Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainTRPV5/TRPV6

TRPV6 TRPV5

3.89e-0521172IPR008344
PathwayKEGG_MEDICUS_VARIANT_MUTATION_CAUSED_ABERRANT_HTT_TO_CREB_MEDIATED_TRANSCRIPTION

CREB3L1 HTT CREB3L2

7.10e-0513913M47674
PathwayKEGG_MEDICUS_VARIANT_MUTATION_ACTIVATED_PRKACA_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

NR4A1 CREB3L1 CREB3L2

1.66e-0417913M47514
PathwayREACTOME_RORA_ACTIVATES_GENE_EXPRESSION

NCOA6 CHD9 HELZ2

1.98e-0418913M26942
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PRKAR1A_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

NR4A1 CREB3L1 CREB3L2

1.98e-0418913M47516
PathwayKEGG_MEDICUS_VARIANT_MUTATION_INACTIVATED_PDE11A_PDE8B_TO_ACTH_CORTISOL_SIGNALING_PATHWAY

NR4A1 CREB3L1 CREB3L2

2.74e-0420913M47517
PathwayREACTOME_FORMATION_OF_XYLULOSE_5_PHOSPHATE

CRYL1 SORD

4.07e-045912M27544
PathwayREACTOME_FORMATION_OF_XYLULOSE_5_PHOSPHATE

CRYL1 SORD

4.07e-045912MM15263
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

FLNA NCOA6 FRAS1 BICRA POLG ARHGAP17 PIGG MED13L BCL9 ITGB4 PPP1R26 HIVEP3 COQ4 PCNX4 HELZ2 HERC2 ARRDC2 HTT SMG6

9.61e-0911051211935748872
Pubmed

Functional proteomics mapping of a human signaling pathway.

FLNA NCOA6 MYO6 RBBP6 GATAD2B PPP1R26 PIGQ PELP1 DCP1B VPS41 NID1 HERC2 KIF13A SDK1

2.06e-085911211415231748
Pubmed

Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.

FLNA COPG1 LARS1 SRP68 DIDO1 GATAD2B PELP1 MTHFD1 CCAR2 TP53BP1

2.72e-073321211032786267
Pubmed

PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.

TRERF1 FLNA NCOA6 BICRA LARS1 SRP68 DIDO1 CHD9 MED13L BCL9 GATAD2B PCF11 MTHFD1 RBAK CCAR2 TP53BP1 SORD

2.93e-0711031211734189442
Pubmed

Human transcription factor protein interaction networks.

TRERF1 NCOA6 MYO6 RBBP6 BICRA LARS1 SRP68 DIDO1 BCL9 GATAD2B PCF11 DCP1B CTCF CCAR2 TAF2 HERC2 TAF1L TP53BP1 SORD

5.22e-0714291211935140242
Pubmed

Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.

TRERF1 DIDO1 BCL9 GATAD2B SENP1 NRXN1 PELP1 CTCF ZC3H4 CCAR2 PRKD1 HERC2 WNK3 TP53BP1 SMG6

1.36e-069631211528671696
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

MYO6 BICRA POLG LAMA3 CHD9 PARD3B NSRP1 PLEKHH1 HIVEP3 SENP1 PCNX4 RIN2 VPS41 PRKD1 MAPK6 HTT CREB3L2 SMG6

4.09e-0614891211828611215
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

FLNA NCOA6 RBBP6 BICRA DIDO1 NSRP1 GATAD2B PCF11 PELP1 CTCF ZC3H4 AGFG1 TAF1L TP53BP1

6.20e-069541211436373674
Pubmed

A human MAP kinase interactome.

FLNA MYO6 RBBP6 BICRA LAMA3 ARHGAP17 ITGB4 AGFG1 HERC2 MAPK6

8.21e-064861211020936779
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

ADAMTS4 MYO6 GATAD2B NCOA5 PCF11 PPP1R26 HIVEP3 SACS FIG4 HELZ2

9.30e-064931211015368895
Pubmed

A probability-based approach for high-throughput protein phosphorylation analysis and site localization.

FLNA RBBP6 DIDO1 ITGB4 NSRP1 GATAD2B DCP1B ZC3H4 KIF13A TP53BP1

1.11e-055031211016964243
Pubmed

Alteration of calcium homeostasis in primary preeclamptic syncytiotrophoblasts: effect on calcium exchange in placenta.

TRPV6 TRPV5

1.20e-052121220178461
Pubmed

The TRPV5/6 calcium channels contain multiple calmodulin binding sites with differential binding properties.

TRPV6 TRPV5

1.20e-052121222354706
Pubmed

Diverse calcium channel types are present in the human placental syncytiotrophoblast basal membrane.

TRPV6 TRPV5

1.20e-052121216564089
Pubmed

Endogenous expression of TRPV5 and TRPV6 calcium channels in human leukemia K562 cells.

TRPV6 TRPV5

1.20e-052121219295174
Pubmed

Human TRPV5 and TRPV6: key players in cadmium and zinc toxicity.

TRPV6 TRPV5

1.20e-052121223968883
Pubmed

Expression of calcium channels along the differentiation of cultured trophoblast cells from human term placenta.

TRPV6 TRPV5

1.20e-052121212390878
Pubmed

Receptor-mediated induction of aminopeptidase A (APA) of human glomerular epithelial cells (HGEC) by glucocorticoids.

AGT ENPEP

1.20e-05212121756856
Pubmed

TRPV5 and TRPV6 are expressed in placenta and bone tissues during pregnancy in mice.

TRPV6 TRPV5

1.20e-052121230916584
Pubmed

Interaction of the epithelial Ca2+ channels TRPV5 and TRPV6 with the intestine- and kidney-enriched PDZ protein NHERF4.

TRPV6 TRPV5

1.20e-052121216565876
Pubmed

Orphan nuclear receptor TR3/Nur77 improves wound healing by upregulating the expression of integrin β4.

NR4A1 ITGB4

1.20e-052121225326539
Pubmed

Age-dependent alterations in Ca2+ homeostasis: role of TRPV5 and TRPV6.

TRPV6 TRPV5

1.20e-052121216705151
Pubmed

Identification of the basement membrane protein nidogen as a candidate ligand for tumor endothelial marker 7 in vitro and in vivo.

PLXDC1 NID1

1.20e-052121216574105
Pubmed

Lack of angiotensin II conversion to angiotensin III increases water but not alcohol consumption in aminopeptidase A-deficient mice.

AGT ENPEP

1.20e-052121216889841
Pubmed

The CrebA/Creb3-like transcription factors are major and direct regulators of secretory capacity.

CREB3L1 CREB3L2

1.20e-052121221041443
Pubmed

Expression of transient receptor potential vanilloid channels TRPV5 and TRPV6 in retinal pigment epithelium.

TRPV6 TRPV5

1.20e-052121220405023
Pubmed

A single amino acid mutation results in a rapid inactivation of epithelial calcium channels.

TRPV6 TRPV5

1.20e-052121211846401
Pubmed

DNA methylation profiling in human Huntington's disease brain.

CTCF HTT

1.20e-052121226953320
Pubmed

Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell.

MYO6 OTOF

1.20e-052121219417007
Pubmed

Expression and prognostic roles of TRPV5 and TRPV6 in non-small cell lung cancer after curative resection.

TRPV6 TRPV5

1.20e-052121224761864
Pubmed

Fast and slow inactivation kinetics of the Ca2+ channels ECaC1 and ECaC2 (TRPV5 and TRPV6). Role of the intracellular loop located between transmembrane segments 2 and 3.

TRPV6 TRPV5

1.20e-052121212077127
Pubmed

Blended phenotype of combination of HERC2 and AP3B2 deficiency and Angelman syndrome caused by paternal isodisomy of chromosome 15.

AP3B2 HERC2

1.20e-052121234042275
Pubmed

[The functional characteristics oF TRPV5 and TRPV6 channels in normal and transformed human blood lymphocytes].

TRPV6 TRPV5

1.20e-052121224592736
Pubmed

Homo- and heterotetrameric architecture of the epithelial Ca2+ channels TRPV5 and TRPV6.

TRPV6 TRPV5

1.20e-052121212574114
Pubmed

Structural conservation of the genes encoding CaT1, CaT2, and related cation channels.

TRPV6 TRPV5

1.20e-052121211549322
Pubmed

[TRPV5 and TRPV6 calcium channels in human T cells].

TRPV6 TRPV5

1.20e-052121219140341
Pubmed

First evidence of TRPV5 and TRPV6 channels in human parathyroid glands: possible involvement in neoplastic transformation.

TRPV6 TRPV5

1.20e-052121225164318
Pubmed

Activation of OASIS family, ER stress transducers, is dependent on its stabilization.

CREB3L1 CREB3L2

1.20e-052121222705851
Pubmed

Regulation of the mouse epithelial Ca2(+) channel TRPV6 by the Ca(2+)-sensor calmodulin.

TRPV6 TRPV5

1.20e-052121215123711
Pubmed

Single-channel activities of the human epithelial Ca2+ transport proteins CaT1 and CaT2.

TRPV6 TRPV5

1.20e-052121211719848
Pubmed

Concerted action of associated proteins in the regulation of TRPV5 and TRPV6.

TRPV6 TRPV5

1.20e-052121217233615
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TRERF1 FLNA NCOA6 RBBP6 DIDO1 BCL9 GATAD2B PCF11 ZC3H4 HELZ2 CCAR2 TP53BP1

1.73e-057741211215302935
Pubmed

TIF1beta/KAP-1 is a coactivator of the orphan nuclear receptor NGFI-B/Nur77.

NR4A1 GATAD2B PELP1

1.81e-0515121319321449
Pubmed

USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.

EFCAB5 FLNA NCOA6 SENP1 PELP1 OTOF KIF13A

1.88e-05234121736243803
Pubmed

USP45 and Spindly are part of the same complex implicated in cell migration.

FLNA COPG1 LARS1 TRDN MTHFD1 WNK3 TP53BP1

1.93e-05235121730258100
Pubmed

SENP1 knockdown-mediated CTCF SUMOylation enhanced its stability and alleviated lipopolysaccharide-evoked inflammatory injury in human lung fibroblasts via regulation of FOXA2 transcription.

SENP1 CTCF

3.59e-053121237914145
Pubmed

Localisation of Nup153 and SENP1 to nuclear pore complexes is required for 53BP1-mediated DNA double-strand break repair.

SENP1 TP53BP1

3.59e-053121228576968
Pubmed

Lack of pendrin HCO3- transport elevates vestibular endolymphatic [Ca2+] by inhibition of acid-sensitive TRPV5 and TRPV6 channels.

TRPV6 TRPV5

3.59e-053121217200157
Pubmed

Age-dependent changes in the expression of klotho protein, TRPV5 and TRPV6 in mouse inner ear.

TRPV6 TRPV5

3.59e-053121219922080
Pubmed

WNK3 positively regulates epithelial calcium channels TRPV5 and TRPV6 via a kinase-dependent pathway.

TRPV5 WNK3

3.59e-053121218768590
Pubmed

Identification of BSPRY as a novel auxiliary protein inhibiting TRPV5 activity.

TRPV6 TRPV5

3.59e-053121216380433
Pubmed

Globular domains 4/5 of the laminin alpha3 chain mediate deposition of precursor laminin 5.

LAMA3 ITGB4

3.59e-053121215316072
Pubmed

A molecular determinant of phosphoinositide affinity in mammalian TRPV channels.

TRPV6 TRPV5

3.59e-053121227291418
Pubmed

Calbindin-D28K dynamically controls TRPV5-mediated Ca2+ transport.

TRPV6 TRPV5

3.59e-053121216763551
Pubmed

Direct interaction with Rab11a targets the epithelial Ca2+ channels TRPV5 and TRPV6 to the plasma membrane.

TRPV6 TRPV5

3.59e-053121216354700
Pubmed

Translocation-positive low-grade fibromyxoid sarcoma: clinicopathologic and molecular analysis of a series expanding the morphologic spectrum and suggesting potential relationship to sclerosing epithelioid fibrosarcoma: a study from the French Sarcoma Group.

CREB3L1 CREB3L2

3.59e-053121217721195
Pubmed

High-sensitivity profiling of SARS-CoV-2 noncoding region-host protein interactome reveals the potential regulatory role of negative-sense viral RNA.

COPG1 SRP68 OAS3 GATAD2B PCF11 POLR1E MTHFD1 HELZ2 CCAR2

4.07e-05469121937314180
Pubmed

A genome-wide study of common SNPs and CNVs in cognitive performance in the CANTAB.

NRXN1 MTHFD1 VPS41 DSEL

5.11e-0558121419734545
Pubmed

Human GW182 Paralogs Are the Central Organizers for RNA-Mediated Control of Transcription.

NCOA6 PCF11 CCAR2 TP53BP1

5.47e-0559121428813667
Pubmed

The SOX2-interactome in brain cancer cells identifies the requirement of MSI2 and USP9X for the growth of brain tumor cells.

TRERF1 SRP68 CHD9 PELP1 CCAR2 TAF2 SMG6

6.14e-05282121723667531
Pubmed

HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.

FLNA COPG1 LARS1 SRP68 DIDO1 FIG4 POLR1E COQ4 PCNX4 ROS1 KIF13A

6.81e-057541211135906200
Pubmed

TRIM44 mediated p62 deubiquitination enhances DNA damage repair by increasing nuclear FLNA and 53BP1 expression.

FLNA TP53BP1

7.17e-054121234211088
Pubmed

Alpha 6 integrins participate in pro-T cell homing to the thymus.

ITGB4 F8

7.17e-05412127621877
Pubmed

Novel transcription factors in human CD34 antigen-positive hematopoietic cells.

DIDO1 RBAK

7.17e-054121212070015
Pubmed

Invasive breast cancer induces laminin-332 upregulation and integrin β4 neoexpression in myofibroblasts to confer an anoikis-resistant phenotype during tissue remodeling.

LAMA3 ITGB4

7.17e-054121222673183
Pubmed

Functional expression of the epithelial Ca(2+) channels (TRPV5 and TRPV6) requires association of the S100A10-annexin 2 complex.

TRPV6 TRPV5

7.17e-054121212660155
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

FLNA MYO6 RBBP6 LARS1 NSRP1 GATAD2B MTHFD1 ZC3H4 TP53BP1

7.28e-05506121930890647
Pubmed

New interaction partners for Nek4.1 and Nek4.2 isoforms: from the DNA damage response to RNA splicing.

FRAS1 MYO6 ABCA13 ITGB4 AP3B2 NID1 CCAR2 HERC2 SMG6

8.08e-05513121925798074
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

NCOA6 MYO6 SRP68 BCL9 TRDN ZFAND4 PLEKHH1 CRYL1 POLR1E TAF2

8.21e-056381211031182584
Pubmed

Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.

MYO6 POLG LARS1 DIDO1 CHD9 NR4A1 ITGB4 NSRP1 SNX14 RIN2 RPGR KIF13A

9.62e-059251211228986522
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

FLNA COPG1 SRP68 DIDO1 PELP1 CTCF HELZ2 CCAR2 HERC2 TP53BP1

9.94e-056531211022586326
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FLNA MYO6 RBBP6 LARS1 SRP68 DIDO1 NSRP1 CTCF MTHFD1 ZC3H4 AGFG1 TP53BP1

1.05e-049341211233916271
Pubmed

Mouse screen reveals multiple new genes underlying mouse and human hearing loss.

TMPRSS15 COPG1 MYO6 LARS1 ARHGAP17 CHD9 USH1C CREB3L1 DEFB103A ELL2 CTCF POLR1E COQ4 RBAK

1.10e-0412421211430973865
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

MED13L NRXN1 MUC5AC TP53BP1

1.13e-0471121433541421
Pubmed

FUS-CREB3L2/L1-positive sarcomas show a specific gene expression profile with upregulation of CD24 and FOXL1.

CREB3L1 CREB3L2

1.19e-045121221536545
Pubmed

IAP insertion in the murine LamB3 gene results in junctional epidermolysis bullosa.

LAMA3 ITGB4

1.19e-04512129271670
Pubmed

Role and regulation of TRP channels in neutrophil granulocytes.

TRPV6 TRPV5

1.19e-045121212765698
Pubmed

MUC5AC interactions with integrin β4 enhances the migration of lung cancer cells through FAK signaling.

ITGB4 MUC5AC

1.19e-045121226751774
Pubmed

Adaptor protein-3 produces synaptic vesicles that release phasic dopamine.

AP3B2 VPS41

1.19e-045121237812725
Pubmed

Studies on dehydrogenases of the glucuronate-xylulose cycle in the livers of diabetic mice and rats.

CRYL1 SORD

1.19e-045121238160
Pubmed

Calcium transport genes are differently regulated in maternal and fetal placenta in the knockout mice of calbindin-D(9k) and -D(28k).

TRPV6 TRPV5

1.19e-045121222407925
Pubmed

Optineurin links myosin VI to the Golgi complex and is involved in Golgi organization and exocytosis.

MYO6 HTT

1.19e-045121215837803
Pubmed

The synaptic proteins neurexins and neuroligins are widely expressed in the vascular system and contribute to its functions.

F8 NRXN1

1.19e-045121219926856
Pubmed

Laminin 5 regulates polycystic kidney cell proliferation and cyst formation.

LAMA3 ITGB4

1.19e-045121216870608
Pubmed

Complete sequence, recombinant analysis and binding to laminins and sulphated ligands of the N-terminal domains of laminin alpha3B and alpha5 chains.

LAMA3 NID1

1.19e-045121211829758
Pubmed

Basement membrane localization of Frem3 is independent of the Fras1/Frem1/Frem2 protein complex within the sublamina densa.

FRAS1 NID1

1.19e-045121217596926
Pubmed

Targeting USP10 induces degradation of oncogenic ANLN in esophageal squamous cell carcinoma.

FLNA MYO6 RBBP6 LARS1 LAMA3 SRP68 DIDO1 OAS3 ITGB4 NCOA5 PELP1 POLR1E MTHFD1 HELZ2

1.25e-0412571211436526897
Pubmed

Interactome of vertebrate GAF/ThPOK reveals its diverse functions in gene regulation and DNA repair.

MYO6 POLG SRP68 CREB3L1 GATAD2B TRPV5 CREB3L2

1.37e-04321121732098917
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

SP5 MUC5AC SORD

1.40e-0429121321402740
Pubmed

Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

NCOA6 MED13L NRXN1 ZC3H4 HELZ2 SMG6

1.42e-04225121612168954
Pubmed

Assessment of a polymorphism of SDK1 with hypertension in Japanese Individuals.

LAMA3 DIDO1 PIGG PIGQ SDK1

1.44e-04142121519851296
Pubmed

Association of genetic variants with hemorrhagic stroke in Japanese individuals.

LAMA3 DIDO1 PIGG PIGQ SDK1

1.49e-04143121520198315
Pubmed

F-box and WD repeat domain-containing-7 (Fbxw7) protein targets endoplasmic reticulum-anchored osteogenic and chondrogenic transcriptional factors for degradation.

CREB3L1 CREB3L2

1.78e-046121223955342
Pubmed

Genetic risk factors for placental abruption: a HuGE review and meta-analysis.

MTHFD1 AGT

1.78e-046121218277167
Pubmed

The zinc-finger transcription factor, early growth response 3, mediates VEGF-induced angiogenesis.

NR4A1 PRKD1

1.78e-046121218059339
Pubmed

The phosphorylation status of PAS-B distinguishes HIF-1alpha from HIF-2alpha in NBS1 repression.

PRKD1 TP53BP1

1.78e-046121217024177
Pubmed

Junctional Epidermolysis Bullosa

LAMA3 ITGB4

1.78e-046121220301304
Pubmed

Norbin Stimulates the Catalytic Activity and Plasma Membrane Localization of the Guanine-Nucleotide Exchange Factor P-Rex1.

MTHFD1 AP3B2

1.78e-046121226792863
Pubmed

alpha3beta1 and alpha6beta4 integrin receptors for laminin-5 are not essential for epidermal morphogenesis and homeostasis during skin development.

ITGB4 NID1

1.78e-046121210934043
Pubmed

Menin and Menin-Associated Proteins Coregulate Cancer Energy Metabolism.

NCOA6 RBBP6 DIDO1 GATAD2B SENP1 ZC3H4 TP53BP1

1.99e-04341121732971831
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TMPRSS15 ABCA13 TRDN NRXN1 NRK ROS1 SDK1

3.82e-0818412082cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TMPRSS15 ABCA13 TRDN NRXN1 NRK ROS1 SDK1

3.82e-081841208ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FRAS1 TMPRSS15 ABCA13 TRDN NRXN1 NRK ROS1 SDK1

3.82e-0818412082b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellPBMC-Control-cDC_1|Control / Compartment, Disease Groups and Clusters

NPIPB15 OAS3 PLEKHH1 RTP5 OTOF HELZ2

4.16e-0615612069b6c5bcac516a62bcc1f5be32ffa8c92735ef0bc
ToppCellCOVID-19-Heart-VSMC|Heart / Disease (COVID-19 only), tissue and cell type

FLNA ADAMTS4 LAMA3 ELL2 ENPEP SDK1

9.15e-061791206a69ad6912b5c10bb9f9d800f724c792341e9bab1
ToppCellE15.5-Mesenchymal-mesenchymal_fibroblast-alveolar_fibroblast_Wnt2-pa|E15.5 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

MYO6 CREB3L1 HIVEP3 COLEC12 NID1 ENPEP

9.15e-061791206b559f5a72cc9e3e35d05cb539b5c2e006e56e652
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 COLEC12 RIN2 AGT SDK1 FBN3

1.01e-051821206d3a037268f026eb2f84428b1821022503cef7756
ToppCellAdult-Epithelial-basal_cell|Adult / Lineage, Cell type, age group and donor

FRAS1 CACHD1 ITGB4 TMEM59L TRPV6 RNF207

1.04e-05183120600a6b19ca49e3b8e0d1cd387a3515b0ff4b81c81
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPIPB15 ABCA13 PARD3B PLEKHH1 MUC5AC SDK1

1.07e-05184120601c19a830348ab0b9c02c1546a439de70ee10f97
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B PLEKHG2 F8 CREB3L1 UNC5A POLR1E

1.14e-05186120637860daeecd6d412bd3797f30496a56da667fbd1
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B PLEKHG2 F8 CREB3L1 UNC5A POLR1E

1.14e-05186120660830822d3de3147816693404fd03392e04c2b8e
ToppCelldroplet-Liver-Hepatocytes-18m-Endothelial-endothelial_cell_of_hepatic_sinusoid|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PARD3B PLEKHG2 F8 CREB3L1 UNC5A POLR1E

1.14e-051861206baebeffdd426ce767190ddefc857cc78e6a58d36
ToppCell10x3'2.3-week_14-16-Mesenchymal_myocytic-stroma-muscle_stem_cell|week_14-16 / cell types per 3 fetal stages;per 3',per 5'

FRAS1 MYO6 COLEC12 NRXN1 NRK PRKD1

1.21e-051881206de6f4889e0c5f39fbbaefd85526f645c6afa09d5
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

FRAS1 LAMA3 CACHD1 NR4A1 ROS1 FBN3

1.28e-0519012068aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

LAMA3 CACHD1 NR4A1 ELL2 ROS1 PRKD1

1.32e-05191120634cc997e4e5c727495f321e6807a84aa124da486
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA3 C9orf152 TMEM59L SP5 ROS1 FBN3

1.36e-051921206fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA3 C9orf152 TMEM59L SP5 ROS1 FBN3

1.36e-05192120687b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellbackground-Cholangiocytes|background / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 USH1C FAM135B C9orf152 TRPV6 ARRDC2

1.40e-0519312069152241073dbe02ac2c11d86bec9b5b529196f6e
ToppCellPBMC-Mild|PBMC / Compartment, Disease Groups and Clusters

FLNA OAS3 NR4A1 MED13L OTOF HELZ2

1.44e-051941206d1366b169d14011194e61d16b6b0953349febc78
ToppCellwk_20-22-Epithelial-Distal_epithelial-type_II_pneumocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

LAMA3 C9orf152 TMEM59L SP5 ROS1 FBN3

1.49e-05195120645d1acd316d0ced97dfb150c3a943128d8fa4e7e
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_neuro-secretory-Neuroendocrine|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

USH1C FAM135B NRXN1 OTOF AP3B2 TMEM59L

1.53e-0519612064bdc304c0c9d8bebe1a6a8a27e44acd1e8113725
ToppCellBronchial-NucSeq-Stromal-Myofibroblastic-Muscle_perivascular_immune_recruiting|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAMTS4 PCDHB8 AGT NID1 ENPEP SDK1

1.58e-051971206cfb3dc4b401800e33c82cfc3baee69dbbd16ac8c
ToppCellParenchymal-NucSeq-Epithelial-Epi_airway_secretory-Secretory_Goblet|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ABCA13 PLEKHH1 MUC5AC RNF207 SDK1 SORD

1.62e-051981206af07a970afaa435c6433bb5c1cbff4c67af350c7
ToppCellTracheal-NucSeq-Epithelial-Epi_airway_basal-Basal|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FRAS1 ABCA13 LAMA3 CACHD1 ITGB4 SDK1

1.67e-05199120694a7867e800df352731796de8c24cba133c29622
ToppCellNS-control-d_0-4-Epithelial-Secretory|d_0-4 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

CHD9 CREB3L1 PLEKHH1 ELL2 RNF207 SORD

1.67e-05199120632bdfff40fd442b88489c8b0f79af3927a51a03c
ToppCellcontrol-Epithelial-Secretory|control / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

CHD9 CREB3L1 PLEKHH1 ELL2 RNF207 SORD

1.67e-051991206262e5b8a52c8ddb0b47048c786e8bdb7158e1b9a
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial|10w / Sample Type, Dataset, Time_group, and Cell type.

FLNA FRAS1 TRDN ITGB4 RIN2 NID1

1.72e-052001206ff0b2675c68e9fc1fa16b3276431f199f3642eac
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMA3 COLEC12 RIN2 AGT SDK1 FBN3

1.72e-052001206501a3b93624df463458a35d3e6648d4ccc941724
ToppCellNeuronal-Inhibitory-iA-iA_3(VIP)-VIP_3-CHRM2-L1-3|Neuronal / cells hierarchy compared to all cells using T-Statistic

LAMA3 COLEC12 RIN2 AGT SDK1 FBN3

1.72e-052001206d1f36a8232411933b1494168ec912fd0e5246428
ToppCellBrain_organoid-organoid_Tanaka_cellReport-10w-Neuroepithelial-Proteoglycan-expressing_cell|10w / Sample Type, Dataset, Time_group, and Cell type.

FLNA FRAS1 TRDN ITGB4 RIN2 NID1

1.72e-05200120607d2133c85e0a4eb8bef653ee15ecd0f1b2bbd44
ToppCellAT2_cells-IPF_02|World / lung cells shred on cell class, cell subclass, sample id

FRAS1 ITGB4 NRK TMEM59L ROS1

2.82e-051311205ff4e618bd944f852bbd34438f740187aca82460f
ToppCellfacs-Liver-Non-hepatocytes-3m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABHD12B F8 FAM135B AP3B2 NID1

6.30e-0515512058fdda4e3657ac56188ae88ed3caf145f4d9d1567
ToppCellASK452-Epithelial-Type_2|ASK452 / Donor, Lineage and Cell class of Lung cells from Dropseq

ABHD12B NCOA5 ACSM3 ROS1 PRKD1

6.50e-051561205e2b8d65c38cedb8ec6c3c1b138957145af931c51
ToppCell3'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NR4A1 PLEKHH1 NRXN1 C9orf50 SDK1

7.11e-05159120522427ad4ad2e797e4664e7a7b0514094f22a18b2
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 MYO6 BEND2 TRPV6 TRPV5

7.11e-05159120550d951cf27a571c0c5002003c16fbc370fa17eb1
ToppCellTCGA-Cervix-Primary_Tumor-Endocervical_Adenocarcinoma-Mucinous_Adenocarcinoma-7|TCGA-Cervix / Sample_Type by Project: Shred V9

USH1C CREB3L1 UNC5A C9orf152 MUC5AC

7.11e-05159120575a82bbabd97b168dbf1c3f43a9bdad48ce18c78
ToppCellBAL-Control-cDC_6|Control / Compartment, Disease Groups and Clusters

EFCAB5 COPG1 RTP5 PELP1 DSEL

9.22e-05168120565ec473cff748b334c0a66e33bc34a8465fe7631
ToppCellControl|World / group, cell type (main and fine annotations)

MYO6 LAMA3 PARD3B ROS1 MUC5AC

9.22e-051681205a3511faf2cd2c2b9c8363c8b99da3f3609c43ed6
ToppCellmetastatic_Lymph_Node-Myeloid_cells-Microglia/Mac|Myeloid_cells / Location, Cell class and cell subclass

CFAP251 ARSK CREB3L1 ARRDC2 MUC5AC

9.48e-051691205dba8f5599aa21feef5b7fdfed2e3ab54748d80f7
ToppCellChildren_(3_yrs)-Epithelial-lung_neuroendocrine_cell_(PNEC)-D139|Children_(3_yrs) / Lineage, Cell type, age group and donor

SH2D6 USH1C NRXN1 AP3B2 WNK3

9.48e-05169120596a2aec9acf8a6f966973c035e5ade456cf47772
ToppCellControl-Epithelial_cells-Airway_basal|Control / group, cell type (main and fine annotations)

FRAS1 ABCA13 CACHD1 ITGB4 SDK1

1.00e-0417112053965ced4be6db14265a90673502fceee425837ca
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(non-nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPIPB9 CREB3L1 KIF13A MUC5AC SORD

1.09e-04174120542f2ba54b4ea4c62482582b0ccdadffae0a5eb4a
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Endothelial-blood_vessel_endothelial_cell_of_kidney-capillary-immature_endothelial_cell-Glomerular_Capillary_Endothelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

ABHD12B F8 UNC5A RIN2 RPGR

1.15e-04176120564e426f5e84884ce2c29acf6f4b958962a63927f
ToppCellE16.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF2-AF2_prolif|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TRERF1 ABCA13 CREB3L1 NRK HELZ2

1.18e-04177120530f82b04e48940bfcaf2c22677efe6d57ae3f1a7
ToppCellTCGA-Ovary-Primary_Tumor-Ovarian_Carcinoma-Serous_Cystadenocarcinoma-6|TCGA-Ovary / Sample_Type by Project: Shred V9

ADAMTS4 PLXDC1 CREB3L1 COLEC12 NID1

1.21e-041781205142879e9393e721f9b05a6bb46995c9d6d713c95
ToppCellPrimary_Visual_cortex_(V1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

RTP5 RIN2 DSEL SDK1 FBN3

1.21e-0417812053c973aac16988e88f5677d3d695dd772ccfd6570
ToppCelldroplet-Fat-Scat-21m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRDN NRK CCAR2 SORD SBK3

1.21e-0417812055fc9f41609735b972a2cd0830182d13742cd5bf5
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

NPIPB15 ABCA13 NR4A1 PLEKHH1 MUC5AC

1.24e-0417912056e965e424eebef50f0202cff75f458be395cfca1
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 CACHD1 NRK TRPV6 TRPV5

1.24e-041791205666072c0e8448dbaec1683d18368ec2502453f90
ToppCellCOVID-19-Heart-Pericyte|COVID-19 / Disease (COVID-19 only), tissue and cell type

ADAMTS4 PLXDC1 AGT NID1 ENPEP

1.31e-04181120533cac65ed1ea5e7bd72250495df4f850b143d5aa
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 RIN2 DSEL SDK1 FBN3

1.31e-04181120535bcdcd2651149692e5b150e887c0f450c81d2d4
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-4_VIP_DSEL|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 RIN2 DSEL SDK1 FBN3

1.31e-04181120570eff83dd85691e977972c660731394d2fcf5cdf
ToppCelldroplet-Kidney-KIDNEY-30m-Epithelial-collecting_duct_principal_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TRERF1 FRAS1 ITGB4 UNC5A SDK1

1.31e-0418112057af469f5bcb9b1ab3f35b2758bf2afb87e8eba57
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L2-5_VIP_TOX2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 RIN2 DSEL SDK1 FBN3

1.31e-041811205154d5e586cab25155c6d06dfe6ae01203b88e0fb
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1-AT1_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 ABCA13 LAMA3 MTHFD1 TMEM59L

1.34e-041821205573771130247e869e4e58f22d4a1cb31989635cf
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

MYO6 LAMA3 HIVEP3 NRK PRKD1

1.34e-041821205a8cc56f32efe180e8fb5d69dbe606a794b3db700
ToppCellPND14-Epithelial-Epithelial_Alveolar-Epithelial_Alveolar-AT1|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FRAS1 ABCA13 LAMA3 MTHFD1 TMEM59L

1.34e-0418212056cfaa2b3b3974c13b01c943f4adb70768dcc35e4
ToppCellRA-13._Vascular_Smooth_Muscle|RA / Chamber and Cluster_Paper

FLNA LAMA3 KIF13A ENPEP SDK1

1.38e-041831205818fd886e0188091310825f9145fa53328f2c979
ToppCellRA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FLNA LAMA3 PRKD1 ENPEP SDK1

1.38e-041831205cae2ee08f985a6f005b4b8e959e465350315156a
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-fibroblast|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CREB3L1 COLEC12 SP5 NID1 ENPEP

1.41e-041841205fea4fe648e9749177d0783443dc26a7df5807883
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 RIN2 DSEL SDK1 FBN3

1.41e-04184120532473dbdb2de66391157c5814ef34e790806e4f2
ToppCellCOVID-19-Heart-Pericyte|Heart / Disease (COVID-19 only), tissue and cell type

ADAMTS4 PLXDC1 PLEKHG2 AGT ENPEP

1.41e-04184120521790cdfa3b4036ad413fd44b94e31563116f25f
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal-nan|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CREB3L1 COLEC12 SP5 NID1 ENPEP

1.41e-04184120596a8a0a190bc293655fe7d80cbed8119c0da25f2
ToppCelldroplet-Large_Intestine-COLON_PROXIMAL-30m-Epithelial-Lgr5+_undifferentiated_cell|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ACSM3 MTHFD1 SP5 ROS1 SORD

1.41e-041841205e7b9c69fc77040c5191ad8089697051e2589c30e
ToppCellfacs-Skin-Skin_Anagen-18m-Mesenchymal|Skin / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CREB3L1 COLEC12 SP5 NID1 ENPEP

1.41e-041841205780eb72da43527f0c72effac3423ec7384f05f20
ToppCellP03|World / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

FLNA HIVEP3 COLEC12 NID1 ENPEP

1.45e-041851205a07dbe1f76e40734a28826423a5cc64b8e56af5e
ToppCell343B-Fibroblasts-Fibroblast-E-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

POLG BCL9 ZFAND4 NCOA5 ARRDC2

1.45e-0418512051b8e3ddb91797f84e4b15d2457b0c008e5be50db
ToppCell343B-Fibroblasts-Fibroblast-E|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

POLG BCL9 ZFAND4 NCOA5 ARRDC2

1.45e-04185120502cbf492bc40abebaa93a3a208888afae72fbe06
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2-Inh_L1-3_VIP_ZNF322P1|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 COLEC12 RIN2 SDK1 FBN3

1.45e-0418512050b5a0df58ae2ad8261f40f152775747af4f3937a
ToppCelldroplet-Liver-LIVER_HEP-30m-Endothelial-nan|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

F8 HIVEP3 UNC5A SP5 CCAR2

1.45e-041851205bdd2e6cb20294b39a9d856004bf57ba69cf877e2
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 RIN2 DSEL SDK1 FBN3

1.56e-0418812056ee3f8f94ea7bdf652c9575fc65bff08070093a4
ToppCelldroplet-Large_Intestine-COLON:P+D-30m-Epithelial|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NR4A1 CREB3L1 C9orf152 ACSM3 SORD

1.56e-041881205bfd3b4f57785596b2bd2c657e0d2d8b0f40ba36d
ToppCellLA-13._Vascular_Smooth_Muscle|LA / Chamber and Cluster_Paper

FLNA LAMA3 PRKD1 KIF13A SDK1

1.56e-04188120534e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

ABCA13 CACHD1 COLEC12 ROS1 PRKD1

1.56e-041881205ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCell5'-Adult-Distal_Rectal-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAMTS4 NR4A1 AP3B2 NID1 WNK3

1.60e-041891205f7d57723b8fb0f1e1485f51e3eff93ec0f39761e
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

USH1C FAM135B ACSM3 ENPEP SDK1

1.60e-0418912053b48b0d220cc24d5170713d61fa91f5bb6c21841
ToppCellLA-13._Vascular_Smooth_Muscle|World / Chamber and Cluster_Paper

FLNA LAMA3 PRKD1 KIF13A SDK1

1.60e-0418912056b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

USH1C FAM135B ACSM3 ENPEP SDK1

1.60e-04189120528b502611829e4a24caff2562545c7db97686099
ToppCellrenal_cortex_nuclei-Adult_normal_reference|renal_cortex_nuclei / Celltypes from Cells and Nuclei per compartment and clinical group

FRAS1 NR4A1 FAM135B CRYL1 ELL2

1.60e-041891205a48df46274d51e84ffb40264646de7346104efb9
ToppCelldroplet-Kidney-nan-3m-Mesenchymal-fibroblast|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAMTS4 CREB3L1 COLEC12 NRK NID1

1.64e-041901205f61e21d53f2f7804ac6e40ab6c7f69838aa94d6a
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 LAMA3 PLEKHH1 ACSM3 TMEM59L

1.64e-041901205625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

USH1C FAM135B ACSM3 ENPEP SDK1

1.64e-041901205989d4eefd22d66ecb857836f8fdbcf41e3047f84
ToppCellLV-01._Fibroblast_I|World / Chamber and Cluster_Paper

CHD9 COLEC12 ACSM3 NRK NID1

1.64e-04190120512992ec80a7b4f4f17de693f0719ee061a9918fd
ToppCellSomatosensory_Cortex_(S1)-Non-neuronal-Macroglial-Astro-Astrocyte-Astro_L1-6_FGFR3_ETNPPL|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PARD3B CACHD1 ITGB4 COLEC12 AGT

1.64e-041901205b56c55f608b30f7379941ac7d5f0f5200f305fca
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

USH1C FAM135B CRYL1 ENPEP SDK1

1.68e-0419112053c464645d0e7e423f791bd63bf5bcf11f6b590d3
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

USH1C FAM135B CRYL1 ENPEP SDK1

1.68e-0419112051c1d13144259b998d4a0e85142f7afef2ef1e63f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO6 LAMA3 CACHD1 ROS1 FBN3

1.68e-041911205ca5669bd6f4a17471acae3eb229f845cc2e08efa
ToppCellLV-02._Fibroblast_II|World / Chamber and Cluster_Paper

CHD9 COLEC12 ACSM3 NRK NID1

1.68e-041911205d36565257ccba8c1bbed2c1c01be66a9cbb5f834
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 PLXDC1 ARHGAP17 PLEKHG2 NID1

1.68e-0419112057b0d42a877540dbb346a76a62403e0d5d3e07fa6
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRAS1 PARD3B NID1 PRKD1 SDK1

1.68e-0419112056688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Mesenchymal-Myocytic_interstitial_cell-Vascular_Smooth_Muscle_Cell_/_Pericyte-|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

TRERF1 PLXDC1 ARHGAP17 PLEKHG2 NID1

1.68e-041911205cd854b9c426924fdc84bf7f411f6dea447143e79
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

PARD3B CREB3L1 NRK DSEL ENPEP

1.72e-0419212058d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCellhuman_hepatoblastoma-Tumor_cells|World / Sample and Cell Type and Tumor Cluster (all cells)

FRAS1 PARD3B MED13L PRKD1 SDK1

1.72e-041921205916fbec1c7ab7969bda711886ac88e877e30c280
ToppCellPND07|World / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLNA NR4A1 AGT NID1 ENPEP

1.72e-0419212058171a60df481195c39a7f740effcae8e4deb6ca7
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_VIP_2|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

LAMA3 RIN2 DSEL SDK1 FBN3

1.72e-0419212056a252e298f8a454623fa9c1c893a7a45a886d694
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_2|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

FRAS1 PARD3B NID1 PRKD1 SDK1

1.72e-04192120599ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

FRAS1 LAMA3 ACSM3 TMEM59L SP5

1.72e-041921205b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MYO6 LAMA3 CACHD1 ROS1 PRKD1

1.72e-041921205fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellfacs-Aorta-Heart-3m|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LAMA3 F8 RIN2 HERC2 ENPEP

1.72e-0419212051ccc47792edf9ee23501c8e2165d11271636b66a
ToppCellSmart-start-Cell-Wel_seq-Neoplastic-Stem-like-OPC-like-OPC-like-F|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

FRAS1 OTOF NRK ITIH6 TAF1L

1.76e-041931205315840bc48899f3a36d57b19197509de19716e3d
Diseasemucopolysaccharidosis (is_implicated_in)

ARSK HYAL1

1.48e-0521142DOID:12798 (is_implicated_in)
DiseaseFibromyxosarcoma

CREB3L1 CREB3L2

4.43e-0531142C3714524
DiseaseHerlitz Disease

LAMA3 ITGB4

8.83e-0541142C0079683
DiseaseEpidermolysis Bullosa Progressiva

LAMA3 ITGB4

8.83e-0541142C0079297
DiseaseAdult junctional epidermolysis bullosa (disorder)

LAMA3 ITGB4

1.47e-0451142C0268374
DiseaseEPIDERMOLYSIS BULLOSA, JUNCTIONAL, LOCALISATA VARIANT (disorder)

LAMA3 ITGB4

1.47e-0451142C2608084
Diseasejunctional epidermolysis bullosa non-Herlitz type (implicated_via_orthology)

LAMA3 ITGB4

1.47e-0451142DOID:0060738 (implicated_via_orthology)
DiseaseJunctional Epidermolysis Bullosa

LAMA3 ITGB4

2.20e-0461142C0079301
Diseasejunctional epidermolysis bullosa (is_implicated_in)

LAMA3 ITGB4

3.07e-0471142DOID:3209 (is_implicated_in)
DiseaseNeurodevelopmental Disorders

PARD3B MED13L HIVEP3 ZC3H4

4.73e-04931144C1535926
Diseasemitral valve prolapse (is_implicated_in)

FLNA AGT

5.23e-0491142DOID:988 (is_implicated_in)
DiseaseAsthma, Occupational

PRKD1 HERC2

6.52e-04101142C0264423
DiseaseRS-10-hydroxywarfarin to RS-warfarin ratio measurement

FRAS1 NRXN1 RIN2 FBN3

8.90e-041101144EFO_0803335
Diseasemultiple myeloma

DIDO1 ELL2 HERC2 DSEL

9.52e-041121144EFO_0001378
DiseaseNonsyndromic Hearing Loss and Deafness, Autosomal Recessive

MYO6 USH1C OTOF

1.02e-03511143cv:CN043650
Diseaseneuropsychological test

FAM135B NRXN1 MTHFD1 VPS41 DSEL

1.03e-031971145EFO_0003926
Diseasephosphocreatine measurement

TRDN RIN2

1.12e-03131142EFO_0010521
Diseasegastric ulcer (implicated_via_orthology)

AGT MUC5AC

1.31e-03141142DOID:10808 (implicated_via_orthology)
DiseaseProteinuria

CRYL1 SMG6

1.50e-03151142HP_0000093
Diseaseage-related hearing impairment

MYO6 MED13L CRYL1 FIG4 PCNX4 MAPK6

1.65e-033241146EFO_0005782
DiseaseCannabis use

SDK1 SMG6

1.71e-03161142EFO_0007585
DiseaseIntellectual Disability

MED13L SNX14 NRXN1 SACS CTCF TAF2 HTT

1.79e-034471147C3714756
DiseaseNecrotizing Enterocolitis

CRYL1 SORD

1.94e-03171142C0520459
DiseaseProfound Mental Retardation

MED13L SNX14 NRXN1 TAF2

2.11e-031391144C0020796
DiseaseMental Retardation, Psychosocial

MED13L SNX14 NRXN1 TAF2

2.11e-031391144C0025363
DiseaseMental deficiency

MED13L SNX14 NRXN1 TAF2

2.11e-031391144C0917816
DiseaseNonsyndromic genetic hearing loss

MYO6 USH1C OTOF

3.22e-03761143cv:C5680182
Diseasetransient cerebral ischemia (biomarker_via_orthology)

ADAMTS4 NRXN1 AGT HTT

3.27e-031571144DOID:224 (biomarker_via_orthology)
Diseaseosteoarthritis, knee

PARD3B SENP1 MAPK6 SMG6

3.35e-031581144EFO_0004616
Diseasefrailty measurement

MAPK6 HTT

3.55e-03231142EFO_0009885

Protein segments in the cluster

PeptideGeneStartEntry
ISSGPIQKPGIFISH

USH1C

226

Q9Y6N9
TAPGQHLKFQPLTLE

TMEM59L

291

Q9UK28
APPLLHVAALGQKQG

CCAR2

126

Q8N163
LTFHPGSQVVKLPFI

ARSK

46

Q6UWY0
KEFQVLLQHSPSPIG

SMG6

921

Q86US8
QQTPILGPLKGDHSQ

C9orf50

216

Q5SZB4
LLTAPHKLQGTSGPL

CREB3L1

246

Q96BA8
PSIQFQGLHGLVKIP

ELL2

56

O00472
HTLPLPEGFQVVKVG

CTCF

156

P49711
PGFQHNLLCKSPTLL

ABHD12B

336

Q7Z5M8
LHAVANPGLISLTGP

CACHD1

761

Q5VU97
LHPPTSGTIIINGKN

ABCA13

3891

Q86UQ4
KPNNLSLVVHGPGDL

SORD

6

Q00796
QAPGFLTDIHTGKPL

FBN3

1706

Q75N90
IKNALAHFLPQGTPT

MT-ATP6

121

P00846
QLPPTLVTSFEGKHG

ARRDC2

111

Q8TBH0
GVFTAPGLHLKQPFV

AGT

201

P01019
PGLHLKQPFVQGLAL

AGT

206

P01019
LHVGTPKLPAGISIQ

AP3B2

906

Q13367
GLQILPVDGNPHKTS

CFAP251

871

Q8TBY9
QAHLLVLPKGGNTPA

C9orf152

56

Q5JTZ5
TQQLHPVLQKPSVFG

NSRP1

16

Q9H0G5
PLKLFPSQATHQLGE

NR4A1

206

P22736
DSSIHGPGPIFVKNI

PARD3B

401

Q8TEW8
LLNPGFVGPLVNIHT

HOXC12

6

P31275
PVAAPVGGISFHLQI

PRKD1

41

Q15139
HVNGSLILPIGSIKP

FRAS1

1106

Q86XX4
PLPTQIHIKSLTGFG

MED13L

1761

Q71F56
PLPKTQANHGALQFG

LAMA3

2976

Q16787
KGPGSIPLQDQHLAL

HERC2

276

O95714
GPFVKLNTAPDGHLI

TMPRSS15

736

P98073
SLQPQPLGLKQFFHL

BEND2

96

Q8NDZ0
HQLKDLPGTNLFIPG

PCNX4

841

Q63HM2
QFHSPVGSPLKSIQA

MAPK6

681

Q16659
HRNFILTGIPGTPDK

OR51H1

11

Q8NH63
PPGTHLLFAQTGKIE

NID1

941

P14543
GGHPPAIQSLINLLA

NCOA5

336

Q9HCD5
HGQLIKNFTILQGPP

COLEC12

431

Q5KU26
SSGIKHNIFNPPIIA

F8

2151

P00451
GHPVLLPFSQSGVLI

MUC5AC

156

P98088
PSGNAFLKINPDHIG

ENPEP

611

Q07075
QPSPAHVGQQGLSKL

GATAD2B

211

Q8WXI9
GQHGKTPSPQKLDNL

NPIPB7

46

O75200
TEPNGLILFSHGKPR

NRXN1

511

Q9ULB1
ANHLGLSVPGLVSVP

PELP1

706

Q8IZL8
VQLSNPKFGAHLGQP

ITGB4

1081

P16144
GQHGKTPSPQKLDNL

NPIPB15

46

A6NHN6
GQSLLHGQLIPTTGP

RBBP6

476

Q7Z6E9
NLGPGSAPSKLHVSQ

PCF11

246

O94913
VVGPLHIPQNIKFSS

NCOA6

1696

Q14686
PEPQHLSLTALFGKQ

DCP1B

221

Q8IZD4
GQLGLTEIHKNPPTI

EFCAB5

1206

A4FU69
LSGHGPLAQPLTLQV

ADAMTS4

771

O75173
FNRNKPPNHVSLGLT

CHD9

2446

Q3L8U1
LGHKRNSGVPAFLTP

HTT

2376

P42858
INLFLGVFHPTEGKP

FIG4

591

Q92562
LIDVKFNGTHIPGSP

FLNA

2401

P21333
AGSQVHSPGINPLKS

BCL9

851

O00512
HLPTSPLQKGLLAAG

COQ4

41

Q9Y3A0
GAQKGPIPSLFSGQH

DIDO1

1801

Q9BTC0
HGLGVSTAQPALVPK

ITIH6

641

Q6UXX5
HPQLGALTSQAPKGL

ITIH6

791

Q6UXX5
SEGIKHVLQTFGPIP

CRYL1

256

Q9Y2S2
PVFGGLPQNASLIAH

HYAL1

91

Q12794
LHLLGQEGPKTTNPS

COPG1

456

Q9Y678
KSPPGHFGLLLLLSQ

nan

31

Q6ZN92
QTLFPITHQPLGSFG

FAM135B

1061

Q49AJ0
QLGTSLQHGFLVPSP

HELZ2

1886

Q9BYK8
LLGLQGPPTVLTHQA

BICRA

166

Q9NZM4
FKTEPGLPQIHLEGN

SDK1

106

Q7Z5N4
AHPGLLQTLAGPLQT

SBK3

96

P0C264
LPLSLETGLPFHVNG

SACS

2871

Q9NZJ4
GPKLSHLNNVLVFAP

DSEL

491

Q8IZU8
LSHNPEQKGVPTGFI

MTHFD1

871

P11586
VPVPGHGGIINTLQK

DEFB103A

16

P81534
GQHGKTPSPQKLDNL

NPIPB9

61

F8W1W9
LLTAPHKLQGSGPLV

CREB3L2

251

Q70SY1
VKAAQGLGLHAFPPV

OTOF

936

Q9HC10
SGLGHPIQLDPNQKT

OAS3

351

Q9Y6K5
QLLKPVLPNIQGHSF

PCDHB8

766

Q9UN66
LVGPHASGVNSILPK

KIF13A

1191

Q9H1H9
GAFFKLSPPGQRHQL

NRK

111

Q7Z2Y5
KLGLPNQLLGNHRTP

RPGR

221

Q92834
SALGPGVPHIINTKL

POLR1E

296

Q9GZS1
LNNGLVPVGKHTPTV

RTP5

311

Q14D33
GGHIPLGLVFLVQPA

POLG

231

A0A3B3IS91
GQKIPIFSAAGLPHN

ATP6V1B2

186

P21281
PLCQHQTVLKGPSGL

RNF207

61

Q6ZRF8
SLGLTPQKTHLQPSF

SP5

91

Q6BEB4
GGTLNRKHISPAFQP

ARHGAP17

511

Q68EM7
LVNPQPSNGHFSTKI

LARS1

1071

Q9P2J5
TSPFLGSLHPGQLLQ

TAF1L

746

Q8IZX4
SLDQPKGGLHFVVPS

TAF2

151

Q6P1X5
QHPASGGLKQSLTPV

PIGQ

721

Q9BRB3
PHGSQPFTLAVLLRG

SH2D6

96

Q7Z4S9
NSVFKTHLLPQTGFP

SENP1

21

Q9P0U3
LLPPGLNSQTGGHKT

PPP1R26

566

Q5T8A7
SLVTKQANLVHFPPG

SRP68

566

Q9UHB9
VLFAPDQLGIHSPGL

ACTRT1

261

Q8TDG2
GIQVLPNRPFGLFTH

ACSM3

426

Q53FZ2
LHLNKGTPSQSPVVG

AGFG1

171

P52594
QLKSPEGHLILPTFN

C15orf32

106

Q32M92
LQAQPPGIFLVHKST

RIN2

111

Q8WYP3
PKQLGLQELFPQGHS

SNX14

86

Q9Y5W7
PQFNNVLSTVKPGHI

SAGE2P

226

A6NJ88
LVNSAFDGHQPLPKG

RBAK

521

Q9NYW8
GLGVPTPQTLQLHSL

SEPTIN12

81

Q8IYM1
GSFVAPGLHPQSQLL

HIVEP3

131

Q5T1R4
PNHQGLTPFKLAGVE

TRPV6

276

Q9H1D0
NPFPHLITLLGNKIV

ROS1

1151

P08922
TPIRGNLLHFPSSQG

TP53BP1

1056

Q12888
KPPFITGLLNNIGTH

VPS41

706

P49754
PGGTSPAKAQHLLQQ

PLEKHH1

1156

Q9ULM0
DGPSPKFQLTNGHLL

UNC5A

386

Q6ZN44
GVHNLPVPTLFGTVK

ZC3H4

1246

Q9UPT8
IFVHGDLKPGQSPAI

TRDN

276

Q13061
AGLPTIHTGQKPSQG

ZNF155

136

Q12901
GLHVSNLPKQDLPGI

PLEKHG2

916

Q9H7P9
NNLSPKTKGTPVHLG

PLXDC1

411

Q8IUK5
SSLPRQTKHFLGNLP

ZFAND4

361

Q86XD8
IGHISGPNSPLIGQK

PIGG

221

Q5H8A4
PNHQGLTPFKLAGVE

TRPV5

236

Q9NQA5
LLLHLGSQPPVGKTF

nan

36

Q9UFV3
LSKPALQVGQHPTQG

TRERF1

216

Q96PN7
QILKGLQFLHTRTPP

WNK3

256

Q9BYP7
QGKSLGTRPPHVFAI

MYO6

116

Q9UM54