Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainFAM193_C

FAM193B FAM193A

9.15e-062572PF15914
DomainFAM193_C

FAM193B FAM193A

9.15e-062572IPR031802
DomainFAM193

FAM193B FAM193A

9.15e-062572IPR029717
DomainIon_trans_dom

KCNG2 KCNA3 TRPM3 TRPM2

4.05e-04114574IPR005821
DomainIon_trans

KCNG2 KCNA3 TRPM3 TRPM2

4.05e-04114574PF00520
DomainBromodomain_CS

PBRM1 TAF1

2.84e-0326572IPR018359
DomainK_chnl_volt-dep_Kv

KCNG2 KCNA3

3.06e-0327572IPR003968
PathwayBIOCARTA_RAC1_PATHWAY

MYLK PIK3CA VAV1

2.93e-0521413MM1463
Pubmed

A genome-wide short hairpin RNA screening of jurkat T-cells for human proteins contributing to productive HIV-1 replication.

IFI44 TNNC2 INPP5F PAIP1 NRP1 FAM149A

1.57e-0621857619460752
Pubmed

X-linked dystonia parkinsonism syndrome (XDP, lubag): disease-specific sequence change DSC3 in TAF1/DYT3 affects genes in vesicular transport and dopamine metabolism.

DSC3 TAF1

2.64e-06257223184149
Pubmed

Positive regulation of Vav1 by Themis controls CD4 T cell pathogenicity in a mouse model of central nervous system inflammation.

THEMIS VAV1

2.64e-06257238565808
Pubmed

[Role of phosphatidylinositol 3-kinase and myosin light chain kinase during the activation of thrombin receptors].

MYLK PIK3CA

2.64e-06257219549383
Pubmed

Themis1 enhances T cell receptor signaling during thymocyte development by promoting Vav1 activity and Grb2 stability.

THEMIS VAV1

1.58e-05457227188442
Pubmed

CTL-associated antigen-4 ligation induces rapid T cell polarization that depends on phosphatidylinositol 3-kinase, Vav-1, Cdc42, and myosin light chain kinase.

MYLK VAV1

1.58e-05457217579061
Pubmed

Global mapping of herpesvirus-host protein complexes reveals a transcription strategy for late genes.

DSC3 OSBPL6 RECQL ZZEF1 PAIP1 NDUFS5 GNPAT

2.60e-0553357725544563
Pubmed

The Sensory Coding of Warm Perception.

TRPM3 TRPM2

2.63e-05557232208171
Pubmed

TRIM33 drives prostate tumor growth by stabilizing androgen receptor from Skp2-mediated degradation.

PBRM1 XPO5 RECQL PSPC1 CASZ1

3.10e-0522057535785414
Pubmed

A synaptic temperature sensor for body cooling.

TRPM3 TRPM2

3.94e-05657234672983
Pubmed

PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.

KCNA3 MYLK DDX60

4.26e-054157321282332
Pubmed

The in vivo Interaction Landscape of Histones H3.1 and H3.3.

PBRM1 POLA1 RSF1 RECQL TAF1 MIER1 CASZ1

5.98e-0560857736089195
Pubmed

The lymphoid lineage-specific actin-uncapping protein Rltpr is essential for costimulation via CD28 and the development of regulatory T cells.

THEMIS MYLK VAV1

6.03e-054657323793062
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PBRM1 MYO1D XPO5 POLA1 RSF1 XRN1 RECQL

9.33e-0565357722586326
Pubmed

Interchangeability of Themis1 and Themis2 in thymocyte development reveals two related proteins with conserved molecular function.

THEMIS VAV1

1.44e-041157222732588
Pubmed

Protein-protein interaction panel using mouse full-length cDNAs.

PBRM1 PGRMC2 PSPC1 GNPAT

1.44e-0416157411591653
Pubmed

Fibril treatment changes protein interactions of tau and α-synuclein in human neurons.

PBRM1 XPO5 XRN1 INPP5F PSPC1 PTGES3

1.64e-0449857636634849
Pubmed

Dynamic expression of the TRPM subgroup of ion channels in developing mouse sensory neurons.

TRPM3 TRPM2

1.72e-041257219850157
Pubmed

Paralog knockout profiling identifies DUSP4 and DUSP6 as a digenic dependence in MAPK pathway-driven cancers.

KCNA3 MYLK TRPM3 TNNC2 TAF1 INPP5F PSPC1

1.85e-0473057734857952
Pubmed

Local anesthetics impair the growth and self-renewal of glioblastoma stem cells by inhibiting ZDHHC15-mediated GP130 palmitoylation.

MTMR12 KIAA1217 RSF1

2.20e-047157333541421
Pubmed

The C. elegans homolog of human panic-disorder risk gene TMEM132D orchestrates neuronal morphogenesis through the WAVE-regulatory complex.

TMEM132D PAIP1 NDUFS5

2.30e-047257333726789
Pubmed

Understanding the development of oral epithelial organs through single cell transcriptomic analysis.

DSC3 OSBPL6 PRSS23

2.39e-047357335831953
Pubmed

Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PBRM1 TAF1 DNAH7

2.59e-047557325593309
Pubmed

Generalization of variants identified by genome-wide association studies for electrocardiographic traits in African Americans.

THEMIS TMEM132D

3.97e-041857223534349
Pubmed

Deficiency of TRPM2 leads to embryonic neurogenesis defects in hyperthermia.

TRPM3 TRPM2

3.97e-041857231911949
Pubmed

Heterozygous expression of the oncogenic Pik3ca(H1047R) mutation during murine development results in fatal embryonic and extraembryonic defects.

PIK3CA NRP1

4.43e-041957225958091
Pubmed

Identification and functional characterization of transcriptional activators in human cells.

PBRM1 RECQL TAF1 CASZ1 GNPAT

4.92e-0439857535016035
Pubmed

Biochemistry of mammalian peroxisomes revisited.

ACOX3 GNPAT

4.92e-042057216756494
Pubmed

Quantitative interactomics in primary T cells unveils TCR signal diversification extent and dynamics.

THEMIS VAV1

4.92e-042057231591574
Pubmed

TNF-α inhibits glucocorticoid receptor-induced gene expression by reshaping the GR nuclear cofactor profile.

PBRM1 MYO1D RSF1 DNAH7 CASZ1 FAM149A

6.11e-0463857631182584
Pubmed

Prediction of the coding sequences of unidentified human genes. XVIII. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro.

TRPM3 USP37 MIER1

6.21e-0410157310997877
Pubmed

Use of genome-wide expression data to mine the "Gray Zone" of GWA studies leads to novel candidate obesity genes.

NPY1R PRSS23

6.53e-042357220532202
Pubmed

Mapping the expression of transient receptor potential channels across murine placental development.

TRPM3 TRPM2

7.12e-042457233884443
Pubmed

International Union of Pharmacology. XLIX. Nomenclature and structure-function relationships of transient receptor potential channels.

TRPM3 TRPM2

7.73e-042557216382100
Pubmed

Recruitment of the Mammalian Histone-modifying EMSY Complex to Target Genes Is Regulated by ZNF131.

ING1 XPO5 XRN1

7.95e-0411057326841866
Pubmed

N-Terminal Acetyltransferase Naa40p Whereabouts Put into N-Terminal Proteoform Perspective.

FAM193B FAM193A KIAA1217 PGRMC2 RSF1 XRN1 PTGES3

8.09e-0493457733916271
Pubmed

An introduction to TRP channels.

TRPM3 TRPM2

9.02e-042757216460286
Pubmed

Global landscape of HIV-human protein complexes.

DSC3 XPO5 OSBPL6 RECQL PTGES3

9.15e-0445757522190034
Pubmed

RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.

FAM193A KIAA1217 XRN1 PDZD4

9.22e-0426357434702444
Pubmed

Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.

PBRM1 ING1 TAF1 CASZ1

9.88e-0426857433640491
Pubmed

A Degradation Motif in STAU1 Defines a Novel Family of Proteins Involved in Inflammation.

FAM193A MYO1D POLA1 DDX60 XRN1 RECQL

1.17e-0372457636232890
Pubmed

Embryonic forebrain transcriptome of mice with polyalanine expansion mutations in the ARX homeobox gene.

KCNA3 NRP1

1.19e-033157227798109
Pubmed

NOTCH1 nuclear interactome reveals key regulators of its transcriptional activity and oncogenic function.

PBRM1 XPO5 VAV1

1.26e-0312957323022380
Pubmed

S100A3 a partner protein regulating the stability/activity of RARα and PML-RARα in cellular models of breast/lung cancer and acute myeloid leukemia.

S100A3 PSPC1

1.27e-033257230532072
Pubmed

Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.

PBRM1 XPO5 POLA1 RSF1 RECQL TAF1 PSPC1

1.30e-03101457732416067
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

TRPM3 TRPM2

1.35e-033357219834762
Pubmed

Nuclear actin interactome analysis links actin to KAT14 histone acetyl transferase and mRNA splicing.

MYO1D ING1 POLA1 PSPC1 PTGES3

1.44e-0350657530890647
Pubmed

CCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cells.

MTMR12 NRP1

1.52e-033557223716698
Pubmed

A cryptic Tudor domain links BRWD2/PHIP to COMPASS-mediated histone H3K4 methylation.

PBRM1 RSF1

1.60e-033657229089422
Cytoband11q14.1

RSF1 PRSS23

1.26e-034257211q14.1
CoexpressionLTE2_UP.V1_DN

NPY1R DDX60 IFI44 PRSS23 INPP5F PSPC1 NRP1

2.19e-07195577M2721
CoexpressionMEK_UP.V1_DN

NPY1R MYLK DDX60 IFI44 INPP5F

6.46e-05194575M2724
CoexpressionGSE2706_2H_VS_8H_R848_STIM_DC_DN

PIK3CA DDX60 XRN1 IFI44 INPP5F

6.78e-05196575M4730
CoexpressionERBB2_UP.V1_DN

NPY1R DDX60 IFI44 RECQL INPP5F

6.95e-05197575M2635
CoexpressionGSE23502_WT_VS_HDC_KO_MYELOID_DERIVED_SUPPRESSOR_CELL_COLON_TUMOR_UP

PILRB XPO5 XRN1 AP1M2 MIER1

7.46e-05200575M8085
CoexpressionGSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_UP

RCBTB1 POLA1 PRSS23 INPP5F NRP1

7.46e-05200575M7981
CoexpressionAtlasFacebaseRNAseq_e9.5_Olfactory Placode_top-relative-expression-ranked_2500_k-means-cluster#5

DOK5 MYLK MYO1D KIAA1217 GPR173 AP1M2 COMMD3

8.14e-05391577Facebase_RNAseq_e9.5_Olfactory Placode_2500_K5
CoexpressionAtlasFacebaseRNAseq_e10.5_Mandibular Arch_top-relative-expression-ranked_2500_k-means-cluster#4

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.25e-04290576Facebase_RNAseq_e10.5_Mandibular Arch_2500_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_top-relative-expression-ranked_2500_k-means-cluster#3

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.45e-04298576Facebase_RNAseq_ratio_e9.5_MandibularArch_vs_MaxillaryArch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Maxillary Arch_top-relative-expression-ranked_2500_k-means-cluster#3

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.64e-04305576Facebase_RNAseq_e9.5_Maxillary Arch_2500_K3
CoexpressionAtlasFacebaseRNAseq_e9.5_Facial Mesenchyne_top-relative-expression-ranked_2500_k-means-cluster#4

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.70e-04307576Facebase_RNAseq_e9.5_Facial Mesenchyne_2500_K4
CoexpressionAtlasFacebaseRNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_top-relative-expression-ranked_2500_k-means-cluster#3

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.82e-04311576Facebase_RNAseq_ratio_e9.5_MaxillaryArch_vs_Mandibular_2500_K3
CoexpressionAtlasFacebaseRNAseq_e8.5_Paraxial Mesoderm_top-relative-expression-ranked_2500_k-means-cluster#2

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.89e-04313576Facebase_RNAseq_e8.5_Paraxial Mesoderm_2500_K2
CoexpressionAtlasFacebaseRNAseq_e8.5_Non-Floor Plate Neural Epithelium_top-relative-expression-ranked_2500_k-means-cluster#4

DOK5 MYLK MYO1D GPR173 AP1M2 COMMD3

1.99e-04316576Facebase_RNAseq_e8.5_Non-Floor Plate Neural Epithelium_2500_K4
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)-Glut_D_(IT_RORB_THEMIS_LINC00507)_6-Exc_L5-6_THEMIS_TMEM233|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

DOK5 THEMIS MYO1D PRSS23 NRP1

3.34e-06179575747a32460b257fffca30527b56a74720eb9c12e4
ToppCellMild-CD8+_T_activated|World / Disease group and Cell class

THEMIS KCNA3 DDX60 XRN1 IFI44

5.19e-0619657579632190e44fcef9d7c11d9b9e37f2ebf0e6e255
ToppCellcontrol|World / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

DSC3 MYO1D KIAA1217 PRSS23 CASZ1

5.73e-0620057597f36d2c197e03d93a1fc59949d77ae90f6e6a9a
ToppCell10x5'-Liver-Myeloid_Mac-Intestinal_macrophages|Liver / Manually curated celltypes from each tissue

KIAA1217 GPR173 NRP1 LARGE1

4.76e-051565749a897fc79c4fae94c5f2e9012d65297f9225e5e3
ToppCellnormal_Lung-Myeloid_cells-Undetermined|Myeloid_cells / Location, Cell class and cell subclass

DOK5 KIAA1217 OSBPL6 DNAH7

5.38e-05161574283012858e575c70d09950de53da041509f59bfa
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0.5|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

TRPM3 AP1M2 PRSS23 PDZD4

6.20e-05167574e242827999caad08b0894d88ab97bc1df41b7650
ToppCellAnterior_Cingulate_gyrus_(CgG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Anterior_Cingulate_gyrus_(CgG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNG2 TRPM3 KIAA1217 NRP1

6.65e-05170574021c3e45955d18e241f7d98acdf22076fee4fc43
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Granulocytic-Neutrophil-Neu_c5-GSTP1(high)OASL(low)|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM193A DDX60 XRN1 IFI44

6.65e-0517057407b561cd9c528bc8444c9385e1de621eee7b697e
ToppCellLeuk-UTI-Myeloid-cDC1|Leuk-UTI / Disease, Lineage and Cell Type

DOK5 MYLK OSBPL6 FAM149A

7.11e-05173574226bb8d881f32d65c60f5e4c034c6d465f8e7ba5
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c08-IL2RB|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

FAM193A MYLK DDX60 PRSS23

7.11e-051735745295ed31648abf8edff214cf67cd4769f20f9e6d
ToppCellprimary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_E_(THEMIS)|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPY1R THEMIS MYO1D TMEM132D

7.27e-05174574bc978a2148a0261a4f9d1ca5479b707e224566be
ToppCellTCGA-Cervix-Primary_Tumor-Cervical_Carcinoma-Non-keratinizing_Cervical_Squamous_Cell_Carcinoma-3|TCGA-Cervix / Sample_Type by Project: Shred V9

DSC3 PIK3CA XRN1 FAM83C

7.44e-051755740cc215109d9915af47e4d0a120ce2e46910715fa
ToppCellLPS-IL1RA+antiTNF|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MYO1D TRPM3 KIAA1217 NRP1

7.77e-05177574b7fee75de7e96924af488a5baa2334711889ae7c
ToppCellfacs-Liver-Liver_non-hepato/SCs-18m-Lymphocytic-CD8-positive,_alpha-beta_T_cell|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

THEMIS KCNA3 CASZ1 PDZD4

7.77e-05177574b8de0fc92691a6d6759c743195b11edd2d63f265
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-kidney_interstitial_fibroblast_5|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

7.94e-0517857478a0c6340001a77f5b2d890b6263f574af2e72da
ToppCellMid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

KCNG2 TRPM3 KIAA1217 NRP1

8.29e-05180574a499548391e6833b78f6e920f8e32a755814a9da
ToppCelldroplet-Limb_Muscle-Pre-Sort|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK TNNC2 PRSS23 NDUFS5

8.29e-05180574af2bafcd1b2082629de3ea336711add01565c4c4
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

NPY1R TRPM3 KIAA1217 NRP1

8.29e-05180574b514c55e52b46e8a1a2f09ed2c59a7683367a505
ToppCelldroplet-Limb_Muscle-Pre-Sort-18m|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MYLK TNNC2 PRSS23 NDUFS5

8.29e-05180574f29a995cf6e1a1836ed68b73258d9370bf3d4434
ToppCellChildren_(3_yrs)-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)|Children_(3_yrs) / Lineage, Cell type, age group and donor

MYO1D TMEM132D KIAA1217 FAM149A

9.22e-0518557498b8ee42b89d97e4c9db01740e0c193503c68f2c
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPY1R MYLK PRSS23 NDUFS5

9.22e-0518557430df02fbe2828e3c4f3e5c4cda855e74fb31be39
ToppCellCOVID-19_Severe-CD8+_T_activated|COVID-19_Severe / Disease condition and Cell class

DDX60 IFI44 PRSS23 PTGES3

9.41e-05186574fc087b79240fe7ada5810d4f4b3c7287eab598ff
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TRPM3 TMEM132D DNAH7 NRP1

9.41e-05186574f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellTCGA-Pancreas-Primary_Tumor-Pancreatic_Adenocarcinoma-Ductal_Adenocarcinoma-1|TCGA-Pancreas / Sample_Type by Project: Shred V9

PBRM1 MYLK TAF1 USP37

9.41e-0518657403db813598b67b1e08f759758a1c2023396921fa
ToppCelldroplet-Heart-4Chambers-21m-Mesenchymal-smooth_muscle_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NPY1R MYLK PRSS23 NDUFS5

9.61e-051875748ff9f771d10c372d771c92dfa9006aa81aec4681
ToppCellT_cells-ISG-high_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

KCNA3 DDX60 XRN1 IFI44

9.81e-051885746f8946d4710f6e32c937213f99b790b098b8819c
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

MTMR12 RCBTB1 PRSS23 PAIP1

1.00e-04189574160963355256f7c0f2138da80c90de478f5a9fe8
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.02e-041905742306aa9dbeaef3be8484a5b236605de23cd75d4c
ToppCellSevere-B_activate-7|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)

PILRB DDX60 IFI44 CASZ1

1.02e-0419057467e6c8a5a8724bdf2861fd76a711319dfc71d47a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.02e-041905741f83f7f24288a3b9ab33c2e113e845dba96adc8a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.04e-04191574a58c75e9580139fb370b498d95660f10f3a2a27b
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.06e-041925749093a9e94a25682d109a7f6edc256a25a61103a0
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.06e-04192574bc84b9ce01b4d826a682842ab8a395dac9b91183
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.06e-041925749ed5d49621ec1aa01716dc369bba1450b5f015f5
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R MYLK TNNC2 PRSS23

1.06e-0419257426d9207e72bbef5e0046de511e2c9ff752b726f3
ToppCellCV-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

THEMIS DDX60 XRN1 IFI44

1.06e-041925742a2052b44e8f679ef484f03ba4fb37b0ec841b88
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-high_collagen-matrisome_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.06e-041925740ab1176cfbb0de8dd1f22c6e2c41265cf6c10ee1
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC-VSMC_mature|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R MYLK TNNC2 PRSS23

1.09e-041935749a2c1711dec9dd8c8313bcf25bb888ac8e86c3f3
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R MYLK PRSS23 NRP1

1.09e-04193574f1199518c3626fd29bfce65070dd21a660671213
ToppCellPND10-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R MYLK TNNC2 PRSS23

1.09e-041935747fc3ab7261c88c1df71744bf5b17e8e46c4300e0
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular-VSMC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R MYLK TNNC2 PRSS23

1.09e-041935747c7aa5e2124830d0fa1df11b6413ec6cf780aad0
ToppCellCF-Lymphoid-B_cell|Lymphoid / Disease state, Lineage and Cell class

MYO1D PIK3CA INPP5F LARGE1

1.09e-041935747ebf20344a9a154fd2cffa281526867fcf0aded3
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.11e-0419457481713e0409e8be695ba5dfdc67a997b33435dd9e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.11e-04194574e03ba6caed59fa64d4d9b042593469d4a6a3dc10
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-Collagen-low_Matrisome-low_fibroblast-|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

NPY1R KIAA1217 PRSS23 NRP1

1.11e-04194574627cffe2d448e74fc5df92e74e5b922a73304137
ToppCellIPF-Multiplet-Multiplet|IPF / Disease state, Lineage and Cell class

MYO1D KIAA1217 OSBPL6 DNAH7

1.13e-04195574fce0c29574bb7aab181b9c00feb42681e285d1f2
ToppCellB_cells-ISG-high_B_cells|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis

DDX60 XRN1 IFI44 CASZ1

1.13e-04195574b64d9e1a8834401b4dc501566546647754ae21fc
ToppCellIPF-Multiplet|IPF / Disease state, Lineage and Cell class

MYO1D KIAA1217 OSBPL6 DNAH7

1.13e-04195574eacc0449ae6f3ad8002268cd061467684c6fb9a7
ToppCellBronchial-NucSeq-Epithelial-Epi_airway_secretory|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

KIAA1217 PRSS23 CASZ1 FAM149A

1.13e-04195574e7230a849ea31e6eef9bc6f5468938499450582d
ToppCellMild-CD4+_T_activated|World / Disease group and Cell class

KCNA3 DDX60 XRN1 IFI44

1.15e-04196574417b4fc2e4388f34c410576131b02936f93e46b6
ToppCellPosterior_cortex-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Bcl6-Excitatory_Neuron.Slc17a7.Bcl6-Cbln1_(Layer_5a,_entorhinal_cortex_,_Cbln1+)|Posterior_cortex / BrainAtlas - Mouse McCarroll V32

AP1M2 TNNC2 LCT

1.17e-04745730be24b07a2503a16ece1489e765200be4c7253cc
ToppCellPND14-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_vascular|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NPY1R MYLK TNNC2 PRSS23

1.17e-041975741a6b2ca94a4634c24cd95481576c955b20000a5f
ToppCellsystemic_lupus_erythematosus-treated|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DDX60 XRN1 IFI44 PTGES3

1.20e-041985748165ff735095c52994fb5057d89be93cc378b7da
ToppCellsystemic_lupus_erythematosus-flare|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

DDX60 XRN1 IFI44 PTGES3

1.20e-041985744c93ee921d56132d80832d8e94563f32ccf13bbc
ToppCellMild-CD8+_T_activated|Mild / Disease group and Cell class

THEMIS DDX60 XRN1 IFI44

1.20e-04198574ceac1b51bacfd0dd7fe7c6a666f7927055e1f380
ToppCellCOVID-19_Moderate|World / disease group, cell group and cell class

THEMIS DDX60 XRN1 IFI44

1.22e-04199574952fac67588ad5676f5939e3c7f8bac803c27064
ToppCellmild-CD8+_Tem|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

THEMIS DDX60 XRN1 PRSS23

1.24e-04200574d8aec4904c9420b8f9d7508658ba1e36c66cdfcc
ToppCellMacroglial-Astrocytes-SLC14A1---|Macroglial / cells hierarchy compared to all cells using T-Statistic

TRPM3 OSBPL6 DNAH7 NRP1

1.24e-04200574d6fcbf4f4bc1b89a9929d7b114c6b907b6979900
ToppCellMacroglial-Astrocytes-SLC14A1----L1-6|Macroglial / cells hierarchy compared to all cells using T-Statistic

TRPM3 OSBPL6 DNAH7 NRP1

1.24e-04200574f861509b54185d89931db64da1b9d81986cc7938
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-CD4+_T_activated|COVID-19_Mild / Disease, condition lineage and cell class

THEMIS KCNA3 DDX60 IFI44

1.24e-04200574d9e8a0d047d4403fb7265fde7448e23a7780785c
ToppCellMacroglial-Astrocytes-SLC14A1|Macroglial / cells hierarchy compared to all cells using T-Statistic

TRPM3 OSBPL6 DNAH7 NRP1

1.24e-0420057416f468217427921fa18c6d078ffa990eb019b257
ToppCellCOVID-19-COVID-19_Mild-Lymphocyte-T/NK-NK_activated|COVID-19_Mild / Disease, condition lineage and cell class

DDX60 IFI44 PRSS23 PDZD4

1.24e-042005742281debd86e5d92e8fe0397aec9ef670800f7471
ToppCellControl_saline-Endothelial-Endothelial-Activated_Alv_Cap|Control_saline / Treatment groups by lineage, cell group, cell type

DDX60 KIAA1217 IFI44 NRP1

1.24e-04200574be55cef682ba87250dad97689332c8820b3a7420
ToppCellMacroglial-Astrocytes-SLC14A1--|Macroglial / cells hierarchy compared to all cells using T-Statistic

TRPM3 OSBPL6 DNAH7 NRP1

1.24e-042005740442894c39eec69850c090957a5dc7bcecd21e04
ToppCellParenchymal-10x3prime_v2-Stromal-Peri/Epineurial_-NAF_epineurial|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

PIK3CA KIAA1217 INPP5F USP37

1.24e-04200574be46efc899d06c55ee297bee3126f69bcdb2048b
ToppCellNS-control|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

MYO1D KIAA1217 PRSS23 CASZ1

1.24e-04200574ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCellMacroglial-Astrocytes-SLC14A1-|Macroglial / cells hierarchy compared to all cells using T-Statistic

TRPM3 OSBPL6 DNAH7 NRP1

1.24e-0420057401819446deeab9054f5cfe889d53bb49d137dbc0
DiseaseSquamous cell carcinoma of mouth

ING1 PIK3CA

3.52e-055562C0585362
DiseaseNonorganic psychosis

NPY1R PBRM1 TRPM2

3.10e-0469563C0349204
DiseaseAmphetamine-Related Disorders

NPY1R TRPM3 LARGE1

3.97e-0475563C0236733
DiseaseAmphetamine Abuse

NPY1R TRPM3 LARGE1

3.97e-0475563C0236807
DiseaseAmphetamine Addiction

NPY1R TRPM3 LARGE1

3.97e-0475563C0236804
DiseasePsychotic Disorders

NPY1R PBRM1 TRPM2

9.46e-04101563C0033975
Diseaselung small cell carcinoma (is_implicated_in)

PBRM1 XPO5

1.30e-0328562DOID:5409 (is_implicated_in)
DiseaseBreast Cancer, Familial

PIK3CA RECQL

1.49e-0330562C0346153

Protein segments in the cluster

PeptideGeneStartEntry
FCEYFKELEEESIRD

AP1M2

91

Q9Y6Q5
RCKRIFEYDFLSVED

ACOX3

81

O15254
LEGFRRFDLYEDCKD

CASZ1

1431

Q86V15
TEREVEYFKRFCLDS

FAM193A

1226

P78312
RYDAEDLEEFCFKFC

RCBTB1

481

Q8NDN9
FRDEDVFVCESRYSA

PBRM1

1051

Q86U86
ELDEDDLCYEFRRER

LARGE1

436

O95461
IDEDFELTERECIKY

MYLK

1551

Q15746
YFAFDRKEDDDECLE

FAM149A

411

A5PLN7
LRVFQFCLRYTKEEE

MTMR12

146

Q9C0I1
DYDRSRCQFDEKSRD

DDX60

511

Q8IY21
LRVCDDYDVSRDEFF

KCNG2

56

Q9UJ96
DEEYERYRELLEIKC

PDZD4

351

Q76G19
ATFCLDKDALRDEYD

PGRMC2

156

O15173
FCLETLPEFRDEKDY

KCNA3

251

P22001
EEEKRFIRATADVFC

LCT

1191

P09848
RLEKFSDERAAYFRC

DOK5

41

Q9P104
YECIREDKGFRFFSE

OSBPL6

656

Q9BZF3
QLTDEEKYRDCERFK

POLA1

1266

P09884
EAEREEFFDETRRLC

PIK3CA

76

P42336
EIEEAYEKFCLESER

PAIP1

461

Q9H074
NFCDFRSRDDDYETI

NPY1R

336

P25929
DLEDRDCKYDYVEVF

NRP1

76

O14786
YLEDCKFDRERIELF

COMMD3

86

Q9UBI1
KFDRERIELFCTEYQ

COMMD3

91

Q9UBI1
YEVFRCEDSLDERKI

IFI44

146

Q8TCB0
FCTRPVDREEYDVFD

DSC3

196

Q14574
RKEDVYSCFRFLRDV

GNPAT

506

O15228
ETDREVEYFKRFCLD

FAM193B

861

Q96PV7
EDFDREFRCLYAESQ

FAM83C

291

Q9BQN1
KLRCERFVEELESYA

DNAH7

686

Q8WXX0
KFIREEDQCIFEHRY

GPR173

166

Q9NS66
EEKEVCRLEYRFGEF

HGSNAT

146

Q68CP4
RKCISYRFDEFDEAI

RSF1

1016

Q96T23
RLDRSEKETVAYFCA

INPP5F

346

Q9Y2H2
RRCKYFDTNSEVEEE

MIER1

151

Q8N108
DEDVIKVSDRCDYVF

TMEM132D

476

Q14C87
FRDEEGKEYVRCETV

TAF1

1171

P21675
LKELDECYERFSRET

ING1

191

Q9UK53
VYRFCDVKDETYDLL

PRSS23

291

O95084
RAEKECKIEYDDFVE

NDUFS5

51

O43920
AYKRLSTIFEECDEE

KIAA1217

1456

Q5T5P2
DSAFERKNITEYCRD

RECQL

481

P46063
GEFYECEDERIYTLK

THEMIS

171

Q8N1K5
RRDYVFIEFCVEDSK

PTGES3

11

Q15185
TDITEEDFKRLFERY

PSPC1

91

Q8WXF1
EQCIEEYFREKDDRF

TRPM3

1221

Q9HCF6
AIGVFTECYRKDEER

TRPM2

686

O94759
YDFCARDRSELSLKE

VAV1

791

P15498
EDDDLFETEFRQYKR

XRN1

421

Q8IZH2
TQRYRLEALKFCEEF

XPO5

26

Q9HAV4
RKEDQSVYFCRVELD

PILRB

116

Q9UKJ0
KSEEELAECFRIFDR

TNNC2

91

P02585
DLFFRAEELEYSCEK

USP37

526

Q86T82
CYIRFIDYDCRDVKE

ZMYM6

926

O95789
FEVEFDDRCETEKRY

ZZEF1

1121

O43149
DDRCETEKRYDYLEF

ZZEF1

1126

O43149
KDCEVDFVEYVRSLA

S100A3

66

P33764
CASDKILEFDRDFRI

MYO1D

491

O94832