Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	extracellular matrix structural constituent	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2 HMCN2 MUC5AC	4.72e-05	188	137	8	GO:0005201
GeneOntologyMolecularFunction	axon guidance receptor activity	PTK7 HMCN2 PALLD	8.59e-05	13	137	3	GO:0008046
GeneOntologyCellularComponent	laminin-11 complex	LAMA5 LAMB2	1.27e-04	3	137	2	GO:0043260
MousePheno	abnormal muscle fiber morphology	COL6A3 XIRP1 FAM120B SGCG POLG OBSCN MAML1 LAMA2 SIRT7 KLHL31 ADAMTS10 TLN2 PMM2	8.64e-06	406	103	13	MP:0004087
MousePheno	abnormal lung development	ZSWIM8 GAK LFNG PTK7 IGF2R KCNJ13 STK40 EPAS1	9.81e-06	142	103	8	MP:0001176
MousePheno	skeletal muscle interstitial fibrosis	COL6A3 SGCG LAMA2	1.33e-05	7	103	3	MP:0003851
MousePheno	abnormal skeletal muscle morphology	CDKN1C COL6A3 PSG5 SGCG POLG OBSCN MAML1 LAMA2 LFNG KLHL31 ADAMTS10 SSPN IGFBP3 TLN2	2.07e-05	508	103	14	MP:0000759
MousePheno	abnormal respiratory system development	ZSWIM8 GAK LFNG PTK7 IGF2R KCNJ13 STK40 EPAS1	2.34e-05	160	103	8	MP:0003115
MousePheno	abnormal heart ventricle wall thickness	ZSWIM8 SGCG SPEG ARHGEF17 IGF2R IGFBP3 EPAS1 SMAD7 PMM2	4.48e-05	227	103	9	MP:0020135
MousePheno	abnormal heart ventricle morphology	ZSWIM8 SEMA3C XIRP1 FAM120B SGCG SPEG POLG LAMA5 ARHGEF17 PTK7 IGF2R HMCN2 IGFBP3 UBE3C EPAS1 SMAD7 PMM2	6.34e-05	793	103	17	MP:0005294
MousePheno	dystrophic muscle	SGCG MAML1 LAMA2 TLN2	8.53e-05	32	103	4	MP:0000752
MousePheno	abnormal muscle morphology	CDKN1C COL6A3 XIRP1 FAM120B PSG5 SGCG POLG OBSCN MAML1 LAMA2 SIRT7 LFNG KLHL31 ADAMTS10 SSPN IGF2R IGFBP3 TLN2 SMAD7 PMM2	1.42e-04	1106	103	20	MP:0002108
MousePheno	abnormal skeletal muscle fiber morphology	COL6A3 SGCG OBSCN MAML1 LAMA2 KLHL31 ADAMTS10 TLN2	1.70e-04	212	103	8	MP:0003084
MousePheno	abnormal muscle physiology	COL6A3 XIRP1 FAM120B DSCAM PSG5 SGCG SPEG OBSCN LAMA2 SIRT7 GFRA2 KLHL31 ARFGEF3 SSPN PCDH15 UBE3C SMAD7 PMM2	1.91e-04	954	103	18	MP:0002106
Domain	Ig_I-set	SEMA3C DSCAM SPEG OBSCN PTK7 HMCN2 PTPRD PTPRK SIGLEC1 PALLD	1.40e-06	190	137	10	IPR013098
Domain	I-set	SEMA3C DSCAM SPEG OBSCN PTK7 HMCN2 PTPRD PTPRK SIGLEC1 PALLD	1.40e-06	190	137	10	PF07679
Domain	IGc2	DSCAM PSG5 SPEG OBSCN PTK7 HMCN2 PTPRD SIGLEC1 PALLD	6.02e-05	235	137	9	SM00408
Domain	Ig_sub2	DSCAM PSG5 SPEG OBSCN PTK7 HMCN2 PTPRD SIGLEC1 PALLD	6.02e-05	235	137	9	IPR003598
Domain	IG	SEMA3C DSCAM PSG5 SPEG OBSCN PTK7 HMCN2 PTPRD PTPRK VSTM2L SIGLEC1 PALLD	6.46e-05	421	137	12	SM00409
Domain	Ig_sub	SEMA3C DSCAM PSG5 SPEG OBSCN PTK7 HMCN2 PTPRD PTPRK VSTM2L SIGLEC1 PALLD	6.46e-05	421	137	12	IPR003599
Domain	Laminin_N	LAMA2 LAMA5 LAMB2	2.02e-04	16	137	3	IPR008211
Domain	LamNT	LAMA2 LAMA5 LAMB2	2.02e-04	16	137	3	SM00136
Domain	LAMININ_NTER	LAMA2 LAMA5 LAMB2	2.02e-04	16	137	3	PS51117
Domain	Laminin_N	LAMA2 LAMA5 LAMB2	2.02e-04	16	137	3	PF00055
Domain	Ig-like_fold	COL6A3 SEMA3C DSCAM PSG5 NXPE4 SPEG OBSCN TGM5 PTK7 HMCN2 PTPRD PTPRK VSTM2L SIGLEC1 PALLD	2.14e-04	706	137	15	IPR013783
Domain	IG_LIKE	SEMA3C DSCAM PSG5 SPEG OBSCN PTK7 HMCN2 PTPRD PTPRK VSTM2L SIGLEC1 PALLD	2.71e-04	491	137	12	PS50835
Domain	Ig-like_dom	SEMA3C DSCAM PSG5 SPEG OBSCN PTK7 HMCN2 PTPRD PTPRK VSTM2L SIGLEC1 PALLD	3.37e-04	503	137	12	IPR007110
Domain	-	COL6A3 SEMA3C DSCAM PSG5 NXPE4 SPEG OBSCN TGM5 PTK7 PTPRD PTPRK VSTM2L SIGLEC1 PALLD	3.73e-04	663	137	14	2.60.40.10
Domain	ig	DSCAM PSG5 OBSCN PTPRD PTPRK VSTM2L SIGLEC1	5.10e-04	190	137	7	PF00047
Domain	Immunoglobulin	DSCAM PSG5 OBSCN PTPRD PTPRK VSTM2L SIGLEC1	5.10e-04	190	137	7	IPR013151
Domain	Laminin_domII	LAMA2 LAMA5	5.26e-04	5	137	2	IPR010307
Domain	Laminin_aI	LAMA2 LAMA5	5.26e-04	5	137	2	IPR009254
Domain	Laminin_I	LAMA2 LAMA5	5.26e-04	5	137	2	PF06008
Domain	Laminin_II	LAMA2 LAMA5	5.26e-04	5	137	2	PF06009
Domain	PAS	ARNT PDE8B EPAS1	7.89e-04	25	137	3	PF00989
Domain	PAS_fold	ARNT PDE8B EPAS1	7.89e-04	25	137	3	IPR013767
Domain	Cupin_4	JMJD8 KDM8	1.09e-03	7	137	2	PF08007
Pathway	REACTOME_ECM_PROTEOGLYCANS	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2	1.27e-05	76	96	6	M27219
Pathway	REACTOME_LAMININ_INTERACTIONS	COL4A3 LAMA2 LAMA5 LAMB2	4.83e-05	30	96	4	M27216
Pathway	PID_INTEGRIN4_PATHWAY	LAMA2 LAMA5 LAMB2	4.85e-05	11	96	3	M158
Pathway	PID_INTEGRIN1_PATHWAY	COL4A3 COL6A3 LAMA2 LAMA5 LAMB2	8.49e-05	66	96	5	M18
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	CDKN1C COL4A3 LAMA5 LAMB2 PLCG1	1.29e-04	72	96	5	M39403
Pathway	WP_PRIMARY_FOCAL_SEGMENTAL_GLOMERULOSCLEROSIS_FSGS	CDKN1C COL4A3 LAMA5 LAMB2 PLCG1	1.37e-04	73	96	5	MM15906
Pathway	REACTOME_MET_PROMOTES_CELL_MOTILITY	LAMA2 LAMA5 LAMB2 DOCK7	1.69e-04	41	96	4	M27778
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A3 COL6A3 COL6A6 GFRA2	1.85e-04	42	96	4	M7169
Pathway	WP_NEPHROTIC_SYNDROME	COL4A3 LAMB2 GPC5 PMM2	2.43e-04	45	96	4	M39864
Pathway	KEGG_ECM_RECEPTOR_INTERACTION	COL6A3 COL6A6 LAMA2 LAMA5 LAMB2	2.66e-04	84	96	5	M7098
Pathway	REACTOME_NCAM1_INTERACTIONS	COL4A3 COL6A3 COL6A6	3.21e-04	20	96	3	MM15061
Pathway	REACTOME_DISEASES_OF_GLYCOSYLATION	LFNG ADAMTS10 ADAMTS9 GPC5 MUC5AC PMM2	4.30e-04	143	96	6	M27275
Pathway	WP_SMALL_CELL_LUNG_CANCER	CDKN1C COL4A3 LAMA2 LAMA5 LAMB2	4.94e-04	96	96	5	M39834
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A3 COL6A3 COL6A6 PLCG1	6.05e-04	57	96	4	MM14713
Pathway	REACTOME_SIGNALING_BY_PDGF	COL4A3 COL6A3 COL6A6 PLCG1	6.47e-04	58	96	4	M2049
Pathway	REACTOME_REGULATION_OF_GENE_EXPRESSION_BY_HYPOXIA_INDUCIBLE_FACTOR	ARNT EPAS1	6.76e-04	6	96	2	MM14521
Pathway	REACTOME_NON_INTEGRIN_MEMBRANE_ECM_INTERACTIONS	COL4A3 LAMA2 LAMA5 LAMB2	6.90e-04	59	96	4	M27218
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	EPPK1 SPEG POLG HECTD4 OBSCN MAML1 LAMA5 SLCO4A1 LAMB2 CARD10 MYORG ESRP2 IGF2R MROH1 DNAJC14 TLN2 UNKL PLCG1 STK40 UBE3C SMAD7	4.33e-09	1105	141	21	35748872
Pubmed	Expression of the immunoglobulin superfamily cell adhesion molecules in the developing spinal cord and dorsal root ganglion.	DSCAM PSG5 SPEG OBSCN PTK7 PTPRD PTPRK SIGLEC1	3.49e-07	162	141	8	25826454
Pubmed	A synaptic nidogen: developmental regulation and role of nidogen-2 at the neuromuscular junction.	LAMA2 LAMA5 LAMB2	1.29e-06	6	141	3	18817539
Pubmed	Interaction of the PAS B domain with HSP90 accelerates hypoxia-inducible factor-1alpha stabilization.	ARNT HSPA4 EPAS1	2.26e-06	7	141	3	15319539
Pubmed	Laminin isoforms in fetal and adult human adrenal cortex.	LAMA2 LAMA5 LAMB2	2.26e-06	7	141	3	14557481
Pubmed	Cannabinoid inhibits HIV-1 Tat-stimulated adhesion of human monocyte-like cells to extracellular matrix proteins.	COL4A3 LAMA2 LAMA5 LAMB2	3.61e-06	26	141	4	24742657
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	PCYT1A ZSWIM8 DSCAM POLG POLR2C HECTD4 DEF8 PTPN13 PPP2R5E PTPRD DNAJC14 PTPRK ADAMTS9 RNF10 TLN2 PLCG1 UQCRC1 SEZ6L	4.87e-06	1285	141	18	35914814
Pubmed	Proteomics analysis of cardiac extracellular matrix remodeling in a porcine model of ischemia/reperfusion injury.	COL6A3 LAMA2 LAMB2 ADAMTS9 FRZB	6.42e-06	64	141	5	22261194
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	SPEG ARHGEF17 ARFGEF3 PPP2R5E MROH1 STARD9 DOCK7 UBE3C CAMSAP2 SEZ6L	6.83e-06	407	141	10	12693553
Pubmed	Distribution of the ten known laminin chains in the pathways and targets of developing sensory axons.	LAMA2 LAMA5 LAMB2	7.67e-06	10	141	3	9034910
Pubmed	Quantitative proteomic profiling of the extracellular matrix of pancreatic islets during the angiogenic switch and insulinoma progression.	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2 HMCN2	7.76e-06	175	141	7	28071719
Pubmed	Mutations in LAMB1 cause cobblestone brain malformation without muscular or ocular abnormalities.	LAMA2 LAMA5 LAMB2	1.05e-05	11	141	3	23472759
Pubmed	Regional differences in the expression of laminin isoforms during mouse neural tube development.	LAMA2 LAMA5 LAMB2	1.05e-05	11	141	3	21524702
Pubmed	Large-scale identification of genes implicated in kidney glomerulus development and function.	CDKN1C COL4A3 LAMA2 LAMA5	1.09e-05	34	141	4	16498405
Pubmed	Wnt5a Deficiency Leads to Anomalies in Ureteric Tree Development, Tubular Epithelial Cell Organization and Basement Membrane Integrity Pointing to a Role in Kidney Collecting Duct Patterning.	COL4A3 LAMA2 LAMB2	1.40e-05	12	141	3	26794322
Pubmed	Distribution and function of laminins in the neuromuscular system of developing, adult, and mutant mice.	LAMA2 LAMA5 LAMB2	1.40e-05	12	141	3	9396756
Pubmed	Endothelial PAS domain protein 1 gene promotes angiogenesis through the transactivation of both vascular endothelial growth factor and its receptor, Flt-1.	ARNT EPAS1	1.63e-05	2	141	2	15192019
Pubmed	Structural basis of ARNT PAS-B dimerization: use of a common beta-sheet interface for hetero- and homodimerization.	ARNT EPAS1	1.63e-05	2	141	2	16181639
Pubmed	The expression pattern of laminin isoforms in Hirschsprung disease reveals a distal peripheral nerve differentiation.	LAMA2 LAMA5	1.63e-05	2	141	2	16226104
Pubmed	Expression of secreted frizzled related proteins 3 and 4 in human ventricular myocardium correlates with apoptosis related gene expression.	SFRP4 FRZB	1.63e-05	2	141	2	10728394
Pubmed	COL6A and LAMA2 Mutation Congenital Muscular Dystrophy: A Clinical and Electrophysiological Study.	COL6A3 LAMA2	1.63e-05	2	141	2	29465610
Pubmed	Transcriptional activity of the promoter region of rat frizzled-related protein gene.	SFRP4 FRZB	1.63e-05	2	141	2	11485313
Pubmed	Phenotypic suppression of acral peeling skin syndrome in a patient with autosomal recessive congenital ichthyosis.	TGM5 ALOXE3	1.63e-05	2	141	2	32618001
Pubmed	Ribonucleic acid polymerase II binding subunit 3 (Rpb3), a potential nuclear target of insulin-like growth factor binding protein-3.	POLR2C IGFBP3	1.63e-05	2	141	2	16455777
Pubmed	Association between polymorphisms in sclerostin, dickkopfs and secreted frizzled-related protein genes and bone mineral density in postmenopausal Korean women.	SFRP4 FRZB	1.63e-05	2	141	2	24662300
Pubmed	Allosteric inhibition of hypoxia inducible factor-2 with small molecules.	ARNT EPAS1	1.63e-05	2	141	2	23434853
Pubmed	Orthologous relationship of obscurin and Unc-89: phylogeny of a novel family of tandem myosin light chain kinases.	SPEG OBSCN	1.63e-05	2	141	2	15185077
Pubmed	Artificial ligand binding within the HIF2alpha PAS-B domain of the HIF2 transcription factor.	ARNT EPAS1	1.63e-05	2	141	2	19129502
Pubmed	Intraspecific mating with CzechII/Ei mice rescue lethality associated with loss of function mutations of the imprinted genes, Igf2r and Cdkn1c.	CDKN1C IGF2R	1.63e-05	2	141	2	15475262
Pubmed	Dual oxidase 1-dependent MUC5AC mucin expression in cultured human airway epithelial cells.	DUOX1 MUC5AC	1.63e-05	2	141	2	15640347
Pubmed	Exploring the predictive values of SERP4 and FRZB in dilated cardiomyopathy based on an integrated analysis.	SFRP4 FRZB	1.63e-05	2	141	2	39425025
Pubmed	Biallelic variants in HECT E3 paralogs, HECTD4 and UBE3C, encoding ubiquitin ligases cause neurodevelopmental disorders that overlap with Angelman syndrome.	HECTD4 UBE3C	1.63e-05	2	141	2	36401616
Pubmed	The extracellular matrix controls stem cell specification and crypt morphology in the developing and adult mouse gut.	LAMA2 LAMA5 LAMB2	1.81e-05	13	141	3	36350252
Pubmed	Mesangial cells organize the glomerular capillaries by adhering to the G domain of laminin alpha5 in the glomerular basement membrane.	COL4A3 LAMA5 LAMB2	1.81e-05	13	141	3	12682087
Pubmed	Characterization of the Extracellular Matrix of Normal and Diseased Tissues Using Proteomics.	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2	1.95e-05	135	141	6	28675934
Pubmed	Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.	COL4A3 LAMA2 LAMA5 LAMB2	2.11e-05	40	141	4	27068110
Pubmed	Laminin alpha5 chain is required for intestinal smooth muscle development.	LAMA2 LAMA5 LAMB2	2.86e-05	15	141	3	12921739
Pubmed	Basement membrane composition in the early mouse embryo day 7.	LAMA2 LAMA5 LAMB2	2.86e-05	15	141	3	15895400
Pubmed	Defective glomerulogenesis in the absence of laminin alpha5 demonstrates a developmental role for the kidney glomerular basement membrane.	COL4A3 LAMA2 LAMA5	2.86e-05	15	141	3	10625553
Pubmed	Localization of basement membrane-associated protein isoforms during development of the ocular surface of mouse eye.	COL4A3 LAMA2 LAMA5	2.86e-05	15	141	3	9264260
Pubmed	Laminin alpha5 is necessary for submandibular gland epithelial morphogenesis and influences FGFR expression through beta1 integrin signaling.	LAMA2 LAMA5 LAMB2	3.51e-05	16	141	3	17601529
Pubmed	Extracellular matrix signatures of human primary metastatic colon cancers and their metastases to liver.	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2	3.95e-05	153	141	6	25037231
Pubmed	Prediction of the coding sequences of unidentified human genes. XVI. The complete sequences of 150 new cDNA clones from brain which code for large proteins in vitro.	SPEG CEMIP2 ADAMTS9 STARD9 KCNT1 TECPR1	3.95e-05	153	141	6	10718198
Pubmed	Beta1-integrins are critical for cerebellar granule cell precursor proliferation.	LAMA2 LAMA5 LAMB2	4.25e-05	17	141	3	15056720
Pubmed	Glycoproteomics Reveals Decorin Peptides With Anti-Myostatin Activity in Human Atrial Fibrillation.	COL6A3 COL6A6 LAMA2 LAMA5 LAMB2	4.87e-05	97	141	5	27559042
Pubmed	Increased IGF-II protein affects p57kip2 expression in vivo and in vitro: implications for Beckwith-Wiedemann syndrome.	CDKN1C IGF2R	4.88e-05	3	141	2	10779549
Pubmed	[Effect of osmotic response element binding protein on mucus secretion with hypertonicity in human airway epithelial cells].	MUC5AC HSPA4	4.88e-05	3	141	2	21418859
Pubmed	Hypoxia-inducible factor directs POMC gene to mediate hypothalamic glucose sensing and energy balance regulation.	ARNT EPAS1	4.88e-05	3	141	2	21814490
Pubmed	Hepatic Aryl hydrocarbon Receptor Nuclear Translocator (ARNT) regulates metabolism in mice.	ARNT EPAS1	4.88e-05	3	141	2	29190746
Pubmed	Coiled-coil coactivators play a structural role mediating interactions in hypoxia-inducible factor heterodimerization.	ARNT EPAS1	4.88e-05	3	141	2	25627682
Pubmed	Loss of alpha3/alpha4(IV) collagen from the glomerular basement membrane induces a strain-dependent isoform switch to alpha5alpha6(IV) collagen associated with longer renal survival in Col4a3-/- Alport mice.	COL4A3 LAMB2	4.88e-05	3	141	2	16769745
Pubmed	P. aeruginosa lipopolysaccharide-induced MUC5AC and CLCA3 expression is partly through Duox1 in vitro and in vivo.	DUOX1 MUC5AC	4.88e-05	3	141	2	23691121
Pubmed	Altered DNA binding specificity of Arnt by selection of partner bHLH-PAS proteins.	ARNT EPAS1	4.88e-05	3	141	2	15190133
Pubmed	Sirtuin-7 inhibits the activity of hypoxia-inducible factors.	SIRT7 EPAS1	4.88e-05	3	141	2	23750001
Pubmed	Proteinuria precedes podocyte abnormalities inLamb2-/- mice, implicating the glomerular basement membrane as an albumin barrier.	LAMA5 LAMB2	4.88e-05	3	141	2	16886065
Pubmed	Structural basis for PAS domain heterodimerization in the basic helix--loop--helix-PAS transcription factor hypoxia-inducible factor.	ARNT EPAS1	4.88e-05	3	141	2	14668441
Pubmed	Hyaluronan degradation by HYAL2 is essential for odontoblastic differentiation and migration of mouse dental papilla cells.	CEMIP2 HYAL2	4.88e-05	3	141	2	38490466
Pubmed	A cyclic peptide inhibitor of HIF-1 heterodimerization that inhibits hypoxia signaling in cancer cells.	ARNT EPAS1	4.88e-05	3	141	2	23796364
Pubmed	Developmental expression and cellular origin of the laminin alpha2, alpha4, and alpha5 chains in the intestine.	LAMA2 LAMA5	4.88e-05	3	141	2	10364433
Pubmed	Hypoxia-inducible factors regulate filaggrin expression and epidermal barrier function.	ARNT EPAS1	4.88e-05	3	141	2	24999590
Pubmed	Methylation-mediated silencing of PTPRD induces pulmonary hypertension by promoting pulmonary arterial smooth muscle cell migration via the PDGFRB/PLCγ1 axis.	PTPRD PLCG1	4.88e-05	3	141	2	35848503
Pubmed	The role of laminins in the organization and function of neuromuscular junctions.	LAMA5 LAMB2	4.88e-05	3	141	2	27614294
Pubmed	The aryl hydrocarbon receptor nuclear translocator is an essential regulator of murine hematopoietic stem cell viability.	ARNT EPAS1	4.88e-05	3	141	2	25855602
Pubmed	The HSP70 co-chaperone DNAJC14 targets misfolded pendrin for unconventional protein secretion.	DNAJC14 HSPA4	4.88e-05	3	141	2	27109633
Pubmed	Laminin α2, α4, and α5 Chains Positively Regulate Migration and Survival of Oligodendrocyte Precursor Cells.	LAMA2 LAMA5	4.88e-05	3	141	2	31882770
Pubmed	STK40 inhibits trophoblast fusion by mediating COP1 ubiquitination to degrade P57Kip2.	CDKN1C STK40	4.88e-05	3	141	2	39304928
Pubmed	Structural integration in hypoxia-inducible factors.	ARNT EPAS1	4.88e-05	3	141	2	26245371
Pubmed	KAT8/SIRT7-mediated Fascin-K41 acetylation/deacetylation regulates tumor metastasis in esophageal squamous cell carcinoma.	SIRT7 KAT8	4.88e-05	3	141	2	38411274
Pubmed	Pathogenicity of a Human Laminin β2 Mutation Revealed in Models of Alport Syndrome.	COL4A3 LAMB2	4.88e-05	3	141	2	29263159
Pubmed	Laminin isoforms in development and disease.	LAMA2 LAMB2	4.88e-05	3	141	2	17426950
Pubmed	Laminin-11.	LAMA5 LAMB2	4.88e-05	3	141	2	10481268
Pubmed	Tetratricopeptide repeat domain 3 overexpression tends to form aggregates and inhibit ubiquitination and degradation of DNA polymerase γ.	POLG HSPA4	4.88e-05	3	141	2	29290964
Pubmed	Expression of laminin alpha 1, alpha 5 and beta 2 chains during embryogenesis of the kidney and vasculature.	LAMA5 LAMB2	4.88e-05	3	141	2	9049978
Pubmed	Activity of hypoxia-inducible factor 2alpha is regulated by association with the NF-kappaB essential modulator.	ARNT EPAS1	4.88e-05	3	141	2	15653678
Pubmed	Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells.	ARNT EPAS1	4.88e-05	3	141	2	9000051
Pubmed	Hypoxia-inducible factor-dependent production of profibrotic mediators by hypoxic hepatocytes.	ARNT EPAS1	4.88e-05	3	141	2	19302442
Pubmed	Molecular imaging: into in vivo interaction of HIF-1alpha and HIF-2alpha with ARNT.	ARNT EPAS1	4.88e-05	3	141	2	19845609
Pubmed	Hypoxia-inducible factors in the kidney.	ARNT EPAS1	4.88e-05	3	141	2	16554418
Pubmed	Hypoxia-inducible factor regulates alphavbeta3 integrin cell surface expression.	ARNT EPAS1	4.88e-05	3	141	2	15689487
Pubmed	Amplification of extracellular matrix and oncogenes in tat-transfected human salivary gland cell lines with expression of laminin, fibronectin, collagens I, III, IV, c-myc and p53.	LAMA2 LAMA5 LAMB2	5.09e-05	18	141	3	11311202
Pubmed	Collagen VI suppresses fibronectin-induced enteric neural crest cell migration by downregulation of focal adhesion proteins.	COL6A3 SEMA3C GFRA2	6.03e-05	19	141	3	29196262
Pubmed	The matrisome: in silico definition and in vivo characterization by proteomics of normal and tumor extracellular matrices.	COL6A3 SEMA3C LAMA2 LAMA5 LAMB2 HMCN2	6.43e-05	167	141	6	22159717
Pubmed	Laminin and integrin expression in the ventral ectodermal ridge of the mouse embryo: implications for regulation of BMP signalling.	LAMA2 LAMA5 LAMB2	7.07e-05	20	141	3	22911573
Pubmed	Reciprocal interaction between SIRT6 and APC/C regulates genomic stability.	SEH1L ERCC4 FXR2 POLR2C HECTD4 DNAJC9 NKTR EIF2AK3 HSPA4	8.22e-05	440	141	9	34244565
Pubmed	Developmental potential of mouse primordial germ cells.	CDKN1C IGF2R	9.74e-05	4	141	2	10101117
Pubmed	Laminin α2-mediated focal adhesion kinase activation triggers Alport glomerular pathogenesis.	COL4A3 LAMA2	9.74e-05	4	141	2	24915008
Pubmed	Exome sequencing in seven families and gene-based association studies indicate genetic heterogeneity and suggest possible candidates for fibromuscular dysplasia.	DYNC2H1 OBSCN	9.74e-05	4	141	2	26147384
Pubmed	CNS Neurons Deposit Laminin α5 to Stabilize Synapses.	LAMA5 LAMB2	9.74e-05	4	141	2	29091766
Pubmed	GPC5 suppresses lung cancer progression and metastasis via intracellular CTDSP1/AhR/ARNT signaling axis and extracellular exosome secretion.	ARNT GPC5	9.74e-05	4	141	2	34079082
Pubmed	Hypoxia-induced mitogenic factor has antiapoptotic action and is upregulated in the developing lung: coexpression with hypoxia-inducible factor-2alpha.	ARNT EPAS1	9.74e-05	4	141	2	15117738
Pubmed	Differential effects of secreted frizzled-related proteins (sFRPs) on osteoblastic differentiation of mouse mesenchymal cells and apoptosis of osteoblasts.	SFRP4 FRZB	9.74e-05	4	141	2	18166153
Pubmed	Molecular and genetic characterization of sarcospan: insights into sarcoglycan-sarcospan interactions.	SGCG SSPN	9.74e-05	4	141	2	10942431
Pubmed	Distribution and isolation of four laminin variants; tissue restricted distribution of heterotrimers assembled from five different subunits.	LAMA2 LAMB2	9.74e-05	4	141	2	2099832
Pubmed	The action of HIF-3α variants on HIF-2α-HIF-1β heterodimer formation is directly probed in live cells.	ARNT EPAS1	9.74e-05	4	141	2	26160453
Pubmed	Hypoxia-inducible factors 1alpha and 2alpha regulate trophoblast differentiation.	ARNT EPAS1	9.74e-05	4	141	2	16287860
Pubmed	Laminin compensation in collagen alpha3(IV) knockout (Alport) glomeruli contributes to permeability defects.	COL4A3 LAMA5	9.74e-05	4	141	2	17699809
Pubmed	Laminin-1 reexpression in Alport mouse glomerular basement membranes.	COL4A3 LAMA5	9.74e-05	4	141	2	12631063
Pubmed	Targeting the hypoxia-sensing pathway in clinical hematology.	ARNT EPAS1	9.74e-05	4	141	2	24371328
Pubmed	CREB binding protein is required for both short-term and long-term memory formation.	ARNT EPAS1	9.74e-05	4	141	2	20881124
Pubmed	Epigenetic re-expression of HIF-2α suppresses soft tissue sarcoma growth.	ARNT EPAS1	9.74e-05	4	141	2	26837714
GeneFamily	Blood group antigens\|CD molecules\|I-set domain containing\|Immunoglobulin like domain containing	SEMA3C DSCAM SPEG OBSCN PTK7 HMCN2 PTPRD SIGLEC1 PALLD	2.92e-07	161	101	9	593
GeneFamily	Laminin subunits	LAMA2 LAMA5 LAMB2	3.59e-05	12	101	3	626
GeneFamily	Secreted frizzled-related proteins	SFRP4 FRZB	3.06e-04	5	101	2	733
Coexpression	NABA_BASEMENT_MEMBRANES	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2	6.60e-08	40	139	6	M5887
Coexpression	NABA_MATRISOME	COL4A3 COL6A3 CPAMD8 SEMA3C SFRP4 COL6A6 LAMA2 LAMA5 LAMB2 TGM5 ADAMTS10 HMCN2 IGFBP3 ADAMTS9 FRZB GPC5 ITIH6 MUC5AC HYAL2	2.15e-06	1026	139	19	M5889
Coexpression	GSE24671_CTRL_VS_BAKIMULC_INFECTED_MOUSE_SPLENOCYTES_DN	COL4A3 LAMA2 TSC22D2 SLC7A8 PTPN13 PTPRK PLCG1 EPAS1	3.63e-06	170	139	8	M9445
Coexpression	PEREZ_TP53_TARGETS	CDKN1C GAK EPPK1 HECTD4 OBSCN MAML1 ARHGEF17 MYORG ESRP2 DUOX1 ADO IGFBP3 FRZB UNKL IRF2BPL ABCC12 ASPSCR1 MUC5AC SEC14L5 SMAD7	5.61e-06	1201	139	20	M4391
Coexpression	LAKE_ADULT_KIDNEY_C2_PODOCYTES	CDKN1C COL4A3 DYNC2H1 SLC7A8 PTPN13 PTPRD ADAMTS9 PALLD	1.82e-05	212	139	8	M39221
Coexpression	NABA_MATRISOME	COL4A3 COL6A3 SEMA3C SFRP4 COL6A6 LAMA2 LAMA5 LAMB2 TGM5 ADAMTS10 HMCN2 IGFBP3 ADAMTS9 FRZB GPC5 MUC5AC HYAL2	2.57e-05	1008	139	17	MM17056
Coexpression	FAN_EMBRYONIC_CTX_BRAIN_ENDOTHELIAL_2	EPS8 LAMA2 LAMB2 GRM3 ARHGEF17 PTPRK PDE8B FRZB EPAS1	3.61e-05	303	139	9	M39040
Coexpression	DESCARTES_FETAL_LIVER_MESOTHELIAL_CELLS	COL4A3 CPAMD8 SEMA3C SPEG LAMA5 ARFGEF3 ABCG4 PTPRD PALLD	4.64e-05	313	139	9	M40228
Coexpression	BOQUEST_STEM_CELL_UP	COL6A3 SEMA3C SFRP4 LAMA2 SSPN PTPN13 PTPRD IGFBP3	7.95e-05	261	139	8	M1834
Coexpression	GSE369_SOCS3_KO_VS_IFNG_KO_LIVER_UP	GMEB2 APOBEC4 EFHC2 PTPN13 IGF2R NKTR PALLD	9.59e-05	199	139	7	M5978
Coexpression	GSE42724_B1_BCELL_VS_PLASMABLAST_DN	FAM120B FXR2 DEF8 MAML1 ADAMTS10 EIF2AK3 TECPR1	9.89e-05	200	139	7	M9789
Coexpression	NABA_CORE_MATRISOME	COL4A3 COL6A3 COL6A6 LAMA2 LAMA5 LAMB2 HMCN2 IGFBP3	1.01e-04	270	139	8	MM17057
Coexpression	LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN	ZSWIM8 NSUN4 GAK DYNC2H1 PI4K2A ARHGEF17 DNALI1 ABCG4 DOCK7 DNAJC9 NKTR STK40 ZRANB1 HYAL2	1.03e-04	807	139	14	M14594
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ANO2 CPAMD8 SLCO4A1 CARD10 OR2AJ1 IGFBP3 EPAS1 HYAL2 SMAD7	1.34e-08	196	141	9	915e4a7422058be246b54760df31e8a607310625
ToppCell	Fibroblasts-DKK3+_Fibroblasts\|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues	COL6A3 SEMA3C SFRP4 LAMA2 LAMB2 SSPN HMCN2 PTPRD PALLD	1.46e-08	198	141	9	4f4632f26a2043c5e4ab89031b4229b5dca1bd48
ToppCell	droplet-Limb_Muscle-Pre-Sort\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 SFRP4 SPEG LAMA5 LAMB2 CEMIP2 ADAMTS9 PALLD	1.13e-07	180	141	8	af2bafcd1b2082629de3ea336711add01565c4c4
ToppCell	droplet-Limb_Muscle-Pre-Sort-18m\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	XIRP1 SFRP4 SPEG LAMA5 LAMB2 CEMIP2 ADAMTS9 PALLD	1.13e-07	180	141	8	f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-brain_pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 COL6A3 XIRP1 LAMA5 LAMB2 ARHGEF17 DOCK7 PALLD	1.39e-07	185	141	8	38486b69c48dc5e1c4e1488208fa8954a973eccb
ToppCell	facs-Brain_Non-Myeloid-Striatum-24m-Mesenchymal-Pericyte\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL4A3 COL6A3 XIRP1 LAMA5 LAMB2 ARHGEF17 DOCK7 PALLD	1.39e-07	185	141	8	3c28b5ceba3cfdb6f7e32d5b42e03b6a81a7a658
ToppCell	droplet-Kidney-nan-18m-Epithelial-kidney_mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ANO2 XIRP1 SGCG SPEG LAMB2 SSPN PALLD EPAS1	1.58e-07	188	141	8	d1a4cd4db95d8d32b79156290f7867f32824cc87
ToppCell	COVID-19-Heart\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 SGCG OBSCN LAMA2 TMEM71 KLHL31 ADAMTS9 PALLD	1.71e-07	190	141	8	918ad5037881212008f9f69d5df5da91fd01422c
ToppCell	COVID-19-Heart-Fib_+_EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	COL4A3 EPS8 ANO2 COL6A3 DYNC2H1 LAMA2 PTPN13 EPAS1	1.85e-07	192	141	8	60b1312e84f6d6448365a952469c506c00b5fe93
ToppCell	10x_3'_v2v3-Non-neoplastic-Glial-Neuronal-Oligodendrocyte-Oligodendrocyte-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	CDKN1C SEMA3C GRM3 ARFGEF3 PTPN13 PTPRD PLA2G4C SEC14L5	2.26e-07	197	141	8	82b8e22317cad6d3786bd70d91107007c0ccd7cd
ToppCell	wk_20-22-Mesenchymal-Myofibro_&_SMC-Pericyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	EPS8 COL6A3 LAMA2 ARHGEF17 IGFBP3 ADAMTS9 FRZB MCTP2	2.26e-07	197	141	8	44cd1ece3633a31e8c9b667cd3cbc2749c06f478
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 COL6A6 SGCG LAMA2 PTPRD FRZB PCDH15 PALLD	2.26e-07	197	141	8	13896ec65ccda0b928c91d41112dc01b480036b7
ToppCell	Smart-start-Cell-Wel_seq-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia/MHC-F\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FAM120B SFRP4 LAMA5 LAMB2 ARHGEF17 SLC7A8 ADAMTS9 JMJD8	2.34e-07	198	141	8	399760b6b6fef8639ded53b14f251b9fce600e81
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	COL6A3 SEMA3C SFRP4 LAMA2 PTK7 SSPN MCTP2 PALLD	2.53e-07	200	141	8	09537dc25f8b8b4654a7c183827ee1522a41a4e0
ToppCell	Parenchymal-10x3prime_v2-Stromal-Fibroblastic-Fibro_myofibroblast\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	EPS8 COL6A3 SFRP4 LAMA2 SSPN PDE8B TLN2 PALLD	2.53e-07	200	141	8	251fd2923f108cd2086961d897244b392c32ad54
ToppCell	LPS_only-Mesenchymal_myocytic\|LPS_only / Treatment groups by lineage, cell group, cell type	SEMA3C SFRP4 LAMA2 ARHGEF17 GFRA2 SSPN FRZB PALLD	2.53e-07	200	141	8	8bc9923f82bfb836e2f524204c92050edeae8ca5
ToppCell	LPS_IL1RA-Mesenchymal_myocytic\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	SEMA3C SFRP4 LAMA2 ARHGEF17 GFRA2 SSPN PDE8B PALLD	2.53e-07	200	141	8	77631c471cc5d453a749784f838cfa6408caf09b
ToppCell	normal_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	EPS8 OBSCN IGF2R ADAMTS9 PDE8B MCTP2 EPAS1	1.20e-06	170	141	7	d69c0ea4cb6b204f19d0a5d2164afb42184779ac
ToppCell	PBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c07-AHNAK\|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)	POLR2C TGM5 IGFBP3 IRF2BPL KCNAB3 ZRANB1 SMAD7	1.25e-06	171	141	7	7b0783d25055e5ea5b2fc44ebcb16bfd0adbcf81
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-Pericytes-Contractile_pericyte_(PLN+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	LAMA5 ARHGEF17 ADAMTS10 FRZB KCNT1 PALLD EPAS1	1.51e-06	176	141	7	90f36f10c6ed440a0ca549f23219398853f1fbc3
ToppCell	COVID-19-Heart-CM_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 SGCG OBSCN LAMA2 TMEM71 KLHL31 PALLD	1.51e-06	176	141	7	9df7a124ebafb0087da0cda133a394275d7bed81
ToppCell	356C-Fibroblasts-Fibroblast-G\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 COL6A6 SGCG PTPRD FRZB PCDH15 SEC14L5	1.57e-06	177	141	7	8220cc2fc0ee8764a67a3be51d75248be2453040
ToppCell	356C-Fibroblasts-Fibroblast-G-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 COL6A6 SGCG PTPRD FRZB PCDH15 SEC14L5	1.57e-06	177	141	7	7617270f49cd6b7ba66db72d20560cee985012b2
ToppCell	3'-GW_trimst-2-LargeIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 XIRP1 ARHGEF17 ADAMTS9 FRZB TLN2 EPAS1	1.63e-06	178	141	7	e5e4742e35c3d90f82b830d77bdbdc45828c7deb
ToppCell	COVID-19-Heart-CM_+_EC_+_Pericyte\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 SGCG OBSCN LAMA2 TMEM71 KLHL31 PALLD	1.82e-06	181	141	7	719eb532453ab7cd7893726885bc75d74a10b21e
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	COL6A3 COL6A6 SGCG LAMA2 PTPRD PCDH15 PALLD	1.82e-06	181	141	7	9ede19228ba5c0668a9c06c915510b95585216ef
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	EPS8 CPAMD8 ARFGEF3 PTPN13 PTPRD PTPRK GPC5	1.82e-06	181	141	7	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	Basal\|World / shred by cell class for mouse tongue	SEMA3C LAMA5 CARD10 CPN1 PTK7 IGFBP3 IRF2BPL	1.96e-06	183	141	7	c6729a207526ff4aa48176207b9353176f631fea
ToppCell	COVID-19-Endothelial_cells-Arterial_endothelial_cells\|COVID-19 / group, cell type (main and fine annotations)	ANO2 CPAMD8 SLCO4A1 HMCN2 IGFBP3 ADAMTS9 EPAS1	2.03e-06	184	141	7	0f19494789f38ab1a420545e15e748ca7eb345c3
ToppCell	COVID-19-Heart-CM_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	XIRP1 SGCG OBSCN LAMA2 TMEM71 KLHL31 PALLD	2.11e-06	185	141	7	549eeb521c3985bff396ea0f202db21822efa51f
ToppCell	COVID-19-Epithelial_cells-Airway_club\|COVID-19 / group, cell type (main and fine annotations)	EPS8 ARFGEF3 DUOX1 PTPN13 PTPRD PTPRK GPC5	2.11e-06	185	141	7	cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCell	LPS-IL1RA+antiTNF-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	COL6A3 SEMA3C SFRP4 LAMA2 SSPN MCTP2 PALLD	2.11e-06	185	141	7	3b2dfc8f4c87be516265dbecfc251276034d0efd
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	ANO2 SLCO4A1 CEMIP2 ADAMTS9 PCDH15 EPAS1 HYAL2	2.26e-06	187	141	7	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	Fetal_29-31_weeks-Mesenchymal-pericyte_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	EPS8 COL6A3 OBSCN ARHGEF17 ADAMTS9 PDE8B STARD9	2.26e-06	187	141	7	a2bf958ea59c359a265bfa437d59315e1920cdd4
ToppCell	5'-Adult-LargeIntestine-Mesenchymal-fibroblastic-Stromal_2_(NPY+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL6A3 OBSCN LAMA5 PTPN13 IGFBP3 FRZB MCTP2	2.34e-06	188	141	7	997dcfc4f08738ab398d8abc15e4fd2fc6619862
ToppCell	Control-Epithelial_cells\|Control / group, cell type (main and fine annotations)	COL4A3 EPS8 ARFGEF3 DUOX1 PTPN13 PTPRK GPC5	2.34e-06	188	141	7	707ebf76cc6fb600b2f07793cf4ea9482c0de79d
ToppCell	tumor_Lung-Fibroblasts-Pericytes\|Fibroblasts / Location, Cell class and cell subclass	EPS8 LAMA5 ARHGEF17 IGF2R ADAMTS9 PDE8B KCNT1	2.43e-06	189	141	7	9c407b17d7945e81e1ae6c18452f5d20fb09d563
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Mesenchymal-Myocytic_interstitial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	EPS8 ARHGEF17 STARD9 FRZB KCNT1 PALLD EPAS1	2.43e-06	189	141	7	fac5c291a9a87418bb0878c3d624829bdbf1f428
ToppCell	Mesenchymal-pericyte_cell\|World / Lineage, Cell type, age group and donor	COL6A3 OBSCN LAMA2 ARHGEF17 ADAMTS9 PDE8B STARD9	2.43e-06	189	141	7	d7ed96add29f219183c802895fbff519b627f635
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EPS8 COL6A3 OBSCN ARHGEF17 ADAMTS9 PDE8B STARD9	2.51e-06	190	141	7	4eb92aef1ee868f4537483d19014d947b7684612
ToppCell	COVID-19-Heart-EC_+_Pericyte\|Heart / Disease (COVID-19 only), tissue and cell type	EPS8 ANO2 CPAMD8 LAMA5 ARHGEF17 ADAMTS9 EPAS1	2.51e-06	190	141	7	a21653bfb7bafbc273f94fa7c13bfb48cf8fd562
ToppCell	nucseq-Mesenchymal-Myocytic-Myocytic_1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	EPS8 COL6A3 OBSCN ARHGEF17 ADAMTS9 PDE8B STARD9	2.51e-06	190	141	7	7be4341e2909101d756f14031c21e705eb45e69a
ToppCell	E16.5-samps-Mesenchymal-Matrix_fibroblast-_fetal\|E16.5-samps / Age Group, Lineage, Cell class and subclass	COL6A3 GFRA2 PTK7 IGF2R PTPRD MCTP2 PALLD	2.60e-06	191	141	7	3379d145d34f89150f7b06d1340022cfc6b4a6ce
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l49\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LAMA2 ARHGEF17 GFRA2 PTK7 PTPRD IGFBP3	2.60e-06	191	141	7	c715bbdbbf1482aad45a50a16d5232fd35a9a0bb
ToppCell	droplet-Lung-21m-Mesenchymal-fibroblast-alveolar_fibroblast\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LAMA2 ARHGEF17 GFRA2 PTK7 PTPRD IGFBP3	2.60e-06	191	141	7	243d83cbfcc4996ad087ec6386e559e0b8662004
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	COL4A3 CPAMD8 DSCAM LAMA5 PTPN13 PTPRK GPC5	2.60e-06	191	141	7	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	RV-01._Fibroblast_I\|World / Chamber and Cluster_Paper	COL4A3 EPS8 COL6A3 DYNC2H1 LAMA2 PTPRD STARD9	2.60e-06	191	141	7	70c067c54084bfb02c29bab085f4defd477194fb
ToppCell	droplet-Lung-30m-Mesenchymal\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL6A3 LAMA2 ARHGEF17 GFRA2 PTK7 PTPRD IGFBP3	2.69e-06	192	141	7	5d5bec238b196f0b3e727fd94f078d6ae524cb01
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LAMA2 GFRA2 PTK7 PTPRD IGFBP3 PALLD	2.79e-06	193	141	7	4c74a3f69b2cbdf139e7e66b44bd86869ac34dc0
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL6A3 LAMA2 GFRA2 PTK7 PTPRD IGFBP3 PALLD	2.79e-06	193	141	7	ff8ceeb3cfd1bef7239df490c19d181091750833
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LAMA2 ARHGEF17 IGFBP3 ADAMTS9 FRZB TLN2	2.89e-06	194	141	7	415801a3dfacf05f2b603fb424df3d045190a812
ToppCell	PND01-03-samps-Mesenchymal\|PND01-03-samps / Age Group, Lineage, Cell class and subclass	CDKN1C COL6A3 GFRA2 PTK7 IGF2R PTPRD PALLD	2.89e-06	194	141	7	4f9bd0ded0dde1df885850714f29e73e992539a5
ToppCell	3'-GW_trimst-1-SmallIntestine-Mesenchymal-Pericytes-Immature_pericyte\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	EPS8 COL6A3 ARHGEF17 ADAMTS9 FRZB TLN2 EPAS1	2.89e-06	194	141	7	7a7406c3b021aeafde423d20290c681c3e8ea0a6
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal-hepatic_stellate_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LAMA2 ARHGEF17 IGFBP3 ADAMTS9 FRZB TLN2	2.89e-06	194	141	7	256cb33ec90328f2704921fb0fe0fd9812e138b0
ToppCell	Children_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	EPS8 ARFGEF3 DUOX1 PTPN13 PTPRD PTPRK ADAMTS9	2.89e-06	194	141	7	97534c8bba895a7913665e03ae4e5c4a6ad71daf
ToppCell	droplet-Liver-LIVER-NPC-1m-Mesenchymal\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL6A3 LAMA2 ARHGEF17 IGFBP3 ADAMTS9 FRZB TLN2	2.89e-06	194	141	7	7942bc83c1bdca687795b91aa232824d603f9b09
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	CDKN1C ANO2 CPAMD8 SLCO4A1 CARD10 EPAS1 HYAL2	2.99e-06	195	141	7	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	COL4A3 EPS8 ARFGEF3 DUOX1 PTPN13 PTPRK GPC5	2.99e-06	195	141	7	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPS8 LAMA2 GRM3 ARHGEF17 PDE8B FRZB EPAS1	3.09e-06	196	141	7	cb61757646653f89faba503cb5d99e5dd5197b4c
ToppCell	severe_COVID-19-Non-classical_Monocyte\|severe_COVID-19 / disease group, cell group and cell class (v2)	CDKN1C PIK3AP1 EPS8 GFRA2 LFNG SLC7A8 SEZ6L	3.09e-06	196	141	7	34c1c74cad5e23196e86cfd6f19c836fe57b2264
ToppCell	Parenchymal-10x5prime-Stromal-Fibroblastic-Fibro_immune_recruiting\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	HMCN2 PTPRD PLA2G4C IGFBP3 FRZB TMEM59L TLN2	3.09e-06	196	141	7	614a07334707eafe238d5cb7b080a3ca796a1920
ToppCell	3'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	COL6A3 COL6A6 SGCG LAMA2 PTPRD PCDH15 PALLD	3.09e-06	196	141	7	cecf82cd5e0a3835d655f5e7478578674a63ce25
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Vascular-Mural_cell-Scavenging_pericyte-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	EPS8 LAMA2 GRM3 ARHGEF17 PDE8B FRZB EPAS1	3.09e-06	196	141	7	44e2df1b61e3819eae7e482bef0a733afe852d67
ToppCell	IPF-Stromal-Myofibroblast\|Stromal / Disease state, Lineage and Cell class	COL6A3 COL6A6 LAMA2 PTK7 PTPRD MCTP2 PALLD	3.19e-06	197	141	7	f304d42fc4936fe20996e07c8dccc698a6e5e5ef
ToppCell	Tracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SPEG LAMA5 ARHGEF17 ADAMTS10 PLA2G4C ADAMTS9 KCNT1	3.30e-06	198	141	7	7dd874b09c81cc512ccc1e9b65f290a5f94d736e
ToppCell	COVID-19-lung-Capillary_2\|lung / Disease (COVID-19 only), tissue and cell type	ANO2 LAMA5 SLCO4A1 CEMIP2 ADAMTS9 EPAS1 HYAL2	3.41e-06	199	141	7	793ce71b78a68033ef4419ed571e1dd86b40124f
ToppCell	Endothelial_cells-Endothelial-A\|Endothelial_cells / lung cells shred on cell class, cell subclass, sample id	EPS8 LAMA5 SLCO4A1 CEMIP2 DHX8 IGFBP3 EPAS1	3.41e-06	199	141	7	2a1424c61ddcd1fea9574f7a3ad1955387458130
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 SSPN PTPN13 IGFBP3 ADAMTS9 FRZB PALLD	3.41e-06	199	141	7	9b2262edbdec89166d895ab97527e0ee5f9b6010
ToppCell	Parenchymal-NucSeq-Epithelial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	COL4A3 EPS8 ARFGEF3 DUOX1 PTPN13 PTPRK GPC5	3.41e-06	199	141	7	5cea0d9e261903e0eaad60c28a07dff72ce65027
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 SSPN PTPN13 IGFBP3 ADAMTS9 FRZB PALLD	3.41e-06	199	141	7	251b3643dcd8f4645b17101bd716e66f12a20e88
ToppCell	LPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	COL6A3 SEMA3C LAMA2 PTK7 SSPN MCTP2 PALLD	3.41e-06	199	141	7	38cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCell	10x3'2.3-week_17-19-Mesenchymal_fibro-stroma-arteriolar_fibroblast\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	EPS8 COL6A3 COL6A6 LAMA2 LAMB2 SSPN TMEM59L	3.41e-06	199	141	7	95d95e9b7bd3933188998ae94986213eb0f1e5ea
ToppCell	Tracheal-10x3prime_v2-Endothelial-Endothelia_vascular-VE_pulmonary_arterial\|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations	ANO2 CPAMD8 SLCO4A1 IGFBP3 EPAS1 HYAL2 SMAD7	3.41e-06	199	141	7	fff88d2bba262583bb726900ae01e44954b72eb9
ToppCell	LPS_IL1RA_TNF-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	CDKN1C COL6A3 COL6A6 DYNC2H1 PTK7 PTPRD PALLD	3.41e-06	199	141	7	30d3e8c0681ec11f86dd38c5f48d21187a1b4f90
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	COL6A3 SEMA3C SFRP4 PTK7 SSPN MCTP2 PALLD	3.41e-06	199	141	7	6b3a0e5d52a30d0eed30e6a670f5b53bc233f70c
ToppCell	10x5'v1-week_14-16-Mesenchymal_adipo-stroma-adipo-CAR\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 SSPN PTPN13 IGFBP3 ADAMTS9 FRZB PALLD	3.41e-06	199	141	7	117f4f43b6c06dda553799b1063e827bce697370
ToppCell	Biopsy_Other_PF-Mesenchymal-Myofibroblasts\|Biopsy_Other_PF / Sample group, Lineage and Cell type	COL6A3 SFRP4 COL6A6 LAMA2 SSPN PTPRD PALLD	3.53e-06	200	141	7	e504570fd7eec1524c401b1cfa9d10822d80d994
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CDKN1C COL6A3 SFRP4 LAMA2 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	e663995fc44c340d878d66b278b7b5c2ff784301
ToppCell	distal-2-mesenchymal-Alveolar_Fibroblast\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	COL6A3 SFRP4 COL6A6 SGCG LAMA2 FRZB PALLD	3.53e-06	200	141	7	12b705dabec1b3752a488a891eda1a5123fcdc41
ToppCell	Control_saline-Mesenchymal_fibroblastic\|Control_saline / Treatment groups by lineage, cell group, cell type	CDKN1C COL6A3 COL6A6 GFRA2 PTK7 PTPRD PCDH15	3.53e-06	200	141	7	64ae5cf6cb4fc94cf1052abd82648f6b8e6445fe
ToppCell	LPS_IL1RA_TNF-Mesenchymal_myocytic\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	SEMA3C SFRP4 LAMA2 ARHGEF17 GFRA2 MCTP2 PALLD	3.53e-06	200	141	7	f599e4b051ac3dad11ad437e98dc8ea6754cca53
ToppCell	LPS_IL1RA-Mesenchymal_myocytic-Pericyte-Pericyte_2\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	EPS8 COL6A3 COL6A6 LAMA2 ARHGEF17 GFRA2 PDE8B	3.53e-06	200	141	7	cf883ba5dbe6350b93142d625a52b25ff2a8bb63
ToppCell	Parenchyma_Control_(B.)-Stromal-TX-Fibroblasts-1\|Parenchyma_Control_(B.) / Sample group, Lineage and Cell type	COL6A3 COL6A6 LAMA2 PTPRD FRZB PCDH15 PALLD	3.53e-06	200	141	7	aa1a35dcca3b799241eef4237f6eb94660e019f0
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)-\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 SFRP4 LAMA2 PTK7 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	082e718c1da3f4fdd33a001d15ad3ddb2be985c7
ToppCell	Control_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A3 SEMA3C SFRP4 PTK7 SSPN MCTP2 PALLD	3.53e-06	200	141	7	a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCell	Control_saline-Mesenchymal_myocytic\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A3 SEMA3C SFRP4 LAMA2 ARHGEF17 SSPN PALLD	3.53e-06	200	141	7	5ed4261157cd51109b314818133ac3a0d34ee5fa
ToppCell	Lung_Parenchyma-Control-Mesenchymal-Mesenchymal-Fibroblasts-1\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	COL6A3 COL6A6 LAMA2 PTPRD FRZB PCDH15 PALLD	3.53e-06	200	141	7	a510deaada669e690329183e18df02870bd204b3
ToppCell	367C-Fibroblasts-Fibroblast-B_(Myofibroblast)\|367C / Donor, Lineage, Cell class and subclass (all cells)	COL6A3 SFRP4 LAMA2 PTK7 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	731e55070a7ff315091855bd88cda30e5a7e1a98
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro-stroma\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 SEMA3C COL6A6 LAMA2 SSPN TMEM59L GPC5	3.53e-06	200	141	7	64d2941689d7ca8af54f9ba21c5aeabf719084ef
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-\|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	CDKN1C COL6A3 SFRP4 LAMA2 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	2cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCell	Lung_Parenchyma-Severe-Mesenchymal\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CDKN1C COL6A3 SFRP4 LAMA2 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	6ce8e2cf689523993d909a27daec3d6a5824d13c
ToppCell	Lung_Parenchyma-Severe-Mesenchymal-Mesenchymal\|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)	CDKN1C COL6A3 SFRP4 LAMA2 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	907427e85cebe5a18c8a310e2ffa0e180ea3cb77
ToppCell	LPS_only-Mesenchymal_myocytic-Pericyte\|LPS_only / Treatment groups by lineage, cell group, cell type	LAMA2 ARHGEF17 GFRA2 PDE8B FRZB TMEM59L PALLD	3.53e-06	200	141	7	8c8ef2b19ab5b1bfc0fae6c38a330f464f28e86f
ToppCell	LPS_only-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast\|LPS_only / Treatment groups by lineage, cell group, cell type	COL6A3 SFRP4 LAMA2 PTK7 SSPN MCTP2 PALLD	3.53e-06	200	141	7	a9ff3210127000b3dd9e97136163c98c2b0817d7
ToppCell	Parenchyma_COVID-19-Stromal-TX-Fibroblasts-3\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CDKN1C COL6A3 SFRP4 LAMA2 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	8cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell	LPS_only-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|LPS_only / Treatment groups by lineage, cell group, cell type	CDKN1C COL6A3 COL6A6 DYNC2H1 CEMIP2 PTK7 PTPRD	3.53e-06	200	141	7	a7ef7022b8efcaedb7319b0b43d8c4e99d788fe2
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts\|Control_saline / Treatment groups by lineage, cell group, cell type	CDKN1C COL6A3 COL6A6 GFRA2 PTK7 PTPRD PCDH15	3.53e-06	200	141	7	a1fc74c1b27e104895910bc7cdce7ba33d30df7e
ToppCell	Parenchyma_COVID-19-Stromal-TX\|Parenchyma_COVID-19 / Sample group, Lineage and Cell type	CDKN1C COL6A3 SFRP4 LAMA2 SSPN IGFBP3 PALLD	3.53e-06	200	141	7	8472baa74c48b67c5f08223025885c833458290b
ToppCell	Control_saline-Mesenchymal_fibroblastic-Fibroblasts-MatrixFB\|Control_saline / Treatment groups by lineage, cell group, cell type	COL6A3 CPAMD8 COL6A6 GFRA2 PTK7 PTPRD PCDH15	3.53e-06	200	141	7	bd8cf33502adea320e91ca2af14e1911d88ad374
ToppCell	10x3'2.3-week_12-13-Mesenchymal_fibro\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	COL6A3 SEMA3C COL6A6 LAMA2 SSPN TMEM59L GPC5	3.53e-06	200	141	7	76f3043cb88071256ff661885fe5a82a54f5b733
Computational	Genes in the cancer module 387.	COL6A3 SGCG SPEG LAMA2 SSPN	4.71e-05	49	88	5	MODULE_387
Computational	Genes in the cancer module 329.	COL6A3 SGCG SPEG LAMA2 SSPN	5.73e-05	51	88	5	MODULE_329
Drug	Mebendazole [31431-39-7]; Up 200; 13.6uM; MCF7; HT_HG-U133A	ANO2 DSCAM SSPN PTPRD PLA2G4C IGFBP3 PDE8B EPAS1	1.61e-05	180	140	8	4694_UP
Drug	colcemid; Up 200; 11.7uM; MCF7; HT_HG-U133A_EA	EPPK1 TROAP HECTD4 PI4K2A LAMB2 PLCG1 PALLD HYAL2	2.37e-05	190	140	8	1103_UP
Drug	Dyclonine hydrochloride [536-43-6]; Down 200; 12.2uM; MCF7; HT_HG-U133A	ZSWIM8 FXR2 DYNC2H1 POLG POLR2C LAMB2 TSC22D2 TLN2	2.96e-05	196	140	8	7022_DN
Drug	Ebselen [60940-34-3]; Up 200; 14.6uM; HL60; HT_HG-U133A	SFRP4 CARD10 ARHGEF17 CEMIP2 SLC7A8 ALOXE3 MCTP2 PALLD	2.96e-05	196	140	8	2717_UP
Drug	Trihexyphenidyl-D,L Hydrochloride [58947-95-8]; Up 200; 11.8uM; HL60; HT_HG-U133A	PI4K2A DEF8 ABCG4 ARNT KAT8 KDM8 CAMSAP2 PALLD	3.18e-05	198	140	8	2158_UP
Drug	Methazolamide [554-57-4]; Up 200; 17uM; PC3; HT_HG-U133A	ANO2 ZSWIM8 TASL ARNT ADAMTS9 KAT8 TLN2 ALOXE3	3.30e-05	199	140	8	5794_UP
Drug	Mephenytoin [50-12-4]; Up 200; 18.4uM; MCF7; HT_HG-U133A	CDKN1C POLG MINDY2 TASL SLC7A8 SSPN ARNT KAT8	3.30e-05	199	140	8	3580_UP
Drug	troglitazone; Up 200; 10uM; HL60; HT_HG-U133A	SEMA3C DSCAM MINDY2 SSPN PTPRD KAT8 TLN2 SIGLEC1	3.30e-05	199	140	8	6191_UP
Drug	Myosmine [532-12-7]; Up 200; 27.4uM; HL60; HT_HG-U133A	DSCAM SLC7A8 PTPN13 PLA2G4C IGFBP3 PDE8B ALOXE3 SEZ6L	3.30e-05	199	140	8	2199_UP
Drug	oxamic acid sodium salt; Down 200; 10000uM; MCF7; HG-U133A	GAK FXR2 SLC7A8 ARNT TMEM59L TLN2 HSPA4 SEZ6L	3.30e-05	199	140	8	439_DN
Drug	Guanadrel sulfate [22195-34-2]; Up 200; 7.6uM; HL60; HT_HG-U133A	CDKN1C PCYT1A ZSWIM8 ERCC4 SPEG LAMA2 MINDY2 KDM8	3.42e-05	200	140	8	2575_UP
Drug	FK-506; Down 200; 1uM; MCF7; HG-U133A	ZSWIM8 ERCC4 SFRP4 NAPG GRPR TLN2 SIGLEC1 HSPA4	3.42e-05	200	140	8	378_DN
Drug	AC1L1G72	LAMA2 LAMA5 LAMB2	3.62e-05	11	140	3	CID000003553
Disease	scoliosis (implicated_via_orthology)	PTK7 ADAMTS9	2.15e-04	5	138	2	DOID:0060249 (implicated_via_orthology)
Disease	Colorectal Neoplasms	CPAMD8 SFRP4 ARNT PTPRD IGFBP3 SMAD7 PMM2	3.39e-04	277	138	7	C0009404
Disease	Colorectal Carcinoma	CPAMD8 SFRP4 OBSCN DNALI1 ARNT PTPRD IGFBP3 INTS13 CAMSAP2 SMAD7 PMM2	4.79e-04	702	138	11	C0009402
Disease	calpastatin measurement	CPN1 SIGLEC1	5.97e-04	8	138	2	EFO_0008065
Disease	short-term memory	PTPRD PTPRK FRZB PCDH15	6.32e-04	83	138	4	EFO_0004335
Disease	egg allergy measurement	ERCC4 ITIH6	7.65e-04	9	138	2	EFO_0007018
Disease	Parkinson disease, disease progression measurement	ANO2 PTPRD MCTP2	8.09e-04	39	138	3	EFO_0008336, MONDO_0005180
Disease	Russell-Silver syndrome	CDKN1C IGFBP3	9.53e-04	10	138	2	C0175693
Disease	insulin sensitivity measurement, response to polyunsaturated fatty acid supplementation	EPS8 TLN2	1.16e-03	11	138	2	EFO_0004471, EFO_0009131
Disease	Alzheimer disease, APOE carrier status	COL6A3 DSCAM GPC5 MCTP2	1.18e-03	98	138	4	EFO_0007659, MONDO_0004975
Disease	coronary artery disease	COL6A3 SEMA3C DSCAM DYNC2H1 HECTD4 LAMB2 PTK7 IGF2R KCNJ13 PLCG1 MCTP2 PALLD SEZ6L SMAD7	1.45e-03	1194	138	14	EFO_0001645
Disease	Bipolar Disorder	DSCAM POLG NAPG GRM3 STARD9 PLCG1 HSPA4 SEZ6L	1.87e-03	477	138	8	C0005586
Disease	trimethylamine-N-oxide measurement	INTS13 UBE3C	1.90e-03	14	138	2	EFO_0010541
Disease	cerebellum cortex volume change measurement	PTPRD EPAS1	1.90e-03	14	138	2	EFO_0021497
Disease	response to lithium ion	SLCO4A1 GFRA2 EPAS1	2.31e-03	56	138	3	GO_0010226
Disease	coronary thrombosis, GM11992	DSCAM PALLD	2.50e-03	16	138	2	EFO_0001124, EFO_1000883
Disease	creatinine measurement	DSCAM SPEG OBSCN LAMA2 LAMA5 CARD10 LFNG DUOX1 IGF2R DOCK7 EPAS1 SMAD7	2.53e-03	995	138	12	EFO_0004518
Disease	muscular dystrophy (is_implicated_in)	COL6A3 LAMA2	2.82e-03	17	138	2	DOID:9884 (is_implicated_in)
Disease	tuberculosis	DSCAM DYNC2H1 POLG TGM5 PTPRD	3.54e-03	216	138	5	MONDO_0018076
Disease	electrocardiography	SPEG OBSCN GMEB2 HMCN2 RNF10 PALLD EPAS1 SMAD7	3.57e-03	530	138	8	EFO_0004327
Disease	rheumatoid arthritis (is_marker_for)	SEMA3C HSPA4 EPAS1	4.19e-03	69	138	3	DOID:7148 (is_marker_for)
Disease	muscular dystrophy (implicated_via_orthology)	SGCG LAMA2	4.30e-03	21	138	2	DOID:9884 (implicated_via_orthology)
Disease	nephrotic syndrome	TSC22D2 PTPRD GPC5	4.54e-03	71	138	3	EFO_0004255

Protein segments in the cluster

Peptide	Gene	Start	Entry
SPYDRAVLISACERG	TMEM59L	66	Q9UK28
FVVPDSISRYCREGS	nan	101	Q6ZS92
TISRGCLTEQTYPEV	PPP2R5E	101	Q16537
CETGRVVYVSDSVTP	ARNT	181	P27540
RYDCEVNVPVLGSST	EPAS1	841	Q99814
IEFVELSYSVREGPC	ABCG4	61	Q9H172
DEEEVLSTYRFPCRV	CARD10	61	Q9BWT7
PVCVYTRDEVTGEAA	ASPSCR1	136	Q9BZE9
ITGRALEPYISRCTV	COL4A3	1536	Q01955
ELCPSEASPYVRSRE	EIF2AK3	786	Q9NZJ5
RSRAEYTEASGPCIL	ADO	171	Q96SZ5
CPYHIRTGEEARVSL	APOBEC4	31	Q8WW27
YVPTVCNGREVLDST	GRM3	861	Q14832
IGTVPTVDLASRYEC	ABHD17A	191	Q96GS6
ALETYGVDPSRVVVC	AADACL4	176	Q5VUY2
RAPNTEDTGLCRVLY	AP5S1	11	Q9NUS5
LYGCATIEEDIPSRE	ANO2	386	Q9NQ90
VQPDRIRCGAETTVY	PIK3AP1	181	Q6ZUJ8
YTERAAAVVDGTPCR	ADAMTS10	651	Q9H324
LEAEIVYPITCGDSR	GMEB2	86	Q9UKD1
TGCTQIRYSVPEELE	PCDHGA12	26	O60330
CTGAYRISPVDVNSR	INTS13	331	Q9NVM9
EYLGCRRVPRDTLDT	P2RY8	306	Q86VZ1
CVVVYPEVERGSGTE	SLC7A8	491	Q9UHI5
YRPSEDIVGVRCEEE	RDM1	231	Q8NG50
LELCATRPEGTDSYI	ARHGEF17	1436	Q96PE2
LREIYSAPTGDRCAR	DUOX1	1346	Q9NRD9
TCEARYEAVSPERLE	MAML1	36	Q92585
VASGRYCQPEEEVAR	DNAJC14	416	Q6Y2X3
ESYTGRCPDVEVARN	HYAL2	221	Q12891
RGERVDVLTVECYSP	KLHL31	526	Q9H511
TAERIRLPDDCTIGY	LFNG	281	Q8NES3
LVVRDRCGTSDPYVK	MCTP2	206	Q6DN12
VVSVPCFYTDAERRS	HSPA4	141	P34932
GETPEACRQARSYLE	FXR2	276	P51116
PGVTDSSLEYSECIR	GPC5	181	P78333
IPAAQERDAGTYTCR	HMCN2	751	Q8NDA2
PEVTVEIGETYLCRR	KAT8	51	Q9H7Z6
EGYCTVELRPGTART	ALOXE3	106	Q9BYJ1
CSSSAEIPIGIYRTE	KCNT1	1011	Q5JUK3
GCRTVPVEVGSRYTD	KDM8	231	Q8N371
VTIARHYRVPEGTCS	EFHC2	601	Q5JST6
RDTLLTLAGCTPYEV	IRF2BPL	376	Q9H1B7
EASRGTPCERPVRVY	PCYT1A	66	P49585
RLSRAGPSYAVCEVE	FAT2	4301	Q9NYQ8
ICDPLRYATVLTTEV	OR51I2	126	Q9H344
GYRCNIARTPESALE	PDE8B	156	O95263
ESAGVVCPYRAIESL	POLG	641	P54098
EGTGEICQRRTSYLP	KCNJ13	276	O60928
VCESRYSEIEPSTEG	LAMB2	201	P55268
TRRIGPVTYSIDGCV	LAMA2	2896	P24043
LRDEGYTFCESPRSV	MUC5AC	1981	P98088
DAAICTTEYSRIVPL	LAMA5	211	O15230
IPYTRSEEKCLVRSG	HECTD4	1276	Q9Y4D8
GEARPVETLRACEEY	MROH1	36	Q8NDA8
TTPVCEDIGRSLLTY	UQCRC1	406	P31930
GDTYDRVLVDVPCTT	NSUN4	246	Q96CB9
VYICETPEGSRTVAE	OBSCN	401	Q5VST9
IERCIFPERIYQGSS	PI4K2A	121	Q9BTU6
EPVTSRDAGIYTCIA	PALLD	1196	Q8WX93
PAERRNSICTVYIEV	PCDH15	591	Q96QU1
DPFETIRATTDYCRR	PLA2G4C	416	Q9UP65
RPFCEVYVGDERVAS	GAK	596	O14976
FTSIVRLCSIDYPER	DYNC2H1	2421	Q8NCM8
CISLPVYTSAERDRV	DYNC2H1	4266	Q8NCM8
IARETECNPYTRPES	ADAMTS9	1531	Q9P2N4
ECPGITRVYSIGRSV	CPN1	41	P15169
DIEVVYSPRDCRTLV	DOCK7	86	Q96N67
RGRPICIATDDYESE	DOCK7	1266	Q96N67
ERRRQTILPSCSYED	GFRA2	231	O00451
SVPAFYRETVQVGRC	CDKN1C	86	P49918
PTETISRVGCSCIRY	ARFGEF3	1576	Q5TH69
PRYIQDLDACETGTV	CPAMD8	236	Q8IZJ3
ITCAPVDASRYLADR	GRPR	91	P30550
ESNCPRGARVAVVTY	COL6A3	2436	P12111
EPTRKYGITEDCTSL	IDI2-AS1	141	Q9NZ38
QLDEYGCPRATTVRR	CEMIP2	1356	Q9UHN6
ESVLCVQYTEEPRIR	DNAJC9	146	Q8WXX5
RETGICPVRRELYSQ	DNALI1	116	O14645
ERDPRSLTLYVEVAC	MAN2C1	136	Q9NTJ4
IERGETCVRITYCPT	ITIH6	216	Q6UXX5
SLRGVPSEARQCDYT	DEF8	286	Q6ZN54
DELRTVCPEGARVYS	EPS8	761	Q12929
ATGILDPCIYRVSVR	FAM102B	71	Q5T8I3
ATCSADGIVRIYEAP	SEH1L	131	Q96EE3
GRDYSRVEAPLVCRE	SEC14L5	581	O43304
LRATSCGLEEPVSYR	SPACA4	66	Q8TDM5
YDIRTGNTREALSPC	CAMSAP2	661	Q08AD1
TCELIQYVRDRSPGR	COL6A6	1731	A6NMZ7
EVGYTIRFEDCTSPE	DHX8	641	Q14562
CTGPESRREVPVYTD	FAM120B	356	Q96EK7
GETATYRRCHPEAVT	PTPN13	316	Q12923
SRLLDVPRYLCEGTE	PTPRK	841	Q15262
DTTRYERGVCVSAVI	OR2AJ1	191	Q8NGZ0
YESTRVCLQPIRGVE	PTPRD	1681	P23468
DCTRVASPAYSLVRR	ODF3L2	61	Q3SX64
SSESKRETEYGPCRR	IGFBP3	201	P17936
LITSKYDGRVPDTCR	KCNAB3	291	O43448
PIGRSCSQEERIEFY	PMM2	131	O15305
ENIRPSDSGSYVCEV	DSCAM	281	O60469
AVTITFVCPSERREG	IGF2R	281	P11717
VRFTGVRVFEYTPEC	MINDY2	341	Q8NBR6
TELVRGARITYQCDP	SEZ6L	761	Q9BYH1
YTIPEDGRVSENTVC	STK40	291	Q8N2I9
SRLEREYAGELSPTC	TMEM71	16	Q6P5X7
SPVCTYLNRGRRSED	SEMA3C	136	Q99985
VSRATDYGPEEVCER	TSC22D2	51	O75157
ASRPYADVRVIDCGV	NKTR	161	P30414
TATILNPRDTYCRGD	NXPE4	101	Q6UWF7
GRTSYAQLLEECPRD	EPPK1	1091	P58107
PLSRTFVYRDVTDCT	SSPN	171	Q14714
TSCVPNREYVRVFDV	SIRT7	196	Q9NRC8
RGTVLSYCETLLEPE	STARD9	2571	Q9P2P6
CVRLRGLPYTATIED	ESRP2	476	Q9H6T0
SVELLREYISTCVPE	ABCC12	1086	Q96J65
YNVESCGSLRPETIV	POLR2C	231	P19387
YTTATEGICIERPEN	SGCG	6	Q13326
RYEVELDAGVRTCPA	SLCO4A1	196	Q96BD0
RVLPCYLERVSSGIS	C11orf40	101	Q8WZ69
TGTVREYRTERCPLK	PGBD2	371	Q6P3X8
TRVGRLYCVQEPSLD	SMAD7	271	O15105
GDSRAPCTYTLERRV	SPEG	2701	Q15772
PCTYTLERRVDGESV	SPEG	2706	Q15772
VAAERCVRESYSIPG	NAPG	211	Q99747
VYDRGVCISPEAIVT	FRZB	141	Q92765
EICRDASRETYLVPS	TASL	101	Q9HAI6
YDRGVCISPEAIVTD	SFRP4	131	Q6FHJ7
CLVREYGSLERSPEK	RNF10	526	Q8N5U6
VYVCASDVPIRRREE	TECPR1	56	Q7Z6L1
SYCRIEPEIPESSRQ	TROAP	591	Q12815
ERLLTEYCIETGAPD	PLCG1	566	P19174
LPNVTVRDATSYRCG	SIGLEC1	1136	Q9BZZ2
DCALRGSPVYVSRVV	TGM5	211	O43548
ECPYLHRTTGDTERK	UNKL	96	Q9H9P5
AEELREGTLCDYRPV	ZSWIM8	906	A7E2V4
FEPSTAVYDACRVIR	TLN2	21	Q9Y4G6
EEGYRREISSSPESC	ERCC4	511	Q92889
RVKPTDEGTYECRVI	VSTM2L	131	Q96N03
TPCYISLSEDVRRVI	TRIM64C	296	A6NLI5
SVTRNETGPYECEIR	PSG5	206	Q15238
RVFTAGSEERVTCLP	PTK7	331	Q13308
RYCSRVEIPSGQVSR	XIRP1	681	Q702N8
RYRQIRPCTSLSDGE	ZRANB1	686	Q9UGI0
PEDGRLSVSYITEEC	UBE3C	381	Q15386
TQIPEYGDTCDREGR	ZSCAN23	221	Q3MJ62
ECTIRAGEVLYFPDR	JMJD8	231	Q96S16
APELSYRVCVGSDVT	MYORG	276	Q6NSJ0