Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctioncytoskeletal protein binding

KIF21B MAP7D3 CALD1 MARK1 SYNE1 KTN1 CEP290 NUMA1 CKAP5 HOOK1 MICALL2 ANKRD1 TUBGCP3 LIMCH1 CACYBP PLEKHH2 SCIN

4.46e-05109910317GO:0008092
GeneOntologyMolecularFunctionmicrotubule minus-end binding

CEP290 NUMA1 TUBGCP3

5.80e-05151033GO:0051011
GeneOntologyMolecularFunctionhelicase activity

ATRX CHD2 RUVBL2 DICER1 DDX54 HLTF

1.70e-041581036GO:0004386
GeneOntologyMolecularFunctioncatalytic activity, acting on DNA

ATRX POLA1 CHD2 RUVBL2 DICER1 HLTF DNMT3B

4.19e-042621037GO:0140097
GeneOntologyBiologicalProcessmicrotubule-based process

KIF21B ENKUR MAP7D3 ATRX MARK1 IFT172 KTN1 CEP290 NUMA1 CKAP5 DICER1 CATSPER1 SUGT1 HOOK1 CCDC42 TUBGCP3 TTL

1.83e-05105810317GO:0007017
GeneOntologyCellularComponentsperm principal piece

ENKUR IFT172 CATSPER1 CCDC42

6.99e-05441054GO:0097228
DomainSGS

SUGT1 CACYBP

2.90e-0521012PS51048
DomainSGS

SUGT1 CACYBP

2.90e-0521012PF05002
DomainSGS_dom

SUGT1 CACYBP

2.90e-0521012IPR007699
DomainADD

ATRX DNMT3B

1.73e-0441012IPR025766
DomainADD

ATRX DNMT3B

1.73e-0441012PS51533
DomainHelicase_C

ATRX CHD2 DICER1 DDX54 HLTF

2.88e-041071015PF00271
DomainHELICc

ATRX CHD2 DICER1 DDX54 HLTF

2.88e-041071015SM00490
DomainHelicase_C

ATRX CHD2 DICER1 DDX54 HLTF

3.00e-041081015IPR001650
DomainHELICASE_CTER

ATRX CHD2 DICER1 DDX54 HLTF

3.13e-041091015PS51194
DomainHELICASE_ATP_BIND_1

ATRX CHD2 DICER1 DDX54 HLTF

3.13e-041091015PS51192
DomainDEXDc

ATRX CHD2 DICER1 DDX54 HLTF

3.13e-041091015SM00487
DomainHelicase_ATP-bd

ATRX CHD2 DICER1 DDX54 HLTF

3.27e-041101015IPR014001
DomainSNF2_N

ATRX CHD2 HLTF

6.79e-04321013IPR000330
DomainSNF2_N

ATRX CHD2 HLTF

6.79e-04321013PF00176
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

RANBP2 ELOA2 CALD1 ATRX SYNE1 KTN1 NUMA1 DNAJC18 CHD2 CTAGE6 RYR2 ACSM3 HOOK1 FAM50A TNN ITSN2 DLAT LIMCH1 MPHOSPH10 CTAGE4 ATP2A2 THRAP3 DOP1A DNMT3B

1.54e-1114421092435575683
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

RANBP2 EDF1 CDV3 SERBP1 MAP7D3 CALD1 POLA1 KTN1 CKAP5 RUVBL2 CDC42BPB DICER1 FAM50A MPHOSPH10 CACYBP ATP2A2 THRAP3

1.18e-107241091736232890
Pubmed

The RNA-mediated estrogen receptor α interactome of hormone-dependent human breast cancer cell nuclei.

RANBP2 EDF1 SERBP1 ATRX DNAJC8 SYNE1 PARP2 KTN1 INTS1 CKAP5 APLP2 CHD2 CDC42BPB DICER1 MICALL2 ITSN2 HLTF LIMCH1 MPHOSPH10 SGF29 MRPL49 ATP2A2

1.27e-0914971092231527615
Pubmed

Gain of Additional BIRC3 Protein Functions through 3'-UTR-Mediated Protein Complex Formation.

RANBP2 SERBP1 ATRX DNAJC8 POLA1 SYNE1 KTN1 NUMA1 CKAP5 APLP2 PSMD12 RUVBL2 DICER1 DDX54 DLAT GALNT5 CACYBP ATP2A2 THRAP3 SNX2 GOLGA4

3.06e-0914251092130948266
Pubmed

Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.

ATRX DNAJC8 SYNE1 KTN1 DNAJC18 CDC42BPB DICER1 FAM171A1 PASK SENP1 SUGT1 NDUFAF1 TUBGCP3 DDX54 DLAT SDF4 CACYBP MRPL49 ATP2A2 SNX2 GOLGA4

6.44e-0914871092133957083
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

RANBP2 EDF1 CDV3 SERBP1 CALD1 KTN1 NUMA1 CKAP5 VPS13D SUGT1 LIMCH1 SNX2 GOLGA4

2.87e-085681091337774976
Pubmed

BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.

RANBP2 SERBP1 MAP7D3 CALD1 DNAJC8 KTN1 NUMA1 CKAP5 PSMD12 RUVBL2 FAM171A1 CACYBP ATP2A2 GOLGA4

4.99e-087081091439231216
Pubmed

The human cytoplasmic dynein interactome reveals novel activators of motility.

RANBP2 EDF1 CDV3 SERBP1 MAP7D3 CALD1 CEP290 CKAP5 RUVBL2 SENP1 SH2D4A SUGT1 HOOK1 ITSN2 SNX2

7.39e-088531091528718761
Pubmed

H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.

RANBP2 MAP7D3 ATRX PARP2 KTN1 CEP290 INTS1 NUMA1 CKAP5 CHD2 SP110 RUVBL2 DDX54 HLTF ZCCHC7 SGF29 ATP2A2 THRAP3

1.12e-0712941091830804502
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

RANBP2 SERBP1 POLA1 INTS1 NUMA1 CKAP5 CHD2 PSMD12 DICER1 DDX54 DLAT MPHOSPH10 ATP2A2

1.44e-076531091322586326
Pubmed

SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.

CDV3 SERBP1 MAP7D3 CALD1 DNAJC8 KTN1 NUMA1 RUVBL2 SUGT1 CACYBP THRAP3 SNX2

1.66e-075491091238280479
Pubmed

Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.

RANBP2 CEP290 APLP2 PSMD12 CDC42BPB FAM171A1 CADM1 SH2D4A SUGT1 DDX54 SDF4 CACYBP MAPK9 SCIN ATP2A2 GOLGA4

1.81e-0710491091627880917
Pubmed

Assembly of the U5 snRNP component PRPF8 is controlled by the HSP90/R2TP chaperones.

RANBP2 EDF1 CDV3 SERBP1 POLA1 KTN1 NUMA1 CKAP5 RUVBL2 FAM50A DDX54 HLTF DLAT CACYBP MRPL49 ATP2A2 THRAP3 GOLGA4

4.16e-0714151091828515276
Pubmed

BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.

RANBP2 MAP7D3 CALD1 CKAP5 PSMD12 LIMCH1 CACYBP SNX2

4.31e-07216109831519766
Pubmed

Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.

RANBP2 SERBP1 ACADL MARK1 KTN1 CKAP5 PSMD12 RUVBL2 CDC42BPB RYR2 FABP7 SUGT1 DLAT CACYBP ATP2A2 THRAP3

5.41e-0711391091636417873
Pubmed

Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.

EDF1 SERBP1 DNAJC8 NUMA1 SUGT1 HOOK1 FAM50A CACYBP QKI THRAP3

5.49e-073991091035987950
Pubmed

SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.

SERBP1 DNAJC8 PARP2 RUVBL2 CDC42BPB ZRSR2P1 DDX54 THRAP3

1.33e-06251109831076518
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

RANBP2 EDF1 CDV3 SERBP1 MAP7D3 CALD1 ATRX KTN1 NUMA1 CKAP5 SUGT1 FAM50A CACYBP SCIN

1.39e-069341091433916271
Pubmed

Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.

CDV3 CALD1 POLA1 PARP2 CEP290 INTS1 PSMD12 QSOX1 GARIN3 SCAPER PLEKHH2 QKI

1.81e-066891091236543142
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

KIF21B RANBP2 ZNF618 SYNE1 KTN1 NUMA1 CKAP5 CDC42BPB FAM171A1 SENP1 HOOK1 LIMCH1 THRAP3 GOLGA4

1.98e-069631091428671696
Pubmed

N-Terminomics for the Identification of In Vitro Substrates and Cleavage Site Specificity of the SARS-CoV-2 Main Protease.

CDV3 SERBP1 CALD1 KTN1 NUMA1 LAMC2 CDC42BPB SNX2 GOLGA4

2.12e-06360109933111431
Pubmed

Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.

RANBP2 ATRX INTS1 CKAP5 PSMD12 RUVBL2 SUGT1 TUBGCP3 HLTF THRAP3 SNX2

2.29e-065821091120467437
Pubmed

KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.

SERBP1 CALD1 ACADL MARK1 SYNE1 KTN1 CKAP5 NCAM2 ALDH1L1 CDC42BPB ITSN2 SCAPER DLAT LIMCH1 ATP2A2 THRAP3 SNX2

2.29e-0614311091737142655
Pubmed

A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.

RANBP2 EDF1 SERBP1 CALD1 PARP2 KTN1 NUMA1 PSMD12 DICER1 SUGT1 DDX54 HLTF SDF4 LIMCH1 MRPL49 ATP2A2 THRAP3

2.49e-0614401091730833792
Pubmed

BPA modulates the WDR5/TET2 complex to regulate ERβ expression in eutopic endometrium and drives the development of endometriosis.

RANBP2 CDV3 SERBP1 DNAJC8 KTN1 PSMD12 RUVBL2 QSOX1 DDX54 SGF29 ATP2A2 THRAP3

2.50e-067111091233022573
Pubmed

Two-Dimensional Fractionation Method for Proteome-Wide Cross-Linking Mass Spectrometry Analysis.

KIF21B CDV3 SERBP1 CALD1 DNAJC8 NUMA1 CKAP5 PSMD12 RUVBL2 FAM50A SCAPER THRAP3 DOP1A

2.63e-068471091335235311
Pubmed

Systematic analysis of human protein complexes identifies chromosome segregation proteins.

RANBP2 SERBP1 CALD1 DNAJC8 SYNE1 NUMA1 CKAP5 RUVBL2 SH2D4A SUGT1 MICALL2 TUBGCP3 ITSN2 SGF29 THRAP3

3.31e-0611551091520360068
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

RANBP2 EDF1 SERBP1 ATRX DNAJC8 POLA1 INTS1 NUMA1 CHD2 RUVBL2 FAM50A HLTF CACYBP THRAP3

3.60e-0610141091432416067
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MARK1 ZNF618 KTN1 CEP290 CDC42BPB VPS13D SCAPER PLEKHH2 SCIN DOP1A

3.64e-064931091015368895
Pubmed

Identifying biological pathways that underlie primordial short stature using network analysis.

RANBP2 CALD1 SYNE1 CEP290 INTS1 NUMA1 CKAP5 RUVBL2 DICER1 DDX54 SCIN ATP2A2 THRAP3 SNX2

4.03e-0610241091424711643
Pubmed

WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.

RANBP2 ATRX PARP2 INTS1 NUMA1 CHD2 RUVBL2 DDX54 HLTF

4.41e-06394109927248496
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

SERBP1 DNAJC8 SYNE1 PSMD12 RUVBL2 SUGT1 HLTF LIMCH1 MPHOSPH10 GALNT5 CACYBP PLEKHH2

4.54e-067541091235906200
Pubmed

Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.

RANBP2 POLA1 KTN1 NUMA1 CKAP5 CHD2 RUVBL2 SUGT1 TUBGCP3 DDX54 HLTF DLAT MRPL49 ATP2A2 THRAP3 GOLGA4

4.98e-0613531091629467282
Pubmed

The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.

RANBP2 POLA1 IFT172 CKAP5 PSMD12 RUVBL2 TUBGCP3 DLAT CACYBP ATP2A2 SNX2

5.49e-066381091133239621
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

RANBP2 ATRX NUMA1 CKAP5 QSOX1 PASK SH2D4A LIMCH1 ATP2A2 THRAP3 SNX2 GOLGA4

5.92e-067741091215302935
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

RANBP2 EDF1 MARK1 ZNF618 SYNE1 INTS1 APLP2 CHD2 RUVBL2 TUBGCP3 MRPL49 ATP2A2 THRAP3 DNMT3B

7.53e-0610821091438697112
Pubmed

The ubiquitin ligase Uhrf2 is a master regulator of cholesterol biosynthesis and is essential for liver regeneration.

RANBP2 SERBP1 ATRX NUMA1 THRAP3

7.84e-0686109537253089
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

RANBP2 EDF1 DNAJC8 CKAP5 PSMD12 RUVBL2 SUGT1 TUBGCP3 HLTF CACYBP QKI SGF29 ATP2A2 THRAP3

9.35e-0611031091434189442
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

RANBP2 EDF1 SERBP1 MAP7D3 CALD1 ATRX DNAJC8 KTN1 NUMA1 MPHOSPH10 ZCCHC7 ATP2A2 THRAP3

9.46e-069541091336373674
Pubmed

JNK2, a Newly-Identified SERCA2 Enhancer, Augments an Arrhythmic [Ca2+]SR Leak-Load Relationship.

MAPK9 ATP2A2

9.73e-062109233334123
Pubmed

SYNE1-QK1 SNPs, G × G and G × E interactions on the risk of hyperlipidaemia.

SYNE1 QKI

9.73e-062109232281752
Pubmed

Cumulative episodes of rejection altered myocardial sarcoplasmic reticulum Ca(2+)-ATPase and ryanodine receptor-2 mRNA expression in heart transplant recipients.

RYR2 ATP2A2

9.73e-062109220716843
Pubmed

Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.

CALD1 CEP290 FAM161B RUVBL2 PASK VPS13D SDF4 ATP2A2 THRAP3 GOLGA4

1.18e-055641091021565611
Pubmed

Proximity labelling identifies pro-migratory endocytic recycling cargo and machinery of the Rab4 and Rab11 families.

CDV3 CALD1 SYNE1 SUGT1 CACYBP SNX2 GOLGA4 IL6ST

1.21e-05339109837232246
Pubmed

PRP19 transforms into a sensor of RPA-ssDNA after DNA damage and drives ATR activation via a ubiquitin-mediated circuitry.

CALD1 POLA1 INTS1 NUMA1 CKAP5 RUVBL2 HLTF LIMCH1

1.24e-05340109824332808
Pubmed

Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.

SYNE1 INTS1 CKAP5 RUVBL2 CDC42BPB CADM1 SH2D4A SUGT1 NDUFAF1 ATP2A2

1.35e-055731091028330616
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

RANBP2 PARP2 INTS1 NUMA1 CHD2 PSMD12 RUVBL2 DDX54 HLTF MPHOSPH10 CACYBP MRPL49 ATP2A2 THRAP3 SNX2

1.59e-0513181091530463901
Pubmed

MLF2 Negatively Regulates P53 and Promotes Colorectal Carcinogenesis.

RANBP2 SERBP1 NUMA1 RUVBL2

1.60e-0548109437438558
Pubmed

The PHLPP1 N-Terminal Extension Is a Mitotic Cdk1 Substrate and Controls an Interactome Switch.

RANBP2 MAP7D3 CKAP5 SH2D4A SUGT1 LIMCH1 CACYBP

1.70e-05256109733397691
Pubmed

Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.

KIF21B CDV3 SERBP1 ATRX POLA1 INTS1 APLP2 DICER1 KMT5B FAM50A DDX54 SCAPER DLAT SGF29 CRAMP1

1.72e-0513271091532694731
Pubmed

A High-Density Human Mitochondrial Proximity Interaction Network.

MAP7D3 SYNE1 KTN1 SLC25A25 VPS13D SENP1 SUGT1 NDUFAF1 ITSN2 DDX54 DLAT MPHOSPH10 CACYBP QKI MRPL49 ATP2A2

1.73e-0514961091632877691
Pubmed

Defining the membrane proteome of NK cells.

RANBP2 SERBP1 MAP7D3 KTN1 CEP290 INTS1 CKAP5 APLP2 PSMD12 TUBGCP3 DDX54 HLTF SDF4 IL6ST

1.77e-0511681091419946888
Pubmed

LINC00240 in the 6p22.1 risk locus promotes gastric cancer progression through USP10-mediated DDX21 stabilization.

KTN1 NUMA1 CKAP5

1.97e-0517109337072811
Pubmed

A human MAP kinase interactome.

RANBP2 SYNE1 KTN1 CEP290 APLP2 CDC42BPB SH2D4A ITSN2 MAPK9

2.34e-05486109920936779
Pubmed

Serological detection of cutaneous T-cell lymphoma-associated antigens.

CEP290 CTAGE4 GOLGA4

2.36e-0518109311149944
Pubmed

Proteome-wide identification of HSP70/HSC70 chaperone clients in human cells.

RANBP2 EDF1 CDV3 CALD1 KTN1 CKAP5 PSMD12 RUVBL2 CADM1 SUGT1 FAM50A CACYBP QKI ATP2A2 THRAP3

2.43e-0513671091532687490
Pubmed

HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.

EDF1 SERBP1 KTN1 NUMA1 CHD2 RUVBL2 CDC42BPB DICER1 FAM50A TUBGCP3 DLAT SDF4 LIMCH1 QKI THRAP3

2.51e-0513711091536244648
Pubmed

The E3 ubiquitin ligase HECTD1 contributes to cell proliferation through an effect on mitosis.

SERBP1 MAP7D3 KTN1 NUMA1 CKAP5 RUVBL2 DDX54 SCAPER DLAT MPHOSPH10 SGF29

2.75e-057591091135915203
Pubmed

Proteomic analysis of exosomes from human neural stem cells by flow field-flow fractionation and nanoflow liquid chromatography-tandem mass spectrometry.

NUMA1 CARD11 THRAP3 GOLGA4

2.75e-0555109418570454
Pubmed

FBXO22 promotes leukemogenesis by targeting BACH1 in MLL-rearranged acute myeloid leukemia.

KIF21B KTN1 NUMA1 CHD2 ALDH1L1 VPS13D DDX54 LIMCH1 GALNT5

2.79e-05497109936774506
Pubmed

Current view on cellular function of S100A6 and its ligands, CacyBP/SIP and Sgt1.

SUGT1 CACYBP

2.91e-053109230656909
Pubmed

p180 promotes the ribosome-independent localization of a subset of mRNA to the endoplasmic reticulum.

POLA1 KTN1

2.91e-053109222679391
Pubmed

The cardiac ryanodine receptor, but not sarcoplasmic reticulum Ca2+-ATPase, is a major determinant of Ca2+ alternans in intact mouse hearts.

RYR2 ATP2A2

2.91e-053109229986885
Pubmed

T cell receptor/CARMA1/NF-κB signaling controls T-helper (Th) 17 differentiation.

CARD11 MAPK9

2.91e-053109223091043
Pubmed

Rbm10 regulates inflammation development via alternative splicing of Dnmt3b.

IL6ST DNMT3B

2.91e-053109229309623
Pubmed

QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.

RYR2 ANKRD1 QKI

3.28e-0520109333397958
Pubmed

Genetic and Proteomic Interrogation of Lower Confidence Candidate Genes Reveals Signaling Networks in β-Catenin-Active Cancers.

RANBP2 SERBP1 KTN1 NUMA1 PSMD12 RUVBL2 SUGT1 DDX54 DLAT LIMCH1 MPHOSPH10 CACYBP ATP2A2 THRAP3

3.62e-0512471091427684187
Pubmed

A Map of Human Mitochondrial Protein Interactions Linked to Neurodegeneration Reveals New Mechanisms of Redox Homeostasis and NF-κB Signaling.

SERBP1 CALD1 NUMA1 PSMD12 RUVBL2 DLAT CACYBP MRPL49 ATP2A2 THRAP3 SNX2

3.77e-057861091129128334
Pubmed

TBK1 phosphorylation activates LIR-dependent degradation of the inflammation repressor TNIP1.

SERBP1 MAP7D3 CALD1 SYNE1 PARP2 NUMA1 SENP1 DDX54 LIMCH1 MPHOSPH10 ATP2A2 THRAP3

4.41e-059491091236574265
Pubmed

An improved smaller biotin ligase for BioID proximity labeling.

RANBP2 CCDC168 RYR2 SENP1 SUGT1

4.44e-05123109526912792
Pubmed

Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.

RANBP2 CKAP5 APLP2 PSMD12 TUBGCP3 DLAT ATP2A2 THRAP3

4.53e-05408109833766124
Pubmed

Complementary proteomics strategies capture an ataxin-1 interactome in Neuro-2a cells.

RANBP2 SERBP1 CKAP5 PSMD12 RUVBL2 DLAT CACYBP ATP2A2 THRAP3 SNX2

4.76e-056651091030457570
Pubmed

Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.

ZNF618 SCEL SP110 RUVBL2 DICER1 PASK SENP1 KMT5B TUBGCP3 SCAPER DLAT SDF4 SGF29

4.83e-0511161091331753913
Pubmed

Large-scale mapping of human protein-protein interactions by mass spectrometry.

RANBP2 SERBP1 ATRX PSMD12 RUVBL2 CDC42BPB PASK SH2D4A NDUFAF1 HOOK1 KMT5B CACYBP ATP2A2 THRAP3

4.97e-0512841091417353931
Pubmed

A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.

RANBP2 IFT172 CKAP5 APLP2 PSMD12 DICER1 PASK DDX54 CACYBP MAPK9 QKI SNX2

5.65e-059741091228675297
Pubmed

LINC01194 recruits NUMA1 to promote ubiquitination of RYR2 to enhance malignant progression in triple-negative breast cancer.

NUMA1 RYR2

5.82e-054109235750275
Pubmed

Commitment to the regulatory T cell lineage requires CARMA1 in the thymus but not in the periphery.

CARD11 MAPK9

5.82e-054109219260764
Pubmed

Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation.

RYR2 ATP2A2

5.82e-054109222798524
Pubmed

JNK1/2 regulate Bid by direct phosphorylation at Thr59 in response to ALDH1L1.

ALDH1L1 MAPK9

5.82e-054109225077544
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

MAP7D3 PSMD12 RUVBL2 DICER1 SUGT1 FAM50A LIMCH1 CACYBP ATP2A2

5.84e-05547109937267103
Pubmed

CRISPR/Cas9-mediated Genomic Editing of Cluap1/IFT38 Reveals a New Role in Actin Arrangement.

IFT172 KTN1 ALDH1L1 SUGT1 HOOK1 CACYBP

5.89e-05213109629615496
Pubmed

Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry.

RANBP2 CDV3 ARHGAP30 ITSN2 THRAP3

6.44e-05133109515144186
Pubmed

Tumor suppressor BAP1 nuclear import is governed by transportin-1.

RANBP2 CDV3 SERBP1 CALD1 CKAP5 PSMD12 RUVBL2 HOOK1 DLAT LIMCH1 CACYBP ATP2A2 SNX2

6.49e-0511491091335446349
Pubmed

Loss of connectin novex-3 leads to heart dysfunction associated with impaired cardiomyocyte proliferation and abnormal nuclear mechanics.

SYNE1 RYR2 ATP2A2

6.55e-0525109338877142
Pubmed

Combinatorial targeting of a chromatin complex comprising Dot1L, menin and the tyrosine kinase BAZ1B reveals a new therapeutic vulnerability of endocrine therapy-resistant breast cancer.

RANBP2 SERBP1 KTN1 NUMA1 RUVBL2 TUBGCP3 DDX54 MPHOSPH10 QKI ATP2A2 THRAP3

7.36e-058471091135850772
Pubmed

ATG5 is required for B cell polarization and presentation of particulate antigens.

RANBP2 EDF1 SERBP1 KTN1 CKAP5 ARHGAP30 RUVBL2 ITSN2 DDX54 CACYBP

7.38e-057011091030196744
Pubmed

Defining the human deubiquitinating enzyme interaction landscape.

MARK1 POLA1 KTN1 PSMD12 DICER1 SUGT1 TUBGCP3 HLTF SDF4 CACYBP QKI SGF29

7.61e-0510051091219615732
Pubmed

TXLNA enhances TBK1 phosphorylation by suppressing PPM1B recruitment.

EDF1 ATRX DNAJC8 RUVBL2 CACYBP

7.67e-05138109537506885
Pubmed

Proteomic and yeast 2-hybrid screens to identify PTEN binding partners.

RANBP2 CALD1 ACADL SUGT1 CACYBP ATP2A2

8.17e-05226109637839992
Pubmed

Bardet-Biedl Syndrome Overview

IFT172 CEP290 SCAPER

8.29e-0527109320301537
Pubmed

The necdin interactome: evaluating the effects of amino acid substitutions and cell stress using proximity-dependent biotinylation (BioID) and mass spectrometry.

RANBP2 SERBP1 NUMA1 CKAP5 RUVBL2 SUGT1 CACYBP

8.46e-05330109732529326
Pubmed

A genome-wide RNAi screen identifies multiple synthetic lethal interactions with the Ras oncogene.

POLA1 LINC01599 PSMD12 C4orf54 CATSPER1 MRPL49 SNX2

8.62e-05331109719490893
Pubmed

The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.

CDV3 NUMA1 CKAP5 ZC3H11B LAMC2 APLP2 CDC42BPB

8.79e-05332109737433992
Pubmed

NudCL2 regulates cell migration by stabilizing both myosin-9 and LIS1 with Hsp90.

SERBP1 CALD1 SYNE1 MRPL49 ATP2A2 CNGB1 THRAP3

8.95e-05333109732665550
Pubmed

Post-translational modification of RNA m6A demethylase ALKBH5 regulates ROS-induced DNA damage response.

SENP1 MAPK9

9.67e-055109234048572
Pubmed

Sorcin is an early marker of neurodegeneration, Ca2+ dysregulation and endoplasmic reticulum stress associated to neurodegenerative diseases.

RYR2 ATP2A2

9.67e-055109233060591
Pubmed

Distinct isoform of FABP7 revealed by screening for retroelement-activated genes in diffuse large B-cell lymphoma.

ALDH1L1 FABP7

9.67e-055109225114248
Pubmed

Differential left-to-right atria gene expression ratio in human sinus rhythm and atrial fibrillation: Implications for arrhythmogenesis and thrombogenesis.

RYR2 ATP2A2

9.67e-055109227494721
Pubmed

Calcyclin Binding Protein/Siah-1 Interacting Protein Is a Hsp90 Binding Chaperone.

SUGT1 CACYBP

9.67e-055109227249023
Pubmed

Chromosome mapping of five human cardiac and skeletal muscle sarcoplasmic reticulum protein genes.

RYR2 ATP2A2

9.67e-05510928406504
InteractionKCNA3 interactions

RANBP2 SERBP1 MAP7D3 CALD1 DNAJC8 KTN1 NUMA1 CKAP5 CHD2 PSMD12 RUVBL2 FAM171A1 HOOK1 CARD11 CACYBP ATP2A2 GOLGA4 DOP1A

8.27e-0787110818int:KCNA3
InteractionUHRF2 interactions

RANBP2 SERBP1 ATRX ZNF618 NUMA1 CHD2 THRAP3 DNMT3B

1.23e-052001088int:UHRF2
InteractionPPEF2 interactions

SUGT1 SDF4 CACYBP ATP2A2

1.67e-05291084int:PPEF2
CytobandEnsembl 112 genes in cytogenetic band chr1q25

NPL LAMC2 QSOX1 TNN CACYBP

5.16e-051671095chr1q25
GeneFamilyX-linked mental retardation|RNA helicases

ATRX DICER1

7.50e-04116821168
GeneFamilyCTAGE family

CTAGE6 CTAGE4

1.42e-0315682907
GeneFamilyLIM domain containing

SCEL MICALL2 LIMCH1

1.42e-03596831218
GeneFamilyDNA helicases

CHD2 RUVBL2

1.83e-03176821167
GeneFamilyBardet-Biedl syndrome associated|BBSome

IFT172 CEP290

2.79e-0321682980
CoexpressionSHEN_SMARCA2_TARGETS_UP

ATRX KTN1 PSMD12 TUBGCP3 ITSN2 SCAPER HLTF LIMCH1 MAPK9 SNX2

9.77e-0642910610M29
CoexpressionGSE3982_DC_VS_EFF_MEMORY_CD4_TCELL_DN

KIF21B SYNE1 NCAM2 FABP7 PASK VPS13D MRPL49

1.58e-051971067M5475
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000

RANBP2 CDV3 SERBP1 MAP7D3 ATRX POLA1 KTN1 CEP290 CKAP5 CHD2 DICER1 FABP7 CADM1 CATSPER1 HOOK1 HECTD2 MPHOSPH10 CACYBP QKI GOLGA4

9.70e-0898910720Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RANBP2 ATRX POLA1 CEP290 CKAP5 CHD2 DICER1 CATSPER1 HECTD2 MPHOSPH10 GOLGA4

4.96e-0731110711Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_1000_K2
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500

MAP7D3 ATRX POLA1 KTN1 CEP290 CKAP5 FABP7 CADM1 HOOK1 MPHOSPH10 QKI GOLGA4

7.99e-0649810712Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_500_k-means-cluster#3

ATRX POLA1 KTN1 CEP290 CKAP5 MPHOSPH10 GOLGA4

5.39e-051921077Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_500_K3
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Flanking Eminence_top-relative-expression-ranked_2500_k-means-cluster#5

RANBP2 SERBP1 ATRX POLA1 KTN1 CEP290 NUMA1 CKAP5 CHD2 HOOK1 SDF4 MPHOSPH10 QKI GOLGA4

7.36e-0583110714Facebase_RNAseq_e10.5_Neural Epithelium Flanking Eminence_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_2500_k-means-cluster#4

CALD1 ATRX ZNF618 SYNE1 CKAP5 SP110 HECTD2 ITSN2 SCAPER TTL LIMCH1 PLEKHH2 DOP1A

9.44e-0574410713Facebase_RNAseq_e10.5_Medial Nasal Eminence_2500_K4
CoexpressionAtlasFacebaseRNAseq_e8.5_Hind Brain Neural Epithelium_top-relative-expression-ranked_1000

RANBP2 EDF1 CDV3 SERBP1 KTN1 CDC42BPB FABP7 CADM1 HOOK1 DDX54 MPHOSPH10 CACYBP MRPL49 ATP2A2 DNMT3B

1.32e-0499110715Facebase_RNAseq_e8.5_Hind Brain Neural Epithelium_1000
CoexpressionAtlasFacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_1000_k-means-cluster#4

CALD1 ATRX CEP290 CKAP5 HECTD2 ITSN2 SCAPER LIMCH1

1.34e-042981078Facebase_RNAseq_e10.5_Medial Nasal Eminence_1000_K4
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_500_k-means-cluster#5

RANBP2 SERBP1 POLA1 KTN1 CEP290 CKAP5 MPHOSPH10

1.75e-042321077Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_500_K5
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500

ATRX DNAJC8 MARK1 POLA1 ZNF618 GRK4 CEP290 CKAP5 FABP7 ACSM3 HOOK1 CCDC42 HECTD2 TTL MPHOSPH10 CACYBP QKI THRAP3

2.37e-04141410718facebase_RNAseq_e10.5_Emin_MedNas_2500
CoexpressionAtlasFacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000_k-means-cluster#2

RANBP2 SERBP1 POLA1 KTN1 NCAM2 CHD2 HOOK1 MPHOSPH10

2.58e-043281078Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000_K2
CoexpressionAtlasfacebase_RNAseq_e10.5_Emin_MedNas_2500_K1

ATRX DNAJC8 MARK1 POLA1 ZNF618 GRK4 CEP290 CKAP5 HOOK1 HECTD2 TTL MPHOSPH10 CACYBP QKI THRAP3

2.74e-04106010715facebase_RNAseq_e10.5_Emin_MedNas_2500_K1
ToppCellBiopsy_IPF-Epithelial-AT1|Biopsy_IPF / Sample group, Lineage and Cell type

ACADL LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5 PLEKHH2

3.17e-08198109875bdecbe111fededf6082b11de18b84ca308ef6d
ToppCellASK428-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC2 APLP2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5 QKI

3.17e-0819810980047a9ef7684230ac5179efea94461480e90bdaf
ToppCellASK452-Epithelial|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ENKUR KTN1 LAMC2 SCEL CADM1 HOOK1 ANKRD1 LIMCH1

3.30e-081991098e8778d4d2bc7e15b4c7989a93e5808a76738df46
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 ATRX KTN1 CKAP5 RYR2 KMT5B THRAP3

2.65e-071761097749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCelldroplet-Kidney-nan-18m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 LAMC2 SCEL SH2D4A ANKRD1 PLEKHH2 SCIN

3.32e-0718210979fc2f84bf70ad9a11c8a7326bd101e6f6cbcc33e
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 LAMC2 SCEL SH2D4A ANKRD1 PLEKHH2 SCIN

3.71e-071851097502361b041a036de024eb5fe378ca09fac9b67ee
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC2 APLP2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.48e-0719610976731fef8c148b6681d6ed38afdf23c8213e0bbbe
ToppCellcellseq-Epithelial-Epithelial_Alveolar-AT1|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

LAMC2 APLP2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.48e-0719610976856317cd0cdcb88fe54b4ae905d91e13495b1c4
ToppCellLPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-Activated_MatrixFB|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

SYNE1 RYR2 MICALL2 TRIM17 LIMCH1 PLEKHH2 IL6ST

5.67e-071971097fdb92985f7df0c280b87d3e43c2394e70786a2c7
ToppCellASK428-Epithelial-Type_1|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC2 APLP2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.67e-0719710979ae6661c307791c3f0ecd3d378e3d917565e5498
ToppCellControl_saline-Epithelial_alveolar-AT_1-AT1|Control_saline / Treatment groups by lineage, cell group, cell type

LAMC2 APLP2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

5.86e-0719810979f972f217d2c39d4c0f7d0d4227d0fffe8535b9d
ToppCellASK452-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC2 APLP2 SCEL CADM1 ANKRD1 LIMCH1 QKI

6.06e-07199109748cafe44951908d03f3c6f3e185e9cbb86fb5b3b
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMC2 SCEL CADM1 SH2D4A ANKRD1 LIMCH1 GALNT5

6.06e-071991097a270630626df614f8605abddb7dee7c4d74f6149
ToppCellParenchymal-10x3prime_v2-Epithelial-Epi_alveolar-AT1|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC2 SCEL CADM1 SH2D4A ANKRD1 LIMCH1 GALNT5

6.27e-0720010973d51aebf626dd4656ab4aac8a20d761b8062c42d
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CDV3 ATRX CHD2 SP110 ITSN2 QKI GOLGA4

6.27e-07200109712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellAT1-AT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

CALD1 LAMC2 SCEL CADM1 ANKRD1 GALNT5

4.77e-061761096f86832cfeff5b3cfffe4455c1b96a1420d48ba1e
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma|TCGA-Brain / Sample_Type by Project: Shred V9

SYNE1 NUMA1 CHD2 FAM171A1 VPS13D SCAPER

4.93e-061771096e8ab340b20cd41554c3841fe980e078e878af35f
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.26e-0617910964f6ca313b78aa93557937a046c44dcf8bcc9963c
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMC2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

5.26e-06179109604ce3673e46606f63d9c87bcba3a64c96817d812
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMC2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

5.60e-061811096b45b11428d13950369347e051d4d517efb2bd4fd
ToppCellIPF-Epithelial-ATI|World / Disease state, Lineage and Cell class

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.97e-06183109631fef35ecf30162662f24d335d8f0cceacc07039
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.97e-061831096942530449e9c6583705eeb8f6f12621daea57252
ToppCellIPF-Epithelial-ATI|IPF / Disease state, Lineage and Cell class

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

5.97e-061831096c0a3541c45bd0c587603521f392f42dd86c3c35b
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ATRX KTN1 ITSN2 ZCCHC7 THRAP3 GOLGA4

6.16e-0618410961154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_1-D175|Adult / Lineage, Cell type, age group and donor

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

6.35e-06185109632b4e68e551d435a732f253f6ad83408c759a642
ToppCellAnterior_Cingulate_gyrus_(CgG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

CALD1 FABP7 CADM1 HECTD2 QKI CNGB1

6.55e-06186109632af3f211f9ad5d5c6b86b83325cfbf2f8466b56
ToppCellControl-Epithelial-ATI|Control / Disease state, Lineage and Cell class

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

6.75e-061871096fdd1c57b61ca9392ac27661a82729f37593df63c
ToppCelldroplet-Kidney-KIDNEY-1m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MARK1 SCEL SH2D4A ANKRD1 PLEKHH2

6.75e-061871096806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_I_pneumocyte-AT1-AT1_L.0.5.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

6.96e-061881096e9cef856a96a97afac5ecafe2ee91eff0d731e01
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDV3 ATRX APLP2 HOOK1 KMT5B THRAP3

7.62e-06191109660c986d2dcbc19d9338c03da6cb5e1d92fd48f8e
ToppCellLAM-Epithelial-AT1|LAM / Condition, Lineage and Cell class

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

7.62e-06191109666875b2ec2c510489407f3e433a90cdf74a15094
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDV3 ATRX APLP2 HOOK1 KMT5B GOLGA4

7.62e-06191109609db184cb90fe282a14474d7217068c58092c6f8
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CDV3 ATRX APLP2 HOOK1 KMT5B THRAP3

7.62e-061911096973117730d6ba5f127e7a0bfabfd0ff2ca7ac131
ToppCelldroplet-Kidney-nan-3m-Epithelial-podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 SCEL SH2D4A ANKRD1 PLEKHH2 SCIN

7.85e-0619210968b625c22dda23c99654c82c529a1233e99e71b54
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

CALD1 NCAM2 RYR2 HECTD2 LIMCH1 PLEKHH2

8.33e-06194109635f132cc38ac133be01834ed0946188aa0757eb4
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

8.58e-06195109607a3ef6b0f1201fe2bcb9ea426b8f7a69beb4904
ToppCellnormal_Lung-Epithelial_cells-AT1|normal_Lung / Location, Cell class and cell subclass

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

8.58e-061951096569d1ebc5a5aa110a2430b096755ae35354040c4
ToppCell356C-Epithelial_cells-Epithelial-I_(AT1)-|356C / Donor, Lineage, Cell class and subclass (all cells)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

8.58e-061951096b65511770ed67f7447847e2187555b362988af45
ToppCellASK452|World / Donor, Lineage and Cell class of Lung cells from Dropseq

CALD1 KTN1 LAMC2 RYR2 ANKRD1 PLEKHH2

8.58e-0619510967efd9d3a3f5e7dfe9698a4143ce4a0f9bf3a862c
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMC2 SCEL CADM1 SH2D4A LIMCH1 QKI

8.83e-0619610969790340c25f446ec655f5a0b64ec3bb44ed2e1bd
ToppCellPND03-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMC2 SCEL CADM1 SH2D4A LIMCH1 QKI

8.83e-061961096b9ceceeacbcf81976ce92adf044f0d0aa132632b
ToppCell(7)_Epithelial-I_(AT1)|World / Lung cell shreds - cell class (v4) and cell subclass (v4)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

8.83e-061961096150554fa06868d29b0608189862eef6505ba757f
ToppCell368C-Fibroblasts-Fibroblast-G|368C / Donor, Lineage, Cell class and subclass (all cells)

CALD1 NCAM2 QSOX1 LIMCH1 PLEKHH2 IL6ST

9.09e-061971096156155c2f0c1a2461e45803da578af18ee221660
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

CEP290 LAMC2 SCEL SH2D4A SCAPER GALNT5

9.09e-0619710963d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell368C-Fibroblasts-Fibroblast-G-|368C / Donor, Lineage, Cell class and subclass (all cells)

CALD1 NCAM2 QSOX1 LIMCH1 PLEKHH2 IL6ST

9.09e-061971096d5d9263451f6c10cb3b9c17740183ca334e24851
ToppCellnormal_Lung-Epithelial_cells-AT1|Epithelial_cells / Location, Cell class and cell subclass

APLP2 SCEL CADM1 ANKRD1 LIMCH1 QKI

9.09e-0619710967d19b93d6853828e2a036e37c4887edb1de4503c
ToppCellASK440-Epithelial-Type_1|ASK440 / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.09e-0619710961eda2c2504451a3d626dda5c2b2b12eeaa6bca54
ToppCellASK440-Epithelial-Type_1|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.09e-061971096782449c522c9e16e72bf999a73090688a3aefe06
ToppCellASK452-Epithelial-Transformed_epithelium|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

CALD1 KTN1 LAMC2 RYR2 CADM1 PLEKHH2

9.09e-061971096b22a79a5922c865a360e2afc5506a08a512fa76a
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.36e-0619810965a85c286f79cde5811d2595a3397c6fb7685adee
ToppCellAT1-AT2_cells|World / lung cells shred on cell class, cell subclass, sample id

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.36e-061981096a5b3617ea2ed4bffba59edcf6284799c2b3bbb29
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT1|Control_saline / Treatment groups by lineage, cell group, cell type

LAMC2 APLP2 SCEL CADM1 LIMCH1 GALNT5

9.36e-06198109685f424cd9bb3117c9e322031024aabb87696ce47
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

LAMC2 SCEL SH2D4A ANKRD1 LIMCH1 GALNT5

9.36e-061981096b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCellControl_saline-Epithelial_alveolar-AT_1|Control_saline / Treatment groups by lineage, cell group, cell type

LAMC2 APLP2 SCEL CADM1 LIMCH1 GALNT5

9.36e-0619810969b161285df7a4e51618f3517cfc5b8221ba55786
ToppCellControl_saline-Epithelial_alveolar|Control_saline / Treatment groups by lineage, cell group, cell type

LAMC2 APLP2 SCEL CADM1 LIMCH1 GALNT5

9.36e-061981096532b7ef4ad46fe35ad2c6bdf89f70a17f1a2e2e2
ToppCellParenchymal-10x5prime-Epithelial-Epi_alveolar-AT1|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.63e-061991096aca81a879ef9c196bd1885eff4c63ffe6c9682b7
ToppCell(00)_Basal-(2)_GFP_FOXI1|(00)_Basal / shred by cell type by condition

CALD1 ATRX KTN1 PSMD12 LIMCH1 GOLGA4

9.63e-06199109619674e1eaeb51e4196d847cb62aa437c852951d3
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LAMC2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

9.63e-061991096d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell(02)_MMP9/10+-(2)_GFP_FOXI1|(02)_MMP9/10+ / shred by cell type by condition

CALD1 ATRX KTN1 CEP290 ITSN2 GOLGA4

9.63e-06199109618a7f9ced4364f45b184bd529f32ef02c27779d3
ToppCell(04)_Interm._basal>secr.-(2)_GFP_FOXI1|(04)_Interm._basal>secr. / shred by cell type by condition

ATRX KTN1 CEP290 PSMD12 LIMCH1 GOLGA4

9.63e-06199109653ca3861f9e00dab3f3fbefb0837857ee39ab084
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.63e-061991096c1daa481f88d5281b6b5ea8ec8bb70cc0907d613
ToppCell(03)_KRT6B+-(2)_GFP_FOXI1|(03)_KRT6B+ / shred by cell type by condition

ATRX KTN1 CEP290 ITSN2 LIMCH1 GOLGA4

9.63e-061991096c425e7975f492ed5cfcca022248adb627e1d27d4
ToppCell(05)_Secretory-(2)_GFP_FOXI1|(05)_Secretory / shred by cell type by condition

SERBP1 ATRX KTN1 PSMD12 LIMCH1 GOLGA4

9.63e-061991096d72d87e1e530ed894c0ad5e7b5b2b1d6b59fa098
ToppCellILEUM-inflamed-(8)_Fibroblast-(8)_Fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

CALD1 ATRX QSOX1 CADM1 PLEKHH2 IL6ST

9.63e-061991096615f20bf136dfef53b072667cf0e4df6a1017e05
ToppCell(01)_IL1RL1+-(2)_GFP_FOXI1|(01)_IL1RL1+ / shred by cell type by condition

CALD1 ATRX KTN1 PSMD12 LIMCH1 GOLGA4

9.63e-061991096a2f7d0cabf35b80fe239fae34a77bf9344d5d743
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

CEP290 LAMC2 SCEL SH2D4A LIMCH1 GALNT5

9.91e-0620010962dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCelldistal-2-Epithelial-Alveolar_Epithelial_Type_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.91e-062001096313ec1e53bd738a9cb48dc5b946261156f99f44b
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.91e-062001096c6f211bbadd0c9be776c58807249e06764df47dc
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

LAMC2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

9.91e-0620010968683445ad5b70748c4a1f12eb77d47623085147e
ToppCelldistal-3-Epithelial-Alveolar_Epithelial_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

9.91e-062001096ff64454a08ae8d4cc6e8f0392558460020844bbc
ToppCellBiopsy_Other_PF-Epithelial-AT1|Biopsy_Other_PF / Sample group, Lineage and Cell type

LAMC2 SCEL CADM1 SH2D4A ANKRD1 LIMCH1

9.91e-062001096b746dcc94814bcbca63c71e6451a9c5f084bcfaf
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-Myofibroblast|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

MAP7D3 CALD1 SYNE1 RYR2 ACSM3 HECTD2

9.91e-0620010968988f113708eef7d9d2a6a6c1bcfd7c8f9804d3e
ToppCellLung_Parenchyma-Control-Epithelial-Epithelial-AT1|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.91e-0620010965f7e8d8b05c90a10313775f9f126eb4ab0fe4f67
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1-3|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC2 SCEL CADM1 SH2D4A LIMCH1 GALNT5

9.91e-062001096ccd0edd483728279fe15d64be3a39e8636bf2eeb
ToppCelldistal-Epithelial-Alveolar_Epithelial_Type_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.91e-062001096cbe3e107ac16c17687d73ebb04c39d51aba1fa98
ToppCellParenchyma_Control_(B.)-Epithelial-TX-AT1|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.91e-062001096e3a80626941363bfc9d97ef906d38c97080aecb1
ToppCellBiopsy_Control_(H.)-Epithelial-AT1|Biopsy_Control_(H.) / Sample group, Lineage and Cell type

LAMC2 SCEL CADM1 ANKRD1 LIMCH1 GALNT5

9.91e-0620010963a9633f5913f12b6865fc777c84f3f3ba795a78d
ToppCellControl-Epithelial_cells-ECM-high_epithelial|Control / group, cell type (main and fine annotations)

CALD1 SCEL CADM1 ANKRD1 LIMCH1

6.18e-051701095e2023d66e70983c87dacbd6181d3426488d1fc57
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RANBP2 SYNE1 CHD2 ANKRD1 IL6ST

6.35e-0517110952e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellAT1_cells-Donor_03|World / lung cells shred on cell class, cell subclass, sample id

LAMC2 SCEL CADM1 ANKRD1 LIMCH1

6.71e-0517310953afca2a429c634af0220c1aa19ce4cf4ee3e8b3e
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACADL SCEL CADM1 LIMCH1 GALNT5

6.71e-051731095b799c06a6a5754668e789f70c0c8bc1508568575
ToppCellPND07-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CALD1 POLA1 C4orf54 RYR2 ANKRD1

6.89e-0517410959f2e253694eb5860c00528fda31c305c6de8a2a1
ToppCellControl-Epithelial_alveolar-AT_1-Differentiating_AT1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMC2 SCEL SH2D4A LIMCH1 GALNT5

7.47e-0517710959af14a056eb6d88c6f11b09f6d4c0d3448d647d5
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 SCEL SH2D4A ANKRD1 SCIN

7.47e-0517710958f0873d348f37c823294b698043319b6608b678a
ToppCellControl-Epithelial_alveolar-AT_1|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

LAMC2 SCEL SH2D4A LIMCH1 GALNT5

7.68e-051781095aa7d43c655df493f1330a5001efaa484e4a19f69
ToppCelldroplet-Kidney-nan-18m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARK1 SH2D4A ANKRD1 GALNT5 SCIN

7.68e-051781095445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RANBP2 ATRX SYNE1 KTN1 ITSN2

7.68e-05178109501dafd19de04eff459253eaa9a35debf8f3deedf
ToppCelllung|World / shred on tissue and cell subclass

APLP2 QSOX1 LIMCH1 GALNT5 CACYBP

7.68e-0517810957b1e371272328d6b6c3994382d64281ffc737db2
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

LAMC2 SCEL CADM1 ANKRD1 LIMCH1

7.88e-051791095d5763912a4ce7188535675e338799b856edb9dda
ToppCellAT1_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

LAMC2 SCEL CADM1 GALNT5 PLEKHH2

7.88e-0517910951603117b52623663458a977c94bf7f9f6c1114b8
ToppCelldroplet-Kidney-nan-3m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CALD1 MARK1 SH2D4A ANKRD1 PLEKHH2

8.09e-05180109535c73670da90cb6924e822a2426d13a675685f09
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____podocyte|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MARK1 SH2D4A TNN ANKRD1 SCIN

8.09e-0518010956327c938a4f99df9fee714e44f15ea4a4a63ae15
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMC2 SCEL CADM1 ANKRD1 LIMCH1

8.52e-051821095573771130247e869e4e58f22d4a1cb31989635cf
ToppCellB_cell_maturation-immature_B_cell|World / Lineage and Cell class

ACSM3 DDX54 ZCCHC7 SMAD1 DNMT3B

8.52e-0518210952c7c51ebc4125d8a33454ffee0b143579ce5e451
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LAMC2 SCEL CADM1 ANKRD1 LIMCH1

8.52e-0518210956cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellCOPD-Epithelial-ATI|World / Disease state, Lineage and Cell class

LAMC2 SCEL CADM1 ANKRD1 LIMCH1

8.52e-051821095e95d946a43b1579af199900bb0e3eacbb9d65300
ToppCellCOVID-19-lung-AT1|COVID-19 / Disease (COVID-19 only), tissue and cell type

LAMC2 SCEL CADM1 LIMCH1 GALNT5

8.75e-0518310957b1a385ed54f93bfe85bf0c162e42d05d516b45c
ToppCellCOVID-19-Epithelial_cells-ECM-high_epithelial|COVID-19 / group, cell type (main and fine annotations)

LAMC2 SCEL CADM1 ANKRD1 LIMCH1

8.75e-051831095dc1d380bf7564f290256cb7108063d1bd2da732b
ToppCellfacs-Lung-EPCAM-24m-Mesenchymal-Pericyte|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MAP7D3 MARK1 SCEL ANKRD1 PLEKHH2

8.75e-0518310950e8fb371d8eac777451c76f41d53577f5dfb740d
ToppCelldroplet-Kidney-nan-21m-Epithelial-Epcam____podocyte-2|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMC2 SCEL TNN ANKRD1 SCIN

8.75e-051831095877559962b2b073fc2a9f1b64a76e17895e40a97
DrugTrihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; PC3; HT_HG-U133A

KIF21B ELOA2 CALD1 ACSM3 CADM1 TNN IL6ST SMAD1

3.55e-0619410684015_UP
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

PARP2 SH2D4A KMT5B TUBGCP3 QKI SGF29 SMAD1

1.68e-0517310672084_DN
DrugMethylergometrine maleate [113-42-8]; Down 200; 8.8uM; PC3; HT_HG-U133A

CDV3 NUMA1 APLP2 DICER1 QKI SGF29 IL6ST

3.39e-0519310676704_DN
DrugNitrofural [59-87-0]; Down 200; 20.2uM; HL60; HT_HG-U133A

BEST1 NUMA1 VPS13D ACSM3 SH2D4A SCAPER IL6ST

3.39e-0519310672459_DN
DrugTalampicillin hydrochloride [39878-70-1]; Up 200; 7.8uM; PC3; HT_HG-U133A

CALD1 CEP290 NUMA1 SP110 LIMCH1 SGF29 SCIN

3.62e-0519510677254_UP
Drugestradiol, USP; Up 200; 0.1uM; MCF7; HT_HG-U133A

NUMA1 SP110 PASK VPS13D SH2D4A ATP2A2 IL6ST

3.74e-0519610676928_UP
DrugAceclofenac [89796-99-6]; Up 200; 11.2uM; PC3; HT_HG-U133A

CALD1 CEP290 NUMA1 PASK HOOK1 ATP2A2 IL6ST

3.86e-0519710672117_UP
DrugDizocilpine maleate [77086-22-7]; Down 200; 11.8uM; HL60; HG-U133A

MAP7D3 KTN1 PASK TUBGCP3 ITSN2 MAPK9 DOP1A

3.86e-0519710671386_DN
DrugMephentermine hemisulfate [1212-72-2]; Down 200; 9.4uM; PC3; HT_HG-U133A

CALD1 SYNE1 SCEL PASK SH2D4A TUBGCP3 SCAPER

3.99e-0519810677384_DN
Drugnordihydroguaiaretic acid; Down 200; 1uM; MCF7; HT_HG-U133A

ATRX NUMA1 PASK SH2D4A MICALL2 DDX54 SNX2

3.99e-0519810675220_DN
DrugHexylcaine hydrochloride [532-76-3]; Down 200; 13.4uM; MCF7; HT_HG-U133A

ZNF133 DNAJC8 CEP290 SP110 RYR2 VPS13D DDX54

4.12e-0519910676244_DN
DrugPridinol methanesulfonate salt [6856-31-1]; Down 200; 10.2uM; HL60; HT_HG-U133A

ELOA2 SYNE1 NUMA1 SP110 RYR2 QKI IL6ST

4.12e-0519910672715_DN
DrugIsocorydine (+) [475-67-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

CALD1 CEP290 NUMA1 PASK VPS13D SCAPER IL6ST

4.25e-0520010674505_DN
Diseaselung small cell carcinoma (is_implicated_in)

ATRX LAMC2 DNMT3B

1.23e-04281023DOID:5409 (is_implicated_in)
DiseaseVACTERL association (implicated_via_orthology)

IFT172 QSOX1

1.76e-0461022DOID:14679 (implicated_via_orthology)
DiseaseRetinitis Pigmentosa

BEST1 IFT172 SCAPER CNGB1

4.75e-041041024C0035334
Diseasecystic kidney disease (implicated_via_orthology)

IFT172 CEP290

5.23e-04101022DOID:2975 (implicated_via_orthology)
DiseaseDiabetic Cardiomyopathies

RYR2 ATP2A2

6.38e-04111022C0853897
DiseaseUmbilical hernia

CALD1 ZC3H11B

6.38e-04111022HP_0001537
DiseaseEmery-Dreifuss muscular dystrophy (implicated_via_orthology)

SYNE1 HOOK1

7.64e-04121022DOID:11726 (implicated_via_orthology)
DiseaseBardet-Biedl Syndrome

IFT172 CEP290

9.00e-04131022C0752166
Diseasediffuse large B-cell lymphoma

CDC42BPB ITSN2

1.05e-03141022EFO_0000403
Diseaseessential hypertension (is_implicated_in)

GRK4 ATP2A2

1.75e-03181022DOID:10825 (is_implicated_in)
Diseasepulmonary hypertension (biomarker_via_orthology)

RYR2 ATP2A2 SMAD1

2.72e-03801023DOID:6432 (biomarker_via_orthology)
DiseaseAutism Spectrum Disorders

CHD2 RYR2 DNMT3B

3.23e-03851023C1510586
DiseaseMyocardial Ischemia

APLP2 RYR2 DLAT IL6ST

3.30e-031761024C0151744

Protein segments in the cluster

PeptideGeneStartEntry
KIFEGKTVNDKIWQE

nan

76

A8MT66
GQDIDDNWVKDRKKE

SDF4

271

Q9BRK5
SEDWGKEEGQFQKRK

CATSPER1

391

Q8NEC5
AEVWKGEVSELNKQK

CTAGE4

231

Q8IX94
AEVWKGEVSELNKQK

CTAGE6

231

Q86UF2
NDVRNITKKNIEEWG

DNMT3B

626

Q9UBC3
KAGEVSREVWEKAGK

ACADL

81

P28330
GEQQWKSEKQREAEL

ANKRD1

56

Q15327
GQNNSVKEWEDKKVS

DOP1A

561

Q5JWR5
VRGQEDNKAWKLKAV

BEST1

436

O76090
DLWTQGKKTEVQKRE

APRG1

71

Q8IVJ8
IQDRSDIWAEVKKKE

CCDC42

296

Q96M95
VVNQDKSNTDKWEKD

DICER1

1386

Q9UPY3
KAVTKDEDEWKELEQ

CDV3

76

Q9UKY7
VESKEWKERGIGNVK

RANBP2

1206

P49792
DKKKEEQNRGKPNWE

QKI

131

Q96PU8
DDRKEGAVLAKKVNW

QSOX1

376

O00391
REAERKAQKEKEEWE

ITSN2

391

Q9NZM3
LDKTKNNWEDREKFE

PARP2

181

Q9UGN5
NNWEDREKFEKVPGK

PARP2

186

Q9UGN5
DRVKKEWEEAELQAK

APLP2

406

Q06481
DEWKAIQNKDRAKVE

SERBP1

291

Q8NC51
LKNVSGKIWDEDNEK

NXF3

166

Q9H4D5
MDWEERSKNGVVKDQ

MAPK9

361

P45984
QDFKEEKPQENKTWR

ELOA2

591

Q8IYF1
GFVWTAVDKEKNKEV

PASK

1011

Q96RG2
DDQGEDKKSPWQKRE

FAM171A1

866

Q5VUB5
QVKEAGIAWDKGEKR

INTS1

556

Q8N201
NKEITWLKEEGVKQD

GOLGA4

1091

Q13439
EQNGAKIVATKEWKR

KMT5B

206

Q4FZB7
QEDVEKVKSSGDWKA

HECTD2

136

Q5U5R9
WKQKQKIDDRDSDEE

DDX54

771

Q8TDD1
GQEARVQSWKEEEKK

MICALL2

686

Q8IY33
EDVETSKKWAAGQNK

EDF1

36

O60869
GTIARWEKKEGDKIN

DLAT

106

P10515
QRWEKKVGEKLSEGD

DLAT

236

P10515
NKAWVESREKQAKGD

CACYBP

211

Q9HB71
SRDNGIKKWDLDQQE

KIF21B

1521

O75037
QAWDDVVRKEKPKED

MPHOSPH10

436

O00566
EQVAKDLAKKEAEQW

FAM161B

551

Q96MY7
SVEQEENKWKVKVDE

KTN1

1156

Q86UP2
EKIWEEEKRQEQEDK

GOLGA6L6

531

A8MZA4
EKIWEEEKRQEQEDK

GOLGA6L22

506

H0YM25
FEEKKKQREIEGQWG

TUBGCP3

806

Q96CW5
EGEKRWKDLKNRVVE

PSMD12

346

O00232
TENENEKRKWVGILE

CDC42BPB

1196

Q9Y5S2
KAWDKESEPAEEVKQ

POLA1

271

P09884
GQIKLWEAKVEEVDR

PLEKHH2

851

Q8IVE3
GEEWNKAKRVAKELD

IFT172

1371

Q9UG01
KGNTELKGKSEVEEW

CADM1

181

Q9BY67
DWKKERNEGNEKPRA

FRMD1

121

Q8N878
LEQVKKLKERWGSNE

ATP2A2

26

P16615
KKWQERKEALESVEV

CKAP5

291

Q14008
DKNWKIRKEGLDEVA

CKAP5

871

Q14008
NEFEKWQEGLKDDEK

ATRX

1636

P46100
KKWAEEFNDETNVRG

ATRX

2096

P46100
RTKKVGKNEAVLEWD

IL6ST

526

P40189
VDREEEWKQGKIRKE

LINC01599

161

Q8WXQ3
KKQEKWKQEPSEDEQ

CHD2

146

O14647
KEKNAKEELIRWEEG

CEP290

1901

O15078
KEKEAERRWKEGNFN

GALNT5

451

Q7Z7M9
EWEAKQEKIKSEEIE

FAM50A

186

Q14320
AKVVWQFRGKEDLDK

NDUFAF1

121

Q9Y375
GEKEEGKKVRRQWES

CRAMP1

151

Q96RY5
EEREAVLQGLKKNWE

ENKUR

191

Q8TC29
ESEQKEEWDKDVARK

MARK1

446

Q9P0L2
TKKKKGWLDQEDQEA

MAP7D3

661

Q8IWC1
KAKREREWQKNFEES

DNAJC8

201

O75937
KEKKSENEWTQTRQG

DNAJC18

46

Q9H819
EFKRTQKNLGNWKEE

LAMC2

891

Q13753
ELEKQVWQARKEGAA

GADL1

251

Q6ZQY3
WGKEENRKAVSDQLK

HLTF

151

Q14527
DVGDNWRIKASNVKK

HOOK1

66

Q9UJC3
KGGKIQEDKEVEIWS

CCDC168

3956

Q8NDH2
QKWDGKETNFVREIK

FABP7

96

O15540
EKVKWEEVDQRIKND

GRK4

391

P32298
SWKEKEAEKREEQAP

C4orf54

946

D6RIA3
QKASRKNERKDAEGW

SCAPER

251

Q9BY12
VEKSEGQVDVEKWKF

RYR2

86

Q92736
KDKIGEEQRKTIWVD

CARD11

1136

Q9BXL7
EKQDRRWKKSFQGDD

LIMCH1

866

Q9UPQ0
RAEELGQELKAWQEK

NUMA1

1321

Q14980
EKWEVVQKQEAEGVR

ARHGAP30

781

Q7Z6I6
SAEVWNENKERREKK

GARIN3

421

Q8TC56
VAEEWVTKGKDKLDQ

NPL

66

Q9BXD5
INAKVAEWREEGKAE

RUVBL2

276

Q9Y230
AKNEIREWEAKVQQG

SNX2

446

O60749
KFQQVDEWLKTAEEK

SYNE1

3606

Q8NF91
IWIGKDANEVEKKES

SCIN

656

Q9Y6U3
SIDKKRKEFDTNGWQ

SENP1

571

Q9P0U3
EFEVEGKGRNAKNWK

SP110

501

Q9HB58
RKVEGDIWALQKDVE

MRPL49

111

Q13405
KQGDEEEKWAEKAVD

SMAD1

21

Q15797
GEKVEQKIEGKWVNE

CALD1

406

Q05682
EGIQKKETAKINWDQ

ALDH1L1

201

O75891
AKDVLDQWTDKEKAG

ACSM3

61

Q53FZ2
SDQKLWEEVGEEAKK

CNGB1

401

Q14028
KSENWGNFIAKEEEK

ZNF572

91

Q7Z3I7
WKQKIVQAGDKDLDG

SLC25A25

51

Q6KCM7
KNQEEEKSGKWEGLV

THRAP3

461

Q9Y2W1
IQEVIWQGEAKEEKK

ZNF618

71

Q5T7W0
WQGEAKEEKKAVSKD

ZNF618

76

Q5T7W0
EDQWLEKKVQGNKDH

NCAM2

636

O15394
WAQKGDRESKKADTN

TNN

601

Q9UQP3
KVAARVKAVDGDEQW

SGF29

161

Q96ES7
QDNSWIKKRPEEEKD

SCEL

41

O95171
WKKVAEKEELEQGSR

SH2D4A

146

Q9H788
NWDKLVGEIKEEEKN

SUGT1

286

Q9Y2Z0
WRKEEKKLQEGNEVD

ZC3H11B

516

A0A1B0GTU1
REEQSLAEWQGKVKE

TRIM17

166

Q9Y577
TQLEQGKETWREEKK

ZNF133

51

P52736
GKQKKKERCWEDDDN

ZCCHC7

516

Q8N3Z6
EKEEAAKKWLEEQER

ZRSR2P1

96

Q15695
NRKKEDGEGNVWIAK

TTL

136

Q8NG68
ALEEKWKNDRQQKGE

VPS13D

116

Q5THJ4