Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor

GLUD1 GLUD2

4.40e-0521332GO:0016639
GeneOntologyMolecularFunctionglutamate dehydrogenase [NAD(P)+] activity

GLUD1 GLUD2

4.40e-0521332GO:0004353
GeneOntologyMolecularFunctionglutamate dehydrogenase (NAD+) activity

GLUD1 GLUD2

4.40e-0521332GO:0004352
GeneOntologyMolecularFunctionglutamate dehydrogenase (NADP+) activity

GLUD1 GLUD2

4.40e-0521332GO:0004354
GeneOntologyMolecularFunctionNAD+ binding

PARP14 GLUD1 GLUD2

3.03e-04201333GO:0070403
GeneOntologyMolecularFunctionnucleotidyltransferase activity

PARP3 POLR1C TENT5C PARP14 TIPARP POLR3B

5.46e-041521336GO:0016779
GeneOntologyMolecularFunctiontransforming growth factor beta binding

ACVR2B ITGAV LTBP1

6.71e-04261333GO:0050431
DomainELFV_dehydrog_N

GLUD1 GLUD2

5.11e-0521342PF02812
DomainGlu/Leu/Phe/Val_DH_C

GLUD1 GLUD2

5.11e-0521342IPR006096
DomainGlu/Leu/Phe/Val_DH_dimer_dom

GLUD1 GLUD2

5.11e-0521342IPR006097
DomainGlu/Leu/Phe/Val_DH

GLUD1 GLUD2

5.11e-0521342IPR006095
DomainELFV_dehydrog

GLUD1 GLUD2

5.11e-0521342PF00208
DomainNAD_bind_Glu_DH

GLUD1 GLUD2

5.11e-0521342IPR033922
DomainGLFV_DEHYDROGENASE

GLUD1 GLUD2

5.11e-0521342PS00074
DomainELFV_dehydrog

GLUD1 GLUD2

5.11e-0521342SM00839
DomainGlu/Leu/Phe/Val_DH_AS

GLUD1 GLUD2

5.11e-0521342IPR033524
DomainFRG2

FRG2 FRG2B

1.53e-0431342PF15315
DomainFRG2

FRG2 FRG2B

1.53e-0431342IPR026245
DomainPoly(ADP-ribose)pol_cat_dom

PARP3 PARP14 TIPARP

2.28e-04171343IPR012317
DomainPARP_CATALYTIC

PARP3 PARP14 TIPARP

2.28e-04171343PS51059
DomainPARP

PARP3 PARP14 TIPARP

2.28e-04171343PF00644
Domain-

PARP3 PARP14 TIPARP

2.28e-041713433.90.228.10
DomainWGR_domain

PARP3 PARP14 TIPARP

6.55e-04241343IPR008893
Pubmed

CDX2 regulation by the RNA-binding protein MEX3A: impact on intestinal differentiation and stemness.

MEX3C MEX3A MEX3B

2.38e-074137323408853
Pubmed

Chromosomal assignment of 11 loci in the rat by mouse-rat somatic hybrids and linkage.

GLUD1 GLUD2 NOS2

5.95e-07513737873882
Pubmed

Identification and characterization of human Mex-3 proteins, a novel family of evolutionarily conserved RNA-binding proteins differentially localized to processing bodies.

MEX3C MEX3A MEX3B

1.19e-066137317267406
Pubmed

Characterization of cDNA clones in size-fractionated cDNA libraries from human brain.

SZT2 LINC00869 PLPPR4 MACF1 PLXNA2

2.86e-065613759455484
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

PALD1 HSPG2 SZT2 PIEZO1 NLRX1 NAGLU NSD1 ZNF236 PRAG1 GBA2 TNRC18 SARS2 USP40 SPEN UVRAG PCNT

7.84e-0611051371635748872
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

STBD1 TBC1D5 ZKSCAN5 TNRC18 NFE2L2 UBQLN3 SPEN UVRAG MEX3B PCNT

8.54e-064301371035044719
Pubmed

Interaction with 14-3-3 adaptors regulates the sorting of hMex-3B RNA-binding protein to distinct classes of RNA granules.

MEX3C MEX3A MEX3B

1.28e-0512137318779327
Pubmed

Glutamate Delta-1 Receptor Regulates Inhibitory Neurotransmission in the Nucleus Accumbens Core and Anxiety-Like Behaviors.

GLUD1 GLUD2

1.54e-052137234173171
Pubmed

Glutamate dehydrogenase is essential to sustain neuronal oxidative energy metabolism during stimulation.

GLUD1 GLUD2

1.54e-052137228621566
Pubmed

GluD1 knockout mice with a pure C57BL/6N background show impaired fear memory, social interaction, and enhanced depressive-like behavior.

GLUD1 GLUD2

1.54e-052137232078638
Pubmed

Development of mice with brain-specific deletion of floxed glud1 (glutamate dehydrogenase 1) using cre recombinase driven by the nestin promoter.

GLUD1 GLUD2

1.54e-052137223595828
Pubmed

Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways.

GLUD1 GLUD2

1.54e-052137221621574
Pubmed

Identification of the molecular dysfunction caused by glutamate dehydrogenase S445L mutation responsible for hyperinsulinism/hyperammonemia.

GLUD1 GLUD2

1.54e-052137228911206
Pubmed

Delineation of glutamate pathways and secretory responses in pancreatic islets with β-cell-specific abrogation of the glutamate dehydrogenase.

GLUD1 GLUD2

1.54e-052137222875990
Pubmed

Molecular basis of human glutamate dehydrogenase regulation under changing energy demands.

GLUD1 GLUD2

1.54e-052137215578726
Pubmed

Important role of Ser443 in different thermal stability of human glutamate dehydrogenase isozymes.

GLUD1 GLUD2

1.54e-052137215044002
Pubmed

Induction of excitatory and inhibitory presynaptic differentiation by GluD1.

GLUD1 GLUD2

1.54e-052137222138648
Pubmed

Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia.

GLUD1 GLUD2

1.54e-052137234220417
Pubmed

Expression of human GLUD1 and GLUD2 glutamate dehydrogenases in steroid producing tissues.

GLUD1 GLUD2

1.54e-052137226241911
Pubmed

Differential levels of glutamate dehydrogenase 1 (GLUD1) in Balb/c and C57BL/6 mice and the effects of overexpression of the Glud1 gene on glutamate release in striatum.

GLUD1 GLUD2

1.54e-052137221446915
Pubmed

IFP35 aggravates Staphylococcus aureus infection by promoting Nrf2-regulated ferroptosis.

IFI35 NFE2L2

1.54e-052137237777065
Pubmed

Amphiphysin-1 protein level changes associated with tau-mediated neurodegeneration.

AMPH MAPT

1.54e-052137222975846
Pubmed

GluD1 binds GABA and controls inhibitory plasticity.

GLUD1 GLUD2

1.54e-052137238060673
Pubmed

Gene expression patterns in the hippocampus during the development and aging of Glud1 (Glutamate Dehydrogenase 1) transgenic and wild type mice.

GLUD1 GLUD2

1.54e-052137224593767
Pubmed

Potentiation of neuronal activity by tonic GluD1 current in brain slices.

GLUD1 GLUD2

1.54e-052137237154294
Pubmed

Deletion of glutamate dehydrogenase 1 (Glud1) in the central nervous system affects glutamate handling without altering synaptic transmission.

GLUD1 GLUD2

1.54e-052137222924626
Pubmed

Nerve tissue-specific (GLUD2) and housekeeping (GLUD1) human glutamate dehydrogenases are regulated by distinct allosteric mechanisms: implications for biologic function.

GLUD1 GLUD2

1.54e-052137211032875
Pubmed

Localization of Human Glutamate Dehydrogenases Provides Insights into Their Metabolic Role and Their Involvement in Disease Processes.

GLUD1 GLUD2

1.54e-052137229943084
Pubmed

Glutamate dehydrogenase deficiency disrupts glutamate homeostasis in hippocampus and prefrontal cortex and impairs recognition memory.

GLUD1 GLUD2

1.54e-052137231898404
Pubmed

Birth and adaptive evolution of a hominoid gene that supports high neurotransmitter flux.

GLUD1 GLUD2

1.54e-052137215378063
Pubmed

Widening Spectrum of Cellular and Subcellular Expression of Human GLUD1 and GLUD2 Glutamate Dehydrogenases Suggests Novel Functions.

GLUD1 GLUD2

1.54e-052137227422263
Pubmed

Critical role of the cysteine 323 residue in the catalytic activity of human glutamate dehydrogenase isozymes.

GLUD1 GLUD2

1.54e-052137215750346
Pubmed

Tau accumulates in Crohn's disease gut.

MAPT NFE2L2

1.54e-052137232436623
Pubmed

Molecular cloning, structure and expression analysis of a full-length mouse brain glutamate dehydrogenase cDNA.

GLUD1 GLUD2

1.54e-05213721711373
Pubmed

Transcriptomic responses in mouse brain exposed to chronic excess of the neurotransmitter glutamate.

GLUD1 GLUD2

1.54e-052137220529287
Pubmed

Determination of glutamate dehydrogenase activity and its kinetics in mouse tissues using metabolic mapping (quantitative enzyme histochemistry).

GLUD1 GLUD2

1.54e-052137225124006
Pubmed

Unexpected histone H3 tail-clipping activity of glutamate dehydrogenase.

GLUD1 GLUD2

1.54e-052137223673664
Pubmed

Lack of evidence for direct ligand-gated ion channel activity of GluD receptors.

GLUD1 GLUD2

1.54e-052137239052831
Pubmed

Active modulation of human erythrocyte mechanics.

PIEZO1 NOS2

1.54e-052137232579474
Pubmed

Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice.

GLUD1 GLUD2

1.54e-052137224442550
Pubmed

The Amplifying Pathway of the β-Cell Contributes to Diet-induced Obesity.

GLUD1 GLUD2

1.54e-052137227137930
Pubmed

GDH-Dependent Glutamate Oxidation in the Brain Dictates Peripheral Energy Substrate Distribution.

GLUD1 GLUD2

1.54e-052137226440896
Pubmed

Study of structure-function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme.

GLUD1 GLUD2

1.54e-052137212742085
Pubmed

Mitochondrial targeting adaptation of the hominoid-specific glutamate dehydrogenase driven by positive Darwinian selection.

GLUD1 GLUD2

1.54e-052137218688271
Pubmed

The complex regulation of human glud1 and glud2 glutamate dehydrogenases and its implications in nerve tissue biology.

GLUD1 GLUD2

1.54e-052137222658952
Pubmed

Increases in anterograde axoplasmic transport in neurons of the hyper-glutamatergic, glutamate dehydrogenase 1 (Glud1) transgenic mouse: Effects of glutamate receptors on transport.

GLUD1 GLUD2

1.54e-052137238124277
Pubmed

Deletion of glutamate dehydrogenase in beta-cells abolishes part of the insulin secretory response not required for glucose homeostasis.

GLUD1 GLUD2

1.54e-052137219015267
Pubmed

Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum.

GLUD1 GLUD2

1.54e-052137219448744
Pubmed

Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription.

MSRA NFE2L2

1.54e-052137229649787
Pubmed

Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes the cooperative behavior of the enzyme.

GLUD1 GLUD2

1.54e-052137211950837
Pubmed

Comparative proximity biotinylation implicates the small GTPase RAB18 in sterol mobilization and biosynthesis.

PALD1 STBD1 TBC1D5 DBNL FAM91A1 SPAG9 GBA2 GRAMD1B CYB5B TMPO GOLGA5

1.66e-055681371137774976
Pubmed

CLEC16A interacts with retromer and TRIM27, and its loss impairs endosomal trafficking and neurodevelopment.

IQGAP2 SZT2 NLRX1 ENTR1 OBSL1 FAM91A1 SARS2 TFB1M GLUD1 GLUD2 TMPO

3.00e-056061371136538041
Pubmed

Family-wide analysis of poly(ADP-ribose) polymerase activity.

PARP3 PARP14 TIPARP

3.23e-0516137325043379
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PALD1 OBSL1 FAM91A1 GRAMD1B LRRTM2 MACF1 SPEN PLXNA2 PCNT

3.61e-05407137912693553
Pubmed

Polymorphisms revealed by PCR with single, short-sized, arbitrary primers are reliable markers for mouse and rat gene mapping.

GLUD1 GLUD2 KLK2

3.90e-051713731617216
Pubmed

Potential antioxidant, antiinflammatory, and proapoptotic anticancer activities of Kakadu plum and Illawarra plum polyphenolic fractions.

NFE2L2 NOS2

4.61e-053137221875324
Pubmed

The structure of apo human glutamate dehydrogenase details subunit communication and allostery.

GLUD1 GLUD2

4.61e-053137212054821
Pubmed

Endocrine and Growth Abnormalities in 4H Leukodystrophy Caused by Variants in POLR3A, POLR3B, and POLR1C.

POLR1C POLR3B

4.61e-053137233005949
Pubmed

Sanfilippo syndrome type B, a lysosomal storage disease, is also a tauopathy.

MAPT NAGLU

4.61e-053137219416848
Pubmed

Trans-Synaptic Signaling through the Glutamate Receptor Delta-1 Mediates Inhibitory Synapse Formation in Cortical Pyramidal Neurons.

GLUD1 GLUD2

4.61e-053137231704028
Pubmed

Hepatocellular iNOS protects liver from NASH through Nrf2-dependent activation of HO-1.

NFE2L2 NOS2

4.61e-053137231043271
Pubmed

Nitric oxide-mediated regulation of ferroportin-1 controls macrophage iron homeostasis and immune function in Salmonella infection.

NFE2L2 NOS2

4.61e-053137223630227
Pubmed

Testis-enriched ferlin, FER1L5, is required for Ca2+-activated acrosome reaction and male fertility.

FER1L6 FER1L4

4.61e-053137236696506
Pubmed

POLR3-Related Leukodystrophy

POLR1C POLR3B

4.61e-053137222855961
Pubmed

NRF2 interacts with distal enhancer and inhibits nitric oxide synthase 2 expression in KRAS-driven pancreatic cancer cells.

NFE2L2 NOS2

4.61e-053137237852325
Pubmed

Increased expression of BIN1 mediates Alzheimer genetic risk by modulating tau pathology.

AMPH MAPT

4.61e-053137223399914
Pubmed

Postsynaptic δ1 glutamate receptor assembles and maintains hippocampal synapses via Cbln2 and neurexin.

GLUD1 GLUD2

4.61e-053137229784783
Pubmed

Methionine sulfoxide reductase A attenuates heme oxygenase-1 induction through inhibition of Nrf2 activation.

MSRA NFE2L2

4.61e-053137223036869
Pubmed

Genomic analysis of human chromosome 10q and 4q telomeres suggests a common origin.

FRG2 FRG2B

4.61e-053137211829491
Pubmed

Glutamine-Elicited Secretion of Glucagon-Like Peptide 1 Is Governed by an Activated Glutamate Dehydrogenase.

GLUD1 GLUD2

4.61e-053137229229616
Pubmed

Liver Glutamate Dehydrogenase Controls Whole-Body Energy Partitioning Through Amino Acid-Derived Gluconeogenesis and Ammonia Homeostasis.

GLUD1 GLUD2

4.61e-053137230002133
Pubmed

Glutamate delta-1 receptor regulates cocaine-induced plasticity in the nucleus accumbens.

GLUD1 GLUD2

4.61e-053137230315226
Pubmed

Meiotic Cas9 expression mediates gene conversion in the male and female mouse germline.

SPO11 DDX4

4.61e-053137234941868
Pubmed

Isolation of a human brain cDNA for glutamate dehydrogenase.

GLUD1 GLUD2

4.61e-05313723585334
Pubmed

GOT1 regulates CD8+ effector and memory T cell generation.

GLUD1 GLUD2

4.61e-053137236640309
Pubmed

Filamentous recombinant human Tau activates primary astrocytes via an integrin receptor complex.

MAPT ITGAV

4.61e-053137233398028
Pubmed

Screening for new inhibitors of the human Mitochondrial Pyruvate Carrier and their effects on hepatic glucose production and diabetes.

GLUD1 GLUD2

4.61e-053137237871770
Pubmed

Deletion of glutamate delta-1 receptor in mouse leads to enhanced working memory and deficit in fear conditioning.

GLUD1 GLUD2

4.61e-053137223560106
Pubmed

Mechanism of hyperinsulinism in short-chain 3-hydroxyacyl-CoA dehydrogenase deficiency involves activation of glutamate dehydrogenase.

GLUD1 GLUD2

4.61e-053137220670938
Pubmed

FRG2, an FSHD candidate gene, is transcriptionally upregulated in differentiating primary myoblast cultures of FSHD patients.

FRG2 FRG2B

4.61e-053137215520407
Pubmed

Identification of disulfide bond formation between MitoNEET and glutamate dehydrogenase 1.

GLUD1 GLUD2

4.61e-053137224295216
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

TBC1D19 CDH26 RTEL1 MYO9A MAPT MAN1C1 TBC1D5 DAB1 ACVR2B ZNF236 TMEM255B LRCH3 MSRA TNRC18 USP40 MACF1 PCNT

8.16e-0514891371728611215
Pubmed

The presence of two types of prorenin converting enzymes in the mouse submandibular gland.

KLK13 KLK2

9.19e-05413721959648
Pubmed

Enriched expression of GluD1 in higher brain regions and its involvement in parallel fiber-interneuron synapse formation in the cerebellum.

GLUD1 GLUD2

9.19e-054137224872547
Pubmed

Short-Term In Vitro ROS Detection and Oxidative Stress Regulators in Epiretinal Membranes and Vitreous from Idiopathic Vitreoretinal Diseases.

NFE2L2 NOS2

9.19e-054137236567907
Pubmed

Essential role of GluD1 in dendritic spine development and GluN2B to GluN2A NMDAR subunit switch in the cortex and hippocampus reveals ability of GluN2B inhibition in correcting hyperconnectivity.

GLUD1 GLUD2

9.19e-054137225721396
Pubmed

Control of disease tolerance to malaria by nitric oxide and carbon monoxide.

NFE2L2 NOS2

9.19e-054137224981859
Pubmed

The mTORC1 pathway stimulates glutamine metabolism and cell proliferation by repressing SIRT4.

GLUD1 GLUD2

9.19e-054137223663782
Pubmed

LRCH proteins: a novel family of cytoskeletal regulators.

LRCH3 LRCH4

9.19e-054137220805893
Pubmed

Prorenin processing and restricted endoproteolysis by mouse tissue kallikrein family enzymes (mK1, mK9, mK13, and mK22).

KLK13 KLK2

9.19e-05413729507064
Pubmed

GLUD1 determines murine muscle stem cell fate by controlling mitochondrial glutamate levels.

GLUD1 GLUD2

9.19e-054137239121856
Pubmed

A restriction fragment length polymorphism at murine Glud locus co-segregates with Rib-1, Es-10, and Tcra on chromosome 14.

GLUD1 GLUD2

9.19e-05413722566156
Pubmed

Disabled-1 binds to the cytoplasmic domain of amyloid precursor-like protein 1.

DAB1 APLP2

9.19e-054137210460257
Pubmed

Mouse glandular kallikrein genes: identification and characterization of the genes encoding the epidermal growth factor binding proteins.

KLK13 KLK2

9.19e-05413723322387
Pubmed

Latent TGF-β structure and activation.

ITGAV LTBP1

9.19e-054137221677751
Pubmed

Golgin-84-associated Golgi fragmentation triggers tau hyperphosphorylation by activation of cyclin-dependent kinase-5 and extracellular signal-regulated kinase.

MAPT GOLGA5

9.19e-054137224368089
Pubmed

Negative feedback regulation of lipopolysaccharide-induced inducible nitric oxide synthase gene expression by heme oxygenase-1 induction in macrophages.

NFE2L2 NOS2

9.19e-054137218022235
Pubmed

Mouse submandibular gland prorenin-converting enzyme is a member of glandular kallikrein family.

KLK13 KLK2

9.19e-05413721918045
Pubmed

TAF4b promotes mouse primordial follicle assembly and oocyte survival.

SPAG9 DDX4

9.19e-054137224836512
Pubmed

Meiotic gatekeeper STRA8 suppresses autophagy by repressing Nr1d1 expression during spermatogenesis in mice.

SPO11 UVRAG DDX4

1.00e-0423137331059511
GeneFamilyZinc fingers|Zinc fingers PARP-type|Poly(ADP-ribose) polymerases

PARP3 PARP14 TIPARP

5.84e-0517823684
GeneFamilyFerlin family

FER1L6 FER1L4

3.01e-046822828
GeneFamilyKallikreins

KLK13 KLK2

2.34e-0316822616
GeneFamilyWiskott-Aldrich Syndrome protein family

WASHC1 WASH2P

2.34e-031682214
CoexpressionAtlasdev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k-means-cluster#3_top-relative-expression-ranked_1000

MYO9A FOSB DAB1 CPA2 GK5 TIPARP MEX3C LTBP1

2.63e-051911328gudmap_dev gonad_e13.5_F_VascAssocMesenchStromOvary_MafB_k3_1000
CoexpressionAtlasdev gonad_e11.5_M_GonadVasMes_Flk_top-relative-expression-ranked_1000

STBD1 LIN28B MYO9A INHBB FOSB OBSL1 CPA2 GK5 TIPARP MEX3C MEX3A ASXL3 USP40 LTBP1 MEX3B PLXNA2

5.62e-0582713216gudmap_dev gonad_e11.5_M_GonadVasMes_Flk_1000
CoexpressionAtlasMESO-30 blastocyst_vs_MESO-30 amniotic fluid MSC-Confounder_removed-fold2.0_adjp0.05

HSPG2 BNIP5 STBD1 IQGAP2 MAPT PIEZO1 DENND1C ITGAV PRAG1 ITIH2 IFNAR2 GLUD1 GLUD2 KYNU PLTP

7.92e-0576113215PCBC_ratio_MESO-30 blastocyst_vs_MESO-30 amniotic fluid MSC_cfr-2X-p05
CoexpressionAtlasdev gonad_e11.5_F_GonadVasMes_Flk_k-means-cluster#1_top-relative-expression-ranked_1000

SZT2 MYO9A FOSB CPA2 GK5 TIPARP PKP2 PLXNA2

8.12e-052241328gudmap_dev gonad_e11.5_F_GonadVasMes_Flk_k1_1000
CoexpressionAtlasdev gonad_e11.5_M_SupCellPrec_Sry_top-relative-expression-ranked_500

MYO9A INHBB FOSB OBSL1 CPA2 GK5 TIPARP MEX3C IFNAR2 TNRC18 PKP2

8.30e-0543213211gudmap_dev gonad_e11.5_M_SupCellPrec_Sry_500
CoexpressionAtlasdev gonad_e11.5_M_GonMes_Sma_k-means-cluster#4_top-relative-expression-ranked_1000

FOSB OBSL1 CPA2 GK5 TIPARP MEX3C TNRC18 PKP2

1.01e-042311328gudmap_dev gonad_e11.5_M_GonMes_Sma_k4_1000
CoexpressionAtlasdev gonad_e12.5_F_VasAssMesen_MafB_top-relative-expression-ranked_1000

SZT2 MYO9A FOSB DAB1 OBSL1 CPA2 GK5 TIPARP MEX3C IFNAR2 TFB1M ASXL3 USP40 LTBP1 PLXNA2

1.09e-0478313215gudmap_dev gonad_e12.5_F_VasAssMesen_MafB_1000
ToppCelldroplet-Lung-nan-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NAGLU DENND1C MMP25 DGLUCY PLPPR4 UVRAG KYNU

1.25e-06176137724b2e94ee5defcefb64a1f2447a2cc71b015b0fd
ToppCellfacs-Lung-Endomucin-3m-Myeloid-Myeloid_Dendritic_Type_2|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRX1 KIF24 TNRC18 UVRAG KYNU MAP4K2

1.27e-051661376a2ce44702a0cd5fa5872cac3302d3c451205feef
ToppCellfacs-Lung-Endomucin-3m-Myeloid-myeloid_dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NLRX1 KIF24 TNRC18 UVRAG KYNU MAP4K2

1.27e-0516613760f641302a6b71c4badaaf20f51162bfc2386b167
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-T_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 DENND1C MEX3C MMP25 MTMR7 SARS2

1.50e-051711376246fc7edcefc47437d1df6029f295aca3b34b2b2
ToppCellfacs-Lung-ENDOMUCIN-18m-Lymphocytic-Ly6g5b+_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

IQGAP2 DENND1C MEX3C MMP25 MTMR7 SARS2

1.50e-0517113761fb4e11f92b48dc2d6e553c22e2571bbd8c223c6
ToppCellAdult-Epithelial-lung_goblet_cell-D231|Adult / Lineage, Cell type, age group and donor

CHL1 CDH26 TENT5C FER1L6 ASXL3 KLK13

1.66e-0517413767d2f802f493f19a068e097b2909a9000e2160266
ToppCelldroplet-Lung-18m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

NAGLU DENND1C MMP25 DGLUCY PLPPR4 KYNU

1.83e-051771376f360f7099570d248531897b96e0de282e58f59e9
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 MYO9A PP2D1 DNAI7 SPEN NOS2

1.83e-05177137614fb8d182775dfd0e49aa7e4e12543a85b3b8bd6
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-Lgr5-_amplifying_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA19 LIN28B KCP LCP2 NOS2

2.11e-051081375fcc26843a8788f0fe3cec14dcae083830da80b8f
ToppCellfacs-Large_Intestine-Distal-24m-Epithelial-epithelial_cell_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SPATA19 LIN28B KCP LCP2 NOS2

2.11e-051081375c1c68e328fdf5216f23845b4de9a3b1bbe61b11c
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Peritubular_Capilary_Endothelial_Cell_|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 HSPG2 INHBB TMEM255B NOS2 PLXNA2

2.20e-051831376dc19857b66dcadbf7c87de91f7b1f4e8ef2857ed
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 HSPG2 INHBB TMEM255B NOS2 PLXNA2

2.20e-0518313764759560e5b4f4e5a00e5f933e3451a27c7c4aefe
ToppCellFrontal_cortex-Endothelial|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

HSPG2 PARP14 IFI35 TRIP10 FZD6 PLTP

2.57e-051881376a43392dbd10fc7dbfb31be39b8af8a7ea121c894
ToppCellLPS_only-Unknown-Endothelial|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 PALD1 MAPT SGCG KCP

2.85e-051151375ad5298c2ad8bf94fa13c2e50b0799e929473ef59
ToppCellLPS_only-Unknown|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 PALD1 MAPT SGCG KCP

2.85e-0511513757a733f6987b40ec497a03734b79ed5355ad3a2fc
ToppCellLPS_only-Unknown-Endothelial-Pericyte_2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

EFCAB5 PALD1 MAPT SGCG KCP

2.85e-051151375c67145d3cd9243994a141749b426ff2a6dcc8d93
ToppCell5'-Adult-LargeIntestine-Hematopoietic-T_cells-TRGV4_gdT|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THEMIS FOSB TENT5C LCP2 TIPARP NCR1

2.89e-051921376f4b5a55a648e366234079411b6fdd2da75a4740e
ToppCelldroplet-Mammary_Gland-nan-3m-Epithelial-luminal_epithelial_cell_of_mammary_gland|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB PRAG1 ITIH2 MTMR7 FER1L4 RAPGEFL1

3.06e-051941376715e02e5f3250b1bfdc26b7dfd656ba4e705ea84
ToppCellCOVID-19-kidney-PLVAP+EC|kidney / Disease (COVID-19 only), tissue and cell type

PALD1 HSPG2 INHBB PCDH12 TMEM255B MACF1

3.15e-051951376a436483fec137584611f86b7a498a4dc2aa19cd3
ToppCellNeuron-Postmitotic-Excitatory_Neuron_-Newborn-41|World / Primary Cells by Cluster

AMPH MAPT MSRA EIF4A2 PKP2 PLXNA2

3.24e-051961376dee0984cd63a1a2fdebb4421af48ab566a5b684e
ToppCellCOVID-19-lung-Macrophage_metabolically_active|COVID-19 / Disease (COVID-19 only), tissue and cell type

HK3 IQGAP2 LCP2 PARP14 KYNU PLTP

3.24e-0519613761b7928f4eee94d4bb6ea410bab68a471dba12979
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

HK3 IQGAP2 GLT1D1 LCP2 GRAMD1B KYNU

3.33e-0519713763896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellParenchyma_COVID-19-Endothelial-TX-Lymphatic|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

PALD1 HSPG2 PIEZO1 PCDH12 TMEM255B MAP4K2

3.53e-05199137688f33b8dcd837abfa1d12c28719e073a7da6e979
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 HSPG2 PIEZO1 PCDH12 TMEM255B MAP4K2

3.53e-05199137664b19aff72e2a109cb5857cb248bd4712dd49b43
ToppCellBrain_organoid-organoid_Velasco_nature-6_mon-Radial_glial-oRG/Astroglia|6_mon / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 FOSB OBSL1 NFE2L2 LTBP1 PLTP

3.53e-0519913760b96fad1be02f0fe7a608207770cc56a6b6b291e
ToppCellLung_Parenchyma-Severe-Endothelial-Endothelial-Lymphatic-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

PALD1 HSPG2 PIEZO1 PCDH12 TMEM255B MAP4K2

3.53e-0519913762b9e1e069b36b3a61cc3e384f4523687b0e03905
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-gdT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

THEMIS IQGAP2 LCP2 MMP25 NCR1 MEX3B

3.63e-0520013761779a8ff4443a85ac500f849764e86d9c7529b84
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Radial_glial|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

IQGAP2 OBSL1 NFE2L2 GLUD1 LTBP1 PLTP

3.63e-052001376ed4a41cb6782541d8fc928aaa12cf03bc1c630a2
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L6b-L6b_VISp_Col8a1_Rxfp1|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

CHRNA6 SPATA19 SYNC IFI35 KYNU

5.32e-05131137581efe8b0ca4377e557a42ddb12aecaf3f46b15bf
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

EFCAB5 MEX3C ASXL3 SPEN RBM17

6.14e-0513513753351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Chodl|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

STBD1 INHBB IFI35 TMEM255B FER1L6

6.58e-0513713755cb84392e4483f50e09fb7395e2ec98f3eb6ecf3
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIN28B PLPPR4 ASXL3 LRRTM2 NCR1

7.30e-0514013757ca49bd7ba9381e75c10f888775df17e5d46804d
ToppCellfacs-Marrow-B-cells-24m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIN28B PLPPR4 ASXL3 LRRTM2 NCR1

7.30e-0514013751a31bc33d5723b9bc528cc0047ca5f4c80531c7a
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

TPP2 SZT2 ACVR2B ASXL3 SPEN

9.79e-051491375768877bade04ca0321593b8470b5011ad8270431
ToppCellfacs-Brain_Non-Myeloid-Hippocampus_-18m-Epithelial-neuronal_stem_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LIN28B SYNC DENND1C PKP2 MEX3B

1.01e-04150137547ea08d7609e1d2382bf56ef9e5c767e3597cf93
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 FOSB GK5 MTMR7 LRRTM2

1.08e-041521375b61d2f6ee819c8dd4b4b601a8bc8388b1983de58
ToppCellRV-17._Lymphocyte|RV / Chamber and Cluster_Paper

THEMIS IQGAP2 DENND1C LCP2 MMP25

1.11e-041531375e1ea621184014415870e00d511386b8cc3e0833b
ToppCellRV-17._Lymphocyte|World / Chamber and Cluster_Paper

THEMIS IQGAP2 DENND1C LCP2 MMP25

1.18e-041551375189276a3b400b2202e6681e23732e6452bfe704e
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3 CDH26 MMP25 DGLUCY PLPPR4

1.21e-041561375095281ea78aefa0ee638191a03f8d6f62a86a9ff
ToppCellPND03-Immune-Immune_Myeloid-DC-maDC-maDC_mature|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRAF3 CDH26 MMP25 DGLUCY PLPPR4

1.21e-04156137529b04143f71a0ecc600ac670abd1d521bee55fe7
ToppCellfacs-Marrow-KLS-18m-Myeloid-CD4+_macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300C NCR1 MUL1 KYNU PLTP

1.25e-0415713755d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCellfacs-Marrow-KLS-18m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CD300C NCR1 MUL1 KYNU PLTP

1.25e-041571375ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)--|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP PCDH12 NOS2 DDX4

1.25e-048313743aa95bf2d8ac37e648037faf3d54ebb243a4fde1
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP PCDH12 NOS2 DDX4

1.25e-0483137470804dd63221dd5ed26068ec1b50f11875abbc50
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2-Endothelial_Stalk.Flt1.Lrg1_(Lrg1)|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP PCDH12 NOS2 DDX4

1.25e-04831374c1818411438f53aec76afead5c8caab701b95d39
ToppCellCerebellum-Endothelial-ENDOTHELIAL_STALK-Flt1_2|Cerebellum / BrainAtlas - Mouse McCarroll V32

KCP PCDH12 NOS2 DDX4

1.25e-048313741e7af8aaa20b4c2a77cf2f330113db0faa9d483c
ToppCellLPS-antiTNF-Myeloid-Monocytes,_Macrophages-Neutrophils|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TRAF3 HK3 NAGLU LCP2 KYNU

1.37e-0416013755d8d97c3da5837ba5fe743d2f8438f5cb7cea64b
ToppCellBAL-Mild-cDC_0|Mild / Compartment, Disease Groups and Clusters

MAN1C1 FAM91A1 TMEM255B FZD6 PLXNA2

1.49e-0416313757047d3ba847930f42a6d5f71e18d49f3071c6409
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFI35 GRAMD1B TNRC18 MUL1 HYDIN

1.58e-041651375436ce4bc75e1ba4351c439ccad19f84ad5bcb92f
ToppCellsaliva-Severe-critical_progression_d12-22_with-steroid-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

IFI35 GRAMD1B TNRC18 MUL1 HYDIN

1.58e-041651375242bdb7654f415391fb8e9bdc06412c7eee9c97e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

HK3 GLT1D1 LCP2 MMP25 DDX4

1.62e-0416613756a65dff1333f39ec8c584e6df04b8c1e7f1c8946
ToppCellHealthy_donor-HSPC|World / disease group, cell group and cell class (v2)

HSPG2 OBSL1 MEX3A MEX3B PLTP

1.67e-04167137570630ebdfee8171d625811844f8a7c94736d101e
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THEMIS IQGAP2 DENND1C LCP2 NCR1

1.72e-041681375318fa1bd5a9d6ae95042517ef30515b6416b61e4
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

THEMIS IQGAP2 DENND1C LCP2 NCR1

1.72e-04168137575b3998aff704a77895ee3723813d8a3819b7cec
ToppCelldroplet-Thymus-nan-18m-Myeloid-Macrophage|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STBD1 SPATA19 DBNL ITIH2 CD300C

1.76e-0416913754ac21e8199de4b6917eacadc56fffc6d886ee643
ToppCellPND03-Immune-Immune_Myeloid-Monocytic-Macrophage-iMON-iMON_G2M|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

LIN28B LCP2 KIF24 IFNAR2 TMPO

1.76e-0416913754db49b7eaea34e6558ee73b01e76315e99cc880b
ToppCellwk_08-11-Mesenchymal-Myofibro_&_SMC-Myofibro_2|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

NLRX1 DAB1 MSRA PLPPR4 GLUD2

1.81e-041701375fefb07a7e308b620f946b9ff2b01e1796446fe38
ToppCell5'-Adult-Appendix-Hematopoietic-Myeloid-Monocytes|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

AMPH HK3 GLT1D1 CD300C KYNU

1.81e-0417013751c3c03821c90d41de92fef3278f71093a7fd709c
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_prolif|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FOSB KCP MUL1 QSOX2 PCNT

1.81e-041701375b1a16600754e0c12f7d39c9221f1b03135833f16
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-9|TCGA-Bladder / Sample_Type by Project: Shred V9

ITGAV IFNAR2 FZD6 NFE2L2 SPEN

1.86e-041711375adbcfa4bf6bc1c604535a24435924cdb091e2dd7
ToppCellmild-Others-CD34+_GATA2+_cells|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

PALD1 HSPG2 OBSL1 MEX3A MEX3B

1.92e-041721375379f6f271e653d5e404851e51a189bd582bb0f43
ToppCellCV-Mild-7|Mild / Virus stimulation, Condition and Cluster

EFCAB5 STRN3 USP40 DNAI7 PLTP

1.97e-041731375c9bbca9313a0fdf146c8c995624b94b937e818d8
ToppCelldroplet-Marrow-nan|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 FOSB DBNL MORF4L1 EIF4A2

2.02e-041741375a188ec192c378f731af1c95eb8f1392a2bb18c26
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Lymphocytic-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 IQGAP2 RTEL1 DAB1 MEX3A

2.02e-0417413756987fe7959afce347282f632abc16d800ccab7c4
ToppCell10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-eo/baso/mast-basophil|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

HK3 FOSB TMEM255B ZFY MMP25

2.13e-041761375581d78811b2d99f38a2c7cc268aeb1cf932379c2
ToppCelldroplet-Liver-LIVER_HEP-30m-Myeloid-Kupffer_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HK3 MYO9A PP2D1 DNAI7 SPEN

2.13e-0417613755e46a09a36b9645b1b1fcb0b64bd0898561af3a9
ToppCellcontrol-Others-CD34+_GATA2+_cells|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

HSPG2 STBD1 OBSL1 MEX3A MEX3B

2.25e-0417813752120bd3e099b0b271bf079db9827a2f3eee2f909
ToppCellfacs-Heart-LA-18m-Lymphocytic|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THEMIS DENND1C LCP2 MMP25 KYNU

2.25e-041781375b4b4e021e86d1d523fa40695cb0a91021dee27d1
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CDH26 GK5 FER1L6 MACF1 RAPGEFL1

2.30e-0417913756e965e424eebef50f0202cff75f458be395cfca1
ToppCelldroplet-Tongue-nan-24m-Myeloid-nan|Tongue / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THEMIS IQGAP2 DENND1C LCP2 MTMR7

2.30e-0417913751b079d80f789473701c781f3431ad306e9766797
ToppCell5'-GW_trimst-2-SmallIntestine-Endothelial-blood_vessel_EC-arterial_capillary|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

HSPG2 INHBB PCDH12 FZD6 PLXNA2

2.36e-041801375755050226eeb1991ee7f0d15e39d0458f3e4a791
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 IQGAP2 LCP2 KYNU PLTP

2.55e-041831375a97f052950429245c3231464271e1ba539863bba
ToppCelldroplet-Trachea-nan-3m-Endothelial|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.62e-041841375fa5c3020e75fdde1363393dea97ebd99f1eae9ff
ToppCelldroplet-Trachea-3m-Endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.62e-041841375ad520ab6bb776b5303df505b7e1afb22484f18a7
ToppCellCOVID-19_Convalescent-Myeloid-cDC|COVID-19_Convalescent / Disease group, lineage and cell class

PALD1 FOSB CD300C PKP2 KYNU

2.62e-041841375ad6e910eaebe841a68a5f2f329d43dafc5db158a
ToppCell3'-Adult-LargeIntestine-Hematopoietic-T_cells-ILC3|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

FOSB LCP2 TIPARP MMP25 LRCH4

2.62e-0418413752f9c5887635185dc1c6ec4e959b6d8a28b0bd020
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 FOSB CD300C PKP2 KYNU

2.62e-0418413759d678b24532b7763f2e73f7ccb496259977c5204
ToppCellPBMC-Convalescent-Myeloid-cDC-cDC-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

PALD1 FOSB CD300C PKP2 KYNU

2.62e-041841375383374ad17bd322b8d703a22e475d34ca7b2e6b6
ToppCelldroplet-Marrow-nan-3m|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOSB NSD1 EIF4A2 MACF1 UVRAG

2.62e-0418413751154a5ad7b8512272b7476f949ddac350910bfb7
ToppCellPBMC-Convalescent-Myeloid-cDC|Convalescent / Location, Disease Group, Cell group, Cell class (2021.03.09)

PALD1 FOSB CD300C PKP2 KYNU

2.62e-0418413755535b85b3ad3d0c0392d5884fdc2939c7e1b1c3e
ToppCelldroplet-Trachea-nan-3m-Endothelial-nan|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.62e-0418413751d63cb75a89c5f3f3b9ebf7fce8cb0fd4a92b645
ToppCelldroplet-Trachea-nan-3m-Endothelial-endothelial_cell|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.62e-04184137576caad53d55fff5acca27bf190a6de7b27437d9f
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.62e-0418413751fc1f0a3b4dbb085ebcc3960f67be24a108fe5b9
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.62e-0418413752467207aaea307873ab286f89cfc7668a227a694
ToppCell367C-Lymphocytic-NK_cells-NK_cell_D3|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

EDC3 FOSB TENT5C EIF4A2 MUL1

2.68e-0418513754a5e70ac41e5f3b25a773304ffef3c2a3dd5549d
ToppCellfacs-Limb_Muscle-ForelimbandHindlimb|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TPP2 STRN3 SPAG9 TIPARP LTBP1

2.68e-041851375eb7d3c1363d5fedc611f9c1a91ea823de251355e
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 IQGAP2 MAPT DAB1 LRRTM2

2.82e-04187137516e55d802fc4e71878305e61ad03806aabd59537
ToppCellmetastatic_Lymph_Node-Endothelial_cells-Tumor_ECs|metastatic_Lymph_Node / Location, Cell class and cell subclass

HSPG2 MAN1C1 POLR3B ASXL3 PLXNA2

2.82e-0418713752713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCellPCW_10-12-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

DAB1 PRAG1 PLPPR4 LTBP1 PLXNA2

2.82e-041871375387cb27c8a20031cd87381a9e1172f1f62e1488b
ToppCell15-Trachea-Epithelial-Secretory_progenitor|Trachea / Age, Tissue, Lineage and Cell class

FOSB TENT5C ITIH2 KLK13 KYNU

2.82e-041871375be9fce9e74b2f170a2067f1b31d802912a578329
ToppCellEntopeduncular-Endothelial|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PALD1 HSPG2 PARP14 IFI35 TRIP10

2.89e-04188137594774652fd42bad5012356672ffac8b6d2c22d37
ToppCellPCW_13-14-Mesenchymal-Mesenchymal_myocytic-mes_immature_ASM2_(12)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

DAB1 PRAG1 PLPPR4 LTBP1 PLXNA2

2.96e-0418913750abc7a4900cc9033bc1be69b770ccc54a6bf41b4
ToppCelldroplet-Trachea-3m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l10|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

INHBB PCDH12 PARP14 TMEM255B PLXNA2

2.96e-04189137528b9e96a5206b7fdae9b17daf05c8f5d24b6c5ec
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THEMIS IQGAP2 DENND1C LCP2 NCR1

3.03e-0419013754a75457652d85874d5c6a41648f8003572008b15
ToppCellFetal_29-31_weeks-Immune-monocyte-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

HK3 IQGAP2 GLT1D1 LCP2 KYNU

3.03e-041901375ad297172a74a80ed5c10f921e15efd1da0fd2d6b
ToppCellControl-Myeloid-Transitioning_MDM|Control / group, cell type (main and fine annotations)

IQGAP2 GLT1D1 LCP2 KYNU PLTP

3.03e-041901375d6fd8c23cde4a10cc1517b6899a5a855fdfff2e2
ToppCelldroplet-Limb_Muscle-MUSCLE-30m-Macroglial-Schwann_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CHL1 MAPT DAB1 LRRTM2 RAPGEFL1

3.03e-041901375ff3dec5b45c6ea9b5319fb51a0198c6773b7be26
ToppCellfacs-GAT-Fat-3m|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FOSB APLP2 TIPARP EIF4A2 GLUD1

3.03e-0419013751d92be1b41cff59e834a9d28868f554bd1f3e471
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Lymphocytic_T/NK-Natural_Killer_Cell_/_Natural_Killer_T_Cell-|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

THEMIS IQGAP2 DENND1C LCP2 NCR1

3.03e-041901375cda6173634531240e0bab8766231a150ff8d0129
ToppCellPCW_10-12-Endothelial-Endothelial_immature-endo_immature_arterial2_(6)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

CHL1 HSPG2 PCDH12 TMEM255B FZD6

3.03e-0419013757ba2be2630183df86de21689289a8620a4cd507e
Drug1-pheg

GLUD1 GLUD2 PCNT

2.07e-0651363CID000152041
Diseasehepatic encephalopathy (biomarker_via_orthology)

GLUD1 GLUD2 NOS2

3.74e-05151313DOID:13413 (biomarker_via_orthology)
DiseaseLeukodystrophy, Hypomyelinating, with Hypodontia and Hypogonadotropic Hypogonadism

POLR1C POLR3B

5.85e-0531312C2676243
DiseasePOLR3-related leukodystrophy

POLR1C POLR3B

5.85e-0531312cv:C5679947
Diseasefascioliasis (biomarker_via_orthology)

GLUD1 GLUD2

5.85e-0531312DOID:885 (biomarker_via_orthology)
DiseaseHETE measurement

C16orf82 PIEZO1 FAM91A1 FER1L6

1.70e-04621314EFO_0801166
Diseasechildhood absence epilepsy (biomarker_via_orthology)

GLUD1 GLUD2

2.90e-0461312DOID:1825 (biomarker_via_orthology)
Diseaselimb-girdle muscular dystrophy (implicated_via_orthology)

FER1L6 FER1L4

4.05e-0471312DOID:11724 (implicated_via_orthology)
Diseaseage at initiation of corrective lens use

TBC1D5 POLR3B

5.38e-0481312EFO_0021781
DiseaseParkinson disease

CHL1 SPATA19 MAPT TBC1D5 NAGLU POLR3B ASXL3

5.96e-043211317MONDO_0005180
Diseaseglioblastoma multiforme

RTEL1 POLR3B

6.90e-0491312EFO_0000519
DiseaseHepatic Insufficiency

NFE2L2 NOS2

6.90e-0491312C1306571
Diseasefatty acid measurement

AMPH IFI35 PRAG1 MSRA MACF1 UVRAG MAP4K2 PLTP

7.58e-044361318EFO_0005110
Diseaselate onset Parkinson's disease (is_implicated_in)

MAPT GLUD2

1.05e-03111312DOID:0060892 (is_implicated_in)
DiseasePathological accumulation of air in tissues

NFE2L2 NOS2

1.25e-03121312C0013990
DiseasePARKINSON DISEASE, LATE-ONSET

MAPT GLUD2

1.25e-03121312C3160718
Diseasedementia (is_implicated_in)

MAPT NOS2

1.25e-03121312DOID:1307 (is_implicated_in)
DiseaseEpilepsy

FOSB PCDH12 ASXL3 GLUD1

1.44e-031091314C0014544
Diseasehyperglycemia (is_marker_for)

HSPG2 ITGAV

1.48e-03131312DOID:4195 (is_marker_for)
DiseaseAlzheimer's disease (implicated_via_orthology)

MAPT APLP2 NOS2

2.10e-03571313DOID:10652 (implicated_via_orthology)
Disease2-hydroxyglutarate measurement

DGLUCY PCNT

2.25e-03161312EFO_0021506
Diseasetriacylglycerol 48:1 measurement

C16orf82 SPAG9

2.55e-03171312EFO_0010404
Diseaseresponse to vaccine, cytokine measurement

THEMIS DAB1 MEX3C LTBP1

2.81e-031311314EFO_0004645, EFO_0004873
Diseasecerebral microbleeds

HSPG2 AMPH

3.18e-03191312EFO_0010059
Diseasecumulative dose response to bevacizumab

MSRA GRAMD1B

3.18e-03191312EFO_0005944
Diseaseesterified cholesterol measurement, high density lipoprotein cholesterol measurement

OBSL1 PLTP

3.18e-03191312EFO_0004612, EFO_0008589
Diseasetriglyceride measurement, very low density lipoprotein cholesterol measurement

IFI35 MSRA MACF1 MAP4K2 PLTP

3.31e-032241315EFO_0004530, EFO_0008317
DiseaseProfound Mental Retardation

CHL1 NAGLU NSD1 POLR3B

3.48e-031391314C0020796
DiseaseMental Retardation, Psychosocial

CHL1 NAGLU NSD1 POLR3B

3.48e-031391314C0025363
DiseaseMental deficiency

CHL1 NAGLU NSD1 POLR3B

3.48e-031391314C0917816
Diseaserespiratory system disease

THEMIS RTEL1 UVRAG RAPGEFL1

4.05e-031451314EFO_0000684
Diseaseleucine measurement

C16orf82 PRAG1 PKP2

4.24e-03731313EFO_0009770
DiseaseSplenomegaly

MAPT NFE2L2

4.26e-03221312C0038002

Protein segments in the cluster

PeptideGeneStartEntry
VEVSGHDAPPAILTF

DDX4

276

Q9NQI0
PGETAHVRVPFVNVQ

CPA2

61

P48052
DVEREPPSPAVQHFT

DENND1C

56

Q8IV53
SPVTTPTDEDVGHRI

GRAMD1B

581

Q3KR37
VISRPEPVANEGIDH

ASXL3

1521

Q9C0F0
AGHVPEAVTRVFPQV

NAGLU

246

P54802
PSVVIEPASNHEEEG

AMPH

541

P49418
HDPIVEVEVSVFPAG

CD300C

121

Q08708
VQEGRDEFPEHRTPS

NSD1

1196

Q96L73
PEEAEHGTFVGRIAQ

PCDHA9

36

Q9Y5H5
GHVFSRSLPEVPETI

HSPG2

4216

P98160
PPEVSHGDRDTQSVR

QSOX2

596

Q6ZRP7
PERVVPIQDHSFPSE

TIPARP

131

Q7Z3E1
HVNGNRTVEPFPEGT

MSRA

51

Q9UJ68
FDSVIARGHTEPDPT

PARP3

466

Q9Y6F1
HIQGFPEVGEEELVS

PALD1

681

Q9ULE6
PSEHFALDVIVGPDE

PCDH12

176

Q9NPG4
AGEQVREVVHSIPHP

KLK13

96

Q9UKR3
EHVFTDPLGVQIPED

SPAG9

916

O60271
PVQIDFIDSHVPGED

LRCH4

351

O75427
GPAERTPSEIQFHQV

MAP4K2

321

Q12851
THEDIVALFPVPEGA

MORF4L1

66

Q9UBU8
VRVSSEESEEIPPFH

APLP2

586

Q06481
VVDGPTPHQTVRLEA

NOS2

791

P35228
FFGVTVQDPPVHIVD

OBSL1

796

O75147
TFHEVDSPQGQEPDI

MMP25

156

Q9NPA2
FEPEDTGQRVPVSHS

KLK2

81

P20151
HVVEQVQELDPGSPF

KIAA0100

986

Q14667
HEGSPVKPVAIREFQ

LRCH3

416

Q96II8
AGIAVTTEEHFPEPD

LRRTM2

401

O43300
VQAEFPLGPVTTAHR

NCR1

171

O76036
AVPLPEHGVSVVFVN

MCEE

76

Q96PE7
VDNHPFAGDVVFPRE

CHL1

371

O00533
VPDTFEGHFDGVPVI

ITIH2

226

P19823
TATHVIFVENSPDPR

MTMR7

31

Q9Y216
VGSRTPVEASHPVEN

GOLGA5

86

Q8TBA6
DPGEESHRPFVVVQA

INHBB

266

P09529
GETVHVPFPFDETEL

FAM91A1

611

Q658Y4
PGFGIQLVPEHVETR

FER1L4

1436

A9Z1Z3
REGSPLDIPVDVFVH

LIN28B

51

Q6ZN17
IPLPEGINFVHEVVT

PLTP

436

P55058
GPVPVSVSVDRAHVD

PLXNA2

1016

O75051
VFRGHTQQDPEVPKS

IFI35

51

P80217
FSREHGPGVAEPEVA

LTBP1

786

Q14766
DIPGHIESPVFIATN

NFE2L2

146

Q16236
RHSGLVNVPEEPIEE

NCBP3

331

Q53F19
HVAVPGSPDQRDTVT

KIF24

991

Q5T7B8
TNTVPFDLVPHEDGV

MUL1

121

Q969V5
EHFRIDGPVISESTP

TMPO

266

P42167
SIDPPVHEVEQGIDA

EDC3

441

Q96F86
GPTFALDTVHVDPVI

NLRX1

101

Q86UT6
TGIEGHRVEPRSQEF

HK3

111

P52790
TPEQRGIFTISDHPA

PCNT

191

O95613
IEGEPAPDHRHVQET

MACF1

4071

Q9UPN3
PIFLPEVTIGAHQTD

NDUFA10

311

O95299
PPEFEIVGFTNHINV

IFNAR2

136

P48551
FTHSEVQVLGDPFPV

FOSB

281

P53539
TVQLPATPDEIDHVF

PARP14

86

Q460N5
REAHPFPGQEITETV

FRG2B

256

Q96QU4
REAHPFPGQEITETV

FRG2

256

Q64ET8
ETVPVTFDPHTEFLG

FZD6

131

O60353
SFTVVDEGKPIHVPQ

EFCAB5

1066

A4FU69
PVENVSDPVTVHFEV

CHRNA6

51

Q15825
EISLDQEHIPFGPVV

HYDIN

4526

Q4G0P3
EPVVISEAPSQARGH

BNIP5

506

P0C671
IVFEAGHEPIRDPET

DAB1

201

O75553
GEGDTEVFPTQHVVR

GBA2

766

Q9HCG7
NVHLVIVGPEVDPVF

GLT1D1

196

Q96MS3
SAIEQTHPERVPAGT

ENTR1

191

Q96C92
HGGTIPIVPTAEFQD

GLUD1

481

P00367
PETEEDVGPVVQHIY

ITGAV

796

P06756
DVTRFLNEHPGGEEV

CYB5B

51

O43169
AFPPIEVTLEVHENV

DNAI7

431

Q6TDU7
EAPHIVVGTPGRVFD

EIF4A2

151

Q14240
VAEIAGHAPAREQEP

MAN1C1

66

Q9NR34
GVVITVEPIDRESPH

CDH26

446

Q8IXH8
PPVRDTSHNFGSVDE

GK5

246

Q6ZS86
GDPQTPRFDHLVAIE

DGLUCY

421

Q7Z3D6
PGVSFQPESEVLVHI

C1orf127

91

Q8N9H9
TQPETHFGREPAAAI

DBNL

291

Q9UJU6
HGGTIPIVPTAEFQD

GLUD2

481

P49448
PVPSSEHVAEIVGRQ

MEX3B

71

Q6ZN04
TEALQEEPSHQEGPR

FER1L6

31

Q2WGJ9
VSHPEEPVAGAQTDR

RTEL1

881

Q9NZ71
PDVPVGDESQARVLH

SARS2

176

Q9NP81
EEGEVGTLHPVFARV

SZT2

2511

Q5T011
ETTEPDRIQFVEGPV

SYNC

111

Q9H7C4
VQLPGEFHPVSEAEL

UVRAG

611

Q9P2Y5
HEGARAEEAEPITFP

STRN3

406

Q13033
DGVFAAQHIEPRPLT

TMEM255B

106

Q8WV15
GETVHVPFPFDETEL

LINC00869

256

P0C866
PRDEVQEVVFVPAGT

SCRN2

36

Q96FV2
AVDHINAVIPEGDPE

IQGAP2

306

Q13576
EVFVDGESFSHPRDP

KCP

551

Q6ZWJ8
VPVPSSEHVAEIVGR

MEX3C

236

Q5U5Q3
PEVDVGVVHFTPLIQ

TFB1M

221

Q8WVM0
VEPPEHRSFLSEDGV

RNASE9

186

P60153
QADLFPEGTIRPVHD

POLR1C

181

O15160
ADPRTVGHSVVSPQD

PMM1

231

Q92871
EHSVETPLVRADPFQ

SGCG

176

Q13326
EVVPIHGRGNFPTLE

TENT5C

31

Q5VWP2
ERFTHLPEAGGPEVT

ACVR2B

111

Q13705
VVTEDFSHLPPEQQR

TRIP10

386

Q15642
PPTHGQDIHVTRDVV

SPATA19

76

Q7Z5L4
EPSGIVRVEAHPENN

PLPPR4

616

Q7Z2D5
EHRVVAPTFVPSVEA

TNRC18

366

O15417
FPIVTEVIEAPEGNH

THEMIS

281

Q8N1K5
LHTDRSAGTPVFVPE

TRAF3

21

Q13114
PGSQVPLEVTFHVRA

nan

76

Q6ZSR3
PHVTAVSEQPRAADG

SPEN

3201

Q96T58
SREHVPSGQFPDTEA

STBD1

111

O95210
PVFTLVDADPHGIEI

SPO11

271

Q9Y5K1
VPVPTSEHVAEIVGR

MEX3A

136

A1L020
GSSDDRQIVDTPPHV

RBM17

61

Q96I25
GTIPELPTFHTEVAE

WASH2P

276

Q6VEQ5
GTIPELPTFHTEVAE

WASHC1

276

A8K0Z3
DHGVGIEPVFPENTE

TPP2

546

P29144
AQPHTEIPEGTTAEE

MAPT

91

P10636
EQHSLPVFTVEGLEP

ROS1

996

P08922
DVEESFNVTRPVSPH

POLR3B

86

Q9NW08
GERNIAFHPVSFPEE

PRAG1

171

Q86YV5
DPLRGHVDQFEEQSP

ZNF236

856

Q9UL36
HIQVEARVGPTDGTP

PIEZO1

1841

Q92508
VHLAPPSEEFEVGSI

PLAAT5

156

Q96KN8
SETRHPLQPEEQEVG

TBC1D5

6

Q92609
IQVSPGDTEIHRVEP

RAPGEFL1

411

Q9UHV5
STQVPPELFENEHVR

TBC1D19

216

Q8N5T2
ESHVSSVQHPRPEEG

C16orf82

131

Q7Z2V1
IESPHVFPANAEVGT

USP40

661

Q9NVE5
HLVENDFVGGRSPVP

PKP2

91

Q99959
HVSVPEFVTQLIDDP

UBQLN3

161

Q9H347
GQVAEDRFPESHLPI

TLE6

316

Q9H808
VAPEHTERSVPQDPD

ZKSCAN5

281

Q9Y2L8
TVHNFVPDDPDSVVI

ZFY

51

P08048
NPENVETFPAETTHR

PP2D1

546

A8MPX8
EGPSQEHSRPFSVEA

GARIN5B

681

Q8N5Q1
SVEPVQGETREGSPH

GOLGA8CP

546

A6NN73
PQVPRFPEETESHEE

LCP2

86

Q13094
PVVNIITPSHVEERG

KYNU

386

Q16719
EVSPLFAGTDVIPAH

MYO9A

1781

B2RTY4