Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionpalmitoyl-CoA ligase activity

ACSL3 ACSL4

3.63e-053702GO:0090433
GeneOntologyMolecularFunctionNotch binding

JAG2 ATRNL1 CCN3

1.14e-0427703GO:0005112
DomainVWFC_1

JAG2 CCN5 SSPOP CCN3

9.19e-0636694PS01208
DomainVWC

JAG2 CCN5 SSPOP CCN3

1.15e-0538694SM00214
DomainVWFC_2

JAG2 CCN5 SSPOP CCN3

1.15e-0538694PS50184
DomainVWF_dom

JAG2 CCN5 SSPOP CCN3

1.72e-0542694IPR001007
DomainEMI

MEGF6 SSPOP PEAR1

3.16e-0517693PS51041
DomainSushi

PAPPA2 CSMD1 CR1L F13B

4.04e-0552694PF00084
DomainCCP

PAPPA2 CSMD1 CR1L F13B

4.69e-0554694SM00032
DomainSUSHI

PAPPA2 CSMD1 CR1L F13B

5.42e-0556694PS50923
DomainEGF_2

JAG2 MEGF6 ATRNL1 SSPOP F7 PEAR1 EPHA7

5.45e-05265697PS01186
DomainSushi_SCR_CCP_dom

PAPPA2 CSMD1 CR1L F13B

5.81e-0557694IPR000436
DomainCalreticulin/calnexin_P_dom

CLGN ZNF622

1.34e-045692IPR009033
DomainRICIN

GALNT8 GALNT5 LY75

1.48e-0428693SM00458
DomainRICIN_B_LECTIN

GALNT8 GALNT5 LY75

1.48e-0428693PS50231
DomainRicin_B_lectin

GALNT8 GALNT5 LY75

1.82e-0430693IPR000772
DomainKringle-like

CCN5 PRSS12 LY75

2.22e-0432693IPR013806
DomainEGF_3

JAG2 MEGF6 ATRNL1 SSPOP F7 PEAR1

2.30e-04235696PS50026
DomainGrowth_fac_rcpt_

JAG2 CCN5 MEGF6 CCN3 EPHA7

2.79e-04156695IPR009030
DomainEGF_Lam

MEGF6 ATRNL1 PEAR1

2.90e-0435693SM00180
DomainTRYPSIN_SER

PRSS12 CTRB2 CTRB1 F7

3.43e-0490694IPR033116
DomainEGF_1

JAG2 MEGF6 ATRNL1 SSPOP F7 PEAR1

3.57e-04255696PS00022
DomainLaminin_EGF

MEGF6 ATRNL1 PEAR1

3.71e-0438693IPR002049
DomainEGF-like_CS

JAG2 MEGF6 ATRNL1 F7 PEAR1 EPHA7

4.04e-04261696IPR013032
DomainPAZ

PIWIL4 DICER1

4.76e-049692PS50821
DomainPAZ

PIWIL4 DICER1

4.76e-049692SM00949
DomainPAZ_dom

PIWIL4 DICER1

4.76e-049692IPR003100
DomainPAZ

PIWIL4 DICER1

4.76e-049692PF02170
DomainTRYPSIN_HIS

PRSS12 CTRB2 CTRB1 F7

5.73e-04103694IPR018114
DomainTRYPSIN_SER

PRSS12 CTRB2 CTRB1 F7

6.38e-04106694PS00135
DomainTRYPSIN_HIS

PRSS12 CTRB2 CTRB1 F7

6.61e-04107694PS00134
DomainInsulin_GF-bd_Cys-rich_CS

CCN5 CCN3

7.24e-0411692IPR017891
DomainPeptidase_S1A

PRSS12 CTRB2 CTRB1 F7

8.11e-04113694IPR001314
DomainTRYPSIN_DOM

PRSS12 CTRB2 CTRB1 F7

8.66e-04115694PS50240
DomainIGFBP_N_1

CCN5 CCN3

8.67e-0412692PS00222
DomainTryp_SPc

PRSS12 CTRB2 CTRB1 F7

9.24e-04117694SM00020
DomainTrypsin

PRSS12 CTRB2 CTRB1 F7

1.05e-03121694PF00089
DomainTrypsin_dom

PRSS12 CTRB2 CTRB1 F7

1.05e-03121694IPR001254
DomainPeptidase_S1_PA

PRSS12 CTRB2 CTRB1 F7

1.11e-03123694IPR009003
DomainEGF_extracell

JAG2 MEGF6 ATRNL1

1.42e-0360693IPR013111
DomainEGF_2

JAG2 MEGF6 ATRNL1

1.42e-0360693PF07974
DomainEMI_domain

MEGF6 PEAR1

1.56e-0316692IPR011489
DomainTSP_1

CCN5 SSPOP CCN3

1.64e-0363693PF00090
DomainEGF

JAG2 MEGF6 ATRNL1 F7 PEAR1

1.77e-03235695SM00181
DomainTSP1

CCN5 SSPOP CCN3

1.79e-0365693SM00209
DomainTSP1_rpt

CCN5 SSPOP CCN3

1.79e-0365693IPR000884
DomainTSP1

CCN5 SSPOP CCN3

1.79e-0365693PS50092
DomainCTCK_1

SSPOP CCN3

1.98e-0318692PS01185
DomainIB

CCN5 CCN3

1.98e-0318692SM00121
DomainVWC_out

JAG2 SSPOP

2.21e-0319692SM00215
DomainEGF-like_dom

JAG2 MEGF6 ATRNL1 F7 PEAR1

2.27e-03249695IPR000742
DomainIGFBP-like

CCN5 CCN3

2.45e-0320692IPR000867
DomainIGFBP

CCN5 CCN3

2.45e-0320692PF00219
DomainIGFBP_N_2

CCN5 CCN3

2.45e-0320692PS51323
Domain-

HECTD3 SSPOP EPHA7

2.49e-03736932.60.120.260
DomainRicin_B_lectin

GALNT8 GALNT5

3.82e-0325692PF00652
PathwayPID_HEDGEHOG_GLI_PATHWAY

RBBP7 PRKCD PTCH1 SSPOP

3.55e-0548554M219
PathwayWP_FATTY_ACID_BIOSYNTHESIS

ACSL3 ACSL4 ACLY

8.21e-0522553M39440
PathwayWP_FATTY_ACID_BIOSYNTHESIS

ACSL3 ACSL4 ACLY

9.42e-0523553MM15885
PathwayREACTOME_FATTY_ACYL_COA_BIOSYNTHESIS

ACSL3 ACSL4 ACLY

2.57e-0432553MM15446
Pubmed

The CTRB1-CTRB2 risk allele for chronic pancreatitis discovered in European populations does not contribute to disease risk variation in the Chinese population due to near allele fixation.

CTRB2 CTRB1

4.23e-06272228951524
Pubmed

Genome-wide association study identifies inversion in the CTRB1-CTRB2 locus to modify risk for alcoholic and non-alcoholic chronic pancreatitis.

CTRB2 CTRB1

4.23e-06272228754779
Pubmed

No association of KIR3DL1 or KIR3DS1 or their alleles with ankylosing spondylitis.

KIR3DL1 KIR3DS1

4.23e-06272219874556
Pubmed

Evaluation of KIR3DL1/KIR3DS1 polymorphism in Behçet's disease.

KIR3DL1 KIR3DS1

4.23e-06272227708262
Pubmed

Investigation of killer cell immunoglobulin-like receptor gene diversity in KIR3DL1 and KIR3DS1 in a transplant population.

KIR3DL1 KIR3DS1

4.23e-06272218331531
Pubmed

Contribution of KIR3DL1/3DS1 to ankylosing spondylitis in human leukocyte antigen-B27 Caucasian populations.

KIR3DL1 KIR3DS1

4.23e-06272216805919
Pubmed

Role of natural killer cells in a cohort of elite suppressors: low frequency of the protective KIR3DS1 allele and limited inhibition of human immunodeficiency virus type 1 replication in vitro.

KIR3DL1 KIR3DS1

4.23e-06272219211742
Pubmed

Molecular cloning and nucleotide sequence of human pancreatic prechymotrypsinogen cDNA.

CTRB2 CTRB1

4.23e-0627222917002
Pubmed

Allele imputation for the killer cell immunoglobulin-like receptor KIR3DL1/S1.

KIR3DL1 KIR3DS1

4.23e-06272235192601
Pubmed

Genomic cloning and partial characterization of human chymotrypsinogen gene.

CTRB2 CTRB1

4.23e-0627228186414
Pubmed

Immunohistochemical staining reveals differential expression of ACSL3 and ACSL4 in hepatocellular carcinoma and hepatic gastrointestinal metastases.

ACSL3 ACSL4

4.23e-06272232286604
Pubmed

Evaluation of KIR3DL1/KIR3DS1 allelic polymorphisms in Kenyan children with endemic Burkitt lymphoma.

KIR3DL1 KIR3DS1

4.23e-06272237647275
Pubmed

Association of the KIR3DS1*013 and KIR3DL1*004 alleles with susceptibility to ankylosing spondylitis.

KIR3DL1 KIR3DS1

4.23e-06272220131260
Pubmed

NAPE-specific phospholipase D regulates LRRK2 association with neuronal membranes.

NAPEPLD LRRK2

4.23e-06272233706934
Pubmed

Protective genotypes in HIV infection reflect superior function of KIR3DS1+ over KIR3DL1+ CD8+ T cells.

KIR3DL1 KIR3DS1

4.23e-06272225112829
Pubmed

Unusual selection on the KIR3DL1/S1 natural killer cell receptor in Africans.

KIR3DL1 KIR3DS1

4.23e-06272217694054
Pubmed

Contribution of functional KIR3DL1 to ankylosing spondylitis.

KIR3DL1 KIR3DS1

4.23e-06272220818412
Pubmed

MicroRNA Biogenesis and Hedgehog-Patched Signaling Cooperate to Regulate an Important Developmental Transition in Granule Cell Development.

PTCH1 DICER1

4.23e-06272226773048
Pubmed

The endogenous subcellular localisations of the long chain fatty acid-activating enzymes ACSL3 and ACSL4 in sarcoma and breast cancer cells.

ACSL3 ACSL4

4.23e-06272229450800
Pubmed

A method for killer-cell immunoglobulin-like receptor (KIR) 3DL1/3DS1 genotyping using DNA recovered from frozen plasma.

KIR3DL1 KIR3DS1

4.23e-06272223524032
Pubmed

Chymotrypsin Reduces the Severity of Secretagogue-Induced Pancreatitis in Mice.

CTRB2 CTRB1

4.23e-06272230076839
Pubmed

Allele diversity of the killer cell immunoglobulin-like receptors KIR3DL1/S1 and the combination with their HLA ligands in Mexican Mestizos from Mexico City.

KIR3DL1 KIR3DS1

4.23e-06272230365992
Pubmed

Tim4 regulates NALP3 inflammasome expression and activity during monocyte/macrophage dysfunction in septic shock patients.

TIMD4 NLRP3

4.23e-06272231676250
Pubmed

Functional polymorphism of the KIR3DL1/S1 receptor on human NK cells.

KIR3DL1 KIR3DS1

4.23e-06272217182560
Pubmed

Sequencing of the complex CTRB1-CTRB2 locus in chronic pancreatitis.

CTRB2 CTRB1

4.23e-06272233036922
Pubmed

Genetic control of variegated KIR gene expression: polymorphisms of the bi-directional KIR3DL1 promoter are associated with distinct frequencies of gene expression.

KIR3DL1 KIR3DS1

4.23e-06272219008943
Pubmed

Evolutionary relationships between laboratory mice and subspecies of Mus musculus based on the restriction fragment length variants of the chymotrypsin gene at the Prt-2 locus.

CTRB2 CTRB1

4.23e-0627222565717
Pubmed

HLA class I subtype-dependent expansion of KIR3DS1+ and KIR3DL1+ NK cells during acute human immunodeficiency virus type 1 infection.

KIR3DL1 KIR3DS1

4.23e-06272219386717
Pubmed

Putative role of KIR3DL1/3DS1 alleles and HLA-Bw4 ligands with end stage renal disease and long term renal allograft survival.

KIR3DL1 KIR3DS1

4.23e-06272228942035
Pubmed

The profile of KIR3DL1 and KIR3DS1 alleles in an African American population resembles that found in African populations.

KIR3DL1 KIR3DS1

4.23e-06272220230527
Pubmed

Dicer regulates activation of the NLRP3 inflammasome.

DICER1 NLRP3

4.23e-06272231013297
Pubmed

Development of a PCR-SSOP approach capable of defining the natural killer cell inhibitory receptor (KIR) gene sequence repertoires.

KIR3DL1 KIR3DS1

4.23e-06272211098931
Pubmed

Meiotic recombination generates rich diversity in NK cell receptor genes, alleles, and haplotypes.

KIR3DL1 KIR3DS1

4.23e-06272219411600
Pubmed

Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation.

TIMD4 NLRP3

4.23e-06272233567275
Pubmed

Characterization of Acyl-CoA synthetase isoforms in pancreatic beta cells: Gene silencing shows participation of ACSL3 and ACSL4 in insulin secretion.

ACSL3 ACSL4

4.23e-06272228193492
Pubmed

KIR3DS1/L1 and HLA-Bw4-80I are associated with HIV disease progression among HIV typical progressors and long-term nonprogressors.

KIR3DL1 KIR3DS1

1.27e-05372224059286
Pubmed

Genetic study of pancreatic proteinase in mice (Mus musculus): linkage of the Prt-2 locus on chromosome 8.

CTRB2 CTRB1

1.27e-0537221016231
Pubmed

Allelic polymorphism synergizes with variable gene content to individualize human KIR genotype.

KIR3DL1 KIR3DS1

1.27e-05372211859120
Pubmed

Degradomic and yeast 2-hybrid inactive catalytic domain substrate trapping identifies new membrane-type 1 matrix metalloproteinase (MMP14) substrates: CCN3 (Nov) and CCN5 (WISP2).

CCN5 CCN3

1.27e-05372227471094
Pubmed

Allelic expression patterns of KIR3DS1 and 3DL1 using the Z27 and DX9 antibodies.

KIR3DL1 KIR3DS1

1.27e-05372217301953
Pubmed

Evolutionary expansion of polyaspartate motif in the activation peptide of mouse cationic trypsinogen limits autoactivation and protects against pancreatitis.

CTRB2 CTRB1

1.27e-05372234643096
Pubmed

Loss of chymotrypsin-like protease (CTRL) alters intrapancreatic protease activation but not pancreatitis severity in mice.

CTRB2 CTRB1

1.27e-05372232678161
Pubmed

Multiple copies of KIR 3DL/S1 and KIR 2DL4 genes identified in a number of individuals.

KIR3DL1 KIR3DS1

1.27e-05372212826375
Pubmed

Secretagogue-induced pancreatitis in mice devoid of chymotrypsin.

CTRB2 CTRB1

1.27e-05372238981616
Pubmed

KIR3DL1/S1 genotypes and KIR2DS4 allelic variants in the AB KIR genotypes are associated with Plasmodium-positive individuals in malaria infection.

KIR3DL1 KIR3DS1

1.27e-05372219859704
Pubmed

Genetic study of pancreatic proteinase in mice (Mus musculus): genetic variants of trypsin and chymotrypsin.

CTRB2 CTRB1

1.27e-0537221008801
Pubmed

Analysis of killer immunoglobulin-like receptor genes in ankylosing spondylitis.

KIR3DL1 KIR3DS1

1.27e-05372219019897
Pubmed

Characterization of the interactions between mammalian PAZ PIWI domain proteins and Dicer.

PIWIL4 DICER1

2.53e-05472214749716
Pubmed

Expression profile of KIR3DS1/KIR3DL1 receptors in association with immunological responses in TB, HIV and HIV/TB infected patients.

KIR3DL1 KIR3DS1

2.53e-05472237169313
Pubmed

Open conformers of HLA-F are high-affinity ligands of the activating NK-cell receptor KIR3DS1.

KIR3DL1 KIR3DS1

2.53e-05472227455421
Pubmed

Differential expression of CCN1/CYR61, CCN3/NOV, CCN4/WISP1, and CCN5/WISP2 in neurofibromatosis type 1 tumorigenesis.

CCN5 CCN3

2.53e-05472220010302
Pubmed

Activating KIR genes are associated with ankylosing spondylitis in Asian populations.

KIR3DL1 KIR3DS1

2.53e-05472218638658
Pubmed

Polymorphism and domain variability of human killer cell inhibitory receptors.

KIR3DL1 KIR3DS1

2.53e-0547229059894
Pubmed

High-throughput genotyping of KIR2DL2/L3, KIR3DL1/S1, and their HLA class I ligands using real-time PCR.

KIR3DL1 KIR3DS1

2.53e-05472219522772
Pubmed

Fyn kinase regulates misfolded α-synuclein uptake and NLRP3 inflammasome activation in microglia.

PRKCD NLRP3

2.53e-05472231036561
Pubmed

The silent KIR3DP1 gene (CD158c) is transcribed and might encode a secreted receptor in a minority of humans, in whom the KIR3DP1, KIR2DL4 and KIR3DL1/KIR3DS1 genes are duplicated.

KIR3DL1 KIR3DS1

2.53e-05472215580659
Pubmed

Biosynthesis of triacylglycerols.

ACSL3 ACSL4 ACLY

2.69e-05287238944226
Pubmed

DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.

PRKCD NLRP3

4.21e-05572234860583
Pubmed

Chromosomal assignments of genes for trypsin, chymotrypsin B, and elastase in mouse.

CTRB2 CTRB1

4.21e-0557226589791
Pubmed

Genetic study of pancreatic proteinase and alpha-amylase in mice (Mus musculus).

CTRB2 CTRB1

4.21e-0557224461036
Pubmed

Association of killer cell immunoglobulin-like receptor genotypes with microscopic polyangiitis.

KIR3DL1 KIR3DS1

4.21e-05572216508981
Pubmed

Revised nomenclature for the mammalian long-chain acyl-CoA synthetase gene family.

ACSL3 ACSL4

4.21e-05572215292367
Pubmed

Genetic and biochemical characterization of a new chymotrypsin isozyme of the house mouse, CTRA-1.

CTRB2 CTRB1

4.21e-0557221820020
Pubmed

The Sjögren-Larsson syndrome gene encodes a hexadecenal dehydrogenase of the sphingosine 1-phosphate degradation pathway.

ACSL3 ACSL4

4.21e-05572222633490
Pubmed

Killer cell immunoglobulin-like receptor genotypes in Japanese patients with type 1 diabetes.

KIR3DL1 KIR3DS1

4.21e-05572217990989
Pubmed

Roles of MIWI, MILI and PLD6 in small RNA regulation in mouse growing oocytes.

PIWIL4 DICER1

6.31e-05672228115634
Pubmed

Killer cell immunoglobulin-like receptor gene polymorphism in lymphoproliferative diseases of granular lymphocytes in a Japanese population.

KIR3DL1 KIR3DS1

6.31e-05672220528243
Pubmed

Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.

PRKCD NLRP3

6.31e-05672224516390
Pubmed

Autoactivation of mouse trypsinogens is regulated by chymotrypsin C via cleavage of the autolysis loop.

CTRB2 CTRB1

6.31e-05672223814066
Pubmed

Emerging role of CCN family proteins in tumorigenesis and cancer metastasis (Review).

CCN5 CCN3

6.31e-05672226498181
Pubmed

Dicer Is Required for Normal Cerebellar Development and to Restrain Medulloblastoma Formation.

PTCH1 DICER1

8.82e-05772226091048
Pubmed

Functionally and structurally distinct NK cell receptor repertoires in the peripheral blood of two human donors.

KIR3DL1 KIR3DS1

8.82e-0577229430220
Pubmed

Ontogeny of mRNA expression and activity of long-chain acyl-CoA synthetase (ACSL) isoforms in Mus musculus heart.

ACSL3 ACSL4

8.82e-05772217197235
Pubmed

HLA-F and MHC-I Open Conformers Bind Natural Killer Cell Ig-Like Receptor KIR3DS1.

KIR3DL1 KIR3DS1

1.17e-04872227649529
Pubmed

KIR haplotype content at the allele level in 77 Northern Irish families.

KIR3DL1 KIR3DS1

1.17e-04872217200871
Pubmed

Hedgehog signaling and primary cilia are required for the formation of adult neural stem cells.

RPGRIP1 PTCH1

1.17e-04872218297065
Pubmed

Human diversity in killer cell inhibitory receptor genes.

KIR3DL1 KIR3DS1

1.17e-0487229430221
Pubmed

The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins.

ACSL3 RBBP7 BYSL ZNF622 NSUN2 METTL17 DICER1

1.40e-0454772737267103
Pubmed

Identification of eight members of the Argonaute family in the human genome.

PIWIL4 DICER1

1.51e-04972212906857
Pubmed

Alternatively spliced forms of human killer inhibitory receptors.

KIR3DL1 KIR3DS1

1.51e-0497228662091
Pubmed

Combination of KIR and HLA gene variants augments the risk of developing birdshot chorioretinopathy in HLA-A*29-positive individuals.

KIR3DL1 KIR3DS1

1.51e-04972218340360
Pubmed

Association of a common AGO1 variant with lung cancer risk: a two-stage case-control study.

PIWIL4 DICER1

1.88e-041072220721975
Pubmed

Different patterns of evolution in the centromeric and telomeric regions of group A and B haplotypes of the human killer cell Ig-like receptor locus.

KIR3DL1 KIR3DS1

1.88e-041072221206914
Pubmed

Dicer-dependent pathways regulate chondrocyte proliferation and differentiation.

PTCH1 DICER1

2.30e-041172218238902
Pubmed

Natural killer cells and immune surveillance.

KIR3DL1 KIR3DS1

2.30e-041172218830515
Pubmed

[Genotype analysis of killer cell immunoglobulin-like receptors in Graves' disease patients].

KIR3DL1 KIR3DS1

2.30e-041172219664392
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

ACSL4 EML5 NAPEPLD ACLY LRRK2 PRKCD NDRG3 CBR1 CA4

2.45e-04101672919056867
Pubmed

A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration.

JAG2 MEGF6 SACS BYSL JADE1 SSPOP METTL17

2.66e-0460872716713569
Pubmed

Association of killer cell immunoglobulin-like receptor 2DL5 with systemic lupus erythematosus and accompanying infections.

KIR3DL1 KIR3DS1

2.75e-041272220371502
Pubmed

[Polymorphism of killer cell immunoglobulin-like receptor gene and its correlation with leukemia].

KIR3DL1 KIR3DS1

2.75e-041272217490516
Pubmed

Distribution of killer cell immunoglobulin-like receptors (KIR) and their HLA-C ligands in two Iranian populations.

KIR3DL1 KIR3DS1

2.75e-041272219936734
Pubmed

Association of killer cell immunoglobulin-like receptors with primary Sjogren's syndrome.

KIR3DL1 KIR3DS1

2.75e-041272219181658
Pubmed

[Relationship between CMV reactivation and KIR haplotype/HLA-Cw genotype in patients after unrelated-donor hematopoietic stem cell transplantation.].

KIR3DL1 KIR3DS1

2.75e-041272220137308
Pubmed

Mapping a dynamic innate immunity protein interaction network regulating type I interferon production.

ACSL3 CLGN HECTD3 ZNF622 DICER1

3.09e-0428372521903422
Pubmed

Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage.

CCN5 CCN3

3.25e-041372218597638
Pubmed

KIR and HLA genotypes are associated with disease progression and survival following autologous hematopoietic stem cell transplantation for high-risk neuroblastoma.

KIR3DL1 KIR3DS1

3.25e-041372219934297
Pubmed

Different KIRs confer susceptibility and protection to adults with latent autoimmune diabetes in Latvian and Asian Indian populations.

KIR3DL1 KIR3DS1

3.25e-041372219120281
Pubmed

Defective folate metabolism causes germline epigenetic instability and distinguishes Hira as a phenotype inheritance biomarker.

PTCH1 NSUN2

3.25e-041372234140513
Pubmed

[Study on the polymorphism of killer cell immunoglobulin like receptor (KIR) gene with systemic lupus erythematosus of North population in China].

KIR3DL1 KIR3DS1

3.25e-041372218687225
Pubmed

Characterization of a novel gene, sperm-tail-associated protein (Stap), in mouse post-meiotic testicular germ cells.

CTRB2 CTRB1

3.25e-041372211468771
GeneFamilyHyalectan proteoglycans|V-set domain containing|Sushi domain containing|C-type lectin domain containing

PAPPA2 CSMD1 CR1L F13B

1.69e-05574941179
GeneFamilyCYR61/CTGF/NOV matricellular proteins

CCN5 CCN3

1.07e-0464921046
GeneFamilyCD molecules|Killer cell immunoglobulin like receptors

KIR3DL1 KIR3DS1

1.07e-0318492620
GeneFamilyPolypeptide N-acetylgalactosaminyltransferases

GALNT8 GALNT5

1.33e-0320492433
GeneFamilyAcyl-CoA synthetase family

ACSL3 ACSL4

2.24e-032649240
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT1|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL4 SLC6A11 LRRK2 GALNT5 SLC22A31

1.86e-061277155b0adbcafad31a6759c9bdce2f7f9591a8edc450
ToppCellLPS-IL1RA-Endothelial-Mes-Like-Gen_Cap|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEGF6 SACS PRSS12 ERI2 AK8

3.56e-0614571590ca38c02325c5c637c32efdef634b54cc3cd105
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 DISC1 C17orf99 PTCH1 AK8

8.18e-0617271524ecfda5e43e28f190089770cd2eae5bf2ed292b
ToppCelldroplet-Liver-LIVER-30m-Myeloid-plasmacytoid_dendritic_cells|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPGRIP1 DISC1 C17orf99 PTCH1 AK8

8.18e-06172715db5a31cafce4346fe459d7f35210823fd7004439
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MEGF6 PRSS12 ATRNL1 PTCH1 EPHA7

1.10e-051837157eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL4 EML5 LRRK2 GALNT5 SLC22A31

1.13e-05184715ab2f06906fc7a9931dfa0864ef506832b07fb93e
ToppCellfacs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l32-30|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRSS12 DISC1 KIAA0232 FAM178B LRRK2

1.26e-05188715c2febf9fd4632af1f922067c3a30e5c50f75f480
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL4 EML5 LRRK2 GALNT5 SLC22A31

1.58e-051977151485933986921ff45669d9b7501c8d17050b3e97
ToppCelllung-Type_II_Pneumocytes|lung / shred on tissue and cell subclass

ACSL4 LRRK2 GALNT5 SLC22A31

8.97e-051477148a3039de45b8087f8319e2e37329acf7278219b7
ToppCell343B-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

JAG2 CD164L2 TRBV5-1 F7

9.69e-0515071498fdc6bdfde84d680e11d8727502b79afbf64303
ToppCellE18.5-samps-Mesenchymal-Pericyte-pericyte_B|E18.5-samps / Age Group, Lineage, Cell class and subclass

C17orf99 FAM178B BYSL GALNT5

9.95e-051517148ba15ab24fe2e71df0a2a7511ca451ad2376bd91
ToppCellBrain_organoid-organoid_Kanton_Nature-Organoid-4M-Neuronal-midbrain/hindbrain_cells|Organoid-4M / Sample Type, Dataset, Time_group, and Cell type.

EML5 GALNT8 SLC38A8 TRIM60

1.07e-04154714df1b58a20af73fa79c6c069c0117a9ffd85b476f
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_3|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TIMD4 MEGF6 PRKCD PTCH1

1.21e-041597141472536eea61d4f13033efe42f128bae1614fa74
ToppCellPBMC-Severe-Myeloid-Neutrophil-Neutrophil-Neu_2|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

LRRK2 PIWIL4 CA4 SLC22A31

1.24e-04160714bb1bb3673059768c0ea0160d29fff127f3a4ecb4
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Granulocytic-Mast_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ACSL4 PRSS12 FAM178B PRKCD

1.27e-04161714c54010d88f1ecb6e0235bb66084876a4d5bf1ecd
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2-AT2_mature|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD164L2 ACSL4 FAM178B PIWIL4

1.30e-041627148e0f03fcc25b2ea777e8478fbf771699cf93719c
ToppCellE16.5-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT2|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CD164L2 ACSL4 FAM178B PIWIL4

1.30e-04162714e0417f1242edf71934fe62bccc55c4678f7ff4ac
ToppCell5'-GW_trimst-1.5-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

PTCH1 LY75 NDRG3 NLRP3

1.47e-04167714b742558ca92985db0a67c88f530bc375f3d3bb98
ToppCellfacs-Lung-EPCAM-18m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN TIMD4 LY75 SSPOP

1.64e-04172714c5caae0b21e35a2d5dcd898fbfa1ef33f92c019f
ToppCellfacs-Lung-EPCAM-18m-Myeloid-dendritic_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLGN TIMD4 LY75 SSPOP

1.64e-041727147c085c02b59e24e2a2cd393b5e692f9fb19257fe
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(Ndrg2)|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GALNT5 AK8 F13B

1.83e-04697133f6902cb62d6130b3d3a1cf122dbc695f7349ffe
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Ndrg2_(Ndrg2)-|Entopeduncular / BrainAtlas - Mouse McCarroll V32

GALNT5 AK8 F13B

1.83e-0469713832ed163f553481b49bbf8a1eb10cbd8afab4e34
ToppCellBAL-Mild-cDC_4|Mild / Compartment, Disease Groups and Clusters

NAPEPLD AZIN2 KIAA0232 LRRK2

1.91e-0417971468511e87b12b8253de7771e5ccfc5869248b8450
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL4 LRRK2 GALNT5 SLC22A31

1.91e-04179714fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellLPS-IL1RA-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

PRSS12 ATRNL1 PTCH1 EPHA7

1.91e-0417971402c90d8306016365ed811f0c63cfb3ac7b85464c
ToppCellASK454-Endothelial-Lymphatic|ASK454 / Donor, Lineage and Cell class of Lung cells from Dropseq

CCN5 RPGRIP1 NAPEPLD PEAR1

1.91e-04179714fd84a79f76a01c0377dff5b20016b004d369f96f
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

C17orf99 FAM178B GALNT5 CR1L

2.08e-041837141db466cf757813322db1cdcc0bf1d91c062fd9de
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 LRRK2 CA4

2.12e-04184714d33de57876817050b294f2ecb0a4eb0634cfa7f0
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 LRRK2 CA4

2.12e-041847148fd8bd3d28d0ee6f0ef1f14e354d8eaf63a8081b
ToppCellControl-Epithelial_alveolar-AT_2-Differentiating_AT2|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL4 LRRK2 GALNT5 SLC22A31

2.17e-041857140d2add28ac1f4fa6de7699be009bf8391badaf4c
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 LRRK2 CA4

2.17e-0418571474b787e225d83efcb84e79c23499febe1a106622
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL4 LRRK2 GALNT5 SLC22A31

2.21e-04186714e83718fabb057100835d3357df407f283d23fe16
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Inhba_(CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC7A9 GALNT5 SLC38A8

2.25e-047471329d94713d97ac44e0f83d2f3609a719650e20d0f
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ACSL4 LRRK2 GALNT5 SLC22A31

2.31e-041887144bdf8d49af0e9da349b16e3f012e1b0eec04cc4f
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Lobular_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

MEGF6 AZIN2 NLRP3 PEAR1

2.31e-04188714c90669b51e1902fe7726555290c91c92a911df83
ToppCell15-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

C17orf99 FAM178B CR1L F7

2.31e-04188714c68ccb1c5c21d13ddac09b16e7d466f0530bbda5
ToppCell15-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

C17orf99 FAM178B CR1L F7

2.31e-041887142534684e4932c1255c24a26ca2277ac7af0a118b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 LRRK2 CA4

2.35e-04189714e059be2965cca70ff5576df055d0af1775b76e00
ToppCellAT2_cells-Cryobiopsy_01|World / lung cells shred on cell class, cell subclass, sample id

MEGF6 LRRK2 GALNT5 SLC22A31

2.35e-041897142d32f09efa982ae458568f6b1cd06bb5078d42a3
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 CCN3 CA4

2.40e-04190714498bbe063bc75d323cb186a82cce122b511d2cff
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PIWIL4 GALNT5 SSPOP

2.44e-0476713efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PIWIL4 GALNT5 SSPOP

2.44e-0476713254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCellMyeloid-Myeloid-B_(Activated_Macrophage)|Myeloid / shred on cell class and cell subclass (v4)

ACSL4 LY75 F7 CA4

2.45e-041917147bf125249af1e8bb138ed4d999fdd74b03ab2447
ToppCellproximal-Hematologic-Platelet/Megakaryocyte|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DISC1 C17orf99 FAM178B PIWIL4

2.50e-04192714522d1bb15edf1d6006b80289bd3baadb99584ae8
ToppCellproximal-3-Hematologic-Platelet/Megakaryocyte|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DISC1 C17orf99 FAM178B PIWIL4

2.50e-04192714f5f83dec37dff32a0c471cb05d23d13b0b0ad0c9
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

ACSL4 MEGF6 LRRK2 SLC22A31

2.50e-04192714cc9911e182a289779a2612bc213daae5607689e7
ToppCellproximal-Hematologic-Platelet/Megakaryocyte-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

DISC1 C17orf99 FAM178B PIWIL4

2.50e-0419271457899a905ca3e336bb7f31edc6418a2546b9891a
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nts|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

C17orf99 GALNT5 LY75

2.53e-0477713dbbefd2dfa4c345172cb5a995952e3682fbadf92
ToppCellCOPD-Myeloid-Macrophage|World / Disease state, Lineage and Cell class

ACSL3 LRRK2 CSMD1 NLRP3

2.60e-041947147d682408e9a6239a4e47befc9376e760cc3d133a
ToppCellTCGA-Thryoid-Primary_Tumor|TCGA-Thryoid / Sample_Type by Project: Shred V9

JAG2 HECTD3 LRRK2 SLC22A31

2.65e-041957147cdee2ae90edf15e4cbcf70797b8caf1f037b0ef
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma|TCGA-Thryoid / Sample_Type by Project: Shred V9

JAG2 HECTD3 LRRK2 SLC22A31

2.65e-04195714b61b8c931bd0ca3678486653ae1d7e9915c696c7
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 CCN3 CA4

2.70e-04196714d688350aadc622984d612ae6b2fd7c0113a4ec0f
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

EML5 GALNT5 AK8 SLC22A31

2.75e-04197714b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2-AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.75e-04197714ad6f047d003c08413264f39a30ba0f7639a257cd
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.75e-041977141a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.75e-041977141638959d7aecb9fc5285eb7e4a3103ca437989e2
ToppCellLPS_only-Epithelial_alveolar-AT_2|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-04198714d087e738d69ca9853553fde46d4e7a8906439d32
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 CBR1 CA4

2.81e-04198714688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ACSL4 MEGF6 LRRK2 SLC22A31

2.81e-0419871485215015bb86ada0e871c413a4ecdc903a3785ca
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-04198714285f729140b1df029c24f6ca1d2438470ac51794
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PAPPA2 ACSL4 CBR1 CA4

2.81e-041987144448d13511485a44fe7b549e4b8b6ad7637db624
ToppCellLPS_only-Hematopoietic_Myeloid-Dendritic_cells-pDC|LPS_only / Treatment groups by lineage, cell group, cell type

FAM178B PRKCD JADE1 EPHA7

2.81e-04198714d205dfcfe1f20e1e21bf84759e723d9e6e610a5c
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2-AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-04198714d12f37527399038a8f030b45b176bda5c7c8a7ad
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-04198714c4e7512f0e1d115f2be8acae6048eda8b6b640b2
ToppCellLPS_anti-TNF-Epithelial_alveolar|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-0419871453e9ed1b19cb26be58da0f37057caca0cdfaabeb
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-04198714aa80315395cb5dffc25927c8a77cd2037aea8772
ToppCellLPS_only-Epithelial_alveolar|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-04198714655df75b9692d815c7f6910275e1f684ac63bf62
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.81e-0419871482bcd44f8744e7e8477fbfd871a52f3d1a8b3adc
ToppCell367C-Epithelial_cells-Epithelial-E_(AT2)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

ACSL4 MEGF6 LRRK2 SLC22A31

2.81e-0419871438349e42a3f1fb700ff6dfd89c4bf5ff97f1a3e9
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Man1a_(Man1a)|Hippocampus / BrainAtlas - Mouse McCarroll V32

GALNT5 SSPOP F7

2.84e-0480713d42b72ef822f731ff5ff1d04216e91f414c5556e
ToppCellHippocampus-Macroglia-OLIGODENDROCYTE-O2-Trf-Oligodendrocyte.Trf.Man1a_(Man1a)-|Hippocampus / BrainAtlas - Mouse McCarroll V32

GALNT5 SSPOP F7

2.84e-0480713d3ee8fc9b2cb47ee476f4cd8b9fcba14cb9ca759
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.86e-041997143a0af1a13b1760f4213d87d0958dbe3bf3b9a42b
ToppCellLPS_IL1RA-Epithelial_alveolar|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.86e-041997145b140ac88ebc25ce397ae577e48f3e271faf46e7
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRSS12 ATRNL1 PTCH1 EPHA7

2.86e-04199714e9820d5fb4e8b46973c4c50ac5db8fb4a1bf603b
ToppCellBiopsy_IPF-Epithelial-Transitional_AT2|Biopsy_IPF / Sample group, Lineage and Cell type

MEGF6 LRRK2 GALNT5 SLC22A31

2.86e-0419971483ff8b7e472d1212324c05cc719b746d19e5e23b
ToppCellLPS_anti-TNF-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

PRSS12 ATRNL1 PTCH1 EPHA7

2.86e-0419971438cfd367ee8c074c11ba54edeb7a001e375e2687
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor-Progenitor_AT1-AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.86e-041997140447f8f53389fe7c6ddc04a97d86e74122ea16f4
ToppCellLPS_only-Epithelial_alveolar-AT_1-2_Progenitor-AT2_Progenitor|LPS_only / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.86e-041997147b21447bb39cdba37539a12cb475f463010fc23f
ToppCell5'-Parenchyma_lung-Epithelial-Alveolar_epithelium-type_II_pneumocyte-AT2-AT2_L.0.1.3.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ACSL4 MEGF6 LRRK2 SLC22A31

2.86e-041997142dc33804f6691d7c9682e6c9b885e945fb97fc36
ToppCellLPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type

ACSL4 LRRK2 GALNT5 SLC22A31

2.92e-04200714e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCellLPS_IL1RA-Mesenchymal_myocytic-Myofibroblastic|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

PAPPA2 PRSS12 ATRNL1 PTCH1

2.92e-0420071487827041663013f5e7273168dc8709d69840e7ce
ToppCellControl_saline-Mesenchymal_myocytic-Myofibroblastic-MatrixFB_->_Myofibroblast|Control_saline / Treatment groups by lineage, cell group, cell type

PRSS12 ATRNL1 PTCH1 EPHA7

2.92e-04200714a799fc7bb83ad0524362cb5010df949741fb7bf3
ToppCellControl_saline-Epithelial_alveolar-AT_1-Differentiating_AT2|Control_saline / Treatment groups by lineage, cell group, cell type

EML5 KIAA0232 GALNT5 SLC22A31

2.92e-04200714eac33be484dc443794e66e473f03e98406c2983e
Drugc189

CTRB2 CTRB1

9.32e-062702CID000248048
DrugBOCPheONP

CTRB2 CTRB1

9.32e-062702CID000111308
Drugdansyl-D-arginine methyl ester

CTRB2 CTRB1

9.32e-062702CID000191369
DrugMPM-06

CTRB2 CTRB1

9.32e-062702CID000161546
Drugmethyl 6-phenylhexanoate

CTRB2 CTRB1

9.32e-062702CID011820300
DrugNSC-374899

CTRB2 CTRB1

9.32e-062702CID000435726
Drug5-aminotetrazole

CTRB2 CTRB1

9.32e-062702CID000020467
Drug2-bromoisobutyric acid

CTRB2 CTRB1

9.32e-062702CID000074924
Drugp-toluamidine

CTRB2 CTRB1

9.32e-062702CID000122753
Drugmethylbenzenebutanoate

CTRB2 CTRB1

9.32e-062702CID000281254
DrugN-acetyl-alpha-azaphenylalanine phenyl ester

CTRB2 CTRB1

9.32e-062702CID000191275
DrugAsp-Arg-Val-Tyr-Val-His-Pro-Phe-His-Leu

CTRB2 CTRB1

9.32e-062702CID004418081
Drugisobutyl sulfide

CTRB2 CTRB1

9.32e-062702CID000011607
DrugzLYCK

NAPEPLD CTRB2 CTRB1

1.51e-0516703CID000171556
Drugmethylcyclopentadienyl manganese tricarbonyl

CTRB2 PRKCD CTRB1

1.83e-0517703CID000025511
Drug3-amino-2-pyridone

CTRB2 CTRB1

2.79e-053702CID000322353
DrugASA-BMPA

CTRB2 CTRB1

2.79e-053702CID003035649
Drugp-nitrophenyl benzoate

CTRB2 CTRB1

2.79e-053702CID000070396
DrugN-acetylbenzotriazole

CTRB2 CTRB1

2.79e-053702CID000087784
DrugZ-Phe-OMe

CTRB2 CTRB1

2.79e-053702CID003082435
Drugphotophor

CTRB2 CTRB1

2.79e-053702CID000014780
Drug3-methylcoumarin

CTRB2 CTRB1

2.79e-053702CID000017130
Drugdibutyl iodomethaneboronate

CTRB2 CTRB1

2.79e-053702CID000098591
Drugzinc;dipicolinate

CTRB2 CTRB1

2.79e-053702CID004309911
Drug2-propyl methylphosphonochloridate

CTRB2 CTRB1

2.79e-053702CID000102124
Drug2-oxobut-3-ynoate

CTRB2 CTRB1

2.79e-053702CID000171547
DrugAFMeq

CTRB2 CTRB1

2.79e-053702CID000194069
DrugBz-Cti-otbu

CTRB2 CTRB1

2.79e-053702CID006452691
Drugn-(2-oxoethyl)benzamide

CTRB2 CTRB1

2.79e-053702CID000188995
DrugAC1L49DM

CTRB2 CTRB1

2.79e-053702CID000152933
DrugFK-316

CTRB2 CTRB1

2.79e-053702CID000133688
DrugAC1L19T8

CTRB2 CTRB1

2.79e-053702CID000000694
DrugMarinostatin D

CTRB2 CTRB1

2.79e-053702CID000132206
Drugc140

CTRB2 CTRB1

2.79e-053702CID002783250
Drug1FD7

CTRB2 CTRB1

2.79e-053702CID000445579
DrugBenzamidomethaneboronic acid

CTRB2 CTRB1

2.79e-053702CID000127677
Drugphenyl hippurate

CTRB2 CTRB1

2.79e-053702CID000076323
DrugFK-386

CTRB2 CTRB1

2.79e-053702CID000135044
DrugFK-375

CTRB2 CTRB1

2.79e-053702CID000135042
Drugcarbostyril-124

CTRB2 CTRB1

2.79e-053702CID000088277
DrugN-trifluoroacetyl-4-fluorophenylalanine

CTRB2 CTRB1

2.79e-053702CID000328214
DrugGlt-leu-phe-nh-meq

CTRB2 CTRB1

2.79e-053702CID000194914
DrugAC1L4Z4F

CTRB2 CTRB1

2.79e-053702CID000194913
DrugGlt-Phe-NH-FMeq

CTRB2 CTRB1

2.79e-053702CID000194912
DrugC18 4

CTRB2 CTRB1

2.79e-053702CID000077248
Drugdiacetyl trimer

CTRB2 CTRB1

2.79e-053702CID000193527
DrugFK-448

CTRB2 CTRB1

2.79e-053702CID006917869
DrugAc-Phe-OMe

CTRB2 CTRB1

2.79e-053702CID000097805
Drugtaraxastane

CTRB2 CTRB1

2.79e-053702CID006429404
Drugthiobenzyl N-heptafluorobutyrylanthranilate

CTRB2 CTRB1

2.79e-053702CID000133906
DrugPhe-phe-ome

CTRB2 CTRB1

2.79e-053702CID000151728
Drugphenylethaneboronic acid

CTRB2 CTRB1

2.79e-053702CID000065389
DrugF-Ct

CTRB2 CTRB1 CBR1

3.06e-0520703CID000445968
DrugAC1NRB18

CTRB2 CTRB1 CBR1

3.56e-0521703CID005288203
DrugBenzoyl-dl-leucine

CTRB2 CTRB1

5.57e-054702CID000294887
DrugAcafcek

CTRB2 CTRB1

5.57e-054702CID000197677
Drugp-fluorobenzenesulfonyl chloride

CTRB2 CTRB1

5.57e-054702CID000009588
DrugBSSDA

CTRB2 CTRB1

5.57e-054702CID003081106
DrugB-1,3-od

CTRB2 CTRB1

5.57e-054702CID011971053
DrugAC1L2HV6

CTRB2 CTRB1

5.57e-054702CID000047328
Drugdehydromerodesmosine

CTRB2 CTRB1

5.57e-054702CID006443540
DrugAC1L4X1Z

CTRB2 CTRB1

5.57e-054702CID000193815
Drugalpha-amyrin palmitate

CTRB2 CTRB1

5.57e-054702CID000185477
Drugpoly-THIQ

CTRB2 CTRB1

5.57e-054702CID006453487
DrugNSC-676827

CTRB2 CTRB1

5.57e-054702CID000385555
DrugN-(4-carboxycyclohexylmethyl)-maleimide

CTRB2 CTRB1

5.57e-054702CID011548799
DrugG2505_sigma

CTRB2 CTRB1

5.57e-054702CID000111098
Drug6-amino-1,2-benzopyrone

CTRB2 CTRB1

5.57e-054702CID000046152
Drugnitrophenylethanol

CTRB2 CTRB1

5.57e-054702CID000097851
Drug7-chloro-4-nitrobenzofuran

CTRB2 CTRB1

9.26e-055702CID000130782
DrugAc-Trp-OEt

CTRB2 CTRB1

9.26e-055702CID000304749
DrugZ-Phe-Leu

CTRB2 CTRB1

9.26e-055702CID000333351
Drug5'-FSBAzA

CTRB2 CTRB1

9.26e-055702CID000130430
DrugAC1L3F57

CTRB2 CTRB1

9.26e-055702CID000139565
Drugapne

CTRB2 CTRB1

9.26e-055702CID000098192
Drug3,5-dimethylpyrazole-1-carboxamidine

CTRB2 CTRB1

9.26e-055702CID000097525
DrugMaap-borov

CTRB2 CTRB1

9.26e-055702CID005486914
Drug2-amino-4,6-dichlorotriazine

CTRB2 CTRB1

9.26e-055702CID000013615
DrugAC1O52A0

CTRB2 CTRB1

9.26e-055702CID006475891
Drugallysine aldol

CTRB2 CTRB1

9.26e-055702CID000191270
Drugmangrove

ACSL3 ACSL4 NAPEPLD CTRB2 PRKCD PTCH1 CTRB1 F7

9.28e-05468708CID000000965
Drugoctyl isocyanate

CTRB2 CTRB1

1.39e-046702CID000076616
DrugAsp-Asp-Asp-Asp

CTRB2 CTRB1

1.39e-046702CID004432006
DrugN-benzoyl-L-tyrosine thiobenzyl ester

CTRB2 CTRB1

1.39e-046702CID000191444
DrugLeupeptin acid

CTRB2 CTRB1

1.39e-046702CID000189069
DrugSri 8835

CTRB2 CTRB1

1.39e-046702CID000479975
DrugN,N-dimethylglycylbenzocaine

CTRB2 CTRB1

1.39e-046702CID000188251
DrugN-benzoyltyrosine butylamide

CTRB2 CTRB1

1.39e-046702CID000125261
DrugD-gluconyl-glycine azide

CTRB2 CTRB1

1.39e-046702CID000194550
Drug2-azidoatrazine

CTRB2 CTRB1

1.39e-046702CID003032432
DrugL-659,286

CTRB2 CTRB1

1.39e-046702CID000128954
Drugbz-Ala-OMe

CTRB2 CTRB1

1.39e-046702CID000023671
DrugFK480

CTRB2 CTRB1

1.39e-046702CID000132916
DrugMaap-borof

CTRB2 CTRB1

1.39e-046702CID005492190
DrugAC1L4DZ7

CTRB2 CTRB1

1.39e-046702CID000155288
Drugcobalt;(6E)-6-[[2-[[(E)-(6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]ethylamino]methylene]cyclohexa-2,4-dien-1-one;hydrate

CTRB2 CTRB1

1.39e-046702CID011810022
Drugsoman

CTRB2 PRKCD CTRB1 CA4

1.87e-0492704CID000007305
Drugdinonylnaphthalene

CTRB2 CTRB1

1.94e-047702CID003015220
Drugm-aminobenzamidine

CTRB2 CTRB1

1.94e-047702CID000197789
Drugmethyl p-nitrobenzenesulfonate

CTRB2 CTRB1

1.94e-047702CID000022582
Diseaselevel of chymotrypsinogen B2 in blood serum

CTRB2 CTRB1

5.39e-062692OBA_2041192
Diseasenon-syndromic X-linked intellectual disability 63 (implicated_via_orthology)

ACSL3 ACSL4

5.39e-062692DOID:0112050 (implicated_via_orthology)
Diseasechymotrypsinogen B measurement

CTRB2 CTRB1

1.61e-053692EFO_0801477
Diseasechronic fatigue syndrome (is_implicated_in)

DISC1 KIR3DS1

5.36e-055692DOID:8544 (is_implicated_in)
DiseaseSjogren-Larsson syndrome (implicated_via_orthology)

ACSL3 ACSL4

8.03e-056692DOID:14501 (implicated_via_orthology)
Diseasemetachronous colorectal adenoma

SLC6A11 NLRP3 EPHA7

1.62e-0445693EFO_0803377
Diseasenon-syndromic X-linked intellectual disability (implicated_via_orthology)

ACSL3 ACSL4

1.92e-049692DOID:0050776 (implicated_via_orthology)
DiseaseNG-monomethyl-arginine measurement

SLC7A9 CSMD1

2.92e-0411692EFO_0010510
DiseaseBasal cell carcinoma

XPC PTCH1

2.92e-0411692C0007117
Diseasetrypsin-2 measurement

CTRB2 CTRB1

2.92e-0411692EFO_0008305
Diseaseantisaccade response measurement

DISC1 GALNT8 CSMD1

3.10e-0456693EFO_0006874
DiseaseOligospermia

PIWIL4 DICER1

3.50e-0412692C0028960
Diseasehyperglycemia (is_marker_for)

PTCH1 F7

4.13e-0413692DOID:4195 (is_marker_for)
DiseaseRhabdomyosarcoma

PTCH1 DICER1

5.55e-0415692C0035412
Diseasethyroid peroxidase antibody measurement

ATRNL1 DICER1 TRIM60

6.50e-0472693EFO_0005666
Diseasecortical thickness change measurement

CSMD1 EPHA7

8.05e-0418692EFO_0021501
DiseaseHemorrhage

F7 EPHA7

9.96e-0420692C0019080
DiseaseDeep Vein Thrombosis

F7 F13B

1.10e-0321692C0149871
DiseaseVenous Thrombosis

F7 F13B

1.10e-0321692C0042487
Diseasemalaria (is_implicated_in)

KIR3DL1 KIR3DS1

1.44e-0324692DOID:12365 (is_implicated_in)
DiseaseAutosomal Dominant Parkinsonism

LRRK2 PRKCD

1.96e-0328692C0752098
DiseaseAutosomal Dominant Juvenile Parkinson Disease

LRRK2 PRKCD

1.96e-0328692C0752097
Diseasehepatitis C (is_implicated_in)

KIR3DL1 KIR3DS1

1.96e-0328692DOID:1883 (is_implicated_in)
DiseaseParkinsonism, Experimental

LRRK2 PRKCD

1.96e-0328692C0752101
DiseaseAutosomal Recessive Parkinsonism

LRRK2 PRKCD

1.96e-0328692C0752100
DiseaseFamilial Juvenile Parkinsonism

LRRK2 PRKCD

1.96e-0328692C0752104
DiseaseRamsay Hunt Paralysis Syndrome

LRRK2 PRKCD

1.96e-0328692C0242423
DiseasePARKINSON DISEASE 2, AUTOSOMAL RECESSIVE JUVENILE

LRRK2 PRKCD

1.96e-0328692C1868675
Diseasetuberculosis (is_implicated_in)

KIR3DL1 KIR3DS1

1.96e-0328692DOID:399 (is_implicated_in)
DiseaseStrabismus

RPGRIP1 CSMD1

2.10e-0329692HP_0000486
DiseaseParkinsonism, Juvenile

LRRK2 PRKCD

2.25e-0330692C0752105
DiseaseParkinsonian Disorders

LRRK2 PRKCD

2.25e-0330692C0242422
Diseaseintellectual disability (is_implicated_in)

ACSL4 PRSS12

2.25e-0330692DOID:1059 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
PLICCEIKLKDWQEG

ACSL4

491

O60488
PLVCQKDGAWTLVGI

CTRB2

216

Q6GPI1
EGVPLKICLSQFCKW

ERI2

106

A8K979
DCKVPGDDCPLVWGQ

ANAPC11

36

Q9NYG5
GVWKGEIPQCLPVFC

CSMD1

3141

Q96PZ7
VEGVCKPLSCGWEIT

AZIN2

431

Q96A70
CRAVLVVLGPWCADK

DICER1

306

Q9UPY3
SCKCPLLGKVWEADL

DISC1

681

Q9NRI5
LQCPIVLCGWRGKAS

NSUN2

671

Q08J23
EGLVLINVDPCAKGW

NDRG3

156

Q9UGV2
EGGWACLVCKEKLII

NUP133

111

Q8WUM0
ILLCEKDIWQGGVCP

PRSS12

246

P56730
GKFCIILVCVCWVGG

OR11H6

156

Q8NGC7
LWGLVKQGLKCEDCG

PRKCD

251

Q05655
KCPGSLHIIRWIQGC

HORMAD2

76

Q8N7B1
CGWKPCLLAGQPEAL

JAG2

906

Q9Y219
KLQDLPPCWGLDIVC

KIAA1109

321

Q2LD37
GPLVKSGERVILQCW

KIR3DL1

131

P43629
CEDGKWTEPPKCIEG

F13B

316

P05160
CIKQGWILDGIPETR

AK8

131

Q96MA6
LGPVQTWLGQELEKC

KIAA0232

36

Q92628
EILKCIEECVEPWNG

PGM2L1

201

Q6PCE3
PIDGECVCKEGWQRG

PEAR1

461

Q5VY43
GWSLLCKLIEVCPGT

LRRK2

81

Q5S007
ACDTKLEWVCQIPKG

LY75

781

O60449
SAEGEWLVPIGKCIC

EPHA7

251

Q15375
VCLWDINAGPKEGKI

RBBP7

201

Q16576
KIQCLEGGIWEQGSC

PAPPA2

1576

Q9BXP8
LEVFPKGRWVLITCC

C17orf99

36

Q6UX52
CLVPVKWGGNCQKDR

CA4

36

P22748
VEVPGECCEKWICGP

CCN3

161

P48745
LIKCGEWCIAPIPDK

GALNT5

851

Q7Z7M9
RVWQCGGKVEILPCS

GALNT8

391

Q9NY28
AVGPCLIIWAACGVL

SLC7A9

61

P82251
WDNKTPVCDRIICGL

CR1L

146

Q2VPA4
VEVLGKCCPEWVCGQ

CCN5

151

O76076
EELCKNAGPGIKCVW

ATRNL1

621

Q5VV63
RKGDKILLNACCPGW

CBR1

216

P16152
IWPAVQGACKQLEVC

CD164L2

46

Q6UWJ8
TSVLGLCCEGIWPVI

EML5

1176

Q05BV3
LCCEGIWPVIGEVTD

EML5

1181

Q05BV3
IKIWPIGREINCKCL

FBXW2

301

Q9UKT8
LVCGDGWKVPLEQVS

SLC22A31

121

A6NKX4
LVWKGDLCNLCAPPD

SACS

1171

Q9NZJ4
KCLLTLGRWCPGLGV

METTL17

6

Q9H7H0
WFKGILIPLCESGTC

BYSL

286

Q13895
PLVCQKDGAWTLVGI

CTRB1

216

P17538
CIVVEGPILDCWTCL

IZUMO3

136

Q5VZ72
IPLVCWIVCTGLKQQ

NLRP3

411

Q96P20
GWAGLACEKECLPRD

MEGF6

1066

O75095
EPQNELWIEITKCCG

RPGRIP1

796

Q96KN7
CPCLVGEELKWPGVS

SSPOP

2676

A2VEC9
GKVCPKGECPWQVLL

F7

216

P08709
KGECPWQVLLLVNGA

F7

221

P08709
NIREWPGKLQELCCT

FAM178B

481

Q8IXR5
GPLVKSGERVILQCW

KIR3DS1

131

Q14943
CKLGGELWAVEIPLK

PIWIL4

601

Q7Z3Z4
CLIITPLDCFWEGAK

PTCH1

226

Q13635
GILKVPEGSWLCRTC

JADE1

236

Q6IE81
GPRVKCCLEVWGVVS

SLC38A8

401

A6NNN8
IKEGRLTKPIVCWCI

ACLY

731

P53396
LVCCEIKLKNWEEGG

ACSL3

501

O95573
ILNPACRIGCGEWKP

CLGN

346

O14967
REEPVWLEGTKLCCQ

RNF223

131

E7ERA6
EGGITCWRKVCPLFE

SLC6A11

116

P48066
LCWVLLCPLGEGPVD

TRBV5-7

6

A0A0A0MS05
VGNKPKWILGVCQDC

TRIM60

356

Q495X7
LCWVLLCLLGAGPVK

TRBV5-1

6

A0A578
LCQCKKGVDPIGWIS

ZNF226

196

Q9NYT6
VVIRGLCGEQPMCWE

VWA5B2

841

Q8N398
GEKVGVGKICLWCNE

ZNF622

296

Q969S3
KWVCVDCVHGVVGQP

XPC

541

Q01831
CCRIEVPGWFNDVKI

TIMD4

111

Q96H15
GDCGLQEGWLLVCRP

HECTD3

131

Q5T447
VPLGLLDWMQKCGCE

NAPEPLD

211

Q6IQ20