Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionsodium channel activity

PKD2L1 GRIK1 GRIK2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

2.07e-11521199GO:0005272
GeneOntologyMolecularFunctiontransporter activity

CEACAM5 ABCA13 PIEZO1 FLVCR1 CEACAM8 SLC19A3 CEACAM6 PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ ATP13A2 SFXN1 SLC17A5 SCN4A SCN5A SFXN3 PKD2 SLC28A2 SCNN1B SFXN2 OSBPL10 TRPM8 CACNA1H CACNA1G GRAMD1C

3.36e-10128911929GO:0005215
GeneOntologyMolecularFunctionsodium ion transmembrane transporter activity

PKD2L1 SLC6A15 GRIK1 GRIK2 SLC13A2 SCN4A SCN5A PKD2 SLC28A2 SCNN1B CACNA1H CACNA1G

4.53e-1017111912GO:0015081
GeneOntologyMolecularFunctiontransmembrane transporter activity

CEACAM5 ABCA13 PIEZO1 FLVCR1 CEACAM8 SLC19A3 CEACAM6 PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ ATP13A2 SFXN1 SLC17A5 SCN4A SCN5A SFXN3 PKD2 SLC28A2 SCNN1B SFXN2 TRPM8 CACNA1H CACNA1G

1.09e-09118011927GO:0022857
GeneOntologyMolecularFunctionmonoatomic ion transmembrane transporter activity

PIEZO1 PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ ATP13A2 SFXN1 SLC17A5 SCN4A SCN5A SFXN3 PKD2 SLC28A2 SCNN1B SFXN2 TRPM8 CACNA1H CACNA1G

8.53e-0979311921GO:0015075
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

CEACAM5 CEACAM8 SLC19A3 CEACAM6 SLC6A15 GRIK1 GRIK2 SLC13A2 SFXN1 SLC17A5 SFXN3

4.52e-0820711911GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

CEACAM5 CEACAM8 SLC19A3 CEACAM6 SLC6A15 GRIK1 GRIK2 SLC13A2 SFXN1 SLC17A5 SFXN3

4.75e-0820811911GO:0005342
GeneOntologyMolecularFunctionmonoatomic cation transmembrane transporter activity

PIEZO1 PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ ATP13A2 SLC17A5 SCN4A SCN5A PKD2 SLC28A2 SCNN1B TRPM8 CACNA1H CACNA1G

7.90e-0866411918GO:0008324
GeneOntologyMolecularFunctionmetal ion transmembrane transporter activity

PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ SCN4A SCN5A PKD2 SLC28A2 SCNN1B TRPM8 CACNA1H CACNA1G

1.16e-0746511915GO:0046873
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

CEACAM5 CEACAM8 SLC19A3 CEACAM6 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 SFXN1 SLC17A5 SFXN3

1.87e-0729311912GO:0008514
GeneOntologyMolecularFunctionvoltage-gated sodium channel activity

SCN4A SCN5A PKD2 CACNA1H CACNA1G

4.11e-07261195GO:0005248
GeneOntologyMolecularFunctioninorganic cation transmembrane transporter activity

PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ SLC17A5 SCN4A SCN5A PKD2 SLC28A2 SCNN1B TRPM8 CACNA1H CACNA1G

9.91e-0762711916GO:0022890
GeneOntologyMolecularFunctionmonoatomic cation channel activity

PIEZO1 PKD2L1 GRIK1 GRIK2 PKDREJ SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

9.97e-0734311912GO:0005261
GeneOntologyMolecularFunctioninorganic molecular entity transmembrane transporter activity

PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 SLC13A2 PKDREJ SLC17A5 SCN4A SCN5A PKD2 SLC28A2 SCNN1B TRPM8 CACNA1H CACNA1G

1.11e-0575811916GO:0015318
GeneOntologyMolecularFunctioncalcium channel activity

PKD2L1 GRIK1 PKDREJ PKD2 TRPM8 CACNA1H CACNA1G

1.23e-051291197GO:0005262
GeneOntologyMolecularFunctionmonoatomic ion channel activity

PIEZO1 PKD2L1 GRIK1 GRIK2 PKDREJ SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

1.94e-0545911912GO:0005216
GeneOntologyMolecularFunctioncalcium ion transmembrane transporter activity

PKD2L1 GRIK1 PKDREJ PKD2 TRPM8 CACNA1H CACNA1G

3.40e-051511197GO:0015085
GeneOntologyMolecularFunctionchannel activity

PIEZO1 PKD2L1 GRIK1 GRIK2 PKDREJ SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

7.12e-0552511912GO:0015267
GeneOntologyMolecularFunctionpassive transmembrane transporter activity

PIEZO1 PKD2L1 GRIK1 GRIK2 PKDREJ SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

7.25e-0552611912GO:0022803
GeneOntologyMolecularFunctionlow voltage-gated calcium channel activity

CACNA1H CACNA1G

1.05e-0431192GO:0008332
GeneOntologyMolecularFunctionligand-gated sodium channel activity

GRIK1 GRIK2 SCNN1B

1.58e-04181193GO:0015280
GeneOntologyMolecularFunctionminus-end-directed microtubule motor activity

DNAH14 DNAH1 DNAH6

1.58e-04181193GO:0008569
GeneOntologyMolecularFunctiongated channel activity

PIEZO1 PKD2L1 GRIK1 GRIK2 PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

1.77e-043341199GO:0022836
GeneOntologyMolecularFunctionligand-gated monoatomic cation channel activity

PKD2L1 GRIK1 GRIK2 PKD2 SCNN1B TRPM8

1.93e-041401196GO:0099094
GeneOntologyMolecularFunctionscaffold protein binding

GRIK1 GRIK2 SCN5A CACNA1H CACNA1G

2.36e-04931195GO:0097110
GeneOntologyMolecularFunctionGPI anchor binding

CEACAM5 CEACAM8 CEACAM6

3.35e-04231193GO:0034235
GeneOntologyMolecularFunctionamino acid transmembrane transporter activity

SLC6A15 GRIK1 GRIK2 SFXN1 SFXN3

4.15e-041051195GO:0015171
GeneOntologyMolecularFunctionkainate selective glutamate receptor activity

GRIK1 GRIK2

5.20e-0461192GO:0015277
GeneOntologyMolecularFunctiondynein light intermediate chain binding

DNAH14 DNAH1 DNAH6

6.06e-04281193GO:0051959
GeneOntologyMolecularFunctionfilamin binding

CEACAM5 CEACAM8 CEACAM6

6.73e-04291193GO:0031005
GeneOntologyMolecularFunctionextracellularly glutamate-gated ion channel activity

GRIK1 GRIK2

7.25e-0471192GO:0005234
GeneOntologyMolecularFunctionsolute:monoatomic cation symporter activity

SLC6A15 SLC39A10 SLC13A2 SLC17A5 SLC28A2

7.35e-041191195GO:0015294
GeneOntologyMolecularFunctionalpha-actinin binding

PKD2L1 ADORA2A PKD2

8.21e-04311193GO:0051393
GeneOntologyMolecularFunctionligand-gated calcium channel activity

GRIK1 PKD2 TRPM8

8.21e-04311193GO:0099604
GeneOntologyMolecularFunctiontaste receptor activity

PKD2L1 TAS2R8 TAS2R20

9.88e-04331193GO:0008527
GeneOntologyMolecularFunctionligand-gated monoatomic ion channel activity

PKD2L1 GRIK1 GRIK2 PKD2 SCNN1B TRPM8

1.06e-031931196GO:0015276
GeneOntologyMolecularFunctionbile acid transmembrane transporter activity

CEACAM5 CEACAM8 CEACAM6

1.08e-03341193GO:0015125
GeneOntologyMolecularFunctionlipid transporter activity

CEACAM5 ABCA13 CEACAM8 CEACAM6 OSBPL10 GRAMD1C

1.15e-031961196GO:0005319
GeneOntologyMolecularFunctionligand-gated channel activity

PKD2L1 GRIK1 GRIK2 PKD2 SCNN1B TRPM8

1.18e-031971196GO:0022834
GeneOntologyMolecularFunctionL-serine transmembrane transporter activity

SFXN1 SFXN3

1.23e-0391192GO:0015194
GeneOntologyMolecularFunctiondynein intermediate chain binding

DNAH14 DNAH1 DNAH6

1.38e-03371193GO:0045505
GeneOntologyMolecularFunctioninositol phosphate kinase activity

PPIP5K2 IPMK

1.87e-03111192GO:0180030
GeneOntologyMolecularFunctionsymporter activity

SLC6A15 SLC39A10 SLC13A2 SLC17A5 SLC28A2

2.06e-031501195GO:0015293
GeneOntologyMolecularFunctionactinin binding

PKD2L1 ADORA2A PKD2

2.14e-03431193GO:0042805
GeneOntologyMolecularFunctionvoltage-gated calcium channel activity

PKD2 CACNA1H CACNA1G

2.60e-03461193GO:0005245
GeneOntologyMolecularFunctionazole transmembrane transporter activity

SLC19A3 SLC28A2

3.06e-03141192GO:1901474
GeneOntologyMolecularFunctiongranulocyte colony-stimulating factor receptor binding

CEACAM5 CEACAM6

3.06e-03141192GO:0005130
GeneOntologyMolecularFunctionhigh voltage-gated calcium channel activity

CACNA1H CACNA1G

3.06e-03141192GO:0008331
GeneOntologyMolecularFunctionglycolipid binding

CEACAM5 CEACAM8 CEACAM6

3.11e-03491193GO:0051861
GeneOntologyMolecularFunctionmuscle alpha-actinin binding

PKD2L1 PKD2

3.52e-03151192GO:0051371
GeneOntologyMolecularFunctionheparan sulfate sulfotransferase activity

NDST4 HS3ST5

3.52e-03151192GO:0034483
GeneOntologyMolecularFunctionglutamate-gated receptor activity

GRIK1 GRIK2

4.52e-03171192GO:0004970
GeneOntologyMolecularFunctionphospholipid binding

BIN1 CEACAM5 CEACAM8 CEACAM6 ATP13A2 NF1 SBF2 OSBPL10 VPS13B

5.55e-035481199GO:0005543
GeneOntologyMolecularFunctionlipid binding

BIN1 CEACAM5 CEACAM8 CEACAM6 ATP13A2 ADORA2A NF1 SBF2 OSBPL11 OSBPL10 DMBT1 GRAMD1C VPS13B

6.02e-0398811913GO:0008289
GeneOntologyBiologicalProcesscarboxylic acid transport

HNF1A CEACAM5 CEACAM8 SLC19A3 CEACAM6 SLC6A15 GRIK1 SLC13A2 SFXN1 ADORA2A SLC17A5 NF1 SFXN3 SFXN2

1.19e-0741012014GO:0046942
GeneOntologyBiologicalProcessorganic acid transport

HNF1A CEACAM5 CEACAM8 SLC19A3 CEACAM6 SLC6A15 GRIK1 SLC13A2 SFXN1 ADORA2A SLC17A5 NF1 SFXN3 SFXN2

1.26e-0741212014GO:0015849
GeneOntologyBiologicalProcessserine import into mitochondrion

SFXN1 SFXN3 SFXN2

1.92e-0731203GO:0140300
GeneOntologyBiologicalProcessmonoatomic ion transport

BIN1 PIEZO1 FLVCR1 PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 TMBIM6 SLC13A2 PKDREJ ATP13A2 SFXN1 ADORA2A SLC17A5 SCN4A SCN5A SFXN3 PKD2 SCNN1B SFXN2 TRPM8 CACNA1H CACNA1G CTNNB1

2.80e-07137412025GO:0006811
GeneOntologyBiologicalProcessorganic anion transport

HNF1A CEACAM5 CEACAM8 SLC19A3 CEACAM6 SLC6A15 GRIK1 SLC39A10 SLC13A2 SFXN1 ADORA2A SLC17A5 NF1 SFXN3 SFXN2

3.18e-0751512015GO:0015711
GeneOntologyBiologicalProcesssodium ion transmembrane transport

PKD2L1 SLC6A15 GRIK1 SLC13A2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

3.88e-0720812010GO:0035725
GeneOntologyBiologicalProcessmonoatomic ion transmembrane transport

BIN1 PIEZO1 PKD2L1 SLC6A15 GRIK1 GRIK2 SLC39A10 TMBIM6 SLC13A2 PKDREJ ATP13A2 SFXN1 SLC17A5 SCN4A SCN5A SFXN3 PKD2 SCNN1B SFXN2 TRPM8 CACNA1H CACNA1G

4.26e-07111512022GO:0034220
GeneOntologyBiologicalProcessmonoatomic cation transport

BIN1 PIEZO1 FLVCR1 PKD2L1 SLC6A15 GRIK1 SLC39A10 TMBIM6 SLC13A2 PKDREJ ATP13A2 SFXN1 ADORA2A SLC17A5 SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G CTNNB1

7.93e-07115712022GO:0006812
GeneOntologyBiologicalProcessanatomical structure homeostasis

HNF1A CEACAM5 CEACAM6 PIWIL4 EXT1 ADGRV1 ADORA2A NF1 SLC28A2 CTNNB1 VPS13B

4.11e-0633412011GO:0060249
GeneOntologyBiologicalProcesstissue homeostasis

HNF1A CEACAM5 CEACAM6 PIWIL4 EXT1 ADGRV1 ADORA2A NF1 SLC28A2 CTNNB1 VPS13B

4.11e-0633412011GO:0001894
GeneOntologyBiologicalProcesssodium ion transport

PKD2L1 SLC6A15 GRIK1 SLC13A2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

4.82e-0627512010GO:0006814
GeneOntologyBiologicalProcessdetection of mechanical stimulus

PIEZO1 PKD2L1 ADGRV1 PKDREJ PKD2 CTNNB1

4.96e-06751206GO:0050982
GeneOntologyBiologicalProcessmetal ion transport

BIN1 FLVCR1 PKD2L1 SLC6A15 GRIK1 SLC39A10 TMBIM6 SLC13A2 PKDREJ SFXN1 ADORA2A SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G CTNNB1

5.02e-06100012019GO:0030001
GeneOntologyBiologicalProcessmonoatomic cation transmembrane transport

BIN1 PIEZO1 PKD2L1 SLC6A15 GRIK1 SLC39A10 TMBIM6 SLC13A2 PKDREJ ATP13A2 SLC17A5 SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

8.49e-0694212018GO:0098655
GeneOntologyBiologicalProcessmulticellular organismal-level homeostasis

HNF1A CEACAM5 NRDC FLVCR1 CEACAM8 CEACAM6 PIWIL4 EXT1 ADGRV1 SFXN1 ADORA2A NF1 JMJD6 LPCAT3 SLC28A2 SCNN1B TRPM8 CTNNB1 VPS13B

9.14e-06104312019GO:0048871
GeneOntologyBiologicalProcessamino acid transport

SLC6A15 GRIK1 SFXN1 ADORA2A SLC17A5 NF1 SFXN3 SFXN2

1.88e-051951208GO:0006865
GeneOntologyBiologicalProcessorganic cation transport

SLC19A3 SLC6A15 SFXN1 ADORA2A SCN4A SFXN3 SFXN2

2.25e-051451207GO:0015695
GeneOntologyBiologicalProcessbone resorption

HNF1A CEACAM5 CEACAM6 EXT1 NF1 CTNNB1

2.47e-05991206GO:0045453
GeneOntologyBiologicalProcessserine transport

SFXN1 SFXN3 SFXN2

3.06e-05111203GO:0032329
GeneOntologyBiologicalProcessneuronal action potential

GRIK2 SCN4A SCN5A CACNA1H CACNA1G

3.29e-05631205GO:0019228
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process

NDST4 HS3ST5 EXT1 CTNNB1

4.96e-05351204GO:0015012
GeneOntologyBiologicalProcessmembrane depolarization during action potential

SCN4A SCN5A CACNA1H CACNA1G

5.56e-05361204GO:0086010
GeneOntologyBiologicalProcessnegative regulation of brown fat cell proliferation

CEACAM5 CEACAM8 CEACAM6

6.67e-05141203GO:0070348
GeneOntologyBiologicalProcessdetection of external stimulus

PIEZO1 PKD2L1 GRIK2 ADGRV1 PKDREJ PKD2 CTNNB1

6.94e-051731207GO:0009581
GeneOntologyBiologicalProcessdetection of abiotic stimulus

PIEZO1 PKD2L1 GRIK2 ADGRV1 PKDREJ PKD2 CTNNB1

7.46e-051751207GO:0009582
GeneOntologyBiologicalProcessmembrane depolarization

GRIK1 ADORA2A SCN4A SCN5A CACNA1H CACNA1G

7.62e-051211206GO:0051899
GeneOntologyBiologicalProcessregulation of brown fat cell proliferation

CEACAM5 CEACAM8 CEACAM6

8.30e-05151203GO:0070347
GeneOntologyBiologicalProcesspositive regulation of homophilic cell adhesion

CEACAM5 CEACAM8 CEACAM6

8.30e-05151203GO:1903387
GeneOntologyBiologicalProcessinorganic cation transmembrane transport

BIN1 PKD2L1 SLC6A15 GRIK1 SLC39A10 TMBIM6 SLC13A2 PKDREJ SLC17A5 SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

8.86e-0592212016GO:0098662
GeneOntologyBiologicalProcessbone remodeling

HNF1A CEACAM5 CEACAM6 EXT1 NF1 CTNNB1

9.97e-051271206GO:0046849
GeneOntologyBiologicalProcessinsulin receptor internalization

CEACAM5 CEACAM8 CEACAM6

1.02e-04161203GO:0038016
GeneOntologyBiologicalProcessbrown fat cell proliferation

CEACAM5 CEACAM8 CEACAM6

1.23e-04171203GO:0070342
GeneOntologyBiologicalProcessinsulin catabolic process

CEACAM5 CEACAM8 CEACAM6

1.23e-04171203GO:1901143
GeneOntologyBiologicalProcessregulation of homophilic cell adhesion

CEACAM5 CEACAM8 CEACAM6

1.47e-04181203GO:1903385
GeneOntologyBiologicalProcessbile acid and bile salt transport

HNF1A CEACAM5 CEACAM8 CEACAM6

1.60e-04471204GO:0015721
GeneOntologyBiologicalProcessnegative regulation of anoikis

CEACAM5 CEACAM6 ITGA5

1.74e-04191203GO:2000811
GeneOntologyBiologicalProcessnegative regulation of hepatocyte proliferation

CEACAM5 CEACAM8 CEACAM6

2.04e-04201203GO:2000346
GeneOntologyBiologicalProcesscardiac muscle cell contraction

BIN1 SCN4A SCN5A CACNA1H CACNA1G

2.12e-04931205GO:0086003
GeneOntologyBiologicalProcessnegative regulation of fat cell proliferation

CEACAM5 CEACAM8 CEACAM6

2.37e-04211203GO:0070345
GeneOntologyBiologicalProcessinorganic ion transmembrane transport

BIN1 PKD2L1 SLC6A15 GRIK1 SLC39A10 TMBIM6 SLC13A2 PKDREJ SLC17A5 SCN4A SCN5A PKD2 SCNN1B TRPM8 CACNA1H CACNA1G

2.71e-04101712016GO:0098660
GeneOntologyBiologicalProcessmembrane depolarization during SA node cell action potential

SCN5A CACNA1G

3.32e-0451202GO:0086046
GeneOntologyBiologicalProcesscarboxylic acid transmembrane transport

SLC6A15 SLC13A2 SFXN1 SLC17A5 SFXN3 SFXN2

3.86e-041631206GO:1905039
GeneOntologyBiologicalProcessnegative regulation of osteoclast differentiation

CEACAM5 CEACAM6 NF1 CTNNB1

3.87e-04591204GO:0045671
GeneOntologyBiologicalProcessneutral amino acid transport

SLC6A15 SFXN1 SFXN3 SFXN2

4.13e-04601204GO:0015804
GeneOntologyBiologicalProcessorganic acid transmembrane transport

SLC6A15 SLC13A2 SFXN1 SLC17A5 SFXN3 SFXN2

4.39e-041671206GO:1903825
GeneOntologyBiologicalProcessregulation of anoikis

CEACAM5 CEACAM6 ITGA5

4.53e-04261203GO:2000209
GeneOntologyBiologicalProcesscardiac muscle cell action potential involved in contraction

BIN1 SCN4A SCN5A CACNA1G

4.68e-04621204GO:0086002
GeneOntologyBiologicalProcessimport into cell

DOCK1 BIN1 CEACAM5 ABCA13 CEACAM8 CEACAM6 SLC39A10 ADORA2A VAC14 JMJD6 MRC2 SCN5A SCNN1B CACNA1H CACNA1G DMBT1

4.95e-04107412016GO:0098657
GeneOntologyBiologicalProcessmembrane depolarization during AV node cell action potential

SCN5A CACNA1G

4.96e-0461202GO:0086045
GeneOntologyBiologicalProcessheterophilic cell-cell adhesion via plasma membrane cell adhesion molecules

CEACAM5 CEACAM8 CEACAM6 ITGA5

4.98e-04631204GO:0007157
GeneOntologyBiologicalProcesstransmission of nerve impulse

GRIK2 SCN4A SCN5A CACNA1H CACNA1G

5.01e-041121205GO:0019226
GeneOntologyBiologicalProcessregulation of fat cell proliferation

CEACAM5 CEACAM8 CEACAM6

5.07e-04271203GO:0070344
GeneOntologyBiologicalProcessinhibitory postsynaptic potential

GRIK1 GRIK2 ADORA2A

5.07e-04271203GO:0060080
GeneOntologyBiologicalProcessamino acid transmembrane transport

SLC6A15 GRIK1 SFXN1 SFXN3 SFXN2

6.86e-041201205GO:0003333
GeneOntologyBiologicalProcessalcohol metabolic process

HNF1A MBTPS1 OCRL LPCAT3 SCNN1B CACNA1H ALDH1B1 PPIP5K2 IPMK

6.89e-044121209GO:0006066
GeneOntologyBiologicalProcesslimb joint morphogenesis

EXT1 CTNNB1

6.92e-0471202GO:0036022
GeneOntologyBiologicalProcesssensory perception of taste

PKD2L1 TAS2R8 SCNN1B TAS2R20

7.43e-04701204GO:0050909
GeneOntologyBiologicalProcessproteoglycan biosynthetic process

NDST4 HS3ST5 EXT1 CTNNB1

7.43e-04701204GO:0030166
GeneOntologyBiologicalProcesslipid transport

HNF1A CEACAM5 ABCA13 CEACAM8 CEACAM6 LPCAT3 OSBPL11 OSBPL10 GRAMD1C VPS13B

7.54e-0450612010GO:0006869
GeneOntologyBiologicalProcesscalcium ion transport

BIN1 PKD2L1 TMBIM6 PKDREJ ADORA2A PKD2 TRPM8 CACNA1H CACNA1G CTNNB1

7.89e-0450912010GO:0006816
GeneOntologyBiologicalProcessfat cell proliferation

CEACAM5 CEACAM8 CEACAM6

8.42e-04321203GO:0070341
GeneOntologyBiologicalProcesstissue remodeling

HNF1A CEACAM5 CEACAM6 EXT1 NF1 CELA1 CTNNB1

8.66e-042621207GO:0048771
GeneOntologyBiologicalProcessactin-mediated cell contraction

BIN1 SCN4A SCN5A CACNA1H CACNA1G

8.86e-041271205GO:0070252
GeneOntologyBiologicalProcessheparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process

NDST4 EXT1

9.19e-0481202GO:0015014
GeneOntologyBiologicalProcessnegative regulation of feeding behavior

CEACAM5 CEACAM8 CEACAM6

9.22e-04331203GO:2000252
GeneOntologyBiologicalProcessnegative regulation of vascular permeability

CEACAM5 CEACAM6 ADORA2A

1.01e-03341203GO:0043116
GeneOntologyBiologicalProcessinorganic ion homeostasis

FLVCR1 GRIK2 EXT1 SLC39A10 TMBIM6 ATP13A2 THADA PKD2 PKHD1 SCNN1B TRPM8

1.02e-0362212011GO:0098771
GeneOntologyBiologicalProcesssynaptic transmission, glutamatergic

GRIK1 GRIK2 EXT1 ADORA2A NF1

1.05e-031321205GO:0035249
GeneOntologyBiologicalProcessinsulin metabolic process

CEACAM5 CEACAM8 CEACAM6

1.10e-03351203GO:1901142
GeneOntologyBiologicalProcessaction potential

BIN1 GRIK2 SCN4A SCN5A CACNA1H CACNA1G

1.16e-032011206GO:0001508
GeneOntologyBiologicalProcesscirculatory system process

BIN1 CEACAM5 CEACAM6 EXT1 F5 ADORA2A SCN4A SCN5A SLC28A2 SCNN1B CACNA1H CACNA1G

1.17e-0373312012GO:0003013
GeneOntologyBiologicalProcessphosphatidylserine acyl-chain remodeling

LPCAT3 OSBPL10

1.18e-0391202GO:0036150
GeneOntologyBiologicalProcessthermoception

GRIK2 TRPM8

1.18e-0391202GO:0050955
GeneOntologyBiologicalProcesssensory perception of sour taste

PKD2L1 SCNN1B

1.18e-0391202GO:0050915
GeneOntologyBiologicalProcessL-serine transport

SFXN1 SFXN3

1.18e-0391202GO:0015825
GeneOntologyBiologicalProcessorganic hydroxy compound transport

HNF1A CEACAM5 ABCA13 CEACAM8 SLC19A3 CEACAM6 ADORA2A GRAMD1C

1.19e-033581208GO:0015850
GeneOntologyBiologicalProcessliver development

HNF1A CEACAM5 CEACAM8 CEACAM6 NF1 PKD2

1.19e-032021206GO:0001889
GeneOntologyBiologicalProcesshepaticobiliary system development

HNF1A CEACAM5 CEACAM8 CEACAM6 NF1 PKD2

1.28e-032051206GO:0061008
GeneOntologyBiologicalProcessanoikis

CEACAM5 CEACAM6 ITGA5

1.29e-03371203GO:0043276
GeneOntologyBiologicalProcessregulation of hepatocyte proliferation

CEACAM5 CEACAM8 CEACAM6

1.40e-03381203GO:2000345
GeneOntologyBiologicalProcessblood circulation

BIN1 CEACAM5 CEACAM6 EXT1 F5 ADORA2A SCN4A SCN5A SCNN1B CACNA1H CACNA1G

1.42e-0364812011GO:0008015
GeneOntologyBiologicalProcessinorganic ion import across plasma membrane

SLC39A10 SCN5A SCNN1B CACNA1H CACNA1G

1.46e-031421205GO:0099587
GeneOntologyBiologicalProcessinorganic cation import across plasma membrane

SLC39A10 SCN5A SCNN1B CACNA1H CACNA1G

1.46e-031421205GO:0098659
GeneOntologyBiologicalProcessregulation of atrial cardiac muscle cell membrane depolarization

SCN5A CACNA1G

1.47e-03101202GO:0060371
GeneOntologyBiologicalProcessSA node cell to atrial cardiac muscle cell signaling

SCN5A CACNA1G

1.47e-03101202GO:0086018
GeneOntologyBiologicalProcessSA node cell action potential

SCN5A CACNA1G

1.47e-03101202GO:0086015
GeneOntologyCellularComponentsodium channel complex

GRIK1 GRIK2 SCN4A SCN5A SCNN1B CACNA1H CACNA1G

2.57e-10291217GO:0034706
GeneOntologyCellularComponentcation channel complex

CATSPERE PKD2L1 GRIK1 GRIK2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

1.13e-0623512110GO:0034703
GeneOntologyCellularComponentvoltage-gated sodium channel complex

SCN4A SCN5A CACNA1H CACNA1G

2.40e-06171214GO:0001518
GeneOntologyCellularComponentmonoatomic ion channel complex

CATSPERE PKD2L1 GRIK1 GRIK2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

7.08e-0537812110GO:0034702
GeneOntologyCellularComponenttransforming growth factor beta ligand-receptor complex

CEACAM5 CEACAM8 CEACAM6

1.00e-04161213GO:0070021
GeneOntologyCellularComponentlateral plasma membrane

CEACAM5 CEACAM8 CEACAM6 SCN5A CTNNB1

1.77e-04901215GO:0016328
GeneOntologyCellularComponentcell projection membrane

CEACAM5 PIEZO1 CEACAM6 PKD2L1 ADGRV1 ITGA5 ADORA2A PKD2 SLC28A2 CTNNB1

2.07e-0443112110GO:0031253
GeneOntologyCellularComponentvesicle membrane

BIN1 ABCA13 CEACAM8 CEACAM6 VPS25 OCRL ATP13A2 SLC17A5 VAC14 PTPRB ANTXR2 SBF2 PKD2 SLC28A2 SCNN1B OSBPL11 DMBT1 VPS13B SYNGR4

2.15e-04132512119GO:0012506
GeneOntologyCellularComponentkainate selective glutamate receptor complex

GRIK1 GRIK2

4.91e-0461212GO:0032983
GeneOntologyCellularComponentcytoplasmic vesicle membrane

BIN1 ABCA13 CEACAM8 CEACAM6 VPS25 OCRL ATP13A2 SLC17A5 VAC14 PTPRB ANTXR2 SBF2 PKD2 SCNN1B OSBPL11 DMBT1 VPS13B SYNGR4

5.20e-04130712118GO:0030659
GeneOntologyCellularComponentplasma membrane protein complex

CATSPERE CEACAM5 CEACAM8 CEACAM6 GRIK1 GRIK2 ITGA5 TRBV9 SCN4A SCN5A CACNA1H CACNA1G CTNNB1

6.28e-0478512113GO:0098797
GeneOntologyCellularComponentcilium

HNF1A CATSPERE CEACAM5 CEACAM6 PKD2L1 OCRL ADGRV1 DNAH14 DNAH1 RSPH10B2 PKD2 PKHD1 TAS2R20 DNAH6

6.99e-0489812114GO:0005929
GeneOntologyCellularComponentcalcium channel complex

CATSPERE PKD2L1 CACNA1H CACNA1G

8.54e-04731214GO:0034704
GeneOntologyCellularComponentglutamatergic synapse

DOCK1 BIN1 GRIK1 GRIK2 ITGA5 CSMD2 ADORA2A SLC17A5 NF1 CASKIN1 CACNA1H PARN CTNNB1

9.07e-0481712113GO:0098978
GeneOntologyCellularComponenttransmembrane transporter complex

CATSPERE PKD2L1 GRIK1 GRIK2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

9.34e-0452312110GO:1902495
GeneOntologyCellularComponentnon-motile cilium

HNF1A PKD2L1 OCRL ADGRV1 PKD2 PKHD1

9.90e-041961216GO:0097730
GeneOntologyCellularComponenttransporter complex

CATSPERE PKD2L1 GRIK1 GRIK2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

1.36e-0355012110GO:1990351
GeneOntologyCellularComponentinner dynein arm

DNAH1 DNAH6

1.45e-03101212GO:0036156
GeneOntologyCellularComponentcell surface

CEACAM5 NRDC CEACAM8 MUC16 CEACAM6 PKD2L1 ADGRV1 ITGA5 VWDE ANTXR2 MRC2 SCN5A PKHD1 SCNN1B TRPM8

1.90e-03111112115GO:0009986
GeneOntologyCellularComponentreceptor complex

CEACAM5 CEACAM8 CEACAM6 PKD2L1 GRIK1 GRIK2 ADGRV1 ITGA5 PTPRB TRBV9

2.04e-0358112110GO:0043235
GeneOntologyCellularComponentvoltage-gated calcium channel complex

CATSPERE CACNA1H CACNA1G

2.40e-03461213GO:0005891
GeneOntologyCellularComponentmembrane protein complex

CATSPERE CEACAM5 CEACAM8 CEACAM6 PKD2L1 GRIK1 GRIK2 VPS25 ITGA5 VAC14 TRBV9 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G CTNNB1

2.43e-03149812118GO:0098796
GeneOntologyCellularComponentpostsynaptic membrane

GRIK1 GRIK2 ITGA5 CSMD2 ELFN2 ADORA2A CACNA1H CTNNB1

2.49e-034051218GO:0045211
GeneOntologyCellularComponentciliary membrane

CEACAM5 CEACAM6 PKD2L1 PKD2

2.54e-03981214GO:0060170
GeneOntologyCellularComponentGolgi membrane

MBTPS1 NDST4 HS3ST5 EXT1 RXYLT1 ZDHHC4 VAC14 GALNT11 COG5 PAQR3 VPS13B

3.13e-0372112111GO:0000139
DomainPKD_2

PKD2L1 PKDREJ PKD2

2.37e-0651173IPR003915
DomainMtc

SFXN1 SFXN3 SFXN2

2.37e-0651173PF03820
DomainMtc

SFXN1 SFXN3 SFXN2

2.37e-0651173IPR004686
DomainChannel_four-helix_dom

SCN4A SCN5A PKD2 CACNA1H CACNA1G

2.86e-05571175IPR027359
Domain-

SCN4A SCN5A PKD2 CACNA1H CACNA1G

2.86e-055711751.20.120.350
DomainPKD_channel

PKD2L1 PKDREJ PKD2

3.81e-05111173PF08016
DomainPKD1_2_channel

PKD2L1 PKDREJ PKD2

3.81e-05111173IPR013122
DomainDynein_heavy_chain_D4_dom

DNAH14 DNAH1 DNAH6

8.29e-05141173IPR024317
DomainDynein_HC_stalk

DNAH14 DNAH1 DNAH6

8.29e-05141173IPR024743
DomainSEA

TMPRSS15 MUC3B MUC16

8.29e-05141173SM00200
DomainMT

DNAH14 DNAH1 DNAH6

8.29e-05141173PF12777
DomainAAA_8

DNAH14 DNAH1 DNAH6

8.29e-05141173PF12780
DomainDHC_fam

DNAH14 DNAH1 DNAH6

1.03e-04151173IPR026983
DomainDynein_heavy

DNAH14 DNAH1 DNAH6

1.03e-04151173PF03028
DomainDynein_heavy_dom

DNAH14 DNAH1 DNAH6

1.03e-04151173IPR004273
DomainVDCC_T_a1

CACNA1H CACNA1G

1.16e-0431172IPR005445
DomainSEA

TMPRSS15 MUC3B MUC16

3.38e-04221173PF01390
DomainExostosin

EXT1 RXYLT1

3.84e-0451172PF03016
DomainExostosin

EXT1 RXYLT1

3.84e-0451172IPR004263
DomainSEA

TMPRSS15 MUC3B MUC16

3.87e-04231173PS50024
DomainSEA_dom

TMPRSS15 MUC3B MUC16

3.87e-04231173IPR000082
DomainEPTP

ADGRV1 LGI3

5.74e-0461172PF03736
DomainEPTP

ADGRV1 LGI3

5.74e-0461172IPR005492
DomainIon_trans_dom

SCN4A SCN5A TRPM8 CACNA1H CACNA1G

7.55e-041141175IPR005821
DomainIon_trans

SCN4A SCN5A TRPM8 CACNA1H CACNA1G

7.55e-041141175PF00520
DomainEAR

ADGRV1 LGI3

8.00e-0471172IPR009039
DomainEAR

ADGRV1 LGI3

8.00e-0471172PS50912
DomainNa_channel_asu

SCN4A SCN5A

1.69e-03101172IPR001696
DomainNa_trans_assoc

SCN4A SCN5A

1.69e-03101172IPR010526
DomainNa_trans_assoc

SCN4A SCN5A

1.69e-03101172PF06512
DomainVDCCAlpha1

CACNA1H CACNA1G

1.69e-03101172IPR002077
DomainOxysterol-bd_CS

OSBPL11 OSBPL10

2.46e-03121172IPR018494
DomainOxysterol_BP

OSBPL11 OSBPL10

2.46e-03121172PF01237
DomainOxysterol-bd

OSBPL11 OSBPL10

2.46e-03121172IPR000648
DomainOSBP

OSBPL11 OSBPL10

2.46e-03121172PS01013
DomainDynein_heavy_dom-2

DNAH1 DNAH6

3.37e-03141172IPR013602
DomainDHC_N2

DNAH1 DNAH6

3.37e-03141172PF08393
DomainATPase_dyneun-rel_AAA

DNAH1 DNAH6

3.37e-03141172IPR011704
DomainAAA_5

DNAH1 DNAH6

3.37e-03141172PF07728
DomainCUB

TMPRSS15 CSMD2 DMBT1

3.58e-03491173PF00431
DomainCUB

TMPRSS15 CSMD2 DMBT1

3.79e-03501173SM00042
Domain-

TMPRSS15 MUC16

3.87e-031511723.30.70.960
Domain-

TMPRSS15 CSMD2 DMBT1

4.24e-035211732.60.120.290
DomainGRAM

SBF2 GRAMD1C

4.41e-03161172SM00568
DomainPINT

PSMD13 EIF3M

4.41e-03161172SM00088
DomainCUB

TMPRSS15 CSMD2 DMBT1

4.47e-03531173PS01180
DomainPCI_dom

PSMD13 EIF3M

4.98e-03171172IPR000717
DomainPCI

PSMD13 EIF3M

4.98e-03171172PF01399
DomainCUB_dom

TMPRSS15 CSMD2 DMBT1

5.48e-03571173IPR000859
DomainARM-type_fold

DOCK1 STK36 VAC14 THADA NF1 CTNNB1 EIF3M

5.51e-033391177IPR016024
DomainLig_chan-Glu_bd

GRIK1 GRIK2

5.58e-03181172PF10613
DomainGlu/Gly-bd

GRIK1 GRIK2

5.58e-03181172IPR019594
DomainLig_chan-Glu_bd

GRIK1 GRIK2

5.58e-03181172SM00918
DomainIontro_rcpt

GRIK1 GRIK2

5.58e-03181172IPR001320
DomainIono_rcpt_met

GRIK1 GRIK2

5.58e-03181172IPR001508
DomainLig_chan

GRIK1 GRIK2

5.58e-03181172PF00060
DomainPBPe

GRIK1 GRIK2

5.58e-03181172SM00079
PathwayREACTOME_FIBRONECTIN_MATRIX_FORMATION

CEACAM8 CEACAM6 ITGA5

5.66e-066943M26970
Pubmed

Diverse oligomeric states of CEACAM IgV domains.

CEACAM5 CEACAM8 CEACAM6

1.76e-074124326483485
Pubmed

A co-clustering model involving alpha5beta1 integrin for the biological effects of GPI-anchored human carcinoembryonic antigen (CEA).

CEACAM5 CEACAM6 ITGA5

1.76e-074124317286276
Pubmed

Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.

DOCK1 MBTPS1 FLVCR1 GRIK1 GRIK2 ADGRV1 DNAH14 DNAH1 SFXN1 THADA PTPRB UBE2H GALNT11 LPCAT3 SBF2 SFXN3 PKD2 CACNA1H EIF3M VPS13B

3.23e-0714891242028611215
Pubmed

SFXN1 is a mitochondrial serine transporter required for one-carbon metabolism.

SFXN1 SFXN3 SFXN2

4.40e-075124330442778
Pubmed

Polycystin channels and kidney disease.

PKD2L1 PKDREJ PKD2

4.40e-075124311698076
Pubmed

Developmental waves of mechanosensitivity acquisition in sensory neuron subtypes during embryonic development.

PKD2L1 PKDREJ PKD2 SCNN1B TRPM8

5.16e-0744124519322198
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

MBTPS1 PIEZO1 SLC6A15 GRIK2 EXT1 RXYLT1 SLC39A10 ITGA5 VAC14 THADA LMF2 SERPINI1 NF1 MRC2 LPCAT3 PKD2 CTNNB1

1.34e-0612011241735696571
Pubmed

A mutation in a mitochondrial transmembrane protein is responsible for the pleiotropic hematological and skeletal phenotype of flexed-tail (f/f) mice.

SFXN1 SFXN3 SFXN2

2.45e-068124311274051
Pubmed

Two members of the TRPP family of ion channels, Pkd1l3 and Pkd2l1, are co-expressed in a subset of taste receptor cells.

PKD2L1 PKDREJ PKD2

5.21e-0610124316805797
Pubmed

Identification of a novel conserved human gene, TEGT.

ITGA5 TMBIM6 CELA1

5.21e-061012438530040
Pubmed

A quantitative analysis of the spatiotemporal pattern of transient receptor potential gene expression in the developing mouse cochlea.

PKD2L1 PKDREJ PKD2 TRPM8

5.81e-0633124419834762
Pubmed

Carcinoembryonic antigen (CEA)-related cell adhesion molecules are co-expressed in the human lung and their expression can be modulated in bronchial epithelial cells by non-typable Haemophilus influenzae, Moraxella catarrhalis, TLR3, and type I and II interferons.

CEACAM5 CEACAM6

1.26e-052124223941132
Pubmed

Altered behavioral responses to noxious stimuli and fear in glutamate receptor 5 (GluR5)- or GluR6-deficient mice.

GRIK1 GRIK2

1.26e-052124215673679
Pubmed

Precystectomy serum levels of carbohydrate antigen 19-9, carbohydrate antigen 125, and carcinoembryonic antigen: prognostic value in invasive urothelial carcinoma of the bladder.

CEACAM5 MUC16

1.26e-052124224680660
Pubmed

Cav3.2 subunit underlies the functional T-type Ca2+ channel in murine hearts during the embryonic period.

CACNA1H CACNA1G

1.26e-052124214988077
Pubmed

Role of T-type calcium channel subunits in post-myocardial infarction remodelling probed with genetically engineered mice.

CACNA1H CACNA1G

1.26e-052124221622683
Pubmed

Kainate receptors are involved in short- and long-term plasticity at mossy fiber synapses in the hippocampus.

GRIK1 GRIK2

1.26e-052124211182092
Pubmed

Piezo1-dependent stretch-activated channels are inhibited by Polycystin-2 in renal tubular epithelial cells.

PIEZO1 PKD2

1.26e-052124224157948
Pubmed

Modulation of excitatory synaptic transmission in the spinal substantia gelatinosa of mice deficient in the kainate receptor GluR5 and/or GluR6 subunit.

GRIK1 GRIK2

1.26e-052124214724198
Pubmed

The kainate receptor subunit GluR6 mediates metabotropic regulation of the slow and medium AHP currents in mouse hippocampal neurones.

GRIK1 GRIK2

1.26e-052124215539395
Pubmed

Ca(v)3.2 T-type Ca2+ channel-dependent activation of ERK in paraventricular thalamus modulates acid-induced chronic muscle pain.

CACNA1H CACNA1G

1.26e-052124220685979
Pubmed

Functional GluR6 kainate receptors in the striatum: indirect downregulation of synaptic transmission.

GRIK2 ADORA2A

1.26e-052124210704492
Pubmed

Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers.

CEACAM5 CEACAM6

1.26e-052124217201906
Pubmed

Differential recognition of members of the carcinoembryonic antigen family by Afa/Dr adhesins of diffusely adhering Escherichia coli (Afa/Dr DAEC).

CEACAM5 CEACAM6

1.26e-052124215130118
Pubmed

Expression of complementary DNA and genomic clones for carcinoembryonic antigen and nonspecific cross-reacting antigen in Chinese hamster ovary and mouse fibroblast cells and characterization of the membrane-expressed products.

CEACAM5 CEACAM6

1.26e-05212422317824
Pubmed

Biliary exosomes influence cholangiocyte regulatory mechanisms and proliferation through interaction with primary cilia.

PKD2 PKHD1

1.26e-052124220634433
Pubmed

RNA editing of human kainate receptor subunits.

GRIK1 GRIK2

1.26e-05212427696618
Pubmed

Fibrocystin/polyductin, found in the same protein complex with polycystin-2, regulates calcium responses in kidney epithelia.

PKD2 PKHD1

1.26e-052124217283055
Pubmed

Expression and novel subunit isoforms of glutamate receptor genes GluR5 and GluR6.

GRIK1 GRIK2

1.26e-05212428260617
Pubmed

Trajectories of Perioperative Serum Tumor Markers and Colorectal Cancer Outcomes: A Retrospective, Multicenter Longitudinal Cohort Study.

CEACAM5 MUC16

1.26e-052124234801967
Pubmed

Hydrophobic pore gates regulate ion permeation in polycystic kidney disease 2 and 2L1 channels.

PKD2L1 PKD2

1.26e-052124229899465
Pubmed

Carcinoembryonic antigen family: characterization of cDNAs coding for NCA and CEA and suggestion of nonrandom sequence variation in their conserved loop-domains.

CEACAM5 CEACAM6

1.26e-05212423220478
Pubmed

Genetic insights into fetal kidney development: Variants in HNF1A and PKHD1 genes.

HNF1A PKHD1

1.26e-052124238830515
Pubmed

High expression of carcinoembryonic antigen-related cell adhesion molecule (CEACAM) 6 and 8 in primary myelofibrosis.

CEACAM8 CEACAM6

1.26e-052124221470677
Pubmed

Assessing the role of GLUK5 and GLUK6 at hippocampal mossy fiber synapses.

GRIK1 GRIK2

1.26e-052124215537878
Pubmed

The influence of metastatic site on the expression of CEA and cellular localization of β-catenin in colorectal cancer.

CEACAM5 CTNNB1

1.26e-052124223216017
Pubmed

Chronic deficit in nitric oxide elicits oxidative stress and augments T-type calcium-channel contribution to vascular tone of rodent arteries and arterioles.

CACNA1H CACNA1G

1.26e-052124223436820
Pubmed

Mouse heart Na+ channels: primary structure and function of two isoforms and alternatively spliced variants.

SCN4A SCN5A

1.26e-052124211834499
Pubmed

Deficiency of T-type Ca2+ channels Cav3.1 and Cav3.2 has no effect on angiotensin II-induced hypertension but differential effect on plasma aldosterone in mice.

CACNA1H CACNA1G

1.26e-052124231042060
Pubmed

Identification of the structural motif responsible for trimeric assembly of the C-terminal regulatory domains of polycystin channels PKD2L1 and PKD2.

PKD2L1 PKD2

1.26e-052124220408813
Pubmed

Postnatal maturation of mossy fibre excitatory transmission in mouse CA3 pyramidal cells: a potential role for kainate receptors.

GRIK1 GRIK2

1.26e-052124215358807
Pubmed

Polycystin-2 expression is regulated by a PC2-binding domain in the intracellular portion of fibrocystin.

PKD2 PKHD1

1.26e-052124218782757
Pubmed

Role of GluK1 kainate receptors in seizures, epileptic discharges, and epileptogenesis.

GRIK1 GRIK2

1.26e-052124224760837
Pubmed

Preparation and characterization of two human carcinoembryonic antigen family proteins of neutrophils, CD66b and c, in silkworm larvae.

CEACAM8 CEACAM6

1.26e-05212428776764
Pubmed

An inhibitor of serine proteases, neuroserpin, acts as a neuroprotective agent in a mouse model of neurodegenerative disease.

SERPINI1 TBCE

1.26e-052124217035547
Pubmed

Phenotypic screen of sixty-eight colorectal cancer cell lines identifies CEACAM6 and CEACAM5 as markers of acid resistance.

CEACAM5 CEACAM6

1.26e-052124238502695
Pubmed

Co-expression of carcinoembryonic antigen-related cell adhesion molecule 6 and 8 inhibits proliferation and invasiveness of breast carcinoma cells.

CEACAM8 CEACAM6

1.26e-052124231222613
Pubmed

High expression of CEACAM6 and CEACAM8 mRNA in acute lymphoblastic leukemias.

CEACAM8 CEACAM6

1.26e-052124217909799
Pubmed

Identification of the kainate receptor subunits underlying modulation of excitatory synaptic transmission in the CA3 region of the hippocampus.

GRIK1 GRIK2

1.26e-052124211069933
Pubmed

Presynaptic kainate receptors impart an associative property to hippocampal mossy fiber long-term potentiation.

GRIK1 GRIK2

1.26e-052124212947409
Pubmed

Extracellular N-domain alone can mediate specific heterophilic adhesion between members of the carcinoembryonic antigen family, CEACAM6 and CEACAM8.

CEACAM8 CEACAM6

1.26e-052124211095950
Pubmed

Pharmacologically targeting beta-catenin for NF1 associated deficiencies in fracture repair.

NF1 CTNNB1

1.26e-052124228254468
Pubmed

Kainate receptor-mediated synaptic transmission in the adult anterior cingulate cortex.

GRIK1 GRIK2

1.26e-052124215928066
Pubmed

Cell adhesion activity of non-specific cross-reacting antigen (NCA) and carcinoembryonic antigen (CEA) expressed on CHO cell surface: homophilic and heterophilic adhesion.

CEACAM5 CEACAM6

1.26e-05212422803308
Pubmed

Q/R site editing in kainate receptor GluR5 and GluR6 pre-mRNAs requires distant intronic sequences.

GRIK1 GRIK2

1.26e-05212428700852
Pubmed

A specific heterotypic cell adhesion activity between members of carcinoembryonic antigen family, W272 and NCA, is mediated by N-domains.

CEACAM8 CEACAM6

1.26e-05212422022629
Pubmed

Q/R site editing controls kainate receptor inhibition by membrane fatty acids.

GRIK1 GRIK2

1.26e-052124216221857
Pubmed

Altered long-term synaptic plasticity and kainate-induced Ca2+ transients in the substantia gelatinosa neurons in GLU(K6)-deficient mice.

GRIK1 GRIK2

1.26e-052124216219388
Pubmed

Ca2+-dependent regulation of sodium channels NaV1.4 and NaV1.5 is controlled by the post-IQ motif.

SCN4A SCN5A

1.26e-052124230944319
Pubmed

T-type voltage-activated calcium channel Cav3.1, but not Cav3.2, is involved in the inhibition of proliferation and apoptosis in MCF-7 human breast cancer cells.

CACNA1H CACNA1G

1.26e-052124222469755
Pubmed

Subunit composition and alternative splicing regulate membrane delivery of kainate receptors.

GRIK1 GRIK2

1.26e-052124215014126
Pubmed

Dysregulation of the Scribble/YAP/β-catenin axis sustains the fibroinflammatory response in a PKHD1-/- mouse model of congenital hepatic fibrosis.

PKHD1 CTNNB1

1.26e-052124235593740
Pubmed

Subunit composition of kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

1.26e-052124211144357
Pubmed

Identification and comparison of residues critical for cell-adhesion activities of two neutrophil CD66 antigens, CEACAM6 and CEACAM8.

CEACAM8 CEACAM6

1.26e-052124211590190
Pubmed

Different distribution of Cav3.2 and Cav3.1 transcripts encoding T-type Ca(2+) channels in the embryonic heart of mice.

CACNA1H CACNA1G

1.26e-052124221079360
Pubmed

Human carcinoembryonic antigen functions as a general inhibitor of anoikis.

CEACAM5 CEACAM6

1.26e-052124210910050
Pubmed

Contribution of aberrant GluK2-containing kainate receptors to chronic seizures in temporal lobe epilepsy.

GRIK1 GRIK2

1.26e-052124225043179
Pubmed

The Ca(v)3.1 T-type calcium channel is required for neointimal formation in response to vascular injury in mice.

CACNA1H CACNA1G

1.26e-052124222886848
Pubmed

Molecular classification of hepatocellular adenoma in clinical practice.

HNF1A CTNNB1

1.26e-052124228733222
Pubmed

Significance of serum tumor marker levels in peritoneal carcinomatosis of appendiceal origin.

CEACAM5 MUC16

1.26e-052124222941175
Pubmed

A mosaic of functional kainate receptors in hippocampal interneurons.

GRIK1 GRIK2

1.26e-052124215483117
Pubmed

Deletion of T-type calcium channels Cav3.1 or Cav3.2 attenuates endothelial dysfunction in aging mice.

CACNA1H CACNA1G

1.26e-052124229082441
Pubmed

Truncating PKHD1 and PKD2 mutations alter energy metabolism.

PKD2 PKHD1

1.26e-052124230566001
Pubmed

Functional characterization of kainate receptors in the mouse nucleus accumbens.

GRIK1 GRIK2

1.26e-052124211985817
Pubmed

High-fat diet plus HNF1A variant promotes polyps by activating β-catenin in early-onset colorectal cancer.

HNF1A CTNNB1

1.26e-052124237219942
Pubmed

[Decreased mRNA expressions of T-type channel alpha1H and alpha1G in the sperm of varicocele patients and their implication].

CACNA1H CACNA1G

1.26e-052124222574369
Pubmed

Blockade of T-type Ca(2+) channels inhibits human ovarian cancer cell proliferation.

CACNA1H CACNA1G

1.26e-052124221438841
Pubmed

β-Adrenergic stimulation increases Cav3.1 activity in cardiac myocytes through protein kinase A.

CACNA1H CACNA1G

1.26e-052124222808078
Pubmed

Identification of N-linked glycoproteins in human saliva by glycoprotein capture and mass spectrometry.

CEACAM5 CEACAM8 CEACAM6 DMBT1

1.41e-0541124416740002
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 1 expression and signaling in human, mouse, and rat leukocytes: evidence for replacement of the short cytoplasmic domain isoform by glycosylphosphatidylinositol-linked proteins in human leukocytes.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124311994468
Pubmed

Carcinoembryonic antigen-related cell adhesion molecule 2 controls energy balance and peripheral insulin action in mice.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124320381490
Pubmed

Increased metabolic rate and insulin sensitivity in male mice lacking the carcino-embryonic antigen-related cell adhesion molecule 2.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124322159884
Pubmed

Age-dependent insulin resistance in male mice with null deletion of the carcinoembryonic antigen-related cell adhesion molecule 2 gene.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124328567513
Pubmed

Bgp2, a new member of the carcinoembryonic antigen-related gene family, encodes an alternative receptor for mouse hepatitis viruses.

CEACAM5 CEACAM8 CEACAM6

1.56e-051412438207827
Pubmed

CEACAM1 controls the EMT switch in murine mammary carcinoma in vitro and in vivo.

CEACAM5 CEACAM6 CTNNB1

1.56e-0514124327572314
Pubmed

CEACAM2 positively regulates integrin αIIbβ3-mediated platelet functions.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124327161904
Pubmed

Molecular cloning and localization of a CEACAM2 isoform, CEACAM2-L, expressed in spermatids in mouse testis.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124323070997
Pubmed

Comparison of expression patterns and cell adhesion properties of the mouse biliary glycoproteins Bbgp1 and Bbgp2.

CEACAM5 CEACAM8 CEACAM6

1.56e-0514124310491101
Pubmed

CEACAM2-L on spermatids interacts with poliovirus receptor on Sertoli cells in mouse seminiferous epithelium.

CEACAM5 CEACAM8 CEACAM6

1.95e-0515124324948196
Pubmed

Role of mouse hepatitis virus (MHV) receptor murine CEACAM1 in the resistance of mice to MHV infection: studies of mice with chimeric mCEACAM1a and mCEACAM1b.

CEACAM5 CEACAM8 CEACAM6

1.95e-0515124320410265
Pubmed

Increased Glucose-induced Secretion of Glucagon-like Peptide-1 in Mice Lacking the Carcinoembryonic Antigen-related Cell Adhesion Molecule 2 (CEACAM2).

CEACAM5 CEACAM8 CEACAM6

1.95e-0515124326586918
Pubmed

CEACAM2 negatively regulates hemi (ITAM-bearing) GPVI and CLEC-2 pathways and thrombus growth in vitro and in vivo.

CEACAM5 CEACAM8 CEACAM6

2.39e-0516124325085348
Pubmed

Differences in tissue-specific and embryonic expression of mouse Ceacam1 and Ceacam2 genes.

CEACAM5 CEACAM8 CEACAM6

2.39e-0516124311284729
Pubmed

Multiple mouse chromosomal loci for dynein-based motility.

DNAH14 DNAH1 NF1 DNAH6

2.44e-054712448812413
Pubmed

The transcription factor hepatocyte nuclear factor-6 controls the development of pancreatic ducts in the mouse.

PKD2 PKHD1 CTNNB1

2.90e-0517124316472605
Pubmed

5,6-EET potently inhibits T-type calcium channels: implication in the regulation of the vascular tone.

CACNA1H CACNA1G

3.77e-053124224327205
Pubmed

Characterization of PKD protein-positive exosome-like vesicles.

PKD2 PKHD1

3.77e-053124219158352
Pubmed

Ethanol inhibition of a T-type Ca²+ channel through activity of protein kinase C.

CACNA1H CACNA1G

3.77e-053124223488970
Pubmed

Differential effect of T-type voltage-gated Ca2+ channel disruption on renal plasma flow and glomerular filtration rate in vivo.

CACNA1H CACNA1G

3.77e-053124224966091
Pubmed

Serum concentrations of CA 125, CA 15-3, CA 19-9 and CEA in normal pregnancy: a longitudinal study.

CEACAM5 MUC16

3.77e-053124221792548
GeneFamilySideroflexins

SFXN1 SFXN3 SFXN2

9.61e-075843746
GeneFamilyDyneins, axonemal

DNAH14 DNAH1 DNAH6

6.28e-0517843536
GeneFamilyCD molecules|V-set domain containing|Immunoglobulin like domain containing|Carcinoembryonic antigen related cell adhesion molecule family

CEACAM5 CEACAM8 CEACAM6

1.82e-0424843906
GeneFamilyGlutamate ionotropic receptor kainate type subunits

GRIK1 GRIK2

2.11e-0458421199
GeneFamilyTransient receptor potential cation channels

PKD2L1 PKD2 TRPM8

2.91e-0428843249
GeneFamilySodium voltage-gated channel alpha subunits

SCN4A SCN5A

7.52e-0498421203
GeneFamilyOxysterol binding proteins|Pleckstrin homology domain containing

OSBPL11 OSBPL10

1.37e-0312842670
GeneFamilySolute carriers

FLVCR1 SLC19A3 SLC6A15 SLC39A10 SLC13A2 SLC17A5 SLC28A2

2.41e-03395847752
GeneFamilyCD molecules|Mucins

MUC3B MUC16

4.23e-0321842648
GeneFamilyCalcium voltage-gated channel subunits

CACNA1H CACNA1G

6.45e-0326842253
ToppCellfacs-Lung-24m-Endothelial-capillary_endothelial-capillary_endothelial_cell-capillary_type_1_endothelial_cell|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ABCA13 NDST4 PKD2L1 ADGRV1 F5 PKHD1 DMBT1

3.26e-071621227bf886e22ff2a20353499004b53f25fb9e6574896
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 POLR2A ADGRV1 DNAH1 PKHD1 TRPM8 DNAH6

4.34e-07169122712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial-EC_cells_(TAC1+)|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A15 GRIK2 SATL1 F5 LGI3 CACNA1H OR56A4

5.49e-071751227182e45f5c02214d6b9f317ff5dc43af8b42de978
ToppCellCOVID-19-Epithelial_cells-Airway_goblet|COVID-19 / group, cell type (main and fine annotations)

CEACAM5 ABCA13 NEXMIF MUC16 CEACAM6 ADGRV1 SCNN1B

9.53e-07190122751ca9ef4df3220487152fcf684147730637c7cc1
ToppCellTracheal-NucSeq|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 EXT1 NF1 SBF2 OSBPL10 COG5 VPS13B

1.30e-06199122794b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC19A3 PKD2L1 DNASE2B PTPRB PKHD1 DMBT1

2.16e-061371226b831d917f5073ccff158662adb281d34f023126a
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-nan|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC19A3 PKD2L1 DNASE2B PTPRB PKHD1 DMBT1

2.16e-061371226cf3e928d9a7a7349840bb87475a42a07f65b94f0
ToppCellfacs-Limb_Muscle-forelimb_and_hindlimb-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

SLC19A3 PKD2L1 DNASE2B PTPRB PKHD1 DMBT1

2.16e-0613712265d82d6c7eef4ec7a7fae60e37fb956488314987e
ToppCellfacs-Lung-Endomucin-24m-Endothelial-Capillary_Type_1_Cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 NDST4 PKD2L1 ADGRV1 PKHD1 DMBT1

3.00e-06145122696712c68ab759d7ade0d912581a1a7c25dc6def8
ToppCellChildren_(3_yrs)-Epithelial-club_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

NEXMIF HS3ST5 GRIK2 ADGRV1 SERPINI1 SCNN1B

1.04e-051801226b509c7d6bdfba672065fb722874bdc68de72ba1c
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 TMPRSS15 ABCA13 ADGRV1 DNAH1 PKHD1

1.18e-0518412262cbed6462fea2622871bb7e49b0df3d984239281
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 TMPRSS15 ABCA13 ADGRV1 DNAH1 PKHD1

1.18e-051841226ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

STK36 TMPRSS15 ABCA13 ADGRV1 DNAH1 PKHD1

1.18e-0518412262b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ADGRV1 DNAH14 CCDC148 PKHD1 OSBPL10

1.33e-051881226af740fa78542438fdff627ea1f74f4eee43316be
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA13 MUC16 ADGRV1 CSMD2 F5 DNAH14

1.63e-051951226d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCellSmart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA13 MUC16 ADGRV1 CSMD2 F5 DNAH14

1.63e-05195122619853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCellParenchymal-NucSeq|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 EXT1 ADGRV1 NF1 COG5 VPS13B

1.78e-0519812261996373bdccc55aac347d349bd22f6aad6d0c668
ToppCellParenchymal-10x5prime-Epithelial-Epi_airway_secretory|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

CEACAM5 ABCA13 MUC16 CEACAM6 SLC13A2 SCNN1B

1.83e-051991226a706ad5cd5e0dc8d7e925a05e45b07d35963f294
ToppCellBronchus_Control_(B.)-Epithelial-TX-Club|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B DMBT1

1.89e-052001226292c63693eb7f435335a8cfba07aa35b72139393
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CEACAM8 CEACAM6 ADGRV1 CSMD2

2.54e-05126122569b2525b92d1c7c35b21cc701f5fa52a9c1b94bb
ToppCellPBMC-Mild-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 CEACAM8 CEACAM6 ADGRV1 CSMD2

2.54e-0512612256cb89754010d64875e115da6c5805efac7a4a82d
ToppCelldroplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_acinar_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PIGB RPP40 COG5

4.83e-05261223e2db677bc0f2011883c8b44058276ecf879d4303
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1-Trf|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PKD2L1 PIWIL4 ADGRV1 DNAH14

5.68e-05761224efbbbf91bca35720d8ecddb076f2c9f4de25e44d
ToppCellEntopeduncular-Macroglia-OLIGODENDROCYTE-O1|Entopeduncular / BrainAtlas - Mouse McCarroll V32

PKD2L1 PIWIL4 ADGRV1 DNAH14

5.68e-05761224254d18bece2676faa4bbeb8d48b1d327ab3c2215
ToppCellEpithelial-Epithelial-B_(AT1-AT2-progenitors)|Epithelial / shred on cell class and cell subclass (v4)

TLK2 LMF2 MRC2 LGI3 CTNNB1

6.61e-051541225770712806e26f73456fb77a81aa4ef8ec78a21ea
ToppCellLPS-antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEACAM5 HS3ST5 SERPINI1 PKHD1 SCNN1B

7.24e-0515712259665a1375cfd8e9b8781c852686591226c0e0d9a
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)-|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDST4 CSMD2 CACNA1G C1QTNF2 GRAMD1C

7.92e-051601225636127753e3a22831f39d4c8170df40901e4329d
ToppCell390C-Fibroblasts-Fibroblast-B_(Myofibroblast)|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)

NDST4 CSMD2 CACNA1G C1QTNF2 GRAMD1C

7.92e-051601225cb8d0dc1a6c69c7a85c5fdd8f0f6cca1b73dfc63
ToppCellLPS-IL1RA-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEACAM5 HS3ST5 SERPINI1 PKHD1 SCNN1B

8.16e-0516112251e17a993126e1f2a25ee7dfbb95a74ccb2a26791
ToppCell10x5'-GI_large-bowel-Lymphocytic_T_CD4-Tregs|GI_large-bowel / Manually curated celltypes from each tissue

F5 SFXN1 THADA PKHD1 DNAH6

8.40e-0516212259a5e65c45f73a6a685b8362aa2e6aea77181caa3
ToppCellPND07-Immune-Immune_Myeloid-Monocytic-Macrophage-IM-IM_G2M|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

SCN4A PKHD1 OSBPL11 CELA1 SYNGR4

9.42e-051661225bb8135119dc37fdbba476599a56d368f422688dc
ToppCellPrimary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PIWIL4 DNAH14 ANTXR2 DNAH6 GRAMD1C

9.96e-051681225bfa1491e8d433933003778b274710d3a16d973cb
ToppCell3'_v3-bone_marrow-Hematopoietic_progenitors-Progenitor_pre-Lymphocytic-T|bone_marrow / Manually curated celltypes from each tissue

ABCA13 CEACAM8 CEACAM6 PIWIL4 VWDE

1.11e-041721225a66402d15853f0c9e3d06394ff9ac08d1da128ff
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Proximal_secretory_2|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MUC16 CEACAM6 SLC13A2 VWDE SCNN1B

1.14e-041731225d1e47c87bd4750801f3531f66a56c5dccb4ea64c
ToppCelldroplet-Limb_Muscle-MUSCLE-1m-Endothelial-unknown|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPP40 F5 LGI3 TMEM268 CACNA1H

1.17e-041741225c58328c2f262506a4518f49f148e29874faf9171
ToppCell5'-Adult-LargeIntestine-Epithelial-neuro-epithelial|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract

SLC6A15 GRIK2 F5 CACNA1H OR56A4

1.17e-0417412259f114e61458659005b6d0b4aa30a7a059e7aa5c6
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)|Adult / Lineage, Cell type, age group and donor

GRIK2 SATL1 F5 VWDE SCN5A

1.21e-0417512254db1a3c284488b3f6de7568363f176d74e2a4587
ToppCellAdult-Epithelial-lung_neuroendocrine_cell_(PNEC)-D231|Adult / Lineage, Cell type, age group and donor

GRIK2 SATL1 F5 VWDE SCN5A

1.21e-0417512258d9f44a2633b71fb4d2b4a7d9530f954e07c4a18
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS3ST5 SLC6A15 ELFN2 DNAH1 CCDC148

1.34e-041791225479116ac65488c60104a053530830763ec1f95b2
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS3ST5 SLC6A15 ELFN2 DNAH1 CCDC148

1.34e-0417912251dfc0cb8b369aef35c59f3d4c52603dc9f3728c1
ToppCellTransplant_Alveoli_and_parenchyma-Epithelial-Type_1_alveolar|Transplant_Alveoli_and_parenchyma / Tissue, Lineage and Cell class of Lung Cells from 10X

CEACAM5 CEACAM6 HS3ST5 GRIK2 SCNN1B

1.34e-041791225d5763912a4ce7188535675e338799b856edb9dda
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-3m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HS3ST5 SLC6A15 ELFN2 DNAH1 CCDC148

1.34e-04179122569a1b3b05c921de6343ffe6ad998aa2b804312a7
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA13 CEACAM8 CEACAM6 PIWIL4 VWDE

1.38e-041801225f598bb9df0d784120847fada2d9a2a88b8b68cd1
ToppCell10x_3'_v3-spleen_(10x_3'_v3)-hematologic-hematopoietic_progenitor-hematopoietic_stem_cell|spleen_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

ABCA13 CEACAM8 CEACAM6 PIWIL4 VWDE

1.38e-041801225b4fa047f271c7b56940bdc85c912f50aa5b5ca82
ToppCellCOVID-19-Epithelial-Ionocytes|Epithelial / Condition, Lineage and Cell class

PKD2L1 GRIK1 VWDE SCNN1B CACNA1H

1.41e-0418112254a8d4f2709c1b25f908867f1b2fae1d2d0abf1d4
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-nan|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD2L1 SLC13A2 SCNN1B OSBPL10 DMBT1

1.41e-0418112253fd16229a63de0971db5d48860c01173d7db518f
ToppCellrenal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 ADGRV1 CCDC148 PKHD1 OSBPL10

1.41e-0418112259d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCellLPS-IL1RA+antiTNF-Epithelial_alveolar-AT_1-AT1|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

CEACAM5 HS3ST5 SERPINI1 PKHD1 SCNN1B

1.49e-041831225274483009b309289e4cb84beedf6806430db6ff6
ToppCelldroplet-Heart-4Chambers-21m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD2L1 SLC13A2 SCNN1B OSBPL10 DMBT1

1.49e-0418312254de2082dca2569d3aac3c9b466f27971c82d302b
ToppCellCOVID-19-lung-AT1|lung / Disease (COVID-19 only), tissue and cell type

CEACAM6 HS3ST5 ADGRV1 DNAH14 SCNN1B

1.49e-041831225942530449e9c6583705eeb8f6f12621daea57252
ToppCelldroplet-Heart-4Chambers-21m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PKD2L1 SLC13A2 SCNN1B OSBPL10 DMBT1

1.49e-041831225a046b569bc10083d471b420eb2c6fee93437602d
ToppCellCOVID-19-kidney-PCT-S1|kidney / Disease (COVID-19 only), tissue and cell type

BIN1 ABCA13 AGMO PKHD1 OSBPL10

1.53e-04184122551ed1ebfdef45149541917c66cbacad87072e51f
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)-Goblet_(bronchial)_L.0.4.2.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 MUC16 CEACAM6 ADGRV1 SCNN1B

1.53e-04184122501c19a830348ab0b9c02c1546a439de70ee10f97
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

NEXMIF CEACAM6 HS3ST5 ADGRV1 SCNN1B

1.56e-041851225cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 DNAH14 CCDC148 PKHD1 OSBPL10

1.60e-041861225f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCellAdult-Epithelial-club_cell-D231|Adult / Lineage, Cell type, age group and donor

HS3ST5 GRIK2 ADGRV1 SERPINI1 SCNN1B

1.64e-041871225ee59d7d3de5879738ff0b9c3ea5e4847fb48cb86
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Degenerative_Descending_Thin_Limb_Cell_Type_3|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 DNAH14 CCDC148 PKHD1 OSBPL10

1.64e-041871225c31130fc2f9f882944b2ba366a034a03f051c4b9
ToppCell356C-Lymphocytic-CD4_T-cell-Treg_cell_3|CD4_T-cell / Donor, Lineage, Cell class and subclass (all cells)

NRDC FLVCR1 SRP72 F5 EEF1AKMT1

1.73e-04189122599b01893da9f9f7c9528afaffad178285211738b
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Macula_Densa_Cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

NEXMIF ADGRV1 CCDC148 DNAH6 GRAMD1C

1.73e-041891225e059be2965cca70ff5576df055d0af1775b76e00
ToppCellAdult-Epithelial-club_cell|Adult / Lineage, Cell type, age group and donor

HS3ST5 GRIK2 ADGRV1 SERPINI1 SCNN1B

1.77e-041901225756bff697d30aec56c0ebfca94295f084a15bf37
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HS3ST5 GRIK1 GRIK2 EXT1 ADAMTSL3

1.77e-04190122556cc761e50fddfb5366391518b4d8e16589b6b42
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell-Goblet_(bronchial)|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

1.77e-04190122523f2ac4da431211084bb6ab0494c2e0b69547cb6
ToppCellSomatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HS3ST5 GRIK1 GRIK2 EXT1 ADAMTSL3

1.77e-04190122525d4b591f75c26e404a34c42f1742d580af6598d
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-bronchial_goblet_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

1.77e-0419012253c337374d89e69cc0a78e65a4a7e21db7b050fcd
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.81e-0419112256c1283d51a845cff67ed5e500f7e944165297b53
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ABCA13 DNAH14 PKHD1 OSBPL10

1.81e-041911225d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 DNAH14 UBE2H PKHD1 OSBPL10

1.81e-0419112259032aa974aa1b7b1095b8d1b58dcb087358a5001
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 DNAH14 UBE2H PKHD1 OSBPL10

1.81e-0419112255717809a1476c20f65bce722c5a57cff92ee0d7a
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.86e-04192122586d561c30554ff04c21801d4aaf8e3c9efe49af4
ToppCellCOVID-19_Severe-Myeloid_G-immature_Neutrophil|COVID-19_Severe / Disease group, lineage and cell class

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.86e-041921225303deb68da2e4a75e6ee5a79478182a8bc41c7c5
ToppCellcontrol-Myeloid-Immature_Neutrophils_1|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CATSPERE ABCA13 CEACAM8 CEACAM6 SFXN1

1.86e-0419212259f12b79d661ef0f57c2c924e8ecc24a46ea996d2
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

SLC19A3 ADGRV1 DNAH14 PKHD1 DMBT1

1.86e-041921225fb2f0e897228f808d9ff734ad05e9b49dc38fa50
ToppCellmild-Myeloid-Immature_Neutrophils_2|mild / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.86e-0419212250445fdc670fa7b847dcd0a061d7736ddcf3519ba
ToppCellrenal_cortex_nuclei|World / Celltypes from Cells and Nuclei per compartment and clinical group

EXT1 SBF2 PKHD1 OSBPL10 VPS13B

1.86e-041921225e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

1.90e-04193122571bf8fb5314b79cb30f4eb9c8459b21f10cd6d35
ToppCellEpithelial-club_cell|World / Lineage, Cell type, age group and donor

NEXMIF HS3ST5 GRIK2 ADGRV1 SCNN1B

1.90e-0419312252bdd09004fa433550958ec42ba4b06271a4aaf7c
ToppCellcellseq-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

1.90e-041931225b05e110b13d35d34294357c8e1c4fd23bf4b6c92
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.90e-041931225ccab6a0c76f574ef7e1d6d5f1e620376daf21bbf
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|control / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.90e-04193122533349830e9eba506470ad3661fad5e5a283d20ca
ToppCellPCW_13-14-Epithelial-Epithelial_neuroendo|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

PKD2L1 GRIK2 ADGRV1 VWDE CACNA1H

1.90e-0419312258603d1a38955ad2529d04e4704467c73ea5bfbda
ToppCellcellseq-Epithelial-Epithelial_Glandular|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CEACAM5 MUC16 CEACAM6 SLC13A2 DMBT1

1.95e-041941225d0fb1ff5cf0738881e114a58f0b27489f781d72b
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)|390C / Donor, Lineage, Cell class and subclass (all cells)

PIEZO1 CEACAM6 HS3ST5 SCNN1B PPIP5K2

1.95e-04194122588db9f9e80c20ff3474f1f6459dcbdc25aec0b6d
ToppCellPBMC-Severe-Myeloid-Neutrophil-immature_Neutrophil-Neu_4|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

1.95e-04194122523318a1b55895b5166c6151f488a94a09b4627ff
ToppCell390C-Epithelial_cells-Epithelial-I_(AT1)-|390C / Donor, Lineage, Cell class and subclass (all cells)

PIEZO1 CEACAM6 HS3ST5 SCNN1B PPIP5K2

1.95e-041941225a71728202493d4858342ea2756ea281cd0d99a3a
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ELFN2 UBE2H PKHD1 OSBPL10

2.00e-041951225938b31dbf1674ee6fd0123bc88391ddcaf151217
ToppCell3'-Distal_airway-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-Goblet_(subsegmental)_L.0.4.3.0|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

ABCA13 MUC16 CEACAM6 TMBIM6 SCNN1B

2.00e-0419512252a9a36df1dbc4eac77a8ddbe939ec8a8d6c41464
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

DOCK1 ELFN2 UBE2H PKHD1 OSBPL10

2.00e-041951225d39e9e6544f49e677ebe528c6fe60b99a3630e30
ToppCellcontrol-Myeloid-Immature_Neutrophils_2|Myeloid / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

ABCA13 CEACAM8 CEACAM6 HS3ST5 PIWIL4

2.00e-041951225bfaceb0601cf3855f38d6e1f482f01ad03ef11fe
ToppCellBronchial-NucSeq|Bronchial / Cell types per location group and 10X technology with lineage, and cell group designations

DOCK1 EXT1 ADGRV1 COG5 VPS13B

2.05e-041961225ab53c742866945545a92e2e61850d63c80d9a2a6
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

2.05e-041961225c18874f37b90e6afacc562b2082b67ea8a7cb4a4
ToppCellCOVID-19-kidney-TAL|kidney / Disease (COVID-19 only), tissue and cell type

NEXMIF ADGRV1 CCDC148 PKHD1 CACNA1H

2.05e-04196122504f5eb206ed3016a737609a3ebac0c1fcabb94ef
ToppCellwk_20-22-Epithelial-Proximal_epithelial-Club|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CEACAM5 CEACAM6 GRIK2 ADGRV1 SCNN1B

2.05e-0419612254e4c632db73b1340d80bf40a7657cb4821084d3c
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CEACAM5 MUC16 CEACAM6 SLC13A2 SCNN1B

2.05e-041961225a4d05d85fbafa869df19bba3881020ea433d81fb
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

CEACAM5 MUC16 CEACAM6 SLC13A2 SCNN1B

2.05e-04196122591a3c3091064f1f5a3bdc1dd5883fc24dce8ff05
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

CEACAM5 MUC16 CEACAM6 SLC13A2 SCNN1B

2.05e-041961225e819088a74d29e958371aa851ac9c74ec55367b7
ToppCellBAL-Mild-Epithelial-Epithelial-Basal/Club|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

CEACAM5 MUC16 CEACAM6 SLC13A2 SCNN1B

2.05e-041961225e675d661b6494ac3a85ba7ee5bdeaa98b8bbe957
ToppCellBronchial_Biopsy-Epithelial-Club|Bronchial_Biopsy / Tissue, Lineage and Cell class of Lung Cells from 10X

CEACAM5 MUC16 CEACAM6 SLC13A2 SCNN1B

2.05e-041961225057d150bdf0cad959fd03ec2d1560a96ba03fae9
ToppCelldistal-Epithelial-Goblet|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

2.09e-041971225da1ed7303cc9cb2d205c0e5c49c52544d3540951
ToppCelldistal-3-Epithelial-Goblet|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CEACAM5 ABCA13 MUC16 CEACAM6 SCNN1B

2.09e-041971225a00784ccfb1de6a96b91e2a8a2889b69f31a33da
ToppCellBronchial_Biopsy-Epithelial-Club|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X

CEACAM5 MUC16 CEACAM6 SLC13A2 SCNN1B

2.09e-0419712253f5dfa892a1f631b96eeb6f4cfc284aee51d1ce6
DrugZonisamide

SCN4A SCN5A CACNA1H CACNA1G

1.66e-06171204DB00909
Druglamotrigine

GRIK1 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

2.75e-061161207CID000003878
Drugriluzole

GRIK1 GRIK2 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

4.02e-061741208CID000005070
DrugNSC7524

GRIK1 ADORA2A SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

5.60e-061821208CID000005657
DrugIsocarboxazid [59-63-2]; Down 200; 17.2uM; MCF7; HT_HG-U133A

DOCK1 BIN1 LMF2 NF1 LPCAT3 CACNA1H ALDH1B1 GRAMD1C

9.29e-0619512084706_DN
Drugmethanethiosulfonate

STK36 GRIK1 SLC13A2 SCN4A SCN5A SCNN1B

1.78e-051031206CID004188587
Drugoxcarbazepine

SCN4A SCN5A SCNN1B CACNA1H

1.81e-05301204CID000034312
Drugphenytoin

STK36 LGI3 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

2.15e-052191208CID000001775
DrugFlecainide

SCN4A SCN5A

2.75e-0521202DB01195
Drug5-nitro-6,7,8,9-tetrahydrobenzo(G)indole-2,3-dione-3-oxime

GRIK1 GRIK2

2.75e-0521202ctd:C084273
Drugthemisone

CACNA1H CACNA1G TBCE

3.03e-05121203CID000016235
Drugchlordiazepoxide

DOCK1 FNTA OCRL CACNA1H PARN CACNA1G

3.17e-051141206CID000002712
Druggabapentin

GRIK1 SCN4A SCN5A PKD2 SCNN1B CACNA1H CACNA1G

3.23e-051691207CID000003446
Drugtetralol

SCN5A CACNA1H CACNA1G

3.93e-05131203CID000010747
Diseasecardiac troponin T measurement

TLK2 GRIK1 NF1 MRC2 PKHD1 PPIP5K2 IPMK

2.80e-052191177EFO_0005043
Diseasepolycystic kidney disease 2 (implicated_via_orthology)

PKD2L1 PKD2

4.66e-0531172DOID:0110859 (implicated_via_orthology)
DiseaseC-type mannose receptor 2 measurement

TLK2 MRC2

9.30e-0541172EFO_0020204
Diseaselevel of Sterol ester (27:1/18:2) in blood serum

TDRD15 HNF1A NKPD1

1.48e-04261173OBA_2045194
Diseasehematocrit

TDRD15 STK36 HNF1A PIEZO1 FLVCR1 ADGRV1 SLC39A10 VAC14 SBF2 AGMO PKHD1 DMBT1 SPRTN

1.91e-04101111713EFO_0004348
Diseasecortisol secretion measurement

SLC19A3 EXT1

3.23e-0471172EFO_0004642
DiseaseMalignant neoplasm of breast

CATSPERE GRIK2 PKDREJ ZDHHC4 LMF2 NF1 JMJD6 SCNN1B OSBPL11 CELA1 CTNNB1 EIF3M VPS13B

3.43e-04107411713C0006142
DiseaseColonic Neoplasms

GRIK2 F5 DMBT1 CTNNB1 ALDH1B1

3.58e-041521175C0009375
Diseasechildhood absence epilepsy (is_implicated_in)

GRIK1 CACNA1H

4.30e-0481172DOID:1825 (is_implicated_in)
Diseasehypokalemic periodic paralysis (implicated_via_orthology)

SCN4A SCNN1B

4.30e-0481172DOID:14452 (implicated_via_orthology)
DiseaseMalignant tumor of colon

GRIK2 F5 DMBT1 CTNNB1 ALDH1B1

4.40e-041591175C0007102
DiseaseHepatocellular Adenoma

HNF1A CTNNB1

5.51e-0491172C0206669
Diseaselevel of Sterol ester (27:1/16:1) in blood serum

HNF1A PKD2L1

5.51e-0491172OBA_2045190
DiseaseCutaneous Melanoma

NF1 JMJD6 CTNNB1

5.80e-04411173C0151779
Diseasegeneralized epilepsy with febrile seizures plus 2 (implicated_via_orthology)

SCN4A SCN5A

6.87e-04101172DOID:0111294 (implicated_via_orthology)
DiseaseDravet syndrome (implicated_via_orthology)

SCN4A SCN5A

6.87e-04101172DOID:0080422 (implicated_via_orthology)
Diseasered blood cell density measurement

STK36 HNF1A PIEZO1 FLVCR1 ADGRV1 VAC14 UBE2H SBF2 PKHD1 VPS13B PGBD2

7.67e-0488011711EFO_0007978
Diseasephosphatidylcholine measurement

TDRD15 HNF1A PKD2L1 GRIK2 LPCAT3 PARN

9.66e-042841176EFO_0010226
DiseaseCiliopathies

ADGRV1 PKD2 PKHD1 SCNN1B

9.81e-041101174C4277690
Diseasegeneralized epilepsy with febrile seizures plus (implicated_via_orthology)

SCN4A SCN5A

1.00e-03121172DOID:0060170 (implicated_via_orthology)
DiseaseVaricose veins

PIEZO1 ADGRV1 ATP13A2 UBE2H SBF2

1.05e-031931175HP_0002619
Diseaseendometrial carcinoma

SLC6A15 EXT1 CSMD2 NF1

1.08e-031131174EFO_1001512
DiseaseNeurodegeneration with brain iron accumulation

ATP13A2 TBCE

1.18e-03131172cv:C2931845
Diseaseabdominal adipose tissue measurement

ADAMTSL3 SCN4A PKHD1

1.23e-03531173EFO_0803316
Diseaseautosomal dominant polycystic kidney disease (implicated_via_orthology)

PKD2L1 PKD2

1.38e-03141172DOID:898 (implicated_via_orthology)
DiseaseGeneralized hypotonia

PIGB POLR2A

1.58e-03151172C1858120
DiseasePheochromocytoma, Extra-Adrenal

TMEM127 NF1

1.80e-03161172C1257877
Diseaseovarian neoplasm

MUC16 GRIK2 JMJD6 CTNNB1

2.03e-031341174C0919267
DiseaseMalignant neoplasm of ovary

MUC16 GRIK2 JMJD6 CTNNB1

2.20e-031371174C1140680
DiseaseHemangiosarcoma

PTPRB CTNNB1

2.29e-03181172C0018923
Diseaselevel of Sterol ester (27:1/20:3) in blood serum

HNF1A PARN

2.55e-03191172OBA_2045199
DiseasePheochromocytoma

TMEM127 NF1

2.55e-03191172C0031511
Diseaseneurodegenerative disease (implicated_via_orthology)

NRDC GRIK1 GRIK2 SCNN1B

2.70e-031451174DOID:1289 (implicated_via_orthology)
Diseaseserum carcinoembryonic antigen measurement

CEACAM5 CEACAM6

2.83e-03201172EFO_0005760
Diseasemelanoma

HS3ST5 SLC17A5 NF1 JMJD6 CTNNB1

3.15e-032481175C0025202
Diseaseautism spectrum disorder (implicated_via_orthology)

NEXMIF NDST4 EXT1 CTNNB1

3.20e-031521174DOID:0060041 (implicated_via_orthology)
Diseasecortical thickness change measurement, age at assessment

SLC6A15 GRIK2

3.73e-03231172EFO_0008007, EFO_0021501
DiseaseHereditary Paraganglioma-Pheochromocytoma Syndrome

TMEM127 NF1

3.73e-03231172C1708353
DiseaseAutistic Disorder

GRIK2 EXT1 NF1 UBE2H CACNA1H

3.91e-032611175C0004352

Protein segments in the cluster

PeptideGeneStartEntry
SLTRQEFWQLLQQNY

GRAMD1C

181

Q8IYS0
SVNFVNYWQKNSTRL

ERVK-18

386

O42043
YRFAIEQQNILISNW

CCDC148

311

Q8NFR7
FFNNFTQLITVWAYD

CATSPERE

111

Q5SY80
WRLIFETQYQFQAQL

CSMD2

2606

Q7Z408
VWLNSNLQNVTNYFV

ADORA2A

31

P29274
QFNLLYQFWIHTEVI

AGMO

191

Q6ZNB7
YNQLFINNEWQDAVS

ALDH1B1

36

P30837
WFVNGTFQQSTQELF

CEACAM5

271

P06731
WSVNGTFQQYTQKLF

CEACAM8

271

P31997
VVENNFTLLNSFWFG

GRIK1

616

P39086
YFGSVSVSWQLFQND

ADGRV1

1146

Q8WXG9
QFTEYSSQQWFISGN

ADGRV1

5796

Q8WXG9
ANNWIEIYNFVQQLA

ANTXR2

56

P58335
VYQQVFVQWQQGSLL

ABCA13

351

Q86UQ4
LYQLFSAFGNIQISW

PARN

461

O95453
FFAQIHPNYLTQQWQ

PAQR3

186

Q6TCH7
TFNQLYQFVAGWTLL

OR56A4

196

Q8NGH8
EEFNTWVNNTYVFFV

RSPH10B2

756

B2RC85
WVNNTYVFFVNTLFH

RSPH10B2

761

B2RC85
EYQINFHIVNWNLSN

MUC16

14201

Q8WXI7
AVSQWLTAFQLQLYA

CASKIN1

476

Q8WXD9
QVLYEWEQGFSQSFT

CTNNB1

61

P35222
LFTNWTQAQGDVEFY

PTPRB

571

P23467
GNQQDEAITWFNVIY

JMJD6

226

Q6NYC1
RVFTNNQVSYTSWFL

MBTPS1

276

Q14703
QQFWETTFYNAVQEQ

SBF2

666

Q86WG5
WFINGTFQQSTQELF

CEACAM6

271

P40199
TFGKQQWQQLYDTLN

EIF3M

341

Q7L2H7
NWNYGQVTLNETVKF

TMPRSS15

461

P98073
EVWLQIFYSEQNGLF

C1QTNF2

246

Q9BXJ5
FNQKFYQITGRTLNW

HS3ST5

331

Q8IZT8
QWTFGKNNRLYQVSV

GALNT11

561

Q8NCW6
SQFWYSQETALQLAQ

EEF1AKMT1

51

Q8WVE0
SFNINTNAWVARYIF

LPCAT3

336

Q6P1A2
NRFEQAFVSSLIYNW

MRC2

561

Q9UBG0
SNLVTEVRVYNWFAN

HNF1A

256

P20823
FTQVSAYISWINNVI

CELA1

241

Q9UNI1
QWLIDTLYAFNSGNV

PSMD13

231

Q9UNM6
YTFVNLVNFVQSWTN

NDST4

531

Q9H3R1
ILQWFENQKQLNFYA

IPMK

236

Q8NFU5
SYFWQGQILSATQEQ

ITGA5

226

P08648
QPEIFYTFWNSVTQA

COG5

376

Q9UP83
VVSVNDFQWISQLRY

DNAH1

1511

Q9P2D7
YLFQGQRYIWIETQQ

ATP13A2

166

Q9NQ11
QRYIWIETQQAFYQV

ATP13A2

171

Q9NQ11
VYNSFLNNQVPALWS

DNAH6

3936

Q9C0G6
TQNWQIYQAFQGLVL

DNASE2B

341

Q8WZ79
FLDQANFELQLWNNY

DOCK1

1011

Q14185
QQTQFLWEAYFSSVE

EXT1

406

Q16394
NFDNIGYAWIAIFQV

CACNA1G

336

O43497
NVFFGSIWLFQANLY

TMBIM6

161

P55061
NAFQWIQYSIISNVF

FLVCR1

121

Q9Y5Y0
QYNQSQKDILQSWFQ

DUXB

21

A0A1W2PPF3
NFFNTWAKVAYTAIQ

DNAH14

3271

Q0VDD8
SQIQQYQFWQFHKGN

MS4A14

646

Q96JA4
RASQGISNYLAWFQQ

IGKV1-16

46

P04430
VVENNFTLLNSFWFG

GRIK2

601

Q13002
WNSRVGFYVNTFQSI

BIN1

231

O00499
FDNIGYAWIAIFQVI

CACNA1H

361

O95180
SDISFQNTGFLAWYN

DMBT1

1861

Q9UGM3
QNGNVVNFASWFSFA

SLC13A2

256

Q13183
WQTVFYIAAAINVFG

SLC17A5

456

Q9NRA2
GFNQVLNYVQILWDY

SLC19A3

291

Q9BZV2
TEWYILQATNIFAQV

SCNN1B

216

P51168
AVGQYANNITLWIFA

SLC39A10

751

Q9ULF5
YATQWLLYAQNLVQI

RXYLT1

176

Q9Y2B1
LVTGWQYRFFVLNNE

OSBPL11

71

Q9BXB4
FSQNVAVANYINKWV

SERPINI1

141

Q99574
TSQAYRDFNKTFWNQ

MUC3B

956

Q9H195
FVIFNNQDYWLQMAV

RPP40

341

O75818
VQFNFLKFNVLQNWG

PIGB

286

Q92521
NFANGFIALINFIAW

TAS2R20

21

P59543
SNNQYARQFIISWIL

VAC14

186

Q08AM6
IIGWSLFYFSQSFQQ

SLC6A15

161

Q9H2J7
QWIQFFITYNLNSQS

THADA

661

Q6YHU6
WVNQSFNAIVNYSNR

SFXN3

121

Q9BWM7
WVNQSFNALVNYTNR

SFXN2

121

Q96NB2
EYFQQGWNIFDSIIV

SCN4A

636

P35499
QWINQSFNAVVNYTN

SFXN1

121

Q9H9B4
IKSFTWVQFQNDRQY

TDRD15

1721

B5MCY1
WVQFQNDRQYSGIAT

TDRD15

1726

B5MCY1
AYSSNQINWQIFKGN

F5

1996

P12259
QVGQVFLYFQWDSLL

LMF2

116

Q9BU23
NVQFLFIRFSAWQYA

NKPD1

51

Q17RQ9
LANSNQDWGYFETFI

NEXMIF

251

Q5QGS0
NSLQWGVYVFNFTVS

PKDREJ

296

Q9NTG1
VRNNSVWNQRYFVIS

FNTA

231

P49354
NLFNLDFPQDWQLYQ

PIWIL4

111

Q7Z3Z4
FLVVIWNQASINYYT

SATL1

651

Q86VE3
YFQQGWNIFDSIIVI

SCN5A

776

Q14524
NNYTFWIQADSQASL

PKHD1

386

P08F94
IEVFTQAIQWYQNHQ

SRP72

426

O76094
NIQTFRFFVGTWNVN

OCRL

236

Q01968
NLLQGWQNRYFVLDF

OSBPL10

86

Q9BXB5
FQWLGEQVQIFLNYT

SLC28A2

226

O43868
NSLQQQSWYGTFLQD

STK36

516

Q9NRP7
QWTDGYAFQNLIKQQ

TLK2

311

Q86UE8
YIQNFKWTDTLQGQV

BROX

86

Q5VW32
FIVNETNRYAWQKNV

PGBD2

156

Q6P3X8
QNYGELFSNQIIWFV

PRPF8

1766

Q6P2Q9
QSVIQLWFVYFDLEN

TMEM268

191

Q5VZI3
QNFNNYVAFINEWRI

VWDE

586

Q8N2E2
IYQWVSRSGQNNSVF

VPS25

111

Q9BRG1
INQTWTALYDLTNIF

UBE2H

91

P62256
YLVVNDNQISQWSFF

TBCE

311

Q15813
HINNLYNTVFWALIQ

THG1L

181

Q9NWX6
YNTVFWALIQQSGLT

THG1L

186

Q9NWX6
RLFYSNIQTVINNWL

POLR2A

666

P24928
FVLYLAATNQTTNEW

ZDHHC4

276

Q9NPG8
LDQWTELAQRFAFQY

NF1

2226

P21359
VDRNWNEVVTQQYLF

NRDC

1036

O43847
SVNFQTTWSQAQQYL

PRPF40B

426

Q6NWY9
NDVLIWFGYLNSTFN

TAAR1

286

Q96RJ0
VWIFQAYLAFQDLRN

SYNGR4

156

O95473
PNFEHLAYWQIQFNN

PKD2

546

Q13563
LAYWQIQFNNIAAVT

PKD2

551

Q13563
IQFNNIAAVTVFFVW

PKD2

556

Q13563
ADFEFLAFWQTQYNN

PKD2L1

426

Q9P0L9
QALFVQFNDQFFWGQ

SPRTN

46

Q9H040
VTFEDVAVYFTQNQW

ZNF621

11

Q6ZSS3
NFQEAFQIGIYWANT

VPS13B

3021

Q7Z7G8
QQIVIFTFWTFANYL

TAS2R8

81

Q9NYW2
QSAFQLAYQAWVTNA

PIEZO1

1441

Q92508
IFGSWQQVVSENANY

PPIP5K2

1026

O43314
VQENNDQVWKFQRYF

TRPM8

986

Q7Z2W7
VYWYQQSLDQGLQFL

TRBV9

51

A0A0B4J1U6
FSYWASELILAQQQQ

TMEM127

146

O75204
FLAWLVVFNNVTKNY

ELFN2

196

Q5R3F8
VQFFFYQPISHQWRQ

ADAMTSL3

331

P82987
IYQWSRTQKQFVAQG

LGI3

401

Q8N145