Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP hydrolysis activity	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP RAD50	3.38e-05	441	42	7	GO:0016887
GeneOntologyMolecularFunction	ATP-dependent activity	MCM3 LONP1 SETX ATAD2 BCS1L ATAD2B VCP RAD50	3.58e-05	614	42	8	GO:0140657
GeneOntologyMolecularFunction	DNA helicase activity	MCM3 SETX RAD50	3.00e-04	62	42	3	GO:0003678
GeneOntologyMolecularFunction	G-quadruplex DNA binding	LONP1 RAD50	3.87e-04	14	42	2	GO:0051880
GeneOntologyMolecularFunction	ribonucleoside triphosphate phosphatase activity	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP RAD50	1.06e-03	775	42	7	GO:0017111
GeneOntologyMolecularFunction	pyrophosphatase activity	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP RAD50	1.68e-03	839	42	7	GO:0016462
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP RAD50	1.69e-03	840	42	7	GO:0016817
GeneOntologyMolecularFunction	hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP RAD50	1.69e-03	840	42	7	GO:0016818
GeneOntologyMolecularFunction	catalytic activity, acting on DNA	MCM3 SETX POLE2 RAD50	2.19e-03	262	42	4	GO:0140097
GeneOntologyMolecularFunction	ATP-dependent activity, acting on DNA	MCM3 SETX RAD50	2.41e-03	127	42	3	GO:0008094
GeneOntologyMolecularFunction	single-stranded DNA binding	MCM3 LONP1 RAD50	2.80e-03	134	42	3	GO:0003697
GeneOntologyMolecularFunction	helicase activity	MCM3 SETX RAD50	4.45e-03	158	42	3	GO:0004386
GeneOntologyMolecularFunction	ADP binding	LONP1 VCP	4.58e-03	48	42	2	GO:0043531
GeneOntologyBiologicalProcess	regulation of complement activation	SUSD4 C6 SVEP1	2.22e-05	27	42	3	GO:0030449
GeneOntologyBiologicalProcess	complement activation, classical pathway	SUSD4 C6 SVEP1	9.81e-05	44	42	3	GO:0006958
GeneOntologyBiologicalProcess	negative regulation of complement activation, classical pathway	SUSD4 SVEP1	1.12e-04	8	42	2	GO:0045959
GeneOntologyBiologicalProcess	regulation of complement activation, classical pathway	SUSD4 SVEP1	1.80e-04	10	42	2	GO:0030450
GeneOntologyBiologicalProcess	regulation of humoral immune response	SUSD4 C6 SVEP1	2.48e-04	60	42	3	GO:0002920
GeneOntologyBiologicalProcess	negative regulation of humoral immune response mediated by circulating immunoglobulin	SUSD4 SVEP1	2.64e-04	12	42	2	GO:0002924
GeneOntologyBiologicalProcess	humoral immune response mediated by circulating immunoglobulin	SUSD4 C6 SVEP1	2.73e-04	62	42	3	GO:0002455
GeneOntologyBiologicalProcess	protein-containing complex disassembly	SETX MAP1A ATAD2 ATAD2B VCP	3.00e-04	291	42	5	GO:0032984
GeneOntologyBiologicalProcess	negative regulation of complement activation	SUSD4 SVEP1	3.63e-04	14	42	2	GO:0045916
GeneOntologyBiologicalProcess	complement activation	SUSD4 C6 SVEP1	3.91e-04	70	42	3	GO:0006956
GeneOntologyBiologicalProcess	DNA replication	MCM3 WEE1 MCIDAS POLE2 RAD50	4.12e-04	312	42	5	GO:0006260
GeneOntologyBiologicalProcess	regulation of DNA-templated DNA replication initiation	MCM3 MCIDAS	4.18e-04	15	42	2	GO:0030174
GeneOntologyBiologicalProcess	DNA-templated DNA replication	MCM3 MCIDAS POLE2 RAD50	4.65e-04	178	42	4	GO:0006261
GeneOntologyBiologicalProcess	negative regulation of immunoglobulin mediated immune response	SUSD4 SVEP1	4.77e-04	16	42	2	GO:0002890
GeneOntologyBiologicalProcess	negative regulation of B cell mediated immunity	SUSD4 SVEP1	4.77e-04	16	42	2	GO:0002713
GeneOntologyBiologicalProcess	DNA duplex unwinding	MCM3 SETX RAD50	5.37e-04	78	42	3	GO:0032508
GeneOntologyBiologicalProcess	negative regulation of humoral immune response	SUSD4 SVEP1	6.77e-04	19	42	2	GO:0002921
GeneOntologyBiologicalProcess	DNA geometric change	MCM3 SETX RAD50	7.14e-04	86	42	3	GO:0032392
GeneOntologyBiologicalProcess	nucleosome disassembly	ATAD2 ATAD2B	9.11e-04	22	42	2	GO:0006337
GeneOntologyBiologicalProcess	regulation of humoral immune response mediated by circulating immunoglobulin	SUSD4 SVEP1	9.11e-04	22	42	2	GO:0002923
GeneOntologyBiologicalProcess	DNA conformation change	MCM3 SETX RAD50	9.25e-04	94	42	3	GO:0071103
Domain	AAA	LONP1 ATAD2 BCS1L ATAD2B VCP	9.54e-08	52	41	5	PF00004
Domain	ATPase_AAA_core	LONP1 ATAD2 BCS1L ATAD2B VCP	1.16e-07	54	41	5	IPR003959
Domain	ATPase_AAA_CS	ATAD2 BCS1L ATAD2B VCP	4.56e-07	29	41	4	IPR003960
Domain	AAA+_ATPase	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP	6.81e-07	144	41	6	IPR003593
Domain	AAA	MCM3 LONP1 ATAD2 BCS1L ATAD2B VCP	6.81e-07	144	41	6	SM00382
Domain	AAA	ATAD2 BCS1L ATAD2B VCP	8.84e-07	34	41	4	PS00674
Domain	MACPF_2	MPEG1 C6	9.81e-05	7	41	2	PS51412
Domain	MACPF_1	MPEG1 C6	9.81e-05	7	41	2	PS00279
Domain	TB	LTBP1 FBN3	9.81e-05	7	41	2	PF00683
Domain	-	LTBP1 FBN3	1.31e-04	8	41	2	3.90.290.10
Domain	EGF_3	LTBP1 C6 FBN3 SVEP1 CNTNAP1	1.57e-04	235	41	5	PS50026
Domain	EGF	LTBP1 FBN3 SVEP1 CNTNAP1	1.65e-04	126	41	4	PF00008
Domain	TB	LTBP1 FBN3	1.68e-04	9	41	2	PS51364
Domain	TB_dom	LTBP1 FBN3	1.68e-04	9	41	2	IPR017878
Domain	-	MCM3 LONP1 SETX ATAD2 BCS1L ATAD2B VCP RAD50	1.85e-04	746	41	8	3.40.50.300
Domain	Sushi	SUSD4 C6 SVEP1	2.01e-04	52	41	3	PF00084
Domain	EGF-like_dom	LTBP1 C6 FBN3 SVEP1 CNTNAP1	2.05e-04	249	41	5	IPR000742
Domain	CCP	SUSD4 C6 SVEP1	2.25e-04	54	41	3	SM00032
Domain	EGF_1	LTBP1 C6 FBN3 SVEP1 CNTNAP1	2.29e-04	255	41	5	PS00022
Domain	SUSHI	SUSD4 C6 SVEP1	2.51e-04	56	41	3	PS50923
Domain	EGF-like_CS	LTBP1 C6 FBN3 SVEP1 CNTNAP1	2.55e-04	261	41	5	IPR013032
Domain	MACPF	MPEG1 C6	2.55e-04	11	41	2	PF01823
Domain	Sushi_SCR_CCP_dom	SUSD4 C6 SVEP1	2.65e-04	57	41	3	IPR000436
Domain	EGF_2	LTBP1 C6 FBN3 SVEP1 CNTNAP1	2.73e-04	265	41	5	PS01186
Domain	MACPF	MPEG1 C6	3.06e-04	12	41	2	SM00457
Domain	MACPF	MPEG1 C6	3.06e-04	12	41	2	IPR020864
Domain	P-loop_NTPase	MCM3 LONP1 SETX ATAD2 BCS1L ATAD2B VCP RAD50	4.40e-04	848	41	8	IPR027417
Domain	EGF_CA	LTBP1 FBN3 SVEP1	8.85e-04	86	41	3	PF07645
Domain	EGF_Ca-bd_CS	LTBP1 FBN3 SVEP1	1.25e-03	97	41	3	IPR018097
Domain	EGF_CA	LTBP1 FBN3 SVEP1	1.33e-03	99	41	3	PS01187
Domain	ASX_HYDROXYL	LTBP1 FBN3 SVEP1	1.37e-03	100	41	3	PS00010
Domain	cEGF	LTBP1 FBN3	1.48e-03	26	41	2	IPR026823
Domain	cEGF	LTBP1 FBN3	1.48e-03	26	41	2	PF12662
Domain	EGF-type_Asp/Asn_hydroxyl_site	LTBP1 FBN3 SVEP1	1.62e-03	106	41	3	IPR000152
Domain	hEGF	FBN3 SVEP1	1.71e-03	28	41	2	PF12661
Domain	EGF	LTBP1 FBN3 SVEP1 CNTNAP1	1.72e-03	235	41	4	SM00181
Domain	EGF_CA	LTBP1 FBN3 SVEP1	2.42e-03	122	41	3	SM00179
Domain	EGF-like_Ca-bd_dom	LTBP1 FBN3 SVEP1	2.53e-03	124	41	3	IPR001881
Domain	Kazal_2	C6 FSTL5	2.83e-03	36	41	2	PF07648
Domain	BROMODOMAIN_1	ATAD2 ATAD2B	2.98e-03	37	41	2	PS00633
Domain	Bromodomain	ATAD2 ATAD2B	3.14e-03	38	41	2	PF00439
Domain	BROMODOMAIN_2	ATAD2 ATAD2B	3.65e-03	41	41	2	PS50014
Domain	BROMO	ATAD2 ATAD2B	3.83e-03	42	41	2	SM00297
Domain	Bromodomain	ATAD2 ATAD2B	3.83e-03	42	41	2	IPR001487
Domain	-	ATAD2 ATAD2B	3.83e-03	42	41	2	1.20.920.10
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	DECR1 MCM3 FLNC LONP1 LTBP1 ZNF143 GALNT1 BCS1L VCP AXIN1 CNTNAP1	8.33e-07	1451	42	11	30550785
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNC LONP1 SRRM2 ATAD2 ZC3H13 ATAD2B VCP RAD50	9.95e-07	653	42	8	22586326
Pubmed	p97/VCP inhibition causes excessive MRE11-dependent DNA end resection promoting cell killing after ionizing radiation.	VCP RAD50	8.53e-06	4	42	2	34038735
Pubmed	TNIP2 is a Hub Protein in the NF-κB Network with Both Protein and RNA Mediated Interactions.	DECR1 MCM3 SRRM2 WEE1 ZC3H13 VCP ZNF746 AXIN1	1.26e-05	922	42	8	27609421
Pubmed	SPRTN protease-cleaved MRE11 decreases DNA repair and radiosensitises cancer cells.	VCP RAD50	1.42e-05	5	42	2	33558481
Pubmed	Identification of DeltaNp63alpha protein interactions by mass spectrometry.	FLNC MAP1A VCP	2.73e-05	48	42	3	20085233
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	DECR1 MCM3 FLNC LONP1 SETX SRRM2 ATAD2 VCP RAD50	2.78e-05	1353	42	9	29467282
Pubmed	Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex.	DECR1 MCM3 FLNC LONP1 SRRM2 VCP AXIN1	4.77e-05	809	42	7	32129710
Pubmed	Chemical Crosslinking Mass Spectrometry Analysis of Protein Conformations and Supercomplexes in Heart Tissue.	DECR1 FSIP2 LONP1 BCS1L ZC3H13	4.83e-05	331	42	5	29199018
Pubmed	Cancer-associated FBXW7 loss is synthetic lethal with pharmacological targeting of CDC7.	LONP1 WEE1 POLE2 VCP	5.97e-05	175	42	4	37866880
Pubmed	Comparative architectural aspects of regions of conserved synteny on human chromosome 11p15.3 and mouse chromosome 7 (including genes WEE1 and LMO1).	ZNF143 WEE1	6.37e-05	10	42	2	11528126
Pubmed	Multiple UBX proteins reduce the ubiquitin threshold of the mammalian p97-UFD1-NPL4 unfoldase.	MCM3 VCP	6.37e-05	10	42	2	35920641
Pubmed	Comprehensive proteomic analysis of interphase and mitotic 14-3-3-binding proteins.	MCM3 WEE1 ZC3H13 VCP	8.21e-05	190	42	4	15161933
Pubmed	Destabilization of Atoh1 by E3 Ubiquitin Ligase Huwe1 and Casein Kinase 1 Is Essential for Normal Sensory Hair Cell Development.	FLNC MAP1A SRRM2	1.08e-04	76	42	3	27542412
Pubmed	Spatiotemporal-resolved protein networks profiling with photoactivation dependent proximity labeling.	FSIP2 MCM3 FLNC SRRM2 ZC3H13	1.16e-04	399	42	5	35987950
Pubmed	p62-Dependent Phase Separation of Patient-Derived KEAP1 Mutations and NRF2.	MCM3 VCP	1.48e-04	15	42	2	30126895
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	SRRM2 VCP RAD50	1.51e-04	85	42	3	16051665
Pubmed	Comparative genomic sequencing reveals a strikingly similar architecture of a conserved syntenic region on human chromosome 11p15.3 (including gene ST5) and mouse chromosome 7.	ZNF143 WEE1	1.69e-04	16	42	2	11528127
Pubmed	Proteome analysis of the circadian clock protein PERIOD2.	MCM3 FLNC VCP	2.03e-04	94	42	3	35122331
Pubmed	DNA replication in eukaryotic cells.	MCM3 POLE2	2.15e-04	18	42	2	12045100
Pubmed	Proteomic analysis identifies dysfunction in cellular transport, energy, and protein metabolism in different brain regions of atypical frontotemporal lobar degeneration.	DECR1 VCP CNTNAP1	2.23e-04	97	42	3	22360420
Pubmed	Centrosome-related genes, genetic variation, and risk of breast cancer.	MCM3 WEE1 VCP	2.59e-04	102	42	3	20508983
Pubmed	PINK1 Content in Mitochondria is Regulated by ER-Associated Degradation.	MCM3 FLNC SRRM2 ZC3H13 VCP	2.66e-04	477	42	5	31300519
Pubmed	Methyltransferase-like 21e inhibits 26S proteasome activity to facilitate hypertrophy of type IIb myofibers.	FLNC LTBP1 SETX VCP	2.69e-04	259	42	4	31162944
Pubmed	The p97/VCP segregase is essential for arsenic-induced degradation of PML and PML-RARA.	LONP1 SETX VCP RAD50	2.81e-04	262	42	4	36880596
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	MCM3 FLNC SETX MAP1A SRRM2 ZC3H13 VCP	2.88e-04	1082	42	7	38697112
Pubmed	A multiprotein complex necessary for both transcription and DNA replication at the β-globin locus.	MCM3 RAD50	2.95e-04	21	42	2	20808282
Pubmed	Ubiquilin 2 modulates ALS/FTD-linked FUS-RNA complex dynamics and stress granule formation.	MCM3 ATAD2 VCP RAD50	3.11e-04	269	42	4	30442662
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	MCM3 SRRM2 ATAD2 WEE1 ZC3H13 RAD50	3.16e-04	774	42	6	15302935
Pubmed	Host E3 ligase HUWE1 attenuates the proapoptotic activity of the MERS-CoV accessory protein ORF3 by promoting its ubiquitin-dependent degradation.	LONP1 MAP1A BCAS3 VCP RAD50	4.46e-04	534	42	5	35032548
Pubmed	Mutations of the Transcriptional Corepressor ZMYM2 Cause Syndromic Urinary Tract Malformations.	SETX ZNF746 RAD50	4.70e-04	125	42	3	32891193
Pubmed	ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage.	VCP RAD50	4.90e-04	27	42	2	17525332
Pubmed	TRAIP regulates replication fork recovery and progression via PCNA.	MCM3 RAD50	4.90e-04	27	42	2	27462463
Pubmed	Substrate trapping proteomics reveals targets of the βTrCP2/FBXW11 ubiquitin ligase.	FLNC WEE1 AXIN1	5.03e-04	128	42	3	25332235
Pubmed	Arginine methylation and ubiquitylation crosstalk controls DNA end-resection and homologous recombination repair.	MCM3 FLNC ZC3H13 VCP RAD50	5.14e-04	551	42	5	34728620
Pubmed	The STUbL RNF4 regulates protein group SUMOylation by targeting the SUMO conjugation machinery.	FLNC ZNF143 METAP1D SRRM2 VCP AXIN1 CNTNAP1	5.44e-04	1203	42	7	29180619
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	MCM3 SRRM2 WEE1 VCP	5.77e-04	317	42	4	17620599
Pubmed	Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.	MCM3 SETX MAP1A WEE1 RAD50	6.89e-04	588	42	5	38580884
Pubmed	Amyotrophic Lateral Sclerosis Overview	SETX VCP	7.34e-04	33	42	2	20301623
Pubmed	Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin.	MCM3 LTBP1 SRRM2	7.83e-04	149	42	3	26370502
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	MAP1A SRRM2 BCAS3 CNTNAP1	8.08e-04	347	42	4	17114649
Pubmed	SPATA2-Mediated Binding of CYLD to HOIP Enables CYLD Recruitment to Signaling Complexes.	FLNC LTBP1 SRRM2 VCP	8.61e-04	353	42	4	27545878
Pubmed	BAG5 Promotes Alpha-Synuclein Oligomer Formation and Functionally Interacts With the Autophagy Adaptor Protein p62.	MCM3 MAP1A VCP	8.94e-04	156	42	3	32850835
Pubmed	The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.	MCM3 ZNF143 SETX SRRM2 ZC3H13 ATAD2B	9.47e-04	954	42	6	36373674
Pubmed	A bead-based approach for large-scale identification of in vitro kinase substrates.	MCM3 SRRM2 ZC3H13	1.01e-03	163	42	3	22113938
Pubmed	Proteomic characterization of chromosomal common fragile site (CFS)-associated proteins uncovers ATRX as a regulator of CFS stability.	MCM3 SRRM2 ATAD2 VCP RAD50	1.09e-03	652	42	5	31180492
Pubmed	MYC multimers shield stalled replication forks from RNA polymerase.	MCM3 FLNC SRRM2 ATAD2 VCP RAD50	1.14e-03	989	42	6	36424410
Pubmed	A neurogenomics approach to gene expression analysis in the developing brain.	SUSD4 GALNT1 FSTL5	1.15e-03	170	42	3	15582152
Cytoband	8q21.3	DECR1 CYP7B1	3.27e-04	29	42	2	8q21.3
GeneFamily	AAA ATPases	LONP1 ATAD2 BCS1L ATAD2B VCP	1.67e-08	53	28	5	413
GeneFamily	Hyalectan proteoglycans\|V-set domain containing\|Sushi domain containing\|C-type lectin domain containing	SUSD4 C6 SVEP1	9.20e-05	57	28	3	1179
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l44-58\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FLNC SUSD4 ZNF143 WEE1	1.92e-05	169	42	4	d382a76d85875663502cc7dde2e3e0682605768e
ToppCell	IIF-Lymphocyte-T_NK-T_NK_proliferative\|IIF / Disease, Lineage and Cell Type	MCM3 ATAD2 POLE2 ETV7	2.68e-05	184	42	4	ab8b45ce40e8c5f66e5c23332a591b4f9cba4ce1
ToppCell	facs-Thymus-Flowthrough-3m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM3 ATAD2 WEE1 POLE2	3.17e-05	192	42	4	e8d47504b744040a762ec9b670a66cc060b2ae86
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MCM3 ATAD2 POLE2 VCP	3.30e-05	194	42	4	17af04acd54dd6a895a966cbb4422de25dc4f1e6
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte-female\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MCM3 ATAD2 POLE2 VCP	3.30e-05	194	42	4	3c385d93c5fe1a7817813c492f79fdb94d887357
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic-lymphocyte\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	MCM3 ATAD2 POLE2 VCP	3.30e-05	194	42	4	635d0e88f9c542a1d9363066c6cdbc6e44db76c1
ToppCell	control-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MCM3 ATAD2 WEE1 POLE2	3.37e-05	195	42	4	bfaceb0601cf3855f38d6e1f482f01ad03ef11fe
ToppCell	mild-Lymphocytic-Prol._cells\|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MCM3 ATAD2 WEE1 POLE2	3.37e-05	195	42	4	9a8cc9097a349fd0a53ccf2723ee8bb1418d6aca
ToppCell	PCW_05-06-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	MCM3 XYLB ATAD2 POLE2	3.37e-05	195	42	4	56d8734d020b3da08a5aa9e67999706a9e023a99
ToppCell	PCW_07-8.5-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	MCM3 XYLB ATAD2 POLE2	3.37e-05	195	42	4	b65463a804fed2d9a3be9e528ca8b9c98469bc86
ToppCell	Healthy-T/NK_proliferative\|Healthy / disease group, cell group and cell class	MCM3 ATAD2 WEE1 POLE2	3.43e-05	196	42	4	91e44aabb2e85dcc77ddae6f7e000118d45d1de6
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_cycling-mes_proliferating1_(3)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	MCM3 XYLB ATAD2 POLE2	3.43e-05	196	42	4	df366d76ea55f49e349d622effa57c1535df8400
ToppCell	Healthy-T/NK_proliferative\|World / disease group, cell group and cell class	MCM3 ATAD2 WEE1 POLE2	3.50e-05	197	42	4	e90be1e7e02f736b6aab14010a912b592d6f1e80
ToppCell	mild-Myeloid-Immature_Neutrophils_2\|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	MCM3 ATAD2 WEE1 POLE2	3.50e-05	197	42	4	bd9d57e0c873f6526dca322f4dad8e6bd692586c
ToppCell	(00)_Basal-(2)_GFP_FOXI1\|(00)_Basal / shred by cell type by condition	SETX GALNT1 ZC3H13 RAD50	3.64e-05	199	42	4	19674e1eaeb51e4196d847cb62aa437c852951d3
ToppCell	(09)_Interm._secr.>cil.-(2)_GFP_FOXI1\|(09)_Interm._secr.>cil. / shred by cell type by condition	SETX GALNT1 ZC3H13 RAD50	3.64e-05	199	42	4	fc680f85ebd3bab4c72876a19a461b0afb5f51ce
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells-Neuroepithelial_cell\|10w / Sample Type, Dataset, Time_group, and Cell type.	MCM3 LTBP1 ATAD2 WEE1	3.72e-05	200	42	4	8f8b8c225cdc79baf16fe04be89bdb65e404a055
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-10w-Stem_cells\|10w / Sample Type, Dataset, Time_group, and Cell type.	MCM3 LTBP1 ATAD2 WEE1	3.72e-05	200	42	4	a1f48eca9efb4f3ec3c9ace20f8c9257dd72c4ed
ToppCell	MS-IIF-Lymphocyte-T/NK-T/NK_proliferative\|IIF / Disease, condition lineage and cell class	MCM3 ATAD2 POLE2 ETV7	3.72e-05	200	42	4	c7c1806a1054b2b034a26a18aac93fc3bec4dbc8
ToppCell	(3)_MNP-(3)_DC_Monocyte_Dividing\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	MCM3 ATAD2 WEE1 POLE2	3.72e-05	200	42	4	d94fe9bd6ee7c1fed14666f24de41bda014e299b
ToppCell	mild-T/NK_proliferative\|mild / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MCM3 ATAD2 WEE1 POLE2	3.72e-05	200	42	4	25b4a1a33348e274bd4457efc0d6faa5421c3d31
ToppCell	mild-T/NK_proliferative\|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class	MCM3 ATAD2 WEE1 POLE2	3.72e-05	200	42	4	63cc57b9331459efbb73051d174d198a3568b938
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 FLNC MAP1A	2.97e-04	138	42	3	c1a46fbf1beffa12c3d1b78361e0613e2e9e2d13
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 FLNC MAP1A	3.23e-04	142	42	3	67d4ff3483ae34f77c3325aa0fbd3462ca19ade4
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM3 ATAD2 WEE1	3.50e-04	146	42	3	2d907e50206c4762a8baa741363bc7f0a04bd84e
ToppCell	E18.5-samps-Mesenchymal-Pericyte-pericyte_D\|E18.5-samps / Age Group, Lineage, Cell class and subclass	FLNC LTBP1 XYLB	3.72e-04	149	42	3	dcf68eb25733b5db2893728fe4dca5c7267eb58c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TDRD5 FLNC MAP1A	3.79e-04	150	42	3	afd651c654e715414eff64cf3a37378d057a56a2
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPEG1 MCM3 ATAD2	4.33e-04	157	42	3	eea53cf8d8a607264e1ee00b7a97c94bcf2ac80d
ToppCell	E18.5-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPEG1 MCM3 ATAD2	4.41e-04	158	42	3	f61ebe3a316e4259387cd9da83707f15e6473cae
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_Tubular-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	MCM3 SRRM2 LIPH	4.49e-04	159	42	3	655c0749c238bd68cb797adb83e25a23b8a3cc9d
ToppCell	3'-Airway_Nasal-Immune_Myeloid-Myeloid_monocytic-classical_monocyte-Classical_monocytes-Classical_monocytes_L.1.2.0.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	MPEG1 XYLB MCIDAS	4.66e-04	161	42	3	3a5f2877e3b29463a3a6da05009b0ab8747b4c47
ToppCell	343B-Myeloid-Dendritic-cDC1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	DECR1 MPEG1 LIPH	4.66e-04	161	42	3	537a1d86de99a493b0345ca0f760994260e97049
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	MYBPHL MAP1A LIPH	4.66e-04	161	42	3	bfb79277889142133ce86492a808f3083a7547e8
ToppCell	droplet-Thymus-nan-21m-Myeloid-Macrophage\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 C6 MYBPHL	4.66e-04	161	42	3	441ebd3c029861d833fbcf8a68fc740d9de8ef2f
ToppCell	PBMC-Mild-Hematopoietic-Platelet-Platelet-plt_2\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MYBPHL MAP1A LIPH	4.66e-04	161	42	3	d6f4b0e4e3b2a4e6232a6de3d67b210e24f8c89d
ToppCell	Brain_organoid-organoid_Velasco_nature-3_mon-Neuronal-Cajal-Retzius\|3_mon / Sample Type, Dataset, Time_group, and Cell type.	SUSD4 SVEP1 FSTL5	4.75e-04	162	42	3	1f589a763f3fd4e1e612809ef3903879d47dc1d8
ToppCell	facs-Lung-3m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TMEM150B MPEG1 AXIN1	4.83e-04	163	42	3	f558ad9569e5137e62a601ba4f073e69ed8f8650
ToppCell	PND28-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_T-CD8_T-CD8_T_prolif\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM3 ATAD2 POLE2	4.92e-04	164	42	3	5621c2e3fae84d5a2e4f1595e454bcb3a2b3f93c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SUSD4 MCIDAS FSTL5	5.01e-04	165	42	3	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	SUSD4 MCIDAS FSTL5	5.01e-04	165	42	3	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	droplet-Skin-nan-18m-Epithelial-stem_cell_of_epidermis\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XYLB ATAD2 POLE2	5.01e-04	165	42	3	96f0d8bc9b13e23f757e6bb98cd7dc061a8a9564
ToppCell	droplet-Spleen-nan-3m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150B MPEG1 MYBPHL	5.09e-04	166	42	3	c1f18de4a1a2b6cdc703e6d29d136e1134fcbdf3
ToppCell	droplet-Spleen-nan-3m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150B MPEG1 MYBPHL	5.09e-04	166	42	3	94c30d6ca179d0cb02a5ed0093c5a2871e17ae50
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-4M-Stem_cells-neuroepithelial-like_cells\|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.	FSTL5 ZNF746 CNTNAP1	5.18e-04	167	42	3	e488d9c7cf4355959e3833de3bd496c13fc11b1b
ToppCell	390C-Lymphocytic-CD4_T-cell-Treg_cell_4\|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)	CYP7B1 LTBP1 ETV7	5.27e-04	168	42	3	63437b3c3a66f953eaed600965ab193f9cc49da2
ToppCell	367C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	LTBP1 ZNF143 SMIM10L1	5.27e-04	168	42	3	80233a13135fd159f5764336a1fe67fba237776b
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	MCM3 ATAD2 POLE2	5.37e-04	169	42	3	121768fc51fc3441ec725346a1bbe29e21d05971
ToppCell	PND10-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_ILC-NK-ILC-ILC_prolif\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM3 GALNT1 ATAD2	5.37e-04	169	42	3	20fbf78382fb0ba9a63ab1aa0abc615476994ac5
ToppCell	droplet-Spleen-nan-3m-Myeloid-macrophage\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150B MPEG1 MYBPHL	5.55e-04	171	42	3	5b74df72e36ad04dfb25c72f1ca8efe043f6cda6
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	METAP1D SVEP1 FSTL5	5.55e-04	171	42	3	a5634b76476b8b2488a706bbab5141f7bd94631f
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	MPEG1 MAP1A CNTNAP1	5.55e-04	171	42	3	1f8e66073088fc1969782e443bf00f8c1877ea91
ToppCell	droplet-Spleen-nan-18m-Myeloid-nan\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 CYP7B1 MYBPHL	5.65e-04	172	42	3	850e4c9e9003807c19695be4b13121b0808a9389
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-thrombocytic\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LTBP1 MAP1A LIPH	5.65e-04	172	42	3	1a9b99c7fc297d9e4b6098bf0c4fb98927a05f6d
ToppCell	10x_3'_v3-spleen_(10x_3'_v3)-hematologic-thrombocytic-platelet\|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	LTBP1 MAP1A LIPH	5.65e-04	172	42	3	d588ca825ab301910c1378e009b766c809b0bd5e
ToppCell	droplet-Spleen-nan-18m-Myeloid\|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MPEG1 CYP7B1 MYBPHL	5.65e-04	172	42	3	018d8160cfcb7882475620dc678f48a69a0f643e
ToppCell	10x5'-Lung-Lymphocytic_NK-Cycling_NK\|Lung / Manually curated celltypes from each tissue	MCM3 ATAD2 LIPH	5.74e-04	173	42	3	d815832f89f70662706620e3b03ebb1dabec0034
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM3 ATAD2 POLE2	5.74e-04	173	42	3	5c55e1e27e9e3e77600d378cc87b51cc73907527
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC-EPC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MCM3 ATAD2 POLE2	5.84e-04	174	42	3	66555c610251ea04f968c258e312d720c18e7cde
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	MPEG1 ATAD2 POLE2	5.84e-04	174	42	3	a75ba49ccea6bd3d78ada1092b46deb5202c58a5
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-6_VIP_VIP\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	METAP1D FBN3 SVEP1	5.94e-04	175	42	3	e78bf0c33a741bb97e987e41ac33da9e623a08ec
ToppCell	PBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c12-MKI67-TYROBP\|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCM3 ATAD2 POLE2	5.94e-04	175	42	3	86dfce849b2ec023a72f7e887fa681b117155e51
ToppCell	droplet-Liver-Hepatocytes-21m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TMEM150B MPEG1 C6	6.04e-04	176	42	3	8e89471f838ea81235256cc2470f1c12c9b75f8a
ToppCell	PND03-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MPEG1 MCM3 ATAD2	6.04e-04	176	42	3	270d7908dbd84028958d257f94941dc685e20255
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	CYP7B1 LTBP1 SVEP1	6.14e-04	177	42	3	cdfd2f0ee2f692271b1525e414b0f645cdadb1f6
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYP7B1 LTBP1 METAP1D	6.14e-04	177	42	3	e55d21d4d61a069b9bbe0e7595fbfb7cfbacfd87
ToppCell	356C-Fibroblasts-Fibroblast-C_(Myofibroblast)\|356C / Donor, Lineage, Cell class and subclass (all cells)	CYP7B1 LTBP1 SVEP1	6.14e-04	177	42	3	db222faaecbe5600da39277243c4e7e764eb63c9
ToppCell	343B-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|343B / Donor, Lineage, Cell class and subclass (all cells)	CYP7B1 LTBP1 METAP1D	6.14e-04	177	42	3	43ba6f12c2fb32698a420bf799d46ac1b558f146
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-mature_enterocytic-Enterocyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	C6 MYBPHL LIPH	6.14e-04	177	42	3	1f5b6498364b2017c4d49cd337d6e91c8e4f840d
ToppCell	metastatic_Brain-Fibroblasts-Undetermined\|metastatic_Brain / Location, Cell class and cell subclass	LTBP1 XYLB MAP1A	6.14e-04	177	42	3	54f39be5d90363cfd44dea1a96ae06d3143aa795
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	METAP1D FBN3 SVEP1	6.24e-04	178	42	3	3c973aac16988e88f5677d3d695dd772ccfd6570
ToppCell	facs-Limb_Muscle-Muscle_Diaphragm-18m-Lymphocytic-T_cell\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MCM3 BCS1L POLE2	6.24e-04	178	42	3	5ac5257d88fa0dc67714881d6f005f6cea925710
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	LTBP1 MAP1A LIPH	6.24e-04	178	42	3	850fcd368c4478c57eaedc74544773ea220f41f3
ToppCell	PBMC-Convalescent-Hematopoietic-Platelet-Platelet-plt_3\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	LTBP1 MAP1A LIPH	6.24e-04	178	42	3	a16857da9f2907c176213a326112a1b4cbd0e628
ToppCell	Pericytes-Donor_05\|World / lung cells shred on cell class, cell subclass, sample id	FLNC LTBP1 MAP1A	6.24e-04	178	42	3	a2448d868da2abe48c394c51264aad03e866dfec
ToppCell	3'_v3-blood-Hematopoietic_Erythro-Mega-Megakaryocyte_early\|blood / Manually curated celltypes from each tissue	LTBP1 MAP1A LIPH	6.34e-04	179	42	3	290772eece76d70555dca8b8d82bd88b47e2fc35
ToppCell	PND07-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SUSD4 C6 ATAD2	6.34e-04	179	42	3	bf012825e88626e59cd1deebf67c2cd269ce4829
ToppCell	LPS-IL1RA-Endothelial-Endothelial-FOXM1\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	MCM3 WEE1 POLE2	6.45e-04	180	42	3	334e2b1f6eb7d4ece20b1c7b02107863f913237f
ToppCell	Influenza_Severe-Platelet\|World / Disease group and Cell class	LTBP1 MAP1A LIPH	6.55e-04	181	42	3	5cdf935a89440114a58fa2042c1daed740d91c00
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d03-09-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c11-MKI67-FOS\|Severe-critical_progression_d03-09 / Compartment, severity and other cell annotations on 10x 3' data (130k)	MCM3 MAP1A POLE2	6.55e-04	181	42	3	6873c1138b28c130637d06b64981ad11c262e85f
ToppCell	Influenza_Severe-Platelet\|Influenza_Severe / Disease group and Cell class	LTBP1 MAP1A LIPH	6.55e-04	181	42	3	4d037b098bb6f780ed8b15c0ec23a6f4d86bf45a
ToppCell	Healthy_Control-Lymphoid-T-\|Healthy_Control / Condition, Lineage, Cell class and cell subclass	CYP7B1 ATAD2 WEE1	6.55e-04	181	42	3	ac1ee313910c05b1b3cb497bae14565464919c21
ToppCell	5'-Adult-LymphNode-Mesenchymal-fibroblastic-Transitional_Stromal_3_(C3+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CYP7B1 C6 SVEP1	6.55e-04	181	42	3	ab66a89f316b935d9ba1277426d976b1e9e39757
ToppCell	PBMC-Control-cDC_12\|Control / Compartment, Disease Groups and Clusters	MCM3 ATAD2 POLE2	6.66e-04	182	42	3	4774066d0f9986abc3d13a2a3bc99ce4f1327ae0
ToppCell	10x5'-Liver-Lymphocytic_T_CD4/8-lo-Cycling_T\|Liver / Manually curated celltypes from each tissue	MCM3 ATAD2 POLE2	6.66e-04	182	42	3	81557cdc88777f3bd4e1dd18a760b08fc29122ef
ToppCell	metastatic_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	MPEG1 MAP1A CNTNAP1	6.66e-04	182	42	3	02e04294fce12591c32d7bd0e866a000ad1f836e
ToppCell	3'_v3-blood-Hematopoietic_Erythro-Mega\|blood / Manually curated celltypes from each tissue	LTBP1 MAP1A LIPH	6.66e-04	182	42	3	3100165c5ba8c3016f9a2f7a8e4ea136750823fe
ToppCell	PND01-Immune-Immune_Myeloid-Monocytic-Macrophage-AM-AM_prolif\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TMEM150B MPEG1 ATAD2	6.66e-04	182	42	3	57f8b8d7b132f3ad6f2b1e79c3812fe938657d2c
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	METAP1D FBN3 FSTL5	6.66e-04	182	42	3	420a8fd30543e37a66ba0786215d056d308660d0
ToppCell	P28-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	LTBP1 SVEP1 RAD50	6.66e-04	182	42	3	19c5e3a9d9b3728303b682102e276adfe93aa759
ToppCell	severe_influenza-Platelet\|severe_influenza / disease group, cell group and cell class (v2)	LTBP1 MAP1A LIPH	6.66e-04	182	42	3	2018b71ec26bf3cd7ecdc04d5473900a697cd58a
ToppCell	HSPCs-Mono_prog.\|World / Lineage and Cell class	TMEM150B MPEG1 MCM3	6.76e-04	183	42	3	1b73070baa9e5d5ada4ce25a77741630af9c1a3a
ToppCell	wk_20-22-Epithelial-Proximal_epithelial-Late_airway_progenitor\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SUSD4 LIPH FBN3	6.76e-04	183	42	3	0cea883a8a79fc58abcb26b08bf5db9d3d60f7d4
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	METAP1D FBN3 SVEP1	6.87e-04	184	42	3	32473dbdb2de66391157c5814ef34e790806e4f2
ToppCell	control-Others\|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	LTBP1 MAP1A LIPH	6.87e-04	184	42	3	a63b39fcc570b554cf10e8e47c2c1e079034768f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	METAP1D FBN3 SVEP1	6.98e-04	185	42	3	cefd81adb480c027545a5c78dcd05669783717f4
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-OPC-like-OPC-like-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MAP1A ATAD2 VCP	7.09e-04	186	42	3	10565fce7e1b4ec88bc8e1ed6410a83800be5014
ToppCell	(2)_Fibroblasts-(20)_Fibro-1\|(2)_Fibroblasts / Cell class and subclass of bone marrow stroma cells in homeostatis	FLNC LTBP1 SVEP1	7.09e-04	186	42	3	e93415b59dd89bc8a966dab0e0b65fe215933598
ToppCell	(0)_MSCs-(00)_Lepr-MSC\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	LTBP1 C6 SVEP1	7.09e-04	186	42	3	f0d156167d7cc2cd8a76e5a364233e9f2170bc01
ToppCell	(0)_MSCs\|World / Cell class and subclass of bone marrow stroma cells in homeostatis	LTBP1 C6 SVEP1	7.09e-04	186	42	3	a832c1e0035bcd559722eccf262c145deb3494c7
ToppCell	severe-Others\|severe / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs	LTBP1 MAP1A LIPH	7.09e-04	186	42	3	234a4bc7c3529daf8804f2a366887d02a47075cd
Disease	Lipid Metabolism, Inborn Errors	DECR1 CYP7B1	2.82e-05	6	41	2	C0023772
Disease	Amyotrophic lateral sclerosis	SETX VCP	2.53e-04	17	41	2	cv:C0002736
Disease	response to angiotensin receptor blocker	BCAS3 FSTL5	7.99e-04	30	41	2	EFO_0010735
Disease	cutaneous squamous cell carcinoma	ZNF143 WEE1	9.68e-04	33	41	2	EFO_1001927

Protein segments in the cluster

Peptide	Gene	Start	Entry
GSYSTGFPVAKPCFS	TDRD5	226	Q8NAT2
TYRRKFSPIGGTGPS	ATG4A	56	Q8WYN0
IRTGTSYFFGGCPKP	CNTNAP1	476	P78357
YLLYGPPGCGKSSFI	BCS1L	226	Q9Y276
CINPGSFPRSGFSFK	POLE2	496	P56282
RGCLFYGPPGTGKTL	ATAD2	461	Q6PL18
YGAIEKGSCARPFPG	FBN3	621	Q75N90
ITKRTGPYLFGAGCF	BCAS3	541	Q9H6U6
GPYLFGAGCFSIKAP	BCAS3	546	Q9H6U6
YICTGDFPPGTKGNT	RAD50	51	Q92878
YCVKSGLFTGGSLPP	MPEG1	576	Q2M385
PLGYGGFPKSVCTSV	METAP1D	141	Q6UB28
SKPCCYIFPGGRGDS	MAP1A	36	P78559
GCLFYGPPGTGKTLV	ATAD2B	436	Q9ULI0
PTKYTYCPGIVSGGF	FSIP2	3586	Q5CZC0
GSYRCTCKIGFGPDP	LTBP1	646	Q14766
NGDGTFRCSYVPTKP	FLNC	721	Q14315
RGSTQGKILCFYGPP	LONP1	511	P36776
FYGPPGVGKTSIARS	LONP1	521	P36776
PGCPKTILGGFQYFK	LIPH	231	Q8WWY8
KFFPGCTGGSPVSVY	MCIDAS	46	D6RGH6
TGANFKFYPPGCRVT	METTL7A	81	Q9H8H3
YFIGCKPDSTGAVSP	FSTL5	661	Q8N475
YRCLPGKKGGYTSGT	MCM3	241	P25205
PCGLAPRRFFSYGTK	DECR1	16	Q16698
FRKATPYTFPGGTGQ	GALNT1	346	Q10472
VCGPFFGGIFRLKTP	ETV7	121	Q9Y603
TCPKGFVVAGPSRYT	C6	731	P13671
DPRPASYSFCSGKGV	AXIN1	36	O15169
RKPGPFDGGIYTCKA	MYBPHL	321	A2RUH7
PFGTGTSKCPGRFFA	CYP7B1	441	O75881
CAGVKSSTPPGESYF	SRRM2	1036	Q9UQ35
SKGFPYISICGSFPP	TMEM150B	36	A6NC51
GCKVPFGESKYFPSS	SETX	1671	Q7Z333
SPAATPTSYGVFCKG	SMIM10L1	16	P0DMW3
SCPLGTYQPKFGSRS	SVEP1	1071	Q4LDE5
LACPFYGTTPFAGSR	SVEP1	1141	Q4LDE5
PYFLGSSFSPVRCGG	WEE1	131	P30291
PFKCPFEGCGRSFTT	ZNF143	326	P52747
GGPTSSIPILCSYFF	RBP3	1086	P10745
SKGVLFYGPPGCGKT	VCP	511	P55072
PVGTVISYRCFPGFK	SUSD4	201	Q5VX71
YGFPPGCKVVAFTGD	XYLB	266	O75191
FNEPCKYPGRTKGFG	ZNF746	421	Q6NUN9
TCRFVHGPSPRGKGY	ZC3H13	56	Q5T200
FRAKTTPECGPTGYV	JTB	66	O76095