Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
DomainLRRC37_N

LRRC37A LRRC37A2

4.37e-054512IPR032754
DomainLRRC37AB_C

LRRC37A LRRC37A2

4.37e-054512PF14914
DomainLRRC37AB_C

LRRC37A LRRC37A2

4.37e-054512IPR029423
DomainLRRC37

LRRC37A LRRC37A2

4.37e-054512PF15779
DomainLRRC37A/B-like

LRRC37A LRRC37A2

4.37e-054512IPR015753
Pubmed

Nuclear relocation of the nephrin and CD2AP-binding protein dendrin promotes apoptosis of podocytes.

NPHS1 DDN

2.46e-06255217537921
Pubmed

Primate segmental duplication creates novel promoters for the LRRC37 gene family within the 17q21.31 inversion polymorphism region.

LRRC37A LRRC37A2

1.47e-05455222419166
Pubmed

Evolutionary dynamism of the primate LRRC37 gene family.

LRRC37A LRRC37A2

1.10e-041055223064749
Pubmed

Nephrin is involved in podocyte maturation but not survival during glomerular development.

NPHS1 DDN

1.60e-041255218046313
Pubmed

Application of gene network analysis techniques identifies AXIN1/PDIA2 and endoglin haplotypes associated with bicuspid aortic valve.

CSF1R MYLK

2.90e-041655220098615
Pubmed

The role of Pax2 in mouse inner ear development.

JAG2 MYO15A

3.29e-041755215242798
Pubmed

Identification of motif-based interactions between SARS-CoV-2 protein domains and human peptide ligands pinpoint antiviral targets.

DYRK1B PPP1R3F RGS3 DNAH11

5.12e-0423355437704626
Pubmed

Endodermal Hedgehog signals modulate Notch pathway activity in the developing digestive tract mesenchyme.

JAG2 CHGA

5.56e-042255221750033
Pubmed

Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

LRRC37A ZFC3H1 LARGE1

6.26e-041055539628581
Pubmed

Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly.

SNW1 ATG4D

6.63e-042455233220177
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

JAG2 TRPM4 MOGS DERL1 C6orf47

8.64e-0446855531056421
Pubmed

Notch signaling in stomach epithelial stem cell homeostasis.

JAG2 CHGA

9.70e-042955221402740
Pubmed

Identification and characterization of SAP25, a novel component of the mSin3 corepressor complex.

TTLL12 SAP25

1.04e-033055216449650
Pubmed

Fibroblast growth factor 10 represses premature cell differentiation during establishment of the intestinal progenitor niche.

JAG2 CHGA

1.33e-033455220883684
CoexpressionAtlasMyeloid Cells, DC.8-4-11b+.MLN, CD45-APC CD11b-FITC CD11c-eFluor780 CD4-PE CD8a-eF, Lymph Node, avg-2

ZMYND15 SLCO5A1 CSF1R MYLK SPINT1 CCSER2 ZFC3H1 LARGE1

5.86e-06413518GSM538263_500
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B LRRC37A2 C6orf47 BTNL9

3.55e-0515055453de595376a9fc92491dfd58ff25938b0bf79903
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_B-B_cell|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B LRRC37A2 C6orf47 BTNL9

3.55e-05150554e4b40b3243ed26d0c46bf196ac06e148834e7ed2
ToppCellsaliva-Severe-critical_progression_d28-40-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c09-GZMK-FOS_l|Severe-critical_progression_d28-40 / Compartment, severity and other cell annotations on 10x 3' data (130k)

PCED1B LRRC37A CCSER2 CD70

4.45e-0515955403d77e7fee40262bf0942aab96b273f1c4f5d8e3
ToppCelldroplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

TICRR MOGS SPINT1 PPP1R3F

4.56e-051605548a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Myeloid / Donor, Lineage, Cell class and subclass (all cells)

SLCO5A1 LRRC37A LRRC37A2 R3HCC1

5.02e-051645541aff83fc73b4e41e6f0d4b04dbca153bcc7a3518
ToppCellBasal_cells-Donor_07|World / lung cells shred on cell class, cell subclass, sample id

JAG2 LARP6 DDN TMEM200B

5.26e-05166554aea2ae12e4746149ebc6da063ef694381c098f80
ToppCellfacs-Marrow-T-cells-3m-Hematologic-MPP_Fraction_B_+_C|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

JAG2 TTLL12 BTNL9 LACTBL1

5.77e-05170554d70aaa0f4e5034bb9f61b832b5f9123870936d3c
ToppCell367C-Myeloid-Monocyte-CD16+_Monocyte|Monocyte / Donor, Lineage, Cell class and subclass (all cells)

SLCO5A1 LRRC37A LRRC37A2 R3HCC1

6.04e-05172554fb8ab2576b5c38db63573a3bf46b8d9d634c4999
ToppCelldroplet-Lung-LUNG-1m-Myeloid-Ccr7+_Dendritic|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ZMYND15 SLCO5A1 VPS37C ZFC3H1

6.32e-051745547be0c6248e77f2d0260b852b01e17892f7828f1b
ToppCelldroplet-Lung-1m-Hematologic-myeloid-myeloid_dendritic_cell-Ccr7+_dendritic|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

ZMYND15 SLCO5A1 VPS37C ZFC3H1

6.46e-051755541b910c08d2bfbcc77431ee66103e63a11a9d39fe
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

6.75e-051775544d2cdb57b427a42085c5f9affa0967b15e84dec3
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

7.68e-05183554612d93df03252d4d2ccdce5a9bc162cfd9172a1a
ToppCellrenal_cortex_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Renal_corpuscle_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

7.68e-05183554848fc6dd129150897ee339343e83c645b6e779eb
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

7.68e-05183554eb559ae3ae252d9365c24ef557dd49b78ed6d898
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Epithelial-Renal_corpuscle_epithelial_cell|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

7.68e-051835547c4b775f351794a3de06bd503eecbc8ae8577c44
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell-Podocyte|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

8.01e-051855549197f074e769d54031ec41abfc65fcc0c6552c7e
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell-glomerular_visceral_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

8.01e-05185554ce7d62394b09c26ca65b8cdb280afec5e25bbb62
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Renal_corpuscle_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

PCED1B NPHS1 DDN LARGE1

8.01e-05185554b848b63aff4d9dbb9e66a85876d4c7c6dacd0579
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma-Acinar_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

TTLL12 VPS37C TRPM4 MOGS

8.01e-051855549d53e0a92e4f99370be2e4be1dd737630796b1ca
ToppCellTCGA-Prostate-Primary_Tumor-Prostate_Adenocarcinoma|TCGA-Prostate / Sample_Type by Project: Shred V9

TTLL12 VPS37C TRPM4 MOGS

8.35e-05187554fa0452f3382c22c0391b241d06504fda3c6a19f0
ToppCellTCGA-Prostate-Primary_Tumor|TCGA-Prostate / Sample_Type by Project: Shred V9

TTLL12 VPS37C TRPM4 MOGS

8.35e-051875543e6a95c912dad5d61e10497ffaafd2b9027cd13a
ToppCell(3)_MNP-(3)_DC_activated|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)

SLCO5A1 CD70 EPX DNAH11

9.06e-051915540353bf797c4ef237b9bb82460c173c7d03cb8883
ToppCellVE-mDC1-|VE / Condition, Cell_class and T cell subcluster

ZMYND15 SLCO5A1 MYLK SPINT1

9.43e-051935545df6033bc0e4f96a20d526486a8e89c990e21831
ToppCellVE-mDC1|VE / Condition, Cell_class and T cell subcluster

ZMYND15 SLCO5A1 MYLK SPINT1

9.43e-0519355412b2708db9db8b88365b8ebeb4908f28c50081bb
ToppCellTransverse-(5)_Dendritic_cell-(53)_Lymphoid_DC|Transverse / shred on region, Cell_type, and subtype

SLCO5A1 VPS37C TRPM4 EPX

1.02e-0419755415b87fd3906d7388c271d30d0c64b1bcc490801c
ToppCellTransverse-Dendritic_cell-Lymphoid_DC|Transverse / Region, Cell class and subclass

SLCO5A1 VPS37C TRPM4 EPX

1.02e-04197554a58af0ea82f76f2a7abac1f62629ff20d552fc63
ToppCellTracheal-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

SLCO5A1 MYLK RGS3 DNAH11

1.04e-0419855422e766df1276c5b14aa0d83f434f47140ebb98ea
ToppCellSigmoid-(5)_Dendritic_cell-(50)_cDC2|Sigmoid / shred on region, Cell_type, and subtype

ZMYND15 TICRR CSF1R SPINT1

1.06e-04199554402af84db90d8a49d67cf44c24766aefb00fd716
ToppCellSigmoid-Dendritic_cell-cDC2|Sigmoid / Region, Cell class and subclass

ZMYND15 TICRR CSF1R SPINT1

1.06e-04199554cd74db6db694b68f81dcf9d9342d125d00357ec1
Diseasemultiple myeloma

TICRR LGALS12 DNAH11

9.71e-04112513EFO_0001378
Diseasevisceral heterotaxy (implicated_via_orthology)

MMP21 DNAH11

1.88e-0337512DOID:0050545 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
PRAGPARLSPAAGYW

BTNL9

406

Q6UXG8
RFGPQGWSRSYPFNP

DNAH11

4096

Q96DT5
AGRGWARTPGPYAGA

DDN

596

O94850
PRLYWQGGPALGRSF

CD70

71

P32970
YFERLPGGGWTLRRT

DYRK1B

346

Q9Y463
AAVPRGARAGRWYRG

R3HCC1

116

Q9Y3T6
YRGRPSWQGTPGVLR

RLN3

101

Q8WXF3
SLPFGRRLYSGPWRS

RGS3

61

P49796
WTFRGYRLSPAGGPR

NPHS1

681

O60500
RPWPALGRGYNTGVI

LARGE1

286

O95461
GGSDRYGSLRPGWPA

MYLK

841

Q15746
RLGYAAPPAGRSSAW

MCUR1

96

Q96AQ8
EGFSRGIFRFLPWRG

LRRC37A2

1616

A6NM11
EGFSRGIFRFLPWRG

LRRC37A

1616

A6NMS7
GFPGASPRASRRRAW

MYO15A

756

Q9UKN7
IGFGRSCWSRGTPFP

JAG2

866

Q9Y219
GGRAPGTRIYSWSCP

LGALS12

6

Q96DT0
SLSRRGWQPRGYPDG

MMP21

151

Q8N119
LPFGWTPSRRRNGFL

EPX

181

P11678
GRYRPRGPYTPWGQR

PCED1B

401

Q96HM7
LYRWLPSRRGGVSGF

DERL1

206

Q9BUN8
RGAGDPARYLSPGWG

LARP6

41

Q9BRS8
SQAGPLPLSYRWRGR

MOGS

551

Q13724
WRRIPGGYSAPSFSP

CCSER2

771

Q9H7U1
AGRYSFLARNPGGWR

CSF1R

376

P07333
GRPAPLYDLGWYRPS

LACTBL1

236

A8MY62
GRGPSAELASRYWGR

DOCK8-AS1

221

Q5T8R8
GWLRGEPGAPSRYLG

C6orf47

156

O95873
GGARGRRRLPTFWPS

FRMD6-AS1

261

P0C7T7
RALRPRGLWGFYGFP

HYAL1

191

Q12794
GNYRFDPRSGPWNRG

SCAF8

1126

Q9UPN6
SVAWGPSRGRGGYIP

RPUSD2

391

Q8IZ73
FWPLYEAASGRGLRP

SAP25

41

Q8TEE9
GSWGCSRLRFGPPAY

PMPCA

16

Q10713
VAGYWPHRAGAPGSR

TMEM200B

71

Q69YZ2
TGYLPGRGRVLSSWS

RHOBTB2

376

Q9BYZ6
SYFGGRGRRPLWLAV

SLCO5A1

186

Q9H2Y9
YGFRGPGPQLRRGWR

CHGA

381

P10645
PSPRWGLGCGRVRYP

LINC01465

46

Q8N7H1
PTRFSYKGRNPFWRG

C11orf42

271

Q8N5U0
WLTYRRDFPPLPGGC

ATG4D

121

Q86TL0
ERRGYPGPGLRSDWH

TICRR

1436

Q7Z2Z1
PKYPRRGWGGFYQRA

SPEM2

196

Q0P670
VGRCRGSFPRWYYDP

SPINT1

256

O43278
GVEPGSQRWFFSGRP

UBTD2

186

Q8WUN7
GRLPAWPGAYGAPRA

nan

161

Q7L0L9
WYASRGIRPVGRFGR

PRLH

41

P81277
ARYVPRSPPWAGAGG

PPP1R3F

196

Q6ZSY5
ARGPTPYWRLRLGGA

PTTG1IP

6

P53801
SSRREPPPYGYRKGW

SNW1

36

Q13573
GPALRASGVPERYWG

TTLL12

36

Q14166
RGPGPRRSDWFLYDC

TMEM221

101

A6NGB7
GPRGAAGYSWSPQRS

VPS37C

251

A5D8V6
TWGPRPGFTFASLRA

ZMYND15

296

Q9H091
FRGRPYRGGSRWSRG

ZFC3H1

146

O60293
INPKGSFPARYRWRG

TRPM4

201

Q8TD43