Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionendopeptidase activity

ADAM19 RHBDF1 KLK3 ADAM12 NLN CPNE1 MMP26 ESPL1 MMP16 CTSK KLK2

4.55e-0543011711GO:0004175
DomainIQ

MYO5B MYO9B OBSCN ASPM UBE3C IQCE

4.46e-06711136PF00612
DomainIQ

MYO5B MYO9B OBSCN ASPM UBE3C IQCE

9.63e-06811136SM00015
DomainIQ_motif_EF-hand-BS

MYO5B MYO9B OBSCN ASPM UBE3C IQCE

1.77e-05901136IPR000048
DomainIQ

MYO5B MYO9B OBSCN ASPM UBE3C IQCE

2.13e-05931136PS50096
DomainTeashirt_fam

TSHZ3 TSHZ2

1.08e-0431132IPR027008
Domain-

ADAM19 ADAM12 NLN MMP26 MMP16

1.32e-048111353.40.390.10
DomainMetalloPept_cat_dom

ADAM19 ADAM12 NLN MMP26 MMP16

1.32e-04811135IPR024079
DomainKinesin-like_KIF1-typ

KIF13B KIF1B

2.16e-0441132IPR022140
DomainKIF1B

KIF13B KIF1B

2.16e-0441132PF12423
DomainZINC_PROTEASE

ADAM19 ADAM12 NLN MMP26 MMP16

3.22e-04981135PS00142
DomainKinesin_assoc

KIF13B KIF1B

5.36e-0461132PF16183
DomainKinesin-like

KIF13B KIF1B

5.36e-0461132IPR022164
DomainKinesin_assoc

KIF13B KIF1B

5.36e-0461132IPR032405
DomainDUF3694

KIF13B KIF1B

5.36e-0461132PF12473
DomainPlexin_cytopl

PLXND1 PLXNA1

1.27e-0391132PF08337
DomainPlexin_cytoplasmic_RasGAP_dom

PLXND1 PLXNA1

1.27e-0391132IPR013548
DomainPlexin

PLXND1 PLXNA1

1.27e-0391132IPR031148
DomainCYSTEINE_SWITCH

ADAM19 MMP26 MMP16

1.94e-03411133PS00546
DomainRho_GTPase_activation_prot

MYO9B PLXND1 ARHGAP35 PLXNA1

2.00e-03881134IPR008936
DomainPept_M10_metallopeptidase

ADAM19 MMP26 MMP16

2.23e-03431133IPR001818
DomainDisintegrin_CS

ADAM19 ADAM12

4.12e-03161132IPR018358
DomainADAM_CR

ADAM19 ADAM12

5.21e-03181132PF08516
DomainP-loop_NTPase

KIF13B RAB25 MYO5B MYO9B KIF1B CHD2 ARHGAP35 MMAA ABCA5 ASPM ABCC2 DSEL

5.24e-0384811312IPR027417
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

KIF13B PNN MYO5B MRPL47 NSD2 UGGT1 UBR4 ANKRD30B CHD2 TEX10 TLK1 H4C7 CYB5R3 ASPM MACF1 AATF ATM DMD ABCC2

5.24e-0714421201935575683
Pubmed

Human Tousled like kinases are targeted by an ATM- and Chk1-dependent DNA damage checkpoint.

TLK2 TLK1 ATM

7.95e-076120312660173
Pubmed

Construction of long-transcript enriched cDNA libraries from submicrogram amounts of total RNAs by a universal PCR amplification method.

TLK2 KIF13B MBTD1 RAPGEF6 RHBDF1 CEP162 UGGT1 OBSCN CHD2 WDHD1 PAPOLA NFRKB MACF1 AATF DOT1L ESPL1

1.06e-0610841201611544199
Pubmed

Tagging genes with cassette-exchange sites.

MBTD1 UGGT1 UBR4 DMXL1 TLK1 CYB5R3 MACF1 AATF PLXNA1

2.63e-06335120915741177
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

RAPGEF6 RHBDF1 MYO9B NSD2 UBR4 OBSCN PLXND1 ARHGAP35 TLK1 A4GALT UBE3C DOT1L ESPL1 PLXNA1 IQCE

6.50e-0611051201535748872
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

KIF13B TBC1D30 MYO5B ARHGAP35 JMJD1C TLK1 FIG4 LRRCC1 MACF1 PDZRN3

8.64e-064931201015368895
Pubmed

Identification of phagocytosis regulators using magnetic genome-wide CRISPR screens.

MYO9B UGGT1 UBR4 ARHGAP35 CPNE1 MACF1

1.08e-05143120630397336
Pubmed

Genetic variation in KLK2 and KLK3 is associated with concentrations of hK2 and PSA in serum and seminal plasma in young men.

KLK3 KLK2

1.18e-052120224270797
Pubmed

The predictive value of prostate cancer biomarkers depends on age and time to diagnosis: towards a biologically-based screening strategy.

KLK3 KLK2

1.18e-052120217657743
Pubmed

The expression of Tousled kinases in CaP cell lines and its relation to radiation response and DSB repair.

TLK2 TLK1

1.18e-052120221647934
Pubmed

Evaluation of molecular forms of prostate-specific antigen and human kallikrein 2 in predicting biochemical failure after radical prostatectomy.

KLK3 KLK2

1.18e-052120219003994
Pubmed

Detection of FLT3/TKD and IDH1 Mutations in Pakistani Acute Myeloid Leukemia Patients by Denaturing HPLC.

FLT3 IDH1

1.18e-052120227735988
Pubmed

Proteomic analysis of patient tissue reveals PSA protein in the stroma of benign prostatic hyperplasia.

KLK3 KLK2

1.18e-052120224711254
Pubmed

Tousled-Like Kinases Suppress Innate Immune Signaling Triggered by Alternative Lengthening of Telomeres.

TLK2 TLK1

1.18e-052120232755577
Pubmed

cDNA cloning and chromosomal mapping of genes encoding novel protein kinases termed PKU-alpha and PKU-beta, which have nuclear localization signal.

TLK2 TLK1

1.18e-05212029427565
Pubmed

Transgenic overexpression of ADAM12 suppresses muscle regeneration and aggravates dystrophy in aged mdx mice.

ADAM12 DMD

1.18e-052120217982130
Pubmed

Conditional abrogation of Atm in osteoclasts extends osteoclast lifespan and results in reduced bone mass.

ATM CTSK

1.18e-052120227677594
Pubmed

Influence of IDH on FLT3-ITD status in newly diagnosed AML.

FLT3 IDH1

1.18e-052120228751773
Pubmed

Risk assessment for biochemical recurrence prior to radical prostatectomy: significant enhancement contributed by human glandular kallikrein 2 (hK2) and free prostate specific antigen (PSA) in men with moderate PSA-elevation in serum.

KLK3 KLK2

1.18e-052120216152616
Pubmed

Ethnic variation in kallikrein expression in nipple aspirate fluid.

KLK3 KLK2

1.18e-052120212209605
Pubmed

Unusual alternative splicing within the human kallikrein genes KLK2 and KLK3 gives rise to novel prostate-specific proteins.

KLK3 KLK2

1.18e-052120211834722
Pubmed

Detection of prostate specific transcripts in the peripheral blood during brachytherapy predicts postoperative PSA kinetics.

KLK3 KLK2

1.18e-052120219434652
Pubmed

Rare and frequent promoter methylation, respectively, of TSHZ2 and 3 genes that are both downregulated in expression in breast and prostate cancers.

TSHZ3 TSHZ2

1.18e-052120221423795
Pubmed

Early prediction of prostate cancer biochemical recurrence and identification of disease persistence using PSA isoforms and human kallikrein-2.

KLK3 KLK2

1.18e-052120234486998
Pubmed

Tagging SNPs in the kallikrein genes 3 and 2 on 19q13 and their associations with prostate cancer in men of European origin.

KLK3 KLK2

1.18e-052120217593395
Pubmed

Compensation for dystrophin-deficiency: ADAM12 overexpression in skeletal muscle results in increased alpha 7 integrin, utrophin and associated glycoproteins.

ADAM12 DMD

1.18e-052120212915458
Pubmed

Microtubule-Actin Crosslinking Factor 1 Is Required for Dendritic Arborization and Axon Outgrowth in the Developing Brain.

MACF1 NEUROD6

1.18e-052120226526844
Pubmed

Molecular alterations of the IDH1 gene in AML: a Children's Oncology Group and Southwest Oncology Group study.

FLT3 IDH1

1.18e-052120220376086
Pubmed

Predictive value of four kallikrein markers for pathologically insignificant compared with aggressive prostate cancer in radical prostatectomy specimens: results from the European Randomized Study of Screening for Prostate Cancer section Rotterdam.

KLK3 KLK2

1.18e-052120223683475
Pubmed

Large-scale characterization of HeLa cell nuclear phosphoproteins.

TLK2 RAPGEF6 PNN KIF1B ARHGAP35 LIG1 TLK1 WDHD1 PAPOLA NFRKB ATM ESPL1

1.59e-057741201215302935
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

PNN NSD2 UGGT1 UBR4 CHD2 TEX10 CRNKL1 OASL MACF1 AATF ATM

1.72e-056531201122586326
Pubmed

Plexin-A3 mediates semaphorin signaling and regulates the development of hippocampal axonal projections.

PLXND1 NEUROD6 PLXNA1

2.63e-0517120311683995
Pubmed

Critical role of tissue kallikrein in vessel formation and maturation: implications for therapeutic revascularization.

KLK3 KLK2

3.53e-053120219164804
Pubmed

Regional and global protective effects of tissue kallikrein gene delivery to the peri-infarct myocardium.

KLK3 KLK2

3.53e-053120217465807
Pubmed

Mouse kallikrein arginyl-esteropeptidase genes: analysis of cloned cDNAs suggests rapid functional divergence from a common ancestral sequence.

KLK3 KLK2

3.53e-05312026926406
Pubmed

7S Nerve growth factor alpha and gamma subunits are closely related proteins.

KLK3 KLK2

3.53e-05312026712944
Pubmed

Discovery of Stromal Regulatory Networks that Suppress Ras-Sensitized Epithelial Cell Proliferation.

TLK2 TLK1

3.53e-053120228535374
Pubmed

Novel Therapeutics in Acute Myeloid Leukemia.

FLT3 IDH1

3.53e-053120228561688
Pubmed

Tissue kallikrein is essential for invasive capacity of circulating proangiogenic cells.

KLK3 KLK2

3.53e-053120221164105
Pubmed

Tissue kallikrein stimulates Ca(2+) reabsorption via PKC-dependent plasma membrane accumulation of TRPV5.

KLK3 KLK2

3.53e-053120217006539
Pubmed

Characterization of mouse glandular kallikrein 24 expressed in testicular Leydig cells.

KLK3 KLK2

3.53e-053120215985384
Pubmed

Characterization of androgen receptor and nuclear receptor co-regulator expression in human breast cancer cell lines exhibiting differential regulation of kallikreins 2 and 3.

KLK3 KLK2

3.53e-053120212124798
Pubmed

Porcine kallikrein gene family: genomic structure, mapping, and differential expression analysis.

KLK3 KLK2

3.53e-053120217210241
Pubmed

Spatially- and temporally-restricted expression of meltrin alpha (ADAM12) and beta (ADAM19) in mouse embryo.

ADAM19 ADAM12

3.53e-05312029622634
Pubmed

Detection of a kallikrein in the mouse lactating mammary gland: a possible processing enzyme for the epidermal growth factor precursor.

KLK3 KLK2

3.53e-05312027525260
Pubmed

Identification of mK1, a true tissue (glandular) kallikrein of mouse submandibular gland: tissue distribution and a comparison of kinin-releasing activity with other submandibular kallikreins.

KLK3 KLK2

3.53e-05312028188620
Pubmed

Mouse testicular Leydig cells express Klk21, a tissue kallikrein that cleaves fibronectin and IGF-binding protein-3.

KLK3 KLK2

3.53e-053120211606460
Pubmed

The amino acid sequence of the gamma-subunit of mouse submaxillary gland 7 S nerve growth factor.

KLK3 KLK2

3.53e-05312027263706
Pubmed

A cytocidal tissue kallikrein isolated from mouse submandibular glands.

KLK3 KLK2

3.53e-05312022583286
Pubmed

Inducible expression of kallikrein in renal tubular cells protects mice against spontaneous lupus nephritis.

KLK3 KLK2

3.53e-053120223280471
Pubmed

Mouse glandular kallikrein genes. Nucleotide sequence of cloned cDNA coding for a member of the kallikrein arginyl esteropeptidase group of serine proteases.

KLK3 KLK2

3.53e-05312026174512
Pubmed

Protease-activated receptor dependent and independent signaling by kallikreins 1 and 6 in CNS neuron and astroglial cell lines.

KLK3 KLK2

3.53e-053120218778305
Pubmed

Single-chain tissue-type plasminogen activator is a substrate of mouse glandular kallikrein 24.

KLK3 KLK2

3.53e-053120216286722
Pubmed

mGK-6-derived true tissue kallikrein is synthesized, processed, and targeted through a regulated secretory pathway in mouse pituitary AtT-20 cells.

KLK3 KLK2

3.53e-05312021639762
Pubmed

PTEN, ATM, IDH1 mutations and MAPK pathway activation as modulators of PFS and OS in patients treated by first line EGFR TKI, an ancillary study of the French Cooperative Thoracic Intergroup (IFCT) Biomarkers France project.

IDH1 ATM

3.53e-053120233248711
Pubmed

Serendipitous Discovery of T Cell-Produced KLK1b22 as a Regulator of Systemic Metabolism.

KLK3 KLK2

3.53e-053120237358498
Pubmed

Deletion of kallikrein 1b5 (Klk1b5) has no impact on fertility in mice.

KLK3 KLK2

3.53e-053120230957940
Pubmed

Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation.

KLK3 KLK2

3.53e-053120225628066
Pubmed

Cloning and initial characterization of mouse meltrin beta and analysis of the expression of four metalloprotease-disintegrins in bone cells.

ADAM19 ADAM12

3.53e-05312029461614
Pubmed

Targeting kallikrein 6 proteolysis attenuates CNS inflammatory disease.

KLK3 KLK2

3.53e-053120215033932
Pubmed

Cellular basis for the differential response of mouse kallikrein genes to hormonal induction.

KLK3 KLK2

3.53e-05312023649290
Pubmed

Kallikrein-related peptidases.

KLK3 KLK2

3.53e-053120218344018
Pubmed

Positive selection shaped the convergent evolution of independently expanded kallikrein subfamilies expressed in mouse and rat saliva proteomes.

KLK3 KLK2

3.53e-053120221695125
Pubmed

Uterine artery structural and functional changes during pregnancy in tissue kallikrein-deficient mice.

KLK3 KLK2

3.53e-053120212933530
Pubmed

The lupus-susceptibility gene kallikrein downmodulates antibody-mediated glomerulonephritis.

KLK3 KLK2

3.53e-053120219262577
Pubmed

Renin and kallikrein in connecting tubule of mouse.

KLK3 KLK2

3.53e-053120214633138
Pubmed

Sequence of mGK-11, a mouse glandular kallikrein gene.

KLK3 KLK2

3.53e-05312023205728
Pubmed

Structure of mouse kallikrein gene family suggests a role in specific processing of biologically active peptides.

KLK3 KLK2

3.53e-05312026602295
Pubmed

A metalloprotease-disintegrin participating in myoblast fusion.

ADAM19 ADAM12

3.53e-05312027566181
Pubmed

A complete cDNA sequence for the major epidermal growth factor binding protein in the male mouse submandibular gland.

KLK3 KLK2

3.53e-05312023322386
Pubmed

Teashirt 3 expression in the chick embryo reveals a remarkable association with tendon development.

TSHZ3 TSHZ2

3.53e-053120216631416
Pubmed

beta-NGF-endopeptidase: structure and activity of a kallikrein encoded by the gene mGK-22.

KLK3 KLK2

3.53e-05312022012805
Pubmed

Kallikrein protects against microalbuminuria in experimental type I diabetes.

KLK3 KLK2

3.53e-053120219516248
Pubmed

Autoimmunity against a tissue kallikrein in IQI/Jic Mice: a model for Sjogren's syndrome.

KLK3 KLK2

3.53e-053120215545270
Pubmed

Sequence and expression of mouse gamma-renin.

KLK3 KLK2

3.53e-05312023288617
Pubmed

The prognostic significance of IDH1 mutations in younger adult patients with acute myeloid leukemia is dependent on FLT3/ITD status.

FLT3 IDH1

3.53e-053120220651067
Pubmed

Analysis of TSHZ2 and TSHZ3 genes in congenital pelvi-ureteric junction obstruction.

TSHZ3 TSHZ2

3.53e-053120219745106
Pubmed

Sequence of an epidermal growth factor-binding protein.

KLK3 KLK2

3.53e-05312026330081
Pubmed

Cloning and characterization of mouse klk27, a novel tissue kallikrein expressed in testicular Leydig cells and exhibiting chymotrypsin-like specificity.

KLK3 KLK2

3.53e-053120211082197
Pubmed

Mouse glandular kallikrein genes. Identification, structure, and expression of the renal kallikrein gene.

KLK3 KLK2

3.53e-05312023007510
Pubmed

Role of tissue kallikrein in response to flow in mouse resistance arteries.

KLK3 KLK2

3.53e-053120215126916
Pubmed

The molecular biology of the kallikrein-kinin system: I. General description, nomenclature and the mouse gene family.

KLK3 KLK2

3.53e-05312028228186
Pubmed

The sequence of a cDNA clone coding for a novel kallikrein from mouse submaxillary gland.

KLK3 KLK2

3.53e-05312023636812
Pubmed

Reduction in nerve growth factor availability leads to a conditioning lesion-like effect in sympathetic neurons.

KLK3 KLK2

3.53e-053120216967509
Pubmed

Growth factor-binding proteases in the murine submaxillary gland: isolation of a cDNA clone.

KLK3 KLK2

3.53e-053120211892812
Pubmed

Cardiovascular abnormalities with normal blood pressure in tissue kallikrein-deficient mice.

KLK3 KLK2

3.53e-053120211226291
Pubmed

Sequence of the mouse glandular kallikrein gene, mGK-5.

KLK3 KLK2

3.53e-05312023502721
Pubmed

Kallikrein 6 regulates early CNS demyelination in a viral model of multiple sclerosis.

KLK3 KLK2

3.53e-053120222335454
Pubmed

DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation.

UBE3C DOT1L

3.53e-053120234551297
Pubmed

Isolation of a cDNA clone coding for the gamma-subunit of mouse nerve growth factor using a high-stringency selection procedure.

KLK3 KLK2

3.53e-05312026548955
Pubmed

Interference of kallikrein 1b26 (klk1b26) translation by microRNA specifically expressed in female mouse submandibular glands: an additional mechanism for sexual dimorphism of klk1b26 protein in the glands.

KLK3 KLK2

3.53e-053120222085651
Pubmed

Sites of glandular kallikrein gene expression in fetal mice.

KLK3 KLK2

3.53e-05312021334010
Pubmed

The TLK-ASF1 histone chaperone pathway plays a critical role in IL-1β-mediated AML progression.

TLK2 TLK1

3.53e-053120238498025
Pubmed

Tissue kallikrein deficiency and renovascular hypertension in the mouse.

KLK3 KLK2

3.53e-053120219244588
Pubmed

Differences in substrate and inhibitor sequence specificity of human, mouse and rat tissue kallikreins.

KLK3 KLK2

3.53e-053120215040788
Pubmed

ATM/G6PD-driven redox metabolism promotes FLT3 inhibitor resistance in acute myeloid leukemia.

FLT3 ATM

3.53e-053120227791036
Pubmed

Clinical characteristics and outcomes in patients with acute myeloid leukemia with concurrent FLT3-ITD and IDH mutations.

FLT3 IDH1

3.53e-053120233119202
Pubmed

Genetic deficiency in tissue kallikrein activity in mouse and man: effect on arteries, heart and kidney.

KLK3 KLK2

3.53e-053120218627303
Pubmed

Tissue kallikrein is required for the cardioprotective effect of cyclosporin A in myocardial ischemia in the mouse.

KLK3 KLK2

3.53e-053120225623731
Pubmed

Estrogen-dependent expression of the tissue kallikrein gene (Klk1) in the mouse uterus and its implications for endometrial tissue growth.

KLK3 KLK2

3.53e-053120217219431
InteractionCALM3 interactions

FLT3 PNN MYO5B MYO9B TNIP2 KIF1B UBR4 NSMF ASPM KCNN1 UBE3C IQCE

7.55e-0734311712int:CALM3
InteractionCALM2 interactions

MYO9B TNIP2 KIF1B UBR4 NSMF ASPM KCNN1 UBE3C IQCE

3.26e-062061179int:CALM2
InteractionCALM1 interactions

MYO5B MYO9B KIF1B UBR4 OBSCN IDH1 DMXL1 GRAMD1B NSMF PRIM1 ASPM KCNN1 UBE3C IQCE

1.63e-0562611714int:CALM1
GeneFamilyPlexins

PLXND1 PLXNA1

5.68e-049732683
GeneFamilyZinc fingers C2H2-type|ZF class homeoboxes and pseudogenes

TSHZ3 TSHZ2

1.63e-0315732529
GeneFamilyKallikreins

KLK3 KLK2

1.86e-0316732616
CoexpressionZHENG_BOUND_BY_FOXP3

FLT3 RAPGEF6 ADAM19 TBC1D30 IRF2 CHD2 HEATR5A IDH1 JMJD1C CYTIP TLK1 MACF1

3.19e-0649812012M1741
CoexpressionZHENG_BOUND_BY_FOXP3

FLT3 RAPGEF6 ADAM19 TBC1D30 IRF2 CHD2 HEATR5A IDH1 JMJD1C CYTIP TLK1 MACF1

3.83e-0650712012MM1030
CoexpressionAtlasDevelopingGonad_e14.5_ epididymis_emap-29141_k-means-cluster#3_top-relative-expression-ranked_1000

TLK2 KIF1B CHD2 CHIC1 JMJD1C DMXL1 TLK1 ASPM MMP16

1.78e-052751149gudmap_developingGonad_e14.5_ epididymis_1000_k3
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#5_top-relative-expression-ranked_200

TLK2 CHIC1 DMXL1 ASPM MMP16

3.49e-05691145gudmap_developingGonad_e11.5_ovary + mesonephros_k5_200
CoexpressionAtlasDevelopingGonad_e11.5_ovary + mesonephros_emap-3226_k-means-cluster#4_top-relative-expression-ranked_500

TLK2 KIF1B CHD2 CHIC1 DMXL1 ASPM MMP16

4.02e-051721147gudmap_developingGonad_e11.5_ovary + mesonephros_k4_500
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Oligoastrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

ARRDC1 KIF1B UBR4 HEATR5A CCDC178 JMJD1C NFRKB

7.48e-0813511873351e8b9e417397c5fa9f856184ff24ce1a27242
ToppCell10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8|Liver / Manually curated celltypes from each tissue

RAPGEF6 ADAM19 TSHZ2 CHD2 JMJD1C MACF1 ATM

5.49e-071811187f2315414e714ac86211546a935660c4be6e85f1b
ToppCelldroplet-Spleen-nan-18m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO48 NSD2 LIG1 PRIM1 ASPM ESPL1 NYAP1

7.61e-071901187b99271d139c8d01e20feb95d99f79c9b2756b4cb
ToppCellmild|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TLK2 PNN CHD2 JMJD1C OASL MACF1 ATM

1.07e-06200118712f1685ce8f218433068e090c9d839cd5a1910bf
ToppCellTCGA-Brain-Primary_Tumor-Low_Grade_Glioma-Astrocytoma-3|TCGA-Brain / Sample_Type by Project: Shred V9

UBR4 HEATR5A CCDC178 JMJD1C NFRKB MMP16

2.90e-061491186768877bade04ca0321593b8470b5011ad8270431
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Mesenchymal-Fibroblast-kidney_interstitial_fibroblast-Adaptive_/_Maladaptive_/_Repairing_Fibroblast|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

TSHZ3 TSHZ2 COLGALT2 LINC01553 DMD MMP16

7.30e-061751186795a6564d5a75ffd35d39f5274b9e8d28708bbc8
ToppCellMid-temporal_gyrus_(MTG)|World / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

PNN TSHZ2 ANKRD30B HRH1 DMD PLXNA1

8.05e-061781186ad187db4c40b9078d54dd915c143e0172b2f47b8
ToppCelldroplet-Spleen-nan-3m|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL24 RPL32 PNN JMJD1C DMXL1 MACF1

1.03e-05186118626f1e9930adf2fe4af0819e56f69915bd8330e4a
ToppCelldroplet-Spleen-nan-3m-Lymphocytic|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL24 RPL32 PNN CHD2 DMXL1 MACF1

1.07e-05187118691c8e93bde0d1d1a4e324b0acf2afda00f4fb3bf
ToppCelldroplet-Spleen-nan-3m-Lymphocytic-nan|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RPL24 RPL32 PNN CHD2 DMXL1 MACF1

1.07e-051871186382db691eb0b3e089e816bed3d6699cc2d4e1bda
ToppCelldroplet-Spleen-SPLEEN-30m-Lymphocytic-immature_NKT_cell|Spleen / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NSD2 LIG1 WDHD1 PRIM1 ASPM ESPL1

1.20e-051911186c8b99bd3a30c81ee4deba9cbf0196920ab3ab550
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC TSHZ2 COLGALT2 DSEL MMP16 PDZRN3

1.24e-0519211868d56e360ebc624ca4cd7f0af4f3cc599c244f134
ToppCell10x5'-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RAPGEF6 TSHZ2 CHD2 JMJD1C MACF1 ATM

1.24e-05192118647646d7e4990be85072987f92bf18d52f8da752e
ToppCell3'-GW_trimst-1.5-LargeIntestine-Mesenchymal-fibroblastic|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

BOC RPL24 TSHZ2 ADAM12 VSTM4 MMP16

1.27e-05193118668089ba4123e2f9bea9aae0023a844b5a57bfc0e
ToppCellTCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Colon_Adenocarcinoma-10|TCGA-Colorectal / Sample_Type by Project: Shred V9

BOC TSHZ3 P4HA3 ADAM12 VSTM4 A4GALT

1.27e-051931186194e7fa00a50cc4e026987b715323d125d79594e
ToppCellFetal_29-31_weeks-Mesenchymal-matrix_fibroblast_2_cell-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

BOC TSHZ2 COLGALT2 DSEL MMP16 PDZRN3

1.31e-051941186439d3f17c1f4736122b330e98add9292c7036a8e
ToppCellCOVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi|lung / Disease (COVID-19 only), tissue and cell type

FLT3 ATG7 MYO9B AOAH CYTIP GRAMD1B

1.43e-0519711863896729740d151f0eb845f1961c7b969bfbdd28d
ToppCellmild-low-quality_cells|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

TLK2 PNN CHD2 ABCA5 MACF1 ATM

1.52e-051991186f0b0097df0026496470a80d8cc9375ffd8389b00
ToppCellParenchymal-NucSeq-Immune_Lymphocytic-T-T_CD4-CD4|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

ADAM19 AOAH ADAM12 CYTIP GRAMD1B IL23R

1.52e-051991186fbdde57dd88656621801e65ee2818251588f3874
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3|Severe / Location, Disease Group, Cell group, Cell class (2021.03.09)

TSHZ2 P4HA3 ADAM12 DSEL CTSK PDZRN3

1.56e-052001186e663995fc44c340d878d66b278b7b5c2ff784301
ToppCellLung_Parenchyma-Severe-Mesenchymal-Mesenchymal-Fibroblasts-3-|Severe / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

TSHZ2 P4HA3 ADAM12 DSEL CTSK PDZRN3

1.56e-0520011862cb8a39a12522a9643c6244d5e94cb4559868bb9
ToppCellParenchyma_COVID-19-Stromal-TX-Fibroblasts-3|Parenchyma_COVID-19 / Sample group, Lineage and Cell type

TSHZ2 P4HA3 ADAM12 DSEL CTSK PDZRN3

1.56e-0520011868cc5057b0e5ae9b72ea40d2ffbc52b79bf87ccef
ToppCell343B-Lymphocytic-NK_cells-NK_cell_D|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

KIF13B TSHZ2 CCDC190 MMAA

2.86e-0566118457fd31a25addc48793d7975eadccf4c5a41a8b03
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW09-Macroglial-Astrocyte|GW09 / Sample Type, Dataset, Time_group, and Cell type.

BOC IRF2 CCDC178 CYTIP ABCC2

3.83e-05142118585e573616e54d41391b4ad8c3d38e4ca92112673
ToppCell343B-Myeloid-Macrophage-SPP1+_Macrophage_2|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

CHIC1 CYTIP VSTM4 NFRKB HRH1

4.98e-051501185744050a1b665c6989f37141348af3df7579a73c9
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-T_CD4/CD8|Lung / Manually curated celltypes from each tissue

TSHZ2 OBSCN CHD2 MACF1 BRD1

5.14e-051511185999c11d19b61d6b130ad5e623afa83cbdfe13cdd
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_VISp_Hsd11b1_Endou|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BOC RPH3AL PLXND1 NEUROD6 PDZRN3

6.37e-051581185c8af8964a140acb2987e3b4906d72c546108d229
ToppCellPosterior_cortex|World / BrainAtlas - Mouse McCarroll V32

TSHZ3 ADAM12 HRH1 NEUROD6 PDZRN3

6.56e-05159118518e9fe2efbe0bca7c3990f3b12b6f549e2c1263a
ToppCellFLU-Healthy-1|Healthy / Virus stimulation, Condition and Cluster

IRF2 OASL CPNE1 PLXNA1 IL23R

6.56e-05159118597c8e16a7ac10ebba96daee97f9fb1d4a404f23b
ToppCellFLU-Healthy-1|FLU / Virus stimulation, Condition and Cluster

IRF2 OASL CPNE1 PLXNA1 IL23R

6.56e-051591185fe2a9f79b058e89214256e736f6e266830cdfa28
ToppCellICU-NoSEP-Lymphocyte-T_NK-Treg|ICU-NoSEP / Disease, Lineage and Cell Type

RAPGEF6 TSHZ2 ADAM12 C3orf33 ABCC2

6.56e-051591185d065ec02a4f3672ba53d4fea66029f1ce68f367f
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT-L5_IT_ALM_Cbln4_Fezf2|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BOC ADAM12 HRH1 NEUROD6 PDZRN3

6.76e-051601185d8241404d775f9a709abdf17988f36293fcf4c58
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

MBTD1 FLT3 OBSCN CYTIP HRH1

6.76e-051601185237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

TSHZ3 FLT3 CCDC190 CYB5R3 LRRCC1

8.05e-0516611856210a136efb99d70c2026b6454363f1bd2723558
ToppCellCV-Mild-3|Mild / Virus stimulation, Condition and Cluster

TSHZ2 ASCC1 GRAMD1B LIG1 WDHD1

8.05e-0516611855599f90fc0e15a3670b03187085eba91228390a2
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c04-COTL1|Severe-critical_progression_d12-22 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TSHZ3 PNN NSD2 CCDC83 DSEL

8.28e-0516711853b717d33aaf1ef0869cc4bca8432ba8008875cc5
ToppCellfrontal_cortex-Neuronal-glutamatergic_neuron-L5_IT|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

BOC PLXND1 ADAM12 NEUROD6 PDZRN3

8.28e-051671185f1ce6e64ebede1f3ef36fe982f46919fd1f814dd
ToppCellTCGA-Lung-Primary_Tumor-Lung_Carcinoma-Lung_Squamous_Cell_Carcinoma-4|TCGA-Lung / Sample_Type by Project: Shred V9

ADAM19 P4HA3 ADAM12 CTSK PDZRN3

8.51e-051681185aefea14b8b1c1b6a05f827effd22ba15274fddc9
ToppCellE18.5-Mesenchymal-Mesenchymal_structural-Fibroblastic-PMP-PMP_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

CEP162 ADAM12 ESPL1 MMP16 CTSK

8.75e-0516911857cb1b87be66a22fe5731bb1b55bc515920fe3e8b
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-6|TCGA-Liver / Sample_Type by Project: Shred V9

BOC TSHZ3 P4HA3 CTSK PDZRN3

8.75e-051691185e992530776cab922d0360b275fb9cb8bd0017b06
ToppCellImmune-dendritic_cell|World / Lineage, Cell type, age group and donor

FLT3 ADAM19 RGS7 CYTIP GRAMD1B

9.25e-0517111856a9e2e2d3e1d8cc475bf9765129bc4a32da3b8ea
ToppCell3'_v3-lymph-node_spleen-Lymphocytic_T_CD4-T_CD4/CD8|lymph-node_spleen / Manually curated celltypes from each tissue

RAPGEF6 CHD2 JMJD1C MACF1 ATM

9.25e-0517111852e9a20f8980b78325c52065a9c14ab3656267c05
ToppCellBrain_organoid-organoid_Tanaka_cellReport-5w-Mesenchymal-Cilia-bearing_cell|5w / Sample Type, Dataset, Time_group, and Cell type.

BOC MBTD1 COLGALT2 TEX10 CTSK

9.77e-051731185d4cbeae262abfa30d8c5452285d3261a96875610
ToppCellPND14-Immune-Immune_Myeloid-DC-cDC1-cDC1_prolif|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FLT3 NSD2 LIG1 CPNE1 DSEL

1.00e-04174118509b091e24317c3f7bac043f04762a533e30793de
ToppCellnormal_Lymph_Node-Myeloid_cells-pDCs|Myeloid_cells / Location, Cell class and cell subclass

ADAM19 RGS7 ABCA5 USP32 S100PBP

1.00e-0417411852274648b80dd74f3c948a779bba3391095964c34
ToppCelldroplet-Heart-nan-3m|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KIF13B PNN JMJD1C MACF1 DMD

1.06e-041761185749b47eac5436fa34e0d243ffbc6f1897f4e431e
ToppCellPND07-Mesenchymal-Mesenchymal_structural-Fibroblastic-AF1-AF1_prolif|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

VSTM4 LIG1 WDHD1 PRIM1 MACF1

1.06e-041761185cb8fd56a4f935cdda19d7ab43382cdda7c307667
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC P4HA3 LIG1 KATNIP DNAI7

1.12e-0417811856178706db4a855d72abc156537604d575624df56
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Epithelial-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

BOC P4HA3 LIG1 KATNIP DNAI7

1.12e-041781185f02076ece0fa899e620971c887ad4da7f48684ed
ToppCell3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.0.5|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHZ2 NSD2 MUC16 CHD2 MACF1

1.15e-0417911856e965e424eebef50f0202cff75f458be395cfca1
ToppCellnormal_Lymph_Node-Myeloid_cells-CD141+_DCs|normal_Lymph_Node / Location, Cell class and cell subclass

TSHZ3 FLT3 AOAH CYB5R3 LRRCC1

1.15e-041791185ec995ccd6e1dbd06287ad836c232d9aed1cf94a8
ToppCellPND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-EPC|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

NSD2 LIG1 WDHD1 ASPM ESPL1

1.15e-04179118554191c00b29f53b520cd3243b5791daa4a2c72d7
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell_cycling-Cycling_Proximal_Tubule_Epithelial_Cell_S-high|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

NSD2 LIG1 WDHD1 DOT1L ESPL1

1.15e-04179118588d44b04eb5c079531db663ed98ddb20b60feb9a
ToppCellnormal_Pleural_Fluid-Myeloid_cells-CD141+_DCs|Myeloid_cells / Location, Cell class and cell subclass

FLT3 ADAM19 CYB5R3 LRRCC1 DMD

1.18e-041801185a0b35067b6f2dbd8145da8bab760e9f650f045b0
ToppCellControl-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

BOC TSHZ2 VSTM4 DMD PDZRN3

1.27e-0418311857eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCellwk_20-22-Mesenchymal-Chondrocyte-intermediate_chondrocyte|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

MBTD1 LIG1 POC1B MRPL3 FAM110B

1.27e-0418311851464b5c4425e8776c4aeb4d2b560481d4bf13931
ToppCelldroplet-Lung-immune-endo-depleted-3m-Myeloid-Proliferating_Alveolar_Macrophage|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

FBXO48 NSD2 WDHD1 ASPM CTSK

1.27e-04183118542dc31d587fbb9724b2f0be5ee8ed77233f67b86
ToppCellAdult-Mesenchymal-matrix_fibroblast_2_cell-D122|Adult / Lineage, Cell type, age group and donor

BOC TSHZ2 COLGALT2 MMP16 PDZRN3

1.30e-0418411852b7e6f91e11c228f0521e099886867d9e998e78d
ToppCellTCGA-Bladder-Primary_Tumor-Urothelial_Carcinoma-Non-Papillary_Muscle_Invasive_Urothelial_Carcinoma-4|TCGA-Bladder / Sample_Type by Project: Shred V9

BOC P4HA3 ADAM12 CTSK PDZRN3

1.34e-041851185e1f3f0e974eb3fe1c05018beb9e124c7fb0cbe50
ToppCellCiliated_cells-B-Myositis-ILD_01|World / lung cells shred on cell class, cell subclass, sample id

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.34e-041851185f012c243343e1d1956db19b34d062e9b13de2b2a
ToppCell3'-Pediatric_IBD-SmallIntestine-Hematopoietic-T_cells-Th1|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ADAM19 ADAM12 GRAMD1B ASPM IL23R

1.34e-041851185326c8b6ea0e9140616d7b867db1385b980dc3678
ToppCell3'_v3-Lung-Lymphocytic_T_CD4-Tnaive/CM_CD4|Lung / Manually curated celltypes from each tissue

RPL24 RPL32 RAPGEF6 TSHZ2 CYTIP

1.37e-041861185c67f373ba60e8d1ab70dfacc711ee440eaff6fb3
ToppCellControl-Fibroblasts-Other_FB|Control / group, cell type (main and fine annotations)

BOC TSHZ2 DMD MMP16 PDZRN3

1.41e-041871185bd3739c4a52aa1ba5deffd778e113a9800f7e158
ToppCellTCGA-Breast-Primary_Tumor-Breast_Carcinoma-Infiltrating_Ductal_Carcinoma-6|TCGA-Breast / Sample_Type by Project: Shred V9

TSHZ3 P4HA3 ADAM12 VSTM4 CTSK

1.41e-041871185a96495803ba13fcfadd1d83b3cf5774f3fed0a20
ToppCell3'_v3-blood|World / Manually curated celltypes from each tissue

RPL24 FLT3 PNN TSHZ2 BRD1

1.41e-0418711859e70e8d7cd8ae517ddf5fd56c69ec16fc33ddff5
ToppCellBronchial-NucSeq-Immune_Lymphocytic-T-T_CD8-MAIT|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

FBXO48 RPL32 AOAH CYTIP IL23R

1.48e-041891185159b0979c93b7d98aaeeb43fba5983a9f67b9c9d
ToppCellwk_15-18-Mesenchymal-Fibroblast-Airway_fibro|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

BOC VSTM4 A4GALT CTSK PDZRN3

1.48e-0418911854f9608b84d135268a17455661870c46ae8554a24
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 CCDC190 VSTM4 CTSK PDZRN3

1.52e-0419011858cb950effc449ae59a915132ecc079be54d1acfe
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 CCDC190 VSTM4 CTSK PDZRN3

1.52e-0419011855dfbd064ab1f8a0b18b5975c47f8e79697f3db15
ToppCelldroplet-Pancreas-Exocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 CCDC190 VSTM4 CTSK PDZRN3

1.52e-04190118517a73a658fb30a4322b31e38db7b240023738f29
ToppCellT_cells-Effector_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

ADAM19 PLXND1 ARHGAP35 ADAM12 IL23R

1.52e-0419011851af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCellpdx-Tumor_cells-T1|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)

NSD2 WDHD1 PRIM1 ASPM ESPL1

1.52e-041901185d06ee5f89f1cec8db6897fe3b2a890a07cd3697b
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-0419111857b5da29109aa28768c67653a1bc0f385c2d2269b
ToppCelldroplet-Lung-LUNG-30m-Lymphocytic-Proliferating_T|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADAM19 NSD2 LIG1 PRIM1 ASPM

1.55e-041911185239300ff76f2c855b2b04d3002461158be90a01b
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL24 RPL32 RAPGEF6 TSHZ2 ATM

1.55e-041911185f398344aaa79fc93d792e241b634a6afe4aff33d
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-0419111859f19098f260d5542aa8ba7eb6f91b44d0db6e0a4
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185fa9f8b50bfc7911c858bc2f9dcd204873d97ac61
ToppCellAdult-Immune-T_lymphocyte-D175|Adult / Lineage, Cell type, age group and donor

ADAM19 TSHZ2 ADAM12 CYTIP IL23R

1.55e-0419111850b84fd1dc68146d9f72422b102744d2847f5ecb2
ToppCellControl-Epithelial-Ciliated_cells|Control / Condition, Lineage and Cell class

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185ea1d2c6838119b7019e9a2ff71d6212262b51b57
ToppCellCD8+_Memory_T_cell-CV-7|CD8+_Memory_T_cell / cell class, Virus stimulation and cluster

KIF13B ADAM19 PNN MACF1 TMEM68

1.55e-0419111859454f642c3621370fa23640b631301346b300950
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated-|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185b4e335e798c9617356b8e24412f9270c42dce656
ToppCellBAL-Control-Epithelial-Epithelial-Ciliated|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185c4b223b33c020a064f576711a3d700eb60a2d737
ToppCellBAL-Control-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-0419111855129f778a9283bfac4ff322c21c5ca71da4b7174
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185df8a1a6e78aa0cb941b94cb676bd6891d79f3687
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL24 RPL32 RAPGEF6 TSHZ2 ATM

1.55e-04191118511da47d96f44ba629e3299667495e7daddbbe86c
ToppCellControl-Epithelial|Control / Disease group,lineage and cell class （2021.01.30）

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185b78547dae8328244a47c83346447bdd787efbcae
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

RPL24 RPL32 RAPGEF6 TSHZ2 ATM

1.55e-041911185ffcb2c8dbcf40281b439f4b719b5b341972ffb9a
ToppCellBAL-Control-Epithelial-Epithelial|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185c50d6a1a6209ed4157f7c00fc24d4ecb43790f44
ToppCellControl-Epithelial-Ciliated|Control / Disease group,lineage and cell class （2021.01.30）

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-041911185cdc08e95a0c8f5c7a8d01b6bbaafdb54ef2f0d12
ToppCellControl-Epithelial|Control / Condition, Lineage and Cell class

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.55e-0419111856228302febdb3dffe37dece7062d27ac9ccc6d4b
ToppCellPBMC-Convalescent-Lymphocyte-T/NK-CD4+_T-CD4+_T_naive-|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

RPL24 RPL32 RAPGEF6 TSHZ2 ATM

1.55e-041911185ffe88d1ad676c745c76db89f766062fd365329f4
ToppCellILEUM-non-inflamed-(1)_T_cell-(1)_TFH-like|(1)_T_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

RPL24 RPL32 TSHZ2 TLK1 ATM

1.59e-0419211850f9cae41bb9bc9366efe9eb48e26b3e80c642879
ToppCellCOVID_non-vent-Lymphocytic-T_cell-CD4+_T_cell_(ISG_high)|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

RPL24 RPL32 RAPGEF6 TSHZ2 ATM

1.59e-04192118535557254738844c27ffcd00f3287fbcc0a4d0f3b
ToppCellCOVID-19_Convalescent-Lymphoid_T/NK-CD4+_T_naive|COVID-19_Convalescent / Disease group, lineage and cell class

RPL24 RPL32 RAPGEF6 TSHZ2 ATM

1.59e-041921185ad7207810116e73d461242e42071901b6a9f48c6
ToppCellH1299-infected|H1299 / Cell line, Condition and Strain

PNN NSD2 CHD2 ASPM ESPL1

1.59e-0419211859cf8049bdc3e0f81ce69042beac72b08d8f38b4e
ToppCellmoderate-Lymphoid-Treg|moderate / Severity, Lineage and Cell class of Nasopharyngeal (NS) Samples from Patients and Controls

ADAM19 ADAM12 CYTIP ATM IL23R

1.59e-041921185e370ff5aaff7b7042ba9aaf93de43aa563b8b9f9
ToppCell10x3'2.3-week_12-13-Lymphocytic_T-T_NK-CD4_T_cell|week_12-13 / cell types per 3 fetal stages;per 3',per 5'

RPL24 RPL32 RAB25 CYTIP ATM

1.59e-04192118528d6b159e29e6c45f3f27589bf981bab8e97068e
ToppCellChildren_(3_yrs)-Mesenchymal-matrix_fibroblast_2_cell-D046|Children_(3_yrs) / Lineage, Cell type, age group and donor

BOC TSHZ2 COLGALT2 MMP16 PDZRN3

1.59e-041921185e0f4e4470a71bfa81d9dcd8594e5f82aafc24f81
ToppCell15-Trachea-Epithelial-Intermediate_ciliated|Trachea / Age, Tissue, Lineage and Cell class

ANKUB1 CCDC190 MUC16 VWA3B DNAI7

1.59e-0419211859cbe961a800c981cdc742a47ed18e9c8eb6430bd
ToppCellMesenchymal-matrix_fibroblast_2_cell|World / Lineage, Cell type, age group and donor

BOC TSHZ2 COLGALT2 MMP16 PDZRN3

1.59e-041921185a769158c49d2b208c4224d85e7ae68c85cc372ed
DiseaseAdenoid Cystic Carcinoma

JMJD1C TLK1 ASPM ATM BRD1 ESPL1

2.86e-061001166C0010606
DiseaseColorectal Carcinoma

BOC ADAM19 OBSCN IDH1 VSTM4 LIG1 ABCA5 HRH1 DMD ABCC2 DSEL FAM110B

2.16e-0570211612C0009402
Diseaselactosyl-N-behenoyl-sphingosine (d18:1/22:0) measurement

A4GALT CYB5R3

9.15e-0541162EFO_0800518
Diseaselactosylceramide 4-alpha-galactosyltransferase measurement

A4GALT CYB5R3

1.52e-0451162EFO_0802683
Diseasegamma-aminobutyric acid receptor-associated protein-like 1 measurement

ATG7 HRH1

1.52e-0451162EFO_0801613
Diseasehemoglobin A1 measurement

TSHZ3 MYO9B PLXND1 JMJD1C VSTM4 A4GALT CYB5R3 MACF1 UBE3C

2.20e-045201169EFO_0007629
Diseaseduodenal ulcer

FLT3 TTLL8 CNGA4

3.85e-04361163EFO_0004607
DiseaseNeoplasm Recurrence, Local

IDH1 KLK3 TLK1

4.88e-04391163C0027643
Diseasesphingolipid measurement

RRP7BP A4GALT CYB5R3

5.26e-04401163EFO_0004622
Diseaselactosyl-N-nervonoyl-sphingosine (d18:1/24:1) measurement

A4GALT CYB5R3

5.42e-0491162EFO_0800517
Diseaseceliac disease (is_implicated_in)

MYO9B IL23R

6.75e-04101162DOID:10608 (is_implicated_in)
Diseaseblood cobalt measurement

TSHZ2 AOAH MUC16 RGS7

6.90e-041011164EFO_0007577
Diseasenucleus accumbens volume change measurement

MUC16 NEUROD6

8.23e-04111162EFO_0021493
DiseaseGastrointestinal Stromal Sarcoma

BOC RPL24 DMD

8.46e-04471163C3179349
Diseasenervous system disease (implicated_via_orthology)

ATG7 KIF1B

9.86e-04121162DOID:863 (implicated_via_orthology)
DiseaseGastrointestinal Stromal Tumors

BOC RPL24 DMD

1.01e-03501163C0238198
DiseaseL2 Acute Lymphoblastic Leukemia

FLT3 NSD2 IDH1

1.01e-03501163C0023453
DiseaseChildhood Acute Lymphoblastic Leukemia

FLT3 NSD2 IDH1

1.14e-03521163C0023452
Diseaseinterleukin 1 receptor antagonist measurement

A4GALT CYB5R3 UBE3C

1.20e-03531163EFO_0004754
DiseasePrecursor Cell Lymphoblastic Leukemia Lymphoma

FLT3 NSD2 IDH1

1.80e-03611163C1961102
Diseaseresponse to opioid

MUC16 ADAM12 USP32

1.80e-03611163EFO_0008541
DiseaseMuscle hypotonia

NSD2 ASCC1

2.00e-03171162C0026827
Diseasemean platelet volume

ADAM19 MYO9B KIF1B PLXND1 JMJD1C GRAMD1B TLK1 A4GALT CYB5R3 BRD1 ESPL1

2.31e-03102011611EFO_0004584
Diseaseleukemia (implicated_via_orthology)

ATM DOT1L

2.51e-03191162DOID:1240 (implicated_via_orthology)
Diseasepentachlorophenol measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022071
Diseaseparathion measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022070
Diseasepotassium chromate measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022072
Diseasemercuric chloride measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022068
Diseaseheptachlor epoxide measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022067
Diseasemethoxychlor measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022069
Disease4,6-dinitro-o-cresol measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022053
Disease2,4,5-trichlorophenol measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022052
Diseaseazinphos methyl measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022055
Diseasealdrin measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022054
Diseasedicofol measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022060
Diseasedisulfoton measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022062
Diseasedieldrin measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022061
Diseaseendrin measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022064
Diseaseendosulfan measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022063
Diseaseheptachlor measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022066
Diseaseethion measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022065
Diseasechlorpyrifos measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022057
Diseasecadmium chloride measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022056
Diseasediazinon measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022059
Diseasedibutyl phthalate measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0022058
Diseaseenvironmental exposure measurement

TSHZ2 MUC16 RGS7

3.01e-03731163EFO_0008360
DiseaseDDT metabolite measurement

TSHZ2 MUC16 RGS7

3.13e-03741163EFO_0007886
Diseasecholangiocarcinoma (is_implicated_in)

WDHD1 ABCC2

3.36e-03221162DOID:4947 (is_implicated_in)
Diseasepeak expiratory flow

TSHZ3 ADAM19 KIF1B VSTM4 FIG4 BRD1 PDZRN3

3.60e-034981167EFO_0009718
Diseaseinterleukin 10 measurement

RAPGEF6 JMJD1C H4C7

3.63e-03781163EFO_0004750

Protein segments in the cluster

PeptideGeneStartEntry
HIVWNLLKYRKANRV

ABCA5

651

Q8WWZ7
RRLIWEKNLKYISIH

CTSK

46

P43235
IQRKKQFVERAHSYW

BRD1

466

O95696
RWLRQQLVYAHKKVN

ANKRD30B

1311

Q9BXX2
RLLSATYAVHVWNKK

A4GALT

306

Q9NPC4
SFLSWRRKLLAQKYH

ADAM19

281

Q9H013
WARRHKRETLKATKY

ADAM12

201

O43184
QNIYTWKSRHIVGKR

ASCC1

91

Q8N9N2
SQRRKKALEISHQWY

DMD

1866

P11532
DKYNRAIDSIHQLWK

DOT1L

76

Q8TEK3
HLALSVKRLWQYLVK

DMXL1

2586

Q9Y485
KLQRENYIRQWHSAV

ASPM

2521

Q8IZT6
QKVSYKAKRWIHDVR

ARRDC1

206

Q8N5I2
QKYHDTELQKWREII

GRAMD1B

686

Q3KR37
KYHERNSRLKEEQIW

CCDC83

56

Q8IWF9
RCKWNKHTLTYRIIN

MMP26

96

Q9NRE1
TGNKIRYNSKRRHWK

RPL39P5

31

Q59GN2
KHQTYAVVERWLKEL

RAB25

96

P57735
RYWSKEERKQHLVKA

PDZRN3

971

Q9UPQ7
RNKHSARFKLWYTLD

CYB5R3

226

P00387
HWRKRNIEGKQYLSN

IRF2

251

P14316
AAARVLQAQWKVYKH

IQCE

521

Q6IPM2
KQLQVEYRISKSAWL

P4HA3

381

Q7Z4N8
EKSIYLRLWKRNHCN

AOAH

316

P28039
LDRERLYWKLSQLTH

MUC16

13406

Q8WXI7
SYSHLNWKRRALKEI

OTOP3

516

Q7RTS5
VVHYRKWIKDTIAAN

KLK2

246

P20151
VIWYAVTNTEHAKRK

H4C7

66

Q99525
WRTQQRYLKVLREVK

NFRKB

186

Q6P4R8
RTIQHKYTNWKAFLV

MBTD1

246

Q05BQ5
ALIRIWNYNKSRIHS

KATNIP

1071

O60303
ATHYWSLEKLKQRLD

KIF1B

836

O60333
KWYHRRQAVKELHST

KIAA2026

796

Q5HYC2
DQSWYVNKKLRQRLL

JMJD1C

2426

Q15652
ANVLRETWLIYKHTR

KCNN1

396

Q92952
LRRVYDQLTWKQKSH

CCDC178

396

Q5BJE1
YHVKLLTWEQRQLQK

CCDC190

41

Q86UF4
KIDNDWKRLNTLAHY

PLXNA1

1576

Q9UIW2
EWNEHNAKIIKYIRT

PNN

221

Q9H307
KSRRAERYWQKTLLQ

PLXND1

1296

Q9Y4D7
WSLLSEKQRARYNTK

NSD2

491

O96028
LRNYQKSKVKHEWLS

FBXO48

106

Q5FWF7
IIHDSLQLKKRLRWY

METTL16

231

Q86W50
LYRLWKSRQHSKLLD

NSMF

511

Q6X4W1
YVSALKLLRKRSQVW

MMAA

306

Q8IVH4
WQLLHVYKSRTKRSS

ABCC2

46

Q92887
KVWDVRVNKLLQHYQ

POC1B

211

Q8TC44
HVNTKSLISWNYLRK

MACF1

951

Q9UPN3
LKSLLRLVKHWYQQY

OASL

206

Q15646
KYLLQARTAIIKSSW

OBSCN

5981

Q5VST9
AIKLWAKRHNIYSNI

PAPOLA

226

P51003
LQRWEHLKKVASRYQ

PRIM1

266

P49642
NYLRSKREKFHRTWT

FLT3

701

P36888
KTNILLRYLHQQWDK

DDA1

51

Q9BW61
RQLSEVYIKWQKHSQ

ATM

2196

Q13315
RKNRTVISNWIKYAQ

CRNKL1

236

Q9BZJ0
QKSSKAWYLLRVQVL

ESPL1

891

Q14674
KSQFEAQKIWYEHRL

IDH1

236

O75874
KAWAEVYIIAVQRHK

HEATR5A

1396

Q86XA9
FWHELTQKKLNEYRL

ATG7

26

O95352
HPKAQVRYSVKQEWL

BOC

156

Q9BWV1
IKTNREIIHYIRSKW

GCNT7

211

Q6ZNI0
EIIHYIRSKWSDKNI

GCNT7

216

Q6ZNI0
EYEWIHSQTKRLKFN

CHD2

576

O14647
VHRVKTYRKIAPWTQ

FIG4

551

Q92562
QITRINKTTARLWYK

IL23R

76

Q5VWK5
VTLYVWANLKKNPRH

DNAI7

211

Q6TDU7
HKQEISRLQKRLQWY

CEP162

851

Q5TB80
SKIYWTVHRNLLKAE

C3orf33

191

Q6P1S2
KQKWVEYRSLQLQEH

CYTIP

186

O60759
ERNARIIKWLYSIKQ

FAM110B

346

Q8TC76
IIKWLYSIKQARESQ

FAM110B

351

Q8TC76
YIKFTWKRLRSHSRQ

HRH1

386

P35367
HAWKSRKQSRIYSNA

COLGALT2

591

Q8IYK4
KLIEWENNRLYHKLA

CHIC1

176

Q5VXU3
ATYEIAKRSHNWLKL

LIG1

731

P18858
RQKHLQRYSLTQWVD

S100PBP

376

Q96BU1
HRRQKYLEKIWVITE

DSEL

191

Q8IZU8
KWHLVYRSEVIKNNL

CPNE1

171

Q99829
MNLLYRKTKLEWRQH

NYAP1

1

Q6ZVC0
LKVWRINTKHNIIYV

MRPL3

271

P09001
WSVHTYQTEKQRRKQ

RPH3AL

31

Q9UNE2
LRRKWLNALTKRQEY

KIF13B

1091

Q9NQT8
QIKYWQIQLDRHRLK

RGS7

261

P49802
IRHQSDRYVKIKRNW

RPL32

21

P62910
YWRILNHVEKNTHKV

RAPGEF6

376

Q8TEU7
YTVWHFRRVLLKSLQ

FNTA

131

P49354
KKKNYWLVTVLHDRQ

PRORSD1P

56

A6NEY8
WQRKSIRHCSQRYGK

RHBDF1

101

Q96CC6
RNKSNEDLHKLWYVL

MRPL47

91

Q9HD33
LRNKDVKYALRRTWN

OR8K3

291

Q8NH51
KYEWLVSRIVKNHNE

ARHGAP35

276

Q9NRY4
RYVAVKIHQLNKNWR

TLK2

486

Q86UE8
VYRNRTLQKWHDKTK

AATF

361

Q9NY61
RIYIKIKQWILRAQS

ANKUB1

311

A6NFN9
RRVIDWYQHLQINKK

CNGA4

301

Q8IV77
NTLSWYKKERSTQLR

LINC01553

6

A4QN01
VWDVDSLRRLSKHYK

NLN

536

Q9BYT8
KRSQKELLNYAWQHR

RRP7BP

56

Q9NSQ0
KVTHVEDLNAKWQRY

TNIP2

216

Q8NFZ5
YAAVKIHQLNKSWRD

TLK1

481

Q9UKI8
HPLSRDNKWVVQKYI

TTLL8

381

A6PVC2
RKNVLKEAYSHNLWD

TMEM68

76

Q96MH6
RRKRYALTGQKWQHK

MMP16

116

P51512
WTVLYRRKHKKGQSE

RPL24

51

P83731
VEKSVKLYRRESWSH

WDHD1

206

O75717
THKLESWLRKNYLID

TEX10

376

Q9NXF1
LKRVLLAYARWNKTV

TBC1D30

321

Q9Y2I9
ISHWLANVKYQLRKT

TSHZ2

896

Q9NRE2
ISHWLANVKYQLRRT

TSHZ3

946

Q63HK5
VRCLHTIRNYHKWLK

XKR3

111

Q5GH77
RSLWRHTKQIKLYAT

TAS2R8

206

Q9NYW2
WQSVFNKRKSRVRHY

VSTM4

201

Q8IW00
IQSYEKRLNKIVWRA

VWA3B

926

Q502W6
RISSYVNWIKDHLIK

UBR4

1046

Q5T4S7
VHTRKKDLYDAVWIQ

USP32

1111

Q8NFA0
HQQTEKQRIIWGYKI

UGGT1

1326

Q9NYU2
SKRLIWLYQNLIKHS

UBE3C

111

Q15386
VVHYRKWIKDTIVAN

KLK3

246

P07288
IRKAYSTLNRKWHDK

LRRCC1

896

Q9C099
IQKTVRGWLQKVKYH

MYO5B

771

Q9ULV0
WQRKLYRHQKQSIIR

MYO9B

1016

Q13459
SKIETLRLAKNYIWA

NEUROD6

131

Q96NK8