Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyBiologicalProcessregulation of organic acid transport

GRM7 ITGB1 PLA2R1 RAB3GAP1 ABCB11 IRS2 GABBR1

4.46e-061031327GO:0032890
GeneOntologyBiologicalProcessnegative regulation of organic acid transport

GRM7 PLA2R1 IRS2 GABBR1

5.01e-05321324GO:0032891
GeneOntologyBiologicalProcesspositive regulation of organic acid transport

ITGB1 PLA2R1 RAB3GAP1 ABCB11 GABBR1

5.19e-05631325GO:0032892
GeneOntologyBiologicalProcesscarboxylic acid transport

ACACB SLC7A6 GRM7 ITGB1 PLA2R1 RAB3GAP1 LLGL2 ABCB11 SLC16A11 IRS2 GABBR1

6.74e-0541013211GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

ACACB SLC7A6 GRM7 ITGB1 PLA2R1 RAB3GAP1 LLGL2 ABCB11 SLC16A11 IRS2 GABBR1

7.03e-0541213211GO:0015849
GeneOntologyBiologicalProcesssecretion

CPLANE2 ACACB GRM7 ITGB2 RAB44 EDNRA PLA2R1 SAA1 RAB3GAP1 LLGL2 RAB34 IGHE TBC1D1 KCNJ6 SYNGR2 SYNGR1 ABCB11 IRS2 POFUT2 GABBR1

9.77e-05122113220GO:0046903
GeneOntologyBiologicalProcessorganic anion transport

ACACB SLC7A6 GRM7 ITGB1 PLA2R1 RAB3GAP1 LLGL2 ABCB11 SLC16A11 IRS2 SLC4A4 GABBR1

1.20e-0451513212GO:0015711
GeneOntologyBiologicalProcesscellular response to water deprivation

SIPA1 AQP2

1.21e-0431322GO:0042631
GeneOntologyCellularComponentintegrin alphaX-beta2 complex

ITGAX ITGB2

4.02e-0521332GO:0034689
GeneOntologyCellularComponentexcitatory synapse

ITGB1 RAB3GAP1 KCNJ6 KCNJ9 PLXNA4

6.12e-041071335GO:0060076
GeneOntologyCellularComponentcytoplasmic vesicle membrane

NPC1 WNT6 AQP2 ITGAX ITGB1 ITGB2 RAB44 ATAD3B RAB34 CLCN5 SEC24C SYNGR2 SYNGR1 SNX18 ABCB11 TMEM163 RAB32 SNX2 SYNGR4

6.17e-04130713319GO:0030659
GeneOntologyCellularComponentvesicle membrane

NPC1 WNT6 AQP2 ITGAX ITGB1 ITGB2 RAB44 ATAD3B RAB34 CLCN5 SEC24C SYNGR2 SYNGR1 SNX18 ABCB11 TMEM163 RAB32 SNX2 SYNGR4

7.28e-04132513319GO:0012506
GeneOntologyCellularComponentneuromuscular junction

DOK7 ITGB1 SYNGR2 SYNGR1 SYNGR4

7.53e-041121335GO:0031594
DomainSynaptogyrin

SYNGR2 SYNGR1 SYNGR4

1.28e-0641293IPR016579
DomainIRS_PTB

IRS4 DOK7 IRS2

6.77e-05121293PS51064
DomainIRS

IRS4 DOK7 IRS2

1.11e-04141293PF02174
DomainIRS_PTB

IRS4 DOK7 IRS2

1.11e-04141293IPR002404
DomainPSI

ITGB1 ITGB2 PLXNA4 SEMA4A

2.38e-04441294IPR016201
DomainSAA

SAA1 SAA2

2.81e-0441292PS00992
DomainSAA

SAA1 SAA2

2.81e-0441292SM00197
DomainSAA

SAA1 SAA2

2.81e-0441292PF00277
DomainPSI

ITGB1 ITGB2 PLXNA4 SEMA4A

2.83e-04461294SM00423
DomainS1P_rcpt

S1PR2 S1PR4

4.67e-0451292IPR004061
DomainSerum_amyloid_A

SAA1 SAA2

4.67e-0451292IPR000096
DomainVWF_A

ITGAX ITGB1 ITGB2 SEC24C ITIH6

6.19e-04991295IPR002035
DomainIntegrin_dom

ITGAX ITGB1 ITGB2

6.62e-04251293IPR032695
DomainLNS2

PITPNM2 PITPNM3

6.97e-0461292IPR013209
DomainPI_transfer

PITPNM2 PITPNM3

6.97e-0461292IPR001666
DomainLNS2

PITPNM2 PITPNM3

6.97e-0461292SM00775
DomainDDHD

PITPNM2 PITPNM3

6.97e-0461292PF02862
DomainDDHD

PITPNM2 PITPNM3

6.97e-0461292PS51043
DomainDDHD_dom

PITPNM2 PITPNM3

6.97e-0461292IPR004177
DomainIntegrin_b_cyt

ITGB1 ITGB2

6.97e-0461292SM01241
DomainIntegrin_b_cyt

ITGB1 ITGB2

6.97e-0461292PF08725
DomainLNS2

PITPNM2 PITPNM3

6.97e-0461292PF08235
DomainIntegrin_bsu_cyt_dom

ITGB1 ITGB2

6.97e-0461292IPR014836
DomainLNS2/PITP

PITPNM2 PITPNM3

6.97e-0461292IPR031315
DomainRibosomal_S6_kinase_II

RPS6KA1 RPS6KA3

6.97e-0461292IPR016239
DomainDDHD

PITPNM2 PITPNM3

6.97e-0461292SM01127
DomainPH_dom-like

IRS4 FRMPD4 NUMBL DOK7 VEPH1 SSRP1 NIBAN3 TYK2 TBC1D1 IRS2

7.55e-0442612910IPR011993
DomainMARVEL

SYNGR2 SYNGR1 SYNGR4

8.34e-04271293PF01284
DomainMarvel

SYNGR2 SYNGR1 SYNGR4

9.29e-04281293IPR008253
DomainMARVEL

SYNGR2 SYNGR1 SYNGR4

9.29e-04281293PS51225
DomainIntegrin_B_tail

ITGB1 ITGB2

9.72e-0471292SM01242
DomainIntegrin_bsu_tail

ITGB1 ITGB2

9.72e-0471292IPR012896
DomainIntegrin_B_tail

ITGB1 ITGB2

9.72e-0471292PF07965
DomainINB

ITGB1 ITGB2

1.29e-0381292SM00187
DomainIntegrin_bsu_VWA

ITGB1 ITGB2

1.29e-0381292IPR002369
DomainIntegrin_beta

ITGB1 ITGB2

1.29e-0381292PF00362
DomainIntegrin_bsu

ITGB1 ITGB2

1.65e-0391292IPR015812
DomainINTEGRIN_BETA

ITGB1 ITGB2

1.65e-0391292PS00243
DomainPSI_integrin

ITGB1 ITGB2

1.65e-0391292PF17205
DomainIntegin_beta_N

ITGB1 ITGB2

1.65e-0391292IPR033760
Domain-

ITGB1 ITGB2 SEC24C ITIH6

1.72e-037412943.40.50.410
DomainPTBI

IRS4 IRS2

2.50e-03111292SM00310
DomainCation_efflux_TMD

SLC30A7 TMEM163

2.50e-03111292IPR027469
Domain-

SLC30A7 TMEM163

2.50e-031112921.20.1510.10
DomainVWFA

ITGAX ITGB1 ITGB2 ITIH6

2.51e-03821294PS50234
Pubmed

Regulated expression of p150,95 (CD11c/CD18; alpha X/beta 2) and VLA-4 (CD49d/CD29; alpha 4/beta 1) integrins during myeloid cell differentiation.

ITGAX ITGB1 ITGB2

2.23e-07413438020569
Pubmed

Specific phosphorylations transmit signals from leukocyte β2 to β1 integrins and regulate adhesion.

ITGAX ITGB1 ITGB2

2.23e-074134325278023
Pubmed

Subcellular compartment-specific molecular diversity of pre- and post-synaptic GABA-activated GIRK channels in Purkinje cells.

KCNJ6 KCNJ9 GABBR1

5.56e-075134319558451
Pubmed

Characterization of the human synaptogyrin gene family.

SYNGR2 SYNGR1 SYNGR4

5.56e-07513439760194
Pubmed

A point mutation in KINDLIN3 ablates activation of three integrin subfamilies in humans.

ITGAX ITGB1 ITGB2

1.94e-067134319234460
Pubmed

Mycobacterium tuberculosis infection of human dendritic cells decreases integrin expression, adhesion and migration to chemokines.

ITGAX ITGB1 ITGB2

9.02e-0611134323981064
Pubmed

Integrins.

ITGAX ITGB1 ITGB2

1.20e-0512134319693543
Pubmed

Polymorphisms in the SAA1/2 gene are associated with carotid intima media thickness in healthy Han Chinese subjects: the Cardiovascular Risk Survey.

SAA1 SAA2

1.47e-052134221103356
Pubmed

The rate and significance of type 1/type 2 serum amyloid A protein gene polymorphisms in patients with ankylosing spondylitis and amyloidosis.

SAA1 SAA2

1.47e-052134226300108
Pubmed

DNA sequence evidence for polymorphic forms of human serum amyloid A (SAA).

SAA1 SAA2

1.47e-05213423800865
Pubmed

Serum Amyloid A Induces Inflammation, Proliferation and Cell Death in Activated Hepatic Stellate Cells.

SAA1 SAA2

1.47e-052134226937641
Pubmed

Influence of Serum Amyloid A (SAA1) and SAA2 gene polymorphisms on renal amyloidosis, and on SAA/C-reactive protein values in patients with familial mediterranean fever in the Turkish population.

SAA1 SAA2

1.47e-052134215170927
Pubmed

Acute-phase, but not constitutive serum amyloid A (SAA) is chemotactic for cultured human aortic smooth muscle cells.

SAA1 SAA2

1.47e-052134212557751
Pubmed

Serum amyloid alpha 1-2 are not required for liver inflammation in the 4T1 murine breast cancer model.

SAA1 SAA2

1.47e-052134236817472
Pubmed

Association of genetic variation in serum amyloid-A with cardiovascular disease and interactions with IL6, IL1RN, IL1beta and TNF genes in the Cardiovascular Health Study.

SAA1 SAA2

1.47e-052134219729864
Pubmed

The sphingosine 1-phosphate receptor 2/4 antagonist JTE-013 elicits off-target effects on sphingolipid metabolism.

S1PR2 S1PR4

1.47e-052134235013382
Pubmed

No evidence for a role of adipose tissue-derived serum amyloid a in the development of insulin resistance or obesity-related inflammation in hSAA1(+/-) transgenic mice.

SAA1 SAA2

1.47e-052134223967285
Pubmed

GIRK3 deletion facilitates kappa opioid signaling in chondrocytes, delays vascularization and promotes bone lengthening in mice.

KCNJ6 KCNJ9

1.47e-052134235314385
Pubmed

Diversity and complexity of the mouse Saa1 and Saa2 genes.

SAA1 SAA2

1.47e-052134224521869
Pubmed

RSK is a principal effector of the RAS-ERK pathway for eliciting a coordinate promotile/invasive gene program and phenotype in epithelial cells.

RPS6KA1 RPS6KA3

1.47e-052134219716794
Pubmed

Heterogeneity of human serum amyloid A protein. Five different variants from one individual demonstrated by cDNA sequence analysis.

SAA1 SAA2

1.47e-05213421971508
Pubmed

The RSK family of kinases: emerging roles in cellular signalling.

RPS6KA1 RPS6KA3

1.47e-052134218813292
Pubmed

Serum amyloid A induces calcium mobilization and chemotaxis of human monocytes by activating a pertussis toxin-sensitive signaling pathway.

SAA1 SAA2

1.47e-05213427561109
Pubmed

Dissecting Integrin Expression and Function on Memory B Cells in Mice and Humans in Autoimmunity.

ITGB1 ITGB2

1.47e-052134230949178
Pubmed

Compartment-dependent colocalization of Kir3.2-containing K+ channels and GABAB receptors in hippocampal pyramidal cells.

KCNJ6 GABBR1

1.47e-052134216624949
Pubmed

Peritoneal and hematogenous metastases of ovarian cancer cells are both controlled by the p90RSK through a self-reinforcing cell autonomous mechanism.

RPS6KA1 RPS6KA3

1.47e-052134226625210
Pubmed

Human serum amyloid A. Three hepatic mRNAs and the corresponding proteins in one person.

SAA1 SAA2

1.47e-05213423183061
Pubmed

Complete primary structures of two major murine serum amyloid A proteins deduced from cDNA sequences.

SAA1 SAA2

1.47e-05213423857624
Pubmed

GPI-80, a beta2 integrin associated glycosylphosphatidylinositol-anchored protein, concentrates on pseudopodia without association with beta2 integrin during neutrophil migration.

ITGB2 VNN2

1.47e-052134214748512
Pubmed

Platelet binding to monocytes increases the adhesive properties of monocytes by up-regulating the expression and functionality of beta1 and beta2 integrins.

ITGB1 ITGB2

1.47e-052134216415171
Pubmed

beta1 and beta2 integrins activate different signalling pathways in monocytes.

ITGB1 ITGB2

1.47e-052134211931654
Pubmed

Serum amyloid A protein induces production of matrix metalloproteinases by human synovial fibroblasts.

SAA1 SAA2

1.47e-05213429605178
Pubmed

p150/95 (CD11c/CD18) expression is required for the development of experimental autoimmune encephalomyelitis.

ITGAX ITGB2

1.47e-052134217525267
Pubmed

Physical association of beta 2 integrin with GPI-80, a novel glycosylphosphatidylinositol-anchored protein with potential for regulating adhesion and migration.

ITGB2 VNN2

1.47e-052134212056825
Pubmed

Serum amyloid A is a soluble pattern recognition receptor that drives type 2 immunity.

SAA1 SAA2

1.47e-052134232572240
Pubmed

Structure of an integrin with an alphaI domain, complement receptor type 4.

ITGAX ITGB2

1.47e-052134220033057
Pubmed

Effect of serum amyloid A on selected in vitro functions of isolated human neutrophils.

SAA1 SAA2

1.47e-05213429823935
Pubmed

AA amyloidosis-resistant CE/J mice have Saa1 and Saa2 genes that encode an identical SAA isoform.

SAA1 SAA2

1.47e-052134224228751
Pubmed

The frequencies of the serum amyloid A2 alleles in healthy (Turkish, Azerbaijan and Kazakh) populations.

SAA1 SAA2

1.47e-052134216152805
Pubmed

Differential glucocorticoid enhancement of the cytokine-driven transcriptional activation of the human acute phase serum amyloid A genes, SAA1 and SAA2.

SAA1 SAA2

1.47e-052134212077270
Pubmed

S6 kinase inactivation impairs growth and translational target phosphorylation in muscle cells maintaining proper regulation of protein turnover.

RPS6KA1 RPS6KA3

1.47e-052134217494629
Pubmed

Regulation of the human acute phase serum amyloid A genes by tumour necrosis factor-alpha, interleukin-6 and glucocorticoids in hepatic and epithelial cell lines.

SAA1 SAA2

1.47e-052134214871291
Pubmed

Functional and biochemical evidence for G-protein-gated inwardly rectifying K+ (GIRK) channels composed of GIRK2 and GIRK3.

KCNJ6 KCNJ9

1.47e-052134210956667
Pubmed

Isolation and purification of two major serum amyloid A isotypes SAA1 and SAA2 from the acute phase plasma of mice.

SAA1 SAA2

1.47e-05213429518179
Pubmed

G-protein-gated potassium channels containing Kir3.2 and Kir3.3 subunits mediate the acute inhibitory effects of opioids on locus ceruleus neurons.

KCNJ6 KCNJ9

1.47e-052134212040038
Pubmed

GIRK2 splice variants and neuronal G protein-gated K+ channels: implications for channel function and behavior.

KCNJ6 KCNJ9

1.47e-052134228487514
Pubmed

Structural prerequisites for serum amyloid A fibril formation.

SAA1 SAA2

1.47e-05213428376413
Pubmed

Absence and rescue of morphine withdrawal in GIRK/Kir3 knock-out mice.

KCNJ6 KCNJ9

1.47e-052134218400906
Pubmed

Serum Amyloid A Promotes Inflammation-Associated Damage and Tumorigenesis in a Mouse Model of Colitis-Associated Cancer.

SAA1 SAA2

1.47e-052134234217896
Pubmed

Serum amyloid A, an acute phase protein, inhibits platelet activation.

SAA1 SAA2

1.47e-05213421697614
Pubmed

Serum amyloid A facilitates the binding of high-density lipoprotein from mice injected with lipopolysaccharide to vascular proteoglycans.

SAA1 SAA2

1.47e-052134221474830
Pubmed

Structure of a human serum amyloid A gene and modulation of its expression in transfected L cells.

SAA1 SAA2

1.47e-05213422890635
Pubmed

Exposure of acidic residues as a danger signal for recognition of fibrinogen and other macromolecules by integrin alphaXbeta2.

ITGAX ITGB2

1.47e-052134215665082
Pubmed

Integrin αXβ₂ is a leukocyte receptor for Candida albicans and is essential for protection against fungal infections.

ITGAX ITGB2

1.47e-052134222844116
Pubmed

The role of the specificity-determining loop of the integrin beta subunit I-like domain in autonomous expression, association with the alpha subunit, and ligand binding.

ITGB1 ITGB2

1.47e-052134211914080
Pubmed

Acute-phase serum amyloid A: an inflammatory adipokine and potential link between obesity and its metabolic complications.

SAA1 SAA2

1.47e-052134216737350
Pubmed

Murine apolipoprotein serum amyloid A in solution forms a hexamer containing a central channel.

SAA1 SAA2

1.47e-052134212456883
Pubmed

The Impairment of Macrophage-to-Feces Reverse Cholesterol Transport during Inflammation Does Not Depend on Serum Amyloid A.

SAA1 SAA2

1.47e-052134223431457
Pubmed

Large-scale isotype-specific quantification of Serum amyloid A 1/2 by multiple reaction monitoring in crude sera.

SAA1 SAA2

1.47e-052134222300576
Pubmed

Extracellular matrix-anchored serum amyloid A preferentially induces mast cell adhesion.

SAA1 SAA2

1.47e-05213429252455
Pubmed

Inflammatory remodeling of the HDL proteome impairs cholesterol efflux capacity.

SAA1 SAA2

1.47e-052134225995210
Pubmed

Linkage of protection against amyloid fibril formation in the mouse to a single, autosomal dominant gene.

SAA1 SAA2

1.47e-05213427760010
Pubmed

Serum amyloid A exhibits pH dependent antibacterial action and contributes to host defense against Staphylococcus aureus cutaneous infection.

SAA1 SAA2

1.47e-052134231819008
Pubmed

SAA does not induce cytokine production in physiological conditions.

SAA1 SAA2

1.47e-052134223165195
Pubmed

A seven-transmembrane, G protein-coupled receptor, FPRL1, mediates the chemotactic activity of serum amyloid A for human phagocytic cells.

SAA1 SAA2

1.47e-05213429892621
Pubmed

Two widely used RSK inhibitors, BI-D1870 and SL0101, alter mTORC1 signaling in a RSK-independent manner.

RPS6KA1 RPS6KA3

1.47e-052134225889895
Pubmed

Impact of serum amyloid A on high density lipoprotein composition and levels.

SAA1 SAA2

1.47e-052134220667817
Pubmed

Decreased stroma adhesion capacity of CD34+ progenitor cells from mobilized peripheral blood is not lineage- or stage-specific and is associated with low beta 1 and beta 2 integrin expression.

ITGB1 ITGB2

1.47e-052134212183834
Pubmed

Pathogenic serum amyloid A 1.1 shows a long oligomer-rich fibrillation lag phase contrary to the highly amyloidogenic non-pathogenic SAA2.2.

SAA1 SAA2

1.47e-052134223223242
Pubmed

GABAB-GIRK2-mediated signaling in Down syndrome.

KCNJ6 GABBR1

1.47e-052134220655490
Pubmed

Intestinal epithelial serum amyloid A modulates bacterial growth in vitro and pro-inflammatory responses in mouse experimental colitis.

SAA1 SAA2

1.47e-052134221067563
Pubmed

The human acute-phase serum amyloid A gene family: structure, evolution and expression in hepatoma cells.

SAA1 SAA2

1.47e-05213421656519
Pubmed

Requirement of open headpiece conformation for activation of leukocyte integrin alphaXbeta2.

ITGAX ITGB2

1.47e-052134220679211
Pubmed

A novel biologic function of serum amyloid A. Induction of T lymphocyte migration and adhesion.

SAA1 SAA2

1.47e-05213427636186
Pubmed

Neonatal mortality in an aquaporin-2 knock-in mouse model of recessive nephrogenic diabetes insipidus.

AQP2 TMEM163

1.47e-052134211035038
Pubmed

WNT6/ACC2-induced storage of triacylglycerols in macrophages is exploited by Mycobacterium tuberculosis.

ACACB WNT6

1.47e-052134234255743
Pubmed

Molecular basis for complement recognition by integrin αXβ2.

ITGAX ITGB2

1.47e-052134222393018
Pubmed

Pre- and postsynaptic regulation of locus coeruleus neurons after chronic morphine treatment: a study of GIRK-knockout mice.

KCNJ6 KCNJ9

1.47e-052134218702733
Pubmed

Phosphorylation of the skeletal muscle glycogen-targetting subunit of protein phosphatase 1 in response to adrenaline in vivo.

RPS6KA1 PPP1R3A

1.47e-052134210648825
Pubmed

Defining lipid-binding regions of human serum amyloid A using its fragment peptides.

SAA1 SAA2

1.47e-052134219665458
Pubmed

The IRS-signalling system: a network of docking proteins that mediate insulin action.

IRS4 IRS2

1.47e-05213429609109
Pubmed

Sequence and expression of chicken and mouse rsk: homologs of Xenopus laevis ribosomal S6 kinase.

RPS6KA1 RPS6KA3

1.47e-05213422779569
Pubmed

Serum amyloid A is a chemoattractant: induction of migration, adhesion, and tissue infiltration of monocytes and polymorphonuclear leukocytes.

SAA1 SAA2

1.47e-05213427516407
Pubmed

Integrin expression and integrin-mediated adhesion in vitro of human multipotent stromal cells (MSCs) to endothelial cells from various blood vessels.

ITGAX ITGB1 ITGB2

1.55e-0513134320563599
Pubmed

A trimeric Rab7 GEF controls NPC1-dependent lysosomal cholesterol export.

NPC1 ITGB1 SLC30A7 ATAD3B RAB34 SEC24C SYNGR2 SYVN1 RAB32

2.26e-05392134933144569
Pubmed

The human serum amyloid A protein (SAA) superfamily gene cluster: mapping to chromosome 11p15.1 by physical and genetic linkage analysis.

SAA1 SAA2

4.41e-05313428188252
Pubmed

SAA1 is transcriptionally activated by STAT3 and accelerates renal interstitial fibrosis by inducing endoplasmic reticulum stress.

SAA1 SAA2

4.41e-053134234597680
Pubmed

SH3P2 is a negative regulator of cell motility whose function is inhibited by ribosomal S6 kinase-mediated phosphorylation.

RPS6KA1 RPS6KA3

4.41e-053134221501342
Pubmed

Serum amyloid A3 is a high density lipoprotein-associated acute-phase protein.

SAA1 SAA2

4.41e-053134229247043
Pubmed

Structure of the murine serum amyloid A gene family. Gene conversion.

SAA1 SAA2

4.41e-05313423013853
Pubmed

Impact of individual acute phase serum amyloid A isoforms on HDL metabolism in mice.

SAA1 SAA2

4.41e-053134227018443
Pubmed

Serum amyloid A promotes cholesterol efflux mediated by scavenger receptor B-I.

SAA1 SAA2

4.41e-053134216120612
Pubmed

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection.

SAA1 SAA2

4.41e-053134225073702
Pubmed

p90 ribosomal S6 kinase and p70 ribosomal S6 kinase link phosphorylation of the eukaryotic chaperonin containing TCP-1 to growth factor, insulin, and nutrient signaling.

RPS6KA1 RPS6KA3

4.41e-053134219332537
Pubmed

The type I interferon receptor mediates tyrosine phosphorylation of insulin receptor substrate 2.

TYK2 IRS2

4.41e-05313428550573
Pubmed

p90RSK Regulates p53 Pathway by MDM2 Phosphorylation in Thyroid Tumors.

RPS6KA1 RPS6KA3

4.41e-053134236612117
Pubmed

mRNA expression and release of interleukin-8 induced by serum amyloid A in neutrophils and monocytes.

SAA1 SAA2

4.41e-053134212857601
Pubmed

Pitpnm1 is expressed in hair cells during development but is not required for hearing.

PITPNM2 PITPNM3

4.41e-053134223820044
Pubmed

Y-box binding protein-1 serine 102 is a downstream target of p90 ribosomal S6 kinase in basal-like breast cancer cells.

RPS6KA1 RPS6KA3

4.41e-053134219036157
Pubmed

Cellugyrin and synaptogyrin facilitate targeting of synaptophysin to a ubiquitous synaptic vesicle-sized compartment in PC12 cells.

SYNGR2 SYNGR1

4.41e-053134212928441
Cytoband1q23.2

OR10J3 OR10J6P KCNJ9

1.49e-043513431q23.2
GeneFamilySphingosine 1-phosphate receptors|CD molecules

S1PR2 S1PR4

2.48e-045912206
GeneFamilyPhosphatidylinositol transfer proteins

PITPNM2 PITPNM3

3.71e-0469121151
GeneFamilyCD molecules|Integrin beta subunits

ITGB1 ITGB2

8.82e-0499121159
GeneFamilyMitogen-activated protein kinase-activated protein kinases

RPS6KA1 RPS6KA3

1.34e-03119121156
GeneFamilySorting nexins|PX-BAR domain containing

SNX18 SNX2

1.60e-03129121290
GeneFamilyFibronectin type III domain containing|Sterile alpha motif domain containing|EPH receptors

EPHB4 EPHA6

2.19e-03149121095
GeneFamilyPotassium voltage-gated channel subfamily J

KCNJ6 KCNJ9

2.87e-0316912276
GeneFamilyCadherin related

CDHR2 CDH23

3.24e-031791224
GeneFamilyRAB, member RAS oncogene GTPases

RAB44 RAB34 RAB32

4.30e-0365913388
GeneFamilyOlfactory receptors, family 10

OR10J3 OR10J6P OR10X1

4.49e-0366913157
ToppCellCOVID-19-kidney-CD-IC-B|COVID-19 / Disease (COVID-19 only), tissue and cell type

FRMPD4 LGR4 TBC1D1 CYP26C1 TMEM163 DCLK2 GAREM1

1.28e-061821337ee6a8c356bbbdae55e4ea858337e079491f9f4aa
ToppCell(0)_Myeloid-(01)_Dendritic_cell-(010)_cDC|(01)_Dendritic_cell / immune cells in Peripheral Blood (logTPM normalization)

ITGAX ITGB2 RIN2 SYNGR2 SEMA4A RAB32 SNX2

2.24e-0619813374abc274edac40f8836255fac2371ffd98a32cccd
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2-cDC2_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGAX ITGB2 SLC13A4 CLYBL SYNGR2 SEMA4A

5.56e-06148133631a7c2b20970070b14d2b955020320a6f99db547
ToppCelldroplet-Lung-nan-18m-Lymphocytic-plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPLANE2 TKTL1 PKD1L3 ARMCX3 EDEM3 SYVN1

9.67e-0616313365efecdd8a069a822bc9d35b407092925a865e629
ToppCelldroplet-Lung-nan-18m-Lymphocytic-Plasma_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPLANE2 TKTL1 PKD1L3 ARMCX3 EDEM3 SYVN1

9.67e-0616313360d94a427f86e62aba12c397c6d7b8cd297f3a0e5
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Myeloid-Monocytic-Nonclassical_Monocyte-Mono_c4-CD14-CD16|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

THNSL1 CDH23 ADM RAB34 SNX18 SEC14L5

1.19e-051691336e3100eb587005e160bd0b7990fa57ec49765133d
ToppCellfacs-Spleen-nan-24m-Lymphocytic-B_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM NIBAN3 HNRNPD CIRBP ADM TMEM163

1.40e-051741336a0641908ab6feaca5cd07142d7429983a2f68668
ToppCellfacs-Lung-EPCAM-18m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RTL5 ITGAX ITGB2 RAB34 SEMA4A RAB32

1.54e-0517713367bc92314b22a876296a4e2db51e7fb0fdfd69379
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

RTL5 ITGAX ITGB2 RAB34 SEMA4A RAB32

1.65e-05179133633ed9270d257895ff3b40df2c1af878119c9f492
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Intercalated_Cell_Type_B|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

FRMPD4 LGR4 TBC1D1 KCNJ6 TMEM163 DCLK2

1.70e-051801336cfc8bfbfd3617aabbb49f9730c29b673ca157e74
ToppCellfacs-Aorta-Heart-3m-Myeloid-macrophage|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 RPS6KA1 ITGAX ITGB2 SEMA4A RAB32

1.81e-051821336df26388c0c46d1c4775103c8e802937b4d4e7470
ToppCellfacs-Lung-EPCAM-24m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 ITGAX ITGB2 SYNGR2 SEMA4A RAB32

1.86e-051831336f524501dec1dccbf44100a61395116e4525bdc89
ToppCellfacs-Aorta-Heart-3m-Myeloid-leukocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 RPS6KA1 ITGAX ITGB2 SEMA4A RAB32

1.86e-051831336062ec08d66c923f90fee771b1bf8d98bdc7e6c1b
ToppCellfacs-Lung-24m-Hematologic-myeloid|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFAIP8L2 ITGAX ITGB2 SYNGR2 SEMA4A RAB32

1.92e-051841336c451acfcd8fe28c1f4b1ea334b1129fa84a15c42
ToppCellfacs-Trachea-18m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

EPHB4 ACACB SH3GLB2 TMEM81 PLXNA4 DUOXA2

1.98e-05185133659acaf025353405948dc34ccccf37ec5c08ea903
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

VEPH1 HMGCS2 AQP2 TBC1D1 CRYBG1 SLC4A4

2.11e-0518713362d17408b3b5f09d135084fd7ccce98e6b5ca632b
ToppCelldroplet-Marrow-nan-21m-Myeloid-granulocytopoietic_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRM SSRP1 NIBAN3 CIRBP SYVN1 SNX2

2.17e-0518813362c4432cada1273d08cbdc2824922cf578e448ec8
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VEPH1 HMGCS2 AQP2 CRYBG1 SLC4A4 GAREM1

2.17e-05188133658ccb31cdf43167872ef0fc737e6f9c51ee2e060
ToppCellwk_20-22-Hematologic_Lymphocytic-B-small_pre-B-II_cell|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

NIBAN3 AEBP1 SELENOO SYVN1 SNX2 S1PR4

2.30e-051901336f49ceda3622cf079cffde9c9a9e3d0380c571d39
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

LGR4 PLPPR1 LLGL2 CLCN5 SLC4A4 GAREM1

2.52e-05193133682e8a4c40299ffcdfd5a0da711bb9de6fb8a2eaa
ToppCellVE-pDC-|VE / Condition, Cell_class and T cell subcluster

NPC1 CDH23 NIBAN3 CLCN5 AEBP1 PLXNA4

2.52e-051931336583724de588fcde3aeda056138c522dc0225a387
ToppCellVE-pDC|VE / Condition, Cell_class and T cell subcluster

NPC1 CDH23 NIBAN3 CLCN5 AEBP1 PLXNA4

2.52e-051931336bb759dc9ef0ec41d655002f59021d62d62d44289
ToppCellwk_20-22-Hematologic-Myeloid-DC2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TNFAIP8L2 ITGAX ITGB2 SYNGR2 SEMA4A RAB32

2.59e-0519413366a9bb5ad04aba13a4886fa27a96e28e90b6586e3
ToppCell3'-Child04-06-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S1PR2 OAZ1 VNN2 SYNGR2 SEMA4A SYVN1

2.67e-051951336cccc9c70bb8f6df8c6ab94534c17475af1d3e224
ToppCellMild/Remission-B_naive-8|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

SIPA1 NIBAN3 CIRBP AEBP1 TBC1D1 IRS2

2.67e-0519513360a3221e4d1fa31a35868bdda0f0cc873c233b407
ToppCell(010)_cDC|World / immune cells in Peripheral Blood (logTPM normalization)

MAT2A ITGAX RAB34 SYNGR2 SEMA4A RAB32

2.67e-0519513364aabb3f5ce70100e4d98d7fa9f8d12e84fb9fe3d
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRF6 SYNGR1 SLC16A11 DCAF11 SLC4A4 DUOXA2

2.67e-0519513364d7ca21f14730e1b6d0473bc1a11aa626db948f3
ToppCellIIF-Myeloid-cDC|IIF / Disease, Lineage and Cell Type

MAT2A ITGAX RAB34 SYNGR2 SEMA4A RAB32

2.67e-05195133681225852a5827e973cb3b1da5c41e93d5407ecb6
ToppCelldroplet-Trachea-3m-Epithelial-airway_epithelial-epithelial_cell-epithelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

IRF6 SYNGR1 SLC16A11 DCAF11 SLC4A4 DUOXA2

2.67e-0519513368727554ef047ca7f1d4b888a8468f148c64a6918
ToppCelldroplet-Trachea-nan-3m-Epithelial-epithelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IRF6 SYNGR1 SLC16A11 DCAF11 SLC4A4 DUOXA2

2.67e-0519513369f0ee826d4f0997aee8d63284ed24549bbdf6a28
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

TNFAIP8L2 MAT2A ITGAX RAB34 SEMA4A RAB32

2.74e-0519613360bac14c018487ca67e7f9255b5f186e7ae665774
ToppCellPBMC-Mild-Myeloid-cDC-cDC-cDC_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TNFAIP8L2 MAT2A ITGAX RAB34 SEMA4A RAB32

2.74e-05196133633345338c825484960daa1ed82a19df38ccfc5c0
ToppCellmLN-B_cell-B_cell_cycling|mLN / Region, Cell class and subclass

LGR4 S1PR2 ADM NLN IGHE SYVN1

2.82e-051971336806dddcca85c82bd642008d930c8db16b613d88e
ToppCellproximal-Epithelial-Ionocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRS4 PLPPR1 TBC1D1 KCNJ6 CYP26C1 MMP11

2.82e-051971336f65c35761da7c168d5c6e4d7edf5dafa26652fe4
ToppCellproximal-Epithelial-Ionocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRS4 PLPPR1 TBC1D1 KCNJ6 CYP26C1 MMP11

2.82e-051971336e5d5accefaacea5ed2e22f906f5bcbc75083f287
ToppCellCOVID-19_Mild-Myeloid-cDC|COVID-19_Mild / Disease group, lineage and cell class

TNFAIP8L2 MAT2A ITGAX RAB34 SEMA4A RAB32

2.82e-0519713362901904b8a791fac2668fd737eff7e7144378db4
ToppCellproximal-3-Epithelial-Ionocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

IRS4 PLPPR1 TBC1D1 KCNJ6 CYP26C1 MMP11

2.82e-051971336288492fc67d8e81349d38e82caf1f1890276b299
ToppCellmLN-(2)_B_cell-(24)_B_cell_cycling|mLN / shred on region, Cell_type, and subtype

LGR4 S1PR2 ADM NLN IGHE SYVN1

2.82e-05197133670fff2d6723f259e18e7a21d22dc46d71f0759ce
ToppCell(2)_NK/T-(20)_NK_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

TKTL1 ITGAX ITGB2 LLGL2 RIN2 SYNGR1

2.90e-0519813362e4851e49457940e841660c5d781499ffb4a2bf1
ToppCell3'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_1_(CCL11+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S1PR2 ABCA8 CIRBP ADM RAB34 AEBP1

2.90e-05198133638b37daf41d84e5bf913eb3f72963418b7c0aac6
ToppCell(2)_NK/T-(200)_CD56+_NK_cell|(2)_NK/T / immune cells in Peripheral Blood (logTPM normalization)

TKTL1 ITGAX ITGB2 LLGL2 RIN2 SYNGR1

2.90e-05198133603477a6356a3c08c6e723165c0aac3464ef01667
ToppCellBronchial-10x5prime-Stromal-Peri/Epineurial_-NAF_epineurial|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

UBR1 NUMBL WNT6 SIPA1 PITPNM3 DCLK2

2.99e-051991336a13f4b8a039304e685464cc8879659824cad5a3e
ToppCellCOVID-19-COVID-19_Mild-Myeloid-pDC|COVID-19_Mild / Disease, condition lineage and cell class

NPC1 NIBAN3 CLCN5 AEBP1 PLXNA4 MMP11

2.99e-0519913369de61e5189d907cc969ac3043d68204f70acc0bf
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_airway_basal-Dividing_Basal|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CYP11A1 SAA1 SAA2 A2ML1 SLC4A4 GABBR1

2.99e-051991336f0c289523957258d16135c04679db379d43d28d9
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NUMBL ABCA8 PLA2R1 NLN PITPNM3 GAREM1

3.07e-0520013365ad3ea1cf1fcd4100966c5517bc7ed0a1af54317
ToppCellCOVID-19-COVID-19_Mild-Myeloid-cDC|COVID-19_Mild / Disease, condition lineage and cell class

TNFAIP8L2 MAT2A ITGAX RAB34 SEMA4A RAB32

3.07e-052001336b8f52e65813d331c49cdd5f354fdfec6fc8c339e
ToppCellMS-IIF-Myeloid-cDC|IIF / Disease, condition lineage and cell class

MAT2A ITGAX RAB34 SYNGR2 SEMA4A RAB32

3.07e-052001336620a82805619d113182d59740670c9f9b93ee924
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-T-cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

THNSL1 ITGAX SEMA4A TRAPPC14 SEC14L5

5.52e-051361335186be8e1595608004b8216892cb9c7a7f31fbb4d
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 ITGB2 KCNJ9 SEMA4A NLRC3

6.78e-05142133539ada235a46f2202c093cf2336de224a5957ed1a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Outer_Medullary_Collecting_Duct_Principal_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

VEPH1 HMGCS2 AQP2 FER1L6-AS2 SLC4A4

7.99e-051471335b66ccc710b3c04f6fc7fed69f3c892fc110e98fc
ToppCell368C-Lymphocytic-CD4_T-cell-Treg_cell_1|368C / Donor, Lineage, Cell class and subclass (all cells)

CPLANE2 PITPNM2 UBR1 TNFAIP8L2 NLRC3

8.25e-05148133580470353e12599440f711b6e107730763376d04d
ToppCelldroplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Hematologic-leukocyte|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 ITGB2 KCNJ9 SEMA4A NLRC3

9.35e-051521335bfc7ef4ee26165d18ac4f475a9519e8d52453ba2
ToppCellPND10-Immune-Immune_Myeloid-DC-cDC2|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGAX ITGB2 SLC13A4 SYNGR2 SEMA4A

9.35e-05152133527718e92715ddc80f28b457a5d6d6a3ac2b205d2
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_Hsd17b2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADM LLGL2 ABCB11 TMEM163

1.02e-0481133420796e59cdeb398e7772f4356578d74a33405f71
ToppCellBasal_cells-Donor_05|World / lung cells shred on cell class, cell subclass, sample id

IRS4 MS4A12 TKTL1 EDNRA SLC4A4

1.03e-04155133530accc72a6a914ae0c4d52b373ea1c9a98efbf22
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 NUMBL ITGAX LLGL2 TMEM163

1.09e-0415713355d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 ITGAX ITGB2 RAB44 GABBR1

1.09e-0415713358c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 ITGAX ITGB2 RAB44 GABBR1

1.09e-041571335ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CYP11A1 ITGAX ITGB2 RAB44 GABBR1

1.09e-041571335008f938a338f43c3251dcac574f1b4f689926c71
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 NUMBL ITGAX LLGL2 TMEM163

1.09e-041571335ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell356C-Fibroblasts-Fibroblast-D-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

B4GALNT4 RPS6KA1 IRF6 DCLK2 S1PR4

1.16e-041591335299e2162a82e31196d7f3a110c2db622349edfff
ToppCellSubstantia_nigra-Endothelial-ENDOTHELIAL_TIP|Substantia_nigra / BrainAtlas - Mouse McCarroll V32

WNT6 S1PR2 HMGCS2 SLC13A4 ABCB11

1.16e-041591335cb2470b288c13e454a2a80115b0d5613b3f718e6
ToppCell356C-Fibroblasts-Fibroblast-D|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

B4GALNT4 RPS6KA1 IRF6 DCLK2 S1PR4

1.16e-0415913350a3a363b30a8c741e1a3e2525725108d03c21776
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1-cDC1_mature|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGAX RAB34 SYNGR2 SEMA4A RAB32

1.16e-041591335a5fee9e7ee00c20a4ba30b0dfaf1189fb109a1af
ToppCellCOVID_non-vent-Lymphocytic-Dendritic-pDC|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NPC1 NIBAN3 CLCN5 AEBP1 PLXNA4

1.19e-04160133561f4cb4eb4313d8318aadbb99595a6cb7fd919f7
ToppCellCOVID_non-vent-Lymphocytic-Dendritic|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

NPC1 NIBAN3 CLCN5 AEBP1 PLXNA4

1.19e-04160133534b4f710cfcb6ec370b8b074f3cbfe272f392cec
ToppCellfacs-Skin-Anagen-3m-Epithelial-inner_bulge|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CPLANE2 B4GALNT4 CDHR2 SAA2 SYNGR1

1.23e-0416113358d2987271da52fd8353557ac6faa4f7a4be0ed2a
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Natural_Killer|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAX ITGB2 TYK2 SEMA4A NLRC3

1.26e-0416213350321fc954ae4ad67ca438cbbc84632562d222188
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-NK_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGAX ITGB2 TYK2 SEMA4A NLRC3

1.26e-0416213355731f9514434296132df4bc86f78ce87b07cdeca
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid-macrophage|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB2 RAB44 SAA1 SAA2 SEMA4A

1.30e-04163133557f02f2b9ce940a2962bb57cd8d02eb67b6f44a3
ToppCellImmune_cells-B_cell|World / Lineage and Cell class

CYP11A1 SIPA1 NIBAN3 RAB34 TMEM163

1.30e-0416313353a02465de7c2f7cea227e289fb082a1fb6400301
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB2 RAB44 SAA1 SAA2 SEMA4A

1.30e-041631335155ac52a34e0d55545aab8a3e4162fc4c387e697
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Myeloid-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ITGB2 RAB44 SAA1 SAA2 SEMA4A

1.30e-041631335c132fb5b56186a10d33ae5ce17b2a7e670d52f79
ToppCellPND07-Immune-Immune_Myeloid-DC-cDC1|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

ITGAX RAB34 SYNGR2 SEMA4A RAB32

1.34e-041641335662f74ad2656c0af158dbf9eb81d5bf70f54e529
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPLANE2 TKTL1 PKD1L3 EDEM3 SYVN1

1.34e-041641335b92e7c91910d518627376166c6ea9ed333b3d07e
ToppCelldroplet-Lung-18m-Hematologic-lymphocytic-plasma_cell-plasma_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CPLANE2 TKTL1 PKD1L3 EDEM3 SYVN1

1.34e-041641335a1e43c6b3e2553f5604100db6e92bf244b70c36d
ToppCellNS-critical-d_07-13-Myeloid-pDC|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

SLC7A6 NIBAN3 AEBP1 PLXNA4 MMP11

1.37e-04165133517d5c4a111d9b5400780bc5e7b93ce2f5d69ceb7
ToppCellfacs-Spleen-nan-24m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIBAN3 HNRNPD CIRBP ADM TMEM163

1.37e-041651335966ed14d479e0f1a507f46d08408aa99bd7682ae
ToppCell356C-Fibroblasts-Fibroblast-D|356C / Donor, Lineage, Cell class and subclass (all cells)

B4GALNT4 NUMBL ABCA8 PLA2R1 DCLK2

1.41e-0416613357286a37b2827f3747469ffd0d76cbe81116db7ee
ToppCell356C-Fibroblasts-Fibroblast-D-|356C / Donor, Lineage, Cell class and subclass (all cells)

B4GALNT4 NUMBL ABCA8 PLA2R1 DCLK2

1.41e-0416613357c2eee0a4f45795a956acf936b85bdb35f1b1624
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 RPS6KA1 ITGB2 SEMA4A S1PR4

1.45e-04167133510c9fab3573c2948081aac2cec1798e46e59e38a
ToppCellfacs-Spleen-nan-24m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NIBAN3 HNRNPD CIRBP ADM TMEM163

1.45e-0416713359a8e291c082d7c26bab21df77bd36ce927032a70
ToppCell3'-Child09-12-SmallIntestine-Hematopoietic-B_cells-LZ_GC_cell|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

S1PR2 VNN2 SYNGR2 SEMA4A SYVN1

1.49e-04168133508eb1284f9b8bd3e0e4b21bfc2bbee01d35a0bd7
ToppCelldroplet-Thymus-nan-3m-Lymphocytic-DN4_thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 RPS6KA1 ITGB2 SEMA4A S1PR4

1.54e-0416913352de213b083f57f47be58427c0ce127fee9f85caa
ToppCelldroplet-Lung-nan-3m-Myeloid-basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 TKTL1 RAB44 GABBR1 S1PR4

1.54e-041691335da607c1d068038d5a3d1117f6aa6e4c6f3552e97
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ITGAX RAB44 VNN2 ABCB11 S1PR4

1.54e-0416913352e15a9317da4017757d184f7cc91bd66b072ac51
ToppCelldroplet-Lung-nan-3m-Myeloid-Basophil|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CYP11A1 TKTL1 RAB44 GABBR1 S1PR4

1.54e-041691335a14b46231e079a0fd9f3ca13d5d48113be76fd0f
ToppCellImmune_cells-Dendritic_cells|World / Lineage and Cell class

TNFAIP8L2 ITGAX ITGB2 SYNGR2 TMEM163

1.58e-041701335094dc211d80c89ecb1010855f1fe6eeb71bf0e20
ToppCellfacs-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-myeloid_dendritic_type_1|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFAIP8L2 RTL5 ITGAX ITGB2 SEMA4A

1.58e-0417013356686d1797988216c0d9417f21a2537369abce410
ToppCellfacs-Marrow-T-cells-3m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 ITGAX CLCN5 SNX18 TMEM163

1.62e-0417113356a0fafb8fd9fc7671618eeb2bf528ce8ce86b794
ToppCellfacs-Lung-18m-Hematologic-myeloid|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TNFAIP8L2 ITGAX ITGB2 SEMA4A RAB32

1.62e-0417113354ad28ecfde3d529a09b80be908c446bd5274518e
ToppCellfacs-Marrow-T-cells-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPC1 ITGAX CLCN5 SNX18 TMEM163

1.62e-041711335e02b5831768dbb1b68998b672e55c9680ab0cc86
ToppCellImmune_cells-B_cell|Immune_cells / Lineage and Cell class

CYP11A1 SIPA1 NIBAN3 ADM TMEM163

1.67e-041721335b646894b691a99bf2742bd9da8e578dff0e87f1f
ToppCellfacs-Liver-Non-hepatocytes-24m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 WNT6 ITGAX ITGB2 SYNGR2

1.67e-04172133566823536288c7009ce01b5177794a3e874e94570
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFAIP8L2 B4GALNT4 CYP11A1 RAB44 SEMA4A

1.67e-041721335c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCellPND10-Immune-Immune_Myeloid-Granulocytic-Basophil|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TNFAIP8L2 B4GALNT4 CYP11A1 RAB44 SEMA4A

1.67e-041721335953b05f776348cff784e79c93df65841939d880f
ToppCelldroplet-Lung-21m-Hematologic-lymphocytic-mature_NK_T_cell-mature_NK_T_cell_l44|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NUMBL TKTL1 ITGAX TYK2 S1PR4

1.71e-041731335b6bb2a136a40f0946bbcde8d5972d3f059d080c7
ToppCellfacs-Lung-EPCAM-18m-Myeloid|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 ITGAX ITGB2 SEMA4A RAB32

1.71e-04173133550b25b7f8f29b60c22782a4492fe4b089fe7d69d
ToppCellfacs-Aorta-Heart-3m-Myeloid|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TNFAIP8L2 RPS6KA1 ITGAX ITGB2 RAB32

1.71e-041731335513b4d31bcfb269556c6b4cc389865fb12e52c4f
ToppCellAdult-Epithelial-basal_cell-D231|Adult / Lineage, Cell type, age group and donor

FRMPD4 WNT6 LGR4 SLC4A4 MMP11

1.76e-041741335a4f98afe7d1cc2617f6f7bc8092c41df57474b30
DiseaseCoffin-Lowry syndrome (implicated_via_orthology)

RPS6KA1 RPS6KA3

1.15e-0441302DOID:3783 (implicated_via_orthology)
Diseaseserum amyloid A protein measurement

SAA1 SAA2

2.86e-0461302EFO_0004728
Diseaserosacea severity measurement

RPS6KA1 SAA1 SAA2 KCNJ6 DCLK2

4.98e-041471305EFO_0009180
Diseasehypertension (biomarker_via_orthology)

CYP11A1 AQP2 EDNRA ADM SLC4A4 GABBR1

5.23e-042271306DOID:10763 (biomarker_via_orthology)
Diseaseamnestic disorder (implicated_via_orthology)

IRS4 IRS2

6.80e-0491302DOID:10914 (implicated_via_orthology)
Diseaseegg allergy measurement

ABCB11 ITIH6

6.80e-0491302EFO_0007018
Diseasenephrogenic diabetes insipidus (implicated_via_orthology)

AQP2 SLC4A4

8.47e-04101302DOID:12387 (implicated_via_orthology)
Diseasealkaline phosphatase measurement

B4GALNT4 ACACB NUMBL RPS6KA3 DOK7 S1PR2 PKD1L3 EDEM3 ABCB11 SLC16A11 GABBR1 SYNGR4

1.80e-03101513012EFO_0004533
Diseasegrowth-regulated alpha protein measurement

OR10J3 OR10J6P KCNJ6

1.85e-03551303EFO_0008146
Diseasemetabolic syndrome

NPC1 SIPA1 BCDIN3D ABCB11 DCLK2

1.96e-032001305EFO_0000195
Diseaseserum amyloid A-1 protein measurement

SAA1 SAA2

2.81e-03181302EFO_0008282
Diseasecarcinoma (implicated_via_orthology)

S1PR2 SLC30A7 LLGL2

2.86e-03641303DOID:305 (implicated_via_orthology)
Diseaseglomerulonephritis (biomarker_via_orthology)

ITGB1 ADM

3.47e-03201302DOID:2921 (biomarker_via_orthology)
Diseasecerebellum white matter volume change measurement, age at assessment

ABCA8 SYVN1

3.47e-03201302EFO_0008007, EFO_0021498
DiseaseCrohn's disease

EPHB4 IRF6 TYK2 PLA2R1 PER3 TBC1D1 SYVN1

3.48e-034411307EFO_0000384

Protein segments in the cluster

PeptideGeneStartEntry
FEVVLTSLFRASSRF

URB2

971

Q14146
SIAFSRAVFAEFLAT

AQP2

6

P41181
FVETSFTTLETRAFG

CPN2

56

P22792
AESDFASTFRLLTVF

COPS7A

56

Q9UBW8
GRDSSIHDDFVTTFF

AEBP1

461

Q8IUX7
LSSFLSQFGRSVFDI

BCDIN3D

146

Q7Z5W3
SEGTDLFSFFRDVGL

A2ML1

666

A8K2U0
DGVRVGFFQLFRFSS

ABCB11

41

O95342
EAFATGRAAATSIFE

ABCB11

381

O95342
SDSSERLFSFGVIAD

ADPRM

11

Q3LIE5
DFTTFRGTELSFLVT

EDNRA

36

P25101
VFGVSGEEASRFFAV

CDH23

66

Q9H251
LANSISDFFRLFSAG

ARMCX3

241

Q9UH62
FLGADTARLDVASEF

ADM

16

P35318
FLDAVVFGGEDFRAS

CLYBL

196

Q8N0X4
AFDASRTSFAREGSF

NUMBL

211

Q9Y6R0
FSVDFRADFSESVSG

RC3H2

811

Q9HBD1
EDFRLAGAFSSDTSF

RAB3GAP1

966

Q15042
GAFVVFDISRSSTFE

RAB32

101

Q13637
AVSSLTGENVREFFF

RAB34

196

Q9BZG1
GFVTREDLAVAKFSF

RAB44

61

Q7Z6P3
ELTAFRVDSAGFGDS

ITGAX

26

P20702
ITSDFRIGFGSFVEK

ITGB1

176

P05556
TRLLVFSTDAGFHFA

ITGB1

271

P05556
GFVAAFLFSIETETT

KCNJ9

106

Q92806
VSSFLAGRQAFTDFL

NIBAN3

621

Q86XR2
FAERFFALFDSDRSG

NOX5

61

Q96PH1
DFTVASPAEFVTRFG

ACACB

241

O00763
FTLASDFEIGHFFRE

NAP1L4

311

Q99733
AGFFSAFVRTVTAFT

OR9Q2

151

Q8NGE9
TAGFFISLTETALIF

OR10X1

166

Q8NGY0
GFLRDETGDFTASFL

SLC16A11

396

Q8NCK7
FDFTSRVIGFTVLTE

LLGL2

326

Q6P1M3
SRRAIFDLFTESGVS

NLRC3

471

Q7RTR2
ESFAAAGFGSFELVS

EPHB4

926

P54760
LNGFVSAFLFSIETE

KCNJ6

136

P48051
DAAFAFASLAIVFSS

GABBR1

831

Q9UBS5
LFRGFSFVAITSDDE

RPS6KA3

381

P51812
AFIEEGTFLFTSESV

MAT2A

11

P31153
FAALSRFTGATIFEE

EDEM3

236

Q9BZQ6
GLVFAISSDRFRSFD

DCLK2

86

Q8N568
LAASFFSFRVSQDAA

HMGCS2

416

P54868
DTFVAVFSFLSGRLV

PER3

131

P56645
FVDDLFETIFSTAHR

PLXNA4

1691

Q9HCM2
ATFFLSAAGFEFLRL

OR14J1

246

Q9UGF5
FELLTSSFILVGFSD

OR2W6P

11

Q8NHA6
AFTVAGFDLTFITLS

OR52A1

206

Q9UKL2
FAVFSIAVSSDGREV

DCAF11

266

Q8TEB1
RFIGLSEDVISFFVT

GAREM1

821

Q9H706
EVRFFDVFGFSETAG

VEPH1

681

Q14D04
AGFLAVFSSESAIFL

LGR4

621

Q9BXB1
ILAFGTGVEFVRFTS

NRM

16

Q8IXM6
EFVVFSIDGSFAASV

PITPNM2

1106

Q9BZ72
EDRAALLRTFSFLGF

OAZ1

181

P54368
TRRVSFADSFGFNLV

PPP1R3A

61

Q16821
FLSSFSETVAFFLGA

NPC1

736

O15118
QGFTGRFVFSLDTSV

IGHV7-4-1

81

A0A0J9YVY3
SDSFFFIEVGRSAVT

IRS2

251

Q9Y4H2
TRLLVFATDDGFHFA

ITGB2

256

P05107
TDAFLFLFSFTDRAS

CPLANE2

136

Q9BU20
FALFGVFALASISSV

DUOXA2

216

Q1HG44
VFSIFTSSEADVFAG

CDHR2

986

Q9BYE9
RTAQLFEGSFFFSRS

FER1L6-AS2

106

Q96M78
VSFIFGDFALDDGIS

FRMPD4

651

Q14CM0
SFFAALVAAFTLRSI

CLCN5

351

P51795
GDISDDLFRFAFESI

CYP11A1

196

P05108
VELLFAAFFTTASAS

CYP26C1

291

Q6V0L0
GSGFFVFSRLEVTRA

IGHE

381

P01854
RVSLFSLAFGDDADF

ITIH6

421

Q6UXX5
SFVSTFSFQGLRLDE

GBF1

766

Q92538
ATVEGFDAYFTSRTL

GRM7

341

Q14831
GATFKSLRFIDVEFS

CRYBG1

1486

Q9Y4K1
VFFLSSAEGEQISFL

DOK7

181

Q18PE1
RTSTGIRAVDFFGAF

SEC24C

756

P53992
RTDATVSVFLGFLLF

SLC13A4

411

Q9UKG4
FEQSASLDIRSFFGF

SEC14L5

126

O43304
SLDIRSFFGFENALE

SEC14L5

131

O43304
FAREGSAFITLSASV

S1PR2

106

O95136
ASTFSLLFTAGERFA

S1PR4

131

O95977
NFVAAGFTTFDLISR

EPHA6

981

Q9UF33
SFFAAARAAVSAFPT

IRS4

1091

O14654
FSGDFTRSFDSGSVR

IRF6

406

O14896
STFVTEFLFEGFSSF

OR10J3

6

Q5JRS4
LTEVTEFVFLGFSRF

OR10J6P

6

Q8NGY7
LISFSFREVLGFAST

MS4A12

111

Q9NXJ0
ASFDAVSTIRGELFF

MMP11

296

P24347
RSRGFGFVLFKESES

HNRNPD

136

Q14103
ERVAFLISFFTGEAK

RTL5

186

Q5HYW3
AFTVFRDDFSPRFVA

SYVN1

91

Q86TM6
GVAAFRAFLKTEFSE

RGS8

66

P57771
SEFSVKRRFSDFLGL

SNX2

176

O60749
VSSRSFFSFLGEAFD

SAA2

16

P0DJI9
SFTIIRDDAFAGLFH

LGI2

96

Q8N0V4
FIGTSVSTFSFRIHE

POFUT2

381

Q9Y2G5
ASEFDFFERLHTSRV

SEMA4A

251

Q9H3S1
RGAFFTSLRLESFTS

PKD1L3

1441

Q7Z443
RVASTFIRFGSFEIF

SELENOO

246

Q9BVL4
DAGIFFTRAVQFTEE

SH3GLB2

11

Q9NR46
GFVTHVERFTFAETA

SIPA1

706

Q96FS4
RFTGVFAFGLFATDI

PLPPR1

126

Q8TBJ4
NAFLLEELFAFGSSV

PLA2R1

1296

Q13018
VSSRSFFSFLGEAFD

SAA1

16

P0DJI8
FDEISFVNFARGTTT

SSRP1

371

Q08945
VFSVAGFAFSIFESD

ABCA8

1146

O94911
TGDSRFSVVLVDFES

B4GALNT4

851

Q76KP1
TLFGEGFRAFVTDRD

ATAD3B

231

Q5T9A4
SRGFGFVTFENIDDA

CIRBP

46

Q14011
DFARFSGTNVETDFV

NLN

511

Q9BYT8
TFRGFISRDGFNFTE

VNN2

336

O95498
GAASAAFNSTREFLF

ZIC3

106

O60481
FSLEGSGISFADLFR

RIN2

156

Q8WYP3
ALSFGEVDFTFEAAV

TNFAIP8L2

101

Q6P589
TFSVAFQALRTGLFE

TRAPPC14

451

Q8WVR3
RFSTFVKSGGEAFVL

SNX18

231

Q96RF0
RSSGFFSSFEESDIE

TBC1D1

256

Q86TI0
FDRFIGATANFSRFT

RNASEH2C

116

Q8TDP1
GAVSRLHEFVSFEDF

UBR1

626

Q8IWV7
DIRETAFVFAITAAG

WNT6

101

Q9Y6F9
SDSVVSASREIAAFF

NME6

131

O75414
RIFNDSDFTGFLTVE

THNSL1

446

Q8IYQ7
AARAAIAFSFFSIFT

SYNGR1

146

O43759
ADSARAAITFSFFSI

nan

141

A8MWL6
GADSVRAAITFSFFS

SYNGR2

141

O43760
TRVFEGVFSLIVFSS

SYNGR4

26

O95473
STVEFVTAAVGVFSF

PLAAT1

141

Q9HDD0
SLGRFDFDVSDFFLF

PITPNM3

386

Q9BZ71
IFTAFFIFSEGVERA

SLC30A7

116

Q8NEW0
GLNASIFASSRLFFV

SLC7A6

331

Q92536
IFASSRLFFVGSREG

SLC7A6

336

Q92536
SSDILEFGQEAFRFT

TMEM81

106

Q6P7N7
RLAVFFSDSFVVAEA

PIGO

556

Q8TEQ8
FSDSFVVAEARATPF

PIGO

561

Q8TEQ8
TRFTEEGFSSLISFI

SLC4A4

581

Q9Y6R1
RASGAARFSVIFLFF

TMEM218

31

A2RU14
ASAFGFAFDAILDVL

TMEM163

116

Q8TC26
FTSGISGFLADEFAI

ZFYVE26

671

Q68DK2
TIAFASTFAAFLTRA

TKTL1

356

P51854
FVSLVDGYFRLTADS

TYK2

416

P29597
RFTTSGEEALIFQTF

VPS13D

1936

Q5THJ4
FFSEREASFVLHTIG

RPS6KA1

506

Q15418