Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	hydrolase activity, hydrolyzing O-glycosyl compounds	HEXA MGAM OVGP1 CHI3L1 GAA	7.40e-05	103	84	5	GO:0004553
GeneOntologyMolecularFunction	alpha-1,4-glucosidase activity	MGAM GAA	1.73e-04	5	84	2	GO:0004558
GeneOntologyMolecularFunction	scavenger receptor binding	FPR2 FPR3	1.73e-04	5	84	2	GO:0005124
GeneOntologyMolecularFunction	N-formyl peptide receptor activity	FPR2 FPR3	1.73e-04	5	84	2	GO:0004982
GeneOntologyMolecularFunction	chitinase activity	OVGP1 CHI3L1	2.59e-04	6	84	2	GO:0004568
GeneOntologyMolecularFunction	hydrolase activity, acting on glycosyl bonds	HEXA MGAM OVGP1 CHI3L1 GAA	3.55e-04	144	84	5	GO:0016798
GeneOntologyMolecularFunction	ceramide 1-phosphate binding	PLEKHA8P1 PLEKHA8	3.62e-04	7	84	2	GO:1902387
GeneOntologyMolecularFunction	ceramide 1-phosphate transfer activity	PLEKHA8P1 PLEKHA8	3.62e-04	7	84	2	GO:1902388
GeneOntologyMolecularFunction	alpha-glucosidase activity	MGAM GAA	3.62e-04	7	84	2	GO:0090599
GeneOntologyMolecularFunction	chitin binding	OVGP1 CHI3L1	4.82e-04	8	84	2	GO:0008061
GeneOntologyMolecularFunction	ceramide transfer activity	PLEKHA8P1 PLEKHA8	4.82e-04	8	84	2	GO:0120017
GeneOntologyMolecularFunction	thyroid hormone transmembrane transporter activity	SLC16A2 SLCO4A1	6.18e-04	9	84	2	GO:0015349
GeneOntologyMolecularFunction	sphingolipid transfer activity	PLEKHA8P1 PLEKHA8	6.18e-04	9	84	2	GO:0120016
GeneOntologyMolecularFunction	complement receptor activity	FPR2 FPR3	1.54e-03	14	84	2	GO:0004875
GeneOntologyMolecularFunction	G protein-coupled photoreceptor activity	OPN4 RGR	1.77e-03	15	84	2	GO:0008020
GeneOntologyMolecularFunction	RAGE receptor binding	FPR2 FPR3	1.77e-03	15	84	2	GO:0050786
GeneOntologyMolecularFunction	glucosidase activity	MGAM GAA	1.77e-03	15	84	2	GO:0015926
GeneOntologyMolecularFunction	photoreceptor activity	OPN4 RGR	2.28e-03	17	84	2	GO:0009881
GeneOntologyMolecularFunction	G protein-coupled peptide receptor activity	FPR2 FPR3 MRGPRX2 SORCS1	2.40e-03	133	84	4	GO:0008528
GeneOntologyCellularComponent	secretory granule membrane	MGAM FPR2 TMEM63B DMBT1 ITGAL ITGAV GAA ITPR1	5.33e-05	329	84	8	GO:0030667
GeneOntologyCellularComponent	stereocilium tip	LHFPL5 STRC STRCP1	9.12e-05	22	84	3	GO:0032426
MousePheno	abnormal sensory neuron physiology	FPR2 FPR3 TMEM63B STRC STRCP1	2.74e-05	72	69	5	MP:0010055
MousePheno	abnormal somatic nervous system physiology	FPR2 FPR3 TMEM63B STRC STRCP1	5.45e-05	83	69	5	MP:0005423
Domain	Glycoside_hydrolase_SF	HEXA MGAM OVGP1 CHI3L1 GAA	2.92e-06	53	79	5	IPR017853
Domain	Formyl_pep_2/3_rcpt	FPR2 FPR3	1.77e-05	2	79	2	IPR027347
Domain	Glycolipid_transfer_prot_dom	PLEKHA8P1 PLEKHA8	1.05e-04	4	79	2	IPR014830
Domain	Glyco_hydro_31_CS	MGAM GAA	1.05e-04	4	79	2	IPR030459
Domain	NtCtMGAM_N	MGAM GAA	1.05e-04	4	79	2	PF16863
Domain	Gal_mutarotase_N	MGAM GAA	1.05e-04	4	79	2	IPR031727
Domain	GLTP	PLEKHA8P1 PLEKHA8	1.05e-04	4	79	2	PF08718
Domain	Chitinase_insertion	OVGP1 CHI3L1	1.75e-04	5	79	2	IPR029070
Domain	GLYCOSYL_HYDROL_F31_2	MGAM GAA	1.75e-04	5	79	2	PS00707
Domain	-	OVGP1 CHI3L1	1.75e-04	5	79	2	3.10.50.10
Domain	Glyco_hydro_18_chit_AS	OVGP1 CHI3L1	2.62e-04	6	79	2	IPR001579
Domain	Glyco_hydro_31_AS	MGAM GAA	2.62e-04	6	79	2	IPR030458
Domain	Glyco_hydro18_cat	OVGP1 CHI3L1	3.66e-04	7	79	2	IPR001223
Domain	Glyco_hydro_31	MGAM GAA	3.66e-04	7	79	2	IPR000322
Domain	Glyco_hydro_18	OVGP1 CHI3L1	3.66e-04	7	79	2	PF00704
Domain	Chitinase_II	OVGP1 CHI3L1	3.66e-04	7	79	2	IPR011583
Domain	Glyco_18	OVGP1 CHI3L1	3.66e-04	7	79	2	SM00636
Domain	Glyco_hydro_31	MGAM GAA	3.66e-04	7	79	2	PF01055
Domain	CHITINASE_18	OVGP1 CHI3L1	3.66e-04	7	79	2	PS01095
Domain	GLYCOSYL_HYDROL_F31_1	MGAM GAA	3.66e-04	7	79	2	PS00129
Domain	-	HEXA OVGP1 CHI3L1	4.32e-04	35	79	3	3.20.20.80
Domain	Trefoil	MGAM GAA	4.87e-04	8	79	2	PF00088
Domain	P_TREFOIL_1	MGAM GAA	4.87e-04	8	79	2	PS00025
Domain	Retinal_BS	OPN4 RGR	4.87e-04	8	79	2	IPR027430
Domain	P_trefoil_CS	MGAM GAA	4.87e-04	8	79	2	IPR017957
Domain	Glyco_hydro_catalytic_dom	HEXA OVGP1 CHI3L1	5.52e-04	38	79	3	IPR013781
Domain	P_TREFOIL_2	MGAM GAA	6.24e-04	9	79	2	PS51448
Domain	PD	MGAM GAA	6.24e-04	9	79	2	SM00018
Domain	Sialidases	RELN SORCS1	6.24e-04	9	79	2	IPR011040
Domain	OPSIN	OPN4 RGR	7.78e-04	10	79	2	PS00238
Domain	Formyl_rcpt-rel	FPR2 FPR3	7.78e-04	10	79	2	IPR000826
Domain	-	MGAM GAA	9.48e-04	11	79	2	4.10.110.10
Domain	Opsin	OPN4 RGR	9.48e-04	11	79	2	IPR001760
Domain	Integrin_alpha	ITGAL ITGAV	9.48e-04	11	79	2	PF00357
Domain	P_trefoil_dom	MGAM GAA	1.13e-03	12	79	2	IPR000519
Domain	SEA	IMPG1 MUC16	1.56e-03	14	79	2	SM00200
Domain	OAR	PITX1 ARX	1.79e-03	15	79	2	PF03826
Domain	-	IMPG1 MUC16	1.79e-03	15	79	2	3.30.70.960
Domain	OAR	PITX1 ARX	2.04e-03	16	79	2	PS50803
Domain	Integrin_alpha_C_CS	ITGAL ITGAV	2.04e-03	16	79	2	IPR018184
Domain	OAR_dom	PITX1 ARX	2.04e-03	16	79	2	IPR003654
Domain	Gal_mutarotase_SF_dom	MGAM GAA	2.31e-03	17	79	2	IPR011013
Domain	Integrin_alpha-2	ITGAL ITGAV	2.59e-03	18	79	2	IPR013649
Domain	Integrin_alpha2	ITGAL ITGAV	2.59e-03	18	79	2	PF08441
Domain	Integrin_alpha	ITGAL ITGAV	2.59e-03	18	79	2	IPR000413
Domain	INTEGRIN_ALPHA	ITGAL ITGAV	2.59e-03	18	79	2	PS00242
Domain	Int_alpha_beta-p	ITGAL ITGAV	2.88e-03	19	79	2	IPR013519
Domain	Int_alpha	ITGAL ITGAV	2.88e-03	19	79	2	SM00191
Domain	FG_GAP	ITGAL ITGAV	3.86e-03	22	79	2	PS51470
Domain	SEA	IMPG1 MUC16	3.86e-03	22	79	2	PF01390
Domain	SEA	IMPG1 MUC16	4.22e-03	23	79	2	PS50024
Domain	SEA_dom	IMPG1 MUC16	4.22e-03	23	79	2	IPR000082
Domain	FG-GAP	ITGAL ITGAV	4.59e-03	24	79	2	PF01839
Domain	FG-GAP	ITGAL ITGAV	4.59e-03	24	79	2	IPR013517
Domain	Integrin_dom	ITGAL ITGAV	4.98e-03	25	79	2	IPR032695
Domain	7tm_1	OPN4 OR4C11 OR6C4 FPR2 FPR3 MRGPRX2 RGR OR4C5	7.76e-03	677	79	8	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OPN4 OR4C11 OR6C4 FPR2 FPR3 MRGPRX2 RGR OR4C5	8.31e-03	685	79	8	PS00237
Pubmed	Resolvin D1 protects the liver from ischemia/reperfusion injury by enhancing M2 macrophage polarization and efferocytosis.	FPR2 FPR3	5.90e-06	2	85	2	27317426
Pubmed	Glucose-dependent transcriptional regulation by an evolutionarily conserved glucose-sensing module.	MLXIPL MLXIP	5.90e-06	2	85	2	16644671
Pubmed	N-formyl peptide receptor 3 (FPR3) departs from the homologous FPR2/ALX receptor with regard to the major processes governing chemoattractant receptor regulation, expression at the cell surface, and phosphorylation.	FPR2 FPR3	5.90e-06	2	85	2	21543323
Pubmed	Serum YKL-40 levels in patients with ovarian cancer and women with BRCA1 gene mutation--comparison to CA 125 antigen.	MUC16 CHI3L1	5.90e-06	2	85	2	20099501
Pubmed	Formyl peptide receptors: a promiscuous subfamily of G protein-coupled receptors controlling immune responses.	FPR2 FPR3	5.90e-06	2	85	2	17084101
Pubmed	Contrasting Patterns in the Evolution of Vertebrate MLX Interacting Protein (MLXIP) and MLX Interacting Protein-Like (MLXIPL) Genes.	MLXIPL MLXIP	5.90e-06	2	85	2	26910886
Pubmed	Strain-specific Loss of Formyl Peptide Receptor 3 in the Murine Vomeronasal and Immune Systems.	FPR2 FPR3	5.90e-06	2	85	2	26957543
Pubmed	Mutations in a new gene encoding a protein of the hair bundle cause non-syndromic deafness at the DFNB16 locus.	STRC STRCP1	5.90e-06	2	85	2	11687802
Pubmed	Aspirin-triggered 15-epi-lipoxin A4 (LXA4) and LXA4 stable analogues are potent inhibitors of acute inflammation: evidence for anti-inflammatory receptors.	FPR2 FPR3	5.90e-06	2	85	2	9151906
Pubmed	Multi-pronged inhibition of airway hyper-responsiveness and inflammation by lipoxin A(4).	FPR2 FPR3	5.90e-06	2	85	2	12172542
Pubmed	Lipoxin A4 inhibits the production of proinflammatory cytokines induced by β-amyloid in vitro and in vivo.	FPR2 FPR3	5.90e-06	2	85	2	21501589
Pubmed	Nonredundant protective properties of FPR2/ALX in polymicrobial murine sepsis.	FPR2 FPR3	5.90e-06	2	85	2	25512512
Pubmed	Preoperative serum levels of YKL 40 and CA125 as a prognostic indicators in patients with endometrial cancer.	MUC16 CHI3L1	5.90e-06	2	85	2	28624692
Pubmed	MondoA Is an Essential Glucose-Responsive Transcription Factor in Human Pancreatic β-Cells.	MLXIPL MLXIP	5.90e-06	2	85	2	29282201
Pubmed	A vasculo-protective circuit centered on lipoxin A4 and aspirin-triggered 15-epi-lipoxin A4 operative in murine microcirculation.	FPR2 FPR3	5.90e-06	2	85	2	23733341
Pubmed	Dual-vector gene therapy restores cochlear amplification and auditory sensitivity in a mouse model of DFNB16 hearing loss.	STRC STRCP1	5.90e-06	2	85	2	34910522
Pubmed	Differential expression of members of the N-formylpeptide receptor gene cluster in human phagocytes.	FPR2 FPR3	5.90e-06	2	85	2	8198572
Pubmed	Genetic evidence for ubiquitin-specific proteases USP24 and USP40 as candidate genes for late-onset Parkinson disease.	USP40 USP24	5.90e-06	2	85	2	16917932
Pubmed	Genetic factors contributing to autism spectrum disorder in Williams-Beuren syndrome.	MLXIPL UBR5	5.90e-06	2	85	2	31413120
Pubmed	Reversal of β-Amyloid-Induced Microglial Toxicity In Vitro by Activation of Fpr2/3.	FPR2 FPR3	5.90e-06	2	85	2	32617132
Pubmed	N-Formylated humanin activates both formyl peptide receptor-like 1 and 2.	FPR2 FPR3	5.90e-06	2	85	2	15465011
Pubmed	A novel rat lipoxin A4 receptor that is conserved in structure and function.	FPR2 FPR3	5.90e-06	2	85	2	12746227
Pubmed	Association analysis of single-nucleotide polymorphisms of USP24 and USP40 with Parkinson's disease in the Han Chinese population.	USP40 USP24	5.90e-06	2	85	2	22923019
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	HEXA PNPLA6 ZNF827 KIF26A MYO10 PITX1 USP40 SLCO4A1 MLLT6 DEPDC5 MLXIP SBNO2	1.55e-05	1105	85	12	35748872
Pubmed	Neuroanatomical distribution of ARX in brain and its localisation in GABAergic neurons.	RELN ARX	1.77e-05	3	85	2	14992814
Pubmed	Defective formyl peptide receptor 2/3 and annexin A1 expressions associated with M2a polarization of blood immune cells in patients with chronic obstructive pulmonary disease.	FPR2 FPR3	1.77e-05	3	85	2	29544524
Pubmed	Cochlear outer hair cell horizontal top connectors mediate mature stereocilia bundle mechanics.	STRC STRCP1	1.77e-05	3	85	2	30801007
Pubmed	The pro-inflammatory peptide LL-37 promotes ovarian tumor progression through recruitment of multipotent mesenchymal stromal cells.	FPR2 FPR3	1.77e-05	3	85	2	19234121
Pubmed	Identification, cloning, and functional characterization of a murine lipoxin A4 receptor homologue gene.	FPR2 FPR3	1.77e-05	3	85	2	12218158
Pubmed	Characterization of two new members of the formyl peptide receptor gene family from 129S6 mice.	FPR2 FPR3	1.77e-05	3	85	2	12459252
Pubmed	ALOX5AP Overexpression in Adipose Tissue Leads to LXA4 Production and Protection Against Diet-Induced Obesity and Insulin Resistance.	FPR2 FPR3	1.77e-05	3	85	2	27207555
Pubmed	Formyl peptide receptor 2 regulates monocyte recruitment to promote intestinal mucosal wound repair.	FPR2 FPR3	1.77e-05	3	85	2	31585047
Pubmed	FoxO4 mediates macrophage M2 polarization by promoting LXA4R expression in an ovalbumin-induced allergic asthma model in mice.	FPR2 FPR3	1.77e-05	3	85	2	37422776
Pubmed	Reelin is required for class-specific retinogeniculate targeting.	RELN OPN4	1.77e-05	3	85	2	21228166
Pubmed	Functional expression of formyl peptide receptor family in human NK cells.	FPR2 FPR3	1.77e-05	3	85	2	19843937
Pubmed	Helicobacter pylori HP(2-20) induces eosinophil activation and accumulation in superficial gastric mucosa and stimulates VEGF-alpha and TGF-beta release by interacting with formyl-peptide receptors.	FPR2 FPR3	1.77e-05	3	85	2	24067461
Pubmed	Formyl peptide receptor 1 up-regulation and formyl peptide receptor 2/3 down-regulation of blood immune cells along with defective lipoxin A4/resolvin D1 production in obstructive sleep apnea patients.	FPR2 FPR3	1.77e-05	3	85	2	31116781
Pubmed	TXNIP induced by MondoA, rather than ChREBP, suppresses cervical cancer cell proliferation, migration and invasion.	MLXIPL MLXIP	1.77e-05	3	85	2	31782782
Pubmed	Formyl peptide receptors and the regulation of ACTH secretion: targets for annexin A1, lipoxins, and bacterial peptides.	FPR2 FPR3	1.77e-05	3	85	2	17218541
Pubmed	International Union of Basic and Clinical Pharmacology. LXXIII. Nomenclature for the formyl peptide receptor (FPR) family.	FPR2 FPR3	1.77e-05	3	85	2	19498085
Pubmed	Ubiquitin specific proteases USP24 and USP40 and ubiquitin thiolesterase UCHL1 polymorphisms have synergic effect on the risk of Parkinson's disease among Taiwanese.	USP40 USP24	1.77e-05	3	85	2	20302855
Pubmed	Mouse cathelin-related antimicrobial peptide chemoattracts leukocytes using formyl peptide receptor-like 1/mouse formyl peptide receptor-like 2 as the receptor and acts as an immune adjuvant.	FPR2 FPR3	1.77e-05	3	85	2	15879124
Pubmed	Formyl peptide receptors from immune and vomeronasal system exhibit distinct agonist properties.	FPR2 FPR3	1.77e-05	3	85	2	22859307
Pubmed	Phagocyte activation by Trp-Lys-Tyr-Met-Val-Met, acting through FPRL1/LXA4R, is not affected by lipoxin A4.	FPR2 FPR3	1.77e-05	3	85	2	12410796
Pubmed	Formyl peptide receptor 2 is an emerging modulator of inflammation in the liver.	FPR2 FPR3	1.77e-05	3	85	2	36750693
Pubmed	Formyl peptide receptor-like 2 is expressed and functional in plasmacytoid dendritic cells, tissue-specific macrophage subpopulations, and eosinophils.	FPR2 FPR3	1.77e-05	3	85	2	19342677
Pubmed	Deletion of Annexin A1 in Mice Upregulates the Expression of Its Receptor, Fpr2/3, and Reactivity to the AnxA1 Mimetic Peptide in Platelets.	FPR2 FPR3	1.77e-05	3	85	2	36834844
Pubmed	Formyl peptide receptors are candidate chemosensory receptors in the vomeronasal organ.	FPR2 FPR3	1.77e-05	3	85	2	19497865
Pubmed	Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production.	FPR2 FPR3	1.77e-05	3	85	2	20435922
Pubmed	Mapping of genes for the human C5a receptor (C5AR), human FMLP receptor (FPR), and two FMLP receptor homologue orphan receptors (FPRH1, FPRH2) to chromosome 19.	FPR2 FPR3	3.53e-05	4	85	2	1612600
Pubmed	Stereocilin-deficient mice reveal the origin of cochlear waveform distortions.	STRC STRCP1	3.53e-05	4	85	2	18849963
Pubmed	The cross-talk between the urokinase receptor and fMLP receptors regulates the activity of the CXCR4 chemokine receptor.	FPR3 ITGAV	3.53e-05	4	85	2	20972812
Pubmed	A mouse homologue of Strawberry Notch is transcriptionally regulated by Reelin signal.	RELN SBNO2	3.53e-05	4	85	2	17045962
Pubmed	Developmental expression and intracellular location of P400 protein characteristic of Purkinje cells in the mouse cerebellum.	RELN ITPR1	3.53e-05	4	85	2	2707487
Pubmed	The N-formylpeptide receptor (FPR) and a second G(i)-coupled receptor mediate fMet-Leu-Phe-stimulated activation of NADPH oxidase in murine neutrophils.	FPR2 FPR3	3.53e-05	4	85	2	12470609
Pubmed	Leukocyte antiadhesive actions of annexin 1: ALXR- and FPR-related anti-inflammatory mechanisms.	FPR2 FPR3	3.53e-05	4	85	2	12560218
Pubmed	An annexin 1 N-terminal peptide activates leukocytes by triggering different members of the formyl peptide receptor family.	FPR2 FPR3	3.53e-05	4	85	2	15187149
Pubmed	Lipoxin A4 attenuates hyperoxia‑induced lung epithelial cell injury via the upregulation of heme oxygenase‑1 and inhibition of proinflammatory cytokines.	FPR2 FPR3	3.53e-05	4	85	2	31746387
Pubmed	Splicing variations in the ligand-binding domain of ApoER2 results in functional differences in the binding properties to Reelin.	RELN ITPR1	5.87e-05	5	85	2	19167437
Pubmed	MondoA-Mlx transcriptional activity is limited by mTOR-MondoA interaction.	MLXIPL MLXIP	5.87e-05	5	85	2	25332233
Pubmed	Proteomic and biochemical studies of calcium- and phosphorylation-dependent calmodulin complexes in Mammalian cells.	UBR5 ITPR1	5.87e-05	5	85	2	17696464
Pubmed	Convergence of FPR-rs3-expressing neurons in the mouse accessory olfactory bulb.	FPR2 FPR3	5.87e-05	5	85	2	23664818
Pubmed	Expression of opsin genes early in ocular development of humans and mice.	OPN4 RGR	5.87e-05	5	85	2	12573668
Pubmed	An unusually powerful mode of low-frequency sound interference due to defective hair bundles of the auditory outer hair cells.	STRC STRCP1	5.87e-05	5	85	2	24920589
Pubmed	Angiopoietin-like 3 induces podocyte F-actin rearrangement through integrin α(V)β₃/FAK/PI3K pathway-mediated Rac1 activation.	PIK3R1 ITGAV	8.80e-05	6	85	2	24294595
Pubmed	Integrins take partners: cross-talk between integrins and other membrane receptors.	ITGAL ITGAV	8.80e-05	6	85	2	9789327
Pubmed	Mouse orthologue of ARX, a gene mutated in several X-linked forms of mental retardation and epilepsy, is a marker of adult neural stem cells and forebrain GABAergic neurons.	RELN ARX	8.80e-05	6	85	2	15376319
Pubmed	TIM-4 glycoprotein-mediated degradation of dying tumor cells by autophagy leads to reduced antigen presentation and increased immune tolerance.	PIK3R1 PRKAA2	8.80e-05	6	85	2	24315994
Pubmed	Expression patterns of Brx1 (Rieg gene), Sonic hedgehog, Nkx2.2, Dlx1 and Arx during zona limitans intrathalamica and embryonic ventral lateral geniculate nuclear formation.	PITX1 ARX	8.80e-05	6	85	2	9347917
Pubmed	Bacterial MgrB peptide activates chemoreceptor Fpr3 in mouse accessory olfactory system and drives avoidance behaviour.	FPR2 FPR3	1.23e-04	7	85	2	31653840
Pubmed	Coexistence within one cell of microvillous and ciliary phototransductions across M1- through M6-IpRGCs.	ADCY4 OPN4	1.23e-04	7	85	2	38109525
Pubmed	Synergistic contributions of cyclin-dependant kinase 5/p35 and Reelin/Dab1 to the positioning of cortical neurons in the developing mouse brain.	RELN ITPR1	1.23e-04	7	85	2	11226314
Pubmed	Distribution of a reeler gene-related antigen in the developing cerebellum: an immunohistochemical study with an allogeneic antibody CR-50 on normal and reeler mice.	RELN ITPR1	1.23e-04	7	85	2	8863127
Pubmed	Endocytosis, intracellular sorting, and processing of exosomes by dendritic cells.	ITGAL ITGAV	1.23e-04	7	85	2	15284116
Pubmed	Mapping a chromosomal locus for valproic acid-induced exencephaly in mice.	ITGAL TBX6	1.23e-04	7	85	2	15170225
Pubmed	Reelin signals through phosphatidylinositol 3-kinase and Akt to control cortical development and through mTor to regulate dendritic growth.	RELN PIK3R1	1.23e-04	7	85	2	17698586
Pubmed	Formyl peptide receptor-like proteins are a novel family of vomeronasal chemosensors.	FPR2 FPR3	1.23e-04	7	85	2	19387439
Pubmed	Classification and evolutionary analysis of the basic helix-loop-helix gene family in the green anole lizard, Anolis carolinensis.	MLXIPL MLXIP	1.23e-04	7	85	2	23756994
Pubmed	Stereocilin connects outer hair cell stereocilia to one another and to the tectorial membrane.	STRC STRCP1	1.64e-04	8	85	2	21165971
Pubmed	CIP2A Interacts with TopBP1 and Drives Basal-Like Breast Cancer Tumorigenesis.	UBR5 PIK3R1	1.64e-04	8	85	2	34145035
Pubmed	Mapping of transcription start sites of human retina expressed genes.	OPN4 IMPG1 RGR	1.86e-04	45	85	3	17286855
Pubmed	The L1 adhesion molecule is a cellular ligand for VLA-5.	ITGAL ITGAV	2.10e-04	9	85	2	8557754
Pubmed	The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation.	SLC16A2 SLCO4A1	2.10e-04	9	85	2	21486766
Pubmed	Histone demethylase KDM5C is a SAHA-sensitive central hub at the crossroads of transcriptional axes involved in multiple neurodevelopmental disorders.	RELN ARX	2.10e-04	9	85	2	31691806
Pubmed	Branching and nucleokinesis defects in migrating interneurons derived from doublecortin knockout mice.	RELN ARX	2.10e-04	9	85	2	16571605
Pubmed	A disintegrin and metalloproteinase with thrombospondin motifs 2 cleaves and inactivates Reelin in the postnatal cerebral cortex and hippocampus, but not in the cerebellum.	RELN ITPR1	2.10e-04	9	85	2	31491533
Pubmed	Genetic characterization of the murine Ym1 gene and identification of a cluster of highly homologous genes.	OVGP1 CHI3L1	2.10e-04	9	85	2	9828134
Pubmed	Differential expansion of the N-formylpeptide receptor gene cluster in human and mouse.	FPR2 FPR3	2.10e-04	9	85	2	9722950
Pubmed	Clustering of vomeronasal receptor genes is required for transcriptional stability but not for choice.	FPR2 FPR3	2.10e-04	9	85	2	36383665
Pubmed	Developmental and cell type-specific expression of thyroid hormone transporters in the mouse brain and in primary brain cells.	SLC16A2 SLCO4A1	2.10e-04	9	85	2	21264952
Pubmed	All-trans retinoic acid-induced ectopic limb and caudal structures: murine strain sensitivities and pathogenesis.	PITX1 TBX6	2.62e-04	10	85	2	18498097
Pubmed	Physiological significance of proteolytic processing of Reelin revealed by cleavage-resistant Reelin knock-in mice.	RELN ITPR1	2.62e-04	10	85	2	32161359
Pubmed	Comprehensive analysis of the expression patterns of the adenylate cyclase gene family in the developing and adult mouse brain.	ADCY4 RELN	2.62e-04	10	85	2	16615126
Pubmed	Oscillatory flow-induced proliferation of osteoblast-like cells is mediated by alphavbeta3 and beta1 integrins through synergistic interactions of focal adhesion kinase and Shc with phosphatidylinositol 3-kinase and the Akt/mTOR/p70S6K pathway.	PIK3R1 ITGAV	2.62e-04	10	85	2	19889638
Pubmed	Genetic nomenclature for loci controlling surface antigens of mouse hemopoietic cells.	MS4A1 ITGAL ITGAV	3.02e-04	53	85	3	1431091
Pubmed	Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.	STRC STRCP1	3.20e-04	11	85	2	31448880
Pubmed	gp120- and TNF-alpha-induced modulation of human B cell function: proliferation, cyclic AMP generation, Ig production, and B-cell receptor expression.	ADCY4 MS4A1	3.20e-04	11	85	2	10808179
Pubmed	Otogelin, otogelin-like, and stereocilin form links connecting outer hair cell stereocilia to each other and the tectorial membrane.	STRC STRCP1	3.20e-04	11	85	2	31776257
Pubmed	Chemosensory Cell-Derived Acetylcholine Drives Tracheal Mucociliary Clearance in Response to Virulence-Associated Formyl Peptides.	FPR2 FPR3	3.83e-04	12	85	2	32294408
Pubmed	Zinc-finger gene Fez in the olfactory sensory neurons regulates development of the olfactory bulb non-cell-autonomously.	RELN ARX	3.83e-04	12	85	2	16540508
Cytoband	4q31.22	ZNF827 SLC10A7	1.51e-04	10	85	2	4q31.22
Cytoband	19q13.3-q13.4	FPR2 FPR3	2.61e-04	13	85	2	19q13.3-q13.4
Cytoband	1p31	PRKAA2 SRSF11	6.95e-04	21	85	2	1p31
Cytoband	15q15.3	STRC STRCP1	9.89e-04	25	85	2	15q15.3
GeneFamily	Formyl peptide receptors	FPR2 FPR3	2.52e-05	3	53	2	198
GeneFamily	Chitinases	OVGP1 CHI3L1	1.75e-04	7	53	2	816
GeneFamily	Opsin receptors	OPN4 RGR	4.56e-04	11	53	2	215
GeneFamily	CD molecules\|Integrin alpha subunits	ITGAL ITGAV	1.25e-03	18	53	2	1160
GeneFamily	CD molecules\|Mucins	OVGP1 MUC16	1.71e-03	21	53	2	648
ToppCell	facs-Lung-Endomucin-24m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM OVGP1 DRAXIN FPR2 SLCO4A1 TBX6	5.93e-07	158	85	6	0ed844ab625351a46b74edddf082279ed1bae5c6
ToppCell	facs-Lung-Endomucin-24m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM OVGP1 DRAXIN FPR2 SLCO4A1 TBX6	5.93e-07	158	85	6	b3a810314e253b4fd0f578e759c36fdd21722934
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPN4 EXPH5 KBTBD8 NAV3 DAAM2 STRC	5.93e-07	158	85	6	f296ca24fdedc33f1d24b79e7660763114ce7fa3
ToppCell	facs-Marrow-T-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	OPN4 EXPH5 KBTBD8 NAV3 DAAM2 STRC	5.93e-07	158	85	6	8c7108f2c40d97a317762ba0b8eca76542b2ebaf
ToppCell	facs-Lung-Endomucin-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EXPH5 PRKAA2 NAV3 F8 PLEKHA8	9.74e-07	172	85	6	b3c4adccc34bb9e4e78e40f4e2e23736c347cc75
ToppCell	facs-Lung-Endomucin-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN EXPH5 PRKAA2 NAV3 F8 PLEKHA8	9.74e-07	172	85	6	2f1673fcb2356684d60871debb0f159aec553a1c
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial-LEC6_(ADAMTS4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 RELN PRKAA2 AGPAT4 CATSPERB F8	1.35e-06	182	85	6	fd786c88826ad3d5cc5c3d80f8e392d6be1b5267
ToppCell	5'-Adult-Appendix-Endothelial-lymphatic_endothelial\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 RELN PRKAA2 AGPAT4 CATSPERB F8	1.44e-06	184	85	6	453295362888c9a59d0e73c7a5b15914c50ff591
ToppCell	Endothelial-endothelial_cell_of_lymph_vessel\|World / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB F8	1.63e-06	188	85	6	80910dcbb51990f2baed240f319456c0d3fa2065
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB F8	1.63e-06	188	85	6	c2805232618a7b6f844d34e37ad458a9923dbfe1
ToppCell	human_hepatoblastoma-Tumor_cells-T5\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	UBR5 MYO10 EXPH5 AGPAT4 ITPR1 SORCS1	1.63e-06	188	85	6	b070a0667f1ee9b825b267b6c389b7c42fc436f9
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB F8	1.63e-06	188	85	6	aeecbc057dc823f8fcea8a98f18d213bacc7f4db
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic-LEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB F8	1.96e-06	194	85	6	f772a9f9ef8635aeaeb8b022dbb94e9672b36ead
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic-LEC-LEC\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB F8	1.96e-06	194	85	6	3b73f2d305a7566f7ab567e5f18c82cd3d80e32c
ToppCell	nucseq-Endothelial-Endothelial_Lymphatic\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB F8	1.96e-06	194	85	6	5d2b3ed5374e2ab10c1c7eb3a03139fc95036a48
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Rxfp1_Eya1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 PITX1 ARX MMP27 LHFPL5	5.89e-06	134	85	5	657ad905b40ec3f82acdef824431b8276d291ef7
ToppCell	Control-APC-like-Transitioning_MDM\|Control / group, cell type (main and fine annotations)	MGAM FPR2 FPR3 KBTBD8 LHFPL5	8.08e-06	143	85	5	ffc1f497245d559e97e40d1bc4ee14e1ef09040c
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW19\|organoid_Tanaka_cellReport / Sample Type, Dataset, Time_group, and Cell type.	DRAXIN PITX1 KBTBD8 LHFPL5 CHI3L1	1.19e-05	155	85	5	9d53caee196b5c2bbc90c4f54f693b64d4086065
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)-\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 RELN KIF26A PRKAA2 F8	1.66e-05	166	85	5	5ba45407a47207ff01e4a3f9f5d91d8247fe9b6f
ToppCell	356C-Endothelial_cells-Endothelial-F_(Lymphatics)\|356C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 RELN KIF26A PRKAA2 F8	1.66e-05	166	85	5	6bd5aa205b6e4b88ba9f8cd0999e2191d7d1d16c
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Myeloid-Mono-Mono_naive-A\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	MGAM PNPLA6 VNN2 FPR2 ITGAL	1.71e-05	167	85	5	1cd9e2af85c6c5b9e1d88991c87ac6980b387243
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D122\|Adult / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 F8	2.03e-05	173	85	5	dba09ba9748871e38a16449d500ae4d7b405c42f
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A3 EXPH5 PIK3R1 USP24 ITPR1	2.03e-05	173	85	5	0c74bdb40e635d906fd180412c23bf7fed61621e
ToppCell	severe_influenza-Neutrophil\|severe_influenza / disease group, cell group and cell class (v2)	MGAM VNN2 FPR2 DAAM2 CHI3L1	2.03e-05	173	85	5	615e266419b9f06e964eff73cb466f05451ba0dd
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB	2.66e-05	183	85	5	bc98df870de65aff6dab295c24cbc199c7f2aa15
ToppCell	COVID-19-Neuronal_cells-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	KIAA1671 ADCY4 RELN CATSPERB F8	2.80e-05	185	85	5	4a095829992b39856a73bdfac03ee68b9aa0d3b8
ToppCell	COVID-19-Neuronal_cells\|COVID-19 / group, cell type (main and fine annotations)	KIAA1671 ADCY4 RELN CATSPERB F8	2.80e-05	185	85	5	36ce23893915f5c380cca39b2c33a516edf31c3a
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MLXIPL RELN MS4A1 ITGAV TP53INP2	3.02e-05	188	85	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 F8	3.10e-05	189	85	5	0d18ea72bd58d32a8ab9a61cf97f5786642f804b
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_lymph_vessel\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 F8	3.10e-05	189	85	5	55a1776a4ce049959b3f13a43744c7314bc1f00a
ToppCell	Children_(3_yrs)-Endothelial-endothelial_cell_of_lymph_vessel-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	KIAA1671 ADCY4 RELN PRKAA2 CATSPERB	3.18e-05	190	85	5	6e6ce6dd549d1c38cfef5b3f8be06ab01ce344b7
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel\|Adult / Lineage, Cell type, age group and donor	ADCY4 RELN PRKAA2 CATSPERB F8	3.18e-05	190	85	5	91bf3b7e9148589757436a53a4f58e0ebfe54400
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A3 EXPH5 PIK3R1 USP24 ITPR1	3.60e-05	195	85	5	60d08fb27469d1e247bc47b651d7023ba82cf92f
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_1\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A3 EXPH5 PIK3R1 USP24 ITPR1	3.60e-05	195	85	5	a38d9dc6192aea673d96fda6b25e81223fda3abf
ToppCell	(1)_Control_(PBS)-(1)_VE-Cad+_vascular_cells\|World / Stress and Cell class	KIAA1671 ADCY4 MYO10 F8 SBNO2	3.60e-05	195	85	5	6b5d3ecec0c00ebfc889dc6235390ff53b5c0b6a
ToppCell	facs-GAT-Fat-3m-Endothelial\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 ADCY4 RELN KIF26A MYO10	3.69e-05	196	85	5	b6cc1f466d45479764080d34b1daeb8243a5a9f3
ToppCell	facs-GAT-Fat-3m-Endothelial-endothelial_cell\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 ADCY4 RELN KIF26A MYO10	3.69e-05	196	85	5	ede6104cdfa4ee5287efcca9bbc36677cbf7a8d8
ToppCell	facs-GAT-Fat-3m-Endothelial-nan\|GAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KIAA1671 ADCY4 RELN KIF26A MYO10	3.69e-05	196	85	5	039044ab28c53391c34d8226fb8cf78549e63ef4
ToppCell	Bronchus_Control_(B.)-Stromal-TX-Mesothelial-1\|Bronchus_Control_(B.) / Sample group, Lineage and Cell type	DRAXIN SLC16A2 DAAM2 CHI3L1 F8	3.87e-05	198	85	5	9b1a58fcf818f9c4ae57bbe99655f0a64fe87df7
ToppCell	Frontal_cortex-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Sst\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	MASP1 ARX NCMAP GAA	4.21e-05	101	85	4	cf52c93f523c5f25bd45519a1444ce7bd1d8b577
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN ARX LHFPL5	7.98e-05	119	85	4	e868453c02dcf0e07821886b81ca739887d43c67
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Nr2f2_Necab1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN MS4A1 ARX	9.36e-05	124	85	4	298ff8bd8f0459f44ce8a8aea889c6f1cf84ac5f
ToppCell	LPS-IL1RA-Myeloid-Monocytes,_Macrophages-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF26A SLCO4A1 EXTL1 NCMAP	1.45e-04	139	85	4	505bf5a483fc2ba69377db9850c3b26ab2f416d1
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Tac2_Tacstd2\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN ARX LHFPL5	1.62e-04	143	85	4	24fd24846fbef049af669a57d42fcc18928d2b27
ToppCell	Nasal_Brush-Epithelial-Club\|Epithelial / Tissue, Lineage and Cell class of Lung Cells from 10X	NYNRIN STRC DMBT1 TBX6	1.95e-04	150	85	4	d39d73a1de6a873292d48e469d9403f513045be3
ToppCell	droplet-Kidney-nan-24m-Lymphocytic-CD45____macrophage\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AGPAT4 CHI3L1 ITGAL TBX6	1.95e-04	150	85	4	34774b015adecc2be56a471fda8994e89a6ad93e
ToppCell	Nasal_Brush-Epithelial-Club\|Nasal_Brush / Tissue, Lineage and Cell class of Lung Cells from 10X	NYNRIN STRC DMBT1 TBX6	1.95e-04	150	85	4	c68645ffcffe524cf1d9736cf72a15b37ed8dc3d
ToppCell	Healthy_donor-B_cell\|World / disease group, cell group and cell class (v2)	MS4A1 PITX1 STRC TBX6	1.95e-04	150	85	4	a2dfed562de7f58f902b547acec5a13853c80c4c
ToppCell	Healthy_donor-B_cell\|Healthy_donor / disease group, cell group and cell class (v2)	MS4A1 PITX1 STRC TBX6	2.05e-04	152	85	4	5768edfde8010324d8594815e73bbfba2c3045f3
ToppCell	LPS-IL1RA-Myeloid_granulocytic\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEATR4 NYNRIN ITGAL TP53INP2	2.15e-04	154	85	4	d55fb73461885e1e02061a344ff89624ef4de487
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Crhr2_Efemp1\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN ARX LHFPL5	2.15e-04	154	85	4	a2adaa4a6cd8708cd579b8efbeb4ff2131c5482e
ToppCell	E18.5-samps-Endothelial-Mature_fetal_endothelial-capillary_endothelial_Hpgd-CA4_high\|E18.5-samps / Age Group, Lineage, Cell class and subclass	ADCY4 PNPLA6 SLC12A3 MUC16	2.15e-04	154	85	4	212c340a096a3a9669d1aebd61c045cf1402a868
ToppCell	LPS-IL1RA-Myeloid_granulocytic-Neutrophils\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	HEATR4 NYNRIN ITGAL TP53INP2	2.15e-04	154	85	4	43735f7c58cac51855ded486ee8d8729a1b9909e
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NYNRIN ALG9 CC2D2A TBX6	2.26e-04	156	85	4	c11ca6b1b5029c15aab91273cece70a487287839
ToppCell	facs-Brain_Myeloid-Striatum_-18m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FPR2 DAAM2 ITGAL	2.32e-04	157	85	4	9d4308312301cb922f156a7b6aededc9e1c62807
ToppCell	LPS-IL1RA-Stromal_mesenchymal-Fibroblasts-Pericyte_2\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	STRC CHI3L1 TP53INP2 F8	2.38e-04	158	85	4	7f5426585d0d299d2b48e5fcb349950feffdef33
ToppCell	droplet-Kidney-KIDNEY-30m-Lymphocytic-Epcam____proximal_tube_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MS4A1 YLPM1 SLCO4A1 TMEM18	2.38e-04	158	85	4	1d78578dc1f8ba43dacdccae1082c0b9d749f64d
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN ARX DAAM2	2.49e-04	160	85	4	dd16ca90feb3ae88b6409d6c278b4765da565514
ToppCell	frontal_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Calb2_Pdlim5\|frontal_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	MASP1 RELN ARX DAAM2	2.55e-04	161	85	4	bf70be1de418615b5442ec684552551edaf1f072
ToppCell	droplet-Marrow-nan-18m-Lymphocytic-NK_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ADCY4 KBTBD8 ITGAL ITGAV	2.55e-04	161	85	4	3f3a2148c8d65e6a06f8d8116a3aa58dda17d618
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell-kidney_distal_convoluted_tubule_epithelial_cell-Distal_Convoluted_Tubule_Cell_Type_2\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	SLC12A3 EXPH5 PRKAA2 ITPR1	2.61e-04	162	85	4	36ddebe3bb172c992739353b7b049b2dde98b559
ToppCell	367C-Lymphocytic-ILC-ILC-1\|367C / Donor, Lineage, Cell class and subclass (all cells)	DRAXIN ZNF827 PIK3R1 TBX6	2.61e-04	162	85	4	74cd0de957fdbe527656befd61f67d6814ce9e98
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM OVGP1 FPR2 SBNO2	2.80e-04	165	85	4	84eca6a0f5e996b6955ae79fa102af239098fe8f
ToppCell	facs-Heart-LV-3m-Mesenchymal-atrial_myocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM OVGP1 FPR2 SBNO2	2.80e-04	165	85	4	af59a095ecc6758abc13d763c00e44447c488167
ToppCell	droplet-Lung-30m-Hematologic-myeloid-intermediate_monocyte-intermediate_monocyte_l4\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FPR2 AGPAT4 ITGAL ITGAV	2.87e-04	166	85	4	1a3a15d1fc76bb91d832cdc6e3da0a6140b94b75
ToppCell	facs-Trachea-nan-18m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PIK3R1 DAAM2 CHI3L1 NCMAP	2.93e-04	167	85	4	7b1fd19946cee67dae68f0f0d98420abcd532482
ToppCell	Posterior_cortex-Neuronal-Inhibitory\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	RELN ARX LHFPL5 GAA	2.93e-04	167	85	4	9a84f45345c75f2c8ff38a04245aadee2a26a240
ToppCell	PND03-Mesenchymal-Mesenchymal_myocytic-Myofibroblast_airway-ASMC-ASMC_prolif\|PND03 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	MASP1 OPN4 PRKAA2 ITPR1	2.93e-04	167	85	4	91b14df450bfb6a2b406c88f8c75cd51eeb9e82b
ToppCell	droplet-Pancreas-Exocrine-24m-Epithelial-pancreatic_acinar_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLCO4A1 EXTL1 DMBT1 PLEKHA8	2.93e-04	167	85	4	3c06894fc6177f3c204094719904da42f08b9af8
ToppCell	367C-Lymphocytic-ILC-ILC-1\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	DRAXIN ZNF827 PIK3R1 TBX6	3.00e-04	168	85	4	80233a13135fd159f5764336a1fe67fba237776b
ToppCell	healthy_donor-Myeloid-Monocytic-Neutrophil\|healthy_donor / Disease condition, Lineage, Cell class and subclass	MGAM VNN2 FPR2 CHI3L1	3.00e-04	168	85	4	04259f5a9b067cd1b5619e34591e4b2fccc18535
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM PITX1 KBTBD8 DMBT1	3.07e-04	169	85	4	421fb287c7e439d1870b7950c5e3ca34106e014a
ToppCell	facs-Heart-LA-18m-Myeloid-macrophage\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM PITX1 KBTBD8 DMBT1	3.07e-04	169	85	4	383639ec4f9d0c6255e0881edca15cdd1980a37c
ToppCell	Influenza_Severe-Neutrophil\|World / Disease group and Cell class	MGAM VNN2 FPR2 DAAM2	3.07e-04	169	85	4	6e8e2580e19c96bcf7fa6a6d8c183df65f428396
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FPR2 CHI3L1 TP53INP2	3.21e-04	171	85	4	ab21f20ec041cbaacccbd7da4dccdb77ec8bc5c6
ToppCell	facs-Marrow-Granulocytes-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MGAM FPR2 CHI3L1 TP53INP2	3.21e-04	171	85	4	97ad2cfff568a9d006ab1d2e6e00946ee4e3beb3
ToppCell	3'_v3-GI_small-bowel-Lymphocytic_NK-NK_CD16\|GI_small-bowel / Manually curated celltypes from each tissue	MGAM LIM2 AGPAT4 DMBT1	3.28e-04	172	85	4	701de463f85aaad3a4b36a0d5fbc416406620089
ToppCell	CTRL-Myeloid-Neutrophil\|CTRL / Disease state, Lineage and Cell class	MGAM VNN2 FPR2 CHI3L1	3.28e-04	172	85	4	ef3a6fe3b7300959f9f71130200c7fb8741c42b0
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)-\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8 ITPR1	3.35e-04	173	85	4	ec88e871b49331fca59bc610a8ae58e2d5e76bc1
ToppCell	facs-Trachea-nan-24m-Mesenchymal-chondrocyte\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SLC16A2 EXTL1 CHI3L1 NCMAP	3.35e-04	173	85	4	2226505610af1becc253d0a5550627144ef0ed6b
ToppCell	368C-Endothelial_cells-Endothelial-B_(Artery)\|368C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 SLCO4A1 F8 ITPR1	3.35e-04	173	85	4	22200fe74e33e2beae0eed289ca8476bbc0b1b2d
ToppCell	356C-Lymphocytic-NK_cells-NK_cell_E\|NK_cells / Donor, Lineage, Cell class and subclass (all cells)	MYO10 USP40 SLCO4A1 CHI3L1	3.35e-04	173	85	4	090dc3c5bd2652a65c2490fc889da858c3af368f
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ZGRF1 NYNRIN ARX CC2D2A	3.43e-04	174	85	4	e2243f1e48e3275753a2b3a69d06eefce69a8ded
ToppCell	ASK428-Immune-B_cell\|ASK428 / Donor, Lineage and Cell class of Lung cells from Dropseq	MS4A1 SLCO4A1 MUC16 SRSF11	3.43e-04	174	85	4	b5a7a612a515736cf3489afd0f6ad2054d54526f
ToppCell	343B-Myeloid-Macrophage-FABP4+_Macrophage\|343B / Donor, Lineage, Cell class and subclass (all cells)	PNPLA6 FPR2 FPR3 DEPDC5	3.50e-04	175	85	4	d3890bd0c570bb81434fdd1c5229891cefe2e462
ToppCell	3'-GW_trimst-2-SmallIntestine-Endothelial-lymphatic_endothelial-LEC3_(ADGRG3+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 RELN KIF26A F8	3.50e-04	175	85	4	43be63976da5ad0764d24d90919a77ce46068f52
ToppCell	ASK428-Immune-B_cell\|Immune / Donor, Lineage and Cell class of Lung cells from Dropseq	MS4A1 EXPH5 SLCO4A1 MUC16	3.50e-04	175	85	4	e0979e5795a49b4e5c9b88e7fe6b7bda7a413a6c
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l34\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SLC16A2 EXTL1 CHI3L1 NCMAP	3.58e-04	176	85	4	77c3da2eaa072a6baefb5087fd07ec18c5e271cd
ToppCell	PBMC-Convalescent-Lymphocyte-B-B_cell-B_naive-B_activate-7\|Convalescent / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	MS4A1 USP40 TP53INP2 TBX6	3.58e-04	176	85	4	dde46f06f6fc3f7ba83be91a0ee6231790955e3e
ToppCell	3'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 RELN AGPAT4 F8	3.66e-04	177	85	4	dfaed388926ce050730492a532824af68bf4feff
ToppCell	facs-Liver-Non-hepatocytes\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	AGPAT4 MLXIP ITGAL F8	3.66e-04	177	85	4	f73ed860685a724591d0f543a9ac4e868aff92f5
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARX AGPAT4 ITPR1 SORCS1	3.66e-04	177	85	4	1dc69c661e70e7e22bd9d7cf953eb638da9fd43c
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1-Pericyte\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MASP1 OPN4 MYO10 DAAM2	3.66e-04	177	85	4	68263456a3c93cd195b321b309ff59e156d732fe
ToppCell	5'-Adult-LargeIntestine-Endothelial-lymphatic_endothelial-LEC1_(ACKR4+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ADCY4 RELN PRKAA2 F8	3.66e-04	177	85	4	b1775e05c28883a15c56628028770bc59d3233fb
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_A_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ARX AGPAT4 ITPR1 SORCS1	3.66e-04	177	85	4	426a9845df7fd13b02e744532c336c60bc4d4a22
ToppCell	cellseq2-Mesenchymal-Myocytic-Myocytic_1\|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	MASP1 OPN4 MYO10 DAAM2	3.66e-04	177	85	4	e415e448c37adc102d766235e9953dec32c021f1
ToppCell	droplet-Fat-SCAT-30m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RELN DRAXIN DAAM2 NCMAP	3.74e-04	178	85	4	5cf12927f0756c4d8a289fe4308d736382e6212e
ToppCell	390C-Endothelial_cells-Endothelial-E-\|390C / Donor, Lineage, Cell class and subclass (all cells)	ADCY4 KIF26A ZGRF1 SLCO4A1	3.74e-04	178	85	4	804ac3725c1f88e2212172bfb9aa01d97a735621
ToppCell	Adult-Endothelial-endothelial_cell_of_lymph_vessel-D231\|Adult / Lineage, Cell type, age group and donor	ADCY4 RELN PRKAA2 F8	3.74e-04	178	85	4	c80ca7a2d3f976089a5e71d0cd9ba9a1c0bd2815
ToppCell	3'-Parenchyma_lung-Endothelial-Lymphatic_EC-endothelial_cell_of_lymphatic_vessel-Lymphatic_EC_differentiating-Lymphatic_EC_differentiating_L.2.5.1.1\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ADCY4 RELN NAV3 F8	3.74e-04	178	85	4	ad3de3e03a401dac64431a541899445262246347
Drug	AC1Q6JQD	HEXA PIK3R1 FPR2 FPR3	1.60e-07	14	83	4	CID000124337
Drug	valiolamine	HEXA MGAM GAA	1.30e-05	13	83	3	CID000174312
Drug	calcium citrate	MGAM F8	1.31e-05	2	83	2	CID000013136
Drug	Miglitol	MGAM GAA	1.31e-05	2	83	2	DB00491
Drug	Fp-O	HEXA GK2 PNPLA6 FPR2 FPR3	1.67e-05	87	83	5	CID000024267
Disease	autosomal recessive nonsyndromic deafness 16 (implicated_via_orthology)	STRC STRCP1	8.01e-06	2	84	2	DOID:0110471 (implicated_via_orthology)
Disease	Autosomal Dominant Lateral Temporal Lobe Epilepsy	RELN DEPDC5	2.40e-05	3	84	2	C1838062
Disease	fish oil supplement exposure measurement, low density lipoprotein cholesterol measurement	MLXIPL USP24	4.79e-05	4	84	2	EFO_0004611, EFO_0600007
Disease	Malformation of cortical development	RELN ARX	1.19e-04	6	84	2	cv:C1955869
Disease	Lissencephaly	RELN ARX	1.19e-04	6	84	2	cv:C0266463
Disease	retinitis pigmentosa (is_implicated_in)	IMPG1 CC2D2A RGR	2.19e-04	41	84	3	DOID:10584 (is_implicated_in)
Disease	mean reticulocyte volume	MLXIPL PIK3R1 NYNRIN ALG9 CC2D2A DBR1 MLXIP SBNO2 TBX6	4.50e-04	799	84	9	EFO_0010701
Disease	sexual dimorphism measurement	MGAM MLXIPL ADCY4 SLC12A3 PIK3R1 NYNRIN PITX1 MLXIP TP53INP2 TMEM18	1.18e-03	1106	84	10	EFO_0021796
Disease	thrombin activatable fibrinolysis inhibitor activation peptide measurement	KBTBD8 ITPR1	1.33e-03	19	84	2	EFO_0008582
Disease	Glioma	PIK3R1 DMBT1 CHI3L1	1.99e-03	87	84	3	C0017638
Disease	osteoarthritis, hip	MASP1 PIK3R1 MLXIP	2.33e-03	92	84	3	EFO_1000786
Disease	glucocorticoid receptor gene expression measurement	PLEKHA8P1 PLEKHA8	2.68e-03	27	84	2	EFO_0600079

Protein segments in the cluster

Peptide	Gene	Start	Entry
SGFGPIMRFSTTTSS	MLLT6	401	P55198
IFRFPSSFSSPVGMV	CATSPERB	401	Q9H7T0
SSVSPRLGSHTMDFF	PRKAA2	526	P54646
TGMFCSSSAFLPSSF	ALG9	181	Q9H6U8
AMAITSLFFFPTSSD	ADCY4	676	Q8NFM4
FRRMSSLVGPTQSFF	MS4A1	31	P11836
SPVEMFLTSAFLTGF	ARIH2OS	166	Q8N7S6
SAGSSIFSMSFPFLI	SLC16A2	236	P36021
PVMSDFITVSSFSFS	DAAM2	911	Q86T65
AFFMEFVRSPRTASS	DEPDC5	1091	O75140
FITFSSAFPLVRMTE	MMP27	11	Q9H306
RLSTFPFVTGSTEMA	MUC16	5846	Q8WXI7
TGITSFPESRFTMSV	MUC16	10241	Q8WXI7
SSSVPFTSIFSQLFM	SLC10A7	161	Q0GE19
PVTSMFTGSAFNRSI	PNPLA6	1056	Q8IY17
TFSRISRPFSAGIMF	LIM2	91	P55344
SRPFSAGIMFFSSTL	LIM2	96	P55344
FLRPSSSTMILFETT	KIAA1671	136	Q9BY89
IVMSIVTTFFSSPFS	ITPR1	1491	Q14643
EAPPFFMASSIFSLT	IMPG1	446	Q17R60
DFSFTATLPFLIVSM	FPR2	71	P25090
LGFTFSDMFIRISTR	MGAM	1111	O43451
DFSFSAILPFRMVSV	FPR3	71	P25089
FSSIPSRAFKTAMFF	LHFPL5	86	Q8TAF8
MGIPTFGRSFTLASS	CHI3L1	256	P36222
SGTSRFIHTDPSRFM	NAV3	766	Q8IVL0
SLMATLSSSNPFFVR	MYO10	621	Q9HD67
KPTPFSSRMSFRSSF	EXPH5	111	Q8NEV8
STGPSAAASFFIRAM	KIF26A	296	Q9ULI4
TLTLFPFSGETVFMS	F8	686	P00451
TSLGRTFIMFFTLGS	KCNU1	286	A8MYU2
EVIPTFFSTMNTSFS	PLEKHA8	306	Q96JA3
TIKSSRTLGSPMYFF	OR4C11	46	Q6IEV9
EIFSPMLFRFSAASS	PIK3R1	266	P27986
FTSIFIPRFLTSMTT	OR6C4	71	Q8NGE1
PLGDTTFFSLNMTTR	NCMAP	6	Q5T1S8
TFPMFISESFGSSRL	RELN	706	P78509
ISPYFRSMFTSGLTE	KBTBD8	71	Q8NFY9
DFLMSFTQAPVFFTS	OPN4	116	Q9UHM6
FSSSRSIFGSMLPAS	MLXIP	336	Q9HAP2
SFFNFAMPLFITITS	RGR	181	P47804
STSLAPTMFFLTTFE	DRAXIN	181	Q8NBI3
PTMFFLTTFEAAPAT	DRAXIN	186	Q8NBI3
PIPSTSRTGFAEFSM	CC2D2A	86	Q9P2K1
IFSSLPLGFFIVSSM	GK2	526	Q14410
FAVDFFVPSASSRMF	ITGAV	51	P06756
MFDFSFPTPASAGTR	TMEM132E-DT	1	A2RUQ5
LFFSTMRTGFLAPTS	TMEM63B	696	Q5T3F8
SERTFFSPIMSSPSG	HEATR4	1006	Q86WZ0
MGYTATLTRTTPTFF	GAA	146	P10253
VVLSPGSFMSITFRS	MASP1	106	P48740
FGRLFSTMAPLTSAS	ARX	481	Q96QS3
FSASFSDVRILPGSM	DBR1	461	Q9UK59
GSFTSSSNFMSIRFI	DMBT1	2086	Q9UGM3
SFSSSTRPGQMEISF	LGSN	256	Q5TDP6
TIPSNFTALSFFMGF	NYNRIN	1086	Q9P2P1
NFGTSRFTTMLSTFA	OVGP1	101	Q12889
FFSFIDGCSSSTMAP	OR4C5	86	Q8NGB2
MSTFFLEVSSVFPDF	HEXA	301	P06865
PAPLSTKSFTFFNSM	PITX1	191	P78337
VIPTFFSTMNTSFSD	PLEKHA8P1	191	O95397
TMFFQDFRPFLSSSP	RNF115	81	Q9Y4L5
FSSDSRPFMSSASFL	SBNO2	51	Q9Y2G9
MALLSGFFFFAPASS	ITGAL	11	P20701
SISINFPSFFTTVMT	MRGPRX2	96	Q96LB1
RPLFESFNGMVSTAS	MLXIPL	776	Q9NP71
SFPERMVGFLTSSHF	EXTL1	516	Q92935
TFLANISSSFEPGRM	STRC	61	Q7RTU9
GMSTFSPKFLESQFS	SLCO4A1	401	Q96BD0
FSSRSLGSLPAFAMF	nan	26	Q8IZM0
TASTRFEMFSLSGTF	VNN2	421	O95498
PFSIFKSDTSSEMFT	WDR88	421	Q6ZMY6
MFQRLSSLFFSTPSP	TP53INP2	1	Q8IXH6
SSALSAFPDIMFSRA	SPATA46	16	Q5T0L3
SPSASSEQMRTLFGF	SRSF11	41	Q05519
FGMFSIFFPSATGIL	SLC12A3	341	P55017
MASFRFPETTFISVT	TBX6	236	O95947
TPAAPSSSGFMSFRE	YLPM1	41	P49750
TEETMRFESFSSPFS	ZNF827	231	Q17R98
SILESLFRSFAPGMS	USP24	1156	Q9UPU5
LFRSFAPGMSTFRVL	USP24	1161	Q9UPU5
ERNAMDFSSVFSPSF	ZGRF1	186	Q86YA3
TFLANISSSFEPGRM	STRCP1	61	A6NGW2
TFFSRGLSFSMSSAI	TMEM42	86	Q69YG0
PFFQFLVSMIRSGSS	AGPAT4	321	Q9NRZ5
TLEGSISFRFTSEGM	SORCS1	936	Q8WY21
APSSSQLFLFFAMGS	USP40	836	Q9NVE5
FDSRGMFISIVFSAP	TMEM18	86	Q96B42
PFFRRSDSMTFLGCI	UBR5	2021	O95071
MADSSSSSFFPDFGL	NLRP14	1	Q86W24