Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessnucleotide-sugar biosynthetic process

NANS PMM1 UGDH

9.18e-0623373GO:0009226
GeneOntologyBiologicalProcessnucleotide-sugar metabolic process

NANS PMM1 UGDH

6.69e-0544373GO:0009225
DomainPlexin_cytopl

PLXNA2 PLXNB1

1.52e-049392PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXNA2 PLXNB1

1.52e-049392IPR013548
DomainPlexin

PLXNA2 PLXNB1

1.52e-049392IPR031148
DomainIPT

PLXNA2 PLXNB1

1.44e-0327392SM00429
DomainTIG

PLXNA2 PLXNB1

1.90e-0331392PF01833
DomainSEMA

PLXNA2 PLXNB1

1.90e-0331392PS51004
DomainSema

PLXNA2 PLXNB1

1.90e-0331392SM00630
DomainSemap_dom

PLXNA2 PLXNB1

1.90e-0331392IPR001627
DomainSema

PLXNA2 PLXNB1

1.90e-0331392PF01403
DomainPlexin_repeat

PLXNA2 PLXNB1

2.03e-0332392IPR002165
DomainPSI

PLXNA2 PLXNB1

2.03e-0332392PF01437
DomainIPT

PLXNA2 PLXNB1

2.03e-0332392IPR002909
DomainPDZ

MPDZ CNKSR3 PDZRN4

3.16e-03141393PF00595
DomainPDZ

MPDZ CNKSR3 PDZRN4

3.62e-03148393SM00228
Domain-

MPDZ CNKSR3 PDZRN4

3.75e-031503932.30.42.10
DomainPSI

PLXNA2 PLXNB1

3.80e-0344392IPR016201
DomainPDZ

MPDZ CNKSR3 PDZRN4

3.83e-03151393PS50106
DomainPDZ

MPDZ CNKSR3 PDZRN4

3.90e-03152393IPR001478
DomainPSI

PLXNA2 PLXNB1

4.15e-0346392SM00423
DomainTPR_8

DNAJC3 TONSL

5.47e-0353392PF13181
DomainFilament

IFFO2 KRT28

9.64e-0371392SM01391
DomainPrefoldin

CDR2 ATP6V0A2

9.90e-0372392IPR009053
DomainFilament

IFFO2 KRT28

1.02e-0273392PF00038
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

SPC24 IFFO2 CCT8 PPP1R7 CCDC88C HAUS8 FAM184A ODF2L NANS EPB41 CNKSR3

2.19e-09853401128718761
Pubmed

Allocation of paraventricular and supraoptic neurons requires Sim1 function: a role for a Sim1 downstream gene PlexinC1.

PLXNA2 PLXNB1 ARNT2

7.81e-071640317356169
Pubmed

DAPLE and MPDZ bind to each other and cooperate to promote apical cell constriction.

CCDC88C MPDZ

1.29e-06240231268831
Pubmed

Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder.

CNNM4 PRSS3 ARNT2

1.35e-061940318711365
Pubmed

Structural basis of semaphorin-plexin signalling.

PLXNA2 PLXNB1

7.73e-06440220877282
Pubmed

A family of transmembrane proteins with homology to the MET-hepatocyte growth factor receptor.

PLXNA2 PLXNB1

7.73e-0644028570614
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

CCT8 CNNM4 MPDZ RRAS2 PTPN6 DNAJC3 DIS3 UGDH

1.28e-0597440828675297
Pubmed

An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.

IVL PPP1R7 CNNM4 HAUS8 CDR2 ACTN1 NANS DIS3 GLCCI1

1.51e-05132140927173435
Pubmed

Delta proteins and MAGI proteins: an interaction of Notch ligands with intracellular scaffolding molecules and its significance for zebrafish development.

MPDZ CNKSR3

1.93e-05640215509766
Pubmed

The protein-tyrosine phosphatase SHP-1 regulates the phosphorylation of alpha-actinin.

PTPN6 ACTN1

1.93e-05640215070900
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

RNF8 CCT8 CCDC88C CNNM4 GRIN3A PDZRN4

2.01e-0549340615368895
Pubmed

The expression of plexins during mouse embryogenesis.

PLXNA2 PLXNB1

3.60e-05840215661641
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

SPC24 IFFO2 PPP1R7 HAUS8 RRAS2 ODF2L GLCCI1 TUBGCP3

4.31e-05115540820360068
Pubmed

The role of neuropilins in cell signalling.

PLXNA2 PLXNB1

4.62e-05940219909241
Pubmed

A central chaperone-like role for 14-3-3 proteins in human cells.

CCDC88C MPDZ HAUS8 CDR2 GLCCI1 EPB41 CNKSR3

5.09e-0586140736931259
Pubmed

CD95/Fas suppresses NF-κB activation through recruitment of KPC2 in a CD95L/FasL-independent mechanism.

IFFO2 TMF1 HAUS8 CDR2

8.41e-0520140434917906
Pubmed

Transmembrane semaphorin signalling controls laminar stratification in the mammalian retina.

PLXNA2 PLXNB1

8.45e-051240221270798
Pubmed

Identifications of novel host cell factors that interact with the receptor-binding domain of the SARS-CoV-2 spike protein.

MPDZ DIS3 PLXNB1 TUBGCP3 TONSL UGDH

9.31e-0565040638777146
Pubmed

A two-dimensional electrophoresis reference map of human ovary.

CCT8 UGDH

9.98e-051340216021519
Pubmed

Plexins are a large family of receptors for transmembrane, secreted, and GPI-anchored semaphorins in vertebrates.

PLXNA2 PLXNB1

9.98e-051340210520995
Pubmed

Proximity labeling of endogenous RICTOR identifies mTOR complex 2 regulation by ADP ribosylation factor ARF1.

CCT8 NANS DIS3 EPB41

1.09e-0421540435973513
Pubmed

Proteomic discovery of Max as a novel interacting partner of C/EBPalpha: a Myc/Max/Mad link.

ACTN1 GRIN3A

1.16e-041440217082780
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXNA2 PLXNB1

1.73e-041740211683995
Pubmed

Semaphorin signaling facilitates cleft formation in the developing salivary gland.

PLXNA2 PLXNB1

1.73e-041740217626059
Pubmed

AMPK, a Regulator of Metabolism and Autophagy, Is Activated by Lysosomal Damage via a Novel Galectin-Directed Ubiquitin Signal Transduction System.

CCT8 CNNM4 RRAS2 ACTN1 ATP6V0A2

2.25e-0448440531995728
Pubmed

Defining the proximal interaction networks of Arf GTPases reveals a mechanism for the regulation of PLD1 and PI4KB.

IFFO2 CCT8 TMF1 EPB41 ATP6V0A2 UGDH

2.45e-0477740635844135
Pubmed

Neither replication nor simulation supports a role for the axon guidance pathway in the genetics of Parkinson's disease.

RRAS2 PLXNA2

2.94e-042240218628988
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

CCT8 PRSS3 RRAS2 ACTN1 NANS TONSL

3.00e-0480740630575818
Pubmed

A radial axis defined by semaphorin-to-neuropilin signaling controls pancreatic islet morphogenesis.

PLXNA2 PLXNB1

3.50e-042440228893946
Pubmed

Molecular genetic linkage maps of mouse chromosomes 4 and 6.

CYP4A11 EPB41

4.12e-04264021684952
Pubmed

Expression of Robo/Slit and Semaphorin/Plexin/Neuropilin family members in the developing hypothalamic paraventricular and supraoptic nuclei.

PLXNA2 PLXNB1

4.78e-042840218617019
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

CCT8 PPP1R7 CNNM4 PTPN6 DNAJC3

4.88e-0457340528330616
Pubmed

The Tumor Suppressor CIC Directly Regulates MAPK Pathway Genes via Histone Deacetylation.

CCT8 CCDC88C ACTN1 EPB41 TONSL

5.27e-0458340529844126
Pubmed

Novel asymmetrically localizing components of human centrosomes identified by complementary proteomics methods.

HAUS8 ODF2L TUBGCP3

6.39e-0414640321399614
Pubmed

Quantifying domain-ligand affinities and specificities by high-throughput holdup assay.

MPDZ PDZRN4

7.93e-043640226053890
Pubmed

Mouse chromosomal locations of nine genes encoding homologs of human paraneoplastic neurologic disorder antigens.

CDR2 CYP4A11

7.93e-04364029344654
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

CCT8 RRAS2 ACTN1 NANS DIS3 TUBGCP3 UGDH

8.03e-04135340729467282
Pubmed

Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.

SPC24 HAUS8 ODF2L EPB41 TONSL

8.31e-0464540525281560
Pubmed

TRIM21 ameliorates hepatic glucose and lipid metabolic disorders in type 2 diabetes mellitus by ubiquitination of PEPCK1 and FASN.

IVL MMRN2 ACTN1 UGDH

9.58e-0438240437249651
Pubmed

A novel lncRNA MDHDH suppresses glioblastoma multiforme by acting as a scaffold for MDH2 and PSMA1 to regulate NAD+ metabolism and autophagy.

RRAS2 UGDH

9.79e-044040236527092
Pubmed

A proteomic snapshot of the human heat shock protein 90 interactome.

ACTN1 NANS

9.79e-044040216263121
Pubmed

The DNA sequence and analysis of human chromosome 13.

DNAJC3 DIS3 TUBGCP3

9.93e-0417040315057823
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

MMRN2 CCT8 PPP1R7 RRAS2 PTPN6 ACTN1

1.01e-03101640619056867
Pubmed

HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress.

CCT8 ACTN1

1.03e-034140224614889
Pubmed

TAPP2 links phosphoinositide 3-kinase signaling to B-cell adhesion through interaction with the cytoskeletal protein utrophin: expression of a novel cell adhesion-promoting complex in B-cell leukemia.

PTPN6 TUBGCP3

1.03e-034140219786618
GeneFamilyPlexins

PLXNA2 PLXNB1

7.68e-059272683
GeneFamilyPDZ domain containing

MPDZ CNKSR3 PDZRN4

1.47e-031522731220
ToppCellControl-Lymphoid_T/NK-Treg|Control / Disease group, lineage and cell class

CDR2 FAM184A ODF2L GLCCI1 EPB41

8.03e-07193405715f2bbee12a7952cba85d9cd8820411983ce790
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDR2 FAM184A ODF2L GLCCI1 EPB41

8.24e-07194405fd3d5ac94de3db7136684c86f8589631ad87e6d8
ToppCellPBMC-Control-Lymphocyte-T/NK-CD4+_T-Treg|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

CDR2 FAM184A ODF2L GLCCI1 EPB41

8.24e-071944052faf49d85d09932c9c20d9f675c8093ad802fae5
ToppCellControl-Control-Lymphocyte-T/NK-Treg|Control / Disease, condition lineage and cell class

CDR2 FAM184A ODF2L GLCCI1 EPB41

9.34e-071994056b7eb14bf03aa05f2d4ac4f5dd1ccf41a7e47bd1
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D122|Adult / Lineage, Cell type, age group and donor

FAM184A GLCCI1 ARNT2 PMM1

1.18e-0515740431d1bd9138c60e8485664ec4144f987226e3eef9
ToppCell(1)_Control_(PBS)-(4)_COL2.3+_osteoblasts|(1)_Control_(PBS) / Stress and Cell class

SPC24 CDR2 NANS UGDH

1.27e-051604048450466fc2465c56798df2b520edd23c2c2e941c
ToppCellHealthy_donor-Treg|World / disease group, cell group and cell class (v2)

CDR2 FAM184A ODF2L EPB41

1.77e-05174404dc3b06420b0ad9c7060571e7bf5714e028d598bf
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IVL CNNM4 PLXNB1 TONSL

2.07e-05181404c68d272eb41f81bd8ea4d0360733a2396bc87037
ToppCellfacs-Heart-RA-24m-Myeloid-macrophage|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IVL CNNM4 PLXNB1 TONSL

2.07e-051814045e5eb89f224ee48065a328ade030cbc4dcdcac12
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C PTPN6 CNKSR3 PDZRN4

2.45e-0518940438acb307907fde68b992057714448c1561d69ee3
ToppCellHealthy-Treg|Healthy / disease group, cell group and cell class

CDR2 FAM184A GLCCI1 EPB41

2.60e-051924049d3795a64bf0c62f460d80730c5615869fc46933
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAM184A ODF2L GLCCI1 EPB41

2.60e-05192404d85a785a12076e34c404171363a647f318926b18
ToppCellBAL-Severe-Lymphocyte-T/NK-CD4+_T-Treg|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

FAM184A ODF2L GLCCI1 EPB41

2.60e-05192404230f3090607a62bb6d1e1f4b0341ee96d93f1c00
ToppCellCOVID-19-Lymphoid-Tregs|COVID-19 / Condition, Lineage and Cell class

FAM184A ODF2L GLCCI1 EPB41

2.77e-05195404284cfff4d59ecc1430997b118de17fee167dcbb1
ToppCell(2)_5-FU|World / Stress and Cell class

MPDZ RRAS2 ACTN1 PLXNA2

2.77e-05195404e5b1d96fafeb2f3b1f4cdf6b2c9eddef36bca7ff
ToppCellT_cells-Treg_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

CDR2 FAM184A GLCCI1 EPB41

2.88e-05197404de5448fcdf4e433fc167496413abe5d0c8a5c6d8
ToppCellcontrol-Treg|control / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CDR2 ODF2L GLCCI1 EPB41

2.88e-05197404a80674a0b996aa57d52bfff7264c57caf4c31cc6
ToppCellT_cells-Treg_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

CDR2 FAM184A ACTN1 EPB41

2.88e-05197404ec9398ae3577f61d6b1e6aba50ef4261aaaa7610
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-Neuronal-PNs|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.

TMF1 DNAJC3 NANS PLXNA2

2.94e-051984046408653e956fedb284fa5e69ba8f4d620731f556
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)-|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MMRN2 ACTN1 NANS CNKSR3

3.00e-0519940462936fb64b33f7ad671f9c610bed665f17d3145e
ToppCell367C-Endothelial_cells-Endothelial-A_(Artery)|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)

MMRN2 ACTN1 NANS CNKSR3

3.00e-05199404f53e0e4c34e6aec81ab07593aa11e045ba04df06
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-Treg|COVID-19_Mild / Disease, condition lineage and cell class

CDR2 ODF2L GLCCI1 EPB41

3.05e-05200404c6ae15f7deba26008af5b647855675003bb2ebcd
ToppCellmild-gd_T|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CCDC88C RRAS2 ODF2L EPB41

3.05e-05200404109f673a4967ffa52270a0b4f818b3461288db44
ToppCellFrontal_cortex-Macroglia-POLYDENDROCYTE-P1-P1_1-Tnr-Polydendrocyte.Tnr.Opalin_(Opalin)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

RRAS2 KRT28 CNKSR3

7.25e-0590403eb88d37432f93949186df6fa9000423304914ea1
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c03-ITGA4|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMF1 CNNM4 GRIN3A

2.41e-041354030e5dfbe79598fc7822a7b3baa8d7dba3c9da1dad
ToppCelldroplet-Fat-SCAT-30m-Myeloid-monocyte|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 FAM184A TONSL

3.47e-041534032731c3d4ac40ecc22108f8f3f45a069077159125
ToppCell10x5'-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

MPDZ FAM184A PLXNB1

3.68e-0415640310d191e29b16cae8238e8df6c0ff38882253f34e
ToppCellE15.5-Hematopoietic|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CDR2 PTPN6 EPB41

3.75e-041574036315aef4b9bf673069d43a730d4e940011509ac1
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c12-FOXP3|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PPP1R7 CCDC88C FAM184A

4.18e-04163403453e0bb292baca2938d24582fedfd6a8bb1e78e9
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Adult / Lineage, Cell type, age group and donor

FAM184A GLCCI1 ARNT2

4.18e-04163403e819a1d6d28290854aa0672b3a18fa9e293d8f23
ToppCellfacs-Large_Intestine-Proximal-24m-Epithelial-enterocyte_of_epithelium_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CNNM4 PMM1 UGDH

4.25e-041644032a00515d91ea03efcfc2a3d3c805dc2711867fcd
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

RRAS2 PTPN6 NANS

4.56e-0416840308eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

RNF8 IVL SPC24

4.56e-0416840308f6e171a1ea5cf65149744296d0fcd6c7b9684e
ToppCellCOVID-19_Moderate-Treg|World / disease group, cell group and cell class

CDR2 ODF2L EPB41

4.64e-0416940327ad11239559b025bef582f89b2a83501d9d3993
ToppCellfacs|World / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMF1 CCDC88C CNNM4

4.81e-04171403c9990bc041a632b2f7bbebbfe737772c423d7027
ToppCell10x3'2.3-week_12-13-Myeloid_neutrophil-granulo-eo/baso/mast-eosinophil|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

PRSS3 PTPN6 ATP6V0A2

4.97e-041734031e4afa020fae682521335b440ccd33c16f37156f
ToppCellfacs-Marrow-T_cells-18m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDR2 DNAJC3 NANS

4.97e-04173403e0cf99ddbe6e9eab05d7bf89e9aa124850c6a807
ToppCellHealthy_donor-Treg|Healthy_donor / disease group, cell group and cell class (v2)

CDR2 FAM184A EPB41

5.06e-041744031d76921c8404b5be5fbe9f3157d53578033f2ad2
ToppCellfacs|World / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMF1 CCDC88C CNNM4

5.14e-0417540353e96956019f984decc1c81376ebc88fbf3c4d40
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D122|Adult / Lineage, Cell type, age group and donor

FAM184A GLCCI1 ARNT2

5.23e-041764033fee8a367bb9755aca1b7fcc968b08e51b6e9436
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

FAM184A AUH GLCCI1

5.23e-04176403856a8c4211ea33d926b18d8959a03909562aa563
ToppCellCOPD-Lymphoid-T_Regulatory|World / Disease state, Lineage and Cell class

CCDC88C FAM184A GLCCI1

5.58e-0418040351a12fbad5fa7bb12e6d616a02ff9b5141e2b063
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRAS2 ATP6V0A2 CNKSR3

5.67e-041814034e81ec1580e9acb22c32c465eb46f83d1e9e424e
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRAS2 ATP6V0A2 CNKSR3

5.67e-04181403ad30c01290fb98adbd0caed301a584761212c977
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RRAS2 ATP6V0A2 CNKSR3

5.67e-041814033a3268a4dff8ffcb79e09f46490e138c96f8d916
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRSS3 PLXNA2 PDZRN4

5.76e-04182403205d9ad1ea4b7adee8054496cdde46c9c401a19a
ToppCellCF-Lymphoid-T_cell_&_NK_cell|CF / Disease state, Lineage and Cell class

CCDC88C ODF2L GLCCI1

5.76e-04182403a8dfc59a3974e3433f434676b7c2749d0fcfc8b2
ToppCelldroplet-Kidney-nan-24m-Lymphocytic-CD45____plasma_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DNAJC3 NANS GLCCI1

5.85e-04183403edb0069c66b1465dcc0bb5881417c6b17184fd74
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CCDC88C ACTN1 PLXNA2

5.85e-04183403e84539978ab4de42e19186aed00f24bb50cbc21f
ToppCellControl-T/NK_proliferative|Control / Disease group and Cell class

RNF8 SPC24 TUBGCP3

5.85e-0418340309c2b4e630f1c338f02c1242e3598e870d6b0a28
ToppCellControl-Endothelial_cells-Pulmonary_venous_endothelial_cells|Control / group, cell type (main and fine annotations)

MMRN2 CNKSR3 PDZRN4

5.85e-0418340346be9f96755c7b65aeac061d95d15abeb6466034
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRSS3 PLXNA2 PDZRN4

5.95e-04184403ca35a3d2b536c8b2bf5c4d635605e5a3ae94a428
ToppCellfacs-Thymus|facs / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 DNAJC3 GLCCI1

5.95e-0418440358beef66bbbde2479ec69dfef392d5941cedf230
ToppCellCOPD-Endothelial-VE_Venous|COPD / Disease state, Lineage and Cell class

MMRN2 CNKSR3 PDZRN4

5.95e-0418440344d716e7ba46a1ed03f5992631289653f8fd7d5e
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Adult / Lineage, Cell type, age group and donor

FAM184A GLCCI1 ARNT2

6.04e-04185403673f0c688ae6984bc8027df2da335787924f4137
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 CDR2 DIS3

6.04e-04185403efcfbf5a48b3ea9a425183e5c2eec6a9585415a0
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

MMRN2 CCDC88C GRIN3A

6.04e-04185403602536a3308a848f106adcb0a83530997440c8f4
ToppCellCOPD-Lymphoid-T_Regulatory|COPD / Disease state, Lineage and Cell class

CCDC88C FAM184A GLCCI1

6.04e-04185403846403edd4c8f646201d519055198fc38b7ffff9
ToppCelldroplet-Liver-Hepatocytes-21m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PRSS3 CDR2 DIS3

6.04e-04185403642088ace9230d38b0579853c54ff4dd8b5d5df4
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-Plasma_cells-IgM_plasma_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DNAJC3 NANS GLCCI1

6.14e-04186403a67e818c5ab682c2058fccc85f3fade0e11cb56e
ToppCell(0)_MSCs-(00)_Lepr-MSC|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MPDZ PLXNA2 PDZRN4

6.14e-04186403f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell(0)_MSCs|World / Cell class and subclass of bone marrow stroma cells in homeostatis

MPDZ PLXNA2 PDZRN4

6.14e-04186403a832c1e0035bcd559722eccf262c145deb3494c7
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Cortical_Collecting_Duct_Intercalated_Cell_Type_A|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNNM4 GLCCI1 ARNT2

6.14e-04186403a6ef5d5944af5689b5f27bef89cd05645eedbe50
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L6_THEMIS_EGR3|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PRSS3 PLXNA2 PDZRN4

6.14e-0418640377b09af860183606a1775eba921e2071e4a7dd4e
ToppCellCOVID-19-Heart-EC_2|Heart / Disease (COVID-19 only), tissue and cell type

MMRN2 CCDC88C PLXNA2

6.23e-0418740340ffc06a3e3251d9b12da390210d3e045af7537a
ToppCellCOVID-19_Mild-Neu_4|COVID-19_Mild / 5 Neutrophil clusters in COVID-19 patients

RNF8 NANS UGDH

6.23e-04187403714851e757c71c559ee6413a3f61d6c117c79ad2
ToppCell(1)_T_CD4_naive|World / Spleen cell shreds - cell class (v1) and cell subclass (v1)

FAM184A ACTN1 EPB41

6.33e-04188403b8f67ac2faadd5b848955e43ab5d6cf5e49b3681
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tregs|Lung / Manually curated celltypes from each tissue

CCDC88C FAM184A GLCCI1

6.33e-04188403604f340052807bd902915eca942a97ccc36b42e0
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

CNNM4 GLCCI1 ARNT2

6.33e-04188403e751cff2ac8fbc1487766c1871fcc5d1005286b0
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

MMRN2 CCDC88C PLXNA2

6.33e-04188403c2c51c6526defe2600302901159b8abbb58d7595
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CDR2 ODF2L EPB41

6.33e-0418840372be6fe654f3a5f654d3b9680145bce7ae9b721d
ToppCellPBMC-Mild-Lymphocyte-T/NK-CD4+_T-Treg|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CDR2 ODF2L EPB41

6.33e-041884039db3d3010cb8a1f3ee1cdccaf3cbaac3cf983fc5
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN3A UGDH PDZRN4

6.33e-04188403a244fcd092d5bd544e503366b1439b0fbc1ee00e
ToppCellCOVID-19-lung-Artery_EC|lung / Disease (COVID-19 only), tissue and cell type

MMRN2 CNKSR3 ARNT2

6.33e-04188403eecd7482b3c97d7f49993cb17edfab30c61232fc
ToppCellCOVID-19_Mild-Lymphoid_T/NK-Treg|COVID-19_Mild / Disease group, lineage and cell class

CDR2 ODF2L EPB41

6.33e-0418840342553fdc127e5f613ffd5067620a768a40f1a8a1
ToppCellCOPD-Multiplet-Multiplet|World / Disease state, Lineage and Cell class

RRAS2 GLCCI1 CNKSR3

6.33e-04188403186fe1ea328c942910190a4240262c0d8642ea3b
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN3A UGDH PDZRN4

6.33e-04188403c8530c9ff98666c64a94683261af4288cb790a7e
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C PTPN6 PDZRN4

6.43e-041894036f0fc5271a7d3682f145e734abc3be6473dda2e2
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN2 ACTN1 PLXNA2

6.43e-04189403476226787c8ea0c9834a6f4c99ac7091cc20a455
ToppCellPCW_05-06-Mesenchymal-Mesenchymal_myocytic|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

CCDC88C ACTN1 PLXNA2

6.43e-04189403b6d5dec55bf352f6ae19d8f488ae70aa10fb9a8f
ToppCellControl-Endothelial-VE_Venous|World / Disease state, Lineage and Cell class

MMRN2 CNKSR3 PDZRN4

6.43e-04189403f83f7521e377ded1522639e9a35c98b3e2725bac
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN2 ACTN1 PLXNA2

6.43e-041894033fe69bad6427e41b8d2dae450828cc21e9c3b3ad
ToppCellMS-Treg-CD4_Treg|MS / Condition, Cell_class and T cell subcluster

ODF2L GRIN3A EPB41

6.43e-04189403b1310eed6113b3536868340a5b2b2587ad377fa9
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MMRN2 ACTN1 PLXNA2

6.43e-04189403d9c2adbbe3e40eb8d57200b6411533e6685ea0d2
ToppCellMS-Treg|MS / Condition, Cell_class and T cell subcluster

ODF2L GRIN3A EPB41

6.43e-041894033fa79242fb3dba4a3f52276da0124ba260423fb6
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

CDR2 ODF2L EPB41

6.43e-041894038130102c41b2978a8b83f765ce383f836a464795
ToppCellfacs-Brain_Non-Myeloid-Striatum_-18m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CCDC88C PTPN6 PDZRN4

6.43e-041894033b9ce8964b16cb2200d30cbb0bfc711dcad2380e
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-oligodendrocyte_precursor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN3A UGDH PDZRN4

6.53e-041904039b825b2586c7b173ff27fcf2abc5860faf50984a
ToppCell10x_3'_v2v3-Non-neoplastic-Endothelial-Endothelial_mature-Endo_arterial-C|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

MMRN2 PRSS3 PLXNA2

6.53e-0419040306bfb62b94b0faf467ef93d5bc5d08924c770098
ToppCellControl-Endothelial-VE_Venous|Endothelial / Disease state, Lineage and Cell class

MMRN2 ACTN1 PDZRN4

6.53e-041904034e30155203b4a8c5e496fcbe9348b67b98ebc625
ToppCellfacs-Brain_Non-Myeloid-Cortex-3m-Macroglial-Oligodendrocyte_progenitor_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GRIN3A UGDH PDZRN4

6.53e-04190403d146af1926474328a7c822bc140c4dda66e1bbfb
ToppCell10x_3'_v3-lymph_node_(10x_3'_v3)-lymphocytic-T_lymphocytic-regulatory_T_cell|lymph_node_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ACTN1 GLCCI1 EPB41

6.53e-04190403b69709323a9f1b368b5a4f87295b9f7fd9c9be8e
ToppCellControl-Endothelial-VE_Venous|Control / Disease state, Lineage and Cell class

MMRN2 CNKSR3 PDZRN4

6.63e-04191403617546cf4883dedf3323e03a53ba5adec334cf8e
ToppCellfacs-Tongue-nan-18m-Epithelial-basal_cell_of_epidermis|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPC24 PRSS3 PDZRN4

6.63e-041914032e164d5a79ffbab93985be5bd8a513fdf597c673
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FAM184A GLCCI1 PLXNA2

6.63e-04191403ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellEpithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|World / Lineage, Cell type, age group and donor

FAM184A GLCCI1 PLXNA2

6.63e-04191403d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCellControl-Plasmablast|Control / disease group and sub_cluster of B and Plasma cells(res = 0.5)

DNAJC3 NANS GLCCI1

6.63e-041914033df5bbdb29bbcbcb8476fdf126b6d4c1ac67d64b
ToppCelldroplet-Thymus-nan-18m-Lymphocytic-DN_to_DP_transition_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination__)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACTN1 DNAJC3 GLCCI1

6.63e-041914034bd9db45e7b5c0d04368e08c8199d390744aa317
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_mature_gamma-delta_T_cell-T_gdT_c14-TRDV2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

RRAS2 ODF2L GLCCI1

6.73e-0419240358a7829b411b02b422ef75e2277a868969cc23e8
ToppCellLPS-antiTNF-Endothelial-Endothelial-Vein|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MMRN2 ACTN1 CNKSR3

6.73e-0419240381baf1c4063469bb0c03a8602b40e387ba7b0dfb
DiseaseHydrocephalus

CCDC88C MPDZ

4.84e-063382cv:C0020255
DiseaseCongenital hydrocephalus

CCDC88C MPDZ

4.84e-063382cv:C0020256
Diseasehydrocephalus (is_implicated_in)

CCDC88C MPDZ

2.41e-056382DOID:10908 (is_implicated_in)
Diseasetriacylglycerol 58:10 measurement

MPDZ RRAS2

8.83e-0434382EFO_0010437
Diseasebrain connectivity measurement

CCDC88C RRAS2 PLXNA2 CNKSR3

1.71e-03400384EFO_0005210
Diseaseneuroimaging measurement

SPC24 CCDC88C RRAS2 GLCCI1 PLXNA2 CNKSR3

2.28e-031069386EFO_0004346

Protein segments in the cluster

PeptideGeneStartEntry
HQQKEEGEEAINSGQ

EPB41

16

P11171
DQLEGDHQLIQEALI

ACTN1

686

P12814
GHIQELQQDQELQRI

CYP4A11

61

Q02928
QQQLLQELQGEDHIS

GLCCI1

526

Q86VQ1
AQEHNENDQQIREGL

DNAJC3

366

Q13217
LLNVEGELEQERQQH

FAM184A

601

Q8NB25
LQQQQAELEVHQRDG

ARNT2

441

Q9HBZ2
QGEQEGVEHELQLLN

PDZRN4

656

Q6ZMN7
QEHTIRELQGQVDGN

ODF2L

496

Q9ULJ1
NELTLHQNVEADING

KRT28

181

Q7Z3Y7
VGLISHVLEQNQEGD

AUH

251

Q13825
EVQQEQQEHLLGDLQ

MMRN2

171

Q9H8L6
VEALEHESQGLQLEN

CCDC88C

661

Q9P219
RELEVQGNGQQHVEK

PLXNA2

1336

O75051
DLLDEQAQQHGISDQ

PLXNB1

1956

O43157
VLHSQLQLEDDQGVN

TUBGCP3

341

Q96CW5
GDGQQLLDALQHELV

HAUS8

256

Q9BT25
DEEGQNQLGIRIHQD

GRIN3A

1031

Q8TCU5
HQDLQQDLQLAAELG

CDR2

21

Q01850
QGEQEENLGNLIHET

IFFO2

406

Q5TF58
TEGQLQNEEIVAHDG

HSPB11

96

Q9Y547
LAEELNHGRQGENQE

FATE1

16

Q969F0
HNGIEVIEGLENNNK

PPP1R7

261

Q15435
EQHLQGLEIAQGEKD

RNF8

321

O76064
LDHQRQVTQEEGQQL

RRAS2

131

P62070
IIAEIGQNHQGDLDV

NANS

21

Q9NR45
GQLELSEQQEGQLKH

IVL

251

P07476
GQLKHLEHQEGQLEV

IVL

261

P07476
GQLEQLEEQEGQLKH

IVL

331

P07476
GQLKHLEQQEGQLEH

IVL

341

P07476
LEQQEGQLEHLEHQE

IVL

346

P07476
GQLEHLEHQEGQLGL

IVL

351

P07476
GQLEQQERQVEHLEQ

IVL

411

P07476
QVGQLKHLEEQEGQL

IVL

426

P07476
QDGQLKHLEQQEGQL

IVL

516

P07476
IQNHLGEELLQDLIN

PMM1

96

Q92871
HGDNEENKEIILQGL

DIS3

266

Q9Y2L1
NGEQLLQISHQDLEE

CNK3/IPCEF1

36

G9CGD6
NGEQLLQISHQDLEE

CNKSR3

36

Q6P9H4
HLAIVQKVNNEGEGD

CNNM4

471

Q6P4Q7
DGLHNELQTIGFQIE

UGDH

446

O60701
HEIGELQQRLQEAEN

TMF1

741

P82094
EVNGITLLGENHQDV

MPDZ

601

O75970
EQVHQGGVELQQLEA

SPC24

71

Q8NBT2
LGQGEHQQVLQAVEL

TONSL

1026

Q96HA7
QQQGVLQDRDGTIIH

PTPN6

81

P29350
GEHNIKVLEGNEQFI

PRSS3

131

P35030
SGDLQLAHQLQQEED

ZUP1

231

Q96AP4
HQEGNKNVGLDIEAE

CCT8

471

P50990
LLGSQDIEEGNHQVE

ATP6V0A2

701

Q9Y487