Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	ATP-dependent activity	ATP13A4 TRAP1 MYH14 MYO10 SUPV3L1 CFTR KIF14 MACF1 ASCC3 DNAH5 DHX29 DNAH1	1.56e-05	614	88	12	GO:0140657
GeneOntologyMolecularFunction	serpin family protein binding	CTSL CTSV	1.92e-05	2	88	2	GO:0097655
GeneOntologyMolecularFunction	cysteine-type carboxypeptidase activity	CTSL CTSV	1.15e-04	4	88	2	GO:0016807
GeneOntologyMolecularFunction	ATP hydrolysis activity	ATP13A4 TRAP1 SUPV3L1 CFTR KIF14 MACF1 ASCC3 DNAH5 DHX29	1.41e-04	441	88	9	GO:0016887
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYH14 MYO10 KIF14 DNAH5 DNAH1	1.75e-04	118	88	5	GO:0003774
GeneOntologyMolecularFunction	kininogen binding	CTSL CTSV	1.90e-04	5	88	2	GO:0030984
GeneOntologyMolecularFunction	actin filament binding	SPTBN5 MYH14 MYO10 SPTB SPTBN2 MACF1	5.04e-04	227	88	6	GO:0051015
GeneOntologyMolecularFunction	dynein intermediate chain binding	SPTBN5 DNAH5 DNAH1	5.77e-04	37	88	3	GO:0045505
GeneOntologyMolecularFunction	cysteine-type exopeptidase activity	CTSL CTSV	8.44e-04	10	88	2	GO:0070004
GeneOntologyMolecularFunction	histone binding	L3MBTL2 SBNO1 BAZ1B MPHOSPH8 CTSL CTSV	1.13e-03	265	88	6	GO:0042393
GeneOntologyMolecularFunction	actin binding	SPTBN5 MYH14 MYO10 SPTB SPTBN2 MACF1 UTRN SLC4A1	1.24e-03	479	88	8	GO:0003779
GeneOntologyMolecularFunction	phosphatidylinositol-3,4,5-trisphosphate binding	GBF1 MYO10 ARAP1	1.32e-03	49	88	3	GO:0005547
GeneOntologyBiologicalProcess	epithelial cilium movement involved in extracellular fluid movement	STARD7 CFAP43 DNAH5 INVS DNAH1	5.56e-06	59	89	5	GO:0003351
GeneOntologyBiologicalProcess	extracellular transport	STARD7 CFAP43 DNAH5 INVS DNAH1	7.12e-06	62	89	5	GO:0006858
GeneOntologyBiologicalProcess	regulation of cell shape	PTK2B MYH14 MYO10 PLXND1 MARK2 ARAP1	6.55e-05	159	89	6	GO:0008360
GeneOntologyCellularComponent	cell cortex	SPTBN5 PTK2B TCHP MYO10 INSC SPTB SPTBN2 MACF1 MARK2 SLC4A1 EXOC4	5.64e-07	371	90	11	GO:0005938
GeneOntologyCellularComponent	spectrin	SPTBN5 SPTB SPTBN2	6.36e-06	9	90	3	GO:0008091
GeneOntologyCellularComponent	apical cortex	SPTBN5 TCHP INSC	9.06e-06	10	90	3	GO:0045179
GeneOntologyCellularComponent	cis-Golgi network	GOLGA8DP GBF1 AKAP9 GOLGA8CP GOLGA6L7	3.31e-05	85	90	5	GO:0005801
GeneOntologyCellularComponent	cell cortex region	SPTBN5 TCHP INSC MARK2	4.18e-05	45	90	4	GO:0099738
GeneOntologyCellularComponent	actin-based cell projection	MYO10 FARP1 CFTR UTRN CTSL CTSV EXOC4	1.99e-04	278	90	7	GO:0098858
GeneOntologyCellularComponent	cilium	SPTBN5 AKAP9 TCHP MROH2B CEP250 CFAP43 USP48 DNAH5 QRICH2 SPAG5 INVS DNAH1	4.60e-04	898	90	12	GO:0005929
GeneOntologyCellularComponent	9+2 motile cilium	AKAP9 MROH2B CFAP43 DNAH5 QRICH2 DNAH1	5.74e-04	238	90	6	GO:0097729
GeneOntologyCellularComponent	cell body	GHRH CACNA1A PTK2B AKAP9 MYO10 SPTBN2 CFTR RESP18 PLXND1 CTSL CTSV EXOC4	6.22e-04	929	90	12	GO:0044297
GeneOntologyCellularComponent	spectrin-associated cytoskeleton	SPTB SPTBN2	6.47e-04	9	90	2	GO:0014731
GeneOntologyCellularComponent	Golgi stack	GOLGA8DP GBF1 AKAP9 GOLGA8CP ARAP1	8.67e-04	171	90	5	GO:0005795
GeneOntologyCellularComponent	neuronal cell body	GHRH CACNA1A PTK2B AKAP9 MYO10 SPTBN2 CFTR RESP18 CTSL CTSV EXOC4	9.06e-04	835	90	11	GO:0043025
GeneOntologyCellularComponent	cytoplasmic region	SPTBN5 TCHP INSC CFAP43 MARK2 DNAH5 DNAH1	9.31e-04	360	90	7	GO:0099568
GeneOntologyCellularComponent	insulin-responsive compartment	PIKFYVE DENND4C	9.83e-04	11	90	2	GO:0032593
GeneOntologyCellularComponent	microvillus	CFTR CTSL CTSV EXOC4	1.97e-03	123	90	4	GO:0005902
MousePheno	abnormal R wave	DSP CTSL CTSV	4.71e-06	7	73	3	MP:0011919
MousePheno	abnormal T wave	DSP CTSL CTSV	1.12e-05	9	73	3	MP:0010505
MousePheno	periodontal ligament necrosis	CTSL CTSV	2.69e-05	2	73	2	MP:0030515
MousePheno	abnormal lymph node medullary sinus morphology	CTSL CTSV	2.69e-05	2	73	2	MP:0011222
MousePheno	dilated lymph node medullary sinus	CTSL CTSV	2.69e-05	2	73	2	MP:0011223
MousePheno	abnormal heart atrium morphology	PIKFYVE LEMD2 BAZ1B PLXND1 DNAH5 CTSL CTSV INVS	2.71e-05	232	73	8	MP:0003105
MousePheno	increased heart atrium size	PIKFYVE PLXND1 CTSL CTSV	9.46e-05	46	73	4	MP:0008725
MousePheno	abnormal heart echocardiography feature	DSP LEMD2 CTSL CTSV	1.21e-04	49	73	4	MP:0011925
MousePheno	abnormal ion homeostasis	PHEX PTK2B TRAP1 AKAP9 PIK3CD SPTB SPTBN2 CFTR BAZ1B RESP18 KCTD1 ASCC3 ECPAS DNAH5 GIMAP6 SLC4A1 EXOC4	1.59e-04	1232	73	17	MP:0001765
MousePheno	abnormal respiratory epithelial transmembrane transport	CFTR STARD7	1.60e-04	4	73	2	MP:0014026
MousePheno	abnormal heart atrium size	PIKFYVE PLXND1 CTSL CTSV	1.78e-04	54	73	4	MP:0031576
MousePheno	abnormal calcium ion homeostasis	PHEX PTK2B AKAP9 PIK3CD BAZ1B KCTD1 DNAH5 GIMAP6 SLC4A1	2.43e-04	404	73	9	MP:0004231
MousePheno	folliculitis	CTSL CTSV	2.66e-04	5	73	2	MP:0000376
MousePheno	dental pulp necrosis	CTSL CTSV	2.66e-04	5	73	2	MP:0013251
MousePheno	hair follicle outer root sheath hyperplasia	CTSL CTSV	2.66e-04	5	73	2	MP:0010688
MousePheno	enlarged thymus cortex	CTSL CTSV	2.66e-04	5	73	2	MP:0013593
MousePheno	increased circulating mineral level	SPTB SPTBN2 BAZ1B RESP18 KCTD1 ASCC3 ECPAS DNAH5 GIMAP6 SLC4A1 EXOC4	3.77e-04	626	73	11	MP:0014547
Domain	Spectrin_repeat	SPTBN5 DSP SPTB SPTBN2 MACF1 UTRN	3.74e-09	29	87	6	IPR002017
Domain	Spectrin/alpha-actinin	SPTBN5 DSP SPTB SPTBN2 MACF1 UTRN	7.05e-09	32	87	6	IPR018159
Domain	SPEC	SPTBN5 DSP SPTB SPTBN2 MACF1 UTRN	7.05e-09	32	87	6	SM00150
Domain	Actinin_actin-bd_CS	SPTBN5 SPTB SPTBN2 MACF1 UTRN	6.15e-08	23	87	5	IPR001589
Domain	Spectrin	SPTBN5 SPTB SPTBN2 MACF1 UTRN	6.15e-08	23	87	5	PF00435
Domain	ACTININ_2	SPTBN5 SPTB SPTBN2 MACF1 UTRN	6.15e-08	23	87	5	PS00020
Domain	ACTININ_1	SPTBN5 SPTB SPTBN2 MACF1 UTRN	6.15e-08	23	87	5	PS00019
Domain	CH	SPTBN5 EHBP1 SPTB SPTBN2 MACF1 UTRN	5.68e-07	65	87	6	SM00033
Domain	CH	SPTBN5 EHBP1 SPTB SPTBN2 MACF1 UTRN	8.86e-07	70	87	6	PF00307
Domain	-	SPTBN5 EHBP1 SPTB SPTBN2 MACF1 UTRN	9.64e-07	71	87	6	1.10.418.10
Domain	CH	SPTBN5 EHBP1 SPTB SPTBN2 MACF1 UTRN	1.14e-06	73	87	6	PS50021
Domain	CH-domain	SPTBN5 EHBP1 SPTB SPTBN2 MACF1 UTRN	1.34e-06	75	87	6	IPR001715
Domain	DUF4795	C16orf96 QRICH2	2.14e-05	2	87	2	IPR032013
Domain	DUF4795	C16orf96 QRICH2	2.14e-05	2	87	2	PF16043
Domain	MRFAP1	MRFAP1 MRFAP1L1	2.14e-05	2	87	2	IPR029254
Domain	MRFAP1	MRFAP1 MRFAP1L1	2.14e-05	2	87	2	PF15155
Domain	Spectrin_bsu	SPTB SPTBN2	1.28e-04	4	87	2	IPR016343
Domain	NUT	NUTM2F NUTM2G	2.13e-04	5	87	2	IPR024310
Domain	NUT_N	NUTM2F NUTM2G	2.13e-04	5	87	2	IPR024309
Domain	NUT	NUTM2F NUTM2G	2.13e-04	5	87	2	PF12881
Domain	GOLGA6L	GOLGA6L6 GOLGA6L2	3.18e-04	6	87	2	IPR026737
Domain	-	DSP MACF1	3.18e-04	6	87	2	3.90.1290.10
Domain	Plectin_repeat	DSP MACF1	4.44e-04	7	87	2	IPR001101
Domain	Inhibitor_I29	CTSL CTSV	4.44e-04	7	87	2	PF08246
Domain	Prot_inhib_I29	CTSL CTSV	4.44e-04	7	87	2	IPR013201
Domain	Inhibitor_I29	CTSL CTSV	4.44e-04	7	87	2	SM00848
Domain	Plectin	DSP MACF1	4.44e-04	7	87	2	PF00681
Domain	PLEC	DSP MACF1	4.44e-04	7	87	2	SM00250
Domain	PH_dom-spectrin-type	SPTBN5 SPTBN2	7.56e-04	9	87	2	IPR001605
Domain	Pept_asp_AS	CTSL CTSV	9.42e-04	10	87	2	IPR025661
Domain	Pept_his_AS	CTSL CTSV	1.15e-03	11	87	2	IPR025660
Domain	FERM_M	PTK2B MYO10 FARP1	1.28e-03	46	87	3	PF00373
Domain	-	PTK2B MYO10 FARP1	1.54e-03	49	87	3	1.20.80.10
Domain	FERM_central	PTK2B MYO10 FARP1	1.54e-03	49	87	3	IPR019748
Domain	FERM_domain	PTK2B MYO10 FARP1	1.54e-03	49	87	3	IPR000299
Domain	Pept_C1	CTSL CTSV	1.62e-03	13	87	2	SM00645
Domain	Peptidase_C1A_C	CTSL CTSV	1.62e-03	13	87	2	IPR000668
Domain	Peptidase_C1	CTSL CTSV	1.62e-03	13	87	2	PF00112
Domain	Peptidase_C1A	CTSL CTSV	1.62e-03	13	87	2	IPR013128
Domain	FERM_1	PTK2B MYO10 FARP1	1.63e-03	50	87	3	PS00660
Domain	FERM_2	PTK2B MYO10 FARP1	1.63e-03	50	87	3	PS00661
Domain	FERM_3	PTK2B MYO10 FARP1	1.63e-03	50	87	3	PS50057
Domain	Band_41_domain	PTK2B MYO10 FARP1	1.63e-03	50	87	3	IPR019749
Domain	B41	PTK2B MYO10 FARP1	1.63e-03	50	87	3	SM00295
Domain	FERM/acyl-CoA-bd_prot_3-hlx	PTK2B MYO10 FARP1	1.63e-03	50	87	3	IPR014352
Domain	Dynein_heavy_chain_D4_dom	DNAH5 DNAH1	1.88e-03	14	87	2	IPR024317
Domain	Dynein_HC_stalk	DNAH5 DNAH1	1.88e-03	14	87	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH5 DNAH1	1.88e-03	14	87	2	IPR013602
Domain	DHC_N2	DNAH5 DNAH1	1.88e-03	14	87	2	PF08393
Domain	MT	DNAH5 DNAH1	1.88e-03	14	87	2	PF12777
Domain	AAA_8	DNAH5 DNAH1	1.88e-03	14	87	2	PF12780
Domain	ATPase_dyneun-rel_AAA	DNAH5 DNAH1	1.88e-03	14	87	2	IPR011704
Domain	AAA_5	DNAH5 DNAH1	1.88e-03	14	87	2	PF07728
Domain	P-loop_NTPase	SBNO1 MYH14 MYO10 SUPV3L1 CFTR KIF14 ASCC3 DNAH5 DHX29 GIMAP6 DNAH1	1.90e-03	848	87	11	IPR027417
Domain	DHC_fam	DNAH5 DNAH1	2.17e-03	15	87	2	IPR026983
Domain	Dynein_heavy_dom	DNAH5 DNAH1	2.17e-03	15	87	2	IPR004273
Domain	Dynein_heavy	DNAH5 DNAH1	2.17e-03	15	87	2	PF03028
Domain	Pkinase_Tyr	ANKK1 PTK2B TEX14 MAP3K21	3.11e-03	129	87	4	PF07714
Domain	Ser-Thr/Tyr_kinase_cat_dom	ANKK1 PTK2B TEX14 MAP3K21	3.95e-03	138	87	4	IPR001245
Domain	PH	SPTBN5 MYO10 FARP1 SPTBN2 ARAP1	4.34e-03	229	87	5	PF00169
Domain	IQ	MYH14 MYO10 INVS	4.44e-03	71	87	3	PF00612
Pathway	REACTOME_INTERACTION_BETWEEN_L1_AND_ANKYRINS	SPTBN5 SPTB SPTBN2	9.98e-06	10	63	3	MM15112
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	EHBP1 L3MBTL2 DSP KIF14 ASCC3 ECPAS UTRN DENND4C SPAG5 EXOC4	1.69e-07	418	92	10	34709266
Pubmed	A germline-specific class of small RNAs binds mammalian Piwi proteins.	GOLGA8DP PTK2B SELENOS SPATA31E1 L3MBTL2 SBNO1 GOLGA8CP MRFAP1 SPTB MARK2	3.33e-07	450	92	10	16751776
Pubmed	BioID Performed on Golgi Enriched Fractions Identify C10orf76 as a GBF1 Binding Protein Essential for Golgi Maintenance and Secretion.	PIKFYVE GBF1 PATL1 ASCC3 ECPAS DHX29 DENND4C	1.81e-06	216	92	7	31519766
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	EHBP1 PTK2B GBF1 AKAP9 DSP KIF14 MACF1 MARK2 MAP3K21 UTRN DENND4C EXOC4	2.90e-06	861	92	12	36931259
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	GBF1 AKAP9 TCHP KIF14 MARK2 ECPAS MAP3K21 UTRN DENND4C	2.94e-06	446	92	9	24255178
Pubmed	The RNA binding protein MEX3A promotes tumor progression of breast cancer by post-transcriptional regulation of IGFBP4.	TRAP1 L3MBTL2 MYO10 FARP1 BAZ1B MACF1 DNAH5 CTSL	2.94e-06	332	92	8	37433992
Pubmed	Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.	TRAP1 MYH14 UBTF SUPV3L1 SPTB SPTBN2 LEMD2 KIF14 MSANTD4 KCTD1 MARK2	3.82e-06	732	92	11	34732716
Pubmed	Identification and developmental analysis of genes expressed by dopaminergic neurons of the substantia nigra pars compacta.	AKAP9 MYO10 MRFAP1 PATL1 MRFAP1L1	4.27e-06	90	92	5	15033168
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	GBF1 AKAP9 L3MBTL2 TCHP MYH14 MYO10 SUPV3L1 CEP250 BAZ1B NUTM2F GIMAP6 PABIR3 DENND4C NUTM2G	4.78e-06	1242	92	14	30973865
Pubmed	alphaII-betaV spectrin bridges the plasma membrane and cortical lattice in the lateral wall of the auditory outer hair cells.	SPTBN5 SPTB SPTBN2	5.03e-06	13	92	3	18796539
Pubmed	Acquisition of T regulatory function in cathepsin L-inhibited T cells by eye-derived CTLA-2alpha during inflammatory conditions.	CTSL CTSV	6.92e-06	2	92	2	19801522
Pubmed	Identification of procathepsin L (pCTS-L)-neutralizing monoclonal antibodies to treat potentially lethal sepsis.	CTSL CTSV	6.92e-06	2	92	2	36735789
Pubmed	Cathepsin L plays an active role in involution of the mouse mammary gland.	CTSL CTSV	6.92e-06	2	92	2	12815617
Pubmed	Cathepsin L promotes Vascular Intimal Hyperplasia after Arterial Injury.	CTSL CTSV	6.92e-06	2	92	2	28332696
Pubmed	Impaired turnover of autophagolysosomes in cathepsin L deficiency.	CTSL CTSV	6.92e-06	2	92	2	20536383
Pubmed	Response to comment on "Cathepsin-L influences the expression of extracellular matrix in lymphoid organs and plays a role in the regulation of thymic output and of peripheral T cell number".	CTSL CTSV	6.92e-06	2	92	2	16621972
Pubmed	Cathepsin L regulates pathogenicCD4 T cells in experimental autoimmune encephalomyelitis.	CTSL CTSV	6.92e-06	2	92	2	33540247
Pubmed	The protease cathepsin L regulates Th17 cell differentiation.	CTSL CTSV	6.92e-06	2	92	2	26343333
Pubmed	Lysosomal, cytoskeletal, and metabolic alterations in cardiomyopathy of cathepsin L knockout mice.	CTSL CTSV	6.92e-06	2	92	2	16636100
Pubmed	Cathepsin L Regulates Metabolic Networks Controlling Rapid Cell Growth and Proliferation.	CTSL CTSV	6.92e-06	2	92	2	31010818
Pubmed	Increased nucleolar localization of SpiA3G in classically but not alternatively activated macrophages.	CTSL CTSV	6.92e-06	2	92	2	20338168
Pubmed	Cathepsin L coexists with Cytotoxic T-lymphocyte Antigen-2 alpha in distinct regions of the mouse brain.	CTSL CTSV	6.92e-06	2	92	2	27586811
Pubmed	Autophagy and cathepsin L are involved in the antinociceptive effect of DMBC in a mouse acetic acid-writhing model.	CTSL CTSV	6.92e-06	2	92	2	23912553
Pubmed	Cathepsin L Helps to Defend Mice from Infection with Influenza A.	CTSL CTSV	6.92e-06	2	92	2	27716790
Pubmed	The radiation-induced nackt (nkt) allele is a loss-of-function mutation of the mouse cathepsin L gene.	CTSL CTSV	6.92e-06	2	92	2	16393949
Pubmed	Cathepsin L in bone marrow-derived cells is required for retinal and choroidal neovascularization.	CTSL CTSV	6.92e-06	2	92	2	20304958
Pubmed	Characterization and comparative mapping of the porcine CTSL gene indicates a novel synteny between HSA9q21-->q22 and SSC10q11-->q12.	CTSL CTSV	6.92e-06	2	92	2	11978977
Pubmed	Comparison of cathepsin L synthesized by normal and transformed cells at the gene, message, protein, and oligosaccharide levels.	CTSL CTSV	6.92e-06	2	92	2	2275556
Pubmed	The CD4 T cell-deficient mouse mutation nackt (nkt) involves a deletion in the cathepsin L (CtsI) gene.	CTSL CTSV	6.92e-06	2	92	2	11398968
Pubmed	A variant of pulmonary alveolar microlithiasis in nackt mice.	CTSL CTSV	6.92e-06	2	92	2	12014504
Pubmed	Utilization of spectrins βI and βIII in diagnosis of hepatocellular carcinoma.	SPTB SPTBN2	6.92e-06	2	92	2	30798076
Pubmed	Cathepsin L protects mice from mycoplasmal infection and is essential for airway lymphangiogenesis.	CTSL CTSV	6.92e-06	2	92	2	23600672
Pubmed	Mice that express enzymatically inactive cathepsin L exhibit abnormal spermatogenesis.	CTSL CTSV	6.92e-06	2	92	2	12533435
Pubmed	Cathepsin L was involved in vascular aging by mediating phenotypic transformation of vascular cells.	CTSL CTSV	6.92e-06	2	92	2	36206719
Pubmed	Cathepsin-L, a key molecule in the pathogenesis of drug-induced and I-cell disease-mediated gingival overgrowth: a study with cathepsin-L-deficient mice.	CTSL CTSV	6.92e-06	2	92	2	12466121
Pubmed	Sequence and expression of the cDNA for MEP (major excreted protein), a transformation-regulated secreted cathepsin.	CTSL CTSV	6.92e-06	2	92	2	3689328
Pubmed	Mutant cells selected during persistent reovirus infection do not express mature cathepsin L and do not support reovirus disassembly.	CTSL CTSV	6.92e-06	2	92	2	10516062
Pubmed	Lysosomal cysteine peptidase cathepsin L protects against cardiac hypertrophy through blocking AKT/GSK3beta signaling.	CTSL CTSV	6.92e-06	2	92	2	19096818
Pubmed	Cathepsin L deficiency as molecular defect of furless: hyperproliferation of keratinocytes and pertubation of hair follicle cycling.	CTSL CTSV	6.92e-06	2	92	2	11023992
Pubmed	Proteolytic processing of dynamin by cytoplasmic cathepsin L is a mechanism for proteinuric kidney disease.	CTSL CTSV	6.92e-06	2	92	2	17671649
Pubmed	Close relationship of the major excreted protein of transformed murine fibroblasts to thiol-dependent cathepsins.	CTSL CTSV	6.92e-06	2	92	2	3755373
Pubmed	[Effect of bushen tiaojing recipe and xiaoyao pill on expression of cathepsin-L mRNA in gonadotropin-primed mice].	CTSL CTSV	6.92e-06	2	92	2	21434350
Pubmed	Contribution of cathepsin L to secretome composition and cleavage pattern of mouse embryonic fibroblasts.	CTSL CTSV	6.92e-06	2	92	2	21972973
Pubmed	Cell type-specific functions of the lysosomal protease cathepsin L in the heart.	CTSL CTSV	6.92e-06	2	92	2	17942402
Pubmed	Cathepsin L stabilizes the histone modification landscape on the Y chromosome and pericentromeric heterochromatin.	CTSL CTSV	6.92e-06	2	92	2	16705169
Pubmed	The human cysteine protease cathepsin V can compensate for murine cathepsin L in mouse epidermis and hair follicles.	CTSL CTSV	6.92e-06	2	92	2	15679121
Pubmed	Complete nucleotide and deduced amino acid sequences of human and murine preprocathepsin L. An abundant transcript induced by transformation of fibroblasts.	CTSL CTSV	6.92e-06	2	92	2	2835398
Pubmed	Identification on melanoma cells of p39, a cysteine proteinase that cleaves C3, the third component of complement: amino-acid-sequence identities with procathepsin L.	CTSL CTSV	6.92e-06	2	92	2	8554545
Pubmed	Cathepsin L plays a major role in cholecystokinin production in mouse brain cortex and in pituitary AtT-20 cells: protease gene knockout and inhibitor studies.	CTSL CTSV	6.92e-06	2	92	2	19589362
Pubmed	Cathepsin L is essential for onset of autoimmune diabetes in NOD mice.	CTSL CTSV	6.92e-06	2	92	2	16184198
Pubmed	The lysosomal cysteine protease cathepsin L regulates keratinocyte proliferation by control of growth factor recycling.	CTSL CTSV	6.92e-06	2	92	2	16079282
Pubmed	Cathepsin L activity is essential to elastase perfusion-induced abdominal aortic aneurysms in mice.	CTSL CTSV	6.92e-06	2	92	2	21868704
Pubmed	Cathepsin-L contributes to cardiac repair and remodelling post-infarction.	CTSL CTSV	6.92e-06	2	92	2	21147810
Pubmed	Cathepsin L proteolytically processes histone H3 during mouse embryonic stem cell differentiation.	CTSL CTSV	6.92e-06	2	92	2	18957203
Pubmed	Identification of a membrane-associated cysteine protease with possible dual roles in the endoplasmic reticulum and protein storage vacuole.	CTSL CTSV	6.92e-06	2	92	2	11022031
Pubmed	B-cell lymphopoiesis is regulated by cathepsin L.	CTSL CTSV	6.92e-06	2	92	2	23585893
Pubmed	Cathepsin L: critical role in Ii degradation and CD4 T cell selection in the thymus.	CTSL CTSV	6.92e-06	2	92	2	9545226
Pubmed	Cathepsin L gene expression and promoter activation in rodent granulosa cells.	CTSL CTSV	6.92e-06	2	92	2	14563703
Pubmed	Cathepsin L is crucial for the development of early experimental diabetic nephropathy.	CTSL CTSV	6.92e-06	2	92	2	27575559
Pubmed	Dilated cardiomyopathy in mice deficient for the lysosomal cysteine peptidase cathepsin L.	CTSL CTSV	6.92e-06	2	92	2	11972068
Pubmed	Cathepsin L inhibition prevents murine autoimmune diabetes via suppression of CD8(+) T cell activity.	CTSL CTSV	6.92e-06	2	92	2	20877570
Pubmed	Cathepsin L inactivates human trypsinogen, whereas cathepsin L-deletion reduces the severity of pancreatitis in mice.	CTSL CTSV	6.92e-06	2	92	2	19900452
Pubmed	Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression.	CTSL CTSV	6.92e-06	2	92	2	25957406
Pubmed	Cloning, genomic organization, and chromosomal localization of human cathepsin L.	CTSL CTSV	6.92e-06	2	92	2	8419312
Pubmed	Thymocyte expression of cathepsin L is essential for NKT cell development.	CTSL CTSV	6.92e-06	2	92	2	12368909
Pubmed	Cloning and characterization of a mouse cysteine proteinase.	CTSL CTSV	6.92e-06	2	92	2	3533924
Pubmed	Surface activation of pro-cathepsin L.	CTSL CTSV	6.92e-06	2	92	2	1482371
Pubmed	Impaired hair follicle morphogenesis and cycling with abnormal epidermal differentiation in nackt mice, a cathepsin L-deficient mutation.	CTSL CTSV	6.92e-06	2	92	2	12163394
Pubmed	Expression of human cathepsin L or human cathepsin V in mouse thymus mediates positive selection of T helper cells in cathepsin L knock-out mice.	CTSL CTSV	6.92e-06	2	92	2	20347002
Pubmed	Cathepsin L-deficient mice exhibit abnormal skin and bone development and show increased resistance to osteoporosis following ovariectomy.	CTSL CTSV	6.92e-06	2	92	2	15154914
Pubmed	Cathepsin-L ameliorates cardiac hypertrophy through activation of the autophagy-lysosomal dependent protein processing pathways.	CTSL CTSV	6.92e-06	2	92	2	23608608
Pubmed	Developmental expression of cathepsin L and c-rasHa in the mouse placenta.	CTSL CTSV	6.92e-06	2	92	2	1751032
Pubmed	Inhibition of cathepsin L alleviates the microglia-mediated neuroinflammatory responses through caspase-8 and NF-κB pathways.	CTSL CTSV	6.92e-06	2	92	2	29154036
Pubmed	Peripheral cathepsin L inhibition induces fat loss in C. elegans and mice through promoting central serotonin synthesis.	CTSL CTSV	6.92e-06	2	92	2	31771567
Pubmed	Identification of quantitative trait loci that modify the severity of hereditary spherocytosis in wan, a new mouse model of band-3 deficiency.	SPTB SLC4A1	6.92e-06	2	92	2	15070709
Pubmed	Evolution of placentally expressed cathepsins.	CTSL CTSV	6.92e-06	2	92	2	12054558
Pubmed	Cathepsin L is involved in proliferation and invasion of breast cancer cells.	CTSL CTSV	6.92e-06	2	92	2	26639231
Pubmed	An alternate targeting pathway for procathepsin L in mouse fibroblasts.	CTSL CTSV	6.92e-06	2	92	2	11929604
Pubmed	Deficiency for the cysteine protease cathepsin L promotes tumor progression in mouse epidermis.	CTSL CTSV	6.92e-06	2	92	2	20023699
Pubmed	Impaired cathepsin L gene expression in skeletal muscle is associated with type 2 diabetes.	CTSL CTSV	6.92e-06	2	92	2	12941783
Pubmed	The lysosomal protease cathepsin L is an important regulator of keratinocyte and melanocyte differentiation during hair follicle morphogenesis and cycling.	CTSL CTSV	6.92e-06	2	92	2	12000732
Pubmed	Cathepsin-L influences the expression of extracellular matrix in lymphoid organs and plays a role in the regulation of thymic output and of peripheral T cell number.	CTSL CTSV	6.92e-06	2	92	2	15905545
Pubmed	Alterations during positive selection in the thymus of nackt CD4-deficient mice.	CTSL CTSV	6.92e-06	2	92	2	11119260
Pubmed	PIKfyve upregulates CFTR activity.	PIKFYVE CFTR	6.92e-06	2	92	2	19852935
Pubmed	Loss of responsiveness to IGF-I in cells with reduced cathepsin L expression levels.	CTSL CTSV	6.92e-06	2	92	2	18469859
Pubmed	Cortical Thymocytes Along With Their Selecting Ligands Are Required for the Further Thymic Maturation of NKT Cells in Mice.	CTSL CTSV	6.92e-06	2	92	2	32457751
Pubmed	Cloning and expression of the gene for the major excreted protein of transformed mouse fibroblasts. A secreted lysosomal protease regulated by transformation.	CTSL CTSV	6.92e-06	2	92	2	2826441
Pubmed	Inhibition of cysteine protease cathepsin L increases the level and activity of lysosomal glucocerebrosidase.	CTSL CTSV	6.92e-06	2	92	2	38329128
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	TARS3 SBNO1 DSP MYH14 SUPV3L1 MRFAP1 SPTB SPTBN2 MACF1 ZNF224 UTRN CTSL MRFAP1L1 EXOC4	7.04e-06	1285	92	14	35914814
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	AKAP9 L3MBTL2 TCHP UBTF FARP1 SPTBN2 BAZ1B MACF1 FASTKD2 ADI1 MARK2 ASCC3 USP48 DHX29 EXOC4	8.04e-06	1487	92	15	33957083
Pubmed	Proximity biotinylation and affinity purification are complementary approaches for the interactome mapping of chromatin-associated protein complexes.	TCHP MYH14 MRFAP1 KIF14 MPHOSPH8 USP48 UTRN DENND4C SPAG5 EXOC4	8.27e-06	645	92	10	25281560
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	DSP MYH14 UBTF SPTBN2 BAZ1B KIF14 MACF1 ASCC3 ECPAS UTRN	9.20e-06	653	92	10	22586326
Pubmed	Organization of focal adhesion plaques is disrupted by action of the HIV-1 protease.	SPTBN5 SPTB SPTBN2	1.42e-05	18	92	3	12119179
Pubmed	HENA, heterogeneous network-based data set for Alzheimer's disease.	PTK2B AKAP9 MACF1 SPAG5 EXOC4	1.74e-05	120	92	5	31413325
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	EHBP1 DSP MACF1 MARK2 ASCC3 ECPAS MAP3K21 DHX29 DENND4C EXOC4	1.84e-05	708	92	10	39231216
Pubmed	Inhibitory fragment from the p41 form of invariant chain can regulate activity of cysteine cathepsins in antigen presentation.	CTSL CTSV	2.07e-05	3	92	2	18362148
Pubmed	The PI3K regulatory subunits p55α and p50α regulate cell death in vivo.	CTSL CTSV	2.07e-05	3	92	2	24902901
Pubmed	Deletion of cysteine cathepsins B or L yields differential impacts on murine skin proteome and degradome.	CTSL CTSV	2.07e-05	3	92	2	23233448
Pubmed	Cathepsin L activity controls adipogenesis and glucose tolerance.	CTSL CTSV	2.07e-05	3	92	2	17643114
Pubmed	Invariant chain controls the activity of extracellular cathepsin L.	CTSL CTSV	2.07e-05	3	92	2	12417635
Interaction	PHF21A interactions	EHBP1 L3MBTL2 DSP KIF14 ASCC3 ECPAS UTRN DENND4C SPAG5 EXOC4	3.39e-06	343	91	10	int:PHF21A
Interaction	PHLDB2 interactions	DET1 CEP250 CFTR KIF14 PATL1 MAP3K21 DENND4C	3.85e-06	143	91	7	int:PHLDB2
Interaction	APC interactions	TRAP1 CEP250 SPTBN2 CFTR KIF14 MACF1 PATL1 MARK2 CTSV SPAG5	1.02e-05	389	91	10	int:APC
Interaction	CAMSAP2 interactions	AKAP9 TCHP KIF14 MACF1 MARK2 MAP3K21 DENND4C	1.15e-05	169	91	7	int:CAMSAP2
Interaction	PCNT interactions	AKAP9 TCHP FAM81B MRFAP1 SPTBN2 KIF14 MACF1 UTRN	1.35e-05	241	91	8	int:PCNT
Interaction	CEP170 interactions	AKAP9 TCHP FARP1 CEP250 CFTR KIF14 ASCC3 MRFAP1L1 SPAG5	1.37e-05	318	91	9	int:CEP170
Interaction	LCK interactions	PTK2B DSP FARP1 SPTBN2 KIF14 MACF1 MARK2 MAP3K21 UTRN EXOC4	4.53e-05	463	91	10	int:LCK
Interaction	RHOF interactions	PIKFYVE EHBP1 GBF1 FARP1 SPTBN2 KIF14 MACF1 FASTKD2 MARK2 ECPAS UTRN DENND4C	4.93e-05	673	91	12	int:RHOF
Interaction	FLOT1 interactions	EHBP1 FARP1 SPTBN2 CFTR KIF14 MACF1 MARK2 ECPAS UTRN STAT4	5.62e-05	475	91	10	int:FLOT1
Interaction	GOLGA6L6 interactions	GOLGA6L6 GOLGA6L2	6.03e-05	3	91	2	int:GOLGA6L6
Interaction	DCTN1 interactions	GBF1 SPTBN2 CFTR KIF14 MACF1 MARK2 ECPAS USP48 DHX29 SPAG5	8.18e-05	497	91	10	int:DCTN1
Interaction	MAPRE3 interactions	AKAP9 KIF14 MACF1 PATL1 MARK2 SPAG5 EXOC4	8.26e-05	230	91	7	int:MAPRE3
Interaction	LYN interactions	EHBP1 PTK2B DSP FARP1 SPTBN2 KIF14 MACF1 MARK2 MAP3K21 UTRN DENND4C SLC4A1	9.39e-05	720	91	12	int:LYN
Interaction	GSDME interactions	GBF1 CFTR KIF14 USP48	9.62e-05	53	91	4	int:GSDME
Interaction	SEC16A interactions	DET1 DSP MYO10 CEP250 CFTR KIF14 PATL1 CTSL STAT4	1.31e-04	426	91	9	int:SEC16A
Interaction	UBR4 interactions	SBNO1 MYO10 PTX3 CEP250 CFTR ECPAS DHX29 CTSL	1.35e-04	334	91	8	int:UBR4
Interaction	CAPZA2 interactions	DET1 FARP1 SPTBN2 CFTR KIF14 MACF1 MARK2 USP48 ARAP1	1.41e-04	430	91	9	int:CAPZA2
Interaction	PCM1 interactions	AKAP9 TCHP DSP FAM81B CEP250 KIF14 ECPAS SPAG5 EXOC4	1.51e-04	434	91	9	int:PCM1
Interaction	AURKB interactions	TARS3 TRAP1 GBF1 MAN2B1 DSP MYH14 KIF14 MACF1 MARK2 USP48 UTRN SPAG5	1.58e-04	761	91	12	int:AURKB
Interaction	GBF1 interactions	PIKFYVE GBF1 MROH2B KIF14 PATL1 ASCC3 ECPAS DHX29 DENND4C	1.73e-04	442	91	9	int:GBF1
Interaction	OFD1 interactions	EHBP1 TCHP DSP KIF14 DENND4C MRFAP1L1 SPAG5 EXOC4	1.75e-04	347	91	8	int:OFD1
Interaction	CTCFL interactions	TARS3 AKAP9 UBTF PATL1	1.78e-04	62	91	4	int:CTCFL
Interaction	CLIP1 interactions	TRAP1 AKAP9 TCHP CEP250 ECPAS EXOC4	1.82e-04	183	91	6	int:CLIP1
Interaction	GOLGA1 interactions	GBF1 TCHP MACF1 ASCC3 DENND4C EXOC4	1.82e-04	183	91	6	int:GOLGA1
Cytoband	15q11.2	GOLGA8DP GOLGA6L6 GOLGA6L2 GOLGA8CP	4.11e-04	172	92	4	15q11.2
Cytoband	Ensembl 112 genes in cytogenetic band chr9q22	SPATA31E1 NUTM2F CTSV NUTM2G	7.24e-04	200	92	4	chr9q22
Cytoband	Ensembl 112 genes in cytogenetic band chr15q11	GOLGA8DP GOLGA6L6 GOLGA6L2 GOLGA8CP	9.80e-04	217	92	4	chr15q11
Cytoband	12q24.11	TCHP FOXN4	2.01e-03	33	92	2	12q24.11
GeneFamily	EF-hand domain containing\|Spectrins	SPTBN5 SPTB SPTBN2	9.24e-07	7	55	3	1113
GeneFamily	EF-hand domain containing\|Plakins	DSP MACF1	2.51e-04	8	55	2	939
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	MYO10 FARP1 SPTB SPTBN2 ARAP1	4.01e-04	206	55	5	682
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTK2B MYO10 FARP1	4.72e-04	50	55	3	1293
GeneFamily	X-linked mental retardation\|RNA helicases	SUPV3L1 ASCC3	4.91e-04	11	55	2	1168
GeneFamily	Cathepsins	CTSL CTSV	9.30e-04	15	55	2	470
GeneFamily	Dyneins, axonemal	DNAH5 DNAH1	1.20e-03	17	55	2	536
GeneFamily	Ankyrin repeat domain containing	ANKK1 MPHOSPH8 ARAP1 INVS	6.26e-03	242	55	4	403
Coexpression	GSE27241_WT_VS_RORGT_KO_TH17_POLARIZED_CD4_TCELL_TREATED_WITH_DIGOXIN_UP	GBF1 SBNO1 MYO10 PIK3CD BAZ1B KIF14 MACF1 UTRN	1.86e-07	180	89	8	M8239
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	ATP13A4 DSP MYH14 FARP1 CFTR DNAH5	2.37e-06	185	92	6	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIK3CD NKAPD1 MPHOSPH8 GIMAP6 MRFAP1L1 STAT4	2.85e-06	191	92	6	9bb6a6b88f351217455765ba07a6acf11fda98f4
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell\|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)	PIK3CD NKAPD1 MPHOSPH8 GIMAP6 MRFAP1L1 STAT4	2.94e-06	192	92	6	1c0ce299cee9ab5cdea256f3e8c1e5598577a8b6
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A AKAP9 MYO10 MACF1 RESP18 ASCC3	3.21e-06	195	92	6	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 AKAP9 DSP MYH14 MAP3K21 UTRN	3.40e-06	197	92	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L2/3_IT\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SPTBN5 PTK2B KCTD1 SPAG5 STAT4	1.41e-05	148	92	5	d5cace5605bff2bb8248fadb51f2dad7539930ba
ToppCell	Control-Epithelial_airway-Ciliated_cells-Ciliated\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1 CCDC148	1.70e-05	154	92	5	4e3bc24043144143842627cacf6f90dda2228910
ToppCell	Control-Epithelial_airway-Ciliated_cells\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1 CCDC148	1.70e-05	154	92	5	7556a4b2b062da5ae7ec2bbb66e745e7662db628
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1 CCDC148	1.76e-05	155	92	5	5f1e2195a6b831e1b636f5cc3a282ca423721822
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1 CCDC148	1.76e-05	155	92	5	0944429459f642a1bcc56edc1ec28aaecde3e2dc
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 CTSV DNAH1	2.30e-05	164	92	5	e4d4c59aebe5cacd4ecdb907facd044dc82a831d
ToppCell	5'-Adult-Appendix-Epithelial-goblet-BEST2+_Goblet_cell\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN2 KCTD1 DNAH5 NUTM2G CCDC148	2.30e-05	164	92	5	29da0175bd3808a5b3039a6161c764105608ef96
ToppCell	5'-Adult-Appendix-Epithelial-goblet\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	SPTBN2 KCTD1 DNAH5 NUTM2G CCDC148	2.30e-05	164	92	5	e83b632ac7e1dace946991ddfe1fbfbbffc3a88b
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DSP CFTR CFAP43 CTSV	2.37e-05	165	92	5	1a114eacaab598f755a173a3fed842ba91f689dd
ToppCell	LPS-IL1RA-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DSP CFTR CFAP43 CTSV	2.37e-05	165	92	5	9cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC-PNEC_mature\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXDND1 SPTBN2 RESP18 SLC4A1 CCDC148	3.14e-05	175	92	5	8362a46f5804333baa84cd56d450bc147f372a7e
ToppCell	PND03-Epithelial-Epithelial_Airway-Neurosecretory-PNEC\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	AXDND1 SPTBN2 RESP18 SLC4A1 CCDC148	3.14e-05	175	92	5	8b4c62e608f0ec84e563bbf0ebffe3ed44085298
ToppCell	droplet-Limb_Muscle-MUSCLE-30m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP9 MYO10 BAZ1B ASCC3 UTRN	3.41e-05	178	92	5	01dafd19de04eff459253eaa9a35debf8f3deedf
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DSP MYH14 FARP1 UTRN	3.69e-05	181	92	5	b45b11428d13950369347e051d4d517efb2bd4fd
ToppCell	Control-Neu_4\|World / 5 Neutrophil clusters in COVID-19 patients	CACNA1A GBF1 KIF14 ECPAS UTRN	3.99e-05	184	92	5	ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCell	facs-Brain_Non-Myeloid-Cerebellum-24m-Epithelial-neuroepithelial_cell\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANKK1 KCTD1 CFAP43 DNAH5 DNAH1	4.10e-05	185	92	5	05bc89a566b0db90ae06506e067190a4739a0974
ToppCell	CV-Moderate-7\|Moderate / Virus stimulation, Condition and Cluster	GBF1 KIF14 MACF1 INVS EXOC4	4.10e-05	185	92	5	a6c9203ce6c2892a4a369c9bcfb85720f01cbb3f
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	MYO10 SPTBN2 CFTR MAP3K21 SLC4A1	4.10e-05	185	92	5	3d73b3e0bceb192257e5cfbe64b7ccb379b6e22d
ToppCell	LPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DSP MYH14 FARP1 UTRN	4.21e-05	186	92	5	3aebe163799109ffc67e4e10ee47c2dd0886a92c
ToppCell	CV-Moderate-7\|CV / Virus stimulation, Condition and Cluster	GBF1 KIF14 MACF1 INVS EXOC4	4.21e-05	186	92	5	8571956890fc9894d766ba294a28e376b4aba428
ToppCell	Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|World / Lineage, Cell type, age group and donor	ATP13A4 MYH14 FARP1 CFTR DNAH5	4.31e-05	187	92	5	81cc8435b2704a9a8287b3f54acaae0f11dd4ac7
ToppCell	LPS-antiTNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ATP13A4 DSP MYH14 FARP1 UTRN	4.31e-05	187	92	5	58d48128547ee3513d0bf7f78e61b76b1c472ca9
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	WSB1 ATP13A4 MYH14 FARP1 DNAH5	4.42e-05	188	92	5	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	WSB1 MYO10 SPTBN2 MAP3K21 SLC4A1	4.54e-05	189	92	5	a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCell	renal_medulla_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	MYO10 FARP1 UTRN EXOC4 CCDC148	4.54e-05	189	92	5	830d9cd0dd706bce22eb2416f07b2c31c870a05a
ToppCell	droplet-Lung-nan-18m-Epithelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DSP MYH14 CFTR C16orf96 DNAH1	4.65e-05	190	92	5	b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCell	CD8+_Memory_T_cell-CV-7\|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster	GBF1 MACF1 ZNF224 INVS EXOC4	4.77e-05	191	92	5	9454f642c3621370fa23640b631301346b300950
ToppCell	droplet-Heart-nan-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EHBP1 TARS3 DSP MYH14 SPTB	4.77e-05	191	92	5	97fb4232417a39801e87725755fd16a57c250209
ToppCell	droplet-Heart-nan-3m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	EHBP1 TARS3 DSP MYH14 SPTB	4.77e-05	191	92	5	64070a309d7e3f6001272409ab9ce206d0e7d73f
ToppCell	PND01-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	C16orf96 CFAP43 DNAH5 DNAH1 CCDC148	4.77e-05	191	92	5	96483adb97c81208aa513782550acd8a08b63866
ToppCell	droplet-Limb_Muscle-MUSCLE\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AKAP9 MYO10 MACF1 ASCC3 UTRN	5.14e-05	194	92	5	e3d63874111d1e8da3977329426e4dcf68d6de87
ToppCell	PCW_07-8.5-Epithelial-Epithelial_airway\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	ATP13A4 DSP MYH14 CFTR DNAH5	5.14e-05	194	92	5	f95c8dc242c9aebcadfe61b1ed033349cb7e5a88
ToppCell	BL-critical-LOC-Epithelial-unknown_epithelial\|LOC / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	TRAP1 FARP1 ZSCAN18 CFAP43 CCDC148	5.14e-05	194	92	5	6140ff8e776429c9593607da418b2d9c4f399d41
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A AKAP9 MACF1 RESP18 ASCC3	5.26e-05	195	92	5	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 DNAH5 UTRN	5.52e-05	197	92	5	b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCell	Control_saline-Epithelial_alveolar-AT_2-Differentiating_AT2\|Control_saline / Treatment groups by lineage, cell group, cell type	ATP13A4 AKAP9 DSP MYH14 UTRN	5.52e-05	197	92	5	44a59dfb889577b3160a5b13ada1276771a00241
ToppCell	COVID-19-Epithelial\|COVID-19 / Condition, Lineage and Cell class	DSP FAM81B MYH14 CFAP43 DNAH5	5.52e-05	197	92	5	18fd7344628a87d5c7ef5efb66e260a4136245bf
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	WSB1 ATP13A4 AKAP9 DSP CFTR	5.66e-05	198	92	5	285f729140b1df029c24f6ca1d2438470ac51794
ToppCell	Control_saline-Epithelial_alveolar-AT_1-Differentiating_AT1\|Control_saline / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.66e-05	198	92	5	85f424cd9bb3117c9e322031024aabb87696ce47
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.66e-05	198	92	5	b598ab958e31f1e98bd06dc0097b58ac3a3f90a3
ToppCell	Control_saline-Epithelial_alveolar-AT_1\|Control_saline / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.66e-05	198	92	5	9b161285df7a4e51618f3517cfc5b8221ba55786
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.79e-05	199	92	5	d43c605a4ff221cf78d91678c15d2ad20f831c7f
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.79e-05	199	92	5	1c70e7d6bd25980e1b92aa1cac3f3c95d9651b4b
ToppCell	LPS_IL1RA-Epithelial_alveolar-AT_1\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.79e-05	199	92	5	a270630626df614f8605abddb7dee7c4d74f6149
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_only / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.93e-05	200	92	5	2dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_1-Differentiating_AT1\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.93e-05	200	92	5	ddfb1f006365bf16203ee49f20200f68220cc288
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.93e-05	200	92	5	8683445ad5b70748c4a1f12eb77d47623085147e
ToppCell	distal-2-Epithelial\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSP FAM81B MYH14 CFAP43 DNAH5	5.93e-05	200	92	5	2fc1e95706f212bf18ecdf6eb5b3182ac98c9b52
ToppCell	medial-2-Epithelial\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSP FAM81B MYH14 CFAP43 DNAH5	5.93e-05	200	92	5	0079041c3e654c1ef77c492bdb2f31ce8f4b507b
ToppCell	Biopsy_IPF-Epithelial\|Biopsy_IPF / Sample group, Lineage and Cell type	DSP FAM81B MYH14 CFAP43 DNAH5	5.93e-05	200	92	5	76f1ac00b34d07057d8da03d276438b719b46b1d
ToppCell	LPS_only-Epithelial_alveolar-AT_1\|LPS_only / Treatment groups by lineage, cell group, cell type	ATP13A4 DSP MYH14 FARP1 UTRN	5.93e-05	200	92	5	9a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCell	medial-Epithelial\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	DSP FAM81B MYH14 CFAP43 DNAH5	5.93e-05	200	92	5	17bb9a9016058cbb70c7bd894c12f6208ff07895
ToppCell	droplet-Heart-HEART_(ALL_4:4:4:1:1)-30m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SBNO1 KIF14 SPAG5 STAT4	1.35e-04	126	92	4	4eeea015efe17e0aae5bd76b71fa70b5149dfada
ToppCell	TCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-4\|TCGA-Cervix / Sample_Type by Project: Shred V9	FOXN4 FARP1 CFAP43 CCDC148	2.14e-04	142	92	4	369f2e51e0283a4de70e6c7a3b95672c0838f205
ToppCell	ASK454-Epithelial-Type_2\|Epithelial / Donor, Lineage and Cell class of Lung cells from Dropseq	UBTF CFTR	2.69e-04	12	92	2	f8ea75314b9fa2bdc57564cad9640893a47f0340
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	DSP CFAP43 DNAH5 CCDC148	2.71e-04	151	92	4	8216462e723fec2797387929dde095370947e10a
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1	2.71e-04	151	92	4	81cf939ed4df9574fbfff265e109cb9f947d7e6e
ToppCell	LPS-IL1RA-Epithelial_airway-Ciliated_cells-Ciliated\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1	2.71e-04	151	92	4	9cbcbbc22965a9f0be8364e733d205dd64f2a533
ToppCell	facs-Aorta-Heart-24m-Myeloid-nan\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3CD SPTB STAT4 SLC4A1	2.78e-04	152	92	4	525d65c5c8e5580947367afdb1f6e68b49e9e5bb
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells-Ciliated\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1	2.92e-04	154	92	4	9ca71d440c4f87781e6525b8141e7d8d470b6a8e
ToppCell	LPS_only-Epithelial_airway-Ciliated_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 DNAH1	2.92e-04	154	92	4	58072ce422d09f2de602580325eaac6c4ec6c136
ToppCell	10x5'-Lung-Myeloid_Monocytic-Cycling_mono\|Lung / Manually curated celltypes from each tissue	SPTBN5 KIF14 SPAG5 INVS	3.07e-04	156	92	4	63b8cf14361b282872bc1c5b65d9fbc83e81a089
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN4 SPTB TEX14 SLC4A1	3.22e-04	158	92	4	9fd77ebdd1babf1c85a85d38d9a15858ab08bc84
ToppCell	facs-Marrow-KLS-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN4 SPTB TEX14 SLC4A1	3.22e-04	158	92	4	0edd9b005875f9a4f5446f5d5161f8ba63860793
ToppCell	frontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Pld5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	PTK2B MYH14 KCTD1 SPAG5	3.29e-04	159	92	4	a082e770fa757c4a1d3ed13d53f83297e36faf05
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A SPTB KIF14 SLC4A1	3.37e-04	160	92	4	9f24ee4fe1ba4590dce5dd4d43707fb007dca82f
ToppCell	kidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_principal_cell-Cortical_Collecting_Duct_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	WSB1 FOXN4 SPTBN2 MAP3K21	3.37e-04	160	92	4	7064af50fc10e3ea03badf415306222b74db0f95
ToppCell	droplet-Liver-Hepatocytes-24m-Lymphocytic-B_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CACNA1A SPTB KIF14 SLC4A1	3.37e-04	160	92	4	3b3b99305558f5b49d050fb9b249007630ea9085
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHEX SPTB SLC4A1 CCDC148	3.37e-04	160	92	4	56e6f4b82b5dc41c45f9d253c2db314a6f702b84
ToppCell	facs-Marrow-Granulocytes-18m-Hematologic-megakaryocyte-erythroid_progenitor_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PHEX SPTB SLC4A1 CCDC148	3.37e-04	160	92	4	bb1b966fb9e801db15e67d03e49db4609d6f935a
ToppCell	LPS-IL1RA-Epithelial_airway\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 CTSV	3.45e-04	161	92	4	472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCell	LPS_only-Epithelial_airway-Club_cells-Airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP CFAP43 DNAH5 CTSV	3.70e-04	164	92	4	b1243b10591e1e15a94952e39ffbf382eae6aae8
ToppCell	LPS_only-Epithelial_airway-Club_cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP CFAP43 DNAH5 CTSV	3.70e-04	164	92	4	c5b2001280a43da855017361a3f6071a0e492848
ToppCell	LPS_only-Epithelial_airway\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	DSP CFAP43 DNAH5 CTSV	3.70e-04	164	92	4	56e6934e6c7503a300d7be06762d45a1d6f1ae0f
ToppCell	facs-Marrow-B-cells-18m-Hematologic\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SELENOS SPTB TEX14 SLC4A1	3.79e-04	165	92	4	361a605d8f833d9ec54b120480dce397da35f9c3
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ATP13A4 FARP1 CFTR DNAH5	3.88e-04	166	92	4	c20479fe7a4306320d7f26e78bf956225f00f35a
ToppCell	15-Distal-Epithelial-Multiciliated_precursor\|Distal / Age, Tissue, Lineage and Cell class	FAM81B FOXN4 CFAP43 DNAH5	3.97e-04	167	92	4	442ea71a581ed5a547a214132b9f1b0243fd0895
ToppCell	E16.5-Endothelial-Endothelial_lymphatic\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTX3 ZNF235 UTRN GIMAP6	3.97e-04	167	92	4	b93103a868fba63a8910bffb690a6242b9252833
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTX3 ZNF235 UTRN GIMAP6	3.97e-04	167	92	4	fcd583b1efd0ac883379982ea8e6c54f2c0be268
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTX3 ZNF235 UTRN GIMAP6	3.97e-04	167	92	4	f6bc63138b7239211fa5f27a8dc799b6e022c0f8
ToppCell	E16.5-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTX3 ZNF235 UTRN GIMAP6	3.97e-04	167	92	4	26cd8ee5e826e71eaf58d10a906543a6932fb3f9
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TARS3 TXNL4A ZSCAN18 ZNF235	4.06e-04	168	92	4	32e4d82efaccf336d347e4063253c3635a3ec672
ToppCell	control-Myeloid-pDC\|Myeloid / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls	PHEX SUPV3L1 ZNF235 PABIR3	4.06e-04	168	92	4	affc39c7568b7df4b36af6f5b0e3702a18b6268c
ToppCell	15-Distal-Epithelial-Multiciliated_cell\|Distal / Age, Tissue, Lineage and Cell class	AXDND1 FAM81B CFAP43 DNAH5	4.15e-04	169	92	4	425d89ab69e9f9eb3df84056676423e390cc6ab1
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 CTSV	4.15e-04	169	92	4	8c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCell	LPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	FAM81B CFAP43 DNAH5 CTSV	4.15e-04	169	92	4	86041be5d3aeab5b9269f7912791b944f325a1b4
ToppCell	droplet-Lung-30m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PHEX UTRN GIMAP6 STAT4	4.34e-04	171	92	4	a8adce007ff4c713f71f2359b40cb3575b28c98d
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	SPTBN5 SPTB ZNF224 DENND4C	4.34e-04	171	92	4	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8\|lymph-node_spleen / Manually curated celltypes from each tissue	AKAP9 MACF1 UTRN STAT4	4.34e-04	171	92	4	2e9a20f8980b78325c52065a9c14ab3656267c05
ToppCell	facs-Lung-3m-Hematologic-lymphocytic-CD4-positive,_alpha-beta_T_cell-CD4-positive,_alpha-beta_T_cell_l21\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	L3MBTL2 PIK3CD FASTKD2 STAT4	4.34e-04	171	92	4	f1fdc0ec3399ed6955976d02be7e5fc329a64276
ToppCell	facs-Trachea-nan-24m-Epithelial-ciliated_columnar_cell_of_tracheobronchial_tree\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FOXN4 CFAP43 DNAH5 CCDC148	4.53e-04	173	92	4	27ae126c720f20d1fe116abbcd358e4cff8baf6b
ToppCell	droplet-Fat-Gat-18m-Epithelial\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR CFAP43 DNAH5 CCDC148	4.53e-04	173	92	4	f3f67531f72d6d52e19c7f1f2db1ab4026fb70da
ToppCell	droplet-Fat-Gat-18m-Epithelial-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR CFAP43 DNAH5 CCDC148	4.53e-04	173	92	4	a40a52d8041d45dc3bef74fe55945ae07aa018d6
ToppCell	droplet-Fat-Gat-18m-Epithelial-epithelial_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CFTR CFAP43 DNAH5 CCDC148	4.53e-04	173	92	4	f0b4dd1cf41d6ee6abb0e1968b8b39f4fabebcb5
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CACNA1A SPATA31E1 DSP C16orf96	4.63e-04	174	92	4	3503c7dec498597f76a86dbd5e4bb2311e743bde
Drug	AC1L1DW2	PIKFYVE SPTBN5 PTK2B SPTB SPTBN2 UTRN CTSL SLC4A1	7.47e-07	186	90	8	CID000002532
Drug	plakin	SPTBN5 DSP SPTB SPTBN2 MACF1 UTRN	8.87e-07	82	90	6	CID000018752
Drug	dimyristoylphosphatidylcholine	SPTBN5 SPTB SPTBN2 ADI1 SLC4A1	5.47e-06	64	90	5	CID000026197
Disease	Bronchiectasis	PIK3CD CFTR DNAH5	3.30e-05	22	84	3	C0006267
Disease	Elliptocytosis found	SPTB SLC4A1	4.79e-05	4	84	2	C0427480
Disease	Hereditary elliptocytosis	SPTB SLC4A1	4.79e-05	4	84	2	cv:C0013902
Disease	spinocerebellar ataxia type 5 (implicated_via_orthology)	SPTB SPTBN2	4.79e-05	4	84	2	DOID:0050882 (implicated_via_orthology)
Disease	Anemia, hereditary spherocytic hemolytic	SPTB SLC4A1	7.96e-05	5	84	2	C0221409
Disease	hereditary spherocytosis (is_implicated_in)	SPTB SLC4A1	7.96e-05	5	84	2	DOID:12971 (is_implicated_in)
Disease	Hereditary spherocytosis	SPTB SLC4A1	7.96e-05	5	84	2	cv:C0037889
Disease	Elliptocytosis, Hereditary	SPTB SLC4A1	1.19e-04	6	84	2	C0013902
Disease	Hereditary spherocytosis	SPTB SLC4A1	2.22e-04	8	84	2	C0037889
Disease	household income	AXDND1 GBF1 SBNO1 FARP1 ARAP1 EXOC4	2.36e-04	304	84	6	EFO_0009695
Disease	frontal fibrosing alopecia	EHBP1 CACNA1A MYO10	3.51e-04	48	84	3	EFO_0009855
Disease	Dental enamel hypoplasia	MYH14 MAP3K21	5.19e-04	12	84	2	EFO_1001304
Disease	migraine disorder	CACNA1A PTK2B INSC FARP1 BAZ1B MACF1	5.53e-04	357	84	6	MONDO_0005277
Disease	Anemia, Hemolytic, Acquired	SPTB SLC4A1	6.12e-04	13	84	2	C0002879
Disease	Anemia, Hemolytic	SPTB SLC4A1	6.12e-04	13	84	2	C0002878
Disease	Anemia, Microangiopathic	SPTB SLC4A1	6.12e-04	13	84	2	C0002889
Disease	Microangiopathic hemolytic anemia	SPTB SLC4A1	6.12e-04	13	84	2	C0221021
Disease	tetralogy of Fallot (implicated_via_orthology)	DNAH5 INVS	7.13e-04	14	84	2	DOID:6419 (implicated_via_orthology)
Disease	cathepsin L1 measurement	MAN2B1 CTSL	9.36e-04	16	84	2	EFO_0010619
Disease	unipolar depression, bipolar disorder	ATP13A4 L3MBTL2 MARK2 ASCC3	1.04e-03	156	84	4	EFO_0003761, MONDO_0004985
Disease	otitis media (biomarker_via_orthology)	CTSL CTSV	1.06e-03	17	84	2	DOID:10754 (biomarker_via_orthology)
Disease	Dermatologic disorders	AKAP9 PTX3 GOLGA6L7	1.30e-03	75	84	3	C0037274
Disease	depressive symptom measurement	ANKK1 EHBP1 CACNA1A L3MBTL2 FARP1 ASCC3	1.38e-03	426	84	6	EFO_0007006
Disease	otitis media (implicated_via_orthology)	PHEX DNAH5	1.78e-03	22	84	2	DOID:10754 (implicated_via_orthology)
Disease	triacylglycerol 58:9 measurement	GBF1 FASTKD2	1.78e-03	22	84	2	EFO_0010443
Disease	nephrotic syndrome (biomarker_via_orthology)	CTSL CTSV	2.12e-03	24	84	2	DOID:1184 (biomarker_via_orthology)
Disease	ergothioneine measurement	CACNA1A DNAH5	2.49e-03	26	84	2	EFO_0021163
Disease	cystic fibrosis (is_implicated_in)	PTX3 CFTR	2.68e-03	27	84	2	DOID:1485 (is_implicated_in)

Protein segments in the cluster

Peptide	Gene	Start	Entry
QQMDAELRKEMMAIW	CACNA1A	1916	O00555
NMVMKLEEQIRWYRQ	AKAP9	3611	Q99996
RILQIEWEHKKMEME	CFAP43	1496	Q8NDM7
EWEHKKMEMEREDLN	CFAP43	1501	Q8NDM7
KMEMEREDLNQKAWD	CFAP43	1506	Q8NDM7
KQKWQEMEMRDLQRL	CCDC148	426	Q8NFR7
CWEEAMEKMIENLRQ	CFTR	276	P13569
MDEKNQELRWMEAAR	SLC4A1	66	P02730
REQELREMAWSTMKQ	BTN3A1	286	O00481
VWEKNMKMIELHNGE	CTSV	51	O60911
EEAVIENRALWMMIK	ATP13A4	1126	Q4VNC1
METRQQMSAELWKER	BAZ1B	766	Q9UIG0
EAQQMVDLMKRCWDQ	ANKK1	256	Q8NFD2
LRQLRMWKMQLLDEN	DET1	326	Q7L5Y6
EEKNMEVNMKEWILR	DHX29	221	Q7Z478
DWQKMLDRLLTEMDN	QRICH2	1361	Q9H0J4
MEWKLEQSMREQALL	GOLGA8F;	1	Q08AF8
KLWEMDNMLIQIKTQ	MRFAP1L1	56	Q96HT8
MDLINRETMSEWKLQ	PABIR3	86	Q6P4D5
LQREKDWVSKIQMMQ	PATL1	406	Q86TB9
HQQERDMAEMQRVWK	KIF14	756	Q15058
DMAEMQRVWKEKFEQ	KIF14	761	Q15058
WRKLEEEEQAMYEMV	LEMD2	401	Q8NC56
QWEDVMKGMKVEVLN	L3MBTL2	206	Q969R5
EWIKSLMNNSKEEMR	ECPAS	696	Q5VYK3
KMQAQMKELWREVEE	MYH14	1666	Q7Z406
ERYWQKTLLQMEEME	PLXND1	1301	Q9Y4D7
QLQPMLLEMERWKQD	KCTD1	116	Q719H9
QKVEEEQMLDMWIKE	MYO10	1901	Q9HD67
QEQEEKMWEQEEKMR	GOLGA6L2	351	Q8N9W4
ERMREQEKMWEQVEK	GOLGA6L2	411	Q8N9W4
QEEMMWEKEEKIREL	GOLGA6L6	356	A8MZA4
KMWRQEEKIREQEEM	GOLGA6L6	506	A8MZA4
KMQEQEETMWRQEEK	GOLGA6L6	636	A8MZA4
QEEKMRRQEEKMWEQ	GOLGA6L6	696	A8MZA4
EQEEQMRKQEEQMWK	GOLGA6L7	371	A0A1B0GV03
MRKQEEQMWKQEEQI	GOLGA6L7	376	A0A1B0GV03
GEQEEQMRKQEEQMW	GOLGA6L7	391	A0A1B0GV03
ELLSWVEEMQMKLER	MACF1	591	Q9UPN3
VEEMQMKLERAEWGN	MACF1	596	Q9UPN3
MEKQIWGELETMQNE	FAM81B	391	Q96LP2
WKDDITQDAMIQKME	RESP18	116	Q5W5W9
MEEGEFKNWIEKMQA	PIKFYVE	1456	Q9Y2I7
VRIMMNEGKINQSEW	DNAH1	3531	Q9P2D7
DMADVWVKIQDVLQM	EXOC4	381	Q96A65
MEWKLEQSMREQALL	GOLGA8DP	1	Q0D2H9
LERIWGNQIEMMKDR	C16orf96	751	A6NNT2
RSEMEKWVEDIQMAI	FARP1	841	Q9Y4F1
MENDMKKLVAERDIW	AXDND1	386	Q5T1B0
ETNRENDKQETWMLM	DSP	656	P15924
NDKQETWMLMELQKI	DSP	661	P15924
ELMRKESQWQMEQEF	CEP250	151	Q9BV73
WQKKMTQLEMEIQEA	DENND4C	551	Q5VZ89
EEEAMMQEWFMLVNK	EHBP1	1111	Q8NDI1
LDYQDKWVRMQKLEM	MAN2B1	221	O00754
EQIMKDRWMNVGHED	MARK2	296	Q7KZI7
QVDSVQRWMEDLKLM	INSC	71	Q1MX18
EMKEMALEAIVQLWR	GBF1	516	Q92538
EEAQQLWEAEKVKMR	PTK2B	791	Q14289
ADLIDAEQRMKKSMW	SBNO1	576	A3KN83
MVLCNEVTKWMKDDI	DNAH5	4511	Q8TE73
MDLQLEWMKLEDFQK	MPHOSPH8	536	Q99549
WDKLFIMLENSQMRE	PTX3	56	P26022
LTRRANWMQKDLEEM	INVS	101	Q9Y283
EAEEEMQIQKSQWMK	NUTM2F	286	A1L443
EAEEEMQIQKSQWMK	NUTM2G	286	Q5VZR2
KLWEMDNMLIQIKTQ	MRFAP1	56	Q9Y605
NLARIDKMEEEMHKW	FOXN4	271	Q96NZ1
EVWKQMFQELMREVK	RTP3	6	Q9BQQ7
MMRDWEKFQEEAKNR	TARS3	386	A2RTX5
KKDLAEMQEWMTQAE	UTRN	1131	P46939
WQKEEMALKHMQAEL	SPAG5	771	Q96R06
MKQKEQEERMSLWAT	TEX14	766	Q8IWB6
QLRELMEKVEAIMWE	GIMAP6	211	Q6P9H5
SMQDDWKLEIQQMFD	MAP3K21	416	Q5TCX8
LVNNWEMDKLEMEDA	FASTKD2	671	Q9NYY8
ETLIAKRALMKMWQE	SPATA31E1	366	Q6ZUB1
DMLKQLEKEWMTQQT	SUPV3L1	746	Q8IYB8
KLLKTMMWDNVNAED	MROH2B	871	Q7Z745
GRQVDSMWAEQKQME	GHRH	76	P01286
NVMKRMAWEEIAQCV	MSANTD4	41	Q8NCY6
QDVAELMQWMEEKGL	SPTBN5	1321	Q9NRC6
VWEKNMKMIELHNQE	CTSL	51	P07711
ERKEWMQALQQAMAE	ARAP1	406	Q96P48
KQWLNMDEREMENII	ASCC3	1586	Q8N3C0
EESDMWKIRELEKQM	NKAPD1	26	Q6ZUT1
KRRQKIEMWDSMQEG	SELENOS	111	Q9BQE4
LLKKQQMLEWEMAVR	SPTBN2	1421	O15020
QMLEWEMAVREKEVE	SPTBN2	1426	O15020
VRELMLWMDEVNLQM	SPTBN2	1916	O15020
LMNTMLIEELQDWKR	STAT4	226	Q14765
LQMIQLMDVLWKQEG	PIK3CD	791	O00329
KKEMMEELVEGVRWA	PHEX	431	P78562
ARREQVMADVAWMKQ	TCHP	316	Q9BT92
VMADVAWMKQAIEEQ	TCHP	321	Q9BT92
LQMLLREEAKEMWEK	TCHP	346	Q9BT92
QVMSRRKEMNEKWEA	SPTB	1986	P11277
EKETEELMAWMRNVL	TRAP1	576	Q12931
QWLMPEARSKEQMLE	ZSCAN18	76	Q8TBC5
NEDSEGKEQRWEMVM	STARD7	131	Q9NQZ5
KINWAMEDKQEMVDI	TXNL4A	101	P83876
RVWDLKDDGNMMKVL	WSB1	196	Q9Y6I7
QKVWDKEGEMEVAMQ	nan	56	Q9H521
REEKIWMMKTAIQRE	ZNF224	61	Q9NZL3
NDRVKALKAMEMTWN	UBTF	506	P17480
KFEEWCIEMAEMRKQ	USP48	446	Q86UV5
MISQLEREEKLWMKE	ZNF235	56	Q14590
ARMEWKLEQSMREQA	GOLGA8CP	196	A6NN73
EDQWIRIFMEKGDMV	ADI1	111	Q9BV57