Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cyclosporin A binding	PPIAL4C PPIAL4H PPIAL4F PPIAL4E PPIAL4A PPIAL4G	1.29e-08	24	140	6	GO:0016018
GeneOntologyMolecularFunction	peptidyl-prolyl cis-trans isomerase activity	PPIAL4C PPIAL4H PPIAL4F PPIAL4E PPIAL4A PPIAL4G	1.32e-06	50	140	6	GO:0003755
GeneOntologyMolecularFunction	cis-trans isomerase activity	PPIAL4C PPIAL4H PPIAL4F PPIAL4E PPIAL4A PPIAL4G	1.87e-06	53	140	6	GO:0016859
GeneOntologyMolecularFunction	cell adhesion molecule binding	FLNB CDH26 TNC ANXA7 PKP4 ITGAM ITGAX NDRG1 EPHA2 TENM1 KIRREL1 MACF1 CTNNB1 DMD	8.31e-05	599	140	14	GO:0050839
GeneOntologyMolecularFunction	amide binding	PPIAL4C PPIAL4H GCDH ITGAM CERT1 PPIAL4F PPIAL4E PPIAL4A PPIAL4G	2.65e-04	299	140	9	GO:0033218
GeneOntologyMolecularFunction	ryanodine-sensitive calcium-release channel activity	RYR1 RYR3	2.90e-04	4	140	2	GO:0005219
GeneOntologyMolecularFunction	isomerase activity	PPIAL4C CYP2J2 PPIAL4H PPIAL4F PPIAL4E PPIAL4A PPIAL4G	4.17e-04	192	140	7	GO:0016853
GeneOntologyMolecularFunction	calcium-induced calcium release activity	RYR1 RYR3	7.19e-04	6	140	2	GO:0048763
GeneOntologyBiologicalProcess	protein peptidyl-prolyl isomerization	PPIAL4C PPIAL4H PPIAL4F PPIAL4E PPIAL4A PPIAL4G	2.03e-07	38	140	6	GO:0000413
GeneOntologyBiologicalProcess	peptidyl-proline modification	PPIAL4C PPIAL4H PPIAL4F PPIAL4E PPIAL4A PPIAL4G	1.73e-06	54	140	6	GO:0018208
Domain	Cyclophilin-type_PPIase_CS	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	9.58e-06	19	136	4	IPR020892
Domain	Cyclophilin-type_PPIase	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.46e-05	21	136	4	IPR024936
Domain	Pro_isomerase	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.78e-05	22	136	4	PF00160
Domain	Cyclophilin-type_PPIase_dom	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.78e-05	22	136	4	IPR002130
Domain	Cyclophilin-like_dom	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.78e-05	22	136	4	IPR029000
Domain	CSA_PPIASE_2	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.78e-05	22	136	4	PS50072
Domain	-	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.78e-05	22	136	4	2.40.100.10
Domain	CSA_PPIASE_1	PPIAL4C PPIAL4F PPIAL4A PPIAL4G	1.78e-05	22	136	4	PS00170
Domain	Pectin_lyase_fold/virulence	PKHD1L1 CEMIP SHCBP1	2.06e-05	8	136	3	IPR011050
Domain	Ryanodine_rcpt	RYR1 RYR3	1.57e-04	3	136	2	IPR003032
Domain	Ryanrecept_TM4-6	RYR1 RYR3	1.57e-04	3	136	2	IPR009460
Domain	RyR	RYR1 RYR3	1.57e-04	3	136	2	PF02026
Domain	RR_TM4-6	RYR1 RYR3	1.57e-04	3	136	2	PF06459
Domain	Ryan_recept	RYR1 RYR3	1.57e-04	3	136	2	IPR013333
Domain	Rossmann-like_a/b/a_fold	FNBP1 PAPSS1 YARS2 PCYT2	2.66e-04	43	136	4	IPR014729
Domain	-	FNBP1 PAPSS1 YARS2 PCYT2	2.66e-04	43	136	4	3.40.50.620
Domain	Ndr	NDRG3 NDRG1	3.13e-04	4	136	2	PF03096
Domain	G8_domain	PKHD1L1 CEMIP	3.13e-04	4	136	2	IPR019316
Domain	NDRG	NDRG3 NDRG1	3.13e-04	4	136	2	IPR004142
Domain	G8	PKHD1L1 CEMIP	3.13e-04	4	136	2	PS51484
Domain	G8	PKHD1L1 CEMIP	3.13e-04	4	136	2	SM01225
Domain	G8	PKHD1L1 CEMIP	3.13e-04	4	136	2	PF10162
Domain	ACTININ_2	FLNB MACF1 DMD	6.01e-04	23	136	3	PS00020
Domain	ACTININ_1	FLNB MACF1 DMD	6.01e-04	23	136	3	PS00019
Domain	Actinin_actin-bd_CS	FLNB MACF1 DMD	6.01e-04	23	136	3	IPR001589
Domain	RIH_assoc-dom	RYR1 RYR3	7.75e-04	6	136	2	IPR013662
Domain	Pectin_lyas_fold	CEMIP SHCBP1	7.75e-04	6	136	2	IPR012334
Domain	PbH1	PKHD1L1 SHCBP1	7.75e-04	6	136	2	SM00710
Domain	-	CEMIP SHCBP1	7.75e-04	6	136	2	2.160.20.10
Domain	Ins145_P3_rec	RYR1 RYR3	7.75e-04	6	136	2	PF08709
Domain	RIH_assoc	RYR1 RYR3	7.75e-04	6	136	2	PF08454
Domain	RIH_dom	RYR1 RYR3	7.75e-04	6	136	2	IPR000699
Domain	Ins145_P3_rcpt	RYR1 RYR3	7.75e-04	6	136	2	IPR014821
Domain	Ryanodine_recept-rel	RYR1 RYR3	7.75e-04	6	136	2	IPR015925
Domain	-	RYR1 RYR3	7.75e-04	6	136	2	1.25.10.30
Domain	RYDR_ITPR	RYR1 RYR3	7.75e-04	6	136	2	PF01365
Domain	PbH1	PKHD1L1 SHCBP1	7.75e-04	6	136	2	IPR006626
Domain	ARM-type_fold	TNPO2 PKP4 PSMD2 XPO1 CLHC1 ELMO1 RYR3 IQCB1 CTNNB1	8.55e-04	339	136	9	IPR016024
Domain	Myosin_TH1	MYO1A MYO1F	1.08e-03	7	136	2	PF06017
Domain	Myosin_TH1	MYO1A MYO1F	1.08e-03	7	136	2	IPR010926
Domain	TH1	MYO1A MYO1F	1.08e-03	7	136	2	PS51757
Domain	Spectrin_repeat	MCF2 MACF1 DMD	1.20e-03	29	136	3	IPR002017
Domain	Arm	TNPO2 PKP4 CTNNB1	1.46e-03	31	136	3	PF00514
Domain	SPEC	MCF2 MACF1 DMD	1.60e-03	32	136	3	SM00150
Domain	Spectrin/alpha-actinin	MCF2 MACF1 DMD	1.60e-03	32	136	3	IPR018159
Domain	Cadherin	CDH26 FREM3 FREM1 CELSR2 DSG4	1.72e-03	118	136	5	IPR002126
Domain	Calx_beta	FREM3 FREM1	1.83e-03	9	136	2	IPR003644
Domain	Calx-beta	FREM3 FREM1	1.83e-03	9	136	2	PF03160
Domain	MIR	RYR1 RYR3	2.28e-03	10	136	2	PF02815
Domain	MIR_motif	RYR1 RYR3	2.28e-03	10	136	2	IPR016093
Domain	MIR	RYR1 RYR3	2.28e-03	10	136	2	PS50919
Domain	MIR	RYR1 RYR3	2.28e-03	10	136	2	SM00472
Pubmed	Pro-prion, as a membrane adaptor protein for E3 ligase c-Cbl, facilitates the ubiquitination of IGF-1R, promoting melanoma metastasis.	CTDSPL2 ASH1L GCDH GIGYF1 XPO1 ERLEC1 DCAF5 CLHC1 YARS2 NEK1 SHCBP1 AMOTL1 CSTF1 PLEKHH2 PRRC2B DNAH11	2.31e-08	689	141	16	36543142
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	FNBP1 FLNB CDH26 VPS45 ANXA7 RALGAPB ASH1L RDH10 RNF213 RABGAP1 PFKFB1 SLC30A4 CERT1 DNAH14 ZNF461 SHISA9 NDRG1 TOX3 PANK4 SEL1L3 MACF1 CAP2	1.55e-07	1489	141	22	28611215
Pubmed	Qualitative and quantitative analyses of protein phosphorylation in naive and stimulated mouse synaptosomal preparations.	HSPA4L TNC PKP4 PSMD2 PRICKLE2 SYN2 MACF1 CTNNB1 ATP2B2 ADGRL3 CAP2	1.93e-07	347	141	11	17114649
Pubmed	TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.	FNBP1 RBM11 ABCA4 TTC28 TNC MUC16 NEB RYR1 KMT2D MED22 CEP295 DSG4 PRRC2B DNAH11	3.62e-07	638	141	14	31182584
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	FNBP1 TTC28 RALGAPB R3HDM2 DCAF5 LGI2 SEL1L3 MACF1 ADGRL3 PRRC2B LARGE1	9.30e-07	407	141	11	12693553
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	PKP4 RALGAPB ERICH5 CELSR2 CEP89 EPHA2 KIRREL1 MACF1 RELL1 CTNNB1 DMD	1.29e-06	421	141	11	36976175
Pubmed	Protein interaction network of the mammalian Hippo pathway reveals mechanisms of kinase-phosphatase interactions.	TTC28 PKP4 RALGAPB R3HDM2 GIGYF1 CEP89 AMOTL1 KIRREL1 CEP295 CTNNB1 HSPA4	2.25e-06	446	141	11	24255178
Pubmed	NDRG2 and PRA1 interact and synergistically inhibit T-cell factor/β-catenin signaling.	NDRG3 NDRG1 CTNNB1	2.26e-06	7	141	3	23068607
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TTC28 RBBP7 PKP4 ASH1L RNF213 GCDH GIGYF1 RSRC2 DCAF5 ZNF461 METTL13 BRPF1 PANK4 MACF1 CEP295 PRRC2B ALPL	3.03e-06	1116	141	17	31753913
Pubmed	Association of ITGAX and ITGAM gene polymorphisms with susceptibility to IgA nephropathy.	ITGAM ITGAX	1.63e-05	2	141	2	31227791
Pubmed	Malignant hyperthermia, environmental heat stress, and intracellular calcium dysregulation in a mouse model expressing the p.G2435R variant of RYR1.	RYR1 ALPL	1.63e-05	2	141	2	30236258
Pubmed	Dmdmdx/Largemyd: a new mouse model of neuromuscular diseases useful for studying physiopathological mechanisms and testing therapies.	DMD LARGE1	1.63e-05	2	141	2	23798567
Pubmed	Nucleocytoplasmic shuttling of the Duchenne muscular dystrophy gene product dystrophin Dp71d is dependent on the importin α/β and CRM1 nuclear transporters and microtubule motor dynein.	XPO1 DMD	1.63e-05	2	141	2	24486332
Pubmed	Cloning of human cDNAs for Apg-1 and Apg-2, members of the Hsp110 family, and chromosomal assignment of their genes.	HSPA4L HSPA4	1.63e-05	2	141	2	10524232
Pubmed	Quantitative T2 combined with texture analysis of nuclear magnetic resonance images identify different degrees of muscle involvement in three mouse models of muscle dystrophy: mdx, Largemyd and mdx/Largemyd.	DMD LARGE1	1.63e-05	2	141	2	25710816
Pubmed	Leukocyte integrins.	ITGAM ITGAX	1.63e-05	2	141	2	8573344
Pubmed	Contractile impairment and structural alterations of skeletal muscles from knockout mice lacking type 1 and type 3 ryanodine receptors.	RYR1 RYR3	1.63e-05	2	141	2	9489997
Pubmed	BCR activated CLL B cells use both CR3 (CD11b/CD18) and CR4 (CD11c/CD18) for adhesion while CR4 has a dominant role in migration towards SDF-1.	ITGAM ITGAX	1.63e-05	2	141	2	34283878
Pubmed	The block of ryanodine receptors selectively inhibits fetal myoblast differentiation.	RYR1 RYR3	1.63e-05	2	141	2	12640042
Pubmed	Possible involvement of ryanodine receptor-mediated intracellular calcium release in the effect of corticotropin-releasing factor on adrenocorticotropin secretion.	RYR1 RYR3	1.63e-05	2	141	2	14592949
Pubmed	Characterization of four novel CAG repeat-containing cDNAs.	R3HDM2 KMT2D	1.63e-05	2	141	2	8595911
Pubmed	Mechanical unloading reduces microtubule actin crosslinking factor 1 expression to inhibit β-catenin signaling and osteoblast proliferation.	MACF1 CTNNB1	1.63e-05	2	141	2	29219183
Pubmed	Morphological abnormalities of adrenal gland and hypertrophy of liver in mutant mice lacking ryanodine receptors.	RYR1 RYR3	1.63e-05	2	141	2	9799464
Pubmed	Expression and functional activity of ryanodine receptors (RyRs) during skeletal muscle development.	RYR1 RYR3	1.63e-05	2	141	2	17118445
Pubmed	Muscle satellite cells and impaired late stage regeneration in different murine models for muscular dystrophies.	DMD LARGE1	1.63e-05	2	141	2	31413358
Pubmed	RyR3 amplifies RyR1-mediated Ca(2+)-induced Ca(2+) release in neonatal mammalian skeletal muscle.	RYR1 RYR3	1.63e-05	2	141	2	11500519
Pubmed	Deletion of the complement phagocytic receptors CR3 and CR4 does not alter susceptibility to experimental cerebral malaria.	ITGAM ITGAX	1.63e-05	2	141	2	22882618
Pubmed	Integrin CD11c contributes to monocyte adhesion with CD11b in a differential manner and requires Src family kinase activity.	ITGAM ITGAX	1.63e-05	2	141	2	18541300
Pubmed	Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.	DMD ALPL	1.63e-05	2	141	2	19151073
Pubmed	Targeting Wnt/tenascin C-mediated cross talk between pancreatic cancer cells and stellate cells via activation of the metastasis suppressor NDRG1.	TNC NDRG1	1.63e-05	2	141	2	35065073
Pubmed	Principal mutation hotspot for central core disease and related myopathies in the C-terminal transmembrane region of the RYR1 gene.	RYR1 RYR3	1.63e-05	2	141	2	12565913
Pubmed	Functional and morphological features of skeletal muscle from mutant mice lacking both type 1 and type 3 ryanodine receptors.	RYR1 RYR3	1.63e-05	2	141	2	9192302
Pubmed	The NIMA-related kinase NEK1 cycles through the nucleus.	XPO1 NEK1	1.63e-05	2	141	2	19699716
Pubmed	Isolation and partial cloning of ryanodine-sensitive Ca2+ release channel protein isoforms from human myometrial smooth muscle.	RYR1 RYR3	1.63e-05	2	141	2	7556644
Pubmed	CD11c- and CD11b-expressing mouse leukocytes transport single Toxoplasma gondii tachyzoites to the brain.	ITGAM ITGAX	1.63e-05	2	141	2	16051744
Pubmed	Overexpressed LEF-1 proteins display different nuclear localization patterns of beta-catenin in normal versus tumor cells.	XPO1 CTNNB1	1.63e-05	2	141	2	16378739
Pubmed	Pharmacologic and functional characterization of malignant hyperthermia in the R163C RyR1 knock-in mouse.	RYR1 ALPL	1.63e-05	2	141	2	17122579
Pubmed	Mice expressing T4826I-RYR1 are viable but exhibit sex- and genotype-dependent susceptibility to malignant hyperthermia and muscle damage.	RYR1 ALPL	1.63e-05	2	141	2	22131268
Pubmed	Ryanodine receptors in muscarinic receptor-mediated bronchoconstriction.	RYR1 RYR3	1.63e-05	2	141	2	15894801
Pubmed	CD11c(+)/CD11b(+) cells are critical for organic dust-elicited murine lung inflammation.	ITGAM ITGAX	1.63e-05	2	141	2	22822029
Pubmed	Effect of calmodulin on Ca2+-induced Ca2+ release of skeletal muscle from mutant mice expressing either ryanodine receptor type 1 or type 3.	RYR1 RYR3	1.63e-05	2	141	2	9817784
Pubmed	KIAA1199 promotes migration and invasion by Wnt/β-catenin pathway and MMPs mediated EMT progression and serves as a poor prognosis marker in gastric cancer.	CEMIP CTNNB1	1.63e-05	2	141	2	28422983
Pubmed	Lethal multiple pterygium syndrome, large cystic hygroma, and cleft palate: Rare and severe fetal presentations of RYR1- and NEB-related congenital myopathies.	NEB RYR1	1.63e-05	2	141	2	38520674
Pubmed	Biallelic mutations in FLNB cause a skeletal dysplasia with 46,XY gonadal dysgenesis by activating β-catenin.	FLNB CTNNB1	1.63e-05	2	141	2	29095481
Pubmed	High NDRG3 expression facilitates HCC metastasis by promoting nuclear translocation of β-catenin.	NDRG3 CTNNB1	1.63e-05	2	141	2	31072445
Pubmed	Impaired OTUD7A-dependent Ankyrin regulation mediates neuronal dysfunction in mouse and human models of the 15q13.3 microdeletion syndrome.	VPS45 TNPO2 ELMO1 SHISA9 PRICKLE2 MACF1 ADGRL3	1.67e-05	197	141	7	36604605
Pubmed	Cooperative polarization of MCAM/CD146 and ERM family proteins in melanoma.	NIBAN1 PKP4 NDRG1 SLC12A4 EPHA2 KIRREL1 RELL1 CTNNB1 DMD	2.50e-05	377	141	9	38117590
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	CTDSPL2 PKP4 RALGAPB RNF213 PTPN23 PSMD2 XPO1 KMT2D SLC12A4 CEP89 KIRREL1 RELL1 DMD CAP2 PRRC2B	2.50e-05	1049	141	15	27880917
Pubmed	A high-throughput approach for measuring temporal changes in the interactome.	FLNB NIBAN1 HSPA4L RBBP7 PTPN23 PSMD2 RABGAP1 XPO1 PAPSS1 CERT1 NDRG1 PANK4 PCYT2 MACF1 HERC4 HSPA4 BAG6 CAP2	2.58e-05	1455	141	18	22863883
Pubmed	The TRIM9/TRIM67 neuronal interactome reveals novel activators of morphogenesis.	AGAP5 PKP4 R3HDM2 GIGYF1 SNCAIP MYO1F PRRC2B	3.21e-05	218	141	7	33378226
Pubmed	Identification of a novel cell-adhesive protein spatiotemporally expressed in the basement membrane of mouse developing hair follicle.	TNC FREM3 FREM1	3.51e-05	16	141	3	15878328
Pubmed	Disrupted in Schizophrenia 1 Interactome: evidence for the close connectivity of risk genes and a potential synaptic basis for schizophrenia.	MYT1L RABGAP1 MACF1 CEP295 DMD CCDC136	3.67e-05	151	141	6	17043677
Pubmed	RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly.	HSPA4L TNPO2 PSMD2 XPO1 HSPA4	3.78e-05	92	141	5	23055941
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	CYP2J2 NEB FREM1 MACF1 HSPA4 DNAH11	3.81e-05	152	141	6	34299191
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	MYT1L TTC28 RALGAPB PTPN23 HEPH METTL13 MACF1	3.92e-05	225	141	7	12168954
Pubmed	Investigation of genetic susceptibility factors for human longevity - a targeted nonsynonymous SNP study.	GALNT15 HSPA4L PSMD2 PRKAG3 NEK1 BAG6 KCNH5 LARGE1	4.42e-05	313	141	8	20800603
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	FLNB HSPA4L RBBP7 PTPN23 PSMD2 XPO1 ERLEC1 EPHA2 SHCBP1 CSTF1 DMD HSPA4 BAG6 PRRC2B	4.47e-05	974	141	14	28675297
Pubmed	Type 1 and type 3 ryanodine receptors are selectively involved in muscarinic antinociception in mice: an antisense study.	RYR1 RYR3	4.88e-05	3	141	2	18403125
Pubmed	Characterization and mapping of the 12 kDa FK506-binding protein (FKBP12)-binding site on different isoforms of the ryanodine receptor and of the inositol 1,4,5-trisphosphate receptor.	RYR1 RYR3	4.88e-05	3	141	2	11171121
Pubmed	Influence of microcurrent on the modulation of remodelling genes in a wound healing assay.	FMOD TNC	4.88e-05	3	141	2	33475929
Pubmed	Aggravated Lyme carditis in CD11a-/- and CD11c-/- mice.	ITGAM ITGAX	4.88e-05	3	141	2	16239568
Pubmed	Chromosomal location of the genes encoding the leukocyte adhesion receptors LFA-1, Mac-1 and p150,95. Identification of a gene cluster involved in cell adhesion.	ITGAM ITGAX	4.88e-05	3	141	2	3284962
Pubmed	The distinct leukocyte integrins of mouse spleen dendritic cells as identified with new hamster monoclonal antibodies.	ITGAM ITGAX	4.88e-05	3	141	2	2185332
Pubmed	The ryanodine receptor/calcium channel genes are widely and differentially expressed in murine brain and peripheral tissues.	RYR1 RYR3	4.88e-05	3	141	2	7876312
Pubmed	Socioeconomic status moderates associations between CNS serotonin and expression of beta2-integrins CD11b and CD11c.	ITGAM ITGAX	4.88e-05	3	141	2	19800635
Pubmed	Surfactant protein D regulates the cell surface expression of alveolar macrophage beta(2)-integrins.	ITGAM ITGAX	4.88e-05	3	141	2	17056703
Pubmed	Direct interaction of Alzheimer's disease-related presenilin 1 with armadillo protein p0071.	PKP4 CTNNB1	4.88e-05	3	141	2	10092585
Pubmed	Tenascin-C-EGFR activation induces functional human satellite cell proliferation and promotes wound-healing of skeletal muscles via oleanic acid.	TNC DMD	4.88e-05	3	141	2	37758009
Pubmed	Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin.	XPO1 CTNNB1	4.88e-05	3	141	2	14981260
Pubmed	Bidirectional coupling between ryanodine receptors and Ca2+ release-activated Ca2+ (CRAC) channel machinery sustains store-operated Ca2+ entry in human T lymphocytes.	RYR1 RYR3	4.88e-05	3	141	2	22948152
Pubmed	Congenital hearing impairment associated with peripheral cochlear nerve dysmyelination in glycosylation-deficient muscular dystrophy.	DMD LARGE1	4.88e-05	3	141	2	32453729
Pubmed	Developmental changes in expression of the three ryanodine receptor mRNAs in the mouse brain.	RYR1 RYR3	4.88e-05	3	141	2	10788707
Pubmed	Haplotype analysis of the CD11 gene cluster in patients with chronic Helicobacter pylori infection and gastric ulcer disease.	ITGAM ITGAX	4.88e-05	3	141	2	15730520
Pubmed	CEMIP, a novel adaptor protein of OGT, promotes colorectal cancer metastasis through glutamine metabolic reprogramming via reciprocal regulation of β-catenin.	CEMIP CTNNB1	4.88e-05	3	141	2	34608265
Pubmed	Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).	ITGAM ITGAX	4.88e-05	3	141	2	19129174
Pubmed	Association study of ITGAM, ITGAX, and CD58 autoimmune risk loci in systemic sclerosis: results from 2 large European Caucasian cohorts.	ITGAM ITGAX	4.88e-05	3	141	2	21362770
Pubmed	Ca(2+)-induced Ca2+ release in myocytes from dyspedic mice lacking the type-1 ryanodine receptor.	RYR1 RYR3	4.88e-05	3	141	2	7621815
Pubmed	N-myc downstream regulated gene 1 suppresses osteoblast differentiation through inactivating Wnt/β-catenin signaling.	NDRG1 CTNNB1	4.88e-05	3	141	2	35120575
Pubmed	Dysfunction of complement receptors CR3 (CD11b/18) and CR4 (CD11c/18) in pre-eclampsia: a genetic and functional study.	ITGAM ITGAX	4.88e-05	3	141	2	33539617
Pubmed	Multinucleated Giant Cells Are Specialized for Complement-Mediated Phagocytosis and Large Target Destruction.	ITGAM ITGAX	4.88e-05	3	141	2	26628365
Pubmed	Induction of murine macrophage TNF-alpha synthesis by Mycobacterium avium is modulated through complement-dependent interaction via complement receptors 3 and 4 in relation to M. avium glycopeptidolipid.	ITGAM ITGAX	4.88e-05	3	141	2	15899409
Pubmed	Molecular identification of the ryanodine receptor pore-forming segment.	RYR1 RYR3	4.88e-05	3	141	2	10473538
Pubmed	Differential alterations in expressions of ryanodine receptor subtypes in cerebellar cortical neurons of an ataxic mutant, rolling mouse Nagoya.	RYR1 RYR3	4.88e-05	3	141	2	18313230
Pubmed	Heterogeneous gene expression and functional activity of ryanodine receptors in resistance and conduit pulmonary as well as mesenteric artery smooth muscle cells.	RYR1 RYR3	4.88e-05	3	141	2	18434746
Pubmed	Lysine methyltransferase 2D regulates muscle fiber size and muscle cell differentiation.	KMT2D DMD	4.88e-05	3	141	2	34613626
Pubmed	Iron promotes oxidative cell death caused by bisretinoids of retina.	ABCA4 HEPH	4.88e-05	3	141	2	29686088
Pubmed	N-myc downstream-regulated gene 1 is mutated in hereditary motor and sensory neuropathy-Lom.	NDRG3 NDRG1	4.88e-05	3	141	2	10831399
Pubmed	SPRY domains in ryanodine receptors (Ca(2+)-release channels).	RYR1 RYR3	4.88e-05	3	141	2	9204703
Pubmed	Ryanodine receptors are expressed in epidermal keratinocytes and associated with keratinocyte differentiation and epidermal permeability barrier homeostasis.	RYR1 RYR3	4.88e-05	3	141	2	21881589
Pubmed	New insights into the genetic basis of premature ovarian insufficiency: Novel causative variants and candidate genes revealed by genomic sequencing.	XPO1 MACF1	4.88e-05	3	141	2	33036707
Pubmed	Isoform-dependent formation of heteromeric Ca2+ release channels (ryanodine receptors).	RYR1 RYR3	4.88e-05	3	141	2	12213830
Pubmed	CD11a regulates effector CD8 T cell differentiation and central memory development in response to infection with Listeria monocytogenes.	ITGAM ITGAX	4.88e-05	3	141	2	23357382
Pubmed	Expression of the ryanodine receptor type 3 calcium release channel during development and differentiation of mammalian skeletal muscle cells.	RYR1 RYR3	4.88e-05	3	141	2	9242641
Pubmed	[Participation of beta2-integrins CD11b/CD18 and CD11c/CD18 in adhesion and migration of cells on fibrinogen].	ITGAM ITGAX	4.88e-05	3	141	2	21874872
Pubmed	Claudin-4 controls the receptor tyrosine kinase EphA2 pro-oncogenic switch through β-catenin.	EPHA2 CTNNB1	4.88e-05	3	141	2	25344320
Pubmed	CR3 (CD11b/CD18) and CR4 (CD11c/CD18) are involved in complement-independent antibody-mediated phagocytosis of Cryptococcus neoformans.	ITGAM ITGAX	4.88e-05	3	141	2	12121661
Pubmed	Infiltrating CD11b+CD11c+ cells have the potential to mediate inducible nitric oxide synthase-dependent cell death in mammary carcinomas of HER-2/neu transgenic mice.	ITGAM ITGAX	4.88e-05	3	141	2	19653277
Pubmed	Calcineurin upregulates local Ca(2+) signaling through ryanodine receptor-1 in airway smooth muscle cells.	RYR1 RYR3	4.88e-05	3	141	2	25239916
Pubmed	A gene-specific cerebral types 1, 2, and 3 RyR protein knockdown induces an antidepressant-like effect in mice.	RYR1 RYR3	4.88e-05	3	141	2	18643873
Pubmed	The metastasis suppressor, NDRG1, inhibits "stemness" of colorectal cancer via down-regulation of nuclear β-catenin and CD44.	NDRG1 CTNNB1	4.88e-05	3	141	2	26418878
Interaction	PRNP interactions	CTDSPL2 HSPA4L TNC ANXA7 ASH1L PSMD2 GCDH GIGYF1 XPO1 ERLEC1 DCAF5 CLHC1 YARS2 NEK1 SHCBP1 AMOTL1 CSTF1 SYN2 MACF1 DMD PLEKHH2 ATP2B2 HSPA4 BAG6 PRRC2B DNAH11	8.53e-08	1158	139	26	int:PRNP
Interaction	DIRAS3 interactions	RBM11 VPS45 PKP4 PSMD2 SLC12A4 CEP89 EPHA2 MAP3K9 KIRREL1 MACF1 RELL1	2.09e-06	262	139	11	int:DIRAS3
Cytoband	1q21.2	PPIAL4C VPS45 PPIAL4F PPIAL4E	7.06e-05	71	141	4	1q21.2
Cytoband	12q13-q14	MYO1A BLOC1S1	1.39e-04	6	141	2	12q13-q14
GeneFamily	Ryanodine receptors\|Protein phosphatase 1 regulatory subunits	RYR1 RYR3	7.17e-05	3	89	2	287
GeneFamily	Myosins, class I	MYO1A MYO1F	6.58e-04	8	89	2	1097
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 NEB PKHD1L1 FREM1 RYR3 TENM1 DMD ADGRL3 DNAH11	7.27e-09	184	140	9	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 NEB PKHD1L1 FREM1 RYR3 TENM1 DMD ADGRL3 DNAH11	7.27e-09	184	140	9	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 NEB PKHD1L1 FREM1 RYR3 TENM1 DMD ADGRL3 DNAH11	7.27e-09	184	140	9	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	FNBP1 FLNB NIBAN1 TNC RYR3 MACF1 DMD ADGRL3	1.49e-07	188	140	8	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FNBP1 FLNB TNC RYR3 ARHGEF10L MACF1 DMD ADGRL3	1.56e-07	189	140	8	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	Adult-Immune-interstitial_macrophage_(C1Q_positive)\|Adult / Lineage, Cell type, age group and donor	FNBP1 ITGAM ELMO1 CD163 RYR1 ARHGEF10L LGI2 MYO1F	1.83e-07	193	140	8	31c0978ba78c9516d498aec0798902e57555e557
ToppCell	TCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma-4\|TCGA-Prostate / Sample_Type by Project: Shred V9	HEPH STAT5A ANKRD53 SNCAIP SLC12A4 EPHA2 KIRREL1 PLEKHH2	1.98e-07	195	140	8	5562665dd3beb70e2358aa32611a337bef5731c1
ToppCell	18-Distal-Epithelial-Basal_cell\|Distal / Age, Tissue, Lineage and Cell class	RBM11 CDH26 CYP2J2 LRRC9 CEMIP CEP295 ALPL	7.00e-07	158	140	7	183f445967e09e871c93d8e94781ed9fec894169
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CDH26 RDH10 MUC16 SHISA9 EPHA2 TOX3 SEL1L3	7.94e-07	161	140	7	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 MYO1A ITGAM ITGAX ELMO1 CD163 MYO1F	1.24e-06	172	140	7	f6b4754a7e4b3e38030316a0ae00d932bfa87e41
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SHISA9 LGI2 SEL1L3 PLEKHH2 ADGRL3 DNAH11 LARGE1	1.44e-06	176	140	7	327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCell	5'-Adult-Appendix-Mesenchymal-myocytic-myofibroblast\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TMEM67 TTC28 ADAMTS3 PRICKLE2 TENM1 DMD PLEKHH2	1.50e-06	177	140	7	e65c0568dc5852108e9802273499bc7cf88fafab
ToppCell	FF-Differ-KC\|World / shred by cell class for mouse tongue	RGSL1 RYR1 SNCAIP DSG4 EML1 ALPL DNAH11	1.61e-06	179	140	7	1526a130565a97c291a25a7a988089bffc1515c1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHISA9 LGI2 SEL1L3 KIRREL1 PLEKHH2 ADGRL3 DNAH11	1.74e-06	181	140	7	6a6bd8e020cb0929b6ecdcb55d467ad24fecfaf0
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 SHISA9 LGI2 SEL1L3 PLEKHH2 DNAH11 LARGE1	1.80e-06	182	140	7	5e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB CDH26 CYP2J2 MUC16 SHISA9 TOX3 SEL1L3	1.80e-06	182	140	7	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F CCDC136	1.87e-06	183	140	7	a97f052950429245c3231464271e1ba539863bba
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	FNBP1 FLNB NIBAN1 TNC LGI2 DMD ADGRL3	1.87e-06	183	140	7	818fd886e0188091310825f9145fa53328f2c979
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 LGI2 SEL1L3 PLEKHH2 ADGRL3 DNAH11 LARGE1	2.08e-06	186	140	7	5c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH14 SHISA9 KIRREL1 PLEKHH2 ADGRL3 DNAH11 LARGE1	2.24e-06	188	140	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH14 SHISA9 LGI2 SEL1L3 PLEKHH2 ADGRL3 DNAH11	2.32e-06	189	140	7	904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Ascending_Vasa_Recta_Endothelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT15 PKHD1L1 ELMO1 RYR3 SNCAIP GBP4 EML1	2.40e-06	190	140	7	656483751e4bf137e4e4bfb2a03a478a8f7fcb63
ToppCell	Children_(3_yrs)-Epithelial-club_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NIBAN1 CDH26 CYP2J2 EPHA2 TOX3 SEL1L3 PRICKLE2	2.48e-06	191	140	7	23776c7302cead3881b39127398f3b3e0d27885e
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	GALNT15 PKHD1L1 ELMO1 RYR3 SNCAIP GBP4 EML1	2.66e-06	193	140	7	287e756d5fd3bd2931c168da24beaa0d02a350ae
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	2.75e-06	194	140	7	96f16bcd393a0d3f8df479b172b5360ae5a1e663
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYT1L NIBAN1 MUC16 DNAH14 RYR3 PRKAG3 ALPL	2.85e-06	195	140	7	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	MYT1L NIBAN1 MUC16 DNAH14 RYR3 PRKAG3 ALPL	2.85e-06	195	140	7	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	Secretory\|World / shred by cell class for bronchial biopsy	SQLE RDH10 MUC16 PSMD2 MED22 SEL1L3 ALPL	2.85e-06	195	140	7	52f8281fe0df67cec3faa780a23ed6343ed5a6ba
ToppCell	facs-Skin-Telogen-3m-Epithelial-bulge_keratinocyte\|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNB HSPA4L TNC NDRG1 MACF1 CTNNB1 DMD	2.95e-06	196	140	7	90edf61116ffcb4f8b6be3d0a05732d59b0a87d5
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	TNC RDH10 RYR3 CEMIP CELSR2 TENM1 EML1	2.95e-06	196	140	7	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 NIBAN1 ITGAM ITGAX ELMO1 CD163 MYO1F	3.05e-06	197	140	7	61ef3f417767c3f5296a26399da63e3e4f58faf8
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.15e-06	198	140	7	96883ad8e189a46ed5b7eaafc0543e53682d26ed
ToppCell	Parenchymal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	FLNB NIBAN1 CDH26 CYP2J2 PKP4 TOX3 SEL1L3	3.15e-06	198	140	7	af399569c718f5fd971d73a7926768c9311002a3
ToppCell	Fetal_29-31_weeks-Epithelial-club_cell-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	NIBAN1 CDH26 CYP2J2 MYRFL NDRG1 TOX3 SEL1L3	3.15e-06	198	140	7	6ba5e5970109a04ed968bac7ff099ae250c579dc
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	FLNB PKP4 ASH1L RNF213 TOX3 MACF1 ADGRL3	3.37e-06	200	140	7	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-TAM-BDM-TAM-BDM_hypoxia/MES-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	FLNB ITGAM ITGAX CD163 STAT5A NDRG1 MYO1F	3.37e-06	200	140	7	851c57187db8bc91a393655bca5f13e787a723d4
ToppCell	TCGA-Bone_and_Soft_Tissue-Primary_Tumor-Sarcoma-Conventional_Leiomyosarcoma\|TCGA-Bone_and_Soft_Tissue / Sample_Type by Project: Shred V9	FNBP1 RABGAP1 RYR3 CELSR2 DMD CAP2	9.04e-06	153	140	6	ec6fe6b8c884fa76adc7a0f9db041f7b1567a2ee
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA4 FREM3 ITGAM TENM1 MAP3K9 ALPL	9.38e-06	154	140	6	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ABCA4 FREM3 ITGAM TENM1 MAP3K9 ALPL	9.38e-06	154	140	6	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	AK9 SLC30A4 RYR3 AMOTL1 CCDC136 GABRA5	9.38e-06	154	140	6	16fdafb5c64d2db321554f87129a962d113f1668
ToppCell	VE-CD8-naive_CD4\|VE / Condition, Cell_class and T cell subcluster	AGAP5 AMY2B PKP4 DNAH14 ZNF461 PLEKHH2	1.17e-05	160	140	6	255d2a150bfe19ee3d4d34533feb9c37ce73d225
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CYP2J2 PAPSS1 SLC30A4 DNAH14 CEP89 MAP3K9	1.21e-05	161	140	6	7c9d4410d7142a5f3a05418c994f69978c9ffa17
ToppCell	droplet-Limb_Muscle-nan-18m-Myeloid-chondrocyte-like\|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TNC ITGAM CD163 ARHGEF10L CEMIP MYO1F	1.25e-05	162	140	6	71d7849108a1b59beff40e46000172c45a2f5439
ToppCell	facs-Lung-EPCAM-18m-Myeloid-non-classical_monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAM CLHC1 ARHGEF10L BRPF1 MYO1F HERC4	1.25e-05	162	140	6	484ea4ac40de672dcbd2583a52cb7f385c918814
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Nonclassical_Monocyte\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ITGAM CLHC1 ARHGEF10L BRPF1 MYO1F HERC4	1.25e-05	162	140	6	bba144ac5332bab9eba2ccf599703c781a7f88f1
ToppCell	COVID-19-kidney-Technical/muscle_(Imm)\|kidney / Disease (COVID-19 only), tissue and cell type	MYT1L RYR1 MYO1F DMD ADGRL3 KCNH5	1.30e-05	163	140	6	19c28ce16a588a7f4a035c32726f6ccd67702b5b
ToppCell	facs-MAT-Fat-3m-Myeloid-nan\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNBP1 ITGAM ITGAX CD163 RYR1 MYO1F	1.34e-05	164	140	6	1250876abd7311f86730e5b9c03c3610cc2ff6d3
ToppCell	facs-MAT-Fat-3m-Myeloid\|MAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNBP1 ITGAM ITGAX CD163 RYR1 MYO1F	1.34e-05	164	140	6	fa0d77b648cde5e42b9394e877168c80de238bde
ToppCell	facs-Lung-EPCAM-3m-Myeloid-Myeloid_Dendritic_Type_1\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNBP1 NIBAN1 ITGAX CD163 RYR1 MYO1F	1.39e-05	165	140	6	2477b0f1a0ea26184cf3cc4a9ffcdfa825cbc615
ToppCell	facs-Diaphragm-Limb_Muscle-24m\|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYT1L PKHD1L1 RYR3 TRPM8 ATP2B2 DNAH11	1.59e-05	169	140	6	12bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ARHGEF10L SHISA9 LGI2 SEL1L3 DNAH11	1.64e-05	170	140	6	5d5f208682be21ed58320f5fc083a7898f8712da
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-Pericyte_3\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	NIBAN1 FREM1 ARHGEF10L LGI2 DMD CAP2	1.70e-05	171	140	6	4ede831aed364cb5271f49a8b09bb6d0452f9b35
ToppCell	FLU-Healthy-3\|FLU / Virus stimulation, Condition and Cluster	AMY2B ITGAX YARS2 SHCBP1 CCDC136 OPLAH	1.82e-05	173	140	6	32b8e5b400885dbeba57a7cb2c18d882664dc285
ToppCell	FLU-Healthy-3\|Healthy / Virus stimulation, Condition and Cluster	AMY2B ITGAX YARS2 SHCBP1 CCDC136 OPLAH	1.82e-05	173	140	6	26e89ac86922f1cd0100cf4d1cce37e74dd31c88
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB CDH26 CYP2J2 MUC16 SHISA9 TOX3	1.82e-05	173	140	6	464267a2ff3f5c387b6c9c6fa4dab135a221f448
ToppCell	Thalamus-Neuronal-Excitatory\|Thalamus / BrainAtlas - Mouse McCarroll V32	MYT1L NDRG3 AMOTL1 SEL1L3 CCDC136 KCNH5	2.00e-05	176	140	6	d2bbf13d21fb7582d7e5f90cd61a4ebe1cfccd66
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGAM ITGAX CD163 ARHGEF10L MYO1F CD180	2.07e-05	177	140	6	cdad5a2f672a7f07c05669bfcaf1ec74defd3de7
ToppCell	LPS-IL1RA+antiTNF-Myeloid-Monocytes,_Macrophages-Monocytes-Macrophages\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ITGAM ITGAX CD163 ARHGEF10L MYO1F CD180	2.07e-05	177	140	6	991ae76bb615392d84aeb89886148fa42c1c649c
ToppCell	facs-Lung-EPCAM-3m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FNBP1 NIBAN1 ITGAX CD163 RYR1 MYO1F	2.07e-05	177	140	6	e73e2b6a72630bb56ac2af1cdeedc8f0f828f390
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 KIRREL1 DMD ADGRL3 DNAH11 LARGE1	2.07e-05	177	140	6	a8625d14682183cf77cb51eaf11bc15a3528f586
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 KIRREL1 DMD ADGRL3 DNAH11 LARGE1	2.07e-05	177	140	6	3645e2f4a48283f290f85c49c3e79e3f58ac9aa6
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ELMO1 CD163 RYR1 MYO1F CCDC136	2.13e-05	178	140	6	24e8c62060455159235985f456af0c5023a7f3f5
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Macrophage_Dendritic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ELMO1 CD163 RYR1 MYO1F CCDC136	2.13e-05	178	140	6	4f1cc954d4d9b5b2b75a4cf995ba81e2ada27084
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGAM ITGAX CD163 RYR1 MYO1F CD180	2.20e-05	179	140	6	716856b2c7c660bf5ce00e63efeda6ed121f2baa
ToppCell	5'-Adult-Appendix-Hematopoietic-Myeloid-LYVE1+_Macrophage\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	2.27e-05	180	140	6	66c7b02d85e32ba3e7530d0c4aff17e7525ccdd8
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial-Mesothelial_mature\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT15 FMOD MUC16 PKHD1L1 SYN2 KIRREL1	2.34e-05	181	140	6	330d4322f4c4373f706273c1f4e218b59051b7fd
ToppCell	3'-GW_trimst-1.5-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ITGAM ITGAX CD163 RYR1 MYO1F CD180	2.34e-05	181	140	6	090e89b506d945e123e647d08947e9649a65ce7c
ToppCell	PND28-Mesenchymal-Mesenchymal_structural-Fibroblastic-Mesothelial\|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GALNT15 FMOD MUC16 PKHD1L1 SYN2 KIRREL1	2.34e-05	181	140	6	3f4d5d79c1286614514b0e8134079d6128a2a23e
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	FLNB CDH26 CYP2J2 EPHA2 TOX3 SEL1L3	2.42e-05	182	140	6	215c303df42f13597b2c7a95cb157c6bc7aca9a1
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SHISA9 SEL1L3 KIRREL1 PLEKHH2 ADGRL3 DNAH11	2.49e-05	183	140	6	cfae90c309622b5d499e62a3a8a8b9746478d28d
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 ARHGEF10L SHISA9 LGI2 SEL1L3 ADGRL3	2.49e-05	183	140	6	92fbd83a9d13ee91065cbd479fb298f1fd564568
ToppCell	RA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	FNBP1 FLNB NIBAN1 TNC LGI2 DMD	2.49e-05	183	140	6	cae2ee08f985a6f005b4b8e959e465350315156a
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ADAMTS3 FREM1 ARHGEF10L NDRG1 SHCBP1 TOX3	2.81e-05	187	140	6	f6217d0dd425eac76900b44a4e48f45475f3ac36
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ABCA4 MYRFL ARHGEF10L SHISA9 LGI2 SEL1L3	2.81e-05	187	140	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	Mesenchymal_cells-Ng2+_MSCs\|Mesenchymal_cells / Lineage and Cell class	TNC CD163 GBP4 SHCBP1 CTNNB1 ALPL	2.81e-05	187	140	6	e899b906409f3fad69cb3d3c6432c3fd862ae3c1
ToppCell	renal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid-Macrophage_Dendritic-Cycling_Mononuclear_Phagocyte\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ELMO1 CD163 RYR1 SHCBP1 MYO1F	2.81e-05	187	140	6	73931a5ea73799095daff100b5f18853c57c74dc
ToppCell	Control-Endothelial-VE_Peribronchial\|Endothelial / Disease state, Lineage and Cell class	GALNT15 CDH26 ADAMTS3 TNC PKP4 RELL1	2.81e-05	187	140	6	5429ae85942b8ec3895cceb63c663de3c24ca064
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic-Monocyte-derived_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ITGAM ITGAX ELMO1 CD163 MYO1F	2.90e-05	188	140	6	0d7296ad26e97ad91c6927a6cfe4e6e70a74c5a6
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PKP4 MYRFL DNAH14 SHISA9 KIRREL1 PLEKHH2	3.08e-05	190	140	6	3fc9e18c7441c0ae8cda65753cc42d0520f4e116
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid-Monocytic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ITGAM ITGAX ELMO1 CD163 MYO1F	3.08e-05	190	140	6	7c402aa47f1bd7decacc366c1ed1a37e39b95c73
ToppCell	PND10\|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	NIBAN1 TNC AMOTL1 MACF1 CTNNB1 ADGRL3	3.08e-05	190	140	6	d67e2814047c8df2ae4b7bc8be9539f5df6ecef2
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	DNAH14 SHISA9 LGI2 SEL1L3 PLEKHH2 ADGRL3	3.17e-05	191	140	6	d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.26e-05	192	140	6	86d792682ba51696f503c79625dd20f87bcf651f
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid-Macrophage_Dendritic-M2_Macrophage\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.26e-05	192	140	6	d0ad6a205ad50a3c523fa68676996b289eabc5de
ToppCell	TCGA-Stomach-Primary_Tumor-Stomach_Adenocarcinoma-Stomach_Adenocarcinoma_-_NOS-6\|TCGA-Stomach / Sample_Type by Project: Shred V9	PKP4 RNF213 PSMD2 GBP4 EPHA2 SHCBP1	3.26e-05	192	140	6	4e689bca7a242f8482e25f273656e2caba8821c0
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_2-Alveolar_fibroblasts-Alveolar_fibroblasts_L.2.1.4.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	FMOD TNC NEB HEPH CEMIP HHIPL2	3.36e-05	193	140	6	5bee7abc550ddaa28cbb3b9ecaf6b924ab175de0
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.36e-05	193	140	6	f597fefc54327a1ad136e2f66b6e81cc5c761eb7
ToppCell	Bronchial-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH26 CYP2J2 RDH10 MUC16 SHISA9 TOX3	3.46e-05	194	140	6	e0228f593c3493175962a4817500d4337ddc4e88
ToppCell	Goblet\|World / shred by cell class for turbinate	NIBAN1 CYP2J2 RDH10 ERLEC1 SEL1L3 ALPL	3.46e-05	194	140	6	03b62e7cff5e7a6e7bd7d9dda273c74bf9c1f42e
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	TTC28 FREM1 ELMO1 PRICKLE2 MACF1 PLEKHH2	3.46e-05	194	140	6	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.46e-05	194	140	6	0866ab6792cee274a71991d5c37a37f574ff446e
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	MYRFL LGI2 AMOTL1 TOX3 TENM1 KIRREL1	3.46e-05	194	140	6	02a9cc821c2b14aa7d0e55661a5fab66364474e1
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Immune-Myeloid\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.56e-05	195	140	6	91a3c439f10c03c5d51d904f512b6a08040edc76
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	NIBAN1 ITGAM ITGAX ELMO1 CD163 MYO1F	3.56e-05	195	140	6	2d485373bfd9bb4bb9236bf0b31d03e132c8018f
ToppCell	Children_(3_yrs)-Epithelial-club_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	NIBAN1 CDH26 EPHA2 TOX3 SEL1L3 PRICKLE2	3.56e-05	195	140	6	dccc32fcf772e2504de7f663ef0a5bd8e23e92fc
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.56e-05	195	140	6	ce8215d503cad3a9bc7d5d2be4adb57408015593
ToppCell	renal_cortex_nuclei-Adult_normal_reference-Immune\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	FNBP1 NIBAN1 ITGAX ELMO1 CD163 MYO1F	3.56e-05	195	140	6	7b6c69df943842b566a596e30bb50dbe80dccc83
ToppCell	renal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Immune-Myeloid\|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.56e-05	195	140	6	09df40ff9b493170861b3f6e57a942a834655b5c
ToppCell	Tracheal-NucSeq-Epithelial-Epi_airway_secretory\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CDH26 RDH10 MUC16 SHISA9 CAP2 ALPL	3.66e-05	196	140	6	b07db4a53ab9be9aad6fae5e45f9547db829d096
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ITGAM ITGAX ELMO1 CD163 RYR1 MYO1F	3.66e-05	196	140	6	4370473693d2dd4a8c451a4c477eb79baa33ae12
Drug	mono-(2-ethylhexyl)phthalate	ABCA4 RBBP7 SQLE NEB DNAH14 CD163 RYR1 ZNF461 PRKAG3 NEK1 NDRG1 CELSR2 TOX3 CTNNB1 DMD ALPL	2.07e-06	658	136	16	ctd:C016599
Drug	MBED	RYR1 RYR3 HSPA4	4.12e-06	6	136	3	CID000129958
Disease	Malignant neoplasm of liver	ANXA7 ASH1L NDRG1 TOX3 PRICKLE2 CTNNB1 LARGE1	3.68e-06	142	132	7	C0345904
Disease	Liver neoplasms	ANXA7 ASH1L NDRG1 TOX3 PRICKLE2 CTNNB1 LARGE1	3.68e-06	142	132	7	C0023903
Disease	congenital myopathy 1A (implicated_via_orthology)	RYR1 RYR3	5.94e-05	3	132	2	DOID:3529 (implicated_via_orthology)
Disease	malignant hyperthermia (implicated_via_orthology)	RYR1 RYR3	5.94e-05	3	132	2	DOID:8545 (implicated_via_orthology)
Disease	Cecal Neoplasms	KRT20 CTNNB1	1.18e-04	4	132	2	C0007528
Disease	Malignant neoplasm of cecum	KRT20 CTNNB1	1.18e-04	4	132	2	C0153437
Disease	Familial Exudative Vitreoretinopathy	ABCA4 CTNNB1	1.97e-04	5	132	2	C0339539
Disease	cholesterol:total lipids ratio, intermediate density lipoprotein measurement	R3HDM2 CERT1 PRKAG3 CELSR2 MACF1	2.18e-04	121	132	5	EFO_0008595, EFO_0020943
Disease	nephronophthisis (is_implicated_in)	TMEM67 IQCB1	2.94e-04	6	132	2	DOID:12712 (is_implicated_in)
Disease	MULTIPLE PTERYGIUM SYNDROME, LETHAL TYPE	NEB RYR1	2.94e-04	6	132	2	C1854678
Disease	phosphate measurement	RYR3 ALPL	4.11e-04	7	132	2	EFO_0010968
Disease	invasive lobular carcinoma (is_marker_for)	STAT5A CTNNB1	4.11e-04	7	132	2	DOID:3457 (is_marker_for)
Disease	triglycerides:total lipids ratio, very low density lipoprotein cholesterol measurement	ITGAM CERT1 PRKAG3 SLC12A4 CELSR2 MACF1	5.42e-04	225	132	6	EFO_0008317, EFO_0020947
Disease	Posterior subcapsular cataract	EPHA2 PANK4	5.46e-04	8	132	2	C0858617
Disease	post-operative acute kidney injury	CDH26 ARHGEF10L	7.00e-04	9	132	2	EFO_0009955
Disease	very low density lipoprotein cholesterol measurement, free cholesterol:total lipids ratio	ITGAM CERT1 PRKAG3 SLC12A4 CELSR2 MACF1	7.43e-04	239	132	6	EFO_0008317, EFO_0020945
Disease	Neurodevelopmental Disorders	MYT1L ASH1L CERT1 CTNNB1	8.21e-04	93	132	4	C1535926
Disease	low density lipoprotein cholesterol measurement, alcohol consumption measurement	CERT1 CELSR2 SYN2 DNAH11	1.04e-03	99	132	4	EFO_0004611, EFO_0007878
Disease	gastric adenocarcinoma (is_implicated_in)	XPO1 KMT2D	1.06e-03	11	132	2	DOID:3717 (is_implicated_in)
Disease	Gastric Adenocarcinoma	EPHA2 MAP3K9 CTNNB1	1.08e-03	45	132	3	C0278701
Disease	very low density lipoprotein cholesterol measurement	R3HDM2 CERT1 PRKAG3 CELSR2 MYO1F DNAH11	1.15e-03	260	132	6	EFO_0008317
Disease	low density lipoprotein cholesterol measurement, alcohol drinking	CERT1 CELSR2 SYN2 DNAH11	1.16e-03	102	132	4	EFO_0004329, EFO_0004611
Disease	Congenital muscular dystrophy	RYR1 LARGE1	1.27e-03	12	132	2	cv:C0699743
Disease	Congenital myopathy (disorder)	NEB RYR1	1.27e-03	12	132	2	C0270960
Disease	Ciliopathies	TMEM67 NEK1 IQCB1 DNAH11	1.53e-03	110	132	4	C4277690
Disease	esterified cholesterol measurement, low density lipoprotein cholesterol measurement	ADAMTS3 CELSR2	1.74e-03	14	132	2	EFO_0004611, EFO_0008589
Disease	parental longevity	MYT1L GALNT15 MAN2A2 ADAMTS3 RYR3 CEMIP CELSR2 PRICKLE2	1.76e-03	494	132	8	EFO_0007796
Disease	urate measurement, bone density	FNBP1 TTC28 DNAH14 FREM1 GBP4 ATP2B2 PRRC2B KCNH5 DNAH11	1.92e-03	619	132	9	EFO_0003923, EFO_0004531
Disease	autosomal recessive polycystic kidney disease (implicated_via_orthology)	TMEM67 NEK1	2.29e-03	16	132	2	DOID:0110861 (implicated_via_orthology)
Disease	fatty liver disease (is_marker_for)	CD163 ALPL	2.58e-03	17	132	2	DOID:9452 (is_marker_for)
Disease	triglycerides:total lipids ratio, intermediate density lipoprotein measurement	R3HDM2 PRKAG3 CELSR2 MACF1	2.59e-03	127	132	4	EFO_0008595, EFO_0020947
Disease	neuroticism measurement	MYT1L PKP4 RSRC2 DCAF5 ARHGEF10L SHISA9 MED22 TOX3 SYN2 BAG6 LARGE1	2.63e-03	909	132	11	EFO_0007660
Disease	triglycerides to total lipids in IDL percentage	CERT1 PRKAG3 CELSR2	2.86e-03	63	132	3	EFO_0022329
Disease	free cholesterol measurement, very low density lipoprotein cholesterol measurement	R3HDM2 CERT1 PRKAG3 CELSR2 DNAH11	2.87e-03	215	132	5	EFO_0008317, EFO_0008591
Disease	Headache	RNF213 MACF1 TRPM8	2.99e-03	64	132	3	HP_0002315
Disease	Seizures	SYN2 PCYT2 MACF1 ALPL GABRA5	3.04e-03	218	132	5	C0036572
Disease	very low density lipoprotein cholesterol measurement, lipid measurement	R3HDM2 CERT1 PRKAG3 CELSR2 DNAH11	3.17e-03	220	132	5	EFO_0004529, EFO_0008317
Disease	inosine measurement	DMD KCNH5	3.23e-03	19	132	2	EFO_0010503
Disease	level of Sphingomyelin (d38:2) in blood serum	ADAMTS3 MYO1F	3.23e-03	19	132	2	OBA_2045179
Disease	hydrocephalus (implicated_via_orthology)	TMEM67 CELSR2	3.23e-03	19	132	2	DOID:10908 (implicated_via_orthology)
Disease	low density lipoprotein cholesterol measurement, physical activity	CERT1 CELSR2 DNAH11	3.26e-03	66	132	3	EFO_0003940, EFO_0004611
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	ITGAM CERT1 PRKAG3 CELSR2 MACF1	3.29e-03	222	132	5	EFO_0008317, EFO_0020943
Disease	common carotid intimal medial thickness	RGSL1 RYR3 CD180	3.40e-03	67	132	3	EFO_0004860
Disease	cholesterol to total lipids in very small VLDL percentage	CERT1 PRKAG3 CELSR2	3.40e-03	67	132	3	EFO_0022245
Disease	triglyceride measurement, very low density lipoprotein cholesterol measurement	R3HDM2 CERT1 PRKAG3 CELSR2 MACF1	3.42e-03	224	132	5	EFO_0004530, EFO_0008317
Disease	fatty acid measurement	ABCA4 R3HDM2 CERT1 PRKAG3 SHISA9 CELSR2 MACF1	3.55e-03	436	132	7	EFO_0005110
Disease	phospholipids:total lipids ratio	CERT1 SLC12A4 CELSR2 SYN2 MACF1	3.62e-03	227	132	5	EFO_0020946
Disease	triglycerides to total lipids in very small VLDL percentage	CERT1 PRKAG3 CELSR2	3.70e-03	69	132	3	EFO_0022341
Disease	very low density lipoprotein cholesterol measurement, phospholipid measurement	R3HDM2 CERT1 PRKAG3 CELSR2 DNAH11	3.75e-03	229	132	5	EFO_0004639, EFO_0008317
Disease	in situ carcinoma (is_marker_for)	CTNNB1 ALPL	3.94e-03	21	132	2	DOID:8719 (is_marker_for)
Disease	serum alanine aminotransferase measurement, response to combination chemotherapy	FNBP1 RNF213 CEP295	4.01e-03	71	132	3	EFO_0004735, EFO_0007965
Disease	Intellectual Disability	MYT1L ASH1L PTPN23 CERT1 PCYT2 MACF1 LARGE1	4.07e-03	447	132	7	C3714756
Disease	vitamin D measurement	ADAMTS3 CYP2J2 ASH1L RABGAP1 CELSR2 DNAH11	4.11e-03	336	132	6	EFO_0004631

Protein segments in the cluster

Peptide	Gene	Start	Entry
RTVHDMEQFGQQQYD	PKP4	356	Q99569
FDVGTRYMVNRVQDH	PFKFB1	221	P16118
RAYHLQDDGTQTVRM	ERLEC1	396	Q96DZ1
LHGTYQNLNMTVAQD	ARHGEF10L	676	Q9HCE6
EQEFRNRMIEQYHNH	ASH1L	2181	Q9NR48
RAQRAINNEMAHQLY	ELMO1	281	Q92556
VNGEAGSYEMTNQHV	CTDSPL2	106	Q05D32
YTNAVIHEVQRMGNI	CYP2J2	361	P51589
SVQRERHYNMLQFQV	ABCA4	2196	P78363
AQQTYNHLDMSVGEA	PRKAG3	406	Q9UGI9
LVDHLNVGVAQAYMN	BLOC1S1	66	P78537
GASVHDRNANSYVMV	BAG6	121	P46379
NHLNAGDITYSVRAM	ADGRL3	581	Q9HAR2
EDNQDVSAHRAVGMY	DNAH11	1666	Q96DT5
MVYQSARQEPQGQEH	AMOTL1	151	Q8IY63
SINHQMAQEDAQRLY	ANXA7	336	P20073
NAVVHYSIMSGNARG	CELSR2	431	Q9HCU4
QMHYSQQITVSLAQG	DMD	271	P11532
VRIYVDAVINHMSGN	AMY2B	106	P19961
QNNAIHYISREDMRS	CD180	181	Q99467
NNRAHSNYRAGMIID	CEMIP	726	Q8WUJ3
TNRMTVVQAYVGDVH	ATP2B2	506	Q01814
RVAAYFGMDHNVDQT	R3HDM2	206	Q9Y2K5
NSHNYRNEEMLVGRS	RBM11	106	P57052
AMHRYQVNNLGQRDL	ITGAX	951	P20702
NRHQDVMPYDSNRVV	PTPN23	1221	Q9H3S7
ISNNYIAVNQEMHNL	LRRC9	1006	Q6ZRR7
VQNHMTYSLQDVGGD	CERT1	401	Q9Y5P4
VQSGANVHAQDAMGY	ANKRD53	231	Q8N9V6
YHTMREQQAQQEDPI	RABGAP1	821	Q9Y3P9
NFTITNLQYGEDMRH	MUC16	13016	Q8WXI7
IQTYRMHIAQDINQD	NDRG3	206	Q9UGV2
VNIVEAMEHFGYRNS	PPIAL4C	136	A0A0B4J2A2
QEAEMAQNAVRLHYG	CTNNB1	476	P35222
YLQHNEIQEVGSSMR	FMOD	206	Q06828
YAQGSEVLMSRHNVG	LARGE1	516	O95461
EEQFTAAMQTQGLRH	GIGYF1	446	O75420
RNVVFVDMGHSAYQV	HSPA4	196	P34932
YHAIFDQMQQQRAED	NEK1	446	Q96PY6
VTQNAQRQYDHTMGL	MYO1A	486	Q9UBC5
ATQGEQDNYEMHVRA	MED22	51	Q15528
QDNYEMHVRAANIVR	MED22	56	Q15528
QEFDPHTVMQRNYNV	LCN9	16	Q8WX39
HTVMQRNYNVARVSG	LCN9	21	Q8WX39
ANTNRYHEMLNNVRD	KCNH5	476	Q8NCM2
DREQHSMYNLVVRGS	DSG4	226	Q86SJ6
GEVVAMDRHYFQNTG	GALNT15	366	Q8N3T1
MASQYQQPHENDVAA	CAP2	91	P40123
YHQRPTFRQMQLENV	FLNB	66	O75369
YGHSNQLRQARAMGD	PCYT2	36	Q99447
EVVHTYRQHIVNDMN	NDRG1	206	Q92597
QQQAYGMDVNHGLTE	HERC4	636	Q5GLZ8
LRYTHTGAMDSQNQD	FREM1	1351	Q5H8C1
SHDYANQSVQEDPRM	DCAF5	401	Q96JK2
ESHREISQEMTQGYQ	MYRFL	846	Q96LU7
AVQRAADHYSQQMAQ	GBP4	341	Q96PP9
AEDGSRLNQYHLMGQ	GABRA5	216	P31644
VNIVEAMEHFGYRNS	PPIAL4F	136	P0DN26
QIRSNMERQNNEYHI	KRT20	341	P35900
GGYQDDFMVVINNTH	PLEKHH2	1401	Q8IVE3
QLMTHSYINVQNGQR	MACF1	1971	Q9UPN3
VNIVEAMEHFGYRNS	PPIAL4E	136	A0A075B759
NHEGEVNRARYMPQN	RBBP7	121	Q16576
QHSNVDMLVRDVYGG	PANK4	246	Q9NVE7
SQIRMQNHFGAVRSE	NUP54	436	Q7Z3B4
VNIVEAMEHFGYRNS	PPIAL4H	136	A0A075B767
GERENVSMVDYAHNN	ALPL	426	P05186
AQQYQEMEGNLHQLS	PRICKLE2	611	Q7Z3G6
GMQRATNVTYQAHHV	PAPSS1	21	O43252
VNIVEAMEHFGYRNS	PPIAL4A	136	Q9Y536
VNIVEAMEHFGYRNS	PPIAL4G	136	P0DN37
GTVYGNIHQQLNETM	ADAMTS3	231	O15072
IRHAMNLEAVNTYEG	GCDH	401	Q92947
NLNEMNDYAGQHEVI	FNBP1	76	Q96RU3
NDYAGQHEVISENMA	FNBP1	81	Q96RU3
GNEMSAHQYLANLVG	CEP89	596	Q96ST8
ANMNYVHRDLAARNI	EPHA2	731	P29317
GLDAQVVNGYMIHDQ	SQLE	186	Q14534
YLTEQSGHMDNRQSL	DNAH14	2111	Q0VDD8
HEQQVDMQVLVYGTR	MAN2A2	791	P49641
SVNDSMHQIAINGYI	MCF2	671	P10911
VSNDEGHQTLVMYNA	CDH26	651	Q8IXH8
QHYFMGRALEERAQQ	IQCB1	491	Q15051
QHSDYGQRFQQRMQT	KIRREL1	741	Q96J84
VHTDGNEQLSVMRYS	EML1	621	O00423
AQQNMENHPVIRTLY	CSTF1	156	Q05048
GQQYESMDHIQAELS	METTL13	341	Q8N6R0
RNDYLNRHLGMVAQD	HHIPL2	186	Q6UWX4
EAGAYVEMIRNIHTN	ERICH5	316	Q6P6B1
RGENLVHQIQYREMN	CD163	1086	Q86VB7
EDSHRQMIRNYQHQL	CEP295	571	Q9C0D2
LQAMAEQLAENYHNT	RYR1	2871	P21817
AVQIARGMNYLHDEA	MAP3K9	246	P80192
RHGSRAMYTQAVQNI	PNLIPRP2	126	P54317
FEIAISNQMRQHYDR	TMEM67	831	Q5HYA8
MQADVINGSVSYQHG	FREM3	891	P0C091
HADGTYAVDMQVLRN	SYN2	156	Q92777
NGARRNHIVQYTLNM	AK9	1296	Q5TCS8
SSAHMLQVNRAYNEN	RGSL1	896	A5PLK6
RNLDAQYEMARSQTH	RSRC2	401	Q7L4I2
NHVESEMIGNYAVRF	SYT14	331	Q8NB59
HQNQSQDLELSVQMY	SEL1L3	961	Q68CR1
HIEMNFRSYDNITGQ	LGI2	261	Q8N0V4
YHSDRQLMSQVAVAG	PSMD2	781	Q13200
YRMITEGGVSINHQQ	YARS2	426	Q9Y2Z4
LDVVQAYMGHIQANA	OPLAH	946	O14841
AYMGHIQANAELAVR	OPLAH	951	O14841
TFQESNRMHAINGFV	HEPH	261	Q9BQS7
YSRMIQAAVQQRDTH	SHPK	351	Q9UHJ6
QHYENMDTRTPINNL	SHISA9	216	B4DS77
LVEYGANVTMQNHAG	SNCAIP	476	Q9Y6H5
ISRNQAHLNDMNIYE	TENM1	1521	Q9UKZ4
MVNNIIHNNEGYGVV	SHCBP1	531	Q8NEM2
MQHQYQVSNLGQRSL	ITGAM	951	P11215
QSNEETAGMVRHIYR	RDH10	71	Q8IZV5
HDTSNATLNNMRVYG	SLC12A4	241	Q9UP95
QGDALRQMQVLYGQH	STAT5A	11	P42229
SYAQAQRMVEVDLHG	BRPF1	91	P55201
QNAYQAIHNEMRGTS	AKAP3	731	O75969
MYQISQEEHSQLQEQ	CCDC136	866	Q96JN2
QNMRGNAHCVDYETQ	AGAP5	471	A6NIR3
CKQGQTHRVMEYIQQ	CLHC1	441	Q8NHS4
AYIVVQNHMNLSENA	RNF213	3691	Q63HN8
YHGEGAQQRMAQEVL	XPO1	36	O14980
HIDLVVQRTQNYMQE	NIBAN1	431	Q9BZQ8
TINHNVYEVRMENNQ	SAGE2P	211	A6NJ88
RNVVFIDMGHSAYQV	HSPA4L	196	O95757
ELQGMVEVVAENYHN	RYR3	2731	Q15413
NENSDTVGQIVHYIM	RELL1	111	Q8IUW5
IQYMLQRTQDHDENV	TNPO2	256	O14787
RVNLMGRYGDNNHSQ	TNC	2151	P24821
SAVNMGSVQGHYVQQ	PRRC2B	2171	Q5JSZ5
TYQAMVHELLGINNN	VPS45	231	Q9NRW7
MDQSHTQVSQYRQDP	TOX3	136	O15405
HNFVMVNNYEAGIET	PKHD1L1	2671	Q86WI1
SVHIYNVTLVDNGMA	PKHD1L1	3496	Q86WI1
MAQQIAYEIHLEQQS	RALGAPB	1066	Q86X10
AVVYQEQHLSIAAQM	TTC28	1056	Q96AY4
QPVYERAVHDQQMLA	ZNF75D	196	P51815
EAVQRTIHMNYEING	SLC30A4	201	O14863
GYAQSQHMEGTQINQ	TRPM8	71	Q7Z2W7
GQEEGYFRQLMINHE	ZNF461	156	Q8TAF7
QNRGIYMFRINNEHV	KMT2D	5446	O14686
RVVMQNENERNFHIY	MYO1F	196	O00160
GHGVVLSENMNDRNY	MYT1L	271	Q9UL68
EHSRNAMQIQSDNLY	NEB	1666	P20929