponent	cytoplasmic stress granule	CASC3 RC3H2 IGF2BP3 AGO2 TIAL1 UBAP2L	3.90e-06	96	91	6	GO:0010494
GeneOntologyCellularComponent	chromatin	FOXJ2 SOX7 RHOXF2B ARID1B TCF7L2 RARA SOX21 KDM5A RHOXF2 E2F7 PAX3 UPF1 PAX7 ZMIZ1 FOXA3 TCF7L1 FOXI1 TBP PROX1	1.68e-05	1480	91	19	GO:0000785
GeneOntologyCellularComponent	Hrd1p ubiquitin ligase complex	OS9 SYVN1	1.12e-04	4	91	2	GO:0000836
GeneOntologyCellularComponent	cytoplasmic ribonucleoprotein granule	CASC3 RC3H2 IGF2BP3 AGO2 TIAL1 UBAP2L UPF1	1.74e-04	269	91	7	GO:0036464
GeneOntologyCellularComponent	ER ubiquitin ligase complex	OS9 SYVN1	1.86e-04	5	91	2	GO:0000835
GeneOntologyCellularComponent	RNA polymerase II transcription regulator complex	TCF7L2 RARA TLE1 E2F7 BCL9 TCF7L1 TBP	1.86e-04	272	91	7	GO:0090575
GeneOntologyCellularComponent	ribonucleoprotein granule	CASC3 RC3H2 IGF2BP3 AGO2 TIAL1 UBAP2L UPF1	2.59e-04	287	91	7	GO:0035770
GeneOntologyCellularComponent	transcription regulator complex	TRERF1 TCF7L2 RARA TLE1 E2F7 PAX3 PAX7 BCL9 TCF7L1 TBP	2.66e-04	596	91	10	GO:0005667
GeneOntologyCellularComponent	spliceosomal complex	CASC3 RNPC3 PRPF6 UPF1 PRPF8 HNRNPCL3	3.56e-04	215	91	6	GO:0005681
GeneOntologyCellularComponent	P-body	RC3H2 IGF2BP3 AGO2 UPF1	1.03e-03	102	91	4	GO:0000932
GeneOntologyCellularComponent	U2-type catalytic step 1 spliceosome	CASC3 PRPF8	1.65e-03	14	91	2	GO:0071006
GeneOntologyCellularComponent	catalytic step 1 spliceosome	CASC3 PRPF8	1.65e-03	14	91	2	GO:0071012
GeneOntologyCellularComponent	cytoplasmic ubiquitin ligase complex	OS9 SYVN1	1.65e-03	14	91	2	GO:0000153
Domain	HMG_box_dom	SOX7 TCF7L2 SOX21 TCF7L1 PROX1	1.45e-05	65	89	5	IPR009071
Domain	Pax7_C	PAX3 PAX7	2.25e-05	2	89	2	IPR022106
Domain	TBP_CS	TBPL2 TBP	2.25e-05	2	89	2	IPR030491
Domain	TBP_eukaryotic	TBPL2 TBP	2.25e-05	2	89	2	IPR033710
Domain	Pax7	PAX3 PAX7	2.25e-05	2	89	2	PF12360
Domain	TFIID	TBPL2 TBP	6.72e-05	3	89	2	PS00351
Domain	TBP	TBPL2 TBP	6.72e-05	3	89	2	PF00352
Domain	TBP	TBPL2 TBP	6.72e-05	3	89	2	IPR000814
Domain	HMG_box	SOX7 TCF7L2 SOX21 TCF7L1	1.18e-04	53	89	4	PF00505
Domain	HMG_BOX_2	SOX7 TCF7L2 SOX21 TCF7L1	1.27e-04	54	89	4	PS50118
Domain	HMG	SOX7 TCF7L2 SOX21 TCF7L1	1.27e-04	54	89	4	SM00398
Domain	CTNNB1-bd_N	TCF7L2 TCF7L1	1.34e-04	4	89	2	IPR013558
Domain	CTNNB1_binding	TCF7L2 TCF7L1	1.34e-04	4	89	2	PF08347
Domain	TCF/LEF	TCF7L2 TCF7L1	1.34e-04	4	89	2	IPR024940
Domain	-	SOX7 TCF7L2 SOX21 TCF7L1	1.36e-04	55	89	4	1.10.30.10
Domain	Scramblase	PLSCR4 PLSCR3	2.22e-04	5	89	2	PF03803
Domain	Scramblase	PLSCR4 PLSCR3	2.22e-04	5	89	2	IPR005552
Domain	Beta2_adaptin/TBP_C_dom	TBPL2 TBP	3.33e-04	6	89	2	IPR012295
Domain	-	TBPL2 TBP	3.33e-04	6	89	2	3.30.310.10
Domain	-	FOXJ2 E2F7 PAX3 PAX7 FOXA3 FOXI1	6.13e-04	218	89	6	1.10.10.10
Domain	PAX	PAX3 PAX7	7.91e-04	9	89	2	SM00351
Domain	Paired_dom	PAX3 PAX7	7.91e-04	9	89	2	IPR001523
Domain	PAIRED_2	PAX3 PAX7	7.91e-04	9	89	2	PS51057
Domain	PAX	PAX3 PAX7	7.91e-04	9	89	2	PF00292
Domain	PAIRED_1	PAX3 PAX7	7.91e-04	9	89	2	PS00034
Domain	WHTH_DNA-bd_dom	FOXJ2 E2F7 PAX3 PAX7 FOXA3 FOXI1	1.05e-03	242	89	6	IPR011991
Domain	TF_fork_head_CS_2	FOXJ2 FOXA3 FOXI1	1.37e-03	46	89	3	IPR030456
Domain	TF_fork_head_CS_1	FOXJ2 FOXA3 FOXI1	1.46e-03	47	89	3	IPR018122
Domain	FH	FOXJ2 FOXA3 FOXI1	1.64e-03	49	89	3	SM00339
Domain	FORK_HEAD_1	FOXJ2 FOXA3 FOXI1	1.64e-03	49	89	3	PS00657
Domain	FORK_HEAD_2	FOXJ2 FOXA3 FOXI1	1.64e-03	49	89	3	PS00658
Domain	Fork_head_dom	FOXJ2 FOXA3 FOXI1	1.64e-03	49	89	3	IPR001766
Domain	FORK_HEAD_3	FOXJ2 FOXA3 FOXI1	1.64e-03	49	89	3	PS50039
Domain	Forkhead	FOXJ2 FOXA3 FOXI1	1.64e-03	49	89	3	PF00250
Domain	-	ARID1B KDM5A	2.26e-03	15	89	2	1.10.150.60
Domain	BRIGHT	ARID1B KDM5A	2.26e-03	15	89	2	SM00501
Domain	ARID_dom	ARID1B KDM5A	2.26e-03	15	89	2	IPR001606
Domain	ARID	ARID1B KDM5A	2.26e-03	15	89	2	PS51011
Domain	ARID	ARID1B KDM5A	2.26e-03	15	89	2	PF01388
Pathway	REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX	SOX7 TCF7L2 TLE1 BCL9 TCF7L1	1.23e-06	42	64	5	M27272
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	TCF7L2 TLE1 BCL9 TCF7L1	5.36e-06	26	64	4	MM14793
Pathway	REACTOME_REPRESSION_OF_WNT_TARGET_GENES	TCF7L2 TLE1 TCF7L1	1.05e-05	10	64	3	MM15156
Pathway	REACTOME_DEACTIVATION_OF_THE_BETA_CATENIN_TRANSACTIVATING_COMPLEX	SOX7 TCF7L2 TLE1 TCF7L1	1.26e-05	32	64	4	MM14975
Pathway	WP_INFLUENCE_OF_LAMINOPATHIES_ON_WNT_SIGNALING	TCF7L2 AGO2 TLE1 TCF7L1	2.28e-05	37	64	4	M39817
Pathway	REACTOME_REPRESSION_OF_WNT_TARGET_GENES	TCF7L2 TLE1 TCF7L1	3.13e-05	14	64	3	M27402
Pathway	REACTOME_SPECIFICATION_OF_THE_NEURAL_PLATE_BORDER	PAX3 PAX7 TCF7L1	5.80e-05	17	64	3	M48248
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	USP34 SOX7 TCF7L2 TLE1 BCL9 TCF7L1	7.90e-05	158	64	6	MM14791
Pathway	WP_OVERLAP_BETWEEN_SIGNAL_TRANSDUCTION_PATHWAYS_CONTRIBUTING_TO_LMNA_LAMINOPATHIES	TCF7L2 AGO2 TLE1 TCF7L1	1.27e-04	57	64	4	M39877
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	SRRT CASC3 POM121 RNPC3 PRPF6 PRPF8 HNRNPCL3	2.50e-04	277	64	7	MM15414
Pathway	REACTOME_GASTRULATION	TBPL2 TCF7L2 PAX3 PAX7 TCF7L1	2.94e-04	129	64	5	M46433
Pathway	REACTOME_MRNA_SPLICING	SRRT CASC3 RNPC3 PRPF6 PRPF8 HNRNPCL3	2.94e-04	201	64	6	MM15411
Pathway	BIOCARTA_RARRXR_PATHWAY	RARA TBP	3.01e-04	6	64	2	MM1447
Pathway	WP_EXRNA_MECHANISM_OF_ACTION_AND_BIOGENESIS	AGO2 DROSHA	3.01e-04	6	64	2	M39578
Pathway	REACTOME_RUNX3_REGULATES_WNT_SIGNALING	TCF7L2 TCF7L1	3.01e-04	6	64	2	MM15542
Pathway	KEGG_MEDICUS_PATHOGEN_SALMONELLA_AVRA_TO_BETA_CATENIN_SIGNALING_PATHWAY	TCF7L2 TCF7L1	3.01e-04	6	64	2	M47736
Pathway	REACTOME_MITF_M_REGULATED_MELANOCYTE_DEVELOPMENT	ARID1B TCF7L2 AGO2 PAX3 TCF7L1	3.88e-04	137	64	5	M48232
Pathway	REACTOME_METABOLISM_OF_RNA	SRRT CASC3 POM121 SMG7 RNPC3 NOL6 PRPF6 UPF1 PRPF8 HNRNPCL3	4.02e-04	612	64	10	MM15547
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_LANA_TO_WNT_SIGNALING_PATHWAY	TCF7L2 TCF7L1	4.20e-04	7	64	2	M47465
Pathway	BIOCARTA_RARRXR_PATHWAY	RARA TBP	4.20e-04	7	64	2	M6907
Pathway	PID_BETA_CATENIN_NUC_PATHWAY	TCF7L2 TLE1 BCL9 TCF7L1	4.72e-04	80	64	4	M223
Pathway	WP_ENDODERM_DIFFERENTIATION	TRERF1 SOX7 SOX21 PAX3 TCF7L1	4.72e-04	143	64	5	M39591
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION	TCF7L2 TCF7L1	5.58e-04	8	64	2	MM17229
Pathway	REACTOME_BINDING_OF_TCF_LEF_CTNNB1_TO_TARGET_GENE_PROMOTERS	TCF7L2 TCF7L1	5.58e-04	8	64	2	M27359
Pathway	KEGG_MEDICUS_VARIANT_CDH1_REDUCED_EXPRESSION_TO_BETA_CATENIN_SIGNALING_PATHWAY	TCF7L2 TCF7L1	5.58e-04	8	64	2	M47413
Pathway	REACTOME_RUNX3_REGULATES_WNT_SIGNALING	TCF7L2 TCF7L1	5.58e-04	8	64	2	M27821
Pathway	REACTOME_TCF_DEPENDENT_SIGNALING_IN_RESPONSE_TO_WNT	USP34 SOX7 TCF7L2 TLE1 BCL9 TCF7L1	6.44e-04	233	64	6	M27099
Pathway	REACTOME_SIGNALING_BY_WNT	USP34 SOX7 TCF7L2 AGO2 TLE1 BCL9 TCF7L1	7.15e-04	330	64	7	M7847
Pathway	REACTOME_SIGNALING_BY_WNT	USP34 SOX7 TCF7L2 TLE1 BCL9 TCF7L1	7.36e-04	239	64	6	MM14756
Pathway	REACTOME_FORMATION_OF_THE_BETA_CATENIN_TCF_TRANSACTIVATING_COMPLEX	TCF7L2 TLE1 BCL9 TCF7L1	7.68e-04	91	64	4	M27101
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_AXIN_TO_WNT_SIGNALING_PATHWAY	TCF7L2 TCF7L1	8.92e-04	10	64	2	M47486
Pathway	REACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION	ARID1B TCF7L2 AGO2 TCF7L1	9.03e-04	95	64	4	M48268
Pathway	KEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_APC_TO_WNT_SIGNALING_PATHWAY	TCF7L2 TCF7L1	1.30e-03	12	64	2	M47410
Pathway	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	RNPC3 PRPF6 PRPF8	1.33e-03	48	64	3	MM15410
Pathway	REACTOME_SIGNALING_BY_TGFBR3	AGO2 RARA ACVR2A	1.42e-03	49	64	3	M48250
Pathway	REACTOME_METABOLISM_OF_RNA	SRRT CASC3 IGF2BP3 POM121 SMG7 RNPC3 NOL6 PRPF6 UPF1 PRPF8	1.47e-03	724	64	10	M16843
Pathway	REACTOME_MRNA_SPLICING_MINOR_PATHWAY	RNPC3 PRPF6 PRPF8	1.50e-03	50	64	3	M5583
Pathway	REACTOME_PROCESSING_OF_CAPPED_INTRON_CONTAINING_PRE_MRNA	SRRT CASC3 POM121 RNPC3 PRPF6 PRPF8	1.75e-03	283	64	6	M13087
Pathway	KEGG_ACUTE_MYELOID_LEUKEMIA	TCF7L2 RARA TCF7L1	2.19e-03	57	64	3	M19888
Pathway	REACTOME_MITF_M_DEPENDENT_GENE_EXPRESSION	TCF7L2 TCF7L1	2.34e-03	16	64	2	MM17241
Pathway	BIOCARTA_PML_PATHWAY	RARA PAX3	2.64e-03	17	64	2	M4891
Pathway	WP_AMPLIFICATION_AND_EXPANSION_OF_ONCOGENIC_PATHWAYS_AS_METASTATIC_TRAITS	TCF7L2 TCF7L1	2.64e-03	17	64	2	M39443
Pathway	REACTOME_REGULATION_OF_MITF_M_DEPENDENT_GENES_INVOLVED_IN_CELL_CYCLE_AND_PROLIFERATION	TCF7L2 TCF7L1	2.64e-03	17	64	2	M48240
Pathway	REACTOME_MRNA_SPLICING	SRRT CASC3 RNPC3 PRPF6 PRPF8	2.72e-03	212	64	5	M14033
Pathway	REACTOME_CA2_PATHWAY	TCF7L2 AGO2 TCF7L1	2.79e-03	62	64	3	M27321
Pathway	WP_22Q112_COPY_NUMBER_VARIATION_SYNDROME	DROSHA CYP26A1 PAX3 CRKL	2.86e-03	130	64	4	M39787
Pathway	WP_PATHOPHYSIOLOGICAL_ROLES_OF_DUX4_IN_FSHD1	UPF1 PAX7	2.96e-03	18	64	2	M48069
Pathway	BIOCARTA_PML_PATHWAY	RARA PAX3	2.96e-03	18	64	2	MM1474
Pubmed	Human transcription factor protein interaction networks.	TRERF1 SRRT IGF2BP3 ARID1B CAD TCF7L2 AGO2 SMG7 KDM5A UBAP2L TLE1 MDC1 HGS OTUD4 SSBP2 UPF1 PAX7 ZMIZ1 DOT1L BCL9 PRRC2A FOXI1 TBP	1.58e-12	1429	91	23	35140242
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	FOXJ2 SOX7 RHOXF2B TCF7L2 RARA RHOXF2 PAX3 PAX7 TCF7L1 PROX1	1.93e-09	263	91	10	20932939
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	ARID1B CAD PTPN13 AGO2 SMG7 UBAP2L PHF3 AMOT MDC1 UPF1 DOT1L PRRC2A CRKL	2.05e-09	549	91	13	38280479
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	PCED1B VPS37C SRRT IGF2BP3 ARID1B CAD PTPN13 NUMBL KDM5A DROSHA RNPC3 ZNF207 SSBP2 PRPF6 UPF1 PRPF8 PROX1	2.79e-09	1082	91	17	38697112
Pubmed	Connective tissue fibroblasts and Tcf4 regulate myogenesis.	TCF7L2 PAX3 PAX7 TCF7L1	3.04e-09	8	91	4	21177349
Pubmed	The variant Polycomb Repressor Complex 1 component PCGF1 interacts with a pluripotency sub-network that includes DPPA4, a regulator of embryogenesis.	TRERF1 USP34 SRRT ARID1B CAD SOX21 TIAL1 MDC1 UPF1 ZMIZ1 TCF7L1	7.61e-09	396	91	11	26687479
Pubmed	A census of human transcription factors: function, expression and evolution.	TRERF1 FOXJ2 SOX7 RC3H2 TCF7L2 RARA SOX21 RHOXF2 E2F7 PAX3 PAX7 FOXA3 TCF7L1 FOXI1 PROX1	1.38e-08	908	91	15	19274049
Pubmed	The mRNA repressor TRIM71 cooperates with Nonsense-Mediated Decay factors to destabilize the mRNA of CDKN1A/p21.	AGO2 SMG7 E2F7 UPF1	2.14e-08	12	91	4	31732746
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SRRT ARID1B CAD POM121 UBAP2L PHF3 AMOT MDC1 NOL6 PRPF6 UPF1	2.24e-08	440	91	11	34244565
Pubmed	Comparative Application of BioID and TurboID for Protein-Proximity Biotinylation.	USP34 ARID1B TCF7L2 POM121 SMG7 TLE1 FAM222B ZNF207 FNDC3A ZMIZ1 BCL9	3.29e-08	457	91	11	32344865
Pubmed	New roles for the de-ubiquitylating enzyme OTUD4 in an RNA-protein network and RNA granules.	SHANK1 CASC3 IGF2BP3 AGO2 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A CRKL HNRNPCL3	3.68e-08	462	91	11	31138677
Pubmed	A genome-wide screen to identify transcription factors expressed in pelvic Ganglia of the lower urinary tract.	FOXJ2 SOX7 RHOXF2B TCF7L2 RARA SOX21 RHOXF2 ZNF207 PAX3 PAX7 ZDHHC3 TCF7L1 PROX1	4.20e-08	709	91	13	22988430
Pubmed	A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.	RC3H2 IGF2BP3 PTPN13 AGO2 SMG7 KDM5A UBAP2L PHF3 AMOT OTUD4 UPF1 PRPF8 PRRC2A	5.35e-08	724	91	13	36232890
Pubmed	A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.	COL8A1 RARA POM121 NUMBL UBAP2L RHOXF2 HGS KLHL42 SYVN1 ZDHHC3 PRRC2A TBP	6.57e-08	608	91	12	16713569
Pubmed	MOV10 Helicase Interacts with Coronavirus Nucleocapsid Protein and Has Antiviral Activity.	AGO2 TIAL1 UPF1	6.92e-08	4	91	3	34517762
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	RC3H2 IGF2BP3 CAD AGO2 POM121 TIAL1 CNTRL MDC1 NOL6 FNDC3A COL22A1 UPF1 PRPF8	8.56e-08	754	91	13	35906200
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	SRRT CASC3 RC3H2 IGF2BP3 AGO2 TIAL1 KDM5A UBAP2L PHF3 DROSHA NOL6 OTUD4 ZNF207 PRPF6 UPF1 PRPF8 PRRC2A	8.83e-08	1371	91	17	36244648
Pubmed	Characterizing WW domain interactions of tumor suppressor WWOX reveals its association with multiprotein networks.	IGF2BP3 CAD RARA DROSHA AMOT BCL9 PRPF8 PRRC2A	1.22e-07	220	91	8	24550385
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	SRRT CASC3 RC3H2 IGF2BP3 AGO2 TIAL1 UBAP2L DROSHA OTUD4 ZNF207 UPF1 PRPF8 PRRC2A	1.86e-07	807	91	13	22681889
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	FOXJ2 SOX7 RARA RHOXF2 E2F7 PAX3 PAX7 FOXA3 TCF7L1 FOXI1 PROX1	1.90e-07	544	91	11	28473536
Pubmed	Integrative genomics positions MKRN1 as a novel ribonucleoprotein within the embryonic stem cell gene regulatory network.	SRRT CASC3 IGF2BP3 AGO2 UPF1	2.59e-07	52	91	5	26265008
Pubmed	Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.	SRRT CASC3 IGF2BP3 CAD UBAP2L DROSHA NOL6 PRPF6 UPF1 PRPF8 PRRC2A HNRNPCL3	3.67e-07	714	91	12	28302793
Pubmed	Interaction network of human early embryonic transcription factors.	TRERF1 ARID1B TCF7L2 KDM5A TLE1 MDC1 SSBP2 ZMIZ1 BCL9	3.71e-07	351	91	9	38297188
Pubmed	mTORC1 activity regulates post-translational modifications of glycine decarboxylase to modulate glycine metabolism and tumorigenesis.	SRRT IGF2BP3 CAD AGO2 UBAP2L AMOT UPF1 PRRC2A	6.47e-07	274	91	8	34244482
Pubmed	Molecular Characterization of the Oncogene BTF3 and Its Targets in Colorectal Cancer.	IGF2BP3 CAD TCF7L2 UBAP2L ZNF207 PRPF6 UPF1 PRPF8 TCF7L1 TBP PROX1	7.58e-07	626	91	11	33644029
Pubmed	RNF138 inhibits late inflammatory gene transcription through degradation of SMARCC1 of the SWI/SNF complex.	ARID1B CAD UBAP2L UPF1	9.91e-07	29	91	4	36800290
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FSIP2 SRRT IGF2BP3 UBAP2L AMOT MDC1 ZNF207 PRRC2A CRKL	1.08e-06	399	91	9	35987950
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP34 IGF2BP3 CAD UBAP2L PHF3 MDC1 NOL6 PRPF6 UPF1 PRPF8 PRRC2A	1.14e-06	653	91	11	22586326
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	SRRT ARID1B RARA TIAL1 UBAP2L PHF3 MDC1 NOL6 ZNF207 PRPF6 PRPF8 PRRC2A HNRNPCL3	1.22e-06	954	91	13	36373674
Pubmed	Resolution of cell fate decisions revealed by single-cell gene expression analysis from zygote to blastocyst.	TRERF1 FOXJ2 SOX7 TCF7L2 RARA SOX21 KDM5A KLHL42 ZNF207 ZDHHC3 TCF7L1 TBP	1.34e-06	808	91	12	20412781
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	SHANK1 TRERF1 CASC3 CAD AGO2 NUMBL KDM5A UBAP2L OTUD4 UPF1 BCL9 PRRC2A PROX1	1.35e-06	963	91	13	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	TRERF1 USP34 PTPN13 KDM5A AMOT TLE1 ZMIZ1 CRKL PROX1	1.58e-06	418	91	9	34709266
Pubmed	The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.	SRRT CASC3 CAD PTPN13 TIAL1 NUMBL KDM5A PHF3 DROSHA MDC1 NOL6 OTUD4 ZNF207 OS9 PRRC2A TBP	1.58e-06	1497	91	16	31527615
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	RC3H2 IGF2BP3 CAD AGO2 SMG7 UBAP2L NOL6 OTUD4 UPF1 PRPF8 PRRC2A	1.64e-06	678	91	11	30209976
Pubmed	Loss of TRIM31 promotes breast cancer progression through regulating K48- and K63-linked ubiquitination of p53.	RC3H2 IGF2BP3 CAD AGO2 TIAL1 UBAP2L ZNF207 UPF1 PRPF8	1.67e-06	421	91	9	34650049
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	SRRT IGF2BP3 CAD UBAP2L E2F7 OTUD4 PRPF6 UPF1 PRPF8 PRRC2A	1.87e-06	551	91	10	34728620
Pubmed	Development of a subset of forelimb muscles and their attachment sites requires the ulnar-mammary syndrome gene Tbx3.	TCF7L2 PAX3 PAX7	2.05e-06	10	91	3	27491074
Pubmed	Muscle connective tissue controls development of the diaphragm and is a source of congenital diaphragmatic hernias.	TCF7L2 PAX3 PAX7	2.05e-06	10	91	3	25807280
Pubmed	Elucidation of the BMI1 interactome identifies novel regulatory roles in glioblastoma.	SRRT IGF2BP3 CASKIN2 ZNF207 PRPF6 UPF1 PRPF8 PRRC2A	2.53e-06	329	91	8	34316702
Pubmed	The RNA-binding protein ARPP21 controls dendritic branching by functionally opposing the miRNA it hosts.	CASC3 ARPP21 UPF1	2.82e-06	11	91	3	29581509
Pubmed	The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.	SRRT CAD PHF3 HGS NOL6 E2F7 OTUD4 PRPF6 PAX3 PRPF8	3.09e-06	583	91	10	29844126
Pubmed	RC3H1 post-transcriptionally regulates A20 mRNA and modulates the activity of the IKK/NF-κB pathway.	RC3H2 CAD UBAP2L E2F7 OTUD4 PRPF6	3.60e-06	156	91	6	26170170
Pubmed	Paraxial Mesoderm Is the Major Source of Lymphatic Endothelium.	PAX3 PAX7 PROX1	3.75e-06	12	91	3	31130354
Pubmed	Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1.	TCF7L2 TCF7L1 PROX1	3.75e-06	12	91	3	10631168
Pubmed	HOXA5 protein expression and genetic fate mapping show lineage restriction in the developing musculoskeletal system.	TCF7L2 PAX3 PAX7	3.75e-06	12	91	3	30604848
Pubmed	All Tcf HMG box transcription factors interact with Groucho-related co-repressors.	TCF7L2 TLE1 TCF7L1	3.75e-06	12	91	3	11266540
Pubmed	MKRN2 Physically Interacts with GLE1 to Regulate mRNA Export and Zebrafish Retinal Development.	SRRT RC3H2 CAD TIAL1 MDC1 UPF1 PRPF8 PROX1	4.71e-06	358	91	8	32460013
Pubmed	The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.	SRRT IGF2BP3 UBAP2L PHF3 DROSHA RNPC3 NOL6 PRPF6 UPF1 PRPF8 PRRC2A	4.83e-06	759	91	11	35915203
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	VPS37C SRRT CASC3 IGF2BP3 ARID1B CAD PTPN13 AMOT TLE1 UPF1 PRPF8 PRRC2A	5.19e-06	922	91	12	27609421
Pubmed	TRIM65 regulates microRNA activity by ubiquitination of TNRC6.	KLHL29 SRRT IGF2BP3 AGO2 DROSHA NOL6 PRPF6 UPF1	5.32e-06	364	91	8	24778252
Pubmed	SND1 binds SARS-CoV-2 negative-sense RNA and promotes viral RNA synthesis through NSP9.	SRRT IGF2BP3 TIAL1 UBAP2L UPF1 PRRC2A HNRNPCL3	5.43e-06	258	91	7	37794589
Pubmed	A non-proteolytic role for ubiquitin in deadenylation of MHC-I mRNA by the RNA-binding E3-ligase MEX-3C.	CAD NOL6 PRPF6 PRPF8	5.49e-06	44	91	4	26471122
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	PTPN13 POM121 SMG7 CASKIN2 AMOT HGS PLSCR3	6.15e-06	263	91	7	34702444
Pubmed	Rescue of deficits by Brwd1 copy number restoration in the Ts65Dn mouse model of Down syndrome.	ARID1B TBP BRWD1	6.18e-06	14	91	3	36289231
Pubmed	Wnt3a-/--like phenotype and limb deficiency in Lef1(-/-)Tcf1(-/-) mice.	TCF7L2 PAX3 TCF7L1	6.18e-06	14	91	3	10090727
Pubmed	Aberrant PAX3 and PAX7 expression. A link to the metastatic potential of embryonal rhabdomyosarcoma and cutaneous malignant melanoma?	PAX3 PAX7	6.77e-06	2	91	2	12647804
Pubmed	Variation in the methylation profile and structure of Pax3 and Pax7 among different mouse strains and during expression.	PAX3 PAX7	6.77e-06	2	91	2	9016952
Pubmed	SOX7 Is Required for Muscle Satellite Cell Development and Maintenance.	SOX7 PAX3	6.77e-06	2	91	2	28943254
Pubmed	Cloning and characterization of Ehox, a novel homeobox gene essential for embryonic stem cell differentiation.	RHOXF2B RHOXF2	6.77e-06	2	91	2	12087094
Pubmed	Restricted high level expression of Tcf-4 protein in intestinal and mammary gland epithelium.	TCF7L2 TCF7L1	6.77e-06	2	91	2	9916915
Pubmed	Notch Signaling Rescues Loss of Satellite Cells Lacking Pax7 and Promotes Brown Adipogenic Differentiation.	PAX3 PAX7	6.77e-06	2	91	2	27346341
Pubmed	Comparison of the proximal promoter regions of the PAX3 and PAX7 genes.	PAX3 PAX7	6.77e-06	2	91	2	17954266
Pubmed	A gene family of HMG-box transcription factors with homology to TCF-1.	TCF7L2 TCF7L1	6.77e-06	2	91	2	1741298
Pubmed	Alternate PAX3 and PAX7 C-terminal isoforms in myogenic differentiation and sarcomagenesis.	PAX3 PAX7	6.77e-06	2	91	2	21421465
Pubmed	Rhox homeobox gene cluster: recent duplication of three family members.	RHOXF2B RHOXF2	6.77e-06	2	91	2	16496311
Pubmed	Integrated functions of Pax3 and Pax7 in the regulation of proliferation, cell size and myogenic differentiation.	PAX3 PAX7	6.77e-06	2	91	2	19221588
Pubmed	An alternative splicing event in the Pax-3 paired domain identifies the linker region as a key determinant of paired domain DNA-binding activity.	PAX3 PAX7	6.77e-06	2	91	2	8943322
Pubmed	RNAi inhibition of Pax3/7 expression leads to markedly decreased expression of muscle determination genes.	PAX3 PAX7	6.77e-06	2	91	2	17396232
Pubmed	Pax3 and Pax7 have distinct and overlapping functions in adult muscle progenitor cells.	PAX3 PAX7	6.77e-06	2	91	2	16380438
Pubmed	Identification of a tandem duplicated array in the Rhox alpha locus on mouse chromosome X.	RHOXF2B RHOXF2	6.77e-06	2	91	2	16465597
Pubmed	Cloning and characterization of the 5'-flanking region of the Ehox gene.	RHOXF2B RHOXF2	6.77e-06	2	91	2	16414020
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	TRERF1 ARID1B PHF3 TLE1 MDC1 SSBP2 BCL9	6.95e-06	268	91	7	33640491
Pubmed	A genome-wide screen for spatially restricted expression patterns identifies transcription factors that regulate glial development.	TCF7L2 SOX21 PAX3 PAX7 TCF7L1	7.48e-06	102	91	5	19741146
Pubmed	SOXF factors regulate murine satellite cell self-renewal and function through inhibition of β-catenin activity.	SOX7 PAX3 PAX7	7.71e-06	15	91	3	29882512
Pubmed	Understanding abnormal retinoid signaling as a causative mechanism in congenital diaphragmatic hernia.	RARA PAX3 PAX7	7.71e-06	15	91	3	19448158
Pubmed	Identification and functional characterization of transcriptional activators in human cells.	SOX7 RC3H2 ARID1B TCF7L2 SOX21 TLE1 E2F7 DOT1L	1.02e-05	398	91	8	35016035
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	USP34 ARID1B AGO2 SMG7 CASKIN2 AMOT MDC1 KLHL42 FNDC3A	1.06e-05	529	91	9	14621295
Pubmed	Selective translational repression of truncated proteins from frameshift mutation-derived mRNAs in tumors.	TCF7L2 UPF1 ACVR2A	1.15e-05	17	91	3	17456004
Pubmed	Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.	IGF2BP3 TIAL1 PHF3 DROSHA MDC1 NOL6 PRPF6 UPF1 DOT1L PRPF8 PRRC2A	1.35e-05	847	91	11	35850772
Pubmed	The RNA-binding ubiquitin ligase MKRN1 functions in ribosome-associated quality control of poly(A) translation.	IGF2BP3 AGO2 TIAL1 UPF1	1.35e-05	55	91	4	31640799
Pubmed	The RNA helicase DHX34 activates NMD by promoting a transition from the surveillance to the decay-inducing complex.	CASC3 SMG7 UPF1	1.37e-05	18	91	3	25220460
Pubmed	A Cranial Mesoderm Origin for Esophagus Striated Muscles.	TCF7L2 PAX3 PAX7	1.37e-05	18	91	3	26387456
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	SRRT IGF2BP3 CAD POM121 TIAL1 UBAP2L AMOT MDC1 NOL6 PRPF6 PRPF8 CRKL	1.48e-05	1024	91	12	24711643
Pubmed	C16orf72/HAPSTR1 is a molecular rheostat in an integrated network of stress response pathways.	SRRT IGF2BP3 OTUD4 PRPF6 PRRC2A	1.58e-05	119	91	5	35776542
Pubmed	Muscle composition is regulated by a Lox-TGFβ feedback loop.	TCF7L2 PAX3 PAX7	1.63e-05	19	91	3	25715398
Pubmed	Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.	TRERF1 TCF7L2 POM121 LITAF MDC1 PAX7 BCL9 FOXI1	1.78e-05	430	91	8	35044719
Pubmed	The USP10-HDAC6 axis confers cisplatin resistance in non-small cell lung cancer lacking wild-type p53.	IGF2BP3 CAD OTUD4 UPF1	1.79e-05	59	91	4	32382008
Pubmed	Cold-inducible RBM3 inhibits PERK phosphorylation through cooperation with NF90 to protect cells from endoplasmic reticulum stress.	USP34 CASC3 IGF2BP3 UPF1	1.91e-05	60	91	4	26472337
Pubmed	Barhl2 Determines the Early Patterning of the Diencephalon by Regulating Shh.	PAX3 PAX7 PROX1	1.91e-05	20	91	3	27349434
Pubmed	Odd skipped-related 1 identifies a population of embryonic fibro-adipogenic progenitors regulating myogenesis during limb development.	TCF7L2 PAX3 PAX7	1.91e-05	20	91	3	29084951
Pubmed	ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure.	SRRT IGF2BP3 AGO2 TIAL1 UBAP2L UPF1 PRRC2A	1.98e-05	315	91	7	26777405
Pubmed	Transcriptional modulation of the anti-apoptotic protein BCL-XL by the paired box transcription factors PAX3 and PAX3/FKHR.	PAX3 PAX7	2.03e-05	3	91	2	10871843
Pubmed	Abnormal expression of ER quality control and ER associated degradation proteins in the dorsolateral prefrontal cortex in schizophrenia.	OS9 SYVN1	2.03e-05	3	91	2	29496332
Pubmed	Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling.	TCF7L2 TCF7L1	2.03e-05	3	91	2	17607356
Pubmed	A highly conserved Wnt-dependent TCF4 binding site within the proximal enhancer of the anti-myogenic Msx1 gene supports expression within Pax3-expressing limb bud muscle precursor cells.	TCF7L2 PAX3	2.03e-05	3	91	2	17727834
Pubmed	MicroRNA binding to the HIV-1 Gag protein inhibits Gag assembly and virus production.	AGO2 DROSHA	2.03e-05	3	91	2	24938790
Pubmed	Pax3 functions in cell survival and in pax7 regulation.	PAX3 PAX7	2.03e-05	3	91	2	10079229
Pubmed	SEL1L protein critically determines the stability of the HRD1-SEL1L endoplasmic reticulum-associated degradation (ERAD) complex to optimize the degradation kinetics of ERAD substrates.	OS9 SYVN1	2.03e-05	3	91	2	21454652
Pubmed	PAX3/7-FOXO1 fusion status in older rhabdomyosarcoma patient population by fluorescent in situ hybridization.	PAX3 PAX7	2.03e-05	3	91	2	22089931
Pubmed	A dynamic exchange of TCF3 and TCF4 transcription factors controls MYC expression in colorectal cancer cells.	TCF7L2 TCF7L1	2.03e-05	3	91	2	25659031
Interaction	TLE3 interactions	TRERF1 FOXJ2 SRRT SOX7 ARID1B TCF7L2 POM121 SMG7 TLE1 OTUD4 ZNF207 PAX7 ZMIZ1 DOT1L BCL9 FOXA3 FOXI1	7.59e-13	376	90	17	int:TLE3
Interaction	KRTAP19-7 interactions	PLSCR4 VPS37C COL8A1 TCF7L2 MAPK1IP1L RHOXF2 OTUD4 PLSCR3 PAX7 FOXI1	1.14e-10	117	90	10	int:KRTAP19-7
Interaction	ALG13 interactions	PLSCR4 RC3H2 ARID1B TCF7L2 SMG7 UBAP2L TLE1 OTUD4 UPF1 BCL9 PRRC2A	5.71e-10	183	90	11	int:ALG13
Interaction	DAZAP2 interactions	PLSCR4 VPS37C TCF7L2 TIAL1 LITAF MAPK1IP1L TLE1 RHOXF2 HGS KLHL42 TCF7L1	6.79e-10	186	90	11	int:DAZAP2
Interaction	DAZL interactions	CASC3 RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	9.52e-10	145	90	10	int:DAZL
Interaction	RBMS1 interactions	CASC3 RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L OTUD4 FNDC3A UPF1 PRRC2A	2.11e-09	207	90	11	int:RBMS1
Interaction	EWSR1 interactions	SRRT CASC3 SOX7 RC3H2 CAD TCF7L2 RARA SOX21 UBAP2L AMOT MAPK1IP1L RHOXF2 MDC1 ZNF207 SSBP2 PRPF6 UPF1 BCL9 ZDHHC3 PRRC2A	2.38e-09	906	90	20	int:EWSR1
Interaction	MEX3B interactions	VPS37C CASC3 RC3H2 IGF2BP3 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRPF8 PRRC2A	4.39e-09	222	90	11	int:MEX3B
Interaction	R3HDM2 interactions	CASC3 RC3H2 ARPP21 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	6.21e-09	129	90	9	int:R3HDM2
Interaction	FAM168B interactions	VPS37C TCF7L2 POM121 TIAL1 RHOXF2 FAM222B FOXI1	6.98e-09	58	90	7	int:FAM168B
Interaction	SMAP2 interactions	RC3H2 AGO2 SMG7 NUMBL UBAP2L HGS OTUD4 UPF1 SYVN1 PRRC2A	1.24e-08	189	90	10	int:SMAP2
Interaction	SMG7 interactions	RC3H2 ARID1B AGO2 SMG7 UBAP2L AMOT TLE1 OTUD4 UPF1 DOT1L BCL9 PRRC2A	1.83e-08	319	90	12	int:SMG7
Interaction	RBM47 interactions	CASC3 RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	2.56e-08	204	90	10	int:RBM47
Interaction	PUM1 interactions	RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L LITAF OTUD4 UPF1 DOT1L PRRC2A	6.20e-08	287	90	11	int:PUM1
Interaction	FMR1 interactions	CASC3 RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 NUMBL KDM5A UBAP2L OTUD4 UPF1 DOT1L BCL9 PRRC2A	1.06e-07	536	90	14	int:FMR1
Interaction	PRRC2A interactions	CASC3 RC3H2 COL8A1 AGO2 MAN2C1 SMG7 TIAL1 UBAP2L OTUD4 UPF1 DOT1L PRRC2A	1.60e-07	389	90	12	int:PRRC2A
Interaction	FOXI1 interactions	VPS37C ARID1B TCF7L2 TLE1 HGS BCL9 FOXI1	1.80e-07	92	90	7	int:FOXI1
Interaction	LSM14A interactions	RC3H2 COL8A1 IGF2BP3 AGO2 SMG7 UBAP2L OTUD4 UPF1 DOT1L PRRC2A	2.48e-07	260	90	10	int:LSM14A
Interaction	UPF1 interactions	CASC3 RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L RHOXF2 CNTRL E2F7 OTUD4 UPF1 DOT1L PRRC2A	2.83e-07	581	90	14	int:UPF1
Interaction	KRTAP19-5 interactions	PLSCR4 VPS37C COL8A1 TCF7L2 MAPK1IP1L RHOXF2 HGS	2.98e-07	99	90	7	int:KRTAP19-5
Interaction	PCGF1 interactions	USP34 SRRT ARID1B TIAL1 MDC1 OTUD4 UPF1 PAX7 FOXI1	3.83e-07	208	90	9	int:PCGF1
Interaction	KRTAP6-1 interactions	PLSCR4 VPS37C TCF7L2 MAPK1IP1L RHOXF2 OTUD4 PLSCR3	3.91e-07	103	90	7	int:KRTAP6-1
Interaction	CPEB4 interactions	RC3H2 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	4.88e-07	156	90	8	int:CPEB4
Interaction	G3BP2 interactions	RC3H2 IGF2BP3 CAD AGO2 POM121 UBAP2L HGS NOL6 OTUD4 UPF1 DOT1L PRPF8 PRRC2A	4.97e-07	518	90	13	int:G3BP2
Interaction	IGF2BP2 interactions	RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L CNTRL OTUD4 UPF1 DOT1L PRRC2A	5.51e-07	357	90	11	int:IGF2BP2
Interaction	WWOX interactions	VPS37C IGF2BP3 CAD RARA LITAF DROSHA AMOT FAM222B UPF1 PLSCR3 BCL9 PRPF8 PRRC2A FOXI1	7.04e-07	627	90	14	int:WWOX
Interaction	FUBP3 interactions	RC3H2 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 DOT1L FOXA3 PRRC2A	8.40e-07	297	90	10	int:FUBP3
Interaction	TBXT interactions	ARID1B CAD TCF7L2 TLE1 SSBP2 DOT1L BCL9	8.78e-07	116	90	7	int:TBXT
Interaction	OTUD4 interactions	RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	1.10e-06	236	90	9	int:OTUD4
Interaction	FUBP1 interactions	VPS37C SRRT CASC3 IGF2BP3 AGO2 TIAL1 MAPK1IP1L TLE1 MDC1 UPF1	1.20e-06	309	90	10	int:FUBP1
Interaction	BMI1 interactions	SRRT CASC3 IGF2BP3 AGO2 TIAL1 CASKIN2 UBAP2L PHF3 DROSHA NOL6 PRPF6 UPF1 PRPF8 PRRC2A	1.27e-06	659	90	14	int:BMI1
Interaction	ZFP36 interactions	RC3H2 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	1.50e-06	181	90	8	int:ZFP36
Interaction	YTHDF3 interactions	RC3H2 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 DOT1L PRRC2A	1.55e-06	246	90	9	int:YTHDF3
Interaction	SOX7 interactions	SOX7 ARID1B TCF7L2 SOX21 TLE1 DOT1L	1.79e-06	82	90	6	int:SOX7
Interaction	CRX interactions	TRERF1 VPS37C ARID1B TCF7L2 TLE1 RHOXF2 HGS ZMIZ1 BCL9	2.02e-06	254	90	9	int:CRX
Interaction	FAM120C interactions	RC3H2 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	2.24e-06	191	90	8	int:FAM120C
Interaction	CREBBP interactions	TRERF1 SOX7 ARID1B TCF7L2 RARA SMG7 TIAL1 CNTRL MDC1 PAX7 FOXI1 TBP PROX1	2.50e-06	599	90	13	int:CREBBP
Interaction	NUP35 interactions	USP34 ARID1B TCF7L2 POM121 SMG7 TLE1 FAM222B ZNF207 FNDC3A ZMIZ1 BCL9	2.94e-06	424	90	11	int:NUP35
Interaction	FAM168A interactions	VPS37C ARID1B TIAL1 AMOT RHOXF2 HGS KLHL42	3.41e-06	142	90	7	int:FAM168A
Interaction	TLE4 interactions	IGF2BP3 SMG7 TLE1 PAX3 PAX7 FOXI1	3.51e-06	92	90	6	int:TLE4
Interaction	PDCD6 interactions	VPS37C IGF2BP3 ARID1B TCF7L2 DROSHA MAPK1IP1L FNDC3A CRKL	3.66e-06	204	90	8	int:PDCD6
Interaction	G3BP1 interactions	SRRT RC3H2 IGF2BP3 CAD AGO2 RARA SMG7 TIAL1 UBAP2L NOL6 OTUD4 UPF1 DOT1L PRPF8 PRRC2A	4.04e-06	835	90	15	int:G3BP1
Interaction	CPEB1 interactions	IGF2BP3 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	4.10e-06	146	90	7	int:CPEB1
Interaction	TNRC6A interactions	RC3H2 AGO2 SMG7 UBAP2L AMOT CNTRL MDC1 OTUD4 PRRC2A	4.48e-06	280	90	9	int:TNRC6A
Interaction	TDRD3 interactions	CASC3 RC3H2 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	4.86e-06	212	90	8	int:TDRD3
Interaction	SNRNP40 interactions	SRRT RC3H2 ARID1B RARA POM121 RNPC3 MDC1 NOL6 ZNF207 PRPF6 DOT1L BCL9 PRPF8	4.89e-06	637	90	13	int:SNRNP40
Interaction	ZC3H7A interactions	RC3H2 IGF2BP3 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	5.39e-06	215	90	8	int:ZC3H7A
Interaction	CELF1 interactions	RC3H2 IGF2BP3 AGO2 SMG7 TIAL1 UBAP2L OTUD4 UPF1 PRRC2A	5.63e-06	288	90	9	int:CELF1
Interaction	USP10 interactions	RC3H2 IGF2BP3 CAD SOX21 UBAP2L OTUD4 UPF1 DOT1L TBP	5.96e-06	290	90	9	int:USP10
Interaction	MAGED1 interactions	RC3H2 POM121 TIAL1 NUMBL MAPK1IP1L RHOXF2 HGS PRRC2A FOXI1	6.84e-06	295	90	9	int:MAGED1
Interaction	RNU12 interactions	UBAP2L RNPC3 PRPF6 PRPF8	7.01e-06	28	90	4	int:RNU12
Interaction	NCOA3 interactions	SOX7 ARID1B RARA SMG7 TIAL1 PAX7 FOXI1 TBP	7.29e-06	224	90	8	int:NCOA3
Interaction	AR interactions	TRERF1 USP34 SRRT ARID1B TCF7L2 UBAP2L PHF3 TLE1 MDC1 SSBP2 PRPF6 ZMIZ1 DOT1L BCL9 PRPF8 TBP	7.31e-06	992	90	16	int:AR
Interaction	YTHDF1 interactions	VPS37C RC3H2 AGO2 SMG7 UBAP2L OTUD4 UPF1 DOT1L PRRC2A	8.26e-06	302	90	9	int:YTHDF1
Interaction	MKRN2 interactions	SRRT RC3H2 IGF2BP3 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A PROX1	8.47e-06	385	90	10	int:MKRN2
Interaction	SP7 interactions	TRERF1 SRRT IGF2BP3 ARID1B CAD TCF7L2 TLE1 ZMIZ1 BCL9	8.70e-06	304	90	9	int:SP7
Interaction	PAIP2 interactions	CASC3 RC3H2 AGO2 SMG7 UPF1	9.10e-06	63	90	5	int:PAIP2
Interaction	RC3H1 interactions	RC3H2 IGF2BP3 CAD AGO2 SMG7 UBAP2L NOL6 E2F7 OTUD4 PRPF6 UPF1 PRPF8 PRRC2A	9.42e-06	677	90	13	int:RC3H1
Interaction	ATXN2 interactions	CASC3 RC3H2 AGO2 SMG7 UBAP2L MDC1 OTUD4 UPF1 PRRC2A	1.07e-05	312	90	9	int:ATXN2
Interaction	CEP85 interactions	RC3H2 AGO2 SMG7 UBAP2L AMOT OTUD4 PRRC2A	1.07e-05	169	90	7	int:CEP85
Interaction	POU5F1 interactions	USP34 ARID1B CAD SOX21 TIAL1 UBAP2L PHF3 MDC1 UPF1 TCF7L1 TBP BRWD1	1.09e-05	584	90	12	int:POU5F1
Interaction	LARP4B interactions	CASC3 RC3H2 IGF2BP3 AGO2 UBAP2L OTUD4 UPF1 PRRC2A	1.20e-05	240	90	8	int:LARP4B
Interaction	MECP2 interactions	PCED1B VPS37C SRRT IGF2BP3 ARID1B CAD PTPN13 NUMBL KDM5A DROSHA RNPC3 NOL6 ZNF207 SSBP2 PRPF6 UPF1 PRPF8 PROX1	1.29e-05	1287	90	18	int:MECP2
Interaction	EYA4 interactions	FOXJ2 TIAL1 AMOT MAPK1IP1L FAM222B ZMIZ1 BCL9 CRKL	1.32e-05	243	90	8	int:EYA4
Interaction	PABPC1 interactions	CASC3 RC3H2 IGF2BP3 AGO2 RARA SMG7 TIAL1 UBAP2L OTUD4 UPF1 DOT1L PRPF8 PRRC2A	1.32e-05	699	90	13	int:PABPC1
Interaction	CEP55 interactions	VPS37C COL8A1 POM121 AMOT MAPK1IP1L HGS PRPF6 LGALS4	1.92e-05	256	90	8	int:CEP55
Interaction	HELZ interactions	RC3H2 AGO2 POM121 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	1.97e-05	257	90	8	int:HELZ
Interaction	KRTAP6-2 interactions	PLSCR4 VPS37C CASC3 COL8A1 TCF7L2 RHOXF2 PAX3	2.07e-05	187	90	7	int:KRTAP6-2
Interaction	KRT82 interactions	PLSCR4 RC3H2 COL8A1 HGS	2.19e-05	37	90	4	int:KRT82
Interaction	FXR2 interactions	RC3H2 AGO2 POM121 SMG7 UBAP2L OTUD4 PRPF6 UPF1 DOT1L PRRC2A	2.20e-05	430	90	10	int:FXR2
Interaction	SIRT6 interactions	SRRT ARID1B CAD POM121 UBAP2L PHF3 AMOT MDC1 NOL6 PRPF6 UPF1 PRPF8	2.25e-05	628	90	12	int:SIRT6
Interaction	MARF1 interactions	AGO2 POM121 UBAP2L PRPF6 UPF1 CRKL	2.35e-05	128	90	6	int:MARF1
Interaction	KRTAP7-1 interactions	VPS37C TCF7L2 RHOXF2 HGS	2.44e-05	38	90	4	int:KRTAP7-1
Interaction	SECISBP2 interactions	RC3H2 SMG7 UBAP2L OTUD4 PRRC2A	2.59e-05	78	90	5	int:SECISBP2
Interaction	KLF5 interactions	ARID1B TCF7L2 RARA TLE1 BCL9 PRRC2A TBP	2.70e-05	195	90	7	int:KLF5
Interaction	FUS interactions	SRRT RC3H2 IGF2BP3 TCF7L2 RARA UBAP2L PHF3 AMOT MDC1 PRPF6 UPF1 PRPF8 PRRC2A	3.05e-05	757	90	13	int:FUS
Interaction	RAMAC interactions	PLSCR4 VPS37C MAPK1IP1L RHOXF2 FOXI1	3.30e-05	82	90	5	int:RAMAC
Interaction	TRIM33 interactions	SOX7 ARID1B CAD UBAP2L MDC1 SSBP2 UPF1 PRPF8 FOXI1 TBP	3.43e-05	453	90	10	int:TRIM33
Interaction	SMG5 interactions	SMG7 UBAP2L OTUD4 UPF1 PRRC2A	3.71e-05	84	90	5	int:SMG5
Interaction	R3HDM1 interactions	SMG7 UBAP2L LITAF OTUD4 PRRC2A	3.71e-05	84	90	5	int:R3HDM1
Interaction	TNRC6B interactions	RC3H2 AGO2 SMG7 UBAP2L AMOT CNTRL OTUD4 PRRC2A	3.83e-05	282	90	8	int:TNRC6B
Interaction	SMG6 interactions	RC3H2 AGO2 SMG7 UPF1 PRRC2A	3.93e-05	85	90	5	int:SMG6
Interaction	VPS37C interactions	VPS37C AGO2 TIAL1 MAPK1IP1L HGS FOXI1	4.05e-05	141	90	6	int:VPS37C
Interaction	BCL9 interactions	SMG7 SSBP2 PAX7 BCL9 FOXI1	4.16e-05	86	90	5	int:BCL9
Interaction	NFIB interactions	SOX7 ARID1B TLE1 PAX7 DOT1L BCL9	4.21e-05	142	90	6	int:NFIB
Interaction	MIR29A interactions	IGF2BP3 AGO2 TIAL1 NOL6 UPF1	4.40e-05	87	90	5	int:MIR29A
Interaction	TLE1 interactions	PLSCR4 SOX7 SMG7 TLE1 PAX7 FOXA3 FOXI1	4.75e-05	213	90	7	int:TLE1
Interaction	MAPK1IP1L interactions	VPS37C TIAL1 MAPK1IP1L HGS	4.82e-05	45	90	4	int:MAPK1IP1L
Interaction	MIR29C interactions	IGF2BP3 AGO2 TIAL1 NOL6 UPF1	4.90e-05	89	90	5	int:MIR29C
Interaction	PRR20B interactions	VPS37C TCF7L2 TIAL1 RHOXF2 FAM222B	5.18e-05	90	90	5	int:PRR20B
Interaction	PRR20C interactions	VPS37C TCF7L2 TIAL1 RHOXF2 FAM222B	5.18e-05	90	90	5	int:PRR20C
Interaction	PRR20D interactions	VPS37C TCF7L2 TIAL1 RHOXF2 FAM222B	5.18e-05	90	90	5	int:PRR20D
Interaction	RBM39 interactions	SRRT CASC3 RC3H2 IGF2BP3 CAD UBAP2L DROSHA MDC1 NOL6 PRPF6 UPF1 DOT1L PRPF8 PRRC2A HNRNPCL3	5.46e-05	1042	90	15	int:RBM39
Interaction	NANOG interactions	TRERF1 USP34 ARID1B SOX21 TIAL1 RHOXF2 NOL6 ZMIZ1 DOT1L TCF7L1	5.67e-05	481	90	10	int:NANOG
Interaction	CNOT6L interactions	RC3H2 AGO2 SMG7 UBAP2L PRRC2A	6.06e-05	93	90	5	int:CNOT6L
Interaction	UFSP1 interactions	VPS37C TCF7L2 FAM222B FOXI1	6.76e-05	49	90	4	int:UFSP1
Interaction	ZNF34 interactions	PLSCR4 VPS37C TCF7L2 HGS	6.76e-05	49	90	4	int:ZNF34
Interaction	YTHDF2 interactions	CASC3 RC3H2 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	7.78e-05	312	90	8	int:YTHDF2
Interaction	CNOT9 interactions	RC3H2 AGO2 SMG7 UBAP2L OTUD4 UPF1 PRRC2A	7.91e-05	231	90	7	int:CNOT9
Interaction	MCRIP2 interactions	CASC3 RC3H2 UBAP2L PRRC2A	7.92e-05	51	90	4	int:MCRIP2
GeneFamily	Phospholipid scramblases	PLSCR4 PLSCR3	1.15e-04	5	62	2	954
GeneFamily	PRD class homeoboxes and pseudogenes	RHOXF2B RHOXF2 PAX3 PAX7	2.79e-04	92	62	4	521
GeneFamily	Paired boxes	PAX3 PAX7	4.10e-04	9	62	2	675
GeneFamily	Forkhead boxes	FOXJ2 FOXA3 FOXI1	4.30e-04	43	62	3	508
GeneFamily	AT-rich interaction domain containing	ARID1B KDM5A	1.18e-03	15	62	2	418
GeneFamily	SRY-boxes	SOX7 SOX21	1.91e-03	19	62	2	757
Coexpression	BENPORATH_SOX2_TARGETS	FOXJ2 IGF2BP3 ARID1B TCF7L2 AGO2 MAN2C1 SMG7 TIAL1 TLE1 MDC1 NOL6 BCL9 TCF7L1 TBP	1.53e-07	734	88	14	M3835
Coexpression	DAZARD_UV_RESPONSE_CLUSTER_G6	IGF2BP3 AGO2 PHF3 OTUD4 FNDC3A SSBP2 ZMIZ1	5.99e-07	145	88	7	M1810
Coexpression	DAZARD_RESPONSE_TO_UV_NHEK_DN	IGF2BP3 AGO2 KDM5A PHF3 MDC1 OTUD4 FNDC3A SSBP2 ZMIZ1	7.74e-07	300	88	9	M8702
Coexpression	GSE37533_PPARG1_FOXP3_VS_PPARG2_FOXP3_TRANSDUCED_CD4_TCELL_UP	FOXJ2 PTPN13 AGO2 NOL6 SSBP2 ZDHHC3 TBP	2.36e-06	178	88	7	M8996
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	USP34 COL8A1 IGF2BP3 TCF7L2 PTPN13 AGO2 KDM5A PHF3 TLE1 OTUD4 FNDC3A SSBP2 ZMIZ1	5.49e-06	856	88	13	M4500
Coexpression	DIRMEIER_LMP1_RESPONSE_LATE_UP	SRRT POM121 LITAF OTUD4	3.81e-05	56	88	4	M4976
Coexpression	GSE45837_WT_VS_GFI1_KO_PDC_UP	FOXJ2 ARPP21 AGO2 RARA FAM222B HGS	5.13e-05	195	88	6	M9892
Coexpression	GSE23502_BM_VS_COLON_TUMOR_MYELOID_DERIVED_SUPPRESSOR_CELL_DN	ARID1B TIAL1 MDC1 KLHL42 ZNF207 BRWD1	5.90e-05	200	88	6	M8088
Coexpression	GSE43955_10H_VS_60H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP	VPS37C MAN2C1 LITAF PRPF6 PRPF8 TBP	5.90e-05	200	88	6	M9686
Coexpression	GSE18281_PERIMEDULLARY_CORTICAL_REGION_VS_WHOLE_CORTEX_THYMUS_UP	RC3H2 UBAP2L FAM222B UPF1 BCL9 TCF7L1	5.90e-05	200	88	6	M7256
Coexpression	GSE17721_0.5H_VS_4H_PAM3CSK4_BMDC_DN	PHF3 OTUD4 ZNF207 TMEM143 BCL9 BRWD1	5.90e-05	200	88	6	M4108
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	POM121 SMG7 TIAL1 NUMBL FNDC3A DOT1L	6.95e-05	206	88	6	M2817
Coexpression	STARK_PREFRONTAL_CORTEX_22Q11_DELETION_UP	POM121 SMG7 TIAL1 NUMBL FNDC3A DOT1L	7.33e-05	208	88	6	MM581
Coexpression	SENESE_HDAC1_TARGETS_UP	USP34 SRRT IGF2BP3 AGO2 SMG7 OTUD4 PRPF6 COL22A1	1.39e-04	451	88	8	M14973
Coexpression	ZHOU_INFLAMMATORY_RESPONSE_LIVE_UP	SHANK1 TCF7L2 AGO2 LITAF PAX3 ACVR2A DOT1L CLCF1	1.42e-04	452	88	8	M18685
Drug	Cefoxitin sodium salt [33564-30-6]; Down 200; 8.8uM; HL60; HT_HG-U133A	RC3H2 TCF7L2 RARA KDM5A PHF3 SSBP2 PLSCR3 CRKL LGALS4	6.29e-08	194	88	9	2735_DN
Drug	Bacampicillin hydrochloride [37661-08-8]; Up 200; 8uM; MCF7; HT_HG-U133A	FOXJ2 COL8A1 RARA OTUD4 UPF1 PLSCR3 BCL9 PRRC2A LGALS4	7.82e-08	199	88	9	3273_UP
Drug	indomethacin, USP; Up 200; 20uM; MCF7; HG-U133A	TCF7L2 SOX21 TIAL1 CASKIN2 FNDC3A PAX3 TMEM143	1.00e-05	193	88	7	262_UP
Drug	Flumethasone [2135-17-3]; Down 200; 9.8uM; PC3; HT_HG-U133A	USP34 TCF7L2 SMG7 PHF3 OTUD4 PRPF6 UPF1	1.04e-05	194	88	7	4272_DN
Drug	Guaifenesin [93-14-1]; Down 200; 20.2uM; MCF7; HT_HG-U133A	USP34 MAN2C1 CASKIN2 TLE1 YIPF4 UPF1 PLSCR3	1.04e-05	194	88	7	3431_DN
Drug	Carbinoxamine maleate salt [3505-38-2]; Down 200; 9.8uM; PC3; HT_HG-U133A	FOXJ2 TCF7L2 KDM5A UBAP2L YIPF4 SSBP2 BRWD1	1.15e-05	197	88	7	7138_DN
Drug	Sulfisoxazole [127-69-5]; Down 200; 15uM; MCF7; HT_HG-U133A	SRRT TLE1 YIPF4 CYP26A1 OTUD4 FNDC3A CRKL	1.18e-05	198	88	7	5622_DN
Drug	Chlorhexidine [55-56-1]; Down 200; 8uM; MCF7; HT_HG-U133A	TCF7L2 RARA SMG7 CASKIN2 PHF3 CYP26A1 LGALS4	1.18e-05	198	88	7	1525_DN
Drug	nordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A	FOXJ2 RC3H2 SLC25A20 TCF7L2 PTPN13 MAN2C1 TLE1	1.22e-05	199	88	7	6942_DN
Drug	Flurbiprofen [5104-49-4]; Down 200; 16.4uM; MCF7; HT_HG-U133A	USP34 COL8A1 KDM5A PHF3 CYP26A1 FNDC3A CLCF1	1.22e-05	199	88	7	5634_DN
Drug	Tinidazole [19387-91-8]; Down 200; 16.2uM; MCF7; HT_HG-U133A	USP34 TCF7L2 RARA CASKIN2 PLSCR3 BCL9 PRRC2A	1.22e-05	199	88	7	3430_DN
Drug	1,1,3-tribromopropane	TBPL2 TBP	1.48e-05	2	88	2	CID000134838
Drug	AC1L9K70	TBPL2 RARA CYP26A1 HGS LGALS4 TBP PROX1	2.94e-05	228	88	7	CID000446871
Drug	Monobenzone [103-16-2]; Down 200; 20uM; MCF7; HT_HG-U133A	USP34 RARA SMG7 CYP26A1 OTUD4 BRWD1	8.53e-05	186	88	6	3391_DN
Drug	Imipenem [74431-23-5]; Down 200; 13.4uM; MCF7; HT_HG-U133A	USP34 CASKIN2 OTUD4 FNDC3A CLCF1 TBP	1.02e-04	192	88	6	2873_DN
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	SRRT CAD MAN2C1 UBAP2L NOL6 UPF1	1.02e-04	192	88	6	1153_DN
Drug	chlorpromazine hydrochloride; Down 200; 1uM; PC3; HT_HG-U133A	PLSCR4 TCF7L2 KDM5A PHF3 NOL6 PRRC2A	1.07e-04	194	88	6	1217_DN
Drug	Trichostatin A, from Streptomyces sp.; Down 200; 0.1uM; HL60; HT_HG-U133A	SRRT CAD NOL6 UPF1 CLCF1 PRRC2A	1.07e-04	194	88	6	2523_DN
Drug	Scopolamine hydrochloride [55-16-3]; Down 200; 11.8uM; PC3; HT_HG-U133A	PLSCR4 USP34 KDM5A FNDC3A SSBP2 BRWD1	1.07e-04	194	88	6	4219_DN
Drug	(R) -Naproxen sodium salt [26159-34-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A	RARA KDM5A FNDC3A BCL9 CRKL LGALS4	1.07e-04	194	88	6	6794_DN
Drug	Phenazopyridine hydrochloride [136-40-3]; Down 200; 16uM; MCF7; HT_HG-U133A	TCF7L2 PTPN13 RARA FAM222B PLSCR3 PRRC2A	1.11e-04	195	88	6	6234_DN
Drug	2-propylpentanoic acid; Down 200; 200uM; MCF7; HT_HG-U133A	USP34 SRRT COL8A1 KDM5A CASKIN2 CRKL	1.14e-04	196	88	6	5574_DN
Drug	Hydroquinine hydrobromide hydrate [304695-81-6]; Down 200; 9.4uM; HL60; HG-U133A	TCF7L2 SMG7 UBAP2L PHF3 FAM222B UPF1	1.14e-04	196	88	6	1775_DN
Drug	Bupropion hydrochloride [31677-93-7]; Up 200; 14.4uM; HL60; HG-U133A	KDM5A PHF3 CNTRL SSBP2 PRPF6 CLCF1	1.17e-04	197	88	6	1564_UP
Drug	Flunixin meglumine [42461-84-7]; Down 200; 8.2uM; MCF7; HT_HG-U133A	TCF7L2 RARA SMG7 CASKIN2 FAM222B PRRC2A	1.17e-04	197	88	6	3411_DN
Drug	Sulfamonomethoxine [1220-83-3]; Down 200; 14.2uM; MCF7; HT_HG-U133A	COL8A1 PTPN13 CASKIN2 CNTRL PRPF6 BRWD1	1.17e-04	197	88	6	3484_DN
Drug	Isotretinoin [4759-48-2]; Down 200; 13.4uM; MCF7; HT_HG-U133A	SRRT COL8A1 TCF7L2 CASKIN2 UBAP2L SSBP2	1.17e-04	197	88	6	6017_DN
Drug	Atracurium besylate [64228-81-5]; Up 200; 3.2uM; PC3; HT_HG-U133A	PLSCR4 SRRT RC3H2 TCF7L2 SMG7 YIPF4	1.17e-04	197	88	6	1824_UP
Drug	Diltiazem hydrochloride [33286-22-5]; Up 200; 8.8uM; MCF7; HT_HG-U133A	SRRT RARA SMG7 FAM222B FNDC3A BCL9	1.17e-04	197	88	6	5309_UP
Drug	chlorpromazine hydrochloride; Up 200; 1uM; PC3; HT_HG-U133A	RARA SOX21 PHF3 YIPF4 FNDC3A PRPF6	1.17e-04	197	88	6	1217_UP
Drug	Dimethadione [695-53-4]; Down 200; 31uM; MCF7; HT_HG-U133A	KLHL29 COL8A1 CASKIN2 CNTRL CYP26A1 PRRC2A	1.17e-04	197	88	6	5668_DN
Drug	Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A	TCF7L2 RARA CASKIN2 PHF3 UPF1 BRWD1	1.17e-04	197	88	6	2070_DN
Drug	Procaine hydrochloride [51-05-8]; Down 200; 14.6uM; PC3; HT_HG-U133A	PLSCR4 FOXJ2 VPS37C TCF7L2 PHF3 PLSCR3	1.17e-04	197	88	6	1796_DN
Drug	Sulfadimethoxine [122-11-2]; Down 200; 12.8uM; MCF7; HT_HG-U133A	SMG7 CASKIN2 PHF3 OTUD4 BCL9 PRRC2A	1.20e-04	198	88	6	3441_DN
Drug	(1)-Nipecotic acid [498-95-3]; Down 200; 31uM; MCF7; HT_HG-U133A	USP34 COL8A1 PTPN13 CYP26A1 SSBP2 CLCF1	1.20e-04	198	88	6	6500_DN
Drug	Milrinone [78415-72-2]; Down 200; 19uM; MCF7; HT_HG-U133A	TCF7L2 RARA SMG7 UBAP2L PLSCR3 BCL9	1.20e-04	198	88	6	7210_DN
Drug	Fluocinonide [356-12-7]; Down 200; 8uM; MCF7; HT_HG-U133A	SRRT TCF7L2 CYP26A1 FNDC3A CLCF1 FOXI1	1.20e-04	198	88	6	3839_DN
Drug	Phenethicillin potassium salt [132-93-4]; Down 200; 10uM; MCF7; HT_HG-U133A	USP34 TCF7L2 RARA UBAP2L FNDC3A SSBP2	1.20e-04	198	88	6	6239_DN
Drug	Tetrahydroalstonine [6474-90-4]; Down 200; 11.4uM; MCF7; HT_HG-U133A	RARA SMG7 CASKIN2 PHF3 FNDC3A UPF1	1.24e-04	199	88	6	6209_DN
Drug	Piperacetazine [3819-00-9]; Down 200; 9.8uM; HL60; HT_HG-U133A	SRRT PTPN13 KDM5A FAM222B PLSCR3 CLCF1	1.24e-04	199	88	6	6152_DN
Drug	Cyproheptadine hydrochloride [969-33-5]; Down 200; 12.4uM; PC3; HT_HG-U133A	IGF2BP3 TCF7L2 RARA KDM5A UBAP2L UPF1	1.24e-04	199	88	6	6740_DN
Drug	Oxantel pamoate [68813-55-8]; Down 200; 6.6uM; HL60; HT_HG-U133A	USP34 TCF7L2 MAN2C1 SMG7 FAM222B PRPF6	1.24e-04	199	88	6	1277_DN
Drug	Harpagoside [19210-12-9]; Up 200; 8uM; HL60; HT_HG-U133A	SHANK1 PTPN13 RARA SOX21 PLSCR3 CLCF1	1.27e-04	200	88	6	2935_UP
Disease	sitting height ratio	KLHL29 ARID1B TCF7L2 ZMIZ1	1.38e-05	51	84	4	EFO_0007118
Disease	Alveolar rhabdomyosarcoma	PAX3 PAX7	2.40e-05	3	84	2	cv:C0206655
Disease	RHABDOMYOSARCOMA 2	PAX3 PAX7	2.40e-05	3	84	2	268220
Disease	alveolar rhabdomyosarcoma (is_implicated_in)	PAX3 PAX7	2.40e-05	3	84	2	DOID:4051 (is_implicated_in)
Disease	cortical surface area measurement	KLHL29 USP34 ARID1B TCF7L2 YIPF4 MDC1 SSBP2 PAX3 COL22A1 PAX7 ACVR2A PRRC2A TCF7L1 CRKL	2.49e-05	1345	84	14	EFO_0010736
Disease	lung carcinoma (is_marker_for)	MDC1 CRKL	7.96e-05	5	84	2	DOID:3905 (is_marker_for)
Disease	Alveolar rhabdomyosarcoma	PAX3 PAX7	7.96e-05	5	84	2	C0206655
Disease	prostate cancer (implicated_via_orthology)	PAX3 PAX7 PRPF8	1.14e-04	33	84	3	DOID:10283 (implicated_via_orthology)
Disease	Orofacial cleft, vitamin supplement exposure measurement	PAX7 GKN1	1.19e-04	6	84	2	EFO_0009116, HP_0000202
Disease	sex interaction measurement, inflammatory bowel disease	TMEM174 LITAF PRRC2A	5.25e-04	55	84	3	EFO_0003767, EFO_0008343
Disease	pulse pressure measurement	KLHL29 USP34 RC3H2 COL8A1 ARID1B TCF7L2 KDM5A CNTRL KLHL42 DOT1L TCF7L1 HYDIN	5.64e-04	1392	84	12	EFO_0005763
Disease	unipolar depression, mood disorder	KLHL29 TCF7L2 ARPP21 ACVR2A	5.92e-04	134	84	4	EFO_0003761, EFO_0004247
Disease	breast carcinoma	SHANK1 COL8A1 IGF2BP3 ARID1B TCF7L2 TIAL1 NOL6 SSBP2 ZMIZ1 DOT1L	6.31e-04	1019	84	10	EFO_0000305
Disease	erythrocyte measurement	KLHL29 USP34 FAM222B CYP26A1 NOL6	8.50e-04	257	84	5	EFO_0005047
Disease	diabetes mellitus	TCF7L2 TLE1 ZMIZ1	9.76e-04	68	84	3	EFO_0000400
Disease	psoriasis, type 2 diabetes mellitus	TCF7L2 ZMIZ1 PROX1	1.30e-03	75	84	3	EFO_0000676, MONDO_0005148
Disease	gestational diabetes	TCF7L2 NUMBL	1.95e-03	23	84	2	EFO_0004593
Disease	HMG CoA reductase inhibitor use measurement	TCF7L2 LITAF FAM222B CYP26A1	2.11e-03	189	84	4	EFO_0009932
Disease	stomach carcinoma (is_marker_for)	KDM5A MDC1	2.12e-03	24	84	2	DOID:5517 (is_marker_for)
Disease	fasting blood glucose measurement, HOMA-B, fasting blood insulin measurement	TCF7L2 PROX1	2.30e-03	25	84	2	EFO_0004465, EFO_0004466, EFO_0004469
Disease	Deafness	PAX3 FOXI1	2.30e-03	25	84	2	C0011053
Disease	brain cancer (implicated_via_orthology)	NUMBL PROX1	2.49e-03	26	84	2	DOID:1319 (implicated_via_orthology)
Disease	17-hydroxyprogesterone measurement	MDC1 PRRC2A	3.09e-03	29	84	2	EFO_0010220
Disease	sodium measurement	UBQLNL TCF7L2 ARPP21	3.21e-03	103	84	3	EFO_0009282
Disease	obesity (implicated_via_orthology)	TCF7L2 PLSCR3 TCF7L1 PROX1	3.36e-03	215	84	4	DOID:9970 (implicated_via_orthology)
Disease	chronic obstructive pulmonary disease	COL8A1 TCF7L2 TLE1 OTUD4 DOT1L BCL9 TCF7L1	3.49e-03	688	84	7	EFO_0000341

Protein segments in the cluster

Peptide	Gene	Start	Entry
RGPPPEYPFKGMPPQ	AMOT	236	Q4VCS5
PPFVPPPGYMMYTVL	CNTRL	1236	Q7Z7A1
MAYPPVLVPTQDPGP	ACVR2A	166	P27037
MGIQPPKGVLLYGPP	SPATA5	656	Q8NB90
PGGPTQAPPYPGMNR	ARID1B	1551	Q8NFD5
GPFPPGPQFALGPMS	DOT1L	1466	Q8TEK3
EPPSGPVYPSSLMPQ	ARPP21	571	Q9UBL0
MYSGAGPALAPPAPP	AGO2	1	Q9UKV8
VPAYPGLGYPPMPRV	NUMBL	491	Q9Y6R0
GPVPPVPSGMYAPVY	RC3H2	681	Q9HBD1
MFPQPSFGPNPFLGP	OTUD4	836	Q01804
FFFPPMLGGLSPPGA	RARA	26	P10276
GFPPTGMPTLPPYQL	PAX7	291	P23759
TMEGPPTFNPPVPYF	LGALS4	181	P56470
SYYPTPPAPMPGPTT	LITAF	31	Q99732
IYVTPGVQPPPPQMG	MDC1	2001	Q14676
GGMYSFPARVPPPPP	HNRNPCL3	121	B7ZW38
GRPFPPINVPGMVLY	FSIP2	986	Q5CZC0
MAGYLPPKGYAPSPP	PLSCR3	1	Q9NRY6
PGPTPMANCPPGLEY	PLSCR4	101	Q9NRQ2
GPQLPMPFFPTPRYQ	PCED1B	376	Q96HM7
PSPPVNGMAAPLAYP	FAM222B	431	Q8WU58
PGPSSLMPVLGYDPP	NOL6	1041	Q9H6R4
QPPSLPGQPPMYSGT	SLC25A20	41	O43772
GGMYSFPARVPPPPP	HNRNPCL4	121	P0DMR1
PGPSPMYPIPTQDSA	FOXJ2	526	Q9P0K8
PAPRYPSPPMGSVSA	CRKL	101	P46109
FMYPQGSPSSPAPGP	CASKIN2	756	Q8WXE0
SPGPAPPPSFIMSYK	KDM5A	1666	P29375
TSGPPSAMTPPYPQF	IGF2BP3	386	O00425
PGGFPPTAMPTLPTY	PAX3	291	P23760
LMGSYLGKPGPPQPA	POM121	136	Q96HA1
FNLVMPPMPPPGYFG	UPF1	996	Q92900
RPPLESQYGYPGMPP	ERVK-19	221	Q9YNA8
PGMPPALQGRAPYPQ	ERVK-5	231	Q9HDB9
PGGPPPKGLMYSVNP	GKN1	111	Q9NS71
PLFGMALPPKPQGPF	HYDIN	5016	Q4G0P3
NPGLYPPPVSMSPGQ	CASC3	596	O15234
MVLPSPPLGPFPVLY	E2F7	746	Q96AV8
MSPNGSVPPIYVPPG	FNDC3A	66	Q9Y2H6
VRGPPPPYQMTPSEG	BCL9	511	O00512
PTPPPQGEYLPDMGL	COL8A1	576	P27658
YMKSSQGRPGPPGPP	COL22A1	1491	Q8NFW1
PPEMPVNYGSPPNLV	BRWD1	136	Q9NSI6
LVTVPSMGYAPVPPP	MAN2C1	651	Q9NTJ4
SMGYAPVPPPTSLQP	MAN2C1	656	Q9NTJ4
ALPLPPGTMGFPFFG	CYP26A1	41	O43174
NGPTMTPPPYLPGPN	FOXI1	66	Q12951
SPLPPDMAPGQSYQP	PTPN13	1726	Q12923
PAPTGMYPSVPPTGP	MAPK1IP1L	66	Q8NDC0
GPTGPYPTPNMPFPE	MAPK1IP1L	111	Q8NDC0
IPNPYPPSSFMAPGF	MS4A12	16	Q9NXJ0
QGLLPPFPPGMFPLW	SYVN1	371	Q86TM6
FPPMPVPPAGFAGLT	SYVN1	471	Q86TM6
PVPGAPPGQGTFPFM	DROSHA	131	Q9NRR4
TYPYGLPTPPEMSPL	SOX7	196	Q9BT81
GPVPPGFFQPFMSPR	SSBP2	116	P81877
PGLQPPLAYILLPGM	SOX21	246	Q9Y651
LPEGPVPQSPPASMY	PSD	26	A5PKW4
KPFLGMPAPLGYVPG	PRPF6	6	O94906
MTLNPLSSPYPPGGL	FOXA3	41	P55318
LPLMAYPFQSPLGAP	PROX1	486	Q92786
PPTYVIPPPVAFSMG	SMG7	666	Q92540
QPSGPPQFPPYRGMM	PRRC2A	236	P48634
LPPMPPAGQAEFGPF	RHOXF2B	261	P0C7M4
PEPFSMPSLLGAPPY	RNF217	231	Q8TC41
PAYQGPGIPELLSPM	OS9	91	Q13438
SYERPSFLPPGPGLM	SHANK1	871	Q9Y566
STPGPPYPPQLMTPS	SHANK1	1741	Q9Y566
TPQGLMPYGQPRPPI	SRRT	791	Q9BXP5
MAALGYPLPQPLPGT	CLCF1	151	Q9UBD9
GNPVPGPLAPLPDYM	PRPF8	11	Q6P2Q9
PLAVPGPYPAPFGMV	TLE1	361	Q04724
PPPYPGPVGTMWFIR	ZDHHC3	26	Q9NYG2
PPLLPNPYIMAPGLL	UBAP2L	796	Q14157
PTPFGPITARPPMYE	RNPC3	196	Q96LT9
LQALTPSMGLYPPPG	TMEM143	421	Q96AN5
PSMGLYPPPGFPKLD	TMEM143	426	Q96AN5
GPPYPGYPFLMIPDL	TCF7L1	116	Q9HCS4
PLPGTTPLYPSPMTP	TBP	131	P20226
KGPPYPGYPFIMIPD	TCF7L2	96	Q9NQB0
QPAPAAGPYPSMPST	HGS	611	O14964
PFPGPPNFPPQSMFG	PHF3	1816	Q92576
LPPMPPAGQAEFGPF	RHOXF2	261	Q9BQY4
PLNPQPYLGLETMPG	UBQLNL	251	Q8IYU4
LMGTPDGTCYPPPPV	CAD	1881	P27708
PPPYGSPEPMGINTS	TMEM174	141	Q8WUU8
QGYIPPMAQPGLPPV	ZNF207	136	O43670
MQPPGPPPAYAPTNG	YIPF4	1	Q9BSR8
GPPGMPPFASYILQR	USP34	2616	Q70CQ2
SPQRSMPPRPGYPGT	VPS37C	261	A5D8V6
PPVIPPPNQAGYGMA	TIAL1	356	Q01085
YPPPPPTVGLRSMEQ	TBPL2	21	Q6SJ96
MIAALGPGPSPYPLP	ZMIZ1	861	Q9ULJ6
PPYTPPPMLSPVRQG	TRERF1	706	Q96PN7
QLPLMPGHYSLPQPP	KLHL29	196	Q96CT2
PLAPHPYQGEPPSML	KLHL42	206	Q9P2K6