Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	kinase binding	NEDD9 RAF1 MAPK8IP1 MAPK14 ANGPT1 CADPS POLR2A SCN5A FBXW5 PLCG2 EXOC2 ITGB2 TOP2A	5.09e-05	969	74	13	GO:0019900
GeneOntologyMolecularFunction	protein kinase binding	NEDD9 RAF1 MAPK8IP1 MAPK14 ANGPT1 CADPS SCN5A FBXW5 PLCG2 EXOC2 ITGB2 TOP2A	8.16e-05	873	74	12	GO:0019901
GeneOntologyMolecularFunction	ferroxidase activity	CP HEPH	2.01e-04	6	74	2	GO:0004322
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions, oxygen as acceptor	CP HEPH	2.01e-04	6	74	2	GO:0016724
GeneOntologyMolecularFunction	peptidyl-proline 4-dioxygenase activity	P4HA2 EGLN3	3.74e-04	8	74	2	GO:0031545
GeneOntologyMolecularFunction	dynein light chain binding	DYNC1I1 DYNC1I2	8.73e-04	12	74	2	GO:0045503
GeneOntologyMolecularFunction	peptidyl-proline dioxygenase activity	P4HA2 EGLN3	8.73e-04	12	74	2	GO:0031543
GeneOntologyMolecularFunction	MAP kinase activity	MAPK14 MAPK11	1.57e-03	16	74	2	GO:0004707
GeneOntologyMolecularFunction	calmodulin binding	PHKA1 TJP1 SPTBN1 SCN5A CAMSAP2	1.64e-03	230	74	5	GO:0005516
GeneOntologyMolecularFunction	dynein heavy chain binding	DYNC1I1 DYNC1I2	1.78e-03	17	74	2	GO:0045504
GeneOntologyMolecularFunction	GABA-gated chloride ion channel activity	GABRR1 GABRR2	1.99e-03	18	74	2	GO:0022851
GeneOntologyMolecularFunction	oxidoreductase activity, acting on metal ions	CP HEPH	1.99e-03	18	74	2	GO:0016722
GeneOntologyMolecularFunction	GABA-A receptor activity	GABRR1 GABRR2	2.22e-03	19	74	2	GO:0004890
GeneOntologyMolecularFunction	mitogen-activated protein kinase kinase binding	RAF1 MAPK8IP1	2.22e-03	19	74	2	GO:0031434
GeneOntologyMolecularFunction	magnesium ion binding	LIG4 POLR2A ADPRHL1 DCK TOP2A	2.24e-03	247	74	5	GO:0000287
GeneOntologyMolecularFunction	cytoskeletal protein binding	MAGI1 MAPK8IP1 EFHC1 SPATA6L SYNE3 SPTBN1 SCN5A NUF2 DIAPH3 CAMSAP2 DYNC1I1	2.30e-03	1099	74	11	GO:0008092
GeneOntologyMolecularFunction	L-ascorbic acid binding	P4HA2 EGLN3	2.47e-03	20	74	2	GO:0031418
GeneOntologyMolecularFunction	GABA receptor activity	GABRR1 GABRR2	2.98e-03	22	74	2	GO:0016917
GeneOntologyMolecularFunction	ankyrin binding	SPTBN1 SCN5A	3.26e-03	23	74	2	GO:0030506
GeneOntologyMolecularFunction	iron ion binding	P4HA2 EGLN3 ALOX12B HEPH	3.37e-03	166	74	4	GO:0005506
Domain	GABAAa_rho_rcpt	GABRR1 GABRR2	1.55e-05	2	74	2	IPR008057
Domain	DYNC1I1/DYNC1I2	DYNC1I1 DYNC1I2	1.55e-05	2	74	2	IPR025956
Domain	Dynein_IC2	DYNC1I1 DYNC1I2	1.55e-05	2	74	2	PF11540
Domain	MULTICOPPER_OXIDASE2	CP HEPH	4.63e-05	3	74	2	PS00080
Domain	Cu-oxidase	CP HEPH	4.63e-05	3	74	2	PF00394
Domain	Cu-oxidase	CP HEPH	4.63e-05	3	74	2	IPR001117
Domain	MAPK_p38	MAPK14 MAPK11	9.24e-05	4	74	2	IPR008352
Domain	Cu-oxidase_2	CP HEPH	9.24e-05	4	74	2	IPR011706
Domain	Cu-oxidase_2	CP HEPH	9.24e-05	4	74	2	PF07731
Domain	Cu_oxidase_CS	CP HEPH	1.54e-04	5	74	2	IPR033138
Domain	Cu-oxidase_3	CP HEPH	1.54e-04	5	74	2	IPR011707
Domain	MULTICOPPER_OXIDASE1	CP HEPH	1.54e-04	5	74	2	PS00079
Domain	Cu-oxidase_3	CP HEPH	1.54e-04	5	74	2	PF07732
Domain	Cu_oxidase_Cu_BS	CP HEPH	2.30e-04	6	74	2	IPR002355
Domain	2OG-FeII_Oxy_3	P4HA2 EGLN3	8.32e-04	11	74	2	PF13640
Domain	MAP_kinase_CS	MAPK14 MAPK11	9.96e-04	12	74	2	IPR003527
Domain	MAPK	MAPK14 MAPK11	9.96e-04	12	74	2	PS01351
Domain	Quinoprot_gluc/sorb_DH	FBXW5 LRP1	9.96e-04	12	74	2	IPR011041
Domain	-	CP HEPH	1.37e-03	14	74	2	2.60.40.420
Domain	Ldl_recept_b	NID2 LRP1	1.37e-03	14	74	2	PF00058
Domain	LDLRB	NID2 LRP1	1.37e-03	14	74	2	PS51120
Domain	LY	NID2 LRP1	1.57e-03	15	74	2	SM00135
Domain	LDLR_classB_rpt	NID2 LRP1	1.57e-03	15	74	2	IPR000033
Domain	Gal_Oxase/kelch_b-propeller	ATRN KLHL10 KBTBD8	1.66e-03	59	74	3	IPR011043
Domain	BACK	KLHL10 KBTBD8 BTBD9	1.74e-03	60	74	3	SM00875
Domain	P4Hc	P4HA2 EGLN3	1.79e-03	16	74	2	SM00702
Domain	Pro_4_hyd_alph	P4HA2 EGLN3	1.79e-03	16	74	2	IPR006620
Domain	BACK	KLHL10 KBTBD8 BTBD9	1.82e-03	61	74	3	PF07707
Domain	BACK	KLHL10 KBTBD8 BTBD9	1.82e-03	61	74	3	IPR011705
Domain	2OG-FeII_Oxy	P4HA2 EGLN3	2.54e-03	19	74	2	PF03171
Domain	Kelch_1	ATRN KLHL10 KBTBD8	2.70e-03	70	74	3	PF01344
Domain	Kelch_1	ATRN KLHL10 KBTBD8	2.70e-03	70	74	3	IPR006652
Domain	FE2OG_OXY	P4HA2 EGLN3	3.10e-03	21	74	2	PS51471
Domain	Cupredoxin	CP HEPH	3.40e-03	22	74	2	IPR008972
Domain	Growth_fac_rcpt_	EPHB6 ATRN NID2 LRP1	3.42e-03	156	74	4	IPR009030
Domain	GABAA/Glycine_rcpt	GABRR1 GABRR2	3.71e-03	23	74	2	IPR006028
Domain	Spectrin	SYNE3 SPTBN1	3.71e-03	23	74	2	PF00435
Domain	GUANYLATE_KINASE_2	MAGI1 TJP1	3.71e-03	23	74	2	PS50052
Domain	GUANYLATE_KINASE_1	MAGI1 TJP1	3.71e-03	23	74	2	PS00856
Domain	Oxoglu/Fe-dep_dioxygenase	P4HA2 EGLN3	3.71e-03	23	74	2	IPR005123
Domain	EGF-like_CS	ATRN NID2 FN1 LRP1 ITGB2	3.77e-03	261	74	5	IPR013032
Domain	Guanylate_kin	MAGI1 TJP1	4.73e-03	26	74	2	PF00625
Domain	cEGF	NID2 LRP1	4.73e-03	26	74	2	IPR026823
Domain	GK/Ca_channel_bsu	MAGI1 TJP1	4.73e-03	26	74	2	IPR008145
Domain	Guanylate_kin-like_dom	MAGI1 TJP1	4.73e-03	26	74	2	IPR008144
Domain	cEGF	NID2 LRP1	4.73e-03	26	74	2	PF12662
Domain	GuKc	MAGI1 TJP1	4.73e-03	26	74	2	SM00072
Domain	Spectrin_repeat	SYNE3 SPTBN1	5.87e-03	29	74	2	IPR002017
Domain	SKP1/BTB/POZ	KLHL10 KCNV2 KBTBD8 BTBD9	6.74e-03	189	74	4	IPR011333
Domain	Spectrin/alpha-actinin	SYNE3 SPTBN1	7.11e-03	32	74	2	IPR018159
Domain	SPEC	SYNE3 SPTBN1	7.11e-03	32	74	2	SM00150
Pathway	WP_NANOPARTICLEMEDIATED_ACTIVATION_OF_RECEPTOR_SIGNALING	RAF1 MAPK14 FN1 MAPK11	4.57e-06	28	57	4	M39572
Pathway	PID_CXCR3_PATHWAY	RAF1 MAPK14 MAPK11 ITGB2	2.64e-05	43	57	4	M222
Pathway	PID_P38_MK2_PATHWAY	RAF1 MAPK14 MAPK11	7.92e-05	21	57	3	M199
Pathway	PID_LYMPH_ANGIOGENESIS_PATHWAY	MAPK14 FN1 MAPK11	1.35e-04	25	57	3	M274
Pathway	KEGG_MEDICUS_REFERENCE_TLR2_4_MAPK_SIGNALING_PATHWAY	MAPK14 TLR2 MAPK11	1.53e-04	26	57	3	M47565
Pathway	WP_RAC1PAK1P38MMP2_PATHWAY	MAPK14 ANGPT1 FN1 MAPK11	1.61e-04	68	57	4	M39456
Pathway	KEGG_EPITHELIAL_CELL_SIGNALING_IN_HELICOBACTER_PYLORI_INFECTION	MAPK14 TJP1 PLCG2 MAPK11	1.61e-04	68	57	4	M16848
Pathway	WP_FGFR3_SIGNALING_IN_CHONDROCYTE_PROLIFERATION_AND_TERMINAL_DIFFERENTIATION	RAF1 MAPK14 MAPK11	1.71e-04	27	57	3	M39838
Pathway	KEGG_LEISHMANIA_INFECTION	MAPK14 TLR2 MAPK11 ITGB2	2.01e-04	72	57	4	M3126
Pathway	WP_NONGENOMIC_ACTIONS_OF_125_DIHYDROXYVITAMIN_D3	MAPK14 TLR2 PLCG2 MAPK11	2.36e-04	75	57	4	M39568
Pathway	KEGG_MEDICUS_PATHOGEN_SHIGELLA_OSPF_TO_TLR2_4_MAPK_SIGNALING_PATHWAY	MAPK14 MAPK11	2.38e-04	6	57	2	M47766
Pathway	KEGG_VEGF_SIGNALING_PATHWAY	RAF1 MAPK14 PLCG2 MAPK11	2.48e-04	76	57	4	M1749
Pathway	KEGG_FC_EPSILON_RI_SIGNALING_PATHWAY	RAF1 MAPK14 PLCG2 MAPK11	2.88e-04	79	57	4	M11816
Pathway	REACTOME_P38MAPK_EVENTS	MAPK14 MAPK11	3.33e-04	7	57	2	MM14672
Pathway	SIG_CD40PATHWAYMAP	MAPK8IP1 MAPK14 MAPK11	3.43e-04	34	57	3	M12705
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_CASCADES	MAPK14 TLR2 PLCG2 MAPK11 ITGB2	3.98e-04	155	57	5	MM14665
Pathway	WP_HOSTPATHOGEN_INTERACTION_OF_HUMAN_CORONAVIRUSES_MAPK_SIGNALING	RAF1 MAPK14 MAPK11	4.07e-04	36	57	3	M39908
Pathway	WP_EPITHELIAL_TO_MESENCHYMAL_TRANSITION_IN_COLORECTAL_CANCER	RAF1 MAPK14 FN1 TJP1 MAPK11	4.74e-04	161	57	5	M39770
Pathway	WP_RETINOBLASTOMA_GENE_IN_CANCER	RAF1 SIN3A DCK TOP2A	4.74e-04	90	57	4	M39678
Pathway	REACTOME_RHO_GTPASE_EFFECTORS	MAPK14 NUF2 DIAPH3 MAPK11 DYNC1I1 DYNC1I2	5.77e-04	257	57	6	MM14755
Pathway	REACTOME_TOLL_LIKE_RECEPTOR_CASCADES	MAPK14 TLR2 PLCG2 MAPK11 ITGB2	6.07e-04	170	57	5	M7494
Pathway	PID_UPA_UPAR_PATHWAY	FN1 LRP1 ITGB2	6.43e-04	42	57	3	M174
Pathway	REACTOME_ACTIVATION_OF_PPARGC1A_PGC_1ALPHA_BY_PHOSPHORYLATION	MAPK14 MAPK11	7.08e-04	10	57	2	M27146
Pathway	REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS	MAPK14 MAPK11	7.08e-04	10	57	2	MM15135
Pathway	REACTOME_ACTIVATION_OF_THE_AP_1_FAMILY_OF_TRANSCRIPTION_FACTORS	MAPK14 MAPK11	7.08e-04	10	57	2	M13962
Pathway	WP_MACROPHAGESTIMULATING_PROTEIN_MSP_SIGNALING	RAF1 MAPK14 FN1 TJP1	9.42e-04	108	57	4	M48078
Pathway	PID_ANGIOPOIETIN_RECEPTOR_PATHWAY	MAPK14 ANGPT1 FN1	1.01e-03	49	57	3	M92
Pathway	REACTOME_SIGNALLING_TO_RAS	MAPK14 MAPK11	1.03e-03	12	57	2	MM14657
Pubmed	Biochemical Reduction of the Topology of the Diverse WDR76 Protein Interactome.	NID2 GTF3C1 FN1 POLR2A SPTBN1 LRP1 ZFR EXOC2	2.84e-08	219	76	8	31353912
Pubmed	Complex formation of APP with GABAB receptors links axonal trafficking to amyloidogenic processing.	MAPK8IP1 GABRR1 GABRR2	1.19e-06	10	76	3	30902970
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	ATRN ELOA P4HA2 IPO8 ELMOD2 TJP1 SPTBN1 LEMD2 LRP1 TMEM43 SIN3A ERGIC2 TOP2A	1.92e-06	1203	76	13	29180619
Pubmed	WDR76 Co-Localizes with Heterochromatin Related Proteins and Rapidly Responds to DNA Damage.	GTF3C1 TJP1 SPTBN1 ZFR SIN3A EXOC2 TOP2A DYNC1I2	2.43e-06	394	76	8	27248496
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	ELOA LIG4 GTF3C1 KIAA0825 TJP1 SPTBN1 ZFR TMEM43 DIAPH3 ATP1A2 CAMSAP2 TOP2A DYNC1I1 DYNC1I2	2.57e-06	1442	76	14	35575683
Pubmed	Protein interaction data set highlighted with human Ras-MAPK/PI3K signaling pathways.	NEDD9 ATRN MAPK14 FN1 ESD POLR2A	2.77e-06	179	76	6	18624398
Pubmed	Pharmacological targeting of the Wdr5-MLL interaction in C/EBPα N-terminal leukemia.	POLR2A SPTBN1 ZFR SIN3A TOP2A	3.39e-06	104	76	5	26167872
Pubmed	Induction of expression of growth-related genes by FGF-4 in mouse fibroblasts.	RAF1 GABRR1 GABRR2	3.59e-06	14	76	3	8649829
Pubmed	Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation.	MAPK14 MAPK11	4.71e-06	2	76	2	29357353
Pubmed	Mycobacterium tuberculosis triggers apoptosis in peripheral neutrophils involving toll-like receptor 2 and p38 mitogen protein kinase in tuberculosis patients.	MAPK14 TLR2	4.71e-06	2	76	2	15322009
Pubmed	Deletion of hephaestin and ceruloplasmin induces a serious systemic iron deficiency and disrupts iron homeostasis.	CP HEPH	4.71e-06	2	76	2	30060949
Pubmed	Gene-based interaction analysis shows GABAergic genes interacting with parenting in adolescent depressive symptoms.	GABRR1 GABRR2	4.71e-06	2	76	2	28660714
Pubmed	GABRR1 and GABRR2, encoding the GABA-A receptor subunits rho1 and rho2, are associated with alcohol dependence.	GABRR1 GABRR2	4.71e-06	2	76	2	19536785
Pubmed	Ferroxidase hephaestin's cell-autonomous role in the retinal pigment epithelium.	CP HEPH	4.71e-06	2	76	2	22342521
Pubmed	The p38alpha/beta MAPK functions as a molecular switch to activate the quiescent satellite cell.	MAPK14 MAPK11	4.71e-06	2	76	2	15824134
Pubmed	The oral iron chelator deferiprone protects against iron overload-induced retinal degeneration.	CP HEPH	4.71e-06	2	76	2	21051716
Pubmed	Convergence of Igf2 expression and adhesion signalling via RhoA and p38 MAPK enhances myogenic differentiation.	MAPK14 MAPK11	4.71e-06	2	76	2	17105766
Pubmed	p38 MAPK signaling underlies a cell-autonomous loss of stem cell self-renewal in skeletal muscle of aged mice.	MAPK14 MAPK11	4.71e-06	2	76	2	24531379
Pubmed	Cp/Heph mutant mice have iron-induced neurodegeneration diminished by deferiprone.	CP HEPH	4.71e-06	2	76	2	26303407
Pubmed	p38 Mitogen-activated protein kinase regulates chamber-specific perinatal growth in heart.	MAPK14 MAPK11	4.71e-06	2	76	2	32573492
Pubmed	Effect of p38 MAP kinases on contractility and ischemic injury in intact heart.	MAPK14 MAPK11	4.71e-06	2	76	2	19706373
Pubmed	Ablation of hephaestin and ceruloplasmin results in iron accumulation in adipocytes and type 2 diabetes.	CP HEPH	4.71e-06	2	76	2	29355933
Pubmed	Hephaestin and ceruloplasmin facilitate iron metabolism in the mouse kidney.	CP HEPH	4.71e-06	2	76	2	27991585
Pubmed	A mathematical model of CR3/TLR2 crosstalk in the context of Francisella tularensis infection.	TLR2 ITGB2	4.71e-06	2	76	2	23133361
Pubmed	Characterization of apoptotic pathway associated with caspase-independent excision of DNA loop domains.	MAPK14 TOP2A	4.71e-06	2	76	2	17362930
Pubmed	p38α and p38β mitogen-activated protein kinases determine cholinergic transdifferentiation of sympathetic neurons.	MAPK14 MAPK11	4.71e-06	2	76	2	21865449
Pubmed	Cloning and characterization of two cytoplasmic dynein intermediate chain genes in mouse and human.	DYNC1I1 DYNC1I2	4.71e-06	2	76	2	10049579
Pubmed	The N-terminal domain of human GABA receptor rho1 subunits contains signals for homooligomeric and heterooligomeric interaction.	GABRR1 GABRR2	4.71e-06	2	76	2	9153229
Pubmed	Ceruloplasmin/hephaestin knockout mice model morphologic and molecular features of AMD.	CP HEPH	4.71e-06	2	76	2	18326691
Pubmed	Hephaestin and ceruloplasmin play distinct but interrelated roles in iron homeostasis in mouse brain.	CP HEPH	4.71e-06	2	76	2	25788583
Pubmed	Counter-regulation of T cell effector function by differentially activated p38.	MAPK14 MAPK11	4.71e-06	2	76	2	24863062
Pubmed	LDL-receptor-related protein regulates beta2-integrin-mediated leukocyte adhesion.	LRP1 ITGB2	4.71e-06	2	76	2	15328156
Pubmed	Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration.	CP HEPH	4.71e-06	2	76	2	15365174
Pubmed	Elimination of the rho1 subunit abolishes GABA(C) receptor expression and alters visual processing in the mouse retina.	GABRR1 GABRR2	4.71e-06	2	76	2	12019334
Pubmed	Intrinsically active variants of all human p38 isoforms.	MAPK14 MAPK11	4.71e-06	2	76	2	17241234
Pubmed	Ceruloplasmin and hephaestin jointly protect the exocrine pancreas against oxidative damage by facilitating iron efflux.	CP HEPH	4.71e-06	2	76	2	29883959
Pubmed	The low density lipoprotein receptor-related protein mediates fibronectin catabolism and inhibits fibronectin accumulation on cell surfaces.	FN1 LRP1	4.71e-06	2	76	2	11867643
Pubmed	p38 (Mapk14/11) occupies a regulatory node governing entry into primitive endoderm differentiation during preimplantation mouse embryo development.	MAPK14 MAPK11	4.71e-06	2	76	2	27605380
Pubmed	p38 MAPK links oxidative stress to autophagy-related gene expression in cachectic muscle wasting.	MAPK14 MAPK11	4.71e-06	2	76	2	19955483
Pubmed	The activation of p38 alpha, and not p38 beta, mitogen-activated protein kinase is required for ischemic preconditioning.	MAPK14 MAPK11	4.71e-06	2	76	2	20188737
Pubmed	LRP1 is required for novobiocin-mediated fibronectin turnover.	FN1 LRP1	4.71e-06	2	76	2	30061663
Pubmed	Roles of p38α and p38β mitogen‑activated protein kinase isoforms in human malignant melanoma A375 cells.	MAPK14 MAPK11	4.71e-06	2	76	2	31661126
Pubmed	Interferon-alpha induces the growth inhibition of human T-cell leukaemia line Jurkat through p38alpha and p38beta.	MAPK14 MAPK11	4.71e-06	2	76	2	20053787
Pubmed	Iron induced oxidative damage as a potential factor in age-related macular degeneration: the Cogan Lecture.	CP HEPH	4.71e-06	2	76	2	17065470
Pubmed	Multi-copper ferroxidase deficiency leads to iron accumulation and oxidative damage in astrocytes and oligodendrocytes.	CP HEPH	4.71e-06	2	76	2	31263155
Pubmed	Mouse cytoplasmic dynein intermediate chains: identification of new isoforms, alternative splicing and tissue distribution of transcripts.	DYNC1I1 DYNC1I2	4.71e-06	2	76	2	20657784
Pubmed	Mapping HSA 3 loci in cattle: additional support for the ancestral synteny of HSA 3 and 21.	RAF1 CP ITGB2	7.99e-06	18	76	3	1783381
Pubmed	The mammalian-membrane two-hybrid assay (MaMTH) for probing membrane-protein interactions in human cells.	RAF1 TLR2 LRP1 PLCG2 ITGB2	1.17e-05	134	76	5	24658140
Pubmed	In silico prediction of physical protein interactions and characterization of interactome orphans.	RAF1 TLR2 LRP1 PLCG2 ITGB2	1.26e-05	136	76	5	25402006
Pubmed	The protein tyrosine kinase SYK regulates the alternative p38 activation in liver during acute liver inflammation.	MAPK14 MAPK11	1.41e-05	3	76	2	31780731
Pubmed	Tanshinone IIA acts via p38 MAPK to induce apoptosis and the down-regulation of ERCC1 and lung-resistance protein in cisplatin-resistant ovarian cancer cells.	MAPK14 LRP1	1.41e-05	3	76	2	21165580
Pubmed	The p38alpha/beta mitogen-activated protein kinases mediate recruitment of CREB-binding protein to preserve fast myosin heavy chain IId/x gene activity in myotubes.	MAPK14 MAPK11	1.41e-05	3	76	2	17210568
Pubmed	Consensus phosphorylation sites of human GABA(c)/GABArho receptors are not critical for inhibition by protein kinase C activation.	GABRR1 GABRR2	1.41e-05	3	76	2	9839716
Pubmed	Astrocytic p38α MAPK drives NMDA receptor-dependent long-term depression and modulates long-term memory.	MAPK14 MAPK11	1.41e-05	3	76	2	31273206
Pubmed	TGF-β1 induces endothelial cell apoptosis by shifting VEGF activation of p38(MAPK) from the prosurvival p38β to proapoptotic p38α.	MAPK14 MAPK11	1.41e-05	3	76	2	22522454
Pubmed	p38alpha MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation.	MAPK14 POLR2A	1.41e-05	3	76	2	17468755
Pubmed	GABAC receptor sensitivity is modulated by interaction with MAP1B.	GABRR1 GABRR2	1.41e-05	3	76	2	11102469
Pubmed	Ferroportin and exocytoplasmic ferroxidase activity are required for brain microvascular endothelial cell iron efflux.	CP HEPH	1.41e-05	3	76	2	23640881
Pubmed	Promyelocytic leukemia is a direct inhibitor of SAPK2/p38 mitogen-activated protein kinase.	MAPK14 MAPK11	1.41e-05	3	76	2	15273249
Pubmed	Role of p38 mitogen-activated protein kinase isoforms in murine skin inflammation induced by 12-O-tetradecanoylphorbol 13-acetate.	MAPK14 MAPK11	1.41e-05	3	76	2	21336470
Pubmed	Fibronectin blocks p38 and jnk activation by cyclic strain in Caco-2 cells.	MAPK14 FN1	1.41e-05	3	76	2	12810082
Pubmed	p38 Mitogen-activated protein kinase and c-Jun NH2-terminal protein kinase regulate the accumulation of a tight junction protein, ZO-1, in cell-cell contacts in HaCaT cells.	MAPK14 TJP1	1.41e-05	3	76	2	25435485
Pubmed	[Ceruloplasmin, hephaestin and zyklopen: the three multicopper oxidases important for human iron metabolism].	CP HEPH	1.41e-05	3	76	2	24988611
Pubmed	Neither human hephaestin nor ceruloplasmin forms a stable complex with transferrin.	CP HEPH	1.41e-05	3	76	2	18022819
Pubmed	The p38 mitogen-activated protein kinase signaling pathway is involved in regulating low-density lipoprotein receptor-related protein 1-mediated β-amyloid protein internalization in mouse brain.	MAPK14 LRP1	1.41e-05	3	76	2	27163530
Pubmed	Protein arginine methyltransferase 1 interacts with and activates p38α to facilitate erythroid differentiation.	MAPK14 MAPK11	1.41e-05	3	76	2	23483889
Pubmed	Hematopoietic stem/progenitor cells directly contribute to arteriosclerotic progression via integrin β2.	LRP1 ITGB2	1.41e-05	3	76	2	25546260
Pubmed	Hepatocyte growth factor and p38 promote osteogenic differentiation of human mesenchymal stem cells.	MAPK14 MAPK11	1.41e-05	3	76	2	24673557
Pubmed	Severe Iron Metabolism Defects in Mice With Double Knockout of the Multicopper Ferroxidases Hephaestin and Ceruloplasmin.	CP HEPH	1.41e-05	3	76	2	30182051
Pubmed	Cloning and characterization of mouse GABA(C) receptor subunits.	GABRR1 GABRR2	1.41e-05	3	76	2	9507960
Pubmed	Comparative Phosphoproteomics Analysis of VEGF and Angiopoietin-1 Signaling Reveals ZO-1 as a Critical Regulator of Endothelial Cell Proliferation.	ANGPT1 TJP1	1.41e-05	3	76	2	26846344
Pubmed	Cholesterol depletion upregulates involucrin expression in epidermal keratinocytes through activation of p38.	MAPK14 MAPK11	1.41e-05	3	76	2	15304097
Pubmed	Iron promotes oxidative cell death caused by bisretinoids of retina.	CP HEPH	1.41e-05	3	76	2	29686088
Pubmed	Coxiella burnetii lipopolysaccharide blocks p38α-MAPK activation through the disruption of TLR-2 and TLR-4 association.	MAPK14 TLR2	1.41e-05	3	76	2	25610812
Pubmed	Genetic linkage and radiation hybrid mapping of the three human GABA(C) receptor rho subunit genes: GABRR1, GABRR2 and GABRR3.	GABRR1 GABRR2	1.41e-05	3	76	2	10542332
Pubmed	TLR2 affects CD86 expression and inflammatory response in burn injury mice through regulation of p38.	MAPK14 TLR2	1.41e-05	3	76	2	28460187
Pubmed	Molecular basis for the interaction of low density lipoprotein receptor-related protein 1 (LRP1) with integrin alphaMbeta2: identification of binding sites within alphaMbeta2 for LRP1.	LRP1 ITGB2	1.41e-05	3	76	2	21676865
Pubmed	The transcriptional activator Mirk/Dyrk1B is sequestered by p38alpha/beta MAP kinase.	MAPK14 MAPK11	1.41e-05	3	76	2	12384504
Pubmed	Candida albicans phospholipomannan triggers inflammatory responses of human keratinocytes through Toll-like receptor 2.	MAPK14 TLR2	1.41e-05	3	76	2	19196344
Pubmed	Chemical genetics define the roles of p38alpha and p38beta in acute and chronic inflammation.	MAPK14 MAPK11	1.41e-05	3	76	2	17855341
Pubmed	Lack of the T cell-specific alternative p38 activation pathway reduces autoimmunity and inflammation.	MAPK14 MAPK11	1.41e-05	3	76	2	21715315
Pubmed	Involvement of the p38 mitogen-activated protein kinase alpha, beta, and gamma isoforms in myogenic differentiation.	MAPK14 MAPK11	1.41e-05	3	76	2	18256287
Pubmed	Nerve growth factor inhibits apoptosis in memory B lymphocytes via inactivation of p38 MAPK, prevention of Bcl-2 phosphorylation, and cytochrome c release.	MAPK14 MAPK11	1.41e-05	3	76	2	11495898
Pubmed	GABAC receptors are functionally expressed in the intermediate zone and regulate radial migration in the embryonic mouse neocortex.	GABRR1 GABRR2	1.41e-05	3	76	2	20123002
Pubmed	Activin A induction of erythroid differentiation through MKK6-p38alpha/p38beta pathway is inhibited by follistatin.	MAPK14 MAPK11	1.41e-05	3	76	2	20162623
Pubmed	p38-dependent phosphorylation of the mRNA decay-promoting factor KSRP controls the stability of select myogenic transcripts.	MAPK14 MAPK11	1.41e-05	3	76	2	16364914
Pubmed	Phosphorylation of SNX27 by MAPK11/14 links cellular stress-signaling pathways with endocytic recycling.	MAPK14 MAPK11	1.41e-05	3	76	2	33605979
Pubmed	Conditional knockout of hephaestin in the neural retina disrupts retinal iron homeostasis.	CP HEPH	1.41e-05	3	76	2	35271829
Pubmed	Role of the JIP4 scaffold protein in the regulation of mitogen-activated protein kinase signaling pathways.	MAPK8IP1 MAPK14 MAPK11	1.50e-05	22	76	3	15767678
Pubmed	p38 and a p38-interacting protein are critical for downregulation of E-cadherin during mouse gastrulation.	MAPK14 FN1 MAPK11	1.50e-05	22	76	3	16751104
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	LIG4 HOXC13 GTF3C1 POLR2A SNX17 FBXW5 LRP1 ZFR SIN3A TOP2A	1.72e-05	857	76	10	25609649
Pubmed	Phosphorylation of c-Fos by members of the p38 MAPK family. Role in the AP-1 response to UV light.	MAPK14 MAPK11	2.82e-05	4	76	2	15708845
Pubmed	Bacterial fimbriae activate human peripheral blood monocytes utilizing TLR2, CD14 and CD11a/CD18 as cellular receptors.	TLR2 ITGB2	2.82e-05	4	76	2	12207338
Pubmed	Diaphanous-related formin mDia2 regulates beta2 integrins to control hematopoietic stem and progenitor cell engraftment.	DIAPH3 ITGB2	2.82e-05	4	76	2	32576838
Pubmed	ADAMTS18 regulates early branching morphogenesis of lacrimal gland and has a significant association with the risk of dry eye in mice.	FN1 TJP1	2.82e-05	4	76	2	35240198
Pubmed	Essential role for p38alpha MAPK but not p38gamma MAPK in Igf2 expression and myoblast differentiation.	MAPK14 MAPK11	2.82e-05	4	76	2	20610565
Pubmed	Developmentally regulated expression of GABA receptor rho1 and rho2 subunits, L7 and cone-rod homeobox (CRX) genes in mouse retina.	GABRR1 GABRR2	2.82e-05	4	76	2	11520487
Pubmed	Mice with hepcidin-resistant ferroportin accumulate iron in the retina.	CP HEPH	2.82e-05	4	76	2	26506980
Pubmed	Role for mitogen-activated protein kinase p38 alpha in lung epithelial branching morphogenesis.	MAPK14 MAPK11	2.82e-05	4	76	2	18177852
Pubmed	Targeting of p38 mitogen-activated protein kinases to MEF2 transcription factors.	MAPK14 MAPK11	2.82e-05	4	76	2	10330143
Interaction	WDR76 interactions	RAF1 NID2 GTF3C1 FN1 POLR2A SPTBN1 LRP1 ZFR EXOC2 DYNC1I2	1.33e-06	383	74	10	int:WDR76
Cytoband	9p24.2	SPATA6L KCNV2	1.47e-04	11	76	2	9p24.2
Cytoband	6q15	GABRR1 GABRR2	1.22e-03	31	76	2	6q15
Cytoband	Ensembl 112 genes in cytogenetic band chr3p14	MAGI1 CADPS KBTBD8	1.66e-03	140	76	3	chr3p14
Cytoband	12q13.3	HOXC13 LRP1	3.27e-03	51	76	2	12q13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr6q15	GABRR1 GABRR2	3.27e-03	51	76	2	chr6q15
GeneFamily	Dyneins, cytoplasmic	DYNC1I1 DYNC1I2	5.73e-04	13	50	2	538
GeneFamily	Mitogen-activated protein kinases	MAPK14 MAPK11	5.73e-04	13	50	2	651
GeneFamily	Gamma-aminobutyric acid type A receptor subunits	GABRR1 GABRR2	1.24e-03	19	50	2	563
GeneFamily	Calcium voltage-gated channel subunits\|Membrane associated guanylate kinases	MAGI1 TJP1	2.33e-03	26	50	2	904
CoexpressionAtlas	gamma delta T cells, Tgd.vg2-24ahi.Th, TCRd+ Vg2- CD24+, Thymus, avg-2	EPHB6 LIG4 EGLN3 GALNT10 ANGPT1 NUF2 DIAPH3 MAPK11 TOP2A	1.75e-05	422	75	9	GSM476658_500
ToppCell	PND01-03-samps-Mesenchymal-Matrix_fibroblast\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ANGPT1 GTF3C1 FN1 LRP1 CP ATP1A2	1.07e-06	196	76	6	54f4cf778f95a9ff662e5c7520916a25e605bf95
ToppCell	PND03-Immune-Immune_Myeloid-Granulocytic-Neutrophil-Neutrophil_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NID2 EGLN3 AEN ACRBP ITGB2	6.48e-06	153	76	5	489228ab81c3ae339a53a9da6c2a1c1b6ac3f84b
ToppCell	LPS-antiTNF-Lymphocytic_NKT-T_cells-Neutrophils\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	LIG4 GPATCH3 NUF2 MAPK11 TOP2A	6.48e-06	153	76	5	c4dcdcaa672929c1da870e9fb8ada1bb030ad12f
ToppCell	3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NUF2 DIAPH3 SVOP TOP2A ALOX12B	8.30e-06	161	76	5	2165897924c790fec43502283f1df221c56c1e9f
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell-NK_c01-FCGR3A\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AEN FN1 NECAB1 NUF2 TOP2A	1.21e-05	174	76	5	9bb8159a62640756d18ecbade3bf32bcbb7dd590
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AEN FN1 NECAB1 NUF2 TOP2A	1.21e-05	174	76	5	e70cc623a3a6aceec813ed852fec0c4240561133
ToppCell	saliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_ILC-NK_cell\|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)	AEN FN1 NECAB1 NUF2 TOP2A	1.21e-05	174	76	5	b6725086fe5a2b057c7c495ec63c970ac52c2580
ToppCell	Control-Epithelial_cells-AT1\|Control / group, cell type (main and fine annotations)	NEDD9 MAGI1 TJP1 SPTBN1 DIAPH3	1.21e-05	174	76	5	548d7f2b958a2bfd2c95eb049ceaab55a559c77d
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l20-1\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MAPK8IP1 NID2 FN1 LRP1 ADGRA1	1.21e-05	174	76	5	1d157f7a919c8246e83d8060d2a0017c6c781ef3
ToppCell	facs-Liver-Non-hepatocytes-3m-Lymphocytic-T_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	NUF2 DIAPH3 FAM199X DCK TOP2A	1.42e-05	180	76	5	87347af8f28cf7c486c19f3f98c0afb022c323b5
ToppCell	PND14-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	KBTBD8 NUF2 DIAPH3 DCK TOP2A	1.50e-05	182	76	5	21dcab170ffeef89faa9fee5008568cb6e15c694
ToppCell	facs-Lung-nan-3m-Mesenchymal-fibroblast_of_lung\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPT1 FN1 LRP1 CP ATP1A2	1.50e-05	182	76	5	c557de6ccd327c46e0a5423cd9936d78e0abae5f
ToppCell	facs-Lung-nan-3m-Mesenchymal-Alveolar_Fibroblast\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPT1 FN1 LRP1 CP ATP1A2	1.50e-05	182	76	5	dbe4b2557cf19e0682ed446f8397d3a1153642f0
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD9 MAGI1 TJP1 SPTBN1 DIAPH3	1.58e-05	184	76	5	57c792e6e2fedba25d3350ffe649fd74750b579d
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NEDD9 MAGI1 SPATA6L DIAPH3 TMC5	1.58e-05	184	76	5	29c95b814a0b1ad8734ed68b77df29c08594e5ec
ToppCell	nucseq-Epithelial-Epithelial_Alveolar-AT1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	NEDD9 MAGI1 TJP1 SPTBN1 DIAPH3	1.58e-05	184	76	5	d7bd0f0c607bade67c99e9fb3578a570298bf926
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MAGI1 TJP1 SPTBN1 DIAPH3 TMC5	1.62e-05	185	76	5	1c222f7285d6e3dae0354dc7e853ddc0ea55e63e
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CADPS SCN5A ADPRHL1 ATP1A2 DYNC1I1	1.62e-05	185	76	5	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CP NUF2 DIAPH3 TMC5 TOP2A	1.62e-05	185	76	5	4d0f3d86fab02c80093e62cb0c79c586c13c5412
ToppCell	droplet-Lung-LUNG-30m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 NID2 KLHL10 KCNV2 CP	1.67e-05	186	76	5	f23f21781a758541f59c06efa7739d26a03fb478
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FN1 ACRBP ESD LRP1 MTMR9	1.67e-05	186	76	5	38f9f7d3b782978fd23b2a7fe565266285d39e44
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	ELOA POLR2A KBTBD8 ERGIC2 CAMSAP2	1.67e-05	186	76	5	ed9b1a784f67e8a297e2a10993a6d97df60581ac
ToppCell	Epithelial-alveolar_epithelial_cell_type_1\|World / Lineage, Cell type, age group and donor	NEDD9 MAGI1 TJP1 DIAPH3 TMC5	1.67e-05	186	76	5	09d95daa3387a4814cffaa4b798cc2810c3759d0
ToppCell	droplet-Lung-LUNG-30m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 NID2 KLHL10 KCNV2 CP	1.67e-05	186	76	5	0de87109da9324c597fadf2eb782f0f158afe832
ToppCell	saliva-Mild-Moderate_progression_d12-25-Myeloid-Dendritic-conventional_dendritic_cell\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	FN1 ACRBP ESD LRP1 MTMR9	1.75e-05	188	76	5	e35104ca327c2d9eb6ffed658051f62f855a0a0e
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	NEDD9 FN1 NECAB1 SPTBN1 CP	1.80e-05	189	76	5	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	NEDD9 FN1 NECAB1 SPTBN1 CP	1.80e-05	189	76	5	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	facs-Lung-EPCAM-24m-Mesenchymal\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPT1 FN1 LRP1 CP ATP1A2	1.80e-05	189	76	5	324c81285c51f4f8bb1aef428b18fe2c549c2c11
ToppCell	Adult-Epithelial-alveolar_epithelial_cell_type_1-D231\|Adult / Lineage, Cell type, age group and donor	MAGI1 TJP1 SPTBN1 DIAPH3 TMC5	1.80e-05	189	76	5	5a04cb25f8f0447b2cecdb6c3695029281aca26d
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_1-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NEDD9 MAGI1 TJP1 SPTBN1 DIAPH3	1.85e-05	190	76	5	30b50d183d7649146eb1e79b47ba897355f1998a
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANGPT1 FN1 LRP1 CP ATP1A2	1.89e-05	191	76	5	094c9d3270fc1e487ccf10fb4936af5f081f6009
ToppCell	facs-Lung-24m-Mesenchymal\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANGPT1 FN1 LRP1 CP ATP1A2	1.89e-05	191	76	5	ba02cbdfda6a94374a6472eb88499059979af472
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANGPT1 FN1 LRP1 CP ATP1A2	1.89e-05	191	76	5	80484d39f34703a33b9bac09826b7a526e883cab
ToppCell	facs-Lung-24m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANGPT1 FN1 LRP1 CP ATP1A2	1.89e-05	191	76	5	5c4e4e9de14edfae072a2a2882220a31bebf51b2
ToppCell	facs-Lung-3m-Mesenchymal-fibroblast\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ANGPT1 FN1 LRP1 CP ATP1A2	1.89e-05	191	76	5	997abf0cc5873bed0372c4a333ed307fa72774d2
ToppCell	PND14-Mesenchymal-Mesenchymal_structural\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	1.94e-05	192	76	5	25492568f9cbe097b7bb1db50d8b817c80ea87d7
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	1.94e-05	192	76	5	de9c1536d5aee86f9c62acbc54ca8fa581c00f17
ToppCell	PND28-Mesenchymal-Mesenchymal_structural\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	1.99e-05	193	76	5	ec81c1afdae2e0433a22c8c1fa1c6232526ff7e7
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	1.99e-05	193	76	5	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	1.99e-05	193	76	5	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	TCGA-Endometrium-Primary_Tumor-Endometrial_Adenocarcinoma-Endometrioid-1\|TCGA-Endometrium / Sample_Type by Project: Shred V9	NLN AEN GALNT10 DIAPH3 DYNC1I1	1.99e-05	193	76	5	c2673d86f7d7b849788036032a93a6d136a70040
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	1.99e-05	193	76	5	30481fb01c7acf85beae10213f038da86bed6777
ToppCell	(3)_Chondrocytes-(33)_Chondro-prol/rest\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	NID2 NUF2 DIAPH3 TOP2A DYNC1I1	2.04e-05	194	76	5	c093c5e161b97ad770bfbaad3023eba4537101b5
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.3\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 NUF2 DIAPH3 DCK TOP2A	2.04e-05	194	76	5	e5b81a8e52259a54a911c1c2ac932c98c988318d
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	ANGPT1 FN1 LRP1 CP ATP1A2	2.04e-05	194	76	5	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	PND01-Mesenchymal-Mesenchymal_structural\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.09e-05	195	76	5	6bb6349d6ec8da094fe1c7c590021989337aeb0b
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.09e-05	195	76	5	3a0cad69cfc150a27a0666f612f5294c817197d7
ToppCell	PCW_10-12-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	ANGPT1 FN1 SPTBN1 LRP1 DYNC1I1	2.09e-05	195	76	5	1cdf5f296029ae424d9dba42e86a6d111e4896e6
ToppCell	PND14-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.09e-05	195	76	5	2b8ee7990267bb52b7e6ae03f509ffebf8908122
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.09e-05	195	76	5	a3b468125e48f072255cede7645f6692298ecf54
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-pulmonary_artery_endothelial_cell-EC_arterial-EC_arterial_L.2.4.1.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	NEDD9 EGLN3 TJP1 SPTBN1 SSTR1	2.14e-05	196	76	5	cf7f384c1771274e766bab03ecc3dfbd13f2df60
ToppCell	PND10-Mesenchymal\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.14e-05	196	76	5	ace167a40adb7022b365be3c2b1cbd4ba963739a
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.20e-05	197	76	5	06a0d7062dadda656decaf77dcef9a10b5f2698d
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature3_(17)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	ANGPT1 FN1 SPTBN1 LRP1 DYNC1I1	2.20e-05	197	76	5	31a1852911bda38543916585fda34255fd62a134
ToppCell	PND01-Mesenchymal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.20e-05	197	76	5	292b8cc3dafddf5d323fe4e3d3ea5ac61e6ce027
ToppCell	PND14-Mesenchymal\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.20e-05	197	76	5	9a14bc2e7d6081e2ab0e2e5555fc8804f13d3dbe
ToppCell	PND01-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	ANGPT1 FN1 LRP1 CP ATP1A2	2.20e-05	197	76	5	d35c7a36135b5ed6a7bf2f934849678eba2a0177
ToppCell	10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-SMC_COL-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	GABRR1 NID2 P4HA2 ANGPT1 FN1	2.25e-05	198	76	5	eb78b2ae6a787dbc75947e8dd5a03693285bc8be
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating-Alveolar_macrophage_proliferating_L.1.0.7.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 NUF2 DIAPH3 DCK TOP2A	2.30e-05	199	76	5	13ff6c26ebcc663ef8e5559ab9be99dab848abe7
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B-B_lineage\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	P4HA2 SPTBN1 NUF2 DCK TOP2A	2.30e-05	199	76	5	fe3b7d540a644dfc6beea171c809b4d1ba4e188f
ToppCell	LPS_IL1RA-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	NID2 ANGPT1 FN1 LRP1 CP	2.30e-05	199	76	5	a7dd94b172c973a131a6792f8ccd9bfe44d984ac
ToppCell	wk_15-18-Mesenchymal-Fibroblast-Alveolar_fibro\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	ANGPT1 FN1 SPTBN1 LRP1 DYNC1I1	2.30e-05	199	76	5	6bce8e65859a35cfea1c210f9c9765952d492ed2
ToppCell	10x3'2.3-week_12-13-Lymphocytic_B\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	P4HA2 SPTBN1 NUF2 DCK TOP2A	2.30e-05	199	76	5	cdee798e3586e4e7a15de598239090a85752ea1e
ToppCell	LPS_anti-TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ANGPT1 GTF3C1 FN1 SPTBN1 LRP1	2.36e-05	200	76	5	9b0916d8d07ac2bf1739f7be5296bf77ffee6094
ToppCell	3'-Parenchyma_lung-Immune_Myeloid-Myeloid_macrophage-alveolar_macrophage-Alveolar_macrophage_proliferating\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FN1 NUF2 DIAPH3 DCK TOP2A	2.36e-05	200	76	5	5e1b38e2aa8901bfb2623249f7b6302e97d56ace
ToppCell	Endothelial-H_(cycle)\|World / shred on cell class and cell subclass (v4)	NUF2 DIAPH3 TOP2A ALOX12B	7.94e-05	133	76	4	8e3005114761feee028c496cc739e607b35d7831
ToppCell	356C-Epithelial_cells-Epithelial-B_(AT2)\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NLN ANGPT1 TLR2 HEPH	9.42e-05	139	76	4	aefcfda2b2db302ce4b3d2a09f767be0b1c3ac6c
ToppCell	356C-Epithelial_cells-Epithelial-B_(AT2)-\|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)	NLN ANGPT1 TLR2 HEPH	9.42e-05	139	76	4	b9c2dfab119ac0efdf931bb2910e82bccdb4e48d
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c13-MKI67-CCL5_l\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	MAPK8IP1 NUF2 MAPK11 TOP2A	1.20e-04	148	76	4	6cd7ef4f29d9a0944f724d9d8117d4d25e517fe4
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Vip-Vip_Lmo1_Fam159b\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	EGLN3 ANGPT1 SCN5A CP	1.23e-04	149	76	4	98ae408d2d0347865875ff8bbd89d359decea526
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Connecting_Tubule_Intercalated_Cell_Type_A\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MAGI1 GALNT10 ANGPT1 PLCG2	1.26e-04	150	76	4	87968ce885a4959616f0321f58517fe8029ba1b1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SCN5A DIAPH3 TOP2A C13orf42	1.47e-04	156	76	4	955547dfeb1b1ad4957b4338701055726b22619f
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL10 KBTBD8 ATP1A2 SVOP	1.54e-04	158	76	4	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL10 KBTBD8 ATP1A2 SVOP	1.54e-04	158	76	4	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Enterocyte_(Proximal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLHL10 FN1 TMEM43 ITGB2	1.58e-04	159	76	4	709b57f992a29878cc899d760d144d36cb5cb280
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 EGLN3 CP TMC5	1.70e-04	162	76	4	3a1cbfed5a063131d49e3c1584f62b12660ecb36
ToppCell	facs-Pancreas-Endocrine-3m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI1 EGLN3 CP TMC5	1.70e-04	162	76	4	04b3c38bb27fa369a9ac5b60883f8b058abc5180
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	MAGI1 CP BTBD9 TMC5	1.70e-04	162	76	4	5c9bc3c3857a99d8a3caf359a7eb279ce9cc1c81
ToppCell	facs-BAT-Fat-3m-Myeloid-myeloid_cell\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLR2 TMEM43 DCK ITGB2	1.82e-04	165	76	4	bfe330751d34813af7540765b490406078c40da7
ToppCell	Ionocyte\|World / shred by cell class for turbinate	ADGRA1 PLCG2 SSTR1 ALOX12B	1.82e-04	165	76	4	0cb2199b87f17ece743fb2652b2f448dfa78ae0b
ToppCell	390C-Myeloid-Dendritic-cDC_proliferating_2\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	SPATA6L NUF2 DIAPH3 TOP2A	1.82e-04	165	76	4	a5c3af634d2698f9a01cf074791756b7669f9fff
ToppCell	facs-BAT-Fat-3m-Myeloid\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TLR2 TMEM43 DCK ITGB2	1.82e-04	165	76	4	8bdeacbb47948fabae2575689f811a9fad47f779
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 TLR2 PLCG2 ITGB2	1.86e-04	166	76	4	82fa07632f7e586698fbf37381715b40f9f6ae3a
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 TLR2 PLCG2 ITGB2	1.86e-04	166	76	4	bf6c35c3e67ef4ca98a38926c6f7923ecca0508a
ToppCell	facs-Lung-EPCAM-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 TLR2 PLCG2 ITGB2	1.86e-04	166	76	4	433128b7d964b32faa0bf437a02facc819ab1405
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 TLR2 PLCG2 ITGB2	1.86e-04	166	76	4	0d03926452414f232c77fd15d5f48d148f9fca3b
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Krt73-Inhibitory_Gad1Gad2_Htr3a.Krt73_(Interneuron,__(candidate_CGE-derived_8))-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GABRR1 EGLN3 C13orf42	1.88e-04	65	76	3	a3aac8aada31451c33165257773daaae676ad04e
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Krt73\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GABRR1 EGLN3 C13orf42	1.88e-04	65	76	3	02e778b500f62e5fb70e2f7d493a0280980e6a24
ToppCell	Hippocampus-Neuronal-Inhibitory-iN2(Gad1Gad2)-Krt73-Inhibitory_Gad1Gad2_Htr3a.Krt73_(Interneuron,__(candidate_CGE-derived_8))\|Hippocampus / BrainAtlas - Mouse McCarroll V32	GABRR1 EGLN3 C13orf42	1.88e-04	65	76	3	af69f27937e6c55ae937f16c418ff267c3ba6a8a
ToppCell	Adult-Mesenchymal-vascular_smooth_muscle_cell-D175\|Adult / Lineage, Cell type, age group and donor	GABRR2 CADPS HEPH DYNC1I1	1.91e-04	167	76	4	c4e321bb87512ea839f324c92c0f1afea891483f
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 TLR2 PLCG2 ITGB2	1.95e-04	168	76	4	0ffad93ba2fb5d4cfda2c13011059555475dcfc8
ToppCell	facs-Lung-18m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l2\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FN1 TLR2 PLCG2 ITGB2	1.95e-04	168	76	4	ab1fb9b2cc7c5853b7fbd373e1784a9a31f96d38
ToppCell	Dividing_Macrophages-Donor_08\|World / lung cells shred on cell class, cell subclass, sample id	KLHL10 NUF2 DIAPH3 TOP2A	2.00e-04	169	76	4	eb0c993ef2eea73bc4881182520922ce9ae9368f
ToppCell	facs-Lung-nan-3m-Myeloid-Classical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 PLCG2 DCK ITGB2	2.00e-04	169	76	4	05b138511039f1255a5f647040b1b9bdf222bd52
ToppCell	PND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	FN1 NUF2 DIAPH3 TOP2A	2.00e-04	169	76	4	563c267edaade0e5df192ad953801ef9768d4270
ToppCell	facs-Lung-nan-3m-Myeloid-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FN1 PLCG2 DCK ITGB2	2.00e-04	169	76	4	bf0a97f53d6e3f9ffeaeae0402b010c49a6cccb7
ToppCell	Dividing_Macrophages-IPF_04\|World / lung cells shred on cell class, cell subclass, sample id	FN1 NUF2 DCK TOP2A	2.00e-04	169	76	4	bc859a103cad567caf50c3c3882d2d2017807c73
ToppCell	droplet-Spleen-nan-21m-Hematologic-proerythroblast\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANGPT1 FN1 LRP1 HEPH	2.04e-04	170	76	4	03cb4e508356f85372a588c8d1c6babf2a012683
ToppCell	PND10-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_G2M\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA1 NID2 ITGB2 TOP2A	2.04e-04	170	76	4	7534ac69ca3a378df78d61c284e89bc96a71a4a8
ToppCell	5'-Parenchyma_lung-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.4.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MAPK14 NUF2 DIAPH3 TOP2A	2.04e-04	170	76	4	cf22a843ae2d9cd6693507fed2b7c6a45abea10e
Drug	compound 9b	RAF1 MAPK14 MAPK11 DCK	4.79e-07	20	74	4	CID000207510
Drug	AC1L1KMJ	NEDD9 RAF1 MAPK14 FN1 TJP1 SPTBN1 TLR2 PLCG2 MAPK11 ITGB2	3.15e-06	476	74	10	CID000030956
Drug	AC1L1JGQ	RAF1 MAPK14 TLR2 PLCG2 MAPK11	4.00e-06	73	74	5	CID000005034
Drug	chloroquine	EPHB6 MAPK14 FN1 ELMOD2 TLR2 LRP1 MAPK11 ITGB2	4.35e-06	288	74	8	CID000002719
Drug	Phenylephrine	RAF1 MAPK8IP1 NID2 EGLN3 MAPK14 ANGPT1 FN1 CADPS TMEM43 ADPRHL1	5.31e-06	505	74	10	ctd:D010656
Drug	nemorosone	RAF1 MAPK14 MAPK11	5.34e-06	11	74	3	CID000637105
Drug	Fe(III	ATRN P4HA2 EGLN3 MAPK14 IPO8 CP PLCG2 MAPK11 ALOX12B HEPH	9.09e-06	537	74	10	CID000023925
Drug	indiganylidynestibane	CP HEPH	1.04e-05	2	74	2	CID003468413
Drug	deferoxamine	EPHB6 P4HA2 MAPK14 FN1 CP MAPK11 HEPH DYNC1I1	1.55e-05	343	74	8	CID000002973
Drug	SB 239063	RAF1 MAPK14 MAPK11	1.79e-05	16	74	3	CID000005166
Drug	AGEPC	GABRR1 GABRR2 MAPK14 FN1 PLCG2 MAPK11 ITGB2 ALOX12B	2.03e-05	356	74	8	CID000461545
Drug	4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3,4-d)pyrimidine	RAF1 MAPK14 ATP1A2 ITGB2	2.47e-05	52	74	4	ctd:C108123
Drug	P-38	EPHB6 RAF1 MAPK8IP1 MAPK14 ANGPT1 FN1 TLR2 FBXW5 PLCG2 MAPK11	2.84e-05	613	74	10	CID000200878
Drug	trapidil	EPHB6 RAF1 MAPK14 MAPK11	3.56e-05	57	74	4	CID000005531
Drug	Indapamide [26807-65-8]; Down 200; 10.6uM; PC3; HT_HG-U133A	NEDD9 NID2 EGLN3 IPO8 SPTBN1 TLR2	4.17e-05	195	74	6	3778_DN
Drug	BW-B 70C; Down 200; 31.6uM; MCF7; HT_HG-U133A_EA	MAPK14 HOXC13 TJP1 ZFR DCK CAMSAP2	4.17e-05	195	74	6	1132_DN
Drug	Esculin Hydrate [531-75-9]; Up 200; 11.8uM; PC3; HT_HG-U133A	GABRR2 LIG4 MAPK14 ANGPT1 IPO8 SPTBN1	4.42e-05	197	74	6	6310_UP
Drug	Clioquinol	ATRN P4HA2 FN1 TOP2A	4.97e-05	62	74	4	ctd:D007464
Drug	tyrphostin B46	MAPK14 PLCG2 MAPK11	5.57e-05	23	74	3	CID000002058
Drug	AC1L1DKK	RAF1 MAPK14 PLCG2 MAPK11 DCK	5.91e-05	127	74	5	CID000002390
Drug	AC1L1JM9	RAF1 MAPK14 FN1 TLR2 PLCG2 MAPK11 ITGB2	5.91e-05	304	74	7	CID000005103
Drug	Ac2-26	MAPK14 MAPK11	6.23e-05	4	74	2	CID000568638
Drug	AC1L2ZKY	RAF1 FN1	6.23e-05	4	74	2	CID000131675
Drug	NSC-68458	MAPK14 MAPK11	6.23e-05	4	74	2	CID000249771
Drug	Hypertensin II	RAF1 EGLN3 MAPK14 ANGPT1 FN1 SCN5A LRP1 MAPK11	7.57e-05	429	74	8	CID000025476
Drug	AC1Q5V5T	MAPK14 ANGPT1 FN1 ZFR MAPK11	7.89e-05	135	74	5	CID000004701
Drug	R59949	RAF1 P4HA2 MAPK14 MAPK11	8.01e-05	70	74	4	CID000657356
Drug	AC1L1G9T	NEDD9 RAF1 MAPK14 FN1 PLCG2 MAPK11 ITGB2 ALOX12B	8.07e-05	433	74	8	CID000003591
Drug	AC1NSK9Q	RAF1 MAPK14 MAPK11	8.12e-05	26	74	3	CID005311233
Drug	histamine	EPHB6 RAF1 MAPK14 TJP1 TLR2 PLCG2 MAPK11 ITGB2 ALOX12B	8.24e-05	560	74	9	CID000000774
Drug	AC1NDZBN	RAF1 PLCG2 MAPK11	9.11e-05	27	74	3	CID004634037
Drug	H2O2	RAF1 LIG4 P4HA2 EGLN3 MAPK14 FN1 TJP1 CP PLCG2 ATP1A2 MAPK11 ITGB2 ALOX12B	1.02e-04	1183	74	13	CID000000784
Drug	okadaic acid tetramethyl ether	RAF1 FN1	1.04e-04	5	74	2	CID000147507
Drug	norisoguaiacin	LIG4 ESD	1.04e-04	5	74	2	CID000170835
Drug	Simvastatin	RAF1 MAPK14 ANGPT1 FN1 SNX17 TLR2 LRP1 PLCG2 ITGB2	1.09e-04	581	74	9	ctd:D019821
Drug	NM 108	MAGI1 TLR2 DCK	1.13e-04	29	74	3	CID000500901
Drug	Ac-dmqd-cho	RAF1 TLR2 MAPK11	1.26e-04	30	74	3	CID011421257
Drug	arachidonic acid trifluoromethyl ketone	RAF1 MAPK14 PLCG2 MAPK11 ALOX12B	1.42e-04	153	74	5	CID000002224
Drug	Methamphetamine	MAGI1 P4HA2 SPATA6L FN1 ACRBP NECAB1 TLR2 SCN5A LRP1 NUF2 DIAPH3 MAPK11 SPTY2D1 TOP2A	1.47e-04	1401	74	14	ctd:D008694
Drug	tolyltriazole	MAPK14 MAPK11	1.55e-04	6	74	2	CID000025902
Drug	pentacarboxyporphyrin	EPHB6 CP	1.55e-04	6	74	2	CID000168756
Disease	Cardiomyopathies	RAF1 MAPK14 TLR2 SCN5A TMEM43 MAPK11	9.44e-07	130	74	6	C0878544
Disease	Microcephaly	LIG4 SIN3A ATP1A2 DYNC1I2	2.48e-05	67	74	4	C0025958
Disease	intraocular pressure measurement	P4HA2 EGLN3 EFHC1 ANGPT1 SPTBN1 KBTBD8 ADPRHL1 EXOC2	4.12e-05	509	74	8	EFO_0004695
Disease	Waldenstrom macroglobulinemia	SYNE3 EXOC2	6.17e-05	5	74	2	EFO_0009441
Disease	QRS-T angle	ANGPT1 SPTBN1 SCN5A ADPRHL1	1.49e-04	106	74	4	EFO_0020097
Disease	N-acetylcarnosine measurement	GABRR1 GABRR2	1.72e-04	8	74	2	EFO_0022101
Disease	AUTISM, SUSCEPTIBILITY TO, 15	POLR2A SIN3A	1.72e-04	8	74	2	C2677504
Disease	developmental disorder of mental health (implicated_via_orthology)	GABRR1 GABRR2 SIN3A	2.57e-04	49	74	3	DOID:0060037 (implicated_via_orthology)
Disease	cortical thickness	MAGI1 P4HA2 EGLN3 ANGPT1 KIAA0825 CADPS SPTBN1 LRP1 DIAPH3 EXOC2	4.50e-04	1113	74	10	EFO_0004840
Disease	Malignant neoplasm of liver	RAF1 EGLN3 MAPK14 TOP2A	4.56e-04	142	74	4	C0345904
Disease	Liver neoplasms	RAF1 EGLN3 MAPK14 TOP2A	4.56e-04	142	74	4	C0023903
Disease	Migraine Disorders	LRP1 ATP1A2	4.75e-04	13	74	2	C0149931
Disease	Cardiomyopathies, Primary	MAPK14 TLR2 MAPK11	7.04e-04	69	74	3	C0033141
Disease	Myocardial Diseases, Secondary	MAPK14 TLR2 MAPK11	7.04e-04	69	74	3	C0036529
Disease	cardiomyopathy (implicated_via_orthology)	RAF1 LEMD2 LRP1	7.66e-04	71	74	3	DOID:0050700 (implicated_via_orthology)
Disease	perinatal necrotizing enterocolitis (biomarker_via_orthology)	TJP1 TLR2	8.24e-04	17	74	2	DOID:8677 (biomarker_via_orthology)
Disease	spinal stenosis	ELMOD2 DYNC1I1	8.24e-04	17	74	2	EFO_0007490
Disease	anthropometric measurement	P4HA2 FN1 POLR2A DYNC1I1	8.55e-04	168	74	4	EFO_0004302
Disease	age-related hearing impairment	MAGI1 NID2 EGLN3 SPTBN1 DYNC1I1	1.34e-03	324	74	5	EFO_0005782
Disease	colorectal health	NEDD9 LIG4 ANGPT1 DIAPH3	1.66e-03	201	74	4	EFO_0008460
Disease	Adenocarcinoma of lung (disorder)	RAF1 MAPK14 TOP2A ALOX12B	1.81e-03	206	74	4	C0152013
Disease	Antiglaucoma preparations and miotics use measurement	ANGPT1 EXOC2	1.94e-03	26	74	2	EFO_0009944
Disease	Encephalopathies	CP ATP1A2	2.09e-03	27	74	2	C0085584
Disease	brain ischemia (biomarker_via_orthology)	TJP1 SCN5A CP	2.18e-03	102	74	3	DOID:2316 (biomarker_via_orthology)
Disease	cardiovascular age measurement	SPTBN1 SCN5A	2.41e-03	29	74	2	EFO_0803380
Disease	Strabismus	CADPS EXOC2	2.41e-03	29	74	2	HP_0000486

Protein segments in the cluster

Peptide	Gene	Start	Entry
DSSTDMEQYMEDQYW	AEN	291	Q8WTP8
YVDATEDPWKTNYRM	ESD	106	P10768
WFEEEPESIMYFNLY	ELMOD2	256	Q8IZ81
SERSWMDDYDYVHLQ	NEDD9	621	Q14511
DEMNEIYDENSYWRN	ACRBP	296	Q8NEB7
EFSVYQDTWMKYEYE	ERGIC2	51	Q96RQ1
RNYGTEDEDTAYCWM	ADGRA1	156	Q86SQ6
LYYLRQEEDRAWMYS	C13orf42	66	A0A1B0GVH6
ELMDWEGNRAYSQYD	ANGPT1	376	Q15389
RAELDEAYDVYNMVW	DIAPH3	411	Q9NSV4
YAMTVWYFDAEERAE	EGLN3	206	Q9H6Z9
RDSSYYWEIEASEVM	RAF1	336	P04049
ERTYYIAAVEVEWDY	CP	731	P00450
EMYIERLFDQWYNSS	CADPS	1251	Q9ULU8
QSEDEADYYCMIWPS	IGLV5-37	106	A0A075B6J1
DEEMTGYVATRWYRA	MAPK11	176	Q15759
WEMAYTENGEVYFID	MAGI1	306	Q96QZ7
VSYMEEEQLWDFLYN	KIAA0825	871	Q8IV33
YVDWEQDMERYPYVG	LEMD2	426	Q8NC56
WNRSSKYLDEAYEEM	MTMR9	501	Q96QG7
AEDYWYEAYNMRTGA	MAPK8IP1	521	Q9UQF2
DDEMTGYVATRWYRA	MAPK14	176	Q16539
VWMDEYAEYIYQRRP	GALNT10	396	Q86SR1
DYDDNYDYLESGNWM	PHKA1	631	P46020
ALDFDYREQMIYWTD	LRP1	3061	Q07954
ADDLYRYDVDTQMWT	ATRN	531	O75882
YSFEDNADYVYDVMW	DYNC1I1	526	O14576
EDNADYVYDVMWSPT	DYNC1I2	521	Q13409
WSAMTNDEQVEYIEY	FAM199X	181	Q6PEV8
TADDWDVDMSVYYDR	GPATCH3	356	Q96I76
AMSWYEEFQRLYDTV	FBXW5	66	Q969U6
VWVDEMNYYDMRTDR	EXOC2	106	Q96KP1
REACRETYMEFLWQY	NUF2	131	Q9BZD4
RMRYAVYWDELASEV	DDHD2	96	O94830
WYYDSLSRGEAEDML	PLCG2	646	P16885
YDDIADQWMKVYETP	KBTBD8	561	Q8NFY9
DEWDSPHIVRYYDVM	P4HA2	331	O15460
GIDYDCRERMVYWTD	NID2	1146	Q14112
WVAYTLEQQDGMDRY	ITGB2	671	P05107
TMNDLEDSYGQEWTY	ATP1A2	891	P50993
IESYAYTEDDLMLYW	GABRR1	216	P24046
TDEWYDAHDMSIYRS	KLHL10	551	Q6JEL2
EMASLIADLEYRYSW	LIG4	791	P49917
PEEYESWREMYLRLQ	ELOA	646	Q14241
YTVSHYAVGDEWERM	FN1	2301	P02751
TDYWCLDDLYREMVR	ADPRHL1	71	Q8NDY3
AYQWMDGYETLALRE	ALOX12B	101	O75342
WPESLMYVYEDSAAE	HOXC13	11	P31276
YAIWDDTDSMYGECR	EFHC1	246	Q5JVL4
LYESECMNETEWTIY	DCK	141	P27707
SYSYFIEVSMDELDW	BTBD9	346	Q96Q07
TDLPYDIEDAVMYWI	CAMSAP2	171	Q08AD1
LESYAYTDEDLMLYW	GABRR2	196	P28476
EELWQEDPYEYIRMK	IPO8	366	O15397
SWMDNAAEEPVDYYA	SSTR1	341	P30872
MWDELAYYEENTRDF	SPATA6L	76	Q8N4H0
EYLSEEDYMDLLWTT	SVOP	366	Q8N4V2
MYQWVETEESREYTE	TMEM43	121	Q9BTV4
TSDELEDLRYQWMLY	SYNE3	871	Q6ZMZ3
SYGERPYWDMSEQEV	EPHB6	856	O15197
AARIYYIMAEEVEWD	HEPH	731	Q9BQS7
YIMAEEVEWDYCPDR	HEPH	736	Q9BQS7
WTEGNYNYYIEEDED	KCNV2	46	Q8TDN2
WMDIMYAAVDSRGYE	SCN5A	1421	Q14524
ERWSDYVERYMNSDT	SIN3A	1096	Q96ST3
KDESDYALRYMESSW	SPTY2D1	631	Q68D10
QYYFDAAEAEAWMSE	SPTBN1	1596	Q01082
INAWDLYYYMTQTEE	NLN	356	Q9BYT8
LRKSYWDSAYDDDVM	SNX17	201	Q15036
VAEDQEWVNVYYEMP	POLR2A	1186	P24928
EWVNVYYEMPDFDVA	POLR2A	1191	P24928
EDRVPMYEEQWSYYD	TJP1	1081	Q07157
MWVYDEDVGINYREV	TOP2A	61	P11388
RYEEDMYWRRMEEEQ	ZFR	661	Q96KR1
MSAYYRNNWSEEDPD	TMC5	1	Q6UXY8
ETVYVDDASWMRYIP	GTF3C1	876	Q12789
SYSERDAYWVENLMV	TLR2	646	O60603
ESRYMIYEFWENSSV	NECAB1	296	Q8N987