Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctiondihydropyrimidinase activity

DPYSL5 DPYS

3.26e-056302GO:0004157
GeneOntologyMolecularFunctionhydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides

DPYSL5 DPYS

2.58e-0416302GO:0016812
GeneOntologyMolecularFunctiondeath receptor binding

FASLG MADD

6.41e-0425302GO:0005123
HumanPhenoAbnormal hippocampus morphology

DPYSL5 CPA6 ZEB2

9.00e-0548103HP:0025100
HumanPhenoThick vermilion border

DPYSL5 HUWE1 ZEB2 USP9X MADD

9.55e-05279105HP:0012471
HumanPhenoAbnormal morphology of the limbic system

DPYSL5 CPA6 ZEB2

9.58e-0549103HP:0007343
DomainHydantoinase/dihydroPyrase

DPYSL5 DPYS

3.98e-056312IPR011778
Domain-

DPYSL5 DPYS

7.42e-0583122.30.40.10
DomainMetal-dep_hydrolase_composite

DPYSL5 DPYS

1.19e-0410312IPR011059
DomainAmidohydro_1

DPYSL5 DPYS

1.19e-0410312PF01979
DomainAmidohydro-rel

DPYSL5 DPYS

1.45e-0411312IPR006680
DomainMetal_Hydrolase

DPYSL5 DPYS

7.19e-0424312IPR032466
DomainARM-type_fold

HUWE1 PIK3CB USP9X PPP4R4

2.28e-03339314IPR016024
DomainARM-like

HUWE1 USP9X PPP4R4

9.96e-03270313IPR011989
Pubmed

Noxa controls Mule-dependent Mcl-1 ubiquitination through the regulation of the Mcl-1/USP9X interaction.

HUWE1 USP9X

4.61e-06431221907705
Pubmed

Deubiquitinase USP9X stabilizes MCL1 and promotes tumour cell survival.

HUWE1 USP9X

4.61e-06431220023629
Pubmed

USP9X destabilizes pVHL and promotes cell proliferation.

HUWE1 USP9X

1.15e-05631227517496
Pubmed

Molecular characterization of CRMP5, a novel member of the collapsin response mediator protein family.

DPYSL5 DPYS

1.15e-05631210956643
Pubmed

Mechanisms of MCL-1 Protein Stability Induced by MCL-1 Antagonists in B-Cell Malignancies.

HUWE1 USP9X

1.61e-05731236346691
Pubmed

Physiogenomic analysis of statin-treated patients: domain-specific counter effects within the ACACB gene on low-density lipoprotein cholesterol?

HTR7 FASLG PIK3CB GABRA4

2.52e-0519231420602615
Pubmed

Ubiquitin ligase TRIM71 suppresses ovarian tumorigenesis by degrading mutant p53.

HUWE1 USP9X

4.21e-051131231570706
Pubmed

The ubiquitin ligase TRIM25 targets ERG for degradation in prostate cancer.

HUWE1 USP9X

6.95e-051431227626314
Pubmed

Selection system for genes encoding nuclear-targeted proteins.

NOL4 ZEB2

6.95e-05143129853615
Pubmed

Loss of p53 Causes Stochastic Aberrant X-Chromosome Inactivation and Female-Specific Neural Tube Defects.

HUWE1 USP9X

8.02e-051531230970248
Pubmed

Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication.

DPYSL5 MPP2 MICAL3 AQR

1.14e-0428331418854154
Pubmed

Ubiquitination regulates ER-phagy and remodelling of endoplasmic reticulum.

HUWE1 USP9X

1.76e-042231237225996
Pubmed

The E3 ubiquitin ligases, HUWE1 and NEDD4-1, are involved in the post-translational regulation of the ABCG1 and ABCG4 lipid transporters.

HUWE1 TUBGCP2

3.99e-043331226296893
Pubmed

Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts.

FADS2 MADD

4.24e-043431219060911
Pubmed

5-hydroxytryptamine synthesized in the aorta-gonad-mesonephros regulates hematopoietic stem and progenitor cell survival.

HTR7 FASLG

4.49e-043531228031476
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

MICAL3 ZEB2 AQR MADD

4.53e-0440731412693553
ToppCellwk_08-11-Epithelial-PNS-SST+_neuron|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

DPYSL5 PLPPR5 DPYS HTR7

9.05e-06191314df2bef74a54f4c23c99bd3b93225fd36bcd90723
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP8B3 TMC5 FASLG

2.53e-05823131ed7d7f70f00d6e280cd59c54e710bb724c8b50b
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr-Inhibitory_Neuron.Chat-Gad1Gad2-Slc17a8.Ngfr_(Globus_Pallidus/Nucleus_Basalis_(GP/NB),_cholinergic)-|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP8B3 TMC5 FASLG

2.53e-0582313a5d3c5b7012d8ca7418670242d22aad3ed8c5191
ToppCellGlobus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Ngfr|Globus_pallidus / BrainAtlas - Mouse McCarroll V32

ATP8B3 TMC5 FASLG

2.53e-0582313cefd8c6f60ef27fb8823faddca1cf8bbd636f474
ToppCellThalamus-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Slc17a7-Tac2-Excitatory_Neuron.Slc17a7.Tac2.Htr2c_(Lateral_habenula)|Thalamus / BrainAtlas - Mouse McCarroll V32

CPA6 ATP8B3 TM6SF2

4.44e-05993133dd31ed90bd1655cad954045afaef50de889008b
ToppCellprimary_visual_cortex-Neuronal-GABAergic_neuron-Sncg|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DPYSL5 ATP8B3 HTR7

1.07e-04133313840e8240db29cd21ed9830843c0fa6d65b8f300a
ToppCellCOVID-19-Fibroblasts-Mesothelial_FB|COVID-19 / group, cell type (main and fine annotations)

DPYS PPP4R4 GABRA4

1.27e-041413137e6dcccb74e7ee90b69dc91b59491b84f3a713c9
ToppCellfrontal_cortex-Neuronal-GABAergic_neuron-Sncg|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

DPYSL5 ATP8B3 HTR7

1.30e-04142313ed91d2ef4c346f7e1a5402846e2a34cee19c24d1
ToppCell15-Trachea-Immune-Immune|Trachea / Age, Tissue, Lineage and Cell class

ATP8B3 MIOX HTR7

1.41e-04146313ca722a89c6601e78f253d9484d01931f26161820
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

TMC5 MIOX PPP4R4

1.47e-041483139fe3c0a5904b8e9a0f28130f8d84d4f2a819b06c
ToppCellLPS-IL1RA-Epithelial_airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

1.88e-04161313472c354f5ee148b37a5dfb795e83348ecb1643f1
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-NK_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL5 TM6SF2 FASLG

1.95e-041633132e1c1193c04620cc187b1567dfba025beef1e4e1
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.02e-041653131a114eacaab598f755a173a3fed842ba91f689dd
ToppCellLPS-IL1RA-Epithelial_airway-Club_cells-Airway|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.02e-041653139cfd3c1d2c6d714fde83b90465f1f9741b0e50ce
ToppCellLPS-antiTNF-Epithelial_airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.05e-04166313eb942ed68677e55c46cb039046f45686d4062d7c
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.05e-041663131df4bdf7c773cbfa6c93d7a901f9cd3f3fe07a3d
ToppCellLPS-antiTNF-Epithelial_airway-Club_cells-Airway|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.05e-041663139628522e7af8f8edca733588a364ab2454ac5ca5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DPYSL5 DPYS TMC5

2.09e-0416731331633899aae852873a4887e72c621474b0a51a33
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells-Airway|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.17e-0416931386041be5d3aeab5b9269f7912791b944f325a1b4
ToppCellLPS-IL1RA+antiTNF-Epithelial_airway-Club_cells|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

TMC5 SDR16C5 PPP4R4

2.17e-041693138c96e1baa38ec5e777e627ab9dbce025e771f2c0
ToppCellMesenchymal_cells-Osteo-CAR|Mesenchymal_cells / Lineage and Cell class

PLPPR5 TM6SF2 ZEB2

2.36e-04174313430e3cd61bc2a471959faa40e817aa4dd7d82d28
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

KIAA0930 TUBGCP2 DSEL

2.36e-0417431309b091e24317c3f7bac043f04762a533e30793de
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 DPYS MIOX

2.44e-041763131595dbeee336a81e581325d63208ec6262664ee9
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 DPYS MIOX

2.48e-041773132f81b26be89cc2fd8eafadaf7eae3c6ad6521462
ToppCell3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid-cDC2|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

KIAA0930 MIOX PIK3CB

2.56e-04179313ce95b601bf17ae8167d382a105384b9e65e9407f
ToppCellfacs-Marrow-T-cells-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL5 HUWE1 GABRA4

2.65e-0418131357f0cc749ae8b6a3d77e2af31f9a6e4739c57049
ToppCellfacs-Marrow-T-cells-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DPYSL5 HUWE1 GABRA4

2.65e-04181313d01b35cc2fc57991a35be6a06cb7351fbabd9a11
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FADS2 TRAM1L1 TM6SF2

2.69e-04182313ebc812ed3f25839ea25f76b952c463d79a8325b1
ToppCellfacs-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

FADS2 TRAM1L1 TM6SF2

2.69e-0418231347ff6b4002a4167412c79210651316d1342503f9
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 DPYS MIOX

2.74e-0418331385446581999cd66b171c4f69b7eb8b0bbbaa8617
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_immature_neuronal_(2)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DPYSL5 NOL4 PLPPR5

2.74e-041833139dfb398b9995d562864fe688861a831ada0814cd
ToppCelldroplet-Kidney-nan-21m-Epithelial-Pecam____kidney_capillary_endothelial_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PLPPR5 TRAM1L1 GABRA4

2.74e-04183313f55081068213cc1cdb2acad58ff10f6b48b44c72
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 DPYS MIOX

2.78e-041843139434731f651820b05335085582960f08fbf895de
ToppCellkidney_cells-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ATP8B3 TMC5 SDR16C5

2.82e-041853134d0f3d86fab02c80093e62cb0c79c586c13c5412
ToppCell5'-GW_trimst-1-SmallIntestine-Neuronal-neurons_A-Branch_A3_(IPAN/IN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ATP8B3 PLPPR5 DPYS

2.82e-0418531394d0f283d63d932f310cc5a17ea893d71ba60f5e
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 DPYS MIOX

2.87e-04186313a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

NOL4 KIAA0930 MIOX

2.87e-04186313b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCellfacs-Lung-ENDOMUCIN-18m-Endothelial-Artery_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FADS2 TRAM1L1 TM6SF2

2.87e-041863135302399825f213d105ac70b91366a4513b732838
ToppCelldroplet-Heart-nan-18m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MPP2 ATP8B3 HTR7

2.92e-041873132591fe1552cd10925ad1d8d1f062a057ce6bdad9
ToppCell10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8|GI_small-bowel / Manually curated celltypes from each tissue

HUWE1 ZEB2 USP9X

2.96e-04188313ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

TMC5 SDR16C5 PPP4R4

2.96e-04188313ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellAdult|World / Lineage, Cell type, age group and donor

TMC5 SDR16C5 PPP4R4

3.01e-041893135cd285bfad973125d46d704fec18b21266a63379
ToppCelldroplet-Lung-nan-18m-Epithelial|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRPM6 TMC5 ZMYND12

3.05e-04190313b057bea6e55cef872290893b6e439bbcdcee2f2e
ToppCellPCW_05-06-Neuronal-Neuronal_postreplicative-neuro_neuronal_(6)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

DPYSL5 PLPPR5 DPYS

3.10e-041913133a5081dc542ac6262acfe5f8084a86616fee8082
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPA6 FADS2 ZEB2

3.10e-041913131caf726bd07fdca389e678fc16304a6ef1790423
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPA6 FADS2 ZEB2

3.10e-041913133d60c46bced2984c27a1fcf2910bc38b31fb0148
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPA6 FADS2 ZEB2

3.15e-041923134022f208eb5db760abd0aac782a25e8ab63efc64
ToppCellfacs-Pancreas-Endocrine-3m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NOL4 USP9X MADD

3.15e-041923135b7093d5af5ae7b0e6d3a464cc56272440ecedad
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

CPA6 FADS2 ZEB2

3.15e-041923139333aba0d04203ccccad78d82bf6359922f810a7
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A-Branch_A1_(iMN)|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL5 NOL4 PLPPR5

3.15e-04192313fe9297cb65234d9f511bab1a5dbf2679d5a4cd15
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMC5 SDR16C5 PPP4R4

3.20e-04193313fd4d3c0d7caf8a2fff5b3d901fc28d19a8163cdf
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-6|TCGA-Prostate / Sample_Type by Project: Shred V9

HUWE1 USP9X AQR

3.20e-04193313abd71b2cf667ef2b1c4d88acd0c1dd19a12ff659
ToppCellnucseq-Epithelial-Epithelial_Alveolar-AT2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

TMC5 SDR16C5 PPP4R4

3.20e-04193313f3cc7cfdbc164a4ed42f87647111522b7d393bcb
ToppCell3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_A|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL5 NOL4 PLPPR5

3.20e-04193313a189d46c39067b717509cd144e0225cc93d7731d
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

DSEL FASLG ZEB2

3.25e-04194313a8dc3336aa4ef497f6d26cede02ddac425e7c655
ToppCell5'-Adult-SmallIntestine-Epithelial-Tuft-related|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

TMC5 TM6SF2 GABRA4

3.30e-0419531323ab7e2a419377c05bab0e92a2457afbcd3d9e07
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 USP9X MADD

3.30e-041953133e519cffa6144a62b06124642a14c9ff39b76554
ToppCelldroplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HUWE1 USP9X MADD

3.30e-041953137796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell3'-GW_trimst-1-SmallIntestine-Neuronal-neurons_B-Branch_B2_(eMN)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DPYSL5 PLPPR5 HTR7

3.45e-0419831385881637641d8996be2edc65c4bceff0433135e7
ToppCellParenchymal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_CHIT1|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA0930 HTR7 ZEB2

3.45e-041983136a4161680b46b2c12353a693c403b5a4bb3da03f
ToppCellLPS_anti-TNF-Epithelial_airway-airway_epithelial-Airway-Club|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

NOL4 TMC5 SDR16C5

3.45e-041983136712216c5a7fd86b68fd45b0ff7794975f19774e
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

TMC5 SDR16C5 PPP4R4

3.45e-04198313f948391296c261c473d339069a6d0f20ccd6f38f
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW10-Neuronal-Neurons|GW10 / Sample Type, Dataset, Time_group, and Cell type.

NOL4 TRAM1L1 ZEB2

3.50e-041993130c5a5fbb174a013be10961f0db65c65c797ab4af
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Neuronal|3_mon / Sample Type, Dataset, Time_group, and Cell type.

NOL4 PLPPR5 ZEB2

3.50e-041993131029f3458b7fda464aa0e7ef06e081e2618c1388
ToppCellBrain_organoid-organoid_Paulsen_bioRxiv-3_mon-Neuronal-PNs|3_mon / Sample Type, Dataset, Time_group, and Cell type.

NOL4 PLPPR5 ZEB2

3.50e-041993138a04398653a1794921d73a6a950c1fb6fdf68c85
ToppCellFetal_brain-fetalBrain_Zhong_nature-GW16-Neuronal|GW16 / Sample Type, Dataset, Time_group, and Cell type.

DPYSL5 NOL4 ZEB2

3.55e-042003131decf1d2cba5ebfd3e5cd4bcd637db8f193033ce
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal-Cortical_neuron|GW16 / Sample Type, Dataset, Time_group, and Cell type.

DPYSL5 NOL4 ZEB2

3.55e-0420031319055194a5e0ea122f1b8fc62df44813f6843c95
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal|GW10 / Sample Type, Dataset, Time_group, and Cell type.

NOL4 TRAM1L1 ZEB2

3.55e-0420031304699d1149a143b96d6f292c0d70c4d3e6dfc611
Diseasebody mass index, fasting blood glucose measurement

DPYSL5 FADS2 MADD

2.11e-0551313EFO_0004340, EFO_0004465
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [1] measurement

FADS2 TM6SF2

4.78e-0510312EFO_0800507
Diseasephosphatidylcholine 34:4 measurement

FADS2 TM6SF2

7.00e-0512312EFO_0010378
Disease1-myristoyl-2-arachidonoyl-GPC (14:0/20:4) measurement

FADS2 TM6SF2

7.00e-0512312EFO_0800453
Diseaselinoleoyl-arachidonoyl-glycerol (18:2/20:4) [2] measurement

FADS2 TM6SF2

7.00e-0512312EFO_0800500
Diseaseoleoyl-arachidonoyl-glycerol (18:1/20:4) [2] measurement

FADS2 TM6SF2

1.11e-0415312EFO_0800508
Diseasesleep duration, triglyceride measurement

FADS2 MICAL3 TM6SF2

1.78e-04104313EFO_0004530, EFO_0005271
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

FADS2 TM6SF2

1.81e-0419312OBA_2045199
Diseasediacylglycerol 38:5 measurement

FADS2 TM6SF2

1.81e-0419312EFO_0020067
Diseaselevel of Phosphatidylcholine (18:1_20:4) in blood serum

FADS2 TM6SF2

2.22e-0421312OBA_2045104
Diseaselevel of Phosphatidylcholine (16:0_20:4) in blood serum

FADS2 TM6SF2

2.22e-0421312OBA_2045076
Diseaseproprotein convertase subtilisin/kexin type 9 measurement

FADS2 TM6SF2

2.44e-0422312EFO_0009312
Diseaselevel of Sterol ester (27:1/16:0) in blood serum

FADS2 TM6SF2

3.42e-0426312OBA_2045191
Diseaselevel of Phosphatidylcholine (17:0_20:4) in blood serum

FADS2 TM6SF2

3.42e-0426312OBA_2045087
Diseaseserum albumin measurement

FADS2 MICAL3 TM6SF2 PPP4R4 MADD

3.53e-04592315EFO_0004535
Diseasevery low density lipoprotein particle size measurement

MPP2 FADS2 TM6SF2

3.67e-04133313EFO_0008594
Diseasecholesterol:total lipids ratio, low density lipoprotein cholesterol measurement

FADS2 TM6SF2 MADD

4.63e-04144313EFO_0004611, EFO_0020943
Diseaselevel of Sterol ester (27:1/20:4) in blood serum

FADS2 TM6SF2

4.87e-0431312OBA_2045198
Diseaselow density lipoprotein cholesterol measurement, phospholipids:total lipids ratio

FADS2 TM6SF2 PPP4R4

5.52e-04153313EFO_0004611, EFO_0020946
Diseaselysophosphatidylcholine 20:3 measurement

FADS2 TM6SF2

8.13e-0440312EFO_0010362
Diseasecholesteryl esters to total lipids in small LDL percentage

FADS2 TM6SF2

8.96e-0442312EFO_0022255
Diseaseconcentration of large LDL particles measurement

FADS2 TM6SF2

9.83e-0444312EFO_0022160
Diseasealcohol use disorder (implicated_via_orthology)

FADS2 PIK3CB MADD

1.11e-03195313DOID:1574 (implicated_via_orthology)
Diseasetotal lipids in small LDL

FADS2 TM6SF2

1.12e-0347312EFO_0022168
Diseasefree cholesterol in small VLDL measurement

FADS2 TM6SF2

1.12e-0347312EFO_0022272
Diseasefree cholesterol in medium VLDL measurement

FADS2 TM6SF2

1.12e-0347312EFO_0022269
Diseaseschizophrenia, anorexia nervosa

MPP2 MRPS30

1.17e-0348312MONDO_0005090, MONDO_0005351
Diseasecholesterol in small LDL measurement

FADS2 TM6SF2

1.22e-0349312EFO_0022227
Diseaseomega-6:omega-3 polyunsaturated fatty acid ratio

FADS2 TM6SF2

1.27e-0350312EFO_0010732
Diseasefree cholesterol to total lipids in small HDL percentage

FADS2 MADD

1.32e-0351312EFO_0022285
Diseasetotal lipids in medium LDL

FADS2 TM6SF2

1.37e-0352312EFO_0022180
Diseasecholesterol to total lipids in large HDL percentage

FADS2 MADD

1.53e-0355312EFO_0022234
Diseasefree cholesterol to total lipids in very large HDL percentage

FADS2 MADD

1.53e-0355312EFO_0022288
Diseasetriglycerides in very large VLDL measurement

FADS2 TM6SF2

1.59e-0356312EFO_0022325
Diseasetriglycerides in large VLDL measurement

FADS2 TM6SF2

1.59e-0356312EFO_0022178
Diseasephospholipids:total lipids ratio

FADS2 TM6SF2 MADD

1.72e-03227313EFO_0020946
Diseasetriglycerides in VLDL measurement

FADS2 TM6SF2

1.76e-0359312EFO_0022326
Diseasecholesteryl esters to total lipids in large HDL percentage

FADS2 MADD

1.76e-0359312EFO_0022248
Diseasetriglycerides to total lipids in large HDL percentage

FADS2 MADD

1.82e-0360312EFO_0022330
Diseasefree cholesterol to total lipids in medium HDL percentage

FADS2 MADD

1.82e-0360312EFO_0022282
Diseasephospholipids in large VLDL measurement

FADS2 TM6SF2

1.94e-0362312EFO_0022169
Diseasetotal lipids in very large VLDL measurement

FADS2 TM6SF2

1.94e-0362312EFO_0022313
Diseasephospholipids in very large VLDL measurement

FADS2 TM6SF2

1.94e-0362312EFO_0022299
Diseasecholesteryl esters:total lipids ratio, high density lipoprotein cholesterol measurement

FADS2 TM6SF2 MADD

2.09e-03243313EFO_0004612, EFO_0020944

Protein segments in the cluster

PeptideGeneStartEntry
KNMPQMANFVYNMYM

AQR

1356

O60306
FLRYFFYKSMASMMV

ATP8B3

996

O60423
PAMRKMLNHLYFYIM

CPA6

221

Q8N4T0
EKMYLYMPKLLYFMM

SDR16C5

261

Q8N3Y7
YMPKLLYFMMFLKSF

SDR16C5

266

Q8N3Y7
PMYFQYQIIMTMIVH

FADS2

276

O95864
SMVMYLTQFYEMFKD

MICAL3

611

Q7RTP6
VMAFVAMIYPLEYMF

MADD

336

Q8WXG6
NSFKMFMAYKDLYMV

DPYS

156

Q14117
MAQKMSFGFYKYSNM

KIAA0930

226

Q6ICG6
QMVIMAGTVMLAYYF

PLPPR5

16

Q32ZL2
MGYFMIQTYIPCIMT

GABRA4

256

P48169
QNIQYYMMFEVMEPT

TUBGCP2

691

Q9BSJ2
WFMQQNVFVPMKYML

MPP2

56

Q14168
YMIISREMFNPMYAL

HUWE1

4066

Q7Z6Z7
KAQMMTYYTVRMFLD

EBLN1

231

P0CF75
YIPYKFMNRYNGAMM

DSEL

611

Q8IZU8
SFQMFMTYKDLYMLR

DPYSL5

156

Q9BPU6
EYMYQVMKFNKFSLP

MIOX

196

Q9UGB7
RILTKMQFMKYMVYP

MRPS30

81

Q9NP92
MQFMKYMVYPQTFAL

MRPS30

86

Q9NP92
NRMQYSMEYFQFMKK

USP9X

2001

Q93008
QIYYRFLQRMFTIMM

PPP4R4

521

Q6NUP7
YPMFNLLMDIDSYMF

PIK3CB

66

P42338
SMIDYNMPITMAYMK

NOL4

186

O94818
PMSVMLFMYYQIYKA

HTR7

251

P34969
RPHSMMTFQMKFFYI

TRAM1L1

156

Q8N609
YVTMIAKMTANMFYI

TRPM6

966

Q9BX84
VYMRNSKYPQDLVMM

FASLG

211

P48023
KILVMFYYLMMNSSK

ZMYND12

311

Q9H0C1
FIMFYSKNISLMMNF

TMC5

806

Q6UXY8
PVAYPKVQMLMYMFY

TM6SF2

261

Q9BZW4
KVQMLMYMFYVLPFC

TM6SF2

266

Q9BZW4
MSVLKAYYAMNMEPN

ZEB2

656

O60315