Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionaldo-keto reductase (NADPH) activity

AKR7L AKR7A3 KCNAB2 KCNAB1

1.05e-0532864GO:0004033
GeneOntologyMolecularFunctionphenanthrene-9,10-epoxide hydrolase activity

AKR7L AKR7A3

5.48e-053862GO:0019119
GeneOntologyMolecularFunctionphenanthrene-epoxide hydrolase activity

AKR7L AKR7A3

5.48e-053862GO:0019118
GeneOntologyMolecularFunctionoxidoreductase activity

ACAD11 AKR7L HSD17B6 CH25H NOXRED1 AKR7A3 KCNAB2 KCNAB1 CYP2U1 ACAD10 ASPDH VCAM1

1.05e-047668612GO:0016491
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor

AKR7L HSD17B6 AKR7A3 KCNAB2 KCNAB1

2.22e-04127865GO:0016616
GeneOntologyMolecularFunctionoxidoreductase activity, acting on CH-OH group of donors

AKR7L HSD17B6 AKR7A3 KCNAB2 KCNAB1

3.26e-04138865GO:0016614
GeneOntologyMolecularFunctionepoxide hydrolase activity

AKR7L AKR7A3

9.83e-0411862GO:0004301
GeneOntologyMolecularFunctionsemaphorin receptor activity

MET PLXNB2

1.18e-0312862GO:0017154
GeneOntologyMolecularFunctionoxidoreductase activity, acting on the CH-CH group of donors, with a flavin as acceptor

ACAD11 ACAD10

1.18e-0312862GO:0052890
GeneOntologyMolecularFunctionacyl-CoA dehydrogenase activity

ACAD11 ACAD10

1.18e-0312862GO:0003995
GeneOntologyMolecularFunctionhydrolase activity, acting on ether bonds

AKR7L AKR7A3

1.39e-0313862GO:0016801
GeneOntologyMolecularFunctionether hydrolase activity

AKR7L AKR7A3

1.39e-0313862GO:0016803
GeneOntologyMolecularFunctionaldose reductase (NADPH) activity

AKR7L AKR7A3

1.61e-0314862GO:0004032
GeneOntologyBiologicalProcesscell-cell adhesion in response to extracellular stimulus

ITGA4 VCAM1

1.76e-052872GO:0140039
MousePhenoabsent epicardium

ITGA4 VCAM1

2.54e-052712MP:0010555
DomainNADP_OxRdtase_dom

AKR7L AKR7A3 KCNAB2 KCNAB1

9.98e-0717874IPR023210
DomainAldo_ket_red

AKR7L AKR7A3 KCNAB2 KCNAB1

9.98e-0717874PF00248
DomainAldo/ket_red/Kv-b

AKR7L AKR7A3 KCNAB2 KCNAB1

9.98e-0717874IPR001395
Domain-

MET AAAS WDR75 MIOS GEMIN5 ARHGEF17 PLXNB2 PHIP FBXW11

2.47e-053338792.130.10.10
DomainWD40/YVTN_repeat-like_dom

MET AAAS WDR75 MIOS GEMIN5 ARHGEF17 PLXNB2 PHIP FBXW11

2.59e-05335879IPR015943
Domain-

AKR7A3 KCNAB2 KCNAB1

5.23e-05168733.20.20.100
DomainK_chnl_volt-dep_bsu_KCNAB-rel

KCNAB2 KCNAB1

6.42e-053872IPR005399
DomainK_chnl_volt-dep_bsu_KCNAB

KCNAB2 KCNAB1

6.42e-053872IPR005983
DomainAPH

ACAD11 ACAD10

1.28e-044872PF01636
DomainAminoglycoside_PTrfase

ACAD11 ACAD10

1.28e-044872IPR002575
DomainNACHT

NOD1 NAIP NLRP4

1.62e-0423873PS50837
DomainNACHT_NTPase

NOD1 NAIP NLRP4

1.62e-0423873IPR007111
DomainAPC_su10/DOC_dom

MYCBP2 CUL9

4.44e-047872IPR004939
DomainDOC

MYCBP2 CUL9

4.44e-047872PS51284
DomainAPC10

MYCBP2 CUL9

4.44e-047872SM01337
DomainANAPC10

MYCBP2 CUL9

4.44e-047872PF03256
DomainWD40_repeat_dom

AAAS WDR75 MIOS GEMIN5 ARHGEF17 PHIP FBXW11

4.73e-04297877IPR017986
DomainResIII

DHX58 IGHMBP2

5.90e-048872PF04851
DomainHelicase/UvrB_N

DHX58 IGHMBP2

5.90e-048872IPR006935
DomainVWFC_1

DGCR2 ZAN SSPOP

6.24e-0436873PS01208
DomainVWC

DGCR2 ZAN SSPOP

7.32e-0438873SM00214
DomainVWFC_2

DGCR2 ZAN SSPOP

7.32e-0438873PS50184
DomainVWF_dom

DGCR2 ZAN SSPOP

9.83e-0442873IPR001007
DomainAcyl-CoA_dh_N

ACAD11 ACAD10

1.15e-0311872PF02771
DomainTIL

ZAN SSPOP

1.37e-0312872PF01826
DomainC8

ZAN SSPOP

1.37e-0312872PF08742
DomainWD40

AAAS WDR75 MIOS GEMIN5 PHIP FBXW11

1.58e-03268876SM00320
DomainAcylCoA_DH/ox_N

ACAD11 ACAD10

1.62e-0313872IPR013786
DomainUnchr_dom_Cys-rich

ZAN SSPOP

1.62e-0313872IPR014853
Domain-

ACAD11 ACAD10

1.62e-03138721.10.540.10
DomainC8

ZAN SSPOP

1.62e-0313872SM00832
DomainAcyl-CoA_dh_1

ACAD11 ACAD10

1.62e-0313872PF00441
DomainARM-like

XPO5 CUL9 MEI1 ARMC2 MED12 HTT

1.64e-03270876IPR011989
DomainWD40_repeat

AAAS WDR75 MIOS GEMIN5 PHIP FBXW11

1.70e-03272876IPR001680
Domain7TM_GPCR_Srsx

LPAR3 MTNR1B TAAR5 CNR1

1.86e-03112874SM01381
DomainTIL_dom

ZAN SSPOP

1.88e-0314872IPR002919
DomainWD_REPEATS_1

AAAS WDR75 MIOS GEMIN5 PHIP FBXW11

1.90e-03278876PS00678
DomainLRRNT

SLITRK2 LINGO3 LINGO2

1.93e-0353873PF01462
DomainQuinoprotein_ADH-like_supfam

WDR75 GEMIN5 PHIP

1.93e-0353873IPR011047
DomainWD_REPEATS_2

AAAS WDR75 MIOS GEMIN5 PHIP FBXW11

1.93e-03279876PS50082
DomainWD_REPEATS_REGION

AAAS WDR75 MIOS GEMIN5 PHIP FBXW11

1.93e-03279876PS50294
DomainAcyl-CoA_Oxase/DH_cen-dom

ACAD11 ACAD10

2.17e-0315872IPR006091
DomainAcyl-CoA_dh_M

ACAD11 ACAD10

2.17e-0315872PF02770
DomainAcylCoA_DH/oxidase_NM_dom

ACAD11 ACAD10

2.17e-0315872IPR009100
DomainVWD

ZAN SSPOP

2.47e-0316872SM00216
DomainVWF_type-D

ZAN SSPOP

2.47e-0316872IPR001846
DomainVWFD

ZAN SSPOP

2.47e-0316872PS51233
DomainAcylCo_DH/oxidase_C

ACAD11 ACAD10

2.47e-0316872IPR009075
DomainVWD

ZAN SSPOP

2.47e-0316872PF00094
DomainVWC_out

ZAN SSPOP

3.48e-0319872SM00215
Domain-

XPO5 CUL9 ARMC2 MED12 HTT

3.80e-032228751.25.10.10
Domain-

SLITRK2 NOD1 NAIP LINGO3 LINGO2 NLRP4

3.87e-033218763.80.10.10
DomainGPCR_Rhodpsn_7TM

LPAR3 GPR6 MAS1L P2RY4 GPR153 MTNR1B TAAR5 GPR88 CNR1

3.96e-03670879IPR017452
Domain7tm_1

LPAR3 GPR6 MAS1L P2RY4 GPR153 MTNR1B TAAR5 GPR88 CNR1

4.24e-03677879PF00001
DomainL_dom-like

SLITRK2 NOD1 NAIP LINGO3 LINGO2 NLRP4

4.30e-03328876IPR032675
DomainG_PROTEIN_RECEP_F1_1

LPAR3 GPR6 MAS1L P2RY4 GPR153 MTNR1B TAAR5 GPR88 CNR1

4.57e-03685879PS00237
Domain-

MYCBP2 CUL9 SSPOP

4.80e-03738732.60.120.260
DomainG_PROTEIN_RECEP_F1_2

LPAR3 GPR6 MAS1L P2RY4 GPR153 MTNR1B TAAR5 GPR88 CNR1

4.84e-03691879PS50262
DomainGPCR_Rhodpsn

LPAR3 GPR6 MAS1L P2RY4 GPR153 MTNR1B TAAR5 GPR88 CNR1

4.88e-03692879IPR000276
Pubmed

Tonic mGluR5/CB1-dependent suppression of inhibition as a pathophysiological hallmark in the striatum of mice carrying a mutant form of huntingtin.

GRM5 CNR1 HTT

1.68e-08390323230231
Pubmed

Huntingtin interacting proteins 14 and 14-like are required for chorioallantoic fusion during early placental development.

ITGA4 VCAM1 HTT

1.67e-07590325478910
Pubmed

Heterotypic interactions among NACHT domains: implications for regulation of innate immune responses.

NOD1 NAIP NLRP4

1.39e-06990315107016
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

DGCR2 ARAP3 MDN1 PCNX3 MYCBP2 TMEM94 GEMIN5 CUL9 PLXNB2 FAAP100 FBXO46 MED12 HTT

5.35e-061105901335748872
Pubmed

Genetic analysis of alpha 4 integrin functions in the development of mouse skeletal muscle.

ITGA4 VCAM1

6.62e-0629028909554
Pubmed

Myocardial Blood Flow Control by Oxygen Sensing Vascular Kvβ Proteins.

KCNAB2 KCNAB1

6.62e-06290233499656
Pubmed

Genetic modifiers of the Kv beta2-null phenotype in mice.

KCNAB2 KCNAB1

6.62e-06290215720404
Pubmed

Localization of two potassium channel beta subunit genes, KCNA1B and KCNA2B.

KCNAB2 KCNAB1

6.62e-0629028838324
Pubmed

Airway recruitment of leukocytes in mice is dependent on alpha4-integrins and vascular cell adhesion molecule-1.

ITGA4 VCAM1

6.62e-0629029124372
Pubmed

Orchestrated activation of mGluR5 and CB1 promotes neuroprotection.

GRM5 CNR1

6.62e-06290227543109
Pubmed

Cannabinoid-1 (CB1) receptors regulate colonic propulsion by acting at motor neurons within the ascending motor pathways in mouse colon.

GRM5 CNR1

6.62e-06290219033531
Pubmed

Metabotropic glutamate receptor-mediated cell signaling pathways are altered in a mouse model of Huntington's disease.

GRM5 HTT

6.62e-06290220053912
Pubmed

Activated integrin VLA-4 localizes to the lamellipodia and mediates T cell migration on VCAM-1.

ITGA4 VCAM1

6.62e-06290219542447
Pubmed

Shaker K+ channel beta subunits belong to an NAD(P)H-dependent oxidoreductase superfamily.

KCNAB2 KCNAB1

6.62e-0629028001150
Pubmed

Human immunodeficiency virus (HIV) type 1 Vpu induces the expression of CD40 in endothelial cells and regulates HIV-induced adhesion of B-lymphoma cells.

CD40 VCAM1

6.62e-06290215078922
Pubmed

IgA ASC accumulation to the lactating mammary gland is dependent on VCAM-1 and alpha4 integrins.

ITGA4 VCAM1

6.62e-06290220171738
Pubmed

Activation of type 5 metabotropic glutamate receptors and diacylglycerol lipase-α initiates 2-arachidonoylglycerol formation and endocannabinoid-mediated analgesia.

GRM5 CNR1

6.62e-06290222787031
Pubmed

Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease.

GRM5 HTT

6.62e-06290224282028
Pubmed

Modulation of mTOR and CREB pathways following mGluR5 blockade contribute to improved Huntington's pathology in zQ175 mice.

GRM5 HTT

6.62e-06290230961637
Pubmed

Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington's Disease and Other Neurodegenerative Disorders.

GPR88 CNR1 HTT

1.33e-051890327405468
Pubmed

[Purification of recombinant AKR7A5 protein and measurement of substrate specificity of AKR7A5 towards naphthoquinone and its derivatives].

AKR7L AKR7A3

1.98e-05390222863590
Pubmed

Critical role of the alpha 4 integrin/VCAM-1 pathway in cerebral leukocyte trafficking in lupus-prone MRL/fas(lpr) mice.

ITGA4 VCAM1

1.98e-05390212496439
Pubmed

Developmental expression of voltage-gated potassium channel beta subunits.

KCNAB2 KCNAB1

1.98e-05390210536234
Pubmed

Structural requirements for adhesion of soluble recombinant murine vascular cell adhesion molecule-1 to alpha 4 beta 1.

ITGA4 VCAM1

1.98e-0539027515889
Pubmed

Hierarchy of molecular-pathway usage in bone marrow homing and its shift by cytokines.

ITGA4 VCAM1

1.98e-05390216141352
Pubmed

FAK inhibition reduces metastasis of α4 integrin-expressing melanoma to lymph nodes by targeting lymphatic VCAM-1 expression.

ITGA4 VCAM1

1.98e-05390230660359
Pubmed

Alpha4 and beta2 integrins have nonredundant roles for asthma development, but for optimal allergen sensitization only alpha4 is critical.

ITGA4 VCAM1

1.98e-05390217379071
Pubmed

Characterisation of a novel mouse liver aldo-keto reductase AKR7A5.

AKR7L AKR7A3

1.98e-05390212123834
Pubmed

VCAM1-α4β1 integrin interaction mediates interstitial tissue reconstruction in 3-D re-aggregate culture of dissociated prepubertal mouse testicular cells.

ITGA4 VCAM1

1.98e-05390234526555
Pubmed

Essential role of VLA-4/VCAM-1 pathway in the establishment of CD8+ T-cell-mediated Trypanosoma cruzi-elicited meningoencephalitis.

ITGA4 VCAM1

1.98e-05390214512161
Pubmed

Aldo-keto reductase 7A5 (AKR7A5) attenuates oxidative stress and reactive aldehyde toxicity in V79-4 cells.

AKR7L AKR7A3

1.98e-05390224590062
Pubmed

Ligation of lymphocyte function-associated antigen-1 on monocytes decreases very late antigen-4-mediated adhesion through a reactive oxygen species-dependent pathway.

ITGA4 VCAM1

1.98e-05390215308572
Pubmed

Anti-alpha4 integrin antibody suppresses the development of multiple myeloma and associated osteoclastic osteolysis.

ITGA4 VCAM1

1.98e-05390215138161
Pubmed

Localization of mGluR5, GABAB, GABAA, and cannabinoid receptors on the vago-vagal reflex pathway responsible for transient lower esophageal sphincter relaxation in humans: an immunohistochemical study.

GRM5 CNR1

1.98e-05390222256945
Pubmed

Bortezomib is a rapid mobilizer of hematopoietic stem cells in mice via modulation of the VCAM-1/VLA-4 axis.

ITGA4 VCAM1

1.98e-05390225342668
Pubmed

The macrophage contribution to stress erythropoiesis: when less is enough.

ITGA4 VCAM1

1.98e-05390227543439
Pubmed

Targeted disruption of the murine VCAM1 gene: essential role of VCAM-1 in chorioallantoic fusion and placentation.

ITGA4 VCAM1

1.98e-0539027530222
Pubmed

The heat-stable antigen can alter very late antigen 4-mediated adhesion.

ITGA4 VCAM1

1.98e-0539028145052
Pubmed

Enhanced stem cell migration mediated by VCAM-1/VLA-4 interaction improves cardiac function in virus-induced dilated cardiomyopathy.

ITGA4 VCAM1

1.98e-05390224065117
Pubmed

The role of vascular cell adhesion molecule 1/ very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium.

ITGA4 VCAM1

1.98e-05390217530710
Pubmed

Novel homodimeric and heterodimeric rat gamma-hydroxybutyrate synthases that associate with the Golgi apparatus define a distinct subclass of aldo-keto reductase 7 family proteins.

AKR7L AKR7A3

1.98e-05390212071861
Pubmed

Mouse aldo-keto reductase AKR7A5 protects V79 cells against 4-hydroxynonenal-induced apoptosis.

AKR7L AKR7A3

1.98e-05390216919859
Pubmed

Defective development of the embryonic and extraembryonic circulatory systems in vascular cell adhesion molecule (VCAM-1) deficient mice.

ITGA4 VCAM1

1.98e-0539027539357
Pubmed

Cell adhesion events mediated by alpha 4 integrins are essential in placental and cardiac development.

ITGA4 VCAM1

1.98e-0539027539359
Pubmed

AKR7A5 knockout promote acute liver injury by inducing inflammatory response, oxidative stress and apoptosis in mice.

AKR7L AKR7A3

1.98e-05390239365156
Pubmed

VCAM1 acts in parallel with CD69 and is required for the initiation of oligodendrocyte myelination.

ITGA4 VCAM1

1.98e-05390227876794
Pubmed

High affinity interaction of integrin alpha4beta1 (VLA-4) and vascular cell adhesion molecule 1 (VCAM-1) enhances migration of human melanoma cells across activated endothelial cell layers.

ITGA4 VCAM1

1.98e-05390217352405
Pubmed

Alternative splicing of the human Shaker K+ channel beta 1 gene and functional expression of the beta 2 gene product.

KCNAB2 KCNAB1

1.98e-0539027649300
Pubmed

Increased Levels of VCAM-1 in Sera and VLA-4 Expression on Neutrophils in Dermatomyositis with Interstitial Lung Disease.

ITGA4 VCAM1

1.98e-05390233724131
Pubmed

LRRN6A/LERN1 (leucine-rich repeat neuronal protein 1), a novel gene with enriched expression in limbic system and neocortex.

LINGO3 LINGO2

1.98e-05390214686891
Pubmed

Vascular cell adhesion molecule-1 and the integrin VLA-4 mediate adhesion of human B cell precursors to cultured bone marrow adherent cells.

ITGA4 VCAM1

1.98e-0539021715889
Pubmed

Extracellular-signal regulated kinase 1-dependent metabotropic glutamate receptor 5-induced long-term depression in the bed nucleus of the stria terminalis is disrupted by cocaine administration.

GRM5 CNR1

1.98e-05390216554472
Pubmed

Selective interaction of voltage-gated K+ channel beta-subunits with alpha-subunits.

KCNAB2 KCNAB1

1.98e-0539028636142
Pubmed

Expression of Fas, FasL, caspase-8 and other factors of the extrinsic apoptotic pathway during the onset of interdigital tissue elimination.

NOD1 CD40 NAIP

3.26e-052490327709293
Pubmed

Tumor suppressor p53 regulates heat shock factor 1 protein degradation in Huntington's disease.

GPR88 HTT

3.96e-05490236867535
Pubmed

Identification and characterization of new long chain acyl-CoA dehydrogenases.

ACAD11 ACAD10

3.96e-05490221237683
Pubmed

Aflatoxin B1 aldehyde reductase (AFAR) genes cluster at 1p35-1p36.1 in a region frequently altered in human tumour cells.

AKR7L AKR7A3

3.96e-05490212879023
Pubmed

A new K+ channel beta subunit to specifically enhance Kv2.2 (CDRK) expression.

KCNAB2 KCNAB1

3.96e-0549028824288
Pubmed

Expression of the Lingo/LERN gene family during mouse embryogenesis.

LINGO3 LINGO2

3.96e-05490218297755
Pubmed

Talin 1 and paxillin facilitate distinct steps in rapid VLA-4-mediated adhesion strengthening to vascular cell adhesion molecule 1.

ITGA4 VCAM1

3.96e-05490217597073
Pubmed

Localization of alpha 4m integrin at sites of mesenchyme condensation during embryonic mouse development.

ITGA4 VCAM1

3.96e-0549028522070
Pubmed

Crosstalk between CXCR4/stromal derived factor-1 and VLA-4/VCAM-1 pathways regulates neutrophil retention in the bone marrow.

ITGA4 VCAM1

3.96e-05490219109194
Pubmed

VCAM-1 and VLA-4 modulate dendritic cell IL-12p40 production in experimental visceral leishmaniasis.

ITGA4 VCAM1

3.96e-05490218802456
Pubmed

Alpha-4 integrins and VCAM-1, but not MAdCAM-1, are essential for recruitment of mast cell progenitors to the inflamed lung.

ITGA4 VCAM1

3.96e-05490216670268
Pubmed

Actin polymerization stabilizes α4β1 integrin anchors that mediate monocyte adhesion.

ITGA4 VCAM1

3.96e-05490222472442
Pubmed

Human mast cell progenitors use alpha4-integrin, VCAM-1, and PSGL-1 E-selectin for adhesive interactions with human vascular endothelium under flow conditions.

ITGA4 VCAM1

3.96e-05490211929779
Pubmed

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity.

ITGA4 VCAM1

3.96e-05490228414311
Pubmed

Dual functions of [alpha]4[beta]1 integrin in epicardial development: initial migration and long-term attachment.

ITGA4 VCAM1

3.96e-05490212021259
Pubmed

Receptor Tyrosine Kinase MET Interactome and Neurodevelopmental Disorder Partners at the Developing Synapse.

MET GRM5

3.96e-05490227086544
Pubmed

Reciprocal leukemia-stroma VCAM-1/VLA-4-dependent activation of NF-κB mediates chemoresistance.

ITGA4 VCAM1

3.96e-05490224599548
Pubmed

Similar but nonidentical amino acid residues on vascular cell adhesion molecule-1 are involved in the interaction with alpha 4 beta 1 and alpha 4 beta 7 under different activity states.

ITGA4 VCAM1

3.96e-0549027594538
Pubmed

Sustained alterations in biodistribution of stem/progenitor cells in Tie2Cre+ alpha4(f/f) mice are hematopoietic cell autonomous.

ITGA4 VCAM1

3.96e-05490216931623
Pubmed

The alpha 4 beta 1 fibronectin ligands CS-1, Hep II, and RGD induce different intracellular events in B lymphoid cells. Comparison with the effects of the endothelial ligand VCAM-1.

ITGA4 VCAM1

3.96e-0549029117345
Pubmed

Increased expression of cell adhesion molecules in inflammatory myopathies: diagnostic utility and pathogenetic insights.

ITGA4 VCAM1

3.96e-05490219353432
Pubmed

Accessory Kvbeta1 subunits differentially modulate the functional expression of voltage-gated K+ channels in mouse ventricular myocytes.

KCNAB2 KCNAB1

3.96e-05490215662035
Pubmed

Tie2 Signaling Enhances Mast Cell Progenitor Adhesion to Vascular Cell Adhesion Molecule-1 (VCAM-1) through α4β1 Integrin.

ITGA4 VCAM1

3.96e-05490226659448
Pubmed

Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.

MDN1 WDR75 MYCBP2 XPO5 STRBP GEMIN5 CUL9 PHIP MED12

5.01e-0565390922586326
Pubmed

Tetraspanins CD81 and CD82 facilitate α4β1-mediated adhesion of human erythroblasts to vascular cell adhesion molecule-1.

ITGA4 VCAM1

6.59e-05590223704882
Pubmed

beta-amyloid-induced migration of monocytes across human brain endothelial cells involves RAGE and PECAM-1.

ITGA4 VCAM1

6.59e-05590211078691
Pubmed

mGluR5 regulates REST/NRSF signaling through N-cadherin/β-catenin complex in Huntington's disease.

GRM5 HTT

6.59e-05590232859226
Pubmed

Expression of cell adhesion molecules in murine placentas and a placental cell line.

ITGA4 VCAM1

6.59e-0559029916011
Pubmed

Integrin alpha4beta1 (VLA-4) expression and activity in retinal and peripheral neurons.

ITGA4 VCAM1

6.59e-05590212837626
Pubmed

Abl-interactor-1 (Abi1) has a role in cardiovascular and placental development and is a binding partner of the alpha4 integrin.

ITGA4 VCAM1

6.59e-05590221173240
Pubmed

Combinatorial and distinct roles of α₅ and α₄ integrins in stress erythropoiesis in mice.

ITGA4 VCAM1

6.59e-05590220956802
Pubmed

Interplay between scatter factor receptors and B plexins controls invasive growth.

MET PLXNB2

6.59e-05590215184888
Pubmed

Both ICAM-1- and VCAM-1-integrin interactions are important in mediating monocyte adhesion to human saphenous vein.

ITGA4 VCAM1

6.59e-05590212097820
Pubmed

The cannabinoid-1 receptor is abundantly expressed in striatal striosomes and striosome-dendron bouquets of the substantia nigra.

GPR88 CNR1

9.87e-05690229466446
Pubmed

Differential stimulation of PKC phosphorylation of potassium channels by ZIP1 and ZIP2.

KCNAB2 KCNAB1

9.87e-05690210477520
Pubmed

Defective blood vessel development and pericyte/pvSMC distribution in alpha 4 integrin-deficient mouse embryos.

ITGA4 VCAM1

9.87e-05690216529735
Pubmed

SGT1 is essential for Nod1 activation.

NOD1 NLRP4

9.87e-05690217420470
Pubmed

Specialized patterns of vascular differentiation antigens in the pregnant mouse uterus and the placenta.

ITGA4 VCAM1

9.87e-05690210569981
Pubmed

Threonine phosphorylation sites in the beta 2 and beta 7 leukocyte integrin polypeptides.

ITGA4 VCAM1

9.87e-05690212682249
Pubmed

A crucial function of SGT1 and HSP90 in inflammasome activity links mammalian and plant innate immune responses.

NOD1 NLRP4

9.87e-05690217435760
Pubmed

Regulation of cellular adhesion molecule expression in murine oocytes, peri-implantation and post-implantation embryos.

ITGA4 VCAM1

9.87e-05690212528895
Pubmed

Mrj encodes a DnaJ-related co-chaperone that is essential for murine placental development.

ITGA4 VCAM1

9.87e-05690210021343
Pubmed

Genetic predictors of depressive symptoms in cardiac patients.

VCAM1 CNR1

9.87e-05690218618671
Pubmed

Epicardial-myocardial signaling directing coronary vasculogenesis.

ITGA4 VCAM1 SMAD6

1.22e-043790320299672
Pubmed

Expanding roles for alpha 4 integrin and its ligands in development.

ITGA4 VCAM1

1.38e-0479027526952
Pubmed

CD4+CD3- cells induce Peyer's patch development: role of alpha4beta1 integrin activation by CXCR5.

ITGA4 VCAM1

1.38e-04790212354388
Pubmed

Expression of astrocyte-related receptors in cortical dysplasia with intractable epilepsy.

P2RY4 GRM5

1.38e-04790225003238
Cytoband1p36.13

RNF186 AKR7L AKR7A3

1.87e-04569031p36.13
CytobandXq13

P2RY4 MED12

2.92e-0413902Xq13
GeneFamilyAldo-keto reductases

AKR7A3 KCNAB2 KCNAB1

1.87e-0515643399
GeneFamilyNLR family

NOD1 NAIP NLRP4

9.20e-0525643666
GeneFamilyG protein-coupled receptors, Class A orphans

GPR6 MAS1L GPR153 GPR88

1.67e-0478644262
GeneFamilyAcyl-CoA dehydrogenase family

ACAD11 ACAD10

6.65e-0411642974
GeneFamilyPotassium voltage-gated channel regulatory subunits|DASH family

KCNAB2 KCNAB1

1.26e-0315642858
GeneFamilyWD repeat domain containing

AAAS WDR75 GEMIN5 PHIP FBXW11

2.34e-03262645362
CoexpressionGSE25088_IL4_VS_IL4_AND_ROSIGLITAZONE_STIM_MACROPHAGE_DAY10_DN

CFH MET LPAR3 MYCBP2 GPR88 PLXNB2 HTT

5.93e-06200907M7983
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

CFH NOD1 SLC43A1 SLC9A7 ARMC2 MED12

1.41e-06173906090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

CFH NOD1 SLC43A1 SLC9A7 ARMC2 MED12

1.46e-06174906a79ebb01a5849c314e02594a9c95009dbb03cb8c
ToppCellwk_20-22-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

TMEM88 CFH MET ARAP3 MEDAG SMAD6

1.56e-0617690652af8f717dbd3b59eeb868b8b7b256a8f3e57d7a
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SLITRK2 HSD17B6 GAS1 MEDAG VCAM1

2.74e-06194906c578cf7c6b4d6f31f87dde8845de5b3891f16822
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SLITRK2 HSD17B6 GAS1 MEDAG VCAM1

2.74e-06194906f4286ae7bb8350c42d50727ee8688b80129714f6
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

CFH SLITRK2 HSD17B6 GAS1 MEDAG VCAM1

2.74e-0619490687461bd6d7f702c0a0f5e0c8ace3049125a51f9a
ToppCelldistal-1-mesenchymal-Mesothelial|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

CFH SLITRK2 HSD17B6 GAS1 MEDAG VCAM1

3.17e-061999068dd5b411d2f1626830b77a1616cc3fb67dc59338
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MDN1 TMEM94 NOXRED1 MIOS ITGA4

7.25e-0613290546c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCellLPS-IL1RA+antiTNF-Unknown|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MDN1 TMEM94 NOXRED1 MIOS ITGA4

7.25e-06132905a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma-3|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

RNF186 AKR7L AKR7A3 NR0B2 SMAD6

1.18e-05146905e55b4acecf4e363b5afa287c747c2e58c4597f3a
ToppCellTCGA-Head_and_Esophagus-Primary_Tumor-Esophageal_Carcinoma-Adenocarcinoma|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9

RNF186 AKR7L AKR7A3 NR0B2 SMAD6

1.30e-0514990592a8931a51db619fb5f0638d319c02e7838f6559
ToppCellprimary_visual_cortex-Neuronal-glutamatergic_neuron-L2/3_IT-L2/3_IT_VISp_Adamts2|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype

ADCY10 MET LINGO2 ITGA4 GPR88

1.63e-051569052cd007b423c2395c5ce331902e7f27c805755eb3
ToppCellwk_15-18-Endothelial-Blood_vessel_endothelial-OMD+_endo|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CFH MET MEDAG CNR1 SMAD6

3.15e-051799058c9ed247e1c4d655b81ce2f24a9936a7cade718a
ToppCelldroplet-Heart-4Chambers-18m-Mesenchymal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 GAS1 MEDAG ARHGEF17

3.41e-05182905f4b74c2756989812abe4e7055ec8918f69d56025
ToppCellControl-Neu_4|World / 5 Neutrophil clusters in COVID-19 patients

OMA1 CIAO3 KCNAB2 GEMIN5 HTT

3.59e-05184905ce7f044956613118ee2e9fb6af2455c3166cb414
ToppCelltumor_Lung-Fibroblasts-Mesothelial_cells|tumor_Lung / Location, Cell class and cell subclass

CFH SLITRK2 HSD17B6 GAS1 MEDAG

3.59e-05184905b0a251030d127858e68cf164be158f209a4d720f
ToppCellproximal-3-Hematologic-Myeloid_Dendritic_Type_1|3 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GPR153 SLC9A7 ITGA4 FBXO46 PIK3R5

3.78e-05186905c920dffd24f051b54d8b48f801fffc928d99e135
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1-3|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GPR153 SLC9A7 ITGA4 FBXO46 PIK3R5

3.78e-05186905d740aca5dc4240851ba7bc5988c0970d785ad0c2
ToppCellproximal-Hematologic-Myeloid_Dendritic_Type_1|proximal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

GPR153 SLC9A7 ITGA4 FBXO46 PIK3R5

3.78e-051869054ca7f6c043874a0c536f75af5ca24c7c66725e54
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 SLC43A1 GAS1 MEDAG

3.88e-051879054e553721fa5598cb211f44e3226280b7e6885484
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 SLC43A1 GAS1 MEDAG

3.88e-05187905d36e7fc6125e7a4310499365022d38f34b757a73
ToppCelldroplet-Pancreas-Exocrine-18m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 SLC43A1 GAS1 MEDAG

3.88e-05187905827eae63fabf6892a82ce7779b5f395958d3d628
ToppCelldroplet-Lung-1m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l17|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH SLC43A1 GAS1 MEDAG KCNAB1

3.88e-05187905ed7ab4cf4629d96dad5c74d536fc428d0a8d4eb9
ToppCelldroplet-Lung-3m-Mesenchymal-fibroblast-alveolar_fibroblast-alveolar_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH GAS1 CH25H GPR88 VCAM1

3.98e-05188905b382d18fb09fb2869f3c151efa71540a7f5ed229
ToppCellCOPD-Epithelial-Mesothelial|COPD / Disease state, Lineage and Cell class

CFH MET GAS1 MEDAG VCAM1

4.08e-0518990579bb2593ad5d17f94b17972884241f03a0f43770
ToppCell3'-Parenchyma_lung-Mesenchymal-Fibro-meso-mesothelial_cell-Mesothelium-Mesothelium_L.2.6.0.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLITRK2 HSD17B6 GAS1 MEDAG VCAM1

4.19e-05190905f39ce1678fc375eb2a3af781ddb772b0f12c5744
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-Cd34+|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 GAS1 MEDAG VCAM1

4.29e-051919056cab0334f76c973880bd8d1638856f2f6e4a249a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 GAS1 MEDAG VCAM1

4.29e-05191905850c6fff6dc795431ef534fdaa41e4ad50f7367a
ToppCelldroplet-Fat-Gat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH GPR153 GAS1 MEDAG VCAM1

4.29e-051919058b2b00202d3c98bccbae1b4a23713892fad0ff23
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH GPR153 GAS1 MEDAG VCAM1

4.29e-051919058a73d2df079566fca4cbb5cdb85721c2e87134c8
ToppCelldroplet-Lung-21m-Mesenchymal|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH GPR153 GAS1 MEDAG VCAM1

4.29e-0519190510a9db1caa0fdb51ace8537f42b2c66f7c97e0f5
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast-adventitial_fibroblast_l1|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH GPR153 GAS1 MEDAG VCAM1

4.40e-051929057b48df661f61ce494bf6f0b9a74b0422e29c24bf
ToppCellfacs-Lung-3m-Mesenchymal-fibroblast-adventitial_fibroblast|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH GPR153 GAS1 MEDAG VCAM1

4.40e-0519290532acd89617934016cd135d2cc797e8e79ae1b37f
ToppCelldroplet-Lung-21m-Mesenchymal-fibroblast-adventitial_fibroblast|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CFH GPR153 GAS1 MEDAG VCAM1

4.62e-05194905ca1f24070424b44b7a442e4fca761ebfbe24b063
ToppCellBronchus_Control_(B.)-Stromal-TX-Mesothelial-2|Bronchus_Control_(B.) / Sample group, Lineage and Cell type

HSD17B6 GAS1 MEDAG VCAM1 SMAD6

5.22e-0519990560a653100aff31f7f96796ff2ec634798bfb4b0d
ToppCellBiopsy_IPF-Mesenchymal-Mesothelial_cells|Biopsy_IPF / Sample group, Lineage and Cell type

SLITRK2 HSD17B6 GAS1 MEDAG VCAM1

5.34e-05200905553386523fd8f8f36617a0d81032224b7ddce442
ToppCellSepsis-ICU-SEP-Myeloid-cDC2|ICU-SEP / Disease, condition lineage and cell class

DHX58 CGRRF1 SLC9A7 SUV39H2 BIK

5.34e-0520090509d5c3a3d2b42b15c769dc2bc14b6c0d5cc38f91
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)-|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM94 CIAO3 ACSF3 BIK

9.65e-0511890408bdf7bc3c9dcbc0f690658fe14e6cc4b9581698
ToppCell356C-Epithelial_cells-Epithelial-H_(AT1)|Epithelial_cells / Donor, Lineage, Cell class and subclass (all cells)

TMEM94 CIAO3 ACSF3 BIK

9.65e-051189043b077ad5c68c01b3fcc93f203cb130bb90705af9
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1|Cerebellum / BrainAtlas - Mouse McCarroll V32

LPAR3 LINGO2 ACAD10 ASPDH

1.13e-04123904e0eb95f1da12687230b47f0a7367b6138bc7ff1a
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1|Cerebellum / BrainAtlas - Mouse McCarroll V32

LPAR3 LINGO2 ACAD10 ASPDH

1.13e-04123904356e2b1b47fdfc2bb2fcd45e44b452fe811f0fd8
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)-|Cerebellum / BrainAtlas - Mouse McCarroll V32

LPAR3 LINGO2 ACAD10 ASPDH

1.13e-04123904b06a38d1081b4485b519853d8c9a2cddfb1e9e75
ToppCellCerebellum-Macroglia-POLYDENDROCYTE-P1-P1_1-Polydendrocyte.Tnr.Tnr_(Tnr)|Cerebellum / BrainAtlas - Mouse McCarroll V32

LPAR3 LINGO2 ACAD10 ASPDH

1.13e-04123904f60c1dd89da0e204f73772fe0c319eeca82e7e8a
ToppCellCerebellum-Macroglia-POLYDENDROCYTE|Cerebellum / BrainAtlas - Mouse McCarroll V32

LPAR3 LINGO2 ACAD10 ASPDH

1.13e-0412390415f951b4eb2f39888e51e1af18c329953d253f7f
ToppCellStriatum-Macroglia-OLIGODENDROCYTE-O1-Trf|Striatum / BrainAtlas - Mouse McCarroll V32

SPOCD1 NLRP4 OCSTAMP

1.42e-04509031f1fee2a62d0665ac6ef8ece456c51e3cec3a6b6
ToppCellStriatum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)|Striatum / BrainAtlas - Mouse McCarroll V32

SPOCD1 NLRP4 OCSTAMP

1.42e-0450903301eaec701ee1f7ce825dfb905c37c7107e3dc88
ToppCellStriatum-Macroglia-OLIGODENDROCYTE-O1-Trf-Oligodendrocyte.Trf.Il33_(Il33)-|Striatum / BrainAtlas - Mouse McCarroll V32

SPOCD1 NLRP4 OCSTAMP

1.42e-04509035c06f52adbb2bbcf156f82e930948b10331ed730
ToppCellStriatum-Macroglia-OLIGODENDROCYTE-O1|Striatum / BrainAtlas - Mouse McCarroll V32

SPOCD1 NLRP4 OCSTAMP

1.42e-0450903041339abc4feded9a58b797204e04052e338c009
ToppCellTracheal-NucSeq-Immune_Myeloid-Macrophage_other-Macro_interstitial|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GPR153 KCNAB2 ITGA4 PIK3R5

2.13e-04145904778655fffd73df101e656154a41b478a1b695116
ToppCellfacs-Brain_Non-Myeloid-Hippocampus-24m-Macroglial-oligodendrocyte|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ADCY10 CFAP92 FAM53B SSPOP

2.43e-04150904afd651c654e715414eff64cf3a37378d057a56a2
ToppCellPBMC-Control-Lymphocyte-B-B_cell-B_naive-B_naive-9|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

STRBP CD40 SLC9A7 FAAP100

2.49e-041519042314c004434aed9b7fa1ad01c61c43e5ed4a18ce
ToppCellLPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

MDN1 CGRRF1 TMEM94 NOXRED1

2.68e-0415490416fdafb5c64d2db321554f87129a962d113f1668
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 ACAD10 ARMC2 SMAD6

2.75e-04155904cd2f3ad4f131588325a667b6724e530d821fbe30
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

TMEM94 KCNAB1 ITGA4 HTT

2.75e-041559045687416773809b8c478567bc54310af102b3029a
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-MPP_Fraction_B|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 ACAD10 ARMC2 SMAD6

2.75e-041559049b26ade19488511c72b64335011d2dcd81e8f167
ToppCellfacs-Marrow-Granulocytes-3m-Hematologic-hematopoietic_stem_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 ACAD10 ARMC2 SMAD6

2.75e-041559044246709e27703b94529369abbed5763e4002e79d
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Kif5b_(Kif5b)-|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

M1AP P2RY4 SSPOP

2.82e-046390350ea93ea08d8e7a1a2508e8a2c569f6f5dc91961
ToppCellFrontal_cortex-Macroglia-OLIGODENDROCYTE-O2-Tnr-Oligodendrocyte.Tnf.Kif5b_(Kif5b)|Frontal_cortex / BrainAtlas - Mouse McCarroll V32

M1AP P2RY4 SSPOP

2.82e-0463903c30197502348f07ded57ad4e50862e61e2fba51e
ToppCelltumor_Lung-B_lymphocytes-GC_B_cells_in_the_LZ|tumor_Lung / Location, Cell class and cell subclass

P2RY4 CD40 NLRP4 BIK

2.82e-04156904b5851474ba14dd2b4867415828b52dd98ecdd6d3
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial-endothelial_cell|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 PRSS45P NR0B2 SMAD6

2.89e-04157904b6ecf1d8c6a465ff31cbc181e00ea88b76b38e19
ToppCellfacs-Limb_Muscle-Muscle_Diaphragm-18m-Endothelial|Limb_Muscle / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TMEM88 PRSS45P NR0B2 SMAD6

2.89e-0415790401ad5cbaf91010e79216e1fb37b7b890618c5f28
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte-nonclassical_monocyte_l4|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

M1AP ITGA4 PLXNB2 PIK3R5

2.96e-04158904121d63b8e2e37107467b170e5b2c798a7dbf6325
ToppCellfacs-Liver-Non-hepatocytes-3m-Myeloid-myeloid_leukocyte|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

KCNAB2 LINGO3 LINGO2 ITGA4

3.10e-04160904237430af14830b38e58da8a4224036e5c6b71c5b
ToppCellfacs-Lung-18m-Hematologic-myeloid-non-classical_monocyte|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

M1AP ITGA4 PLXNB2 PIK3R5

3.10e-04160904bc4a93dc5f37829799c37877e751ff3bc122e4ab
ToppCellwk_20-22-Hematologic_Lymphocytic-T_&_ILC-T_entry|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CFAP92 CYP2U1 ITGA4 SPOCD1

3.25e-04162904a27750117e7f16a0bd07cc5f58a56becb39e800b
ToppCellE18.5-Immune-Immune_Lymphocytic_T/NK-Lymphocytic_B-B-B_mature|E18.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

M1AP XPO5 NOXRED1 GEMIN5

3.25e-0416290459f6a9005c4f22f084c25ea36f3cacce5144a9ae
ToppCell356C-Lymphocytic-NK_cells-NK_cell_E|356C / Donor, Lineage, Cell class and subclass (all cells)

NOD1 SLC43A1 ARMC2 MED12

3.41e-04164904d5bb57c321f2973836efc8990449494cc1fb87c7
ToppCellfacs-Aorta-Heart-3m-Mesenchymal-fibrocyte|Aorta / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFAP92 SLC9A7 ITGA4 SSPOP

3.49e-041659048a52f2dbcbd2bc1662b5e3fac381463fdcc3bf14
ToppCellControl-Epithelial-Mesothelial|World / Disease state, Lineage and Cell class

CFH SLITRK2 MEDAG VCAM1

3.57e-0416690432ebaefa6c074b28193fff764ee7c2c0e9357e20
ToppCellControl-Epithelial-Mesothelial|Control / Disease state, Lineage and Cell class

CFH SLITRK2 MEDAG VCAM1

3.57e-041669041ed3788257e14f097862b999f020bfe2a57de52b
ToppCellCOVID-19-kidney-PEC|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH MET GRM5 VCAM1

3.73e-04168904a086c306be430adf0632ba53e98cd8014d2de330
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)-Cbln1|Hippocampus / BrainAtlas - Mouse McCarroll V32

ADCY10 MEI1 GPR88

3.85e-04709038d6bdf2e773e894a0db39fdff1fafc2474e03fcf
ToppCellwk_15-18-Epithelial-Proximal_epithelial-Pulmonary_NE_precursor|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

GPR6 RNF186 NR0B2 BIK

3.90e-0417090498d13dbd76a826e47d55553f9d11f71c043b573e
ToppCellTCGA-Liver-Primary_Tumor-Hepatocellular_Carcinoma-Hepatocellular_Carcinoma-8|TCGA-Liver / Sample_Type by Project: Shred V9

TMEM88 CFH HSD17B6 AKR7A3

3.99e-04171904c4a919fe3d56ae6df2fcab6686abacc10befc053
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM88 CFH CH25H VCAM1

4.08e-04172904fc092a0631555d79e00ef9890cbd806e15bca2d4
ToppCellPND28-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

TMEM88 CFH CH25H VCAM1

4.08e-04172904745725bd10c82017d678463b8fef0d2dcf09a8fd
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

TMEM88 XPO5 SLC49A4 FBXO46

4.08e-04172904da959c1abadafd79b7a0088a25eb8ef8efa3a0c2
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)-|367C / Donor, Lineage, Cell class and subclass (all cells)

SLITRK2 HSD17B6 MEDAG VCAM1

4.17e-04173904e05cddf5bf63cf419343ff229453327519765be8
ToppCell367C-Fibroblasts-Fibroblast-J_(Lipofibroblast)|367C / Donor, Lineage, Cell class and subclass (all cells)

SLITRK2 HSD17B6 MEDAG VCAM1

4.17e-0417390474ad5ed33821b8816c9c8e67c50ee4496ba18e2f
ToppCellfacs-Brain_Myeloid-Hippocampus-3m-Myeloid-macrophage|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

LPAR3 CD40 KCNAB2 ITGA4

4.17e-04173904c63a615998d13b1725b5767f4ad2ec7e2b61db68
ToppCell3'-Child09-12-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CFH GAS1 MEDAG KCNAB1

4.17e-0417390411e95a60b5f6f07f27154a23203bac431e7528c6
ToppCellfacs-Heart-RA-24m-Endothelial-endothelial_cell_of_endocardium|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH VCAM1 SMAD6 BIK

4.26e-0417490442dfb6f42b72e40e203b3ef341117bccf3553d54
ToppCellfacs-Heart-RA-24m-Endothelial-endocardial_cell|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH VCAM1 SMAD6 BIK

4.26e-04174904f04edf2ca6788875c9918611e416fb739924382e
ToppCelldroplet-Fat-Bat-18m-Mesenchymal-nan|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR75 GPR153 MEDAG KCNAB1

4.35e-04175904b4f01e7782cdd107d0817ef601891fd3a382bc35
ToppCelldroplet-Fat-Bat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR75 GPR153 MEDAG KCNAB1

4.35e-04175904ef6f811d8e1839f405c3b41090ddf79be57a099f
ToppCelldroplet-Fat-Bat-18m-Mesenchymal|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation

WDR75 GPR153 MEDAG KCNAB1

4.35e-041759047f7598d46d10bff1cbea42f950bdde1aaa16e9a4
ToppCellfacs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GPR153 NOXRED1 GRM5 PIK3R5

4.35e-04175904f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCellCOVID-19-B_cells-Activated_B_cells|COVID-19 / group, cell type (main and fine annotations)

STRBP SLC9A7 ITGA4 CNR1

4.54e-04177904653bb62a3744d4024ab3186ee01d410ed62832a6
ToppCellnucseq-Mesenchymal-Fibroblastic-Fibroblastic_1-Mesothelial|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

CFH SLITRK2 MEDAG VCAM1

4.54e-041779040912a291cff32a4ff8a2d7680ed1a1cd867fb90f
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM88 SLITRK2 CH25H VCAM1

4.64e-04178904ebfae386a518ea33911ba3ff40464c94d18ef695
ToppCellCOVID-19-kidney-Epi_(Mes)|COVID-19 / Disease (COVID-19 only), tissue and cell type

CFH MET GRM5 VCAM1

4.64e-04178904544379f5a6145429762258d426b876bb36c112f5
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial-vein_endothelial_cell-vein_endothelial_cell|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM88 SLITRK2 CH25H VCAM1

4.64e-04178904ccd37575b60102f5e647c01546e8ff8fec638bd7
ToppCellfacs-Lung-18m-Endothelial-venous_endothelial|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

TMEM88 SLITRK2 CH25H VCAM1

4.64e-0417890487b04753650e45f12299c8456fb980d6c0d5961c
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SLC43A1 GPR88 VCAM1

4.74e-041799046f51a4580c06fc55cc764052c9b26f7c55660282
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SLC43A1 GPR88 VCAM1

4.74e-04179904f14440f6ce9b4fcdd4bcb2488b949f9a0e17bc23
ToppCellEndothelial|World / shred by cell class for turbinate

TMEM88 MEDAG VCAM1 CNR1

4.74e-04179904052b2681974be00efb8503fa4e2c85d91d5ebd06
ToppCellILEUM-non-inflamed-(8)_Fibroblast-(8)_Activated_fibroblasts|(8)_Fibroblast / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

GAS1 MEDAG RHBDD3 SMAD6

4.74e-041799045787ffba96918db80256ced076a455a84ba01384
ToppCellfacs-Pancreas-Endocrine-24m-Mesenchymal-pancreatic_stellate_cell|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CFH SLC43A1 GPR88 VCAM1

4.74e-04179904a6ce1fa338d4905bd6afef00763ac83e916a0b37
ToppCellIPF-Epithelial-Mesothelial|IPF / Disease state, Lineage and Cell class

CFH GAS1 MEDAG VCAM1

4.84e-041809041fa54bf4dba72866b2295639d991af639341bc08
ToppCellP28-Mesenchymal-mesenchymal_fibroblast-mesenchymal_alveolar_niche_cell|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase

CFH GAS1 MEDAG GPR88

4.84e-041809049adebde5f4ca6dcb90e9113622862e14298465ac
Diseasevascular cell adhesion protein 1 measurement

CFH ITGA4 VCAM1

8.59e-077873EFO_0020846
Diseasehomeodomain-interacting protein kinase 3 measurement

CFH SLC9A7

8.59e-062872EFO_0020457
Diseasemonocyte:lymphocyte ratio

LINC01565 ITGA4

8.54e-055872EFO_0007956
Diseasetumor necrosis factor receptor superfamily member 19L measurement

CFH ARHGEF17

2.38e-048872EFO_0008309
DiseaseMultiple Sclerosis

CD40 VCAM1 CNR1

3.21e-0445873C0026769
DiseaseMultiple Sclerosis, Acute Fulminating

CD40 VCAM1 CNR1

3.21e-0445873C0751324
DiseaseHuntington Disease, Late Onset

CNR1 HTT

5.56e-0412872C0393574
DiseaseAkinetic-Rigid Variant of Huntington Disease

CNR1 HTT

5.56e-0412872C0751207
DiseaseJuvenile Huntington Disease

CNR1 HTT

5.56e-0412872C0751208
Diseasemultiple myeloma (is_implicated_in)

MET XPO5 CD40

7.14e-0459873DOID:9538 (is_implicated_in)
DiseaseGrand Mal Status Epilepticus

CD40 GRM5 CNR1

1.03e-0367873C0311335
DiseaseStatus Epilepticus, Subclinical

CD40 GRM5 CNR1

1.03e-0367873C0751522
DiseaseSimple Partial Status Epilepticus

CD40 GRM5 CNR1

1.03e-0367873C0751524
DiseaseNon-Convulsive Status Epilepticus

CD40 GRM5 CNR1

1.03e-0367873C0751523
DiseasePetit mal status

CD40 GRM5 CNR1

1.03e-0367873C0270823
DiseaseComplex Partial Status Epilepticus

CD40 GRM5 CNR1

1.03e-0367873C0393734
DiseaseStatus Epilepticus

CD40 GRM5 CNR1

1.08e-0368873C0038220
DiseaseHuntington Disease

CNR1 HTT

1.14e-0317872C0020179
Diseaseperiodontitis (biomarker_via_orthology)

MET VCAM1

1.74e-0321872DOID:824 (biomarker_via_orthology)
DiseaseAttention Deficit Disorder

GRM5 CNR1

1.91e-0322872C0041671
DiseaseMinimal Brain Dysfunction

GRM5 CNR1

1.91e-0322872C1321905
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM5 CNR1

2.09e-0323872C0393672
DiseaseEpilepsy, Lateral Temporal

GRM5 CNR1

2.09e-0323872C0393682
Diseaseclinical and behavioural ideal cardiovascular health

MTNR1B LINGO2

2.09e-0323872EFO_0007654
DiseaseUncinate Epilepsy

GRM5 CNR1

2.09e-0323872C0014558
DiseaseEpilepsy, Temporal Lobe

GRM5 CNR1

2.09e-0323872C0014556
DiseaseEtat Marbre

CNR1 HTT

2.09e-0323872C0266487
Diseaseneutrophil-to-lymphocyte ratio

LINC01565 CFAP92 ITGA4 VCAM1

2.22e-03185874EFO_0008447
DiseaseAttention deficit hyperactivity disorder

GRM5 CNR1

2.27e-0324872C1263846
Diseasebirth weight, parental genotype effect measurement

ARAP3 MTNR1B KCNAB1 ARMC2

2.54e-03192874EFO_0004344, EFO_0005939

Protein segments in the cluster

PeptideGeneStartEntry
LWASGCCPLLNRFQL

NAIP

486

Q13075
VACQSCILIWTLDPT

AAAS

211

Q9NRG9
SNPSLVNNCWLCISL

nan

56

Q9N2K0
SNPSLANNCWLCISL

nan

56

Q9N2J8
QWCQLPEPCSASLLL

ARAP3

1191

Q8WWN8
AEICTLCKSNGWILP

AKR7L

151

Q8NHP1
AEICTLCKSNGWILP

AKR7A3

151

O95154
CLRDLGPTDWQLACL

ARMC2

766

Q8NEN0
GPTDWQLACLVCKTL

ARMC2

771

Q8NEN0
DELRQGWLLQCPQCA

LINC01565

86

O15544
GWLLQCPQCARTLLC

LINC01565

91

O15544
WITGILDPRCQLCVF

ACAD10

826

Q6JQN1
VNALLCPLWVGATCV

ACSF3

251

Q4G176
THCLPCSQQLLLVLW

CFAP92

391

Q9ULG3
IQCVDGEWTTLPVCI

CFH

671

P08603
DVILSPNCWQLCDRS

ADCY10

186

Q96PN6
NPGSWVSCEQVLLAL

BIK

126

Q13323
WLEPLLQGNITSCFC

ACAD11

491

Q709F0
LWCGCQNRVLVLSPD

ARHGEF17

1831

Q96PE2
LEQLSWLLQCCPSVG

MDN1

4301

Q9NU22
LPNITLGCEIRDSCW

GRM5

86

P41594
SWLLCCALSALNPLL

GPR88

321

Q9GZN0
IQRALWLLLCGCFQS

GPR6

336

P46095
LPSWADICTNLCEAL

M1AP

31

Q8TC57
LGCTLPQLAVAWCLR

KCNAB1

351

Q14722
VTAFWQSLLACCQLP

ASPDH

261

A6ND91
ACLIFLNCTLNWPIE

SLC43A1

206

O75387
AICWAPLNCIGLAVA

MTNR1B

261

P49286
CPLQIDQPSTSIWEC

FAM53B

56

Q14153
QDWNSPLVTLCFGLC

PCNX3

1571

Q9H6A9
LEENLPCISCVSNRW

PLXNB2

621

O15031
CRLGLHDNNWVLPCN

FBXO46

576

Q6PJ61
EVGCQPLQTLWLCRI

LENG9

471

Q96B70
CSVPRSLWLGCANLV

FBXW11

16

Q9UKB1
CVLWCSVAQALLLPV

GPR153

281

Q6NV75
NPNLCSLCSVPLFCW

NOD1

381

Q9Y239
AVPTLGWNCLCNISA

LPAR3

161

Q9UBY5
GNPLACDCRLLWIVQ

LINGO3

351

P0C6S8
SINNNPLACDCRLLW

LINGO2

351

Q7L985
LQTILLCCPSALVWH

MED12

366

Q93074
LICWQALLQCQGEPE

GAS1

46

P54826
SEQLFSICQIPLLCW

NLRP4

331

Q96MN2
PSLAAVQWLQCCLES

NR0B2

141

Q15466
VPLCCATLQWLLAEN

FAAP100

726

Q0VG06
WTCDCELALLPLAQL

MEDAG

26

Q5VYS4
CTLPQLAIAWCLRNE

KCNAB2

301

Q13303
NVVCTLIWGLPFCIN

MAS1L

191

P35410
VWSSCNCLTLLVEEP

MEI1

341

Q5TIA1
CLAVWLVVAGCLVPN

P2RY4

156

P51582
ICLNSQVLLVNICPW

CYP2U1

261

Q7Z449
CCCLALQLPGLWSVV

HTT

2281

P42858
NNAGILTPITLCEWL

HSD17B6

111

O14756
NWCLPGSCLLSLLLI

SLC49A4

446

Q96SL1
LQLCANLDTWCIMSP

DHX58

186

Q96C10
PLLGWNCEKLQSVCS

CNR1

251

P21554
ACRSGTIQCIPLPWQ

DGCR2

36

P98153
CVENGWPSVCIDLTL

ITGA4

486

P13612
NLTWCTNPQGCDRIL

CUL9

2156

Q8IWT3
VCQNGTVNWVLLPCR

CGRRF1

276

Q99675
VLCSSGQLFLQPLWD

CH25H

11

O95992
WADVIFLCCLPSQLP

NOXRED1

136

Q6NXP6
LCVQDNTWSITCPLC

RNF186

71

Q9NXI6
CLSGTWTQQICLPAI

MET

551

P08581
QWLEEMPCVGSCQLL

TAAR5

181

O14804
ISCTCGNVPETWIIL

VCAM1

621

P19320
ECPCVLTAWLLQELG

SSPOP

3751

A2VEC9
TRQQPCPGLLEACSW

SSPOP

4301

A2VEC9
ITSCPCWLEILLNNP

SMAD6

481

O43541
PGKLQELCCTLSWVS

FAM178B

486

Q8IXR5
IQLEENPWNCTCDLL

SLITRK2

211

Q9H156
WPLELICEKSIGTCN

STRBP

241

Q96SI9
TPALQWACLCDLLNC

MYCBP2

1556

O75592
LWSCRDLSCNLGPVP

OCSTAMP

501

Q9BR26
ICPRDSLALLCQWIQ

OMA1

361

Q96E52
QALPLLASACPGWIC

CIAO3

181

Q9H6Q4
LQEGVLCRTLAGCWP

RHBDD3

196

Q9Y3P4
PCASACLLFLCWLLQ

PRSS45P

241

Q7RTY3
SPCLCLLWEDTLTPN

TRIM77

36

I1YAP6
LGQNDACLSLCWLPR

MIOS

181

Q9NXC5
VWCLRTCAPLAVLQG

PHIP

251

Q8WWQ0
GLCLNCWSLQELVSR

PIK3R5

36

Q8WYR1
TVLCCVDKQGILSWP

TMEM94

411

Q12767
ENGILCCWNLLSCAL

WDR75

561

Q8IWA0
ECAQALEASCWIPLL

IGHMBP2

376

P38935
CIPSNIVWDLLASIC

SPOCD1

906

Q6ZMY3
AWCVPCLVSLDTLQE

SUV39H2

11

Q9H5I1
IAWCPLPGEDCLSIN

GEMIN5

201

Q8TEQ6
TLSCQRTTSQLCWPL

XPO5

1041

Q9HAV4
PLDCWACAVLVTAQN

TMEM88

21

Q6PEY1
QSISCVCLPELGALW

nan

11

Q6ZVQ6
AWCGLLARCLTSPQV

SLC9A7

626

Q96T83
LWPACQESVTALCFL

ZGLP1

46

P0C6A0
VLWCLTGVQCPRFTL

ZPBP2

11

Q6X784
LQCVLWGCLLTAVHP

CD40

6

P25942
LCCAALSLLWAGPVN

TRBV6-5

6

A0A0K0K1A5
STCKPNQICWALDGL

ZAN

1906

Q9Y493