Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	linoleic acid epoxygenase activity	CYP2C19 CYP2C9 CYP2C18	8.75e-06	4	261	3	GO:0071614
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	AVPR1A GALR2 GPR171 NTSR1 GPR139 EDNRB OPRD1 OPRK1 OPRM1	6.45e-05	133	261	9	GO:0008528
GeneOntologyMolecularFunction	G protein-coupled opioid receptor activity	OPRD1 OPRK1 OPRM1	7.43e-05	7	261	3	GO:0004985
GeneOntologyMolecularFunction	ubiquitin-like protein peptidase activity	USP11 USP25 SENP1 USP7 USP15 USP47 USP49 PRPF8 USP6	8.11e-05	137	261	9	GO:0019783
GeneOntologyMolecularFunction	peptide receptor activity	AVPR1A GALR2 GPR171 NTSR1 GPR139 EDNRB OPRD1 OPRK1 OPRM1	9.59e-05	140	261	9	GO:0001653
GeneOntologyMolecularFunction	neuropeptide binding	GALR2 GPR171 OPRD1 OPRK1 OPRM1	1.14e-04	37	261	5	GO:0042923
GeneOntologyMolecularFunction	(R)-limonene 6-monooxygenase activity	CYP2C19 CYP2C9	1.70e-04	2	261	2	GO:0052741
GeneOntologyMolecularFunction	(S)-limonene 6-monooxygenase activity	CYP2C19 CYP2C9	1.70e-04	2	261	2	GO:0018675
GeneOntologyMolecularFunction	(S)-limonene 7-monooxygenase activity	CYP2C19 CYP2C9	1.70e-04	2	261	2	GO:0018676
GeneOntologyMolecularFunction	limonene monooxygenase activity	CYP2C19 CYP2C9	1.70e-04	2	261	2	GO:0019113
GeneOntologyMolecularFunction	UDP-D-xylose:beta-D-glucoside alpha-1,3-D-xylosyltransferase activity	GXYLT1 GXYLT2	1.70e-04	2	261	2	GO:0140563
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	IL13RA2 OR5AK2 TRHR AVPR1A OR2G3 TMEM63B TNFRSF11A PTAFR IL18RAP GALR2 CHRNA1 NRP2 OR1N2 ADORA1 PTPRK PTPRM OR4K1 GPR171 OR8D4 OR52B2 PLXNA2 IL17RB OR2AG1 OR4K2 NTSR1 OR5M11 GPR139 EDNRB OPRD1 OPRK1 OPRM1 OR4K3 IL5RA OR4F6	1.89e-04	1353	261	34	GO:0004888
GeneOntologyMolecularFunction	deubiquitinase activity	USP11 USP25 USP7 USP15 USP47 USP49 PRPF8 USP6	2.28e-04	124	261	8	GO:0101005
GeneOntologyMolecularFunction	neuropeptide receptor activity	GALR2 GPR171 NTSR1 GPR139 OPRM1	6.31e-04	53	261	5	GO:0008188
GeneOntologyMolecularFunction	retinoic acid 4-hydroxylase activity	CYP2C19 CYP2C9 CYP2C18	7.22e-04	14	261	3	GO:0008401
GeneOntologyMolecularFunction	cysteine-type deubiquitinase activity	USP11 USP25 USP7 USP15 USP47 USP49 USP6	7.54e-04	114	261	7	GO:0004843
GeneOntologyMolecularFunction	cysteine-type endopeptidase activity	USP11 SENP1 USP7 USP15 USP49 USP6	9.24e-04	86	261	6	GO:0004197
GeneOntologyMolecularFunction	arachidonate 11,12-epoxygenase activity	CYP2C19 CYP2C9	1.00e-03	4	261	2	GO:0008405
Domain	USP_C	USP11 USP7 USP15	2.76e-06	3	263	3	IPR029346
Domain	USP7_C2	USP11 USP7 USP15	2.76e-06	3	263	3	PF14533
Domain	Opioid_rcpt	OPRD1 OPRK1 OPRM1	1.09e-05	4	263	3	IPR001418
Domain	USP_CS	USP11 USP25 USP7 USP15 USP47 USP49 USP6	3.89e-05	66	263	7	IPR018200
Domain	DUF3398	DOCK6 DOCK9 DOCK7	5.35e-05	6	263	3	PF11878
Domain	DOCK_C/D_N	DOCK6 DOCK9 DOCK7	5.35e-05	6	263	3	IPR021816
Domain	USP_1	USP11 USP25 USP7 USP15 USP47 USP49 USP6	5.70e-05	70	263	7	PS00972
Domain	UCH	USP11 USP25 USP7 USP15 USP47 USP49 USP6	6.25e-05	71	263	7	PF00443
Domain	USP_2	USP11 USP25 USP7 USP15 USP47 USP49 USP6	6.25e-05	71	263	7	PS00973
Domain	USP_dom	USP11 USP25 USP7 USP15 USP47 USP49 USP6	6.84e-05	72	263	7	IPR028889
Domain	Peptidase_C19_UCH	USP11 USP25 USP7 USP15 USP47 USP49 USP6	6.84e-05	72	263	7	IPR001394
Domain	USP_3	USP11 USP25 USP7 USP15 USP47 USP49 USP6	6.84e-05	72	263	7	PS50235
Domain	GPCR_Rhodpsn_7TM	OR5AK2 TRHR AVPR1A OR2G3 PTAFR GALR2 OR1N2 ADORA1 OR4K1 GPR171 OR8D4 OR52B2 OR2AG1 OR4K2 NTSR1 OR5M11 GPR139 EDNRB OPRD1 OPRK1 OPRM1 OR4F6	2.15e-04	670	263	22	IPR017452
Domain	7tm_1	OR5AK2 TRHR AVPR1A OR2G3 PTAFR GALR2 OR1N2 ADORA1 OR4K1 GPR171 OR8D4 OR52B2 OR2AG1 OR4K2 NTSR1 OR5M11 GPR139 EDNRB OPRD1 OPRK1 OPRM1 OR4F6	2.48e-04	677	263	22	PF00001
Domain	PAS_fold_3	KCNH8 NPAS3 PER3 KCNH4	2.76e-04	23	263	4	IPR013655
Domain	PAS_3	KCNH8 NPAS3 PER3 KCNH4	2.76e-04	23	263	4	PF08447
Domain	G_PROTEIN_RECEP_F1_1	OR5AK2 TRHR AVPR1A OR2G3 PTAFR GALR2 OR1N2 ADORA1 OR4K1 GPR171 OR8D4 OR52B2 OR2AG1 OR4K2 NTSR1 OR5M11 GPR139 EDNRB OPRD1 OPRK1 OPRM1 OR4F6	2.92e-04	685	263	22	PS00237
Domain	PAS-assoc_C	KCNH8 NPAS3 PER3 KCNH4	3.27e-04	24	263	4	IPR000700
Domain	G_PROTEIN_RECEP_F1_2	OR5AK2 TRHR AVPR1A OR2G3 PTAFR GALR2 OR1N2 ADORA1 OR4K1 GPR171 OR8D4 OR52B2 OR2AG1 OR4K2 NTSR1 OR5M11 GPR139 EDNRB OPRD1 OPRK1 OPRM1 OR4F6	3.29e-04	691	263	22	PS50262
Domain	GPCR_Rhodpsn	OR5AK2 TRHR AVPR1A OR2G3 PTAFR GALR2 OR1N2 ADORA1 OR4K1 GPR171 OR8D4 OR52B2 OR2AG1 OR4K2 NTSR1 OR5M11 GPR139 EDNRB OPRD1 OPRK1 OPRM1 OR4F6	3.36e-04	692	263	22	IPR000276
Domain	DOCK	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	IPR026791
Domain	DOCK_C	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	IPR010703
Domain	DOCK-C2	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	PF14429
Domain	DHR-1_domain	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	IPR027007
Domain	DHR_2	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	PS51651
Domain	DHR_1	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	PS51650
Domain	DHR-2	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	PF06920
Domain	DHR-2	DOCK6 DOCK9 DOCK7	4.19e-04	11	263	3	IPR027357
Domain	PAC	KCNH8 NPAS3 PER3 KCNH4	4.50e-04	26	263	4	PS50113
Domain	PAC	KCNH8 NPAS3 PER3 KCNH4	4.50e-04	26	263	4	SM00086
Domain	PAC	KCNH8 NPAS3 PER3 KCNH4	4.50e-04	26	263	4	IPR001610
Domain	Cornichon_conserved	CNIH3 CNIH2	5.87e-04	3	263	2	IPR033466
Domain	K_chnl_volt-dep_ELK	KCNH8 KCNH4	5.87e-04	3	263	2	IPR003950
Domain	CORNICHON	CNIH3 CNIH2	5.87e-04	3	263	2	PS01340
Domain	CNMP_BINDING_1	KCNH8 SLC9C1 SLC9C2 KCNH4	1.01e-03	32	263	4	PS00888
Domain	CNMP_BINDING_2	KCNH8 SLC9C1 SLC9C2 KCNH4	1.01e-03	32	263	4	PS00889
Domain	Ubiquitin_3	USP11 USP15	1.16e-03	4	263	2	PF14836
Domain	Ub_USP-typ	USP11 USP15	1.16e-03	4	263	2	IPR028135
Domain	Aldolase_II	ADD1 ADD3	1.16e-03	4	263	2	SM01007
Domain	Aldolase_II/adducin_N	ADD1 ADD3	1.16e-03	4	263	2	IPR001303
Domain	Cornichon	CNIH3 CNIH2	1.16e-03	4	263	2	PF03311
Domain	Cornichon	CNIH3 CNIH2	1.16e-03	4	263	2	SM01398
Domain	Glyco_transf_22	ALG12 ALG9	1.16e-03	4	263	2	PF03901
Domain	Aldolase_II	ADD1 ADD3	1.16e-03	4	263	2	PF00596
Domain	GPI_mannosylTrfase	ALG12 ALG9	1.16e-03	4	263	2	IPR005599
Domain	Tyr_kinase_non-rcpt_Jak/Tyk2	JAK2 JAK3	1.16e-03	4	263	2	IPR016251
Domain	-	ADD1 ADD3	1.16e-03	4	263	2	3.40.225.10
Domain	Cornichon	CNIH3 CNIH2	1.16e-03	4	263	2	IPR003377
Domain	cNMP	KCNH8 SLC9C1 SLC9C2 KCNH4	1.28e-03	34	263	4	SM00100
Domain	PAS	KCNH8 NPAS3 PER3 KCNH4	1.28e-03	34	263	4	PS50112
Domain	PAS	KCNH8 NPAS3 PER3 KCNH4	1.28e-03	34	263	4	IPR000014
Domain	cNMP_binding	KCNH8 SLC9C1 SLC9C2 KCNH4	1.28e-03	34	263	4	PF00027
Domain	cNMP-bd_dom	KCNH8 SLC9C1 SLC9C2 KCNH4	1.43e-03	35	263	4	IPR000595
Domain	CNMP_BINDING_3	KCNH8 SLC9C1 SLC9C2 KCNH4	1.43e-03	35	263	4	PS50042
Domain	MAM	NRP2 PTPRK PTPRM	1.62e-03	17	263	3	SM00137
Domain	PHR	BTBD1 BTBD2	1.92e-03	5	263	2	IPR012983
Domain	L-lactate_DH_AS	LDHAL6B LDHC	1.92e-03	5	263	2	IPR018177
Domain	Short_hematopoietin_rcpt_2_CS	IL13RA2 IL5RA	1.92e-03	5	263	2	IPR003532
Domain	HEMATOPO_REC_S_F2	IL13RA2 IL5RA	1.92e-03	5	263	2	PS01356
Domain	L_LDH	LDHAL6B LDHC	1.92e-03	5	263	2	PS00064
Domain	PHR	BTBD1 BTBD2	1.92e-03	5	263	2	PF08005
Domain	L-lactate_DH	LDHAL6B LDHC	1.92e-03	5	263	2	IPR011304
Domain	MAM	NRP2 PTPRK PTPRM	1.93e-03	18	263	3	PF00629
Domain	MAM_dom	NRP2 PTPRK PTPRM	1.93e-03	18	263	3	IPR000998
Domain	MAM_2	NRP2 PTPRK PTPRM	1.93e-03	18	263	3	PS50060
Domain	cNMP-bd-like	KCNH8 SLC9C1 SLC9C2 KCNH4	1.95e-03	38	263	4	IPR018490
Pathway	WP_GPCRS_PEPTIDE	TRHR AVPR1A GALR2 NTSR1 EDNRB OPRD1 OPRK1 OPRM1	7.60e-06	70	205	8	MM15959
Pathway	WP_PEPTIDE_GPCRS	TRHR AVPR1A GALR2 NTSR1 EDNRB OPRD1 OPRK1 OPRM1	1.28e-05	75	205	8	M39696
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	KCNH8 AIMP1 TMEM63B ZNF236 UBN2 DNAH14 JAK2 STK10 SENP1 INTS2 TBC1D1 FBXO42 TRMT13 DOCK6 USP15 KDM6A ALG12 SHROOM3 KAT6A SMURF1 CHCHD6 FAM117B ECPAS LRRC8D CCND3 NADSYN1 ZNF33B LRRC1 PRKAG1 NUMB EIF2AK4 CNOT1	1.44e-07	1489	265	32	28611215
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	ADD1 ADD3 NRP2 EFR3A STK10 RFTN1 PTPRK PTPRM FMN1 DLG2 DOCK9 NECTIN3 DOCK7 NUMB XPR1	2.50e-07	377	265	15	38117590
Pubmed	Quantitative autoradiography of mu-,delta- and kappa1 opioid receptors in kappa-opioid receptor knockout mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	10082819
Pubmed	Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	18537939
Pubmed	Opioid receptors: from binding sites to visible molecules in vivo.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	18718480
Pubmed	Heterodimerization of mu and delta opioid receptors: A role in opiate synergy.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	11069979
Pubmed	Association between human opioid receptor genes polymorphisms and pressure pain sensitivity in females*.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	19032295
Pubmed	The delta agonists DPDPE and deltorphin II recruit predominantly mu receptors to produce thermal analgesia: a parallel study of mu, delta and combinatorial opioid receptor knockout mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	15090050
Pubmed	Cell-specific actions of HIV-Tat and morphine on opioid receptor expression in glia.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	18338799
Pubmed	Cloning, expression, and characterization of three new mouse cytochrome p450 enzymes and partial characterization of their fatty acid oxidation activities.	CYP2C19 CYP2C9 CYP2C18	4.37e-07	3	265	3	15102943
Pubmed	Searching for evidence of genetic mediation of opioid withdrawal by opioid receptor gene polymorphisms.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	26692286
Pubmed	Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	17374034
Pubmed	Autoradiography of opioid and ORL1 ligands in opioid receptor triple knockout mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	12431223
Pubmed	Modelling the PKPD of oxycodone in experimental pain - Impact of opioid receptor polymorphisms.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	26946441
Pubmed	Motivational effects of cannabinoids are mediated by mu-opioid and kappa-opioid receptors.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	11826143
Pubmed	Cloning and expression of complementary DNAs for multiple members of the human cytochrome PH50IIC subfamily.	CYP2C19 CYP2C9 CYP2C18	4.37e-07	3	265	3	8095407
Pubmed	Acute antinociceptive responses in single and combinatorial opioid receptor knockout mice: distinct mu, delta and kappa tones.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	12603260
Pubmed	No evidence for G-protein-coupled epsilon receptor in the brain of triple opioid receptor knockout mouse.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	15178356
Pubmed	Pharmacological characterization of the cloned kappa-, delta-, and mu-opioid receptors.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	8114680
Pubmed	Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	11032994
Pubmed	Systemic morphine treatment derails normal uterine receptivity, leading to embryo implantation failure in mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	25855262
Pubmed	Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	18213616
Pubmed	Long-term alterations in mu, delta and kappa opioidergic receptors following middle cerebral artery occlusion in mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	17676326
Pubmed	Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.	RAET1G ULBP2 RAET1L	4.37e-07	3	265	3	25212604
Pubmed	Immunosuppression by delta-opioid antagonist naltrindole: delta- and triple mu/delta/kappa-opioid receptor knockout mice reveal a nonopioid activity.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	11504820
Pubmed	The efficacy of Dynorphin fragments at the κ, μ and δ opioid receptor in transfected HEK cells and in an animal model of unilateral peripheral inflammation.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	28049031
Pubmed	Nociception increases during opioid infusion in opioid receptor triple knock-out mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	17544222
Pubmed	Endogenous opioid receptor genes and alcohol dependence among Taiwanese Han.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	14745298
Pubmed	Opioid receptor characterisation of neuronally stimulated isolated human vas deferens.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	22752269
Pubmed	Distinct mu, delta, and kappa opioid receptor mechanisms underlie low sociability and depressive-like behaviors during heroin abstinence.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	24874714
Pubmed	Controlling opioid receptor functional selectivity by targeting distinct subpockets of the orthosteric site.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	33555255
Pubmed	Enhanced humoral response in kappa-opioid receptor knockout mice.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	12507774
Pubmed	Neurofilament proteins and cAMP pathway in brains of mu-, delta- or kappa-opioid receptor gene knock-out mice: effects of chronic morphine administration.	OPRD1 OPRK1 OPRM1	4.37e-07	3	265	3	14975676
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	AIMP1 TTLL9 SLC38A1 AP1B1 GFPT2 WDR17 KDM6A PREX1 USP47 TRAPPC11 RBM11 TBX4 HECTD3 TBPL1 POLE USP6 INTS13 MRPS24 CNOT1	5.53e-07	638	265	19	31182584
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	USP11 USP25 BTBD1 DBT NDUFA10 UBR5 USP7 ALB USP15 TADA3 MOB4 USP47 USP49 ACAD9 BTBD2 PRPF8 USP6 CSE1L PA2G4 DOCK7 PRKAG1 EIF2AK4 MPHOSPH9 CNOT1	9.47e-07	1005	265	24	19615732
Pubmed	Systematic mapping of genetic interactions for de novo fatty acid synthesis identifies C12orf49 as a regulator of lipid metabolism.	CYP2C9 RPS3A OLA1 ZNF236 LENG8 INTS2 UBR5 KCTD5 FBXO42 OR4K1 SEC16A USP7 NIT1 DIAPH3 TADA3 ALG12 TLK2 ACAD9 SMURF1 PREX2 CCND3 NBAS TKT ALG9 PRKAG1 EIF2AK4 MAP2K7 CNOT1	1.31e-06	1327	265	28	32694731
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	LSG1 USP11 RPS3A DBT ADD1 ADD3 MTPN EFR3A TMX1 SENP1 SACS UBR5 DIAPH3 TADA3 SHROOM3 L3MBTL2 HECTD3 ACAD9 POLE CHCHD6 AIP PRPF8 NBAS PA2G4 UTP4 TLN1 MRPS24 LRRC1 NUMB XPR1	1.34e-06	1487	265	30	33957083
Pubmed	Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.	RAET1G ULBP2 RAET1L	1.74e-06	4	265	3	20166740
Pubmed	Interactions of opioid and chemokine receptors: oligomerization of mu, kappa, and delta with CCR5 on immune cells.	OPRD1 OPRK1 OPRM1	1.74e-06	4	265	3	12413885
Pubmed	Developmental expression of the mu, kappa, and delta opioid receptor mRNAs in mouse.	OPRD1 OPRK1 OPRM1	1.74e-06	4	265	3	9502813
Pubmed	Quantitative autoradiographic mapping of the ORL1, mu-, delta- and kappa-receptors in the brains of knockout mice lacking the ORL1 receptor gene.	OPRD1 OPRK1 OPRM1	1.74e-06	4	265	3	11430857
Pubmed	Association of cytochrome P450 2C19 genotype with the antiplatelet effect and clinical efficacy of clopidogrel therapy.	CYP2C19 CYP2C9 CYP2C18	1.74e-06	4	265	3	19706858
Pubmed	A Dual Noradrenergic Mechanism for the Relief of Neuropathic Allodynia by the Antidepressant Drugs Duloxetine and Amitriptyline.	OPRD1 OPRK1 OPRM1	1.74e-06	4	265	3	30249798
Pubmed	Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin.	RAET1G ULBP2 RAET1L	1.74e-06	4	265	3	12421908
Pubmed	NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.	RAET1G ULBP2 RAET1L	1.74e-06	4	265	3	12756263
Pubmed	Murine NKG2D ligands: "double, double toil and trouble".	RAET1G ULBP2 RAET1L	1.74e-06	4	265	3	19081632
Pubmed	Biochemistry and molecular biology of the human CYP2C subfamily.	CYP2C19 CYP2C9 CYP2C18	1.74e-06	4	265	3	7704034
Pubmed	Cloning and expression of complementary DNAs for multiple members of the human cytochrome P450IIC subfamily.	CYP2C19 CYP2C9 CYP2C18	1.74e-06	4	265	3	2009263
Pubmed	Multiple opioid receptor-like genes are identified in diverse vertebrate phyla.	OPRD1 OPRK1 OPRM1	1.74e-06	4	265	3	8941707
Pubmed	Genetic variation in the CYP2C monooxygenase enzyme subfamily shows no association with longevity in a German population.	CYP2C19 CYP2C9 CYP2C18	1.74e-06	4	265	3	21798861
Pubmed	Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.	RAET1G ULBP2 RAET1L	1.74e-06	4	265	3	8882725
Pubmed	Activation of delta-, kappa-, and mu-opioid receptors induces phosphorylation of tuberin in transfected HEK 293 cells and native cells.	OPRD1 OPRK1 OPRM1	1.74e-06	4	265	3	16053916
Pubmed	Genetic variants associated with warfarin dose in African-American individuals: a genome-wide association study.	CYP2C19 CYP2C9 CYP2C18	1.74e-06	4	265	3	23755828
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	USP11 USP25 BTBD1 NDUFA10 RYR3 ADD3 MTPN STAB1 TRIM66 PTPRK SACS USP7 DLG2 GFPT2 WDR17 KDM6A PREX1 DYNC1H1 USP47 RBM11 MSH3 AIP BTBD2 PRPF8 EEF2 DROSHA CEP70	2.22e-06	1285	265	27	35914814
Pubmed	Systematic Analysis of Human Protein Phosphatase Interactions and Dynamics.	USP11 DBT INTS2 UBR5 SEC16A DYNC1H1 MOB4 ACAD9 MINPP1 PRPF8 PPP1R3C CSE1L PA2G4 INTS13 TKT LRRC1 MAPK1	2.33e-06	573	265	17	28330616
Pubmed	Deubiquitinating enzymes: a new class of biological regulators.	USP11 USP7 USP15 USP6	4.21e-06	15	265	4	9827704
Pubmed	MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.	RAET1G ULBP2 RAET1L	4.32e-06	5	265	3	24572784
Pubmed	Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain.	RAET1G ULBP2 RAET1L	4.32e-06	5	265	3	8982867
Pubmed	Identification and characterization of novel candidate compounds targeting 6- and 7-transmembrane μ-opioid receptor isoforms.	OPRD1 OPRK1 OPRM1	4.32e-06	5	265	3	33782947
Pubmed	Balancing BMP signaling through integrated inputs into the Smad1 linker.	SMURF1 MAPK1 SMAD1	4.32e-06	5	265	3	17289590
Pubmed	Variations in opioid receptor genes in neonatal abstinence syndrome.	OPRD1 OPRK1 OPRM1	4.32e-06	5	265	3	26233486
Pubmed	A deep proteomics perspective on CRM1-mediated nuclear export and nucleocytoplasmic partitioning.	RPS3A ADD1 ADD3 STK10 AP1B1 UBR5 KCTD5 EIF2B2 SEC16A DIAPH3 DOCK6 WWC1 USP47 L3MBTL2 CDC37L1 DROSHA UTP4 DOCK7 NUMB MPHOSPH9 MAP2K7 CNOT1 SMAD1	5.53e-06	1038	265	23	26673895
Pubmed	Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.	SPAG1 GCNT4 CHRNA1 SLC38A1 JAK2 DLG2 SARDH KDM6A FNDC3B LAMA2 GXYLT1 MSH3 MINPP1 KBTBD4 LRRC1 PRKAG1 NUMB HYDIN	6.41e-06	686	265	18	29987050
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	USP11 TMX1 AP1B1 PTPRK PTPRM UBR5 SEC16A DIAPH3 WWC1 USP47 ACAD9 POLE ATL3 AIP ECPAS PRPF8 CSE1L PREP TKT LRRC1 MAPK1 XPR1	6.60e-06	974	265	22	28675297
Pubmed	A growth factor attenuates HIV-1 Tat and morphine induced damage to human neurons: implication in HIV/AIDS-drug abuse cases.	OPRD1 OPRK1 OPRM1 MAPK1	7.25e-06	17	265	4	21483469
Pubmed	A multi-factor trafficking site on the spliceosome remodeling enzyme BRR2 recruits C9ORF78 to regulate alternative splicing.	USP11 NDUFA10 ADD1 LENG8 AP1B1 DYNC1H1 ACAD9 MSH3 ECPAS PRPF8 ORC5 CSE1L INTS13 UTP4 LRRC1 CNOT1	7.42e-06	560	265	16	35241646
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	STK17B RIPK2 MTPN JAK2 TMX1 PHKA2 STK10 AP1B1 INTS2 USP7 CCNI TLK2 ARHGAP23 AIP CCND3 TLN1 PRKAG1 NUMB EIF2AK4 MAPK1 PDE7B	7.80e-06	910	265	21	36736316
Pubmed	E-cadherin interactome complexity and robustness resolved by quantitative proteomics.	SPAG1 OLA1 ADD1 ADD3 EFR3A SLC38A1 FMN1 DIAPH3 USP15 SHROOM3 ARHGAP23 DOCK9 EEF2 NUDT5 TLN1 NUMB	8.28e-06	565	265	16	25468996
Pubmed	Opioid receptor gene expression in dopamine transporter knock-out mice in adult and during development.	OPRD1 OPRK1 OPRM1	8.60e-06	6	265	3	12044478
Pubmed	Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.	RAET1G ULBP2 RAET1L	8.60e-06	6	265	3	11825567
Pubmed	Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.	RAET1G ULBP2 RAET1L	8.60e-06	6	265	3	10894171
Pubmed	Ligands for murine NKG2D display heterogeneous binding behavior.	RAET1G ULBP2 RAET1L	8.60e-06	6	265	3	11857333
Pubmed	A genome-wide association study of acenocoumarol maintenance dosage.	CYP2C19 CYP2C9 CYP2C18	8.60e-06	6	265	3	19578179
Pubmed	Genetic susceptibility to heroin addiction: a candidate gene association study.	OPRD1 OPRK1 OPRM1	8.60e-06	6	265	3	18518925
Pubmed	Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.	RAET1G ULBP2 RAET1L	8.60e-06	6	265	3	20219610
Pubmed	The NKG2D ligands RAE-1δ and RAE-1ε differ with respect to their receptor affinity, expression profiles and transcriptional regulation.	RAET1G ULBP2 RAET1L	8.60e-06	6	265	3	20976056
Pubmed	Expression of opioid receptors and ligands in pregnant mouse uterus and placenta.	OPRD1 OPRK1 OPRM1	8.60e-06	6	265	3	9746745
Pubmed	Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.	RAET1G ULBP2 RAET1L	8.60e-06	6	265	3	19688209
Pubmed	Photocaged Cell-Permeable Ubiquitin Probe for Temporal Profiling of Deubiquitinating Enzymes.	AIMP1 USP11 USP7 USP15 USP47 ATL3	9.57e-06	64	265	6	33141564
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	AP1B1 UBR5 TBC1D1 SEC16A DOCK6 MOB4 WWC1 SHROOM3 AIP ECPAS DOCK7 MPHOSPH9 CNOT1 XPR1	9.79e-06	446	265	14	24255178
Pubmed	Dissociation of heterotrimeric g proteins in cells.	PTAFR GALR2 ADORA1 CCL19 NTSR1 EDNRB OPRD1 OPRK1 OPRM1	1.04e-05	179	265	9	18577758
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	SPAG1 AIMP1 OLA1 NDUFA10 TMX1 SLC9C1 EML5 KCTD5 TBC1D1 EIF2B2 SEC16A USP15 DYNC1H1 MOB4 TLK2 ACAD9 CHCHD6 FAM117B PRPF8 CSE1L NUDT5 PA2G4 DOCK7 NUMB CNOT1 PCDH9	1.09e-05	1321	265	26	27173435
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	USP11 NPAS3 HIRA HOXA10 PHKA2 UBR5 FBXO42 ALB DYNC1H1 USP47 L3MBTL2 POLE PARG HMGXB4 MSH3 ECPAS PRPF8 TTLL7 ORC5 PA2G4	1.10e-05	857	265	20	25609649
Pubmed	Direct interaction between hnRNP-M and CDC5L/PLRG1 proteins affects alternative splice site choice.	OLA1 STAB1 AP1B1 DIAPH3 DYNC1H1 SHROOM3 POLE PRPF8 ORC5 CSE1L INTS13 TLN1 LRRC1 PRKAG1 MAP2K7 CNOT1	1.19e-05	582	265	16	20467437
Pubmed	Defining the membrane proteome of NK cells.	ABHD17A AIMP1 LSG1 OLA1 INTS2 UBR5 ABCD1 ALG12 DYNC1H1 DOCK9 ATL3 MSH3 ECPAS PRPF8 LRRC8D NBAS EEF2 CSE1L PA2G4 PREP ALG9 PRKAG1 MPHOSPH9 CNOT1	1.20e-05	1168	265	24	19946888
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	USP11 RPS3A AP1B1 UBR5 SEC16A USP7 DYNC1H1 USP47 POLE ECPAS PRPF8 CSE1L PREP UTP4 TLN1 DOCK7 CNOT1	1.29e-05	653	265	17	22586326
Pubmed	Mapping the MOB proteins' proximity network reveals a unique interaction between human MOB3C and the RNase P complex.	AIMP1 UBR5 SEC16A USP7 DOCK6 USP15 DYNC1H1 MOB4 USP47 ATL3 CSE1L TLN1 DOCK7	1.38e-05	399	265	13	37536630
Pubmed	The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.	RAET1G ULBP2 RAET1L	1.50e-05	7	265	3	16831899
Pubmed	Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.	RAET1G ULBP2 RAET1L	1.50e-05	7	265	3	20870941
Pubmed	Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma.	RAET1G ULBP2 RAET1L	1.50e-05	7	265	3	26151313
Pubmed	NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis.	RAET1G ULBP2 RAET1L	1.50e-05	7	265	3	30787931
Pubmed	Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.	RAET1G ULBP2 RAET1L	1.50e-05	7	265	3	12370332
Pubmed	[Association of xenobiotic-metabolizing gene polymorphisms with childhood atopic diseases in Russian patients from the Republic of Bashkortostan].	CYP2C19 CYP2C9 GSTM1	1.50e-05	7	265	3	20088379
Pubmed	NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.	RAET1G ULBP2 RAET1L	1.50e-05	7	265	3	25583577
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ACTR5 LSG1 USP11 DBT HOXA9 HOXA10 TRIM66 SENP1 EML5 UBR5 SEC16A USP7 TEKT1 TADA3 WWC1 ARHGAP23 HECTD3 HMGXB4 KAT6A CCNB3 DROSHA INTS13 MAP2K7	1.76e-05	1116	265	23	31753913
Pubmed	Discovery and Characterization of ZUFSP/ZUP1, a Distinct Deubiquitinase Class Important for Genome Stability.	USP11 USP25 UBR5 USP7 USP15 USP47 POLE USP6	1.83e-05	147	265	8	29576527
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	AIMP1 USP11 RPS3A USP25 OLA1 MTPN AP1B1 EIF2B2 SEC16A USP7 USP15 KYNU DYNC1H1 MOB4 USP47 HECTD3 LDHAL6B AIP ECPAS CDC37L1 EEF2 CSE1L NUDT5 PA2G4 INTS13 TLN1 CNOT1	2.08e-05	1455	265	27	22863883
Pubmed	Interactome of the Autoimmune Risk Protein ANKRD55.	RPS3A UBR5 USP7 DYNC1H1 PRPF8 EEF2 CSE1L TLN1 CNOT1	2.23e-05	197	265	9	31620119
Pubmed	A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity.	RAET1G ULBP2 RAET1L	2.38e-05	8	265	3	12645935
Pubmed	Biological definition of multiple chemical sensitivity from redox state and cytokine profiling and not from polymorphisms of xenobiotic-metabolizing enzymes.	CYP2C19 CYP2C9 GSTM1	2.38e-05	8	265	3	20430047
Interaction	DUSP2 interactions	USP11 UBR5 SEC16A USP7 ACAD9 POLE AIP ECPAS PRPF8 PRKAG1 MAPK1	6.46e-09	81	257	11	int:DUSP2
GeneFamily	Ubiquitin specific peptidases	USP11 USP25 USP7 USP15 USP47 USP49 USP6	1.18e-06	56	177	7	366
GeneFamily	Opioid receptors	OPRD1 OPRK1 OPRM1	3.66e-06	4	177	3	245
GeneFamily	Armadillo repeat containing\|Protein phosphatase 1 regulatory subunits	SACS DLG2 WWC1 CHCHD6 PREX2 PPP1R3C ORC5 HYDIN	4.18e-04	181	177	8	694
GeneFamily	CD molecules\|I-set domain containing\|Immunoglobulin like domain containing\|Interleukin receptors\|TIR domain containing	IL13RA2 IL18RAP IL17RB IL5RA	7.43e-04	42	177	4	602
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	SNX13 HIRA EFR3A STK10 RFTN1 PTPRK PTPRM SACS UBR5 USP7 USP15 MOB4 WWC1 TLK2 DOCK9 PARG HMGXB4 KAT6A MSH3 NECTIN3 ORC5 USP6 NBAS CSE1L NUMB MPHOSPH9	5.16e-07	856	261	26	M4500
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	ABHD17A WWC3 RPS3A STK17B USP25 FBXW2 BTBD1 PITPNC1 IL18RAP ADD1 EFR3A SLC38A1 JAK3 STK10 RFTN1 TRANK1 SACS UBR5 TBC1D1 GPR171 USP15 CCNI PREX1 DYNC1H1 USP47 DOCK9 KAT6A AIP PRPF8 CCND3 TLN1 OXNAD1 MAPK1 FBXL20 CNOT1	2.26e-06	1492	261	35	M40023
Coexpression	GSE16450_CTRL_VS_IFNA_6H_STIM_IMMATURE_NEURON_CELL_LINE_UP	AVPR1A PITPNC1 ZNF236 STAB1 JAK2 SACS ATF7IP2 UMOD GPR171 ZNF628 TTLL7	5.72e-06	200	261	11	M7417
Coexpression	DESCARTES_ORGANOGENESIS_EPENDYMAL_CELL	TRHR TTLL9 AK9 TEKT1 DLEC1 CFAP47 SHROOM3 EFCAB6 ODAD2 AGBL4 AGBL2 HYDIN	2.87e-05	282	261	12	MM3642
Coexpression	GSE37416_0H_VS_12H_F_TULARENSIS_LVS_NEUTROPHIL_UP	STK17B ADD1 ADD3 JAK2 PHKA2 FAM117B USP6 NUDT5 MAPK1 LY75	3.04e-05	197	261	10	M5347
Coexpression	GSE43955_TH0_VS_TGFB_IL6_TH17_ACT_CD4_TCELL_1H_UP	AIMP1 COQ3 JAK2 TAT CHCHD6 AIP EDNRB EEF2 UTP4 IL5RA	3.46e-05	200	261	10	M9635
CoexpressionAtlas	DevelopingKidney_e15.5_stage III -IV renal corpusc_emap-27945_k-means-cluster#5_top-relative-expression-ranked_1000	FBXW2 CHST9 EFR3A PER3 USP7 UMOD TRMT13 WWC1 FNDC3B FASTKD1 HMGXB4 MSH3 CDC37L1	3.59e-06	226	254	13	gudmap_developingKidney_e15.5_stage III -IV renal corpusc_1000_k5
CoexpressionAtlas	Stromal Cells, LEC.SLN, gp38+ CD31+, Lymph Node, avg-4	IL13RA2 TNFRSF11A NRP2 STAB1 BMX PTPRK PTPRM SERPING1 DOCK6 PLXNA2 ARHGAP23 TCN2 DOCK9 EDNRB GXYLT2 PDE7B SMAD1	3.25e-05	450	254	17	GSM777063_500
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SPAG1 TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 ZNF19 IL5RA HYDIN	8.06e-11	181	267	13	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Epithelial-ciliated_cell\|World / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 AGBL2 IL5RA HYDIN	1.68e-09	188	267	12	61a459f3fe57e5728efc72637ff2edc2d343492b
ToppCell	Adult-Epithelial-ciliated_cell\|Adult / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 AGBL2 IL5RA HYDIN	1.79e-09	189	267	12	b679920f0993e917dd86da082113bfbd85ea1ca5
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TRHR TMEM63B DNAH14 SLC9C1 PLXNA2 WWC1 SHROOM3 DOCK9 NECTIN3 TKT CEP70	1.35e-08	181	267	11	576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 AGBL2 HYDIN	1.43e-08	182	267	11	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	COVID-19-Epithelial_cells-Airway_ciliated\|COVID-19 / group, cell type (main and fine annotations)	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 AGBL2 HYDIN	1.69e-08	185	267	11	18a40f0a338aa398d81384b5159fb80ce8a2020c
ToppCell	Adult-Epithelial-ciliated_cell-D231\|Adult / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 IL5RA HYDIN	2.00e-08	188	267	11	34b11f72ca73153d02edcd09b38983ad1a504659
ToppCell	COVID-19-lung-Ciliated\|lung / Disease (COVID-19 only), tissue and cell type	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 IL5RA HYDIN	2.11e-08	189	267	11	27329c4661aebabd19fac7fe5dca263fe99d76f3
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 IL5RA HYDIN	2.11e-08	189	267	11	68a3cf7763d6f9b95d6d6524eff7a16042703f1d
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL4 ZNF19 IL5RA	1.30e-07	178	267	10	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL4 AGBL2 HYDIN	1.60e-07	182	267	10	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Adult-Epithelial-ciliated_cell-D175\|Adult / Lineage, Cell type, age group and donor	TTLL9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL4 AGBL2 IL5RA HYDIN	1.86e-07	185	267	10	30f4980dee6cd5959655f8d74049f3bfb5312611
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA2 BMX PTPRM SEC16A PREX1 ARHGAP23 TCN2 DOCK9 SMURF1 MPHOSPH9	2.06e-07	187	267	10	3699d5e71d779da922920aa3160895db187bf81b
ToppCell	E18.5-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP1-CAP1_mature\|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PHKA2 BMX PTPRM SEC16A PREX1 ARHGAP23 TCN2 DOCK9 SMURF1 MPHOSPH9	2.06e-07	187	267	10	033ba52c0c2f9978784947098fa697368ae44834
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL4 IL5RA HYDIN	2.16e-07	188	267	10	2b6dfc88be9ded7b88da9fe78a9cd9f9b3af8af3
ToppCell	nucseq-Epithelial-Epithelial_Airway\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 HYDIN	2.50e-07	191	267	10	1c528f72c9ef3ef3a850b05e4a9715190832270c
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal-Ciliated\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 HYDIN	2.50e-07	191	267	10	e417bf491f8b8d7838a61f7f4f6b1740ba97aa3f
ToppCell	nucseq-Epithelial-Epithelial_Airway-Ciliated/Deuterosomal\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 SLC9C2 AGBL4 HYDIN	2.50e-07	191	267	10	9d31c8424d35bdc0c27188b68bfd0f731af3600b
ToppCell	facs-Aorta-Heart-3m\|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADD1 MTPN STAB1 ALB CCNI KAT6A FAM117B EDNRB CD38 HYDIN	2.63e-07	192	267	10	1ccc47792edf9ee23501c8e2165d11271636b66a
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B IL18RAP SLC38A1 JAK3 STK10 RFTN1 GPR171 PREX1 OPRM1 OXNAD1	3.83e-07	200	267	10	5f41906cf1585e09b150a84364d47c3e466dc5b7
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8_TRM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B PITPNC1 IL18RAP SLC38A1 STK10 GPR171 PREX1 OPRM1 CCND3 OXNAD1	3.83e-07	200	267	10	be9a43acc2f926b9433ab3f018b911b03896a924
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL2 IL5RA HYDIN	3.83e-07	200	267	10	926a7ea94b5908aebf103893ea83ce9d25285b65
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL2 IL5RA HYDIN	3.83e-07	200	267	10	06ce6e03498ba38ef6a06eaf2731e3b2eeda59eb
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B PITPNC1 IL18RAP SLC38A1 JAK3 STK10 GPR171 PREX1 OPRM1 OXNAD1	3.83e-07	200	267	10	dfdfad881c114e1bc9a64b411e1b00fb37cc859b
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_prolif\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	TNFRSF11A PITPNC1 NRP2 STAB1 HOXD10 PLXNA2 ANO4 MPHOSPH9 SMAD1	7.13e-07	165	267	9	50a8513d8d2630861499393a7f102b35366bad37
ToppCell	Children_(3_yrs)-Epithelial-ciliated_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 IL5RA HYDIN	1.77e-06	184	267	9	5daff849625f2f41d56615569c0ed59cd733b34c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH14 SLC9C1 DLG2 WWC1 DOCK9 NECTIN3 TKT CEP70 PCDH9	1.93e-06	186	267	9	acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 AGBL4 IL5RA	2.02e-06	187	267	9	9e10ed56090d82589bc457788282f664b70ace4b
ToppCell	human_hepatoblastoma-NK.T_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	STK17B IL18RAP SLC38A1 JAK3 STK10 RFTN1 GPR171 PREX1 CCND3	2.11e-06	188	267	9	71b7599e7e1d63cc0c8518c0501533755951d58f
ToppCell	COPD-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	SPAG1 PITPNC1 IL18RAP SLC38A1 DIAPH3 WWC1 AGBL4 UTP4 HYDIN	2.11e-06	188	267	9	186fe1ea328c942910190a4240262c0d8642ea3b
ToppCell	COVID-19-lung-Ciliated\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 SLC9C2 IL5RA HYDIN	2.20e-06	189	267	9	a2da5debd10f27b1280b40141ef0bfef007cc72c
ToppCell	COVID-19-lung-Lymphatic_EC\|lung / Disease (COVID-19 only), tissue and cell type	NPAS3 TNFRSF11A NRP2 SLC38A1 EDNRB LRRC1 GNAT3 PDE7B SMAD1	2.20e-06	189	267	9	c8db9aaf54ea3cc96c4a2f777c3389e0f31f67f3
ToppCell	COVID-19-T_cells-CD4+_T_cells\|COVID-19 / group, cell type (main and fine annotations)	STK17B PITPNC1 SLC38A1 JAK3 GPR171 DOCK9 OPRM1 CCND3 OXNAD1	2.40e-06	191	267	9	0646cca78e24aeb6baa9934d3c439b797c567997
ToppCell	LPS-antiTNF-Stromal_mesenchymal-Fibroblasts\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PER3 DIAPH3 HECTD3 ODAD2 PPP1R3C GXYLT2 MASP2 MYBPC1	2.47e-06	143	267	8	57ee1830d96d73d92b5f83b028592a5d952c6013
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A NRP2 STAB1 HOXD10 PTPRM PLXNA2 DOCK9 PREX2 EDNRB	2.51e-06	192	267	9	945153c41dde6e90d103206955e1707b54eb0665
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A NRP2 STAB1 HOXD10 PTPRM PLXNA2 DOCK9 PREX2 EDNRB	2.51e-06	192	267	9	6ab50579c63f31ca2cd41063a99b129f11c07510
ToppCell	droplet-Mammary_Gland-nan-18m-Endothelial-endothelial_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNFRSF11A NRP2 STAB1 HOXD10 PTPRM PLXNA2 DOCK9 PREX2 EDNRB	2.85e-06	195	267	9	4db30b3bc65c25626f828cd4f867f20c71809898
ToppCell	nucseq-Epithelial\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH14 SLC9C1 PTPRK PTPRM ATF7IP2 DLG2 WWC1 SHROOM3 CEP70	2.85e-06	195	267	9	9406866f99555198a9be311fbd65751b70f35446
ToppCell	Control_saline-Epithelial_airway-airway_epithelial-Ciliated\|Control_saline / Treatment groups by lineage, cell group, cell type	SPAG1 TTLL9 AK9 TEKT1 DLEC1 ODAD2 AGBL4 IL5RA HYDIN	2.85e-06	195	267	9	60067b5359174f0d1a8b5748bfc0690762e9e740
ToppCell	facs-Lung-nan-3m-Endothelial\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	STAB1 PTPRK PTPRM PLXNA2 TCN2 DOCK9 EDNRB CD38 NUMB	2.85e-06	195	267	9	7f9b7f15006610ad591063d90e90367bd6083c7f
ToppCell	distal-Hematologic-Plasma-1\|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	GALR2 EML5 UNC79 MOB4 MEI1 TTLL7 EIF2AK4 RNF207 IL5RA	2.97e-06	196	267	9	8201aded3c7109fae5e6ca12bac2076acc7bf070
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	SLC9C1 PTPRK TEKT1 WWC1 CFAP47 SHROOM3 ODAD2 AGBL4 HYDIN	2.97e-06	196	267	9	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTLL9 AK9 DLEC1 ANO4 CFAP47 EFCAB6 SLC9C2 AGBL4 HYDIN	3.09e-06	197	267	9	74a2c6cb8fcfe53dd9a2b36492a16c58f38e51c9
ToppCell	COVID-19-kidney-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	NPAS3 TNFRSF11A GCNT4 NRP2 BMX LRRC1 PDE7B SMAD1	3.19e-06	148	267	8	f777aa1674e898e2594b2b7c029d3d05dda04df9
ToppCell	droplet-Lung-18m-Hematologic-lymphocytic-CD8-positive,_alpha-beta_T_cell-CD8-positive,_alpha-beta_T_cell_l21\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	ACTR5 CCL19 ZNF628 MSH3 PRPF8 MICU3 PNPLA3 MPHOSPH9	3.35e-06	149	267	8	65778f19599b4955c0a16f0121237656449431fb
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD8-CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B PITPNC1 IL18RAP SLC38A1 STK10 GPR171 PREX1 OPRM1 OXNAD1	3.36e-06	199	267	9	0d6463e368fd611a17327322413fad145f3c7f32
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4_naive/CM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B SLC38A1 JAK3 STK10 RFTN1 GPR171 PREX1 CCND3 OXNAD1	3.36e-06	199	267	9	6150b272313d3fbf5ddcb3a8d51862d368220fe2
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B PITPNC1 IL18RAP JAK3 STK10 GPR171 PREX1 OPRM1 OXNAD1	3.36e-06	199	267	9	fbdde57dd88656621801e65ee2818251588f3874
ToppCell	Tracheal-NucSeq-Immune_Lymphocytic-T-T_CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B IL18RAP JAK3 STK10 RFTN1 GPR171 PREX1 OPRM1 OXNAD1	3.50e-06	200	267	9	d8459e45a8396a9ee063666a1928c649162c5727
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated-Ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TTLL9 TEKT1 DLEC1 CFAP47 LRRIQ3 ODAD2 SLC9C2 AGBL2 IL5RA	3.50e-06	200	267	9	af6a551f83808c1c839df7ba7b1702ca28ea6e1b
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_ciliated\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	TTLL9 TEKT1 DLEC1 CFAP47 LRRIQ3 ODAD2 SLC9C2 AGBL2 IL5RA	3.50e-06	200	267	9	73ac1cf40ddd764be1100cbfaaa29563665457d8
ToppCell	Bronchial-NucSeq-Immune_Lymphocytic-T-T_CD8\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B PITPNC1 IL18RAP SLC38A1 STK10 GPR171 PREX1 OPRM1 OXNAD1	3.50e-06	200	267	9	02c4169a23e5aaa0d4bfc78b51ba19ce8157dc3e
ToppCell	LPS_IL1RA_TNF-Epithelial_airway-airway_epithelial-Ciliated\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	AK9 TEKT1 DLEC1 EFCAB6 ODAD2 SLC9C2 AGBL4 IL5RA HYDIN	3.50e-06	200	267	9	96701a4d57753f5ec0dd5c7550054bbcc946bc5f
ToppCell	Parenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	STK17B PITPNC1 IL18RAP JAK3 STK10 GPR171 PREX1 OPRM1 OXNAD1	3.50e-06	200	267	9	f7a9d8b99de19e9842422bada348d940e0863645
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 AGBL4 HYDIN	3.70e-06	151	267	8	8216462e723fec2797387929dde095370947e10a
ToppCell	Children_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KCNH8 NPAS3 B3GALT5 TMEM145 UNC79 OPRD1 AGBL4 SPHKAP	6.81e-06	164	267	8	be49af6335f2505065cde2cb9800e4a5516811b1
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_SEMA6D\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNAH14 PTPRK FMN1 FNDC3B LAMA2 OPRM1 PREP PDE7B	8.48e-06	169	267	8	319cba07263bf41fcbcbfecd117f91b729394241
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	TTLL9 AK9 WDR17 CFAP47 EFCAB6 AGBL4 ZNF19 HYDIN	8.48e-06	169	267	8	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	COVID-19-kidney-PCT-S3-2\|kidney / Disease (COVID-19 only), tissue and cell type	CYP2C9 CYP2C18 ALB SARDH TAT ACOT12 GREM2 PNPLA3	1.05e-05	174	267	8	5aa2fb631505600f37d2b87b02def7be139dc262
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2-Exc_L3-4_RORB_PRSS12\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	DNAH14 RYR3 PTPRK FMN1 SHROOM3 OPRM1 PREP SPHKAP	1.05e-05	174	267	8	ae363ce736fc8af439f3ad594d7bc2e344db80d4
ToppCell	10x_3'_v2v3-Non-neoplastic-Lymphoid-CD4/CD8-CD8_cytotoxic-D\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TRANK1 GPR171 DOCK9 FASTKD1 MEI1 CCND3 GREM2 OXNAD1	1.09e-05	175	267	8	a3f8c54c77bce9b035a4835945ab341909be4946
ToppCell	COVID-19-kidney-PCT-S3-2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	CYP2C9 CYP2C18 ALB SARDH TAT ACOT12 GREM2 PNPLA3	1.14e-05	176	267	8	b6497324e3e52f514ce556a3fa0c3011c45dcc7b
ToppCell	368C-Lymphocytic-NK_cells-NK_cell_E\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	ENPP1 HOXA9 HOXA10 ABCD1 CHCHD6 LRRC1 RNF207 PCDH9	1.19e-05	177	267	8	946803293a7955116c80f403e99e4093e798ca3f
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Hematopoietic-T_cells-LTi-like_NCR-_ILC3\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	STK17B ENPP1 IL18RAP GPR171 OPRK1 CACNA2D4 CD38 OXNAD1	1.34e-05	180	267	8	3f0a692ad2823951e0ec23d0452f436c5f5c09c0
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 ODAD2 AGBL4 IL5RA	1.64e-05	185	267	8	3e39a3cb534dfe2301930f3e2f7e8cefb522c158
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NPAS3 TNFRSF11A NRP2 HOXD10 DOCK9 GNAT3 PDE7B SMAD1	1.64e-05	185	267	8	f9f48251bc33eb6bf2cff580d1a3207d21450aa0
ToppCell	Ciliated_cells-B-IPF_01\|World / lung cells shred on cell class, cell subclass, sample id	TTLL9 CHST9 TEKT1 DLEC1 CFAP47 EFCAB6 ODAD2 HYDIN	1.70e-05	186	267	8	f72267d533fd0c5280d9741ceee3dd116300a7e4
ToppCell	systemic_lupus_erythematosus-flare-Lymphocytic_NK-T_mait-male\|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex	HIRA USP7 USP49 L3MBTL2 FASTKD1 GREM2 NARF ORC5	1.70e-05	186	267	8	927723ad579bbd9947ff525bd501e222d3fa9289
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SLC9C1 ATF7IP2 PLXNA2 WWC1 SHROOM3 SMURF1 NECTIN3 TKT	1.84e-05	188	267	8	43a3a59f92ad93509d4166bd025aed0b1b39a008
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	NPAS3 TNFRSF11A NRP2 HOXD10 DOCK6 GNAT3 PDE7B SMAD1	1.84e-05	188	267	8	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	RA-10._Endothelium_II\|RA / Chamber and Cluster_Paper	PITPNC1 BMX PTPRM DOCK6 PLXNA2 DOCK9 NUMB PDE7B	1.91e-05	189	267	8	c81787a8c662db5d7814c583dd64562857629e81
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CHST9 ASB18 PTPRM DLG2 LAMA2 SPHKAP RNF207 XPR1	1.91e-05	189	267	8	5e80c47f63980904c4c1ff02c201b67b456a0974
ToppCell	LV-06._Ventricular_Cardiomyocyte_II\|World / Chamber and Cluster_Paper	CHST9 ASB18 PTPRM DLG2 LAMA2 SPHKAP RNF207 XPR1	1.98e-05	190	267	8	de5ef606a002f85c2e0e3a36c1f259d0b85a76ff
ToppCell	IPF-Lymphoid-T\|IPF / Disease state, Lineage and Cell class	STK17B PITPNC1 SLC38A1 JAK3 GPR171 OPRM1 CCND3 OXNAD1	1.98e-05	190	267	8	d57df208aaf7a5554899bb9107c80b443fd0cf93
ToppCell	Control-T_cells-CD4+_T_cells\|Control / group, cell type (main and fine annotations)	PITPNC1 SLC38A1 STK10 GPR171 PREX1 OPRM1 CCND3 OXNAD1	1.98e-05	190	267	8	0733be5e54fe15d6d6ea51c154a95258e83f1b92
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_C_(IT_L4_RORB)\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	KCNH8 SPOCK1 STAC PTPRK CCNI NECTIN3 SPHKAP PDE7B	1.98e-05	190	267	8	1bbbf0ce222e51f9fd2daca0c18d3965fd4efd31
ToppCell	COVID-19-T_cells\|COVID-19 / group, cell type (main and fine annotations)	STK17B PITPNC1 SLC38A1 JAK3 STK10 GPR171 OPRM1 CCND3	2.06e-05	191	267	8	7f64add931b64b8d35836fa6bee9ebab593844d3
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	TMEM63B DNAH14 PTPRK PLXNA2 WWC1 SHROOM3 CCND3 CEP70	2.06e-05	191	267	8	ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCell	Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)\|World / Lineage, Cell type, age group and donor	TMEM63B DNAH14 SLC9C1 PTPRK PLXNA2 WWC1 SHROOM3 CEP70	2.06e-05	191	267	8	d3733c8c4bda70c4390e5601fdda6188a64be944
ToppCell	COVID-19-lung-Lymphatic_EC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	TNFRSF11A NRP2 SLC38A1 EDNRB LRRC1 GNAT3 PDE7B SMAD1	2.14e-05	192	267	8	cbe57cda44232b183821ac633b60a2668265e616
ToppCell	PCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	KCNH8 CHST9 SLC38A1 EML5 IL17RB WWC1 ARHGEF19 AGBL4	2.14e-05	192	267	8	d3634574b2e8d2ded6446969361b70761b331aea
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-endothelial_cell\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNC1 NRP2 STAB1 PTPRM PLXNA2 DOCK9 PREX2 EDNRB	2.14e-05	192	267	8	0986b7900021efe2a4df84a935e7c9a0af1b0e57
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNC1 STAB1 PTPRK PTPRM TCN2 DOCK9 CD38 NUMB	2.14e-05	192	267	8	4bab9754cfd8b9c2d7cc1490e8a29f58c3c26f6c
ToppCell	IPF-Lymphoid-T\|World / Disease state, Lineage and Cell class	STK17B PITPNC1 SLC38A1 JAK3 GPR171 OPRM1 CCND3 OXNAD1	2.14e-05	192	267	8	b25ba1f3bc842c22602b2aeed3b1b5082863e4fa
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNC1 NRP2 STAB1 PTPRM PLXNA2 DOCK9 PREX2 EDNRB	2.14e-05	192	267	8	b28d294e42b303d1db6060231d84d7b9e4d9fccf
ToppCell	facs-Diaphragm-Limb_Muscle-3m-Endothelial-nan\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PITPNC1 NRP2 STAB1 PTPRM PLXNA2 DOCK9 PREX2 EDNRB	2.14e-05	192	267	8	8f20d3511dcb44445592b17d005a53da0052ae56
ToppCell	10x5'-lymph-node_spleen-Lymphocytic_Invariant-Inducer-like-ILC3\|lymph-node_spleen / Manually curated celltypes from each tissue	SPAG1 ENPP1 B3GALT5 CHST9 TNFRSF11A STAC HOXA9 PCDH9	2.14e-05	192	267	8	e16035b3328f9b1b2e28d234c62ba88387540550
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DNAH14 PTPRK FMN1 DLG2 WWC1 DOCK9 CCND3 CEP70	2.14e-05	192	267	8	fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCell	RV-09._Endothelium_I\|World / Chamber and Cluster_Paper	PITPNC1 ADD1 RFTN1 SLC9C1 PTPRM PLXNA2 DOCK9 PREX2	2.22e-05	193	267	8	e3fa47e2c7cd8a5b69186711c57751f2296de8ae
ToppCell	COVID-19-kidney-T-cells-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	STK17B PITPNC1 SLC38A1 JAK3 STK10 GPR171 CCND3 OXNAD1	2.22e-05	193	267	8	5b84fa640cf30dea55fde53b810f850ff946d253
ToppCell	Children_(3_yrs)-Immune-natural_killer_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	ABHD17A PITPNC1 IL18RAP SLC38A1 STK10 PREX1 CCND3 CD38	2.22e-05	193	267	8	1cb666375bc4e1b11a146d20896c9b5ae6fd0887
ToppCell	nucseq-Epithelial-Epithelial_Alveolar\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DNAH14 PTPRK PTPRM ATF7IP2 DLG2 WWC1 SHROOM3 CEP70	2.30e-05	194	267	8	53f3e49e91b1096f3226010e2de767efb490dfe4
ToppCell	3'-Broncho-tracheal-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.3.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SPAG1 TTLL9 AK9 DLEC1 CFAP47 EFCAB6 AGBL4 HYDIN	2.30e-05	194	267	8	4a2c127c90d1fefe604fcb9e796577d21b489dd6
ToppCell	Adult-Immune-T_lymphocyte-D231\|Adult / Lineage, Cell type, age group and donor	STK17B PITPNC1 IL18RAP SLC38A1 JAK3 GPR171 PREX1 OXNAD1	2.30e-05	194	267	8	5c1dca33f382f37a7deb23e573578343c3b54986
ToppCell	Immune-T_lymphocyte\|World / Lineage, Cell type, age group and donor	STK17B PITPNC1 SLC38A1 JAK3 STK10 GPR171 CCND3 OXNAD1	2.30e-05	194	267	8	f47fa18c87b35a3960557f8169ff7830dd6ecb80
ToppCell	Children_(3_yrs)-Immune-T_lymphocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	PITPNC1 IL18RAP SLC38A1 JAK3 STK10 GPR171 CCND3 OXNAD1	2.30e-05	194	267	8	3d6f2d190dd50804afea299957cc44c2bb756134
ToppCell	human_hepatoblastoma-NK.T_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	STK17B IL18RAP SLC38A1 JAK3 RFTN1 GPR171 PREX1 CCND3	2.30e-05	194	267	8	997b02a22d7c89a8fd5615bb79a2a8a34fc3fee6
ToppCell	IPF-Multiplet-Multiplet\|IPF / Disease state, Lineage and Cell class	PTPRK TEKT1 WWC1 CFAP47 SHROOM3 ODAD2 AGBL4 HYDIN	2.39e-05	195	267	8	fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCell	IPF-Endothelial-Lymphatic\|Endothelial / Disease state, Lineage and Cell class	NPAS3 TNFRSF11A ADD3 NRP2 SLC38A1 CD38 PDE7B SMAD1	2.39e-05	195	267	8	de88e9d22044b4b3e29676ad02b3e9299cc920ad
ToppCell	Children_(3_yrs)-Immune-monocyte-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	STK17B STAB1 STK10 FMN1 TBC1D1 PREX1 KYNU CCND3	2.39e-05	195	267	8	81a28289eda1a8a1a31b7357106f64ac5000e172
Drug	Enkephalin, Ala(2)-MePhe(4)-Gly(5)-	ADORA1 OPRD1 OPRK1 OPRM1 MAPK1	5.41e-07	15	263	5	ctd:D020875
Drug	U 69593	OPRD1 OPRK1 OPRM1 MAPK1	1.17e-06	8	263	4	ctd:C045444
Drug	TRK 820	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:C111212
Drug	Oxycodone	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00497
Drug	Hydromorphone	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00327
Drug	Codeine	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00318
Drug	Carfentanil	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB01535
Drug	Morphine	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00295
Drug	Hydrocodone	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:D006853
Drug	3-Methylfentanyl	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB01571
Drug	Heroin	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB01452
Drug	3-Methylthiofentanyl	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB01439
Drug	morphine-7,8-oxide	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	CID005491901
Drug	Levorphanol	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:D007981
Drug	Levallorphan	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:D007977
Drug	Buprenorphine	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00921
Drug	Levorphanol	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00854
Drug	Remifentanil	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00899
Drug	Nalbuphine	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00844
Drug	Fentanyl	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00813
Drug	Sufentanil	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00708
Drug	Propoxyphene	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00647
Drug	Butorphanol	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB00611
Drug	Butorphanol	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:D002077
Drug	cyclorphan	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:C084603
Drug	Alvimopan	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	DB06274
Drug	dextrallorphan	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:C044130
Drug	14-phenylpropoxymetopon	OPRD1 OPRK1 OPRM1	1.52e-06	3	263	3	ctd:C478565
Drug	NSC76436	CYP2C19 CYP2C9 OPRD1 OPRK1 OPRM1	2.66e-06	20	263	5	CID000002828
Drug	Dynorphins	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	ctd:D004399
Drug	AC1L5BQM	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	CID000174892
Drug	Diprenorphine	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	DB01548
Drug	Dmt-NMe-Ala-Aba-Gly-NH2	OPRD1 OPRM1 MAPK1	6.04e-06	4	263	3	ctd:C569763
Drug	3B-b	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	CID000533975
Drug	phenylalanyl-cyclo(cysteinyltyrosyl-tryptophyl-ornithyl-threonyl-penicillamine)threoninamide	OPRD1 OPRM1 MAPK1	6.04e-06	4	263	3	ctd:C049352
Drug	Naltrexone	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	DB00704
Drug	Methadyl Acetate	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	ctd:D008692
Drug	7-hydroxymitragynine	OPRD1 OPRK1 OPRM1	6.04e-06	4	263	3	ctd:C482678
Drug	Aconitine	CYP2C19 CYP2C9 OPRD1 OPRM1 MAPK1	8.71e-06	25	263	5	ctd:D000157
Drug	Tolbutamide	CYP2C19 CYP2C9 CYP2C18 ALB CCND3	8.71e-06	25	263	5	ctd:D014044
Drug	Dihydromorphine	OPRD1 OPRK1 OPRM1	1.50e-05	5	263	3	DB01565
Drug	Naloxone	OPRD1 OPRK1 OPRM1	1.50e-05	5	263	3	DB01183
Drug	oxymorphamine	OPRD1 OPRK1 OPRM1	1.50e-05	5	263	3	CID000134844
Drug	Sc 39566	OPRD1 OPRK1 OPRM1	1.50e-05	5	263	3	CID000130018
Drug	NSC117862	CYP2C19 CYP2C9 OPRD1 OPRK1 OPRM1	2.23e-05	30	263	5	CID000003648
Drug	4',5-dihydroxydiclofenac	CYP2C19 CYP2C9 CYP2C18	2.97e-05	6	263	3	CID003052567
Drug	Etorphine	OPRD1 OPRK1 OPRM1	2.97e-05	6	263	3	DB01497
Drug	AC1L2OET	OPRD1 OPRK1 OPRM1	2.97e-05	6	263	3	CID000125331
Drug	NSC612111	OPRD1 OPRK1 OPRM1	2.97e-05	6	263	3	CID000163346
Drug	Loperamide	OPRD1 OPRK1 OPRM1	2.97e-05	6	263	3	DB00836
Drug	3'-hydroxydiclofenac	CYP2C19 CYP2C9 CYP2C18	2.97e-05	6	263	3	CID000112230
Drug	RX8008M	OPRD1 OPRK1 OPRM1	2.97e-05	6	263	3	CID000162443
Drug	Dextromethorphan	CYP2C19 CYP2C9 OPRD1 OPRK1 OPRM1	4.19e-05	34	263	5	ctd:D003915
Drug	Buprenorphine	OPRD1 OPRK1 OPRM1 MAPK1	4.69e-05	18	263	4	ctd:D002047
Drug	Pcl-dpdpe	ENPP1 OPRK1 OPRM1	5.15e-05	7	263	3	CID000159564
Drug	Tyr-ala-phe-gly	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID005487532
Drug	Enkephalin, D-Penicillamine (2,5)-	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	ctd:D020881
Drug	MET-CAMO	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID006450159
Drug	phenylmorphan	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID000146306
Drug	AC1L9PCU	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID000451042
Drug	N-cyclopropylmethylnorazidomorphine	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID005489191
Drug	Dextrorphan	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	ctd:D003917
Drug	2-mercaptoacetate	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	ctd:C017487
Drug	Dextropropoxyphene	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	ctd:D011431
Drug	beta-naltrexamine	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID005486948
Drug	NDTMB	OPRD1 OPRK1 OPRM1	5.15e-05	7	263	3	CID000134748
Drug	methadone	CYP2C19 CYP2C9 ALB OPRD1 OPRK1 OPRM1	6.66e-05	60	263	6	CID000004095
Drug	tifluadom	TRHR OPRD1 OPRK1 OPRM1	7.29e-05	20	263	4	CID000115208
Drug	alanine	SPOCK1 ADD1 SLC38A1 GFPT2 KYNU TAT LDHAL6B LDHC EDNRB OPRD1 OPRK1 ORC5	7.46e-05	269	263	12	CID000000602
Drug	AC1Q1ZY1	AVPR1A OPRD1 OPRK1	8.18e-05	8	263	3	CID000065964
Drug	ICI 204448	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID000003683
Drug	metazocine	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID000062518
Drug	AC1L1B1Q	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID000001246
Drug	DIPPA	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID000127914
Drug	11 beta-hydroxytestosterone	CYP2C19 CYP2C9 PREP	8.18e-05	8	263	3	CID000114920
Drug	Tyr-D-Ala-Gly-Phe-Leu-chloromethyl ketone	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID005492572
Drug	AC1Q3O0A	ADORA1 LDHAL6B LDHC	8.18e-05	8	263	3	CID000060880
Drug	14-methoxymetopon	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID005486940
Drug	KT-89	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID005748450
Drug	binaltorphimine	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID005484197
Drug	N-methyl nalorphine	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID005748235
Drug	AC1LBBLW	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID000579851
Drug	Oxymorphone hydrazone	OPRD1 OPRK1 OPRM1	8.18e-05	8	263	3	CID009577748
Drug	beta-Neoendorphin	OPRD1 OPRK1 OPRM1 PREP	8.92e-05	21	263	4	CID000122260
Drug	acetylmethadol	LAMA2 OPRD1 OPRK1 OPRM1	8.92e-05	21	263	4	CID000010517
Drug	indomethacin, USP; Down 200; 20uM; MCF7; HG-U133A	STK17B RIPK2 AP1B1 FBXO42 DOCK9 LAMA2 SETD4 ECPAS OPRD1 KBTBD4	9.93e-05	196	263	10	262_DN
Drug	AC1L1IMA	CYP2C19 CYP2C9 OPRD1 OPRK1 OPRM1	1.06e-04	41	263	5	CID000004639
Drug	NSC35549	CYP2C19 OPRD1 OPRK1 OPRM1	1.08e-04	22	263	4	CID000411697
Drug	Picrotoxin	TRHR LDHC EDNRB OPRK1 OPRM1 CCND3 SMAD1	1.10e-04	94	263	7	ctd:D010852
Drug	pyridoxine	ALB GFPT2 KYNU TAT TCN2 LDHC TKT	1.18e-04	95	263	7	CID000001054
Drug	ethanol	CYP2C19 TNFRSF11A ASIC5 CHRNA1 JAK2 ADORA1 JAK3 ALB TAT ANKK1 POLE LDHAL6B LDHC OPRD1 OPRK1 OPRM1 GSTM1 EEF2 CACNA2D4 TKT UTP4 PRKAG1 MAPK1	1.18e-04	837	263	23	CID000000702
Drug	Dam K	OPRD1 OPRK1 OPRM1	1.22e-04	9	263	3	CID005487344
Drug	4,5-dihydropyrazole-1,5-dicarboxylic acid 1-((4-chlorophenyl)-amide) 5-(2-oxo-2H-(1,3')bipyridinyl-6'-yl)-amide	CYP2C19 CYP2C9 CYP2C18	1.22e-04	9	263	3	ctd:C545880
Drug	Tramadol	OPRD1 OPRK1 OPRM1	1.22e-04	9	263	3	DB00193
Drug	Fluorescein	CYP2C19 CYP2C9 ALB	1.22e-04	9	263	3	ctd:D019793
Drug	meptazinol	OPRD1 OPRK1 OPRM1	1.22e-04	9	263	3	CID000041049
Drug	Acenocoumarol	CYP2C19 CYP2C9 CYP2C18	1.22e-04	9	263	3	ctd:D000074
Drug	Syndyphalin	OPRD1 OPRK1 OPRM1	1.22e-04	9	263	3	CID000174117
Drug	AC1LD4H9	OPRD1 OPRK1 OPRM1	1.22e-04	9	263	3	CID000611919
Drug	M 285	OPRD1 OPRK1 OPRM1	1.22e-04	9	263	3	CID000020435
Disease	X-21258 measurement	CYP2C19 CYP2C9 CYP2C18	6.53e-07	3	257	3	EFO_0800802
Disease	Drug Withdrawal Symptoms	ADORA1 PER3 SMURF1 OPRD1 OPRK1 MAPK1 SMAD1	7.21e-07	58	257	7	C0086189
Disease	Withdrawal Symptoms	ADORA1 PER3 SMURF1 OPRD1 OPRK1 MAPK1 SMAD1	7.21e-07	58	257	7	C0087169
Disease	Substance Withdrawal Syndrome	ADORA1 PER3 SMURF1 OPRD1 OPRK1 MAPK1 SMAD1	7.21e-07	58	257	7	C0038587
Disease	liver cancer (implicated_via_orthology)	JAK2 POLE ACOT12	2.60e-06	4	257	3	DOID:3571 (implicated_via_orthology)
Disease	colon adenocarcinoma (is_implicated_in)	JAK2 UBR5 KDM6A MAPK1 MAP2K7	2.73e-06	26	257	5	DOID:234 (is_implicated_in)
Disease	myocardial infarction (implicated_via_orthology)	AVPR1A JAK2 EDNRB OPRD1 OPRK1 MAPK1	2.42e-05	66	257	6	DOID:5844 (implicated_via_orthology)
Disease	Idiopathic pulmonary hypertension	TBX4 EIF2AK4 SMAD1	5.28e-05	9	257	3	C0152171
Disease	Nephroblastoma	DLG2 TCN2 NBAS	7.49e-05	10	257	3	Orphanet_654
Disease	X-14473 measurement	CYP2C19 CYP2C18	7.56e-05	2	257	2	EFO_0021370
Disease	level of UL16-binding protein 6 in blood serum	ULBP2 RAET1L	7.56e-05	2	257	2	OBA_2043185
Disease	platelet component distribution width	MTPN TRANK1 USP7 DLEC1 USP15 PREX1 ALG12 KYNU USP49 DOCK9 BTBD2 CCND3 TLN1 DOCK7 NUMB EIF2AK4 AGBL2 MYBPC1	1.24e-04	755	257	18	EFO_0007984
Disease	Huntington disease, disease progression measurement	ADD1 EFR3A PTPRM MSH3	1.29e-04	30	257	4	EFO_0008336, MONDO_0007739
Disease	hypertension (implicated_via_orthology)	TRHR ADD1 ADD3 MTPN ADORA1 KYNU EDNRB	1.35e-04	128	257	7	DOID:10763 (implicated_via_orthology)
Disease	S-warfarin to R-warfarin ratio measurement	CYP2C19 CYP2C9 CYP2C18 B3GALT5 EFR3A DLEC1	1.87e-04	95	257	6	EFO_0803331
Disease	hepatocellular carcinoma (is_implicated_in)	CYP2C19 SPOCK1 RYR3 SLC38A1 ALB KDM6A GSTM1 PNPLA3	1.99e-04	181	257	8	DOID:684 (is_implicated_in)
Disease	S-warfarin measurement	CYP2C19 SPOCK1 RFTN1 FMN1 TBC1D1 EIF2AK4	2.10e-04	97	257	6	EFO_0803323
Disease	2-oxo-hept-3-ene-1,7-dioate hydratase activity	TBX4 EIF2AK4 SMAD1	2.21e-04	14	257	3	C1150929
Disease	Cocaine Dependence	ANKK1 SMURF1 OPRD1 OPRK1 OPRM1 MAPK1 SMAD1	2.25e-04	139	257	7	C0600427
Disease	Hypotension, Orthostatic	OPRD1 OPRM1	2.25e-04	3	257	2	C0020651
Disease	spastic quadriplegic cerebral palsy 3 (implicated_via_orthology)	ADD1 ADD3	2.25e-04	3	257	2	DOID:0081361 (implicated_via_orthology)
Disease	cyclo(leu-pro) measurement	CYP2C19 CYP2C18	2.25e-04	3	257	2	EFO_0800676
Disease	rectum adenocarcinoma (is_marker_for)	KDM6A EEF2	2.25e-04	3	257	2	DOID:1996 (is_marker_for)
Disease	polycythemia vera (is_implicated_in)	JAK2 GSTM1	2.25e-04	3	257	2	DOID:8997 (is_implicated_in)
Disease	Idiopathic pulmonary arterial hypertension	TBX4 EIF2AK4 SMAD1	3.36e-04	16	257	3	C3203102
Disease	Familial primary pulmonary hypertension	TBX4 EIF2AK4 SMAD1	4.06e-04	17	257	3	C0340543

Protein segments in the cluster

Peptide	Gene	Start	Entry
SVDHLKVCPRYTAVL	TADA3	16	O75528
HRCYDLIPTSSKLVV	PRKAG1	36	P54619
ISELYVRDNCHPFKA	COX18	156	Q8N8Q8
HECYAKVFDEFKPLV	ALB	391	P02768
IEKLCIYTDHAVSPR	CCND3	121	P30281
FHPKELLECAFDIVT	EIF2AK4	1151	Q9P2K8
LHCGIPEDKLSQVYI	EIF2AK4	1211	Q9P2K8
PSCHKPSILTYIAIF	ADORA1	261	P30542
HAAIYSTRPDVKCVI	ADD3	216	Q9UEY8
LAENYCFDSIPKLIH	BMX	361	P51813
HKEERFLFPVYPLIC	ALG9	366	Q9H6U8
CIITARKHPDADSLY	AIMP1	161	Q12904
LCIYENKVTPLHFLV	ANKK1	356	Q8NFD2
CHKSFDPVLDKRIEY	COQ3	186	Q9NZJ6
LEKRAYICAHPLDRT	ACAD9	606	Q9H845
FLATVKAHPKYLSCI	CCNI	76	Q14094
GRKYVISHKEEVPLC	ACOT12	326	Q8WYK0
SHGLALYERCPKAVE	ABHD17A	261	Q96GS6
IVACHFIKPRTLLDY	B3GALT5	281	Q9Y2C3
YLRICLLHPVQKTAF	EDNRB	251	P24530
LSLKCRAPEVSQHVY	AP1B1	926	Q10567
KEHCASNIYVPIRLP	ACTR5	566	Q9H9F9
FCIKHLISYLIPDLP	ANO4	896	Q32M45
TLLHFLVEICEEKYP	DIAPH3	881	Q9NSV4
EAPYFLPEHIFRDKC	EFR3A	631	Q14156
AQFLCDIKHVVLYPL	AIP	86	O00170
ATVHLVICPYTKVEE	ALG12	21	Q9BV10
VLKCDINIPIAYHFL	CCNB3	1251	Q8WWL7
ETVLARCVKYTEIHP	CD38	61	P28907
KCVQYDEHVISPKEF	GMEB2	116	Q9UKD1
PLSLDHFKECTVEYE	IL13RA2	56	Q14627
CFKHPESVSYAIALL	RBM11	56	P57052
KCRQYYPVTIPLHVS	RFTN1	291	Q14699
QDPTRFKSIHCLLYP	RFNG	301	Q9Y644
HKPITELCYISFCLP	FMN1	11	Q68DA7
HYLCKEVAPPAVLEN	JAK2	381	O60674
CQDPTIFEERHLKYI	JAK3	811	P52333
VPDERFDFLCQYHKP	OLA1	66	Q9NTK5
KCELVLIHTYPVGED	INTS13	201	Q9NVM9
PAIFKSYCEIIVTHF	CHRNA1	141	P02708
HRPKYALLDECTSAV	ABCD1	621	P33897
QCVRTYKALHPDELT	ARHGEF19	721	Q8IW93
LKIPHFGYCDEIDLT	DBT	271	P11182
VCHFSPLKSDQDYIL	PA2G4	86	Q9UQ80
FLSPYQEHKTAALVC	FBXO42	61	Q6P3S6
VAIKKISPFEHQTYC	MAPK1	51	P28482
LFVTHYPPVCELEKN	MSH3	1006	P20585
SNIIKHYFCDIVPLI	OR8D4	171	Q8NGM9
SVINHFYCADPPLIK	OR5M11	171	Q96RB7
DRYIAVCHPVKALDF	OPRM1	166	P35372
PTTDDPALLYHKCQV	PAQR7	231	Q86WK9
LIKFCYFQEPESLPH	IL18RAP	511	O95256
VCARHLKLFGYEPTI	NAXE	126	Q8NCW5
EKVTKVHLSICFPEY	GNAT3	276	A8MTJ3
VEVDPTTHCYGLFIK	MAGEB16	171	A2A368
YHCPEAPLEAKDVIL	TAT	126	P17735
ALKSILCRTPGEFYH	TAT	326	P17735
TKHFQTLYVEPGLCL	LSG1	421	Q9H089
CKPLVPREHQFYETL	IP6K2	41	Q9UHH9
SLSVERYLAICHPFK	NTSR1	161	P30989
YPALHQKTLRVDVCT	WWC1	736	Q8IX03
KAAPVSCFKHVPLYD	L3MBTL2	191	Q969R5
FHYLLIKDGCRVPAV	CCL19	46	Q99731
YKRELTTPLCIAAAH	ASB18	116	Q6ZVZ8
DITKHYLRLTCAPDP	LENG8	556	Q96PV6
PIKVLVVYPSEICFH	IL17RB	331	Q9NRM6
VLYVDPSFCRAKEIH	KDM6A	156	O15550
EEPIYKTSCALTIHA	ECPAS	1451	Q5VYK3
QEKCHSPFRIIPYLI	PER3	221	P56645
CLTVVEKIHSGYEAP	PER3	251	P56645
VRLCKDDPKFHSYVS	PLXNA2	281	O75051
YSPHCKLIIVSNPVD	LDHAL6B	176	Q9BYZ2
DLDVVLKSHDCPYIV	MAP2K7	166	O14733
KRLPFCLTNIVPHSY	OR52B2	166	Q96RD2
DRYVAICKPLHYLTI	OR4F6	121	Q8NGB9
DRFIAICKPLHYSTI	OR4K1	121	Q8NGD4
ICKPLHYASVISPQV	OR4K2	126	Q8NGD2
DRYVAICKPLHYLTI	OR4K3	121	Q96R72
TLHYECIVLVKQFRP	NUDT5	71	Q9UKK9
CEKPLTRLHVTYEGT	PARG	711	Q86W56
CFIEREVPFHLKAVY	PCDH9	401	Q9HC56
HCYLKEPKLASFLTP	PDE7B	186	Q9NP56
YDICPKVKSTNFLHV	PNPLA3	191	Q9NST1
LTHSCKIYRIQEPGF	GPR171	116	O14626
IAKLVHFQGYPCELL	INTS2	1011	Q9H0H0
YPLQLKFLETVHTLC	GXYLT2	396	A0PJZ3
PLELELQKTVHTYCG	GXYLT1	401	Q4G148
CPYTKHQTLELEKEF	HOXA9	211	P31269
PEKYPHNLDCTFTIL	NRP2	166	O60462
FYIQTPEECHVSLKE	MPHOSPH9	96	Q99550
HIKTSFCAPGEYLLR	KCNH4	571	Q9UQ05
IPAIVHYSPDCKILV	LDHC	121	P07864
HYSPDCKILVVSNPV	LDHC	126	P07864
PASLSCYKVFHAERI	LY75	651	O60449
EVICTSFYSKIHPLE	LAMA2	196	P24043
CLYQDFRIPLSPVHK	ENPP1	711	P22413
TEYLFLLCILTKPHA	MICU3	221	Q86XE3
PICTGETAYLKLHFR	AP5M1	421	Q9H0R1
KDVPSRIECPLIYHL	POLE	611	Q07864
CPYTKHQTLELEKEF	HOXA10	341	P31260
VYLKSHFNPCVGVLI	PRSS37	31	A4D1T9
VFCKEYRVTIVADHP	HMGXB4	416	Q9UGU5
IPHLLKVACADTSRY	OR2AG1	181	Q9H205
PKYTDIVLSFLLCHP	MROH8	416	Q9H579
CNSFYIPRHVKKEEE	GREM2	101	Q9H772
VKCVSTPFYPRIVDH	NBAS	2301	A2RRP1
RLHTTYEFPVVCFVK	OOSP4B	86	A0A2R8Y4Y8
SIDKRHCSLVYVPEE	LRRC1	16	Q9BTT6
KSVTICDYLPPHLVI	NDUFA10	191	O95299
LVEEPLFFSKCHTVY	MEI1	351	Q5TIA1
RYIAVCHPVKALDFR	OPRD1	146	P41143
RDHISKETLFYICGP	OXNAD1	271	Q96HP4
DPYVAICKPLHYTVI	OR5AK2	121	Q8NH90
FLSPGIIYHCDLTKE	PREP	401	P48147
VRCPSVIEFGKYEIH	KAT6A	506	Q92794
CVNPIVYALVSKHFR	GALR2	286	O43603
AVFHIKTCRPFSIEP	HYDIN	231	Q4G0P3
TLPICHFDLKDSDYI	HYDIN	3946	Q4G0P3
PVSAFPIHCFDYEVK	IL5RA	261	Q01344
LKTHDICPSRNYILV	AWAT2	91	Q6E213
LPHAVTCDVKFRNYL	CYP2C19	366	P33261
YEEFKLHLPACVTEN	DOCK6	616	Q96HP0
LYKAVLPVTCHRDSF	DOCK7	2116	Q96N67
ILTAIHCFPYVKKRI	DOCK9	1921	Q9BZ29
FAYKTIELPHTVDCL	GFPT2	631	O94808
VFAYLCKRVPHTVLD	CEP70	196	Q8NHQ1
CIHYDRKAPDTFKVA	GCNT4	161	Q9P109
FYSALLRIQPKIVHC	EFCAB6	1421	Q5THR3
VHYIEPCFKGILVQA	CACNA2D4	336	Q7Z3S7
IYCITDIDPDHRKLS	CACNA2D4	686	Q7Z3S7
LFHPKYTGEDLTCTV	FNDC3B	521	Q53EP0
EECSPKQLHEIPAFY	FAM117B	481	Q6P1L5
KKYAVPALEAHCVEF	BTBD1	156	Q9H0C5
IKKHFEEAYPNCTVL	TMEM63B	256	Q5T3F8
VLTPYYHKVDFECIL	FASTKD1	721	Q53R41
CPYTKHQTLELEKEF	HOXD10	271	P28358
HPIACVLREYLVFKI	AGBL4	251	Q5VU57
NRHYKTILKESFPCI	AGBL2	521	Q5U5Z8
KYFSCVSPVLDHIEF	ASIC5	346	Q9NY37
PYLSPDILEEKHCEF	ATL3	376	Q6DD88
RVPISHKCAYIEFKE	DNAH14	2036	Q0VDD8
ILSYPKDFTCVHQAL	SERPING1	196	P05155
INPKCAPVESYHLFL	ATF7IP2	601	Q5U623
HPETLCPYDFLKIQT	MASP2	236	O00187
TTPELLLKTFDHYCE	DYNC1H1	2626	Q14204
FLCVVSKELHNTPYG	KCTD5	201	Q9NXV2
LPHAVTCDVKFKNYL	CYP2C18	366	P33260
PRHYSPVECDKSFLL	DLG2	361	Q15700
IHLPSPVTAQKYRCE	EEF2	356	P13639
LCLTIHPLKDYVATG	EML5	731	Q05BV3
LPHAVTCDIKFRNYL	CYP2C9	366	P11712
DILEKVSVHCPVFDY	EIF2B2	301	P49770
REICKDLLGPVHYST	HIRA	956	P54198
PLTIDRYIAVCHPLK	GPR139	121	Q6DWJ6
ICLQPRLHFDGKYIV	FBXW2	326	Q9UKT8
TAKKYAVPALEAHCV	BTBD2	196	Q9BX70
VLSPEILHKVECTGY	DLEC1	1411	Q9Y238
LPIVLHTKEAECAYT	SLC13A1	26	Q9BZW2
HIGEVFCYLPLRIKT	SACS	1866	Q9NZJ4
VKYCHADIPREVAVK	SACS	2481	Q9NZJ4
YLPKKVVSFECTLHD	CFAP47	1871	Q6ZTR5
VATYRKTHLCDVEIP	NIT1	156	Q86X76
FLSDHPYLVCEETAK	CDC37L1	181	Q7L3B6
YLPPLCKNTEDRHVF	PHKA2	676	P46019
PKVEHLIGYEVFECT	LRRC8D	341	Q7L1W4
QVLSYPCDKSPHFLR	PTPRK	186	Q15262
TTEILKCYPVPIHFQ	PTPRM	636	P28827
IPHFYCDPSALLKLA	OR1N2	191	Q8NGR9
RYIAVCHPVKALDFR	OPRK1	156	P41145
DRYIAVCKPLHYVVI	OR2G3	121	Q8NGZ4
KCSFPVKYLGHVEVD	NUMB	36	P49757
RLVSILNKLEFYCHP	HSFX1	181	Q9UBD0
FYKCPVRLHLQTVPS	MRPS24	146	Q96EL2
KLNSPEVCHFGYIIT	AK9	101	Q5TCS8
EKYLEQCEHSFLPPT	SNX13	56	Q9Y5W8
LKLHCTVPAYNFPVT	UTP4	516	Q969X6
PLCKVIRFNIDYTIH	DROSHA	616	Q9NRR4
DVPQKCTLHAEPYLL	RNF207	151	Q6ZRF8
CTLHAEPYLLFSTDK	RNF207	156	Q6ZRF8
LQTKHPDIYCITDFA	SPHKAP	916	Q2M3C7
RILCPLDPKHTVYED	TRMT13	56	Q9NUP7
IPTEQKIEFCISYHA	PPP1R3C	226	Q9UQK1
PKECPAIDYTRHTLD	MOB4	116	Q9Y3A3
VVETCFIPKTHLYDA	SLC9C1	971	Q4G0N8
IERYIAICHPIKAQF	TRHR	121	P34981
TRCFEHYEKGSVPVL	PTAFR	171	P25105
CQSIYPLHDVFVRKV	RPS3A	201	P61247
RPHEVLLCSDLVKAY	CHCHD6	211	Q9BRQ6
ETDKCHVKPYVLPFA	KBTBD4	406	Q9NVX7
EICYVLVKPHDGETL	ODAD2	246	Q5T2S8
RHLAVLNFPKYCEPV	ORC5	226	O43913
EALKYIGAHCPELVT	FBXL20	211	Q96IG2
PEIVHASRCEKYVET	PNLDC1	331	Q8NA58
YDVLDLHRIFEPKCL	GSTM1	161	P09488
KDFLAALEYCLHPEP	PREX1	111	Q8TCU6
CHVSAYEKSFPIKPV	SENP1	141	Q9P0U3
LAKSCPRVINLHEVY	STK17B	86	O94768
NPHACVYVSREILVK	SETD4	291	Q9NVD3
PEATAKYVPSKVHFC	SHROOM3	546	Q8TF72
KEPLHITETCLAYRE	TEKT1	106	Q969V4
LTPVDIVGKRCYHFI	NPAS3	356	Q8IXF0
PYCIAIGDVKKLVHF	WDR17	881	Q8IZU2
ELHIPKASCVPVYRA	SARDH	736	Q9UL12
KAHTCFNRIDIPPYE	SMURF1	721	Q9HCE7
CINPYHYKRVESPVL	SMAD1	121	Q15797
LNHKTYIDLIFPDCL	TCN2	296	P20062
ACDPYLLPHIRKSVS	TLK2	736	Q86UE8
AIYAARPDVKCVVHI	ADD1	226	P35611
IYVEDKHKILYCEVP	CHST9	206	Q7L1S5
KLVVPEYSIHGLFCL	CNIH2	66	Q6PI25
KLVLPEYSIHSLFCI	CNIH3	66	Q8TBE1
FADYPCHTVATDILK	CNOT1	421	A5YKK6
FFPQYPDKELHITAC	CNOT1	901	A5YKK6
ILPKCRTSYEEFTHK	PRPF8	1196	Q6P2Q9
RVAHVEVAPFYTCKK	XPR1	176	Q9UBH6
EPELHPAVCYRIKSL	TBPL1	131	P62380
YSHLEAFVPCNKETL	UBN2	506	Q6ZU65
LASVCERPHYKNLFE	CSE1L	321	P55060
VGYCAHKPEVIFRLE	ZNF33B	51	Q06732
QFDIYLKADCPHPIR	TRAPPC11	606	Q7Z392
LEHVYSGEKPVLDIC	ZNF19	431	P17023
DPLKYFIIQDRCPHT	UMOD	516	P07911
IFVLYHCENAKTPKE	MINPP1	416	Q9UNW1
PLLSAVYEGHVSCVK	MTPN	71	P58546
FKKEHPDRFIECYIA	TKT	351	P29401
CEAIAKSILTQPHLY	SEC16A	1826	O15027
KVLLPLVDQYFTSHC	RYR3	2861	Q15413
LRACKEAAYHPEVAP	TLN1	2216	Q9Y490
FIVYPPESAVHCSLK	ARHGAP23	61	Q9P227
ICSALPTIPYHKLAD	RIPK2	6	O43353
YAPICTLEFLHDPIK	SFRP4	81	Q6FHJ7
PIEHLDFKYIEKCSD	SPAG1	21	Q07617
EIEILATCDHPYIVK	STK10	81	O94804
YSSPLLIHEQFGCIK	STAC	171	Q99469
PSYFACLIKEDAVHR	TBC1D1	111	Q86TI0
EYTCSFLPKFSIHIE	PITPNC1	96	Q9UKF7
IPLDCCRLVKYDEFH	USP47	651	Q96K76
LSLEFPERYHCIEKG	USP49	471	Q70CQ1
DYQTALCVSRKHLLP	SPOCK1	101	Q08629
PKLPSYSTHELCERF	USP25	1026	Q9UHP3
IIPVCLREKFRHSSY	USP15	566	Q9Y4E8
HSLCYDITVIPKFRP	RAET1G	31	Q6H3X3
SVKLDIFPKECVYIH	STAB1	681	Q9NY15
YCRLHSLFTPVIRDK	PREX2	486	Q70Z35
HSLCYDITVIPKFRP	RAET1L	31	Q5VY80
TADRYIAVCHPLKTL	AVPR1A	146	P37288
KPYECNEHSKVFRVS	ZNF480	201	Q8WV37
PCEYHLFVEEFRKNP	TTLL9	146	Q3SXZ7
YCAKEFRKPSDLVRH	ZNF236	486	Q9UL36
LTFLEYCIEKIHFIP	SLC9C2	576	Q5TAH2
YCIEKIHFIPPESNT	SLC9C2	581	Q5TAH2
LIDIVPADDHRYKFC	TBX4	116	P57082
ALSCPHGRLTEEVYK	TRANK1	1316	O15050
HSLCYDITVIPKFRP	ULBP2	31	Q9BZM5
FTLYCPLHTQEVLKL	TRIM66	61	O15016
HREKFCYELTGEPLV	PRSS50	301	Q9UI38
IITALPTIYHCKDGE	TMX1	96	Q9H3N1
VSLVERKYSHYCLPP	TMEM271	146	A0A286YF58
YHRVDVIFCDKTIPN	USP7	791	Q93009
FCYLSVPLPISHKRV	USP11	481	P51784
FVCHPSVLPIYSELK	SLC38A1	286	Q9H2H9
PCTVHTRKKDLYDAV	USP6	906	P35125
AVKEDCKVHIRVYLP	WWC3	631	Q9ULE0
TSCDPLKIFLYHDGL	TTLL7	211	Q6ZT98
CYAVLVSLRHFPEKQ	TMEM145	331	Q8NBT3
LPVLDVCSLKHVAYV	UBR5	1936	O95071
VALQIAPPCTSEKHY	TNFRSF11A	26	Q9Y6Q6
GECLYIARKDHPQFL	UNC79	986	Q9P2D8
PGKVFVCDAYLQRHL	ZNF628	246	Q5EBL2
TLFLPHYASAKVCEE	HECTD3	826	Q5T447
HIKTSFCAPGEYLLR	KCNH8	566	Q96L42
HFRECFYIPKIQDLP	KYNU	41	Q16719
DCPVSLKKGYRHVLV	LRRIQ3	131	A6PVS8
SPEKIFHVIVAPCYD	NARF	216	Q9UHQ1
FHVIVAPCYDKKLEA	NARF	221	Q9UHQ1
SPYPRVKVDFALSCH	NADSYN1	296	Q6IA69
EIRPSTKYIFEHKGC	MYBPC1	291	Q00872
CVVKHPALEKDIRYS	NECTIN3	246	Q9NQS3