Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	3-phosphoinositide-dependent protein kinase binding	PTK2B INSR	2.07e-05	3	53	2	GO:0043423
GeneOntologyMolecularFunction	ATP-dependent chromatin remodeler activity	CHD5 CHD1 CHD3	1.29e-04	37	53	3	GO:0140658
GeneOntologyMolecularFunction	TAP complex binding	HLA-A HLA-E	2.46e-04	9	53	2	GO:0062061
GeneOntologyMolecularFunction	CD8 receptor binding	HLA-A HLA-E	2.46e-04	9	53	2	GO:0042610
GeneOntologyMolecularFunction	TAP1 binding	HLA-A HLA-E	3.07e-04	10	53	2	GO:0046978
GeneOntologyMolecularFunction	TAP2 binding	HLA-A HLA-E	3.07e-04	10	53	2	GO:0046979
GeneOntologyMolecularFunction	TAP binding	HLA-A HLA-E	3.07e-04	10	53	2	GO:0046977
GeneOntologyMolecularFunction	beta-2-microglobulin binding	HLA-A HLA-E	4.49e-04	12	53	2	GO:0030881
GeneOntologyMolecularFunction	protein tyrosine kinase activity	PTK2B BTK INSR ROS1	5.93e-04	145	53	4	GO:0004713
GeneOntologyMolecularFunction	insulin receptor substrate binding	PTPN11 INSR	7.10e-04	15	53	2	GO:0043560
GeneOntologyMolecularFunction	natural killer cell lectin-like receptor binding	HLA-A HLA-E	9.16e-04	17	53	2	GO:0046703
GeneOntologyMolecularFunction	cell adhesion molecule binding	PTPN11 VWF DST MACF1 FGG CDH15 SFN	9.83e-04	599	53	7	GO:0050839
GeneOntologyMolecularFunction	T cell receptor binding	HLA-A HLA-E	1.27e-03	20	53	2	GO:0042608
GeneOntologyMolecularFunction	structural molecule activity	KRT10 VWF DST MAP1B INSR MACF1 FGG CRYBG3	2.27e-03	891	53	8	GO:0005198
GeneOntologyBiologicalProcess	peptidyl-tyrosine autophosphorylation	PTK2B INSR ROS1	2.25e-05	22	52	3	GO:0038083
GeneOntologyBiologicalProcess	positive regulation of CD8-positive, alpha-beta T cell proliferation	HLA-A HLA-E	6.20e-05	5	52	2	GO:2000566
GeneOntologyBiologicalProcess	cell-substrate junction assembly	PTK2B PTPN11 DST MACF1	1.59e-04	108	52	4	GO:0007044
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent	HLA-A HLA-E	1.73e-04	8	52	2	GO:0002485
GeneOntologyBiologicalProcess	cell-substrate junction organization	PTK2B PTPN11 DST MACF1	2.02e-04	115	52	4	GO:0150115
GeneOntologyBiologicalProcess	growth	PTK2B PTPN11 SEMA6D MAP1B INSR HLA-E KCNK2 MACF1 ROS1 KAT2A SFN	2.11e-04	1235	52	11	GO:0040007
GeneOntologyBiologicalProcess	protection from natural killer cell mediated cytotoxicity	HLA-A HLA-E	2.22e-04	9	52	2	GO:0042270
GeneOntologyBiologicalProcess	integrin-mediated signaling pathway	PTK2B PTPN11 DST FYB1	2.70e-04	124	52	4	GO:0007229
GeneOntologyBiologicalProcess	regulation of CD8-positive, alpha-beta T cell proliferation	HLA-A HLA-E	2.77e-04	10	52	2	GO:2000564
GeneOntologyBiologicalProcess	positive regulation of CD8-positive, alpha-beta T cell activation	HLA-A HLA-E	2.77e-04	10	52	2	GO:2001187
GeneOntologyBiologicalProcess	regulation of innate immune response	PTPN11 HLA-A GPATCH3 BTK HLA-E SFN LILRA4	3.08e-04	519	52	7	GO:0045088
GeneOntologyBiologicalProcess	regulation of immune response	PTPN11 HLA-A GPATCH3 BTK HLA-E C8A IL1R1 FYB1 SFN LILRA4	3.27e-04	1085	52	10	GO:0050776
GeneOntologyBiologicalProcess	CD8-positive, alpha-beta T cell proliferation	HLA-A HLA-E	3.38e-04	11	52	2	GO:0035740
GeneOntologyBiologicalProcess	negative regulation of type I interferon production	PTPN11 GPATCH3 LILRA4	3.42e-04	54	52	3	GO:0032480
GeneOntologyBiologicalProcess	regulation of response to external stimulus	PTK2B PTPN11 VWF HLA-A GPATCH3 BTK HLA-E FGG IL1R1 SFN LILRA4	3.65e-04	1316	52	11	GO:0032101
GeneOntologyBiologicalProcess	regulation of cytokine production involved in immune response	HLA-A BTK HLA-E IL1R1	4.88e-04	145	52	4	GO:0002718
GeneOntologyBiologicalProcess	cell junction assembly	PTK2B PTPN11 DST MAP1B MACF1 SDK1 CDH15	5.34e-04	569	52	7	GO:0034329
GeneOntologyBiologicalProcess	positive regulation of lymphocyte mediated immunity	HLA-A BTK HLA-E IL1R1	5.55e-04	150	52	4	GO:0002708
GeneOntologyBiologicalProcess	positive regulation of adaptive immune response based on somatic recombination of immune receptors built from immunoglobulin superfamily domains	HLA-A BTK HLA-E IL1R1	5.55e-04	150	52	4	GO:0002824
GeneOntologyBiologicalProcess	positive regulation of nitric oxide biosynthetic process	PTK2B INSR HLA-E	5.91e-04	65	52	3	GO:0045429
GeneOntologyBiologicalProcess	positive regulation of hypersensitivity	BTK HLA-E	6.41e-04	15	52	2	GO:0002885
GeneOntologyBiologicalProcess	positive regulation of nitric oxide metabolic process	PTK2B INSR HLA-E	6.46e-04	67	52	3	GO:1904407
GeneOntologyBiologicalProcess	cell junction organization	PTK2B PTPN11 DST MAP1B INSR MACF1 ARHGAP39 SDK1 CDH15	6.63e-04	974	52	9	GO:0034330
GeneOntologyBiologicalProcess	positive regulation of production of molecular mediator of immune response	HLA-A BTK HLA-E IL1R1	6.74e-04	158	52	4	GO:0002702
GeneOntologyBiologicalProcess	regulation of growth	PTK2B SEMA6D MAP1B INSR KCNK2 MACF1 ROS1 SFN	6.78e-04	777	52	8	GO:0040008
GeneOntologyBiologicalProcess	positive regulation of adaptive immune response	HLA-A BTK HLA-E IL1R1	6.90e-04	159	52	4	GO:0002821
GeneOntologyBiologicalProcess	response to calcium ion	PTK2B KRT10 FGG D2HGDH	7.23e-04	161	52	4	GO:0051592
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	HLA-A HLA-E	7.31e-04	16	52	2	GO:0002486
GeneOntologyBiologicalProcess	regulation of neuron projection development	PTK2B SEMA6D HLA-A MAP1B FAT3 HLA-E MACF1	8.21e-04	612	52	7	GO:0010975
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	HLA-A HLA-E	8.28e-04	17	52	2	GO:0002484
GeneOntologyBiologicalProcess	keratinocyte development	KRT10 SFN	8.28e-04	17	52	2	GO:0003334
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	HLA-A HLA-E	8.28e-04	17	52	2	GO:0002476
GeneOntologyBiologicalProcess	positive regulation of acute inflammatory response to antigenic stimulus	BTK HLA-E	8.28e-04	17	52	2	GO:0002866
GeneOntologyBiologicalProcess	cytokine production involved in immune response	HLA-A BTK HLA-E IL1R1	8.48e-04	168	52	4	GO:0002367
GeneOntologyBiologicalProcess	positive regulation of T cell mediated immunity	HLA-A HLA-E IL1R1	8.63e-04	74	52	3	GO:0002711
GeneOntologyBiologicalProcess	negative regulation of neuron projection development	SEMA6D HLA-A FAT3 HLA-E	8.67e-04	169	52	4	GO:0010977
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class Ib	HLA-A HLA-E	9.29e-04	18	52	2	GO:0002428
GeneOntologyBiologicalProcess	antigen processing and presentation of exogenous peptide antigen via MHC class I	HLA-A HLA-E	9.29e-04	18	52	2	GO:0042590
GeneOntologyBiologicalProcess	positive regulation of immune system process	PTK2B PTPN11 HLA-A GPATCH3 BTK HLA-E C8A IL1R1 FYB1 LILRA4	9.40e-04	1242	52	10	GO:0002684
GeneOntologyBiologicalProcess	positive regulation of leukocyte mediated immunity	HLA-A BTK HLA-E IL1R1	9.87e-04	175	52	4	GO:0002705
GeneOntologyBiologicalProcess	regulation of hypersensitivity	BTK HLA-E	1.04e-03	19	52	2	GO:0002883
GeneOntologyBiologicalProcess	regulation of response to biotic stimulus	PTPN11 HLA-A GPATCH3 BTK HLA-E SFN LILRA4	1.10e-03	643	52	7	GO:0002831
GeneOntologyBiologicalProcess	regulation of cartilage development	PTPN11 KAT2A PRKG2	1.12e-03	81	52	3	GO:0061035
GeneOntologyCellularComponent	cell surface	KRT10 VWF SEMA6D HLA-A INSR HLA-E KCNK2 ROS1 FGG TMX3 IL1R1	8.84e-05	1111	53	11	GO:0009986
GeneOntologyCellularComponent	MHC class Ib protein complex	HLA-A HLA-E	1.31e-04	7	53	2	GO:0032398
GeneOntologyCellularComponent	MHC class I protein complex	HLA-A HLA-E	2.80e-04	10	53	2	GO:0042612
GeneOntologyCellularComponent	membrane raft	PTPN11 HLA-A BTK INSR HLA-E CDH15	2.99e-04	362	53	6	GO:0045121
GeneOntologyCellularComponent	membrane microdomain	PTPN11 HLA-A BTK INSR HLA-E CDH15	3.08e-04	364	53	6	GO:0098857
GeneOntologyCellularComponent	MHC class I peptide loading complex	HLA-A HLA-E	5.63e-04	14	53	2	GO:0042824
GeneOntologyCellularComponent	plasma membrane protein complex	PTK2B HLA-A INSR HLA-E KCNK2 C8A CDH15 LILRA4	7.57e-04	785	53	8	GO:0098797
GeneOntologyCellularComponent	CHD-type complex	CHD5 CHD3	8.37e-04	17	53	2	GO:0090545
GeneOntologyCellularComponent	NuRD complex	CHD5 CHD3	8.37e-04	17	53	2	GO:0016581
GeneOntologyCellularComponent	cis-Golgi network membrane	HLA-A HLA-E	8.37e-04	17	53	2	GO:0033106
GeneOntologyCellularComponent	Golgi medial cisterna	HLA-A HLA-E	1.54e-03	23	53	2	GO:0005797
GeneOntologyCellularComponent	platelet alpha granule	VWF FGG TMX3	1.70e-03	93	53	3	GO:0031091
GeneOntologyCellularComponent	external side of plasma membrane	VWF HLA-A INSR HLA-E FGG IL1R1	1.94e-03	519	53	6	GO:0009897
GeneOntologyCellularComponent	MHC protein complex	HLA-A HLA-E	1.97e-03	26	53	2	GO:0042611
GeneOntologyCellularComponent	apical dendrite	PTK2B MAP1B	2.98e-03	32	53	2	GO:0097440
Domain	CHDCT2	CHD5 CHD3	2.28e-05	3	52	2	PF08074
Domain	CHDNT	CHD5 CHD3	2.28e-05	3	52	2	PF08073
Domain	DUF1086	CHD5 CHD3	2.28e-05	3	52	2	IPR009462
Domain	DUF1087	CHD5 CHD3	2.28e-05	3	52	2	IPR009463
Domain	CHD_N	CHD5 CHD3	2.28e-05	3	52	2	IPR012958
Domain	CHD_C2	CHD5 CHD3	2.28e-05	3	52	2	IPR012957
Domain	DUF1087	CHD5 CHD3	2.28e-05	3	52	2	PF06465
Domain	DUF1086	CHD5 CHD3	2.28e-05	3	52	2	PF06461
Domain	DUF1087	CHD5 CHD3	2.28e-05	3	52	2	SM01147
Domain	DUF1086	CHD5 CHD3	2.28e-05	3	52	2	SM01146
Domain	Chromo_domain	CHD5 CHD1 CHD3	3.95e-05	24	52	3	IPR023780
Domain	Chromo	CHD5 CHD1 CHD3	5.06e-05	26	52	3	PF00385
Domain	CHROMO_1	CHD5 CHD1 CHD3	6.35e-05	28	52	3	PS00598
Domain	CHROMO_2	CHD5 CHD1 CHD3	6.35e-05	28	52	3	PS50013
Domain	SNF2_N	CHD5 CHD1 CHD3	9.54e-05	32	52	3	IPR000330
Domain	Chromodomain-like	CHD5 CHD1 CHD3	9.54e-05	32	52	3	IPR016197
Domain	SNF2_N	CHD5 CHD1 CHD3	9.54e-05	32	52	3	PF00176
Domain	Chromo/shadow_dom	CHD5 CHD1 CHD3	1.05e-04	33	52	3	IPR000953
Domain	CHROMO	CHD5 CHD1 CHD3	1.05e-04	33	52	3	SM00298
Domain	TyrKc	PTK2B BTK INSR ROS1	1.05e-04	88	52	4	SM00219
Domain	Tyr_kinase_cat_dom	PTK2B BTK INSR ROS1	1.05e-04	88	52	4	IPR020635
Domain	-	DST MACF1	1.13e-04	6	52	2	3.90.1290.10
Domain	MHC_I_a_C	HLA-A HLA-E	1.13e-04	6	52	2	IPR010579
Domain	GAR	DST MACF1	1.13e-04	6	52	2	PS51460
Domain	MHC_I_C	HLA-A HLA-E	1.13e-04	6	52	2	PF06623
Domain	-	DST MACF1	1.13e-04	6	52	2	3.30.920.20
Domain	GAS_dom	DST MACF1	1.13e-04	6	52	2	IPR003108
Domain	GAS2	DST MACF1	1.13e-04	6	52	2	PF02187
Domain	GAS2	DST MACF1	1.13e-04	6	52	2	SM00243
Domain	DNA/RNA_helicase_DEAH_CS	CHD5 CHD1 CHD3	1.25e-04	35	52	3	IPR002464
Domain	PROTEIN_KINASE_TYR	PTK2B BTK INSR ROS1	1.53e-04	97	52	4	PS00109
Domain	Tyr_kinase_AS	PTK2B BTK INSR ROS1	1.53e-04	97	52	4	IPR008266
Domain	Plectin_repeat	DST MACF1	1.58e-04	7	52	2	IPR001101
Domain	Plectin	DST MACF1	1.58e-04	7	52	2	PF00681
Domain	PLEC	DST MACF1	1.58e-04	7	52	2	SM00250
Domain	DEAH_ATP_HELICASE	CHD5 CHD1 CHD3	1.60e-04	38	52	3	PS00690
Domain	Tyr_kinase_rcpt_2_CS	INSR ROS1	4.11e-04	11	52	2	IPR002011
Domain	Pkinase_Tyr	PTK2B BTK INSR ROS1	4.55e-04	129	52	4	PF07714
Domain	-	HLA-A INSR HLA-E ROS1 IL1R1 PKHD1L1 SDK1 LILRA4	4.57e-04	663	52	8	2.60.40.10
Domain	RECEPTOR_TYR_KIN_II	INSR ROS1	4.93e-04	12	52	2	PS00239
Domain	Ser-Thr/Tyr_kinase_cat_dom	PTK2B BTK INSR ROS1	5.87e-04	138	52	4	IPR001245
Domain	Ig-like_fold	HLA-A INSR HLA-E ROS1 IL1R1 PKHD1L1 SDK1 LILRA4	6.92e-04	706	52	8	IPR013783
Domain	Kinase-like_dom	PTK2B DST BTK INSR MACF1 ROS1 PRKG2	7.19e-04	542	52	7	IPR011009
Domain	Chromodomain_CS	CHD1 CHD3	1.13e-03	18	52	2	IPR023779
Domain	MHC_I	HLA-A HLA-E	1.54e-03	21	52	2	PF00129
Domain	MHC_I_a_a1/a2	HLA-A HLA-E	1.54e-03	21	52	2	IPR001039
Domain	Actinin_actin-bd_CS	DST MACF1	1.85e-03	23	52	2	IPR001589
Domain	Spectrin	DST MACF1	1.85e-03	23	52	2	PF00435
Domain	ACTININ_2	DST MACF1	1.85e-03	23	52	2	PS00020
Domain	ACTININ_1	DST MACF1	1.85e-03	23	52	2	PS00019
Domain	-	HLA-A HLA-E	2.02e-03	24	52	2	3.30.500.10
Domain	MHC_I-like_Ag-recog	HLA-A HLA-E	2.02e-03	24	52	2	IPR011161
Domain	Spectrin_repeat	DST MACF1	2.94e-03	29	52	2	IPR002017
Domain	SH3	DST BTK MACF1 FYB1	3.05e-03	216	52	4	PS50002
Domain	SH3_domain	DST BTK MACF1 FYB1	3.26e-03	220	52	4	IPR001452
Domain	Helicase_C	CHD5 CHD1 CHD3	3.30e-03	107	52	3	PF00271
Domain	HELICc	CHD5 CHD1 CHD3	3.30e-03	107	52	3	SM00490
Domain	Helicase_C	CHD5 CHD1 CHD3	3.38e-03	108	52	3	IPR001650
Domain	HELICASE_CTER	CHD5 CHD1 CHD3	3.47e-03	109	52	3	PS51194
Domain	HELICASE_ATP_BIND_1	CHD5 CHD1 CHD3	3.47e-03	109	52	3	PS51192
Domain	DEXDc	CHD5 CHD1 CHD3	3.47e-03	109	52	3	SM00487
Domain	Helicase_ATP-bd	CHD5 CHD1 CHD3	3.56e-03	110	52	3	IPR014001
Domain	Spectrin/alpha-actinin	DST MACF1	3.57e-03	32	52	2	IPR018159
Domain	SPEC	DST MACF1	3.57e-03	32	52	2	SM00150
Domain	Protein_kinase_ATP_BS	PTK2B BTK INSR ROS1 PRKG2	3.98e-03	379	52	5	IPR017441
Domain	MHC_I/II-like_Ag-recog	HLA-A HLA-E	5.01e-03	38	52	2	IPR011162
Pathway	REACTOME_CELL_CELL_COMMUNICATION	PTK2B PTPN11 DST FYB1 SDK1 CDH15	6.07e-06	155	42	6	M522
Pathway	REACTOME_CELL_CELL_COMMUNICATION	PTK2B DST FYB1 SDK1 CDH15	9.19e-06	96	42	5	MM14592
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	PTK2B PTPN11 FYB1	1.34e-05	16	42	3	M925
Pathway	BIOCARTA_NKCELLS_PATHWAY	PTK2B HLA-A HLA-E	5.40e-05	25	42	3	MM1465
Pathway	KEGG_MEDICUS_PATHOGEN_KSHV_MIR1_2_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-E	1.29e-04	6	42	2	M47468
Pathway	KEGG_MEDICUS_PATHOGEN_HTLV_1_P12_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-E	1.80e-04	7	42	2	M47582
Pathway	KEGG_MEDICUS_PATHOGEN_HPV_E5_TO_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-E	1.80e-04	7	42	2	M47530
Pathway	REACTOME_ANTIGEN_PROCESSING_CROSS_PRESENTATION	HLA-A BTK HLA-E FGG	2.71e-04	106	42	4	M518
Pathway	REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY	HLA-A HLA-E	3.08e-04	9	42	2	MM14527
Pathway	REACTOME_SARS_COV_INFECTIONS	PTPN11 HLA-A BTK HLA-E CHD3 IL1R1 SFN	4.35e-04	471	42	7	M39009
Pathway	REACTOME_ENDOSOMAL_VACUOLAR_PATHWAY	HLA-A HLA-E	4.69e-04	11	42	2	M525
Pathway	REACTOME_DAP12_INTERACTIONS	HLA-A BTK HLA-E	5.49e-04	54	42	3	MM14871
Pathway	KEGG_MEDICUS_REFERENCE_ANTIGEN_PROCESSING_AND_PRESENTATION_BY_MHC_CLASS_I_MOLECULES	HLA-A HLA-E	5.61e-04	12	42	2	M47529
Pathway	KEGG_NATURAL_KILLER_CELL_MEDIATED_CYTOTOXICITY	PTK2B PTPN11 HLA-A HLA-E	7.18e-04	137	42	4	M5669
Pathway	REACTOME_SIGNAL_REGULATORY_PROTEIN_FAMILY_INTERACTIONS	PTK2B FYB1	7.71e-04	14	42	2	MM15011
Pathway	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FGG	8.88e-04	15	42	2	M12101
Pathway	REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FGG	8.88e-04	15	42	2	M1262
Pathway	REACTOME_PROLACTIN_RECEPTOR_SIGNALING	CUL1 PTPN11	8.88e-04	15	42	2	M552
Pathway	REACTOME_GRB2_SOS_PROVIDES_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FGG	8.88e-04	15	42	2	MM14959
Pathway	REACTOME_P130CAS_LINKAGE_TO_MAPK_SIGNALING_FOR_INTEGRINS	VWF FGG	8.88e-04	15	42	2	MM14961
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	ZNF610 FAT3 CHD5 MACF1 RARS2 CHD3 KAT2A CRYBG3 TMX3 PCMTD1 AKAP8L CDH15	8.90e-08	1116	53	12	31753913
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	KRT10 DST GLS2 MAP1B CHD5 EIF4B ANKRD30B MACF1 CHD3 KAT2A IL1R1 AKAP8L SFN	1.81e-07	1442	53	13	35575683
Pubmed	Paternal MHC expression on mouse trophoblast affects uterine vascularization and fetal growth.	VWF HLA-A HLA-E	2.79e-07	9	53	3	21300875
Pubmed	MHC class I limits hippocampal synapse density by inhibiting neuronal insulin receptor signaling.	HLA-A INSR HLA-E	3.98e-07	10	53	3	25164678
Pubmed	Constitutive MHC class I molecules negatively regulate TLR-triggered inflammatory responses via the Fps-SHP-2 pathway.	PTPN11 HLA-A HLA-E	5.47e-07	11	53	3	22522491
Pubmed	Multiplexed kinase interactome profiling quantifies cellular network activity and plasticity.	CUL1 PTK2B DST HLA-A MAP1B BTK INSR CHD1 CFAP97 SFN	1.01e-06	910	53	10	36736316
Pubmed	Alternative peptide repertoire of HLA-E reveals a binding motif that is strikingly similar to HLA-A2.	HLA-A HLA-E	2.28e-06	2	53	2	22898188
Pubmed	Acf7 (MACF) is an actin and microtubule linker protein whose expression predominates in neural, muscle, and lung development.	DST MACF1	2.28e-06	2	53	2	11002341
Pubmed	Microtubule stability, Golgi organization, and transport flux require dystonin-a2-MAP1B interaction.	DST MAP1B	2.28e-06	2	53	2	22412020
Pubmed	Insulin receptor kinase phosphorylates protein tyrosine phosphatase containing Src homology 2 regions and modulates its PTPase activity in vitro.	PTPN11 INSR	2.28e-06	2	53	2	8135823
Pubmed	The HLA-A2 restricted T cell epitope HCV core 35-44 stabilizes HLA-E expression and inhibits cytolysis mediated by natural killer cells.	HLA-A HLA-E	2.28e-06	2	53	2	15681828
Pubmed	SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells.	PTK2B PTPN11	2.28e-06	2	53	2	10880513
Pubmed	A defined commensal consortium elicits CD8 T cells and anti-cancer immunity.	HLA-A HLA-E IL1R1	3.18e-06	19	53	3	30675064
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	HSPA12A DST SEMA6D HLA-A INSR MACF1 AKAP8L	3.46e-06	421	53	7	36976175
Pubmed	Expression of the mouse Macf2 gene during inner ear development.	DST MACF1	6.83e-06	3	53	2	12399109
Pubmed	Adapter function of protein-tyrosine phosphatase 1D in insulin receptor/insulin receptor substrate-1 interaction.	PTPN11 INSR	6.83e-06	3	53	2	7493946
Pubmed	A polypeptide binding conformation of calreticulin is induced by heat shock, calcium depletion, or by deletion of the C-terminal acidic region.	HLA-A HLA-E	6.83e-06	3	53	2	15383281
Pubmed	Positive and negative regulation by SLP-76/ADAP and Pyk2 of chemokine-stimulated T-lymphocyte adhesion mediated by integrin α4β1.	PTK2B FYB1	6.83e-06	3	53	2	26202465
Pubmed	ROS fusion tyrosine kinase activates a SH2 domain-containing phosphatase-2/phosphatidylinositol 3-kinase/mammalian target of rapamycin signaling axis to form glioblastoma in mice.	PTPN11 ROS1	6.83e-06	3	53	2	16885344
Pubmed	Human CD8 T lymphocytes recognize Mycobacterium tuberculosis antigens presented by HLA-E during active tuberculosis and express type 2 cytokines.	HLA-A HLA-E	6.83e-06	3	53	2	25631937
Pubmed	Hyperproliferation, induction of c-Myc and 14-3-3sigma, but no cell fragility in keratin-10-null mice.	KRT10 SFN	6.83e-06	3	53	2	12077355
Pubmed	MAP1B and clathrin are novel interacting partners of the giant cyto-linker dystonin.	DST MAP1B	6.83e-06	3	53	2	21936565
Pubmed	A transgenic insertional inner ear mutation on mouse chromosome 1.	DST IL1R1	6.83e-06	3	53	2	10763993
Pubmed	LAF4 maps to mouse chromosome 1 and human chromosome 2q11.2-q12.	DST IL1R1	6.83e-06	3	53	2	8662235
Pubmed	[Analysis on HLA-E polymorphism in Guangdong Han population].	HLA-A HLA-E	6.83e-06	3	53	2	15631661
Pubmed	ROS1 Fusion Mediates Immunogenicity by Upregulation of PD-L1 After the Activation of ROS1-SHP2 Signaling Pathway in Non-Small Cell Lung Cancer.	PTPN11 ROS1	6.83e-06	3	53	2	33324391
Pubmed	SHPTP2 serves adapter protein linking between Janus kinase 2 and insulin receptor substrates.	PTPN11 INSR	6.83e-06	3	53	2	8912646
Pubmed	Insulin/IGF-1 controls epidermal morphogenesis via regulation of FoxO-mediated p63 inhibition.	KRT10 INSR SFN	7.51e-06	25	53	3	23906066
Pubmed	The protein tyrosine kinase family of the human genome.	PTK2B BTK INSR ROS1	8.08e-06	83	53	4	11114734
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	PTK2B HSPA12A KRT10 VWF DST MAP1B EIF4B MACF1 CHD3 ARHGAP39 FGG	8.54e-06	1431	53	11	37142655
Pubmed	14-3-3sigma controls mitotic translation to facilitate cytokinesis.	KRT10 MAP1B EIF4B SFN	9.30e-06	86	53	4	17361185
Pubmed	A human skeletal muscle interactome centered on proteins involved in muscular dystrophies: LGMD interactome.	KRT10 PTPN11 VWF DST EIF4B HLA-E MACF1	1.02e-05	497	53	7	23414517
Pubmed	BioID-based intact cell interactome of the Kv1.3 potassium channel identifies a Kv1.3-STAT3-p53 cellular signaling pathway.	PTPN11 DST HLA-A MAP1B EIF4B MACF1 ARHGAP39 CRYBG3	1.12e-05	708	53	8	39231216
Pubmed	Profiling of tyrosine phosphorylation pathways in human cells using mass spectrometry.	PTK2B PTPN11 CHD1	1.32e-05	30	53	3	12522270
Pubmed	Assignment of the human helix-loop-helix transcription factor gene musculin/activated B-cell factor-1 (MSC) to chromosome 8q21 and its mouse homologue (Msc) to the proximal region of chromosome 1.	DST IL1R1	1.36e-05	4	53	2	10198176
Pubmed	Interaction of SH2-containing protein tyrosine phosphatase 2 with the insulin receptor and the insulin-like growth factor-I receptor: studies of the domains involved using the yeast two-hybrid system.	PTPN11 INSR	1.36e-05	4	53	2	8895367
Pubmed	Impaired platelet aggregation and sustained bleeding in mice lacking the fibrinogen motif bound by integrin alpha IIb beta 3.	VWF FGG	1.36e-05	4	53	2	8918453
Pubmed	Characterization of the CHD family of proteins.	CHD1 CHD3	1.36e-05	4	53	2	9326634
Pubmed	Glycoproteins VI and Ib-IX-V stimulate tyrosine phosphorylation of tyrosine kinase Syk and phospholipase Cgamma2 at distinct sites.	VWF BTK	1.36e-05	4	53	2	14656219
Pubmed	Relative expression levels of the HLA class-I proteins in normal and HIV-infected cells.	HLA-A HLA-E	1.36e-05	4	53	2	25754738
Pubmed	Cloning and characterization of mouse ACF7, a novel member of the dystonin subfamily of actin binding proteins.	DST MACF1	1.36e-05	4	53	2	8954775
Pubmed	Characterization of the mouse JAB1 cDNA and protein.	DST IL1R1	1.36e-05	4	53	2	10721695
Pubmed	Potential involvement of FRS2 in insulin signaling.	PTPN11 INSR	1.36e-05	4	53	2	10650943
Pubmed	Determination of Gab1 (Grb2-associated binder-1) interaction with insulin receptor-signaling molecules.	PTPN11 INSR	1.36e-05	4	53	2	9658397
Pubmed	ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.	VWF FYB1	1.36e-05	4	53	2	17003372
Pubmed	Optimized fragmentation schemes and data analysis strategies for proteome-wide cross-link identification.	CUL1 DST EIF4B MACF1 CHD1 CHD3 SFN	1.70e-05	538	53	7	28524877
Pubmed	Association of the insulin receptor with phospholipase C-gamma (PLCgamma) in 3T3-L1 adipocytes suggests a role for PLCgamma in metabolic signaling by insulin.	PTPN11 INSR	2.27e-05	5	53	2	9593725
Pubmed	Genetic risk for restenosis after coronary stenting.	INSR ROS1	2.27e-05	5	53	2	17275003
Pubmed	The ubiquitin E3 ligase SCF-FBXO24 recognizes deacetylated nucleoside diphosphate kinase A to enhance its degradation.	CUL1 KAT2A	2.27e-05	5	53	2	25582197
Pubmed	SHPS-1 is a scaffold for assembling distinct adhesion-regulated multi-protein complexes in macrophages.	PTK2B FYB1	2.27e-05	5	53	2	10469599
Pubmed	Fibrinogen stabilizes placental-maternal attachment during embryonic development in the mouse.	VWF FGG	2.27e-05	5	53	2	11891199
Pubmed	Beta-chemokine receptor CCR5 signals through SHP1, SHP2, and Syk.	PTK2B PTPN11	2.27e-05	5	53	2	10747947
Pubmed	Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases.	PTK2B INSR	2.27e-05	5	53	2	7529876
Pubmed	Negative regulation of Ros receptor tyrosine kinase signaling. An epithelial function of the SH2 domain protein tyrosine phosphatase SHP-1.	PTPN11 ROS1	2.27e-05	5	53	2	11266449
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	KRT10 PTPN11 MAP1B EIF4B HLA-E PCMTD1 SFN	2.30e-05	564	53	7	21565611
Pubmed	Integrative predictive model of coronary artery calcification in atherosclerosis.	VWF INSR KCNK2 FGG IL1R1	2.63e-05	229	53	5	19948975
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	DST FAT3 KRI1 MACF1 DNAH5	2.91e-05	234	53	5	36243803
Pubmed	Fibrinogen is required for maintenance of platelet intracellular and cell-surface P-selectin expression.	VWF FGG	3.40e-05	6	53	2	19332769
Pubmed	Distinct trafficking pathways mediate Nef-induced and clathrin-dependent major histocompatibility complex class I down-regulation.	HLA-A HLA-E	3.40e-05	6	53	2	10982373
Pubmed	Effect of the V3 loop deletion of envelope glycoprotein on cellular responses and protection against challenge with recombinant vaccinia virus expressing gp160 of primary human immunodeficiency virus type 1 isolates.	HLA-A HLA-E	3.40e-05	6	53	2	11932387
Pubmed	Molecular analysis of presentation by HLA-A2.1 of a promiscuously binding V3 loop peptide from the HIV-envelope protein to human cytotoxic T lymphocytes.	HLA-A HLA-E	3.40e-05	6	53	2	8671651
Pubmed	The dileucine-based sorting motif in HIV-1 Nef is not required for down-regulation of class I MHC.	HLA-A HLA-E	3.40e-05	6	53	2	10366557
Pubmed	The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes.	HLA-A HLA-E	3.40e-05	6	53	2	9582271
Pubmed	Enhanced HIV infectivity and changes in GP120 conformation associated with viral incorporation of human leucocyte antigen class I molecules.	HLA-A HLA-E	3.40e-05	6	53	2	10546855
Pubmed	Bruton tyrosine kinase is essential for botrocetin/VWF-induced signaling and GPIb-dependent thrombus formation in vivo.	VWF BTK	3.40e-05	6	53	2	16788103
Pubmed	Molecular alterations of the Fyn-complex occur as late events of human T cell activation.	PTK2B FYB1	3.40e-05	6	53	2	10229084
Pubmed	Sequential cleavage by metallopeptidases and proteasomes is involved in processing HIV-1 ENV epitope for endogenous MHC class I antigen presentation.	HLA-A HLA-E	3.40e-05	6	53	2	10799863
Pubmed	The cationic region from HIV tat enhances the cell-surface expression of epitope/MHC class I complexes.	HLA-A HLA-E	3.40e-05	6	53	2	14595379
Pubmed	HIV immune evasion disruption of antigen presentation by the HIV Nef protein.	HLA-A HLA-E	3.40e-05	6	53	2	21762823
Pubmed	The immunosuppressive peptide of HIV-1 gp41 like human type I interferons up-regulates MHC class I expression on H9 and U937 cells.	HLA-A HLA-E	3.40e-05	6	53	2	9373217
Pubmed	Nef-mediated MHC class I down-regulation unmasks clonal differences in virus suppression by SIV-specific CD8(+) T cells independent of IFN-gamma and CD107a responses.	HLA-A HLA-E	3.40e-05	6	53	2	19555986
Pubmed	Degenerate MHC restriction reveals the contribution of class I MHC molecules in determining the fine specificity of CTL recognition of an immunodominant determinant of HIV-1 gp160 V3 loop.	HLA-A HLA-E	3.40e-05	6	53	2	9120272
Pubmed	CoA Synthase is phosphorylated on tyrosines in mammalian cells, interacts with and is dephosphorylated by Shp2PTP.	PTPN11 BTK	3.40e-05	6	53	2	19763791
Pubmed	On the role of the second coding exon of the HIV-1 Tat protein in virus replication and MHC class I downregulation.	HLA-A HLA-E	3.40e-05	6	53	2	9840288
Pubmed	A single amino acid interchange yields reciprocal CTL specificities for HIV-1 gp160.	HLA-A HLA-E	3.40e-05	6	53	2	2789433
Pubmed	Spatial and functional relationship of GGAs and AP-1 in Drosophila and HeLa cells.	HLA-A HLA-E	3.40e-05	6	53	2	19847956
Pubmed	Repression of MHC class I gene promoter activity by two-exon Tat of HIV.	HLA-A HLA-E	3.40e-05	6	53	2	8493575
Pubmed	Minor contribution of HLA class I-associated selective pressure to the variability of HIV-1 accessory protein Vpu.	HLA-A HLA-E	3.40e-05	6	53	2	22503975
Pubmed	Three regions of HIV-1 gp160 contain clusters of immunodominant CTL epitopes.	HLA-A HLA-E	3.40e-05	6	53	2	8877415
Pubmed	Endocytosis of major histocompatibility complex class I molecules is induced by the HIV-1 Nef protein.	HLA-A HLA-E	3.40e-05	6	53	2	8612235
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	PTK2B DST MAP1B EIF4B MACF1 CRYBG3 CFAP97 SFN	4.52e-05	861	53	8	36931259
Pubmed	Generation of a functional cDNA encoding the LdH2 class-I molecule by using a single-LTR retroviral shuttle vector.	HLA-A HLA-E	4.76e-05	7	53	2	1705528
Pubmed	Further studies on polymorphic expression of GM1 and GD1a in mouse liver. The presence of a third allele on the Ggm-1 locus.	HLA-A HLA-E	4.76e-05	7	53	2	2808323
Pubmed	Nef interacts with the mu subunit of clathrin adaptor complexes and reveals a cryptic sorting signal in MHC I molecules.	HLA-A HLA-E	4.76e-05	7	53	2	9586638
Pubmed	CD8+ T-cell expansion and maintenance after recombinant adenovirus immunization rely upon cooperation between hematopoietic and nonhematopoietic antigen-presenting cells.	HLA-A HLA-E	4.76e-05	7	53	2	21088134
Pubmed	The Tla locus: a new allele and antigenic specificity.	HLA-A HLA-E	4.76e-05	7	53	2	69663
Pubmed	Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense.	HLA-A HLA-E	4.76e-05	7	53	2	12459592
Pubmed	Multiple sequences related to classical histocompatibility antigens in the mouse genome.	HLA-A HLA-E	4.76e-05	7	53	2	6264319
Pubmed	Sequence analysis of the C3H H-2K1k gene: relationship to the H-2 loci.	HLA-A HLA-E	4.76e-05	7	53	2	2714856
Pubmed	Class I MHC molecules on hematopoietic cells can support intrathymic positive selection of T cell receptor transgenic T cells.	HLA-A HLA-E	4.76e-05	7	53	2	10500200
Pubmed	Structural analysis of H-2Kf and H-2Kfm1 by using H-2K locus-specific sequences.	HLA-A HLA-E	4.76e-05	7	53	2	2391419
Pubmed	Embryonic mouse STO cell-derived xenografts express hepatocytic functions in the livers of nonimmunosuppressed adult rats.	HLA-A HLA-E	4.76e-05	7	53	2	15671142
Pubmed	GENETIC BASIS OF SUSCEPTIBILITY TO VIRAL LEUKAEMOGENESIS.	HLA-A HLA-E	4.76e-05	7	53	2	14215561
Pubmed	A saturation hypothesis to explain both enhanced and impaired learning with enhanced plasticity.	HLA-A HLA-E	4.76e-05	7	53	2	28234229
Pubmed	Interaction of H-2Db with mutant histocompatibility gene H (KH-11) in the mouse.	HLA-A HLA-E	4.76e-05	7	53	2	6242891
Pubmed	Characterization of a severe parenchymal phenotype of experimental autoimmune encephalomyelitis in (C57BL6xB10.PL)F1 mice.	HLA-A HLA-E	4.76e-05	7	53	2	17512611
Pubmed	Amino acid sequence of residues 1-98 of the K-2Kb murine major histocompatibility alloantigen: comparison with H-2Kb and H-2db reveals extensive localized differences.	HLA-A HLA-E	4.76e-05	7	53	2	7018573
Pubmed	Induction of the H-2 D antigen during B cell activation.	HLA-A HLA-E	4.76e-05	7	53	2	2642506
Pubmed	A complex major histocompatibility complex D locus variant generated by an unusual recombination mechanism in mice.	HLA-A HLA-E	4.76e-05	7	53	2	9037062
Pubmed	Simultaneous assessment of CD4 and MHC-I downregulation by Nef primary isolates in the context of infection.	HLA-A HLA-E	4.76e-05	7	53	2	19643141
Interaction	CBL interactions	PTK2B KRT10 PTPN11 HLA-A BTK INSR PCMTD1 FYB1 SFN	5.15e-06	516	51	9	int:CBL
Interaction	RYK interactions	PTPN11 DST HLA-A FAT3 INSR SDK1	1.53e-05	212	51	6	int:RYK
Cytoband	17q21	KRT10 KAT2A	2.44e-03	63	53	2	17q21
GeneFamily	EF-hand domain containing\|Plakins	DST MACF1	1.46e-04	8	42	2	939
GeneFamily	PHD finger proteins\|NuRD complex	CHD5 CHD3	3.43e-04	12	42	2	1305
GeneFamily	Receptor Tyrosine Kinases\|CD molecules	INSR ROS1	3.89e-03	40	42	2	321
GeneFamily	C1-set domain containing	HLA-A HLA-E	4.28e-03	42	42	2	591
GeneFamily	Histocompatibility complex\|C1-set domain containing	HLA-A HLA-E	4.68e-03	44	42	2	588
GeneFamily	Fibronectin type III domain containing	INSR ROS1 SDK1	6.06e-03	160	42	3	555
Coexpression	ACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP	KRT10 SEMA6D FAT3 KCNK2 FYB1	9.13e-06	139	53	5	M6754
Coexpression	FAN_EMBRYONIC_CTX_ASTROCYTE_2	DST SEMA6D FIBIN FAT3 MACF1	1.50e-05	154	53	5	M39034
Coexpression	GSE40493_BCL6_KO_VS_WT_TREG_UP	CUL1 PTK2B PTPN11 EIF4B PCMTD1	2.93e-05	177	53	5	M9401
Coexpression	TABULA_MURIS_SENIS_MAMMARY_GLAND_BASAL_CELL_AGEING	DST HLA-A MAP1B HLA-E FGG SFN	4.63e-05	322	53	6	MM3786
Coexpression	SMID_BREAST_CANCER_NORMAL_LIKE_UP	DST P3H2 BTK KRI1 IL1R1 FYB1 LILRA4	5.25e-05	485	53	7	M8513
Coexpression	DER_IFN_BETA_RESPONSE_UP	PTPN11 HLA-A MAP1B HLA-E	5.68e-05	103	53	4	M13453
Coexpression	BLANCO_MELO_MERS_COV_INFECTION_MCR5_CELLS_DN	HLA-A FIBIN DNAJC12	5.78e-05	37	53	3	M34003
Coexpression	TABULA_MURIS_SENIS_KIDNEY_KIDNEY_CORTEX_ARTERY_CELL_AGEING	HLA-A INSR HLA-E	6.78e-05	39	53	3	MM3725
Coexpression	HU_GENOTOXIC_DAMAGE_4HR	CUL1 HLA-A HLA-E	9.10e-05	43	53	3	MM1204
Coexpression	ABBUD_LIF_SIGNALING_1_UP	VWF FGG IL1R1	9.10e-05	43	53	3	M1458
Coexpression	ABBUD_LIF_SIGNALING_1_UP	VWF FGG IL1R1	1.04e-04	45	53	3	MM636
Coexpression	AIZARANI_LIVER_C32_MVECS_3	VWF HLA-A HLA-E IL1R1	1.20e-04	125	53	4	M39131
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	SEMA6D EIF4B KRI1 KAT2A IL1R1 D2HGDH CFAP97 SFN	1.55e-04	776	53	8	M1107
Coexpression	BUSSLINGER_GASTRIC_IMMUNE_CELLS	PTK2B PTPN11 CSGALNACT2 HLA-A EIF4B HLA-E KRI1 MACF1 CHD1 CHD3 FYB1	1.63e-04	1492	53	11	M40023
Coexpression	HUPER_BREAST_BASAL_VS_LUMINAL_UP	DST P3H2 SFN	1.70e-04	53	53	3	M13422
Coexpression	GRAESSMANN_RESPONSE_TO_MC_AND_DOXORUBICIN_DN	SEMA6D EIF4B KRI1 KAT2A IL1R1 D2HGDH CFAP97 SFN	1.82e-04	794	53	8	MM982
Coexpression	GSE9946_IMMATURE_VS_LISTERIA_INF_MATURE_DC_UP	GPATCH3 KCNK2 PRKG2 SDK1	1.86e-04	140	53	4	M418
Coexpression	GAO_LARGE_INTESTINE_ADULT_CG_GOBLET_CELL_SUBTYPE_2	VWF FYB1 DNAH5	2.11e-04	57	53	3	M39164
Coexpression	TABULA_MURIS_SENIS_BRAIN_NON_MYELOID_INTERNEURON_AGEING	HLA-A MAP1B HLA-E	2.34e-04	59	53	3	MM3688
ToppCell	ILEUM-non-inflamed-(9)_Enteric_neurons\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HSPA12A DST SEMA6D MAP1B FIBIN P3H2	1.23e-07	196	53	6	998aa523555ed6bc9c1b5cacbf7ba77c7b218e6b
ToppCell	ILEUM-non-inflamed-(9)_Neuro_cell\|non-inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	HSPA12A DST SEMA6D MAP1B FIBIN P3H2	1.23e-07	196	53	6	2b08cd6730119d5dea0152709ab8de580b66cd3c
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK2B HSPA12A CHD5 CHD3 FYB1	1.14e-06	155	53	5	72a19a9ecfd13f6769c4b447d3ce01a855ec6ec7
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l25\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF GLS2 MAP1B KCNK2 IL1R1	2.58e-06	183	53	5	6f8f997ffc9eaebca2683de125b6069d07c07d26
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ROS1 DNAH5 PKHD1L1 SDK1	2.65e-06	184	53	5	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF DST GLS2 MAP1B KCNK2	2.65e-06	184	53	5	f506d0ee48f39d6f59f19554217dfdf0987cc405
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF DST GLS2 MAP1B KCNK2	2.65e-06	184	53	5	8bcb1c4bc8ffef74338cdade926a94711de93c64
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ROS1 DNAH5 PKHD1L1 SDK1	2.65e-06	184	53	5	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FAT3 ROS1 DNAH5 PKHD1L1 SDK1	2.65e-06	184	53	5	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-neuron\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK2B HSPA12A MAP1B CHD5 CHD3	2.87e-06	187	53	5	e04a84989d624378141042768383b9c846901f2d
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal-nan\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK2B HSPA12A MAP1B CHD5 CHD3	2.87e-06	187	53	5	24cc03c748e15f7ef0e6509ca5a6ca583fb9c573
ToppCell	facs-Brain_Non-Myeloid-Hippocampus-24m-Neuronal\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK2B HSPA12A MAP1B CHD5 CHD3	2.87e-06	187	53	5	2f153b203fe79f206319603cf94d3a03ab49a05d
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MAP1B CHD5 PRKG2 IL1R1	2.95e-06	188	53	5	a91443aa8fa8fa87f7501c59219daa0305bd0bbf
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST P3H2 FYB1 DNAH5 SDK1	3.02e-06	189	53	5	aadb7a2de4cbe7f0958651f2739bba430b93f5c1
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	DST P3H2 FYB1 DNAH5 SDK1	3.02e-06	189	53	5	8977f3295b7df7c7474b3f371de90a82ae4bb50c
ToppCell	IPF-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	PTK2B CSGALNACT2 INSR CHD1 FYB1	3.10e-06	190	53	5	f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCell	10x3'2.3-week_12-13-Mesenchymal_osteo-stroma-osteoblast_precursor\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	SEMA6D MAP1B FAT3 KCNK2 CDH15	3.18e-06	191	53	5	98b907f8fa024cf32e462323b782c5a371327bbd
ToppCell	COVID-19-Heart-EC_(POSTN)\|Heart / Disease (COVID-19 only), tissue and cell type	VWF HLA-A HLA-E IL1R1 PKHD1L1	3.26e-06	192	53	5	c0c34785a7bdf461722029b322e9184e3d9b3c26
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature-Adult_Glia\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPA12A DST SEMA6D FIBIN P3H2	3.43e-06	194	53	5	d429bb5e422a07bd92f0dc48cd51528e8b7d9a72
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPA12A DST SEMA6D FIBIN P3H2	3.43e-06	194	53	5	bffdf6db0bf3fb338e7bb0789ae7dcde1fce0094
ToppCell	3'-Pediatric_IBD-SmallIntestine-Neuronal-Glial_mature\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HSPA12A DST SEMA6D FIBIN P3H2	3.43e-06	194	53	5	408dfc7060095972a54ae37ae8105521df6fbbee
ToppCell	10x_3'_v2v3-Neoplastic-Differentiated-like-MES-like-MES-like_hypoxia_independent-F\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	DST SEMA6D MAP1B KAT2A CDH15	3.61e-06	196	53	5	b8b9801181d7604871b48aebacb295d0a57a5eaf
ToppCell	kidney_cells-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Afferent_/_Efferent_Arteriole_Endothelial_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	VWF DST MAP1B HLA-E CRYBG3	3.89e-06	199	53	5	9b02acae6325b0ac9642438a4431285ff396e5fe
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo-stroma\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SEMA6D MAP1B FIBIN FAT3 CDH15	3.98e-06	200	53	5	3c898e81444b001835c3f1bbc68183078701b135
ToppCell	10x5'v1-week_17-19-Mesenchymal_osteo\|week_17-19 / cell types per 3 fetal stages;per 3',per 5'	SEMA6D MAP1B FIBIN FAT3 CDH15	3.98e-06	200	53	5	3eca8ffeb41b664fbdbbd70b375c5d953503ab29
ToppCell	COVID-19-lung-Mesothelial\|lung / Disease (COVID-19 only), tissue and cell type	HSPA12A SEMA6D MAP1B PKHD1L1	3.57e-05	156	53	4	e1f563869b3bf997eaa2e756e31b53db1a478903
ToppCell	3'_v3-blood-Lymphocytic_Invariant-Inducer-like-ILC3\|blood / Manually curated celltypes from each tissue	DST FAT3 CHD5 IL1R1	3.66e-05	157	53	4	eb2520c237543ea4869d4386afc0457b111f6193
ToppCell	P07-Mesenchymal-developing_mesenchymal_cell-mesenchymal_immature_unknown_1\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	FIBIN FAT3 MACF1 PRKG2	4.03e-05	161	53	4	b19f82dd98a3064581793711bb70373f18abecd9
ToppCell	Bac-SEP-Myeloid-tDC\|Bac-SEP / Disease, Lineage and Cell Type	DNAJC12 KAT2A CRYBG3 LILRA4	4.44e-05	165	53	4	8728f927502e56f2768b4224e9111939d3d7815a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLS2 FAT3 INSR SDK1	4.55e-05	166	53	4	60060b03f2abfa3cc08107ab5a9f578e60e4ae16
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLS2 FAT3 INSR SDK1	4.55e-05	166	53	4	ec9161d388db5a257b8d125c14f9dd911d5d5d4a
ToppCell	5'-Parenchyma_lung-Epithelial-Epithelial_transtional-secretory-tracheobronchial_goblet_cell-Goblet_(subsegmental)-\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	GLS2 FAT3 INSR SDK1	4.55e-05	166	53	4	4586d6725403f879fc96f67be579022587ce1906
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Granulocytic-Neutrophil\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	HLA-A HLA-E LIPK FYB1	4.55e-05	166	53	4	6a65dff1333f39ec8c584e6df04b8c1e7f1c8946
ToppCell	COVID-19-Heart-Neuronal\|COVID-19 / Disease (COVID-19 only), tissue and cell type	HSPA12A DST SEMA6D MAP1B	4.76e-05	168	53	4	88c2c574f428c2502b5fe099bd73b0758f668ef6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SEMA6D FIBIN P3H2 ROS1	4.99e-05	170	53	4	3174ea9cf93892a8b41de10fd4ff6f06bb41502d
ToppCell	E16.5-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_mature\|E16.5 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PTK2B VWF DST SDK1	5.22e-05	172	53	4	9a1743abcd5fbd38253ea84d88ad716cfb71de36
ToppCell	normal_Lymph_Node-Myeloid_cells-pDCs\|Myeloid_cells / Location, Cell class and cell subclass	DST KRI1 KAT2A LILRA4	5.46e-05	174	53	4	2274648b80dd74f3c948a779bba3391095964c34
ToppCell	facs-Brain_Myeloid-Cerebellum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST FAT3 MACF1 FGG	5.58e-05	175	53	4	1ea6cf9da26601646f57fa14d558a5e9e1f0b345
ToppCell	B_cells-pDCs\|B_cells / Immune cells in Kidney/Urine in Lupus Nephritis	DST P3H2 FYB1 LILRA4	5.71e-05	176	53	4	ce757de9e09a225f3f96433f103f43619b0e0dda
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-E MACF1 FYB1 CFAP97	5.83e-05	177	53	4	d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	HLA-E MACF1 FYB1 CFAP97	5.83e-05	177	53	4	f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCell	Adult-Epithelial-club_cell-D175\|Adult / Lineage, Cell type, age group and donor	INSR KCNK2 IL1R1 DNAH5	5.83e-05	177	53	4	d652b7d84fe6aa38319d8d5adc72c70441bd0088
ToppCell	CV-Severe-7\|Severe / Virus stimulation, Condition and Cluster	DST HLA-A HLA-E TMX3	5.83e-05	177	53	4	82fdd6185b368f54f03de389427cbe3071d21a99
ToppCell	COVID-19_Mild-Lymphoid_T/NK-NK_activated\|COVID-19_Mild / Disease group, lineage and cell class	HLA-E MACF1 FYB1 CFAP97	5.83e-05	177	53	4	6978a22fef40c8b455342373abe7593f5ede0fa4
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated\|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)	HLA-E MACF1 FYB1 CFAP97	5.83e-05	177	53	4	936ab2b180a052387124f68d0c7f41c0b164e748
ToppCell	PBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	HLA-E MACF1 FYB1 CFAP97	5.83e-05	177	53	4	d5aeda113afaa2425874394610344570c9078478
ToppCell	droplet-Kidney-nan-18m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAP1B KCNK2 LIPK SFN	5.96e-05	178	53	4	445fb243d738a34794d66f34b92dde1f3ea6738e
ToppCell	10x3'2.3-week_12-13-Mesenchymal_myocytic-stroma-muscle_stem_cell\|week_12-13 / cell types per 3 fetal stages;per 3',per 5'	MAP1B FAT3 SDK1 CDH15	5.96e-05	178	53	4	8f31b3fac51591f7f2bcb898c07708b3e9f93a16
ToppCell	normal-na-Lymphocytic_T-CD4-positive,_alpha-beta_T_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	EIF4B HLA-E CHD3 FYB1	5.96e-05	178	53	4	fa3585383a1e7da460c88a802aaa81246d681b6b
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_2\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTK2B SEMA6D FAT3 ROS1	6.09e-05	179	53	4	8766a5a066091879f521acfc612abf563ff78808
ToppCell	droplet-Bladder-BLADDER-1m-Epithelial-endothelial_cell\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A FIBIN FAT3 CHD5	6.09e-05	179	53	4	c7c74e26bbf86c5326ee38bac7de111d5414f46b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_3-Exc_L3_RORB_CARTPT\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	PTK2B ROS1 PRKG2 CRYBG3	6.23e-05	180	53	4	5e78b29fa1cbdcf502fee3577e5b45766b90d1dc
ToppCell	Control-Epithelial_cells-Airway_club\|Control / group, cell type (main and fine annotations)	ROS1 IL1R1 DNAH5 SDK1	6.36e-05	181	53	4	c755d23dd9aabc717dc73e2b3fa99a1f751e6507
ToppCell	facs-Lung-nan-3m-Endothelial-Artery_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	VWF DST MAP1B PKHD1L1	6.64e-05	183	53	4	12e876d6205af8aad74265c668b5e95b9e7487f3
ToppCell	COVID-19_Mild-NK_activated\|COVID-19_Mild / Disease condition and Cell class	HLA-E MACF1 FYB1 CFAP97	6.64e-05	183	53	4	22bd05135906d0ecc4ba8c2e0a666093d1bf3b8f
ToppCell	IPF-Epithelial-ATII\|IPF / Disease state, Lineage and Cell class	P3H2 ROS1 FGG SFN	6.92e-05	185	53	4	563b4e6d92bb5d77a3829556116a8e99aebac615
ToppCell	IPF-Epithelial-ATII\|World / Disease state, Lineage and Cell class	P3H2 ROS1 FGG SFN	7.07e-05	186	53	4	6a4ff2da0af0f5e590d9f9daa5b5e9ac8c868947
ToppCell	droplet-Lung-nan-21m-Myeloid-Alveolar_Macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A DST CHD5 ARHGAP39	7.07e-05	186	53	4	f1aa0c58336d23bcbe52a59e7af954d20085bdb6
ToppCell	PCW_07-8.5-Hematologic_ErythroMegGranulo\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	PTK2B BTK FYB1 PKHD1L1	7.07e-05	186	53	4	294839944266407c40ef86e1d3e0fce4652b70ff
ToppCell	343B-Endothelial_cells-Endothelial-E-\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF HLA-A INSR HLA-E	7.07e-05	186	53	4	dae6a98963c78bf7518ebab8dc02f173c3b0f7f7
ToppCell	droplet-Lung-nan-21m-Myeloid-alveolar_macrophage\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HSPA12A DST CHD5 ARHGAP39	7.07e-05	186	53	4	8f77e552e613b6e124443c7f6ef5c1316a5ff8db
ToppCell	343B-Endothelial_cells-Endothelial-E\|Endothelial_cells / Donor, Lineage, Cell class and subclass (all cells)	VWF HLA-A INSR HLA-E	7.07e-05	186	53	4	080e56113b89138277a2bd2eabddfa6cd1a18b61
ToppCell	facs-Brain_Non-Myeloid-Cortex-24m\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PTK2B HSPA12A CHD5 CHD3	7.07e-05	186	53	4	7278a1a1bf9bb27aeb03852134defb31b62f30d6
ToppCell	LV-10._Endothelium_II\|World / Chamber and Cluster_Paper	VWF HLA-E IL1R1 PKHD1L1	7.22e-05	187	53	4	7876dcb4800c2e54874df3d933efb79307a64a97
ToppCell	COVID-19-kidney-Fibroblast-1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MAP1B INSR IL1R1 SDK1	7.22e-05	187	53	4	76bfe8c42430a230a8bdf299575c444fb7780f24
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF DST MAP1B PKHD1L1	7.22e-05	187	53	4	12129e02638c20d9b7c1c6e512d48bfd966e1029
ToppCell	Control-Fibroblasts-Alveolar_FB\|Control / group, cell type (main and fine annotations)	DST FAT3 MACF1 SDK1	7.22e-05	187	53	4	92d468dde81125d51daf7abd4703741abe1ab91c
ToppCell	Smart-seq2-lymph_node_(Smart-seq2)-lymphocytic-T_lymphocytic-effector_CD4-positive,_alpha-beta_T_cell\|lymph_node_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HLA-A CHD1 CHD3 FYB1	7.22e-05	187	53	4	e61c1755531469dd3850c9740474b5ad4e0499c1
ToppCell	droplet-Lung-18m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	VWF DST MAP1B PKHD1L1	7.22e-05	187	53	4	83930ef55191eff9006113feaeabb3c2fa21fd05
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	P3H2 FAT3 MACF1 SDK1	7.37e-05	188	53	4	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	COPD-Epithelial-ATII\|COPD / Disease state, Lineage and Cell class	P3H2 ROS1 FGG SFN	7.37e-05	188	53	4	eb6d79d733b53f64ca615bb777c64ed456866549
ToppCell	P28-Endothelial-large_vessel_endothelial_cell\|P28 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PTK2B VWF DST MAP1B	7.37e-05	188	53	4	263169029293e005bcffd87db20221fdd2d3917e
ToppCell	Smart-seq2-spleen_(Smart-seq2)\|Smart-seq2 / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	HLA-A HLA-E CHD1 LILRA4	7.52e-05	189	53	4	b0244a9d1b5c8ad4708750b691184f3491b13900
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	P3H2 FAT3 MACF1 SDK1	7.52e-05	189	53	4	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	COPD-Myeloid-ncMonocyte\|World / Disease state, Lineage and Cell class	PTK2B CSGALNACT2 INSR CHD1	7.68e-05	190	53	4	aece860b5609ad5a8fc920d685f0d0ec71bf9018
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	DST FAT3 MACF1 CRYBG3	7.68e-05	190	53	4	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	droplet-Mammary_Gland-nan-18m-Epithelial-nan\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MAP1B FGG SFN	7.68e-05	190	53	4	313ad9ec736e3da5968dc9e9bbdfe508d935b552
ToppCell	facs-Pancreas-Endocrine-24m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MAP1B PRKG2 IL1R1	7.83e-05	191	53	4	3387b95a3f2445c672d407922fdce3a91eabaef8
ToppCell	(1)_Osterolineage_cells-(10)_OLC-1\|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis	SEMA6D FAT3 KCNK2 CDH15	7.83e-05	191	53	4	78ad7c555409ce1391bce406bc0f3ef575329ece
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2-AF1\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST FAT3 MACF1 SDK1	7.83e-05	191	53	4	6688cee34beee4f151ac17fccbc9c26a9aad72e1
ToppCell	COVID-19-kidney-Myeloid\|kidney / Disease (COVID-19 only), tissue and cell type	HLA-A HLA-E IL1R1 FYB1	7.99e-05	192	53	4	441cd1ec171f643b28e1f6f9c04def629cc7391b
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF HLA-A HLA-E PKHD1L1	7.99e-05	192	53	4	fa0ef05a32c661bdd59b5a9b6f75fd647ee937f3
ToppCell	nucseq-Mesenchymal-Fibroblastic-Fibroblastic_2\|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2	DST FAT3 MACF1 SDK1	7.99e-05	192	53	4	99ce9e3c4c50cf64ebb62145f2b5420efa0db309
ToppCell	5'-GW_trimst-1.5-SmallIntestine-Endothelial-lymphatic_endothelial-LEC4_(STAB2+)\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	VWF HLA-A HLA-E PKHD1L1	7.99e-05	192	53	4	4e63d95f75fe6eb3f817e84528883e95093c5bbd
ToppCell	facs-Mammary_Gland-Mammary_Gland-18m-Epithelial-basal_cell\|Mammary_Gland / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DST MAP1B FGG SFN	7.99e-05	192	53	4	c47df468cf78a90929913c9022e8078a53cdf680
ToppCell	RV-10._Endothelium_II\|RV / Chamber and Cluster_Paper	VWF HLA-E IL1R1 PKHD1L1	8.15e-05	193	53	4	01c2df9206f1527c578e808978e58196c35e72f5
ToppCell	COPD-Myeloid-ncMonocyte\|COPD / Disease state, Lineage and Cell class	PTK2B CSGALNACT2 INSR CHD1	8.15e-05	193	53	4	936ca95995599356b794fba32bfd82d8de339365
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST FAT3 MACF1 SDK1	8.15e-05	193	53	4	99525545552b371c86b18b6ea6f4897dc6e9a9ec
ToppCell	Children_(3_yrs)-Mesenchymal-matrix_fibroblast_1_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DST FAT3 MACF1 SDK1	8.15e-05	193	53	4	b3ad5ff480d99217f36cc7471e5a96a519ddb409
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-TAM-MG-TAM-MG_pro-infl_I-G\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	BTK HLA-E FYB1 LILRA4	8.15e-05	193	53	4	26a55e98005163122d277480d1d44dd6910ab42f
ToppCell	Mesenchymal-matrix_fibroblast_1_cell\|World / Lineage, Cell type, age group and donor	DST FAT3 IL1R1 SDK1	8.15e-05	193	53	4	acad568621ed677031797b8c2e34dafea798d681
ToppCell	Fetal_29-31_weeks-Mesenchymal-matrix_fibroblast_1_cell\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DST FAT3 IL1R1 SDK1	8.32e-05	194	53	4	011e14d9ed1393275f892060e7708ffadcd0767f
ToppCell	PCW_13-14-Mesenchymal-Mesenchymal_fibroblastic-mes_immature5_(6)\|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung	DST FAT3 MACF1 IL1R1	8.32e-05	194	53	4	b1bb0f846d2865efdd9bc8842b16b9d069785882
ToppCell	LV-10._Endothelium_II\|LV / Chamber and Cluster_Paper	VWF HLA-E IL1R1 PKHD1L1	8.32e-05	194	53	4	b6cc849fa08599bff9839ef382d190cc964e273e
ToppCell	21-Trachea-Mesenchymal-Mesenchyme_RSPO2+\|Trachea / Age, Tissue, Lineage and Cell class	DST FIBIN FAT3 CDH15	8.32e-05	194	53	4	8fc98d2c9d94f3bc6292265e20ab71c4f1f37bb3
ToppCell	368C-Fibroblasts-Fibroblast-G-\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DST FIBIN FAT3 MACF1	8.32e-05	194	53	4	d9eec28fa7b255c0ec023276dd955f1e276e7159
ToppCell	10x5'v1-week_14-16-Mesenchymal_osteo-stroma-osteoblast\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MAP1B FIBIN FAT3 CDH15	8.32e-05	194	53	4	292ce9021678534c9eedb367b9772a9d976208a8
ToppCell	10x5'-bone_marrow-Myeloid_Dendritic\|bone_marrow / Manually curated celltypes from each tissue	DST P3H2 CRYBG3 LILRA4	8.32e-05	194	53	4	768271ae45ff9f6aa3cd9b0ed15fa3caaa68a7b0
ToppCell	368C-Fibroblasts-Fibroblast-G\|Fibroblasts / Donor, Lineage, Cell class and subclass (all cells)	DST FIBIN FAT3 MACF1	8.32e-05	194	53	4	e4d7e9709ce42d4610e44d3445927eefbcbb9eff
ToppCell	Control-Epithelial-ATII\|Epithelial / Disease state, Lineage and Cell class	P3H2 MACF1 ROS1 IL1R1	8.32e-05	194	53	4	a01de094f7bfd099bcbb2f94224690a2efb887b4
Disease	Parapsoriasis en Plaques	HLA-A HLA-E	2.70e-06	2	49	2	C0162442
Disease	Erythroderma, Maculopapular	HLA-A HLA-E	2.70e-06	2	49	2	C0014799
Disease	Parakeratosis Variegata	HLA-A HLA-E	2.70e-06	2	49	2	C0030437
Disease	Parapsoriasis	HLA-A HLA-E	2.70e-06	2	49	2	C0030491
Disease	cardiovascular disease biomarker measurement, ankle brachial index	FAT3 DNAH5	2.69e-05	5	49	2	EFO_0003912, EFO_0005278
Disease	graft-versus-host disease (implicated_via_orthology)	HLA-A HLA-E	5.64e-05	7	49	2	DOID:0081267 (implicated_via_orthology)
Disease	susceptibility to Mycobacterium tuberculosis infection measurement	HLA-A HLA-E SDK1	4.00e-04	86	49	3	EFO_0008407
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	PTPN11 HLA-A INSR MACF1	5.07e-04	222	49	4	EFO_0008317, EFO_0020943
Disease	venous thromboembolism, plasminogen activator inhibitor 1 measurement	VWF FGG	5.56e-04	21	49	2	EFO_0004286, EFO_0004792
Disease	biological sex	SEMA6D FAT3 ARHGAP39 SDK1	5.79e-04	230	49	4	PATO_0000047
Disease	venous thromboembolism, tissue plasminogen activator measurement	VWF FGG	6.68e-04	23	49	2	EFO_0004286, EFO_0004791
Disease	Drug habituation	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0013170
Disease	Substance-Related Disorders	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0236969
Disease	Drug abuse	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0013146
Disease	Drug Use Disorders	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0013222
Disease	Drug Dependence	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C1510472
Disease	Substance Dependence	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0038580
Disease	Substance Use Disorders	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0038586
Disease	Organic Mental Disorders, Substance-Induced	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C0029231
Disease	Prescription Drug Abuse	HSPA12A SEMA6D INSR	9.32e-04	115	49	3	C4316881
Disease	Substance abuse problem	HSPA12A SEMA6D INSR	9.56e-04	116	49	3	C0740858
Disease	Drug-Induced Stevens Johnson Syndrome	CUL1 HLA-A	1.07e-03	29	49	2	C1274933
Disease	smoking status measurement, Cannabis use, schizophrenia	SEMA6D SDK1	1.07e-03	29	49	2	EFO_0006527, EFO_0007585, MONDO_0005090
Disease	Toxic Epidermal Necrolysis	CUL1 HLA-A	1.07e-03	29	49	2	C0014518
Disease	Mycoplasma-Induced Stevens-Johnson Syndrome	CUL1 HLA-A	1.07e-03	29	49	2	C3658301
Disease	Stevens-Johnson Syndrome Toxic Epidermal Necrolysis Spectrum	CUL1 HLA-A	1.07e-03	29	49	2	C3658302
Disease	factor XI measurement, venous thromboembolism	VWF FGG	1.14e-03	30	49	2	EFO_0004286, EFO_0004694
Disease	Stevens-Johnson Syndrome	CUL1 HLA-A	1.14e-03	30	49	2	C0038325
Disease	Squamous cell carcinoma	KRT10 PTPN11 SFN	1.16e-03	124	49	3	C0007137
Disease	Cleft palate, cleft lip	PTPN11 MAP1B EIF4B SDK1	1.19e-03	279	49	4	EFO_0003959, HP_0000175
Disease	Large cell carcinoma of lung	BTK ROS1	1.30e-03	32	49	2	C0345958
Disease	eosinophil percentage of leukocytes	PTK2B HLA-A CHD1 D2HGDH SFN SDR9C7	1.42e-03	746	49	6	EFO_0007991
Disease	factor VIII measurement, venous thromboembolism	VWF FGG	1.46e-03	34	49	2	EFO_0004286, EFO_0004630
Disease	glycine measurement	GLS2 INSR FGG	1.54e-03	137	49	3	EFO_0009767
Disease	Keloid	FGG SFN	1.55e-03	35	49	2	C0022548

Protein segments in the cluster

Peptide	Gene	Start	Entry
YTEKDYGTIYFGDLG	ANKRD30B	26	Q9BXX2
YYTDGEESSDDGKKY	CFAP97	131	Q9P2B7
EYEGYKYERIDGGIT	CHD5	1061	Q8TDI0
DSTCERLYYGDDEKY	C8A	191	P07357
YDKRRETDYSDKGYN	CRYBG3	1971	Q68DQ2
DYYRYLAEVATGDDK	SFN	126	P31947
KLSYYEYDFERGRRG	BTK	36	Q06187
NYRSEDTEDYYTLLG	DNAJC12	6	Q9UKB3
GTRKGDYFYAYDVDI	FAM187A	126	A6NFU0
EDDSNLLIGIYEYGY	CHD1	1256	O14646
ERDLYRSGYDYSELD	AKAP8L	136	Q9ULX6
GVFLEKDYEIYRDYS	ARHGAP39	176	Q9C0H5
SRYLGYIKDYEGATL	KAT2A	636	Q92830
LRGYEQFAYDGKDYL	HLA-E	131	P13747
GEPRDYSKYYKTIDD	KRT10	191	P13645
SDVGYIRYTLYKEGA	LILRA4	246	P59901
TRTSDVGGYYYEKIE	MAP1B	1896	P46821
DRDGDGYIDYYEFVA	DST	7246	Q03001
DYVAGGSDIEYLDFY	KCNK2	271	O95069
VYYDRDGGDKDARDS	GPATCH3	366	Q96I76
IDRGDYYLEGYRDNA	PCMTD1	36	Q96MG8
EEGKYGYVLRSYLAD	FYB1	751	O15117
GDKTFEEYLDEYYRL	KRI1	496	Q8N9T8
ETGDRNYAIGYYLKE	GLS2	316	Q9UI32
YGSLGVDYEFEKLLY	HSPA12A	346	O43301
TRDIYETDYYRKGGK	INSR	1181	P06213
DYYDLYGGEKFATLA	PTPN11	61	Q06124
EYLGYKAGLYEAIAD	P3H2	261	Q8IVL5
YYDKGDYIIREGEEG	PRKG2	306	Q13237
ADIFDRDGDGYIDYY	MACF1	7086	Q9UPN3
EADKYRLTYAYFAGG	FGG	296	P02679
GYYRTERDKGTQYEL	CSGALNACT2	221	Q8N6G5
RDSYGEDYFRIYTDK	SDR9C7	231	Q8NEX9
LLEDFLDYEGYKYER	CHD3	1091	Q12873
LDYEGYKYERIDGGI	CHD3	1096	Q12873
YLERVDGEKDTYSYL	CUL1	761	Q13616
STRELESDYYLGGYD	FAT3	4386	Q8TDW7
GYRQDAYDGKDYIAL	HLA-A	136	P04439
GDFGLSRYIEDEDYY	PTK2B	566	Q14289
SYDLDGEESYGKYLR	FIBIN	106	Q8TAL6
IYYRELEYEAGSGTE	SDK1	1616	Q7Z5N4
YDTALIYDYEGDGSV	CDH15	731	P55291
YKLFIYGRDDYVGED	IL1R1	421	P14778
EALSRDGYVYKYDLS	D2HGDH	391	Q8N465
DNIYRKYITYTGGEE	DNAH5	1376	Q8TE73
GDDSFGDKYRDRYDS	EIF4B	216	P23588
YKRLGVYFDEYSGES	RARS2	256	Q5T160
YIRGKSYEYECSEDG	ZNF610	196	Q8N9Z0
IYTADTDGGYIEERY	TMX3	396	Q96JJ7
ETEAGYYKLSGEAYG	VWF	121	P04275
GDFGLARDIYKNDYY	ROS1	2101	P08922
SDVYRFYIKGDDRYA	PKHD1L1	401	Q86WI1
RYYRLSTLEYDGEEI	SEMA6D	146	Q8NFY4
YEEYDVTTKDGYILG	LIPK	46	Q5VXJ0