Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionhemoglobin beta binding

HBB HBD

1.11e-052672GO:0031722
GeneOntologyMolecularFunctionhemoglobin alpha binding

HBB HBD

1.10e-045672GO:0031721
GeneOntologyMolecularFunctionhaptoglobin binding

HBB HBD

4.91e-0410672GO:0031720
GeneOntologyMolecularFunctionhemoglobin binding

HBB HBD

5.98e-0411672GO:0030492
GeneOntologyCellularComponentDNA-dependent protein kinase complex

PRKDC XRCC6

1.01e-045672GO:0070418
GeneOntologyCellularComponentDNA-dependent protein kinase-DNA ligase 4 complex

PRKDC XRCC6

2.10e-047672GO:0005958
GeneOntologyCellularComponentnonhomologous end joining complex

PRKDC XRCC6

3.59e-049672GO:0070419
GeneOntologyCellularComponenthaptoglobin-hemoglobin complex

HBB HBD

6.54e-0412672GO:0031838
GeneOntologyCellularComponenthemoglobin complex

HBB HBD

6.54e-0412672GO:0005833
Domain-

RASA4 RASA4B

3.79e-0536724.10.1130.10
DomainFATC

MTOR PRKDC

1.26e-045672PF02260
DomainHaemoglobin_b

HBB HBD

1.26e-045672IPR002337
DomainFAT

MTOR PRKDC

1.88e-046672PS51189
DomainFATC

MTOR PRKDC

1.88e-046672PS51190
DomainFAT

MTOR PRKDC

1.88e-046672PF02259
DomainPIK-rel_kinase_FAT

MTOR PRKDC

1.88e-046672IPR003151
DomainFATC_dom

MTOR PRKDC

1.88e-046672IPR003152
DomainPIK_FAT

MTOR PRKDC

1.88e-046672IPR014009
DomainFATC

MTOR PRKDC

1.88e-046672SM01343
DomainZF_CCHHC

L3MBTL1 L3MBTL3

2.63e-047672PS51802
DomainBTK

RASA4 RASA4B

4.49e-049672SM00107
DomainMBT

L3MBTL1 L3MBTL3

4.49e-049672SM00561
DomainZnf_Btk_motif

RASA4 RASA4B

4.49e-049672IPR001562
DomainMBT

L3MBTL1 L3MBTL3

4.49e-049672PS51079
DomainBTK

RASA4 RASA4B

4.49e-049672PF00779
DomainZF_BTK

RASA4 RASA4B

4.49e-049672PS51113
DomainMBT

L3MBTL1 L3MBTL3

5.60e-0410672PF02820
Domain-

TEX13C EWSR1

5.60e-04106724.10.1060.10
DomainMbt

L3MBTL1 L3MBTL3

5.60e-0410672IPR004092
DomainTGc

KY TGM6

6.83e-0411672SM00460
DomainTransglut_core

KY TGM6

6.83e-0411672PF01841
DomainTransglutaminase-like

KY TGM6

6.83e-0411672IPR002931
DomainGlobin

HBB HBD

8.18e-0412672IPR000971
DomainGlobin

HBB HBD

8.18e-0412672PF00042
DomainGLOBIN

HBB HBD

8.18e-0412672PS01033
Domain-

HBB HBD

9.64e-04136721.10.490.10
DomainGlobin/Proto

HBB HBD

9.64e-0413672IPR012292
DomainRasGAP

RASA4 RASA4B

1.12e-0314672SM00323
DomainRasGAP_CS

RASA4 RASA4B

1.12e-0314672IPR023152
DomainHEAT

MTOR PRKDC ECPAS

1.18e-0358673IPR000357
DomainRasGAP

RASA4 RASA4B

1.29e-0315672PF00616
DomainRAS_GTPASE_ACTIV_1

RASA4 RASA4B

1.29e-0315672PS00509
DomainRAS_GTPASE_ACTIV_2

RASA4 RASA4B

1.29e-0315672PS50018
DomainPI3/4_kinase_CS

MTOR PRKDC

1.29e-0315672IPR018936
DomainGlobin-like

HBB HBD

1.47e-0316672IPR009050
Domain-

RASA4 RASA4B

1.47e-03166721.10.506.10
Domain-

MTOR PRKDC

1.47e-03166721.10.1070.11
DomainPI3Kc

MTOR PRKDC

1.47e-0316672SM00146
DomainPDZ

AHNAK FRMPD2 SYNPO2L AHNAK2

1.65e-03141674PF00595
DomainPI3/4_kinase_cat_dom

MTOR PRKDC

1.87e-0318672IPR000403
DomainPI3_PI4_kinase

MTOR PRKDC

1.87e-0318672PF00454
DomainRasGAP_dom

RASA4 RASA4B

1.87e-0318672IPR001936
DomainPI3_4_KINASE_3

MTOR PRKDC

1.87e-0318672PS50290
DomainPI3_4_KINASE_1

MTOR PRKDC

1.87e-0318672PS00915
DomainPI3_4_KINASE_2

MTOR PRKDC

1.87e-0318672PS00916
DomainPDZ

AHNAK FRMPD2 SYNPO2L AHNAK2

1.97e-03148674SM00228
DomainHEAT_REPEAT

MTOR PRKDC ECPAS

2.03e-0370673PS50077
Domain-

AHNAK FRMPD2 SYNPO2L AHNAK2

2.07e-031506742.30.42.10
DomainPDZ

AHNAK FRMPD2 SYNPO2L AHNAK2

2.12e-03151674PS50106
DomainPDZ

AHNAK FRMPD2 SYNPO2L AHNAK2

2.17e-03152674IPR001478
DomainJmjC

PHF2 KDM3B

3.33e-0324672PF02373
DomainZF_RANBP2_1

TEX13C EWSR1

3.33e-0324672PS01358
Pubmed

The Nse5/6-like SIMC1-SLF2 complex localizes SMC5/6 to viral replication centers.

PHF2 AHNAK EWSR1 FAM98A PRKDC HBB HBD L3MBTL3 PLRG1 XRCC6 ISY1 ATP5F1B

3.01e-07954681236373674
Pubmed

Loss of ER retention motif of AGR2 can impact mTORC signaling and promote cancer metastasis.

ACADVL AHNAK ZNF805 EWSR1 PRKDC ECPAS HBB XRCC6 ATP5F1B AHNAK2 EPG5

4.51e-07807681130575818
Pubmed

BAP1 regulation of the key adaptor protein NCoR1 is critical for γ-globin gene repression.

PHF2 ACADVL AHNAK KDM3B MAK16 PRKCB EWSR1 FAM98A PRKDC HBB PLRG1 XRCC6 ATP5F1B

1.41e-061318681330463901
Pubmed

An E3 ubiquitin ligase, Really Interesting New Gene (RING) Finger 41, is a candidate gene for anxiety-like behavior and beta-carboline-induced seizures.

KDM3B HBB HBD

2.02e-061368318986647
Pubmed

A negative regulatory sequence near the mouse beta-maj globin gene associated with a region of potential Z-DNA.

HBB HBD

3.77e-0626826086313
Pubmed

Thrombocytopenia and erythrocytosis in mice with a mutation in the gene encoding the hemoglobin β minor chain.

HBB HBD

3.77e-06268222203977
Pubmed

Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.

MTOR PRKDC

3.77e-06268227235137
Pubmed

A humanized BAC transgenic/knockout mouse model for HbE/beta-thalassemia.

HBB HBD

3.77e-06268216631345
Pubmed

DNA-PKcs and Ku70 are predictive markers for poor prognosis of patients with gall bladder malignancies.

PRKDC XRCC6

3.77e-06268225046228
Pubmed

Perturbations in lipid metabolism and gut microbiota composition precede cardiac dysfunction in a mouse model of thalassemia.

HBB HBD

3.77e-06268237902616
Pubmed

Cloning specific segments of the mammalian genome: bacteriophage lambda containing mouse globin and surrounding gene sequences.

HBB HBD

3.77e-062682270684
Pubmed

Hepcidin as a therapeutic tool to limit iron overload and improve anemia in β-thalassemic mice.

HBB HBD

3.77e-06268221099112
Pubmed

A large upstream region is not necessary for gene expression or hypersensitive site formation at the mouse beta -globin locus.

HBB HBD

3.77e-06268211121056
Pubmed

Molecular and genetic crosstalks between mTOR and ERRα are key determinants of rapamycin-induced nonalcoholic fatty liver.

MTOR ESRRA

3.77e-06268223562079
Pubmed

Pleiotropic control of glucose and hormone responses by PRL1, a nuclear WD protein, in Arabidopsis.

PRKCB PLRG1

3.77e-0626829765207
Pubmed

A novel murine model of Cooley anemia and its rescue by lentiviral-mediated human beta-globin gene transfer.

HBB HBD

3.77e-06268212480689
Pubmed

CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.

RASA4 RASA4B

3.77e-06268211448776
Pubmed

Comparison of total sequence of a cloned rabbit beta-globin gene and its flanking regions with a homologous mouse sequence.

HBB HBD

3.77e-062682482942
Pubmed

Protein kinase C-β mediates neuronal activation of Na(+)/H(+) exchanger-1 during glutamate excitotoxicity.

SLC9A1 PRKCB

3.77e-06268224378530
Pubmed

Arginine supplementation of sickle transgenic mice reduces red cell density and Gardos channel activity.

HBB HBD

3.77e-06268211830454
Pubmed

Second generation knockout sickle mice: the effect of HbF.

HBB HBD

3.77e-06268211154217
Pubmed

Decreased hepcidin mRNA expression in thalassemic mice.

HBB HBD

3.77e-06268214675418
Pubmed

Nucleotide sequences of the mouse globin beta gene cDNAs in a wild derived new haplotype Hbb(w1).

HBB HBD

3.77e-06268210441738
Pubmed

Hematopoietic stem cell function in β-thalassemia is impaired and is rescued by targeting the bone marrow niche.

HBB HBD

3.77e-06268232344432
Pubmed

Responses of primary osteoblasts and osteoclasts from hemizygous β-globin knockout thalassemic mice with elevated plasma glucose to 1,25-dihydroxyvitamin D3.

HBB HBD

3.77e-06268231562377
Pubmed

The complete nucleotide sequence of a beta-globin-like structure, beta h2, from the [Hbb]d mouse BALB/c.

HBB HBD

3.77e-0626826736028
Pubmed

Running exercise alleviates trabecular bone loss and osteopenia in hemizygous β-globin knockout thalassemic mice.

HBB HBD

3.77e-06268224780610
Pubmed

Effects of human gamma-globin in murine beta-thalassaemia.

HBB HBD

3.77e-06268216803575
Pubmed

First report on the co-inheritance of beta-globin IVS-I-5 (G-->C) thalassemia with delta globin CD12 {Asn-->Lys (AAT-->AAA)}HbA₂-NYU in Iran.

HBB HBD

3.77e-06268221194254
Pubmed

DNA-PK, Nuclear mTOR, and the Androgen Pathway in Prostate Cancer.

MTOR PRKDC

3.77e-06268232209447
Pubmed

The adult beta-globin genes of the "single" type mouse C57BL.

HBB HBD

3.77e-0626827237554
Pubmed

Significance of borderline hemoglobin A2 values in an Italian population with a high prevalence of beta-thalassemia.

HBB HBD

3.77e-06268218603555
Pubmed

Comparison of cloned rabbit and mouse beta-globin genes showing strong evolutionary divergence of two homologous pairs of introns.

HBB HBD

3.77e-062682264241
Pubmed

Lack of neighborhood effects from a transcriptionally active phosphoglycerate kinase-neo cassette located between the murine beta-major and beta-minor globin genes.

HBB HBD

3.77e-06268211418464
Pubmed

Hepcidin and 1,25(OH)2D3 effectively restore Ca2+ transport in β-thalassemic mice: reciprocal phenomenon of Fe2+ and Ca2+ absorption.

HBB HBD

3.77e-06268227245334
Pubmed

Co-inheritance of alpha- and beta-thalassaemia in mice ameliorates thalassaemic phenotype.

HBB HBD

3.77e-06268217493845
Pubmed

An altered REDOX environment, assisted by over-expression of fetal hemoglobins, protects from inflammatory colitis and reduces inflammatory cytokine expression.

HBB HBD

3.77e-06268228641125
Pubmed

Role of polymorphic XRCC6 (Ku70)/XRCC7 (DNA-PKcs) genes towards susceptibility and prognosis of lung cancer patients undergoing platinum based doublet chemotherapy.

PRKDC XRCC6

3.77e-06268229397516
Pubmed

A mouse model for beta 0-thalassemia.

HBB HBD

3.77e-0626828524813
Pubmed

Mechanisms of enhanced thrombus formation in cerebral microvessels of mice expressing hemoglobin-S.

HBB HBD

3.77e-06268221304105
Pubmed

Reversal of hemochromatosis by apotransferrin in non-transfused and transfused Hbbth3/+ (heterozygous B1/B2 globin gene deletion) mice.

HBB HBD

3.77e-06268225616571
Pubmed

In vivo hematopoietic stem cell gene therapy ameliorates murine thalassemia intermedia.

HBB HBD

3.77e-06268230422819
Pubmed

β-Globin cis-elements determine differential nuclear targeting through epigenetic modifications.

HBB HBD

3.77e-06268224297746
Pubmed

Cloning and amplification of alpha and beta mouse globin gene sequences synthesised in vitro.

HBB HBD

3.77e-062682338418
Pubmed

Nephrectomy Does not Exacerbate Cancellous Bone loss in Thalassemic Mice.

HBB HBD

3.77e-06268232385316
Pubmed

The AHNAKs are a class of giant propeller-like proteins that associate with calcium channel proteins of cardiomyocytes and other cells.

AHNAK AHNAK2

3.77e-06268215007166
Pubmed

The evolution and sequence comparison of two recently diverged mouse chromosomal beta--globin genes.

HBB HBD

3.77e-062682519759
Pubmed

Murine cell line SX9 bearing a mutation in the dna-pkcs gene exhibits aberrant V(D)J recombination not only in the coding joint but also in the signal joint.

PRKDC XRCC6

3.77e-0626829582343
Pubmed

Intragenic motifs regulate the transcriptional complexity of Pkhd1/PKHD1.

PKHD1 PRKDC

3.77e-06268224984783
Pubmed

AHNAK1 and AHNAK2 are costameric proteins: AHNAK1 affects transverse skeletal muscle fiber stiffness.

AHNAK AHNAK2

3.77e-06268220833135
Pubmed

Neutralizing the function of a β-globin-associated cis-regulatory DNA element using an artificial zinc finger DNA-binding domain.

HBB HBD

3.77e-06268223074246
Pubmed

Humanized beta-thalassemia mouse model containing the common IVSI-110 splicing mutation.

HBB HBD

3.77e-06268216421096
Pubmed

High phosphate intake induces bone loss in nephrectomized thalassemic mice.

HBB HBD

3.77e-06268235622784
Pubmed

A humanized mouse model for a common beta0-thalassemia mutation.

HBB HBD

3.77e-06268215780748
Pubmed

Deletion and replacement of the mouse adult beta-globin genes by a "plug and socket" repeated targeting strategy.

HBB HBD

3.77e-0626827935410
Pubmed

Evolution of the mouse beta-globin genes: a recent gene conversion in the Hbbs haplotype.

HBB HBD

3.77e-0626823870864
Pubmed

Successful treatment of murine beta-thalassemia intermedia by transfer of the human beta-globin gene.

HBB HBD

3.77e-06268211877258
Pubmed

Hepatitis C virus-core protein facilitates the degradation of Ku70 and reduces DNA-PK activity in hepatocytes.

PRKDC XRCC6

3.77e-06268219467273
Pubmed

Molecular characterization of (deltabeta)(0)/beta(0)-thalassemia and (deltabeta)(0)-thalassemia/hemoglobin E in Thai patients.

HBB HBD

3.77e-06268211860449
Pubmed

Tracking of mouse cell lineage using microinjected DNA sequences: analyses using genomic Southern blotting and tissue-section in situ hybridizations.

HBB HBD

3.77e-0626823428512
Pubmed

The molecular characterization of an A:T to G:C transition in the Hbb-b1 gene of the murine homologue of hemoglobin Rainier.

HBB HBD

3.77e-0626821820025
Pubmed

Super-resolution imaging reveals three-dimensional folding dynamics of the β-globin locus upon gene activation.

HBB HBD

3.77e-06268222767512
Pubmed

Transgene copy number-dependent rescue of murine beta-globin knockout mice carrying a 183 kb human beta-globin BAC genomic fragment.

HBB HBD

3.77e-06268215820143
Pubmed

The beta-delta crossover leading to the beta delta hybrid gene of hemoglobin P-Nilotic is located within 54 base-pairs of the 5' end of exon 2 or between codons 31 and 50.

HBB HBD

3.77e-0626823620470
Pubmed

An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.

RASA4 RASA4B

3.77e-06268216041389
Pubmed

Growth retardation and leaky SCID phenotype of Ku70-deficient mice.

PRKDC XRCC6

3.77e-0626829390689
Pubmed

Model mice for Presbyterian hemoglobinopathy (Asn(beta108)-->Lys) confer hemolytic anemia with altered oxygen affinity and instability of Hb.

HBB HBD

3.77e-06268212127975
Pubmed

The sequence of the chromosomal mouse beta-globin major gene: homologies in capping, splicing and poly(A) sites.

HBB HBD

3.77e-062682569555
Pubmed

The chromatin "landscape" of a murine adult β-globin gene is unaffected by deletion of either the gene promoter or a downstream enhancer.

HBB HBD

3.77e-06268224817273
Pubmed

Ligation-mediated amplification of RNA from murine erythroid cells reveals a novel class of beta globin mRNA with an extended 5'-untranslated region.

HBB HBD

3.77e-0626828041612
Pubmed

A 66-base pair insert bridges the deletion responsible for a mouse model of beta-thalassemia.

HBB HBD

3.77e-0626823017971
Pubmed

The pyruvate kinase activator mitapivat reduces hemolysis and improves anemia in a β-thalassemia mouse model.

HBB HBD

3.77e-06268233822774
Pubmed

Evaluation of Stem Cell-Derived Red Blood Cells as a Transfusion Product Using a Novel Animal Model.

HBB HBD

3.77e-06268227959920
Pubmed

Intervening sequence of DNA identified in the structural portion of a mouse beta-globin gene.

HBB HBD

3.77e-062682273235
Pubmed

Mouse haemoglobin beta chains. Comparative sequence data on adult major and minor beta chains from two species, Mus musculus and Mus cervicolor.

HBB HBD

3.77e-062682999642
Pubmed

Integrated protein quality-control pathways regulate free α-globin in murine β-thalassemia.

HBB HBD

3.77e-06268222427201
Pubmed

Mild-intensity physical activity prevents cardiac and osseous iron deposition without affecting bone mechanical property or porosity in thalassemic mice.

HBB HBD

3.77e-06268235396390
Pubmed

Heparanase Level and Procoagulant Activity Are Increased in Thalassemia and Attenuated by Janus Kinase 2 Inhibition.

HBB HBD

3.77e-06268232745462
Pubmed

Molecular characterization of a novel homozygous deletion in β-globin cluster causing (δβ)0-Thalassemia among Tunisian family.

HBB HBD

3.77e-06268236214153
Pubmed

The isolation and characterization of linked delta- and beta-globin genes from a cloned library of human DNA.

HBB HBD

3.77e-062682728996
Pubmed

Expression of HbC and HbS, but not HbA, results in activation of K-Cl cotransport activity in transgenic mouse red cells.

HBB HBD

3.77e-06268214615383
Pubmed

CNTO 530 increases expression of HbA and HbF in murine models of β-thalassemia and sickle cell anemia.

HBB HBD

3.77e-06268223157711
Pubmed

HbA2-Partinico or delta(A2)Pro-->Thr, a new genetic variation in the delta-globin gene in cis to the beta(+) thal IVS-I-110 G>A, and the heterogeneity of delta-globin alleles in double heterozygotes for beta- and delta-globin gene defects.

HBB HBD

3.77e-06268219609526
Pubmed

Discovery of a new HBB haplotype w2 in a wild-derived house mouse, Mus musculus.

HBB HBD

3.77e-06268218299925
Pubmed

Hemoglobin induction in mouse macrophages.

HBB HBD

3.77e-06268210359765
Pubmed

Evolution of duplicated beta-globin genes and the structural basis of hemoglobin isoform differentiation in Mus.

HBB HBD

3.77e-06268219675095
Pubmed

Transposition of a long member of the L1 major interspersed DNA family into the mouse beta globin gene locus.

HBB HBD

3.77e-0626822991851
Pubmed

Quantitative Proteomics Reveals Dynamic Interactions of the Minichromosome Maintenance Complex (MCM) in the Cellular Response to Etoposide Induced DNA Damage.

GGH ACADVL AHNAK EWSR1 FAM98A PRKDC HBB HBD XRCC6 ATP5F1B

5.48e-06844681025963833
Pubmed

Role of the non-homologous DNA end joining pathway in the early steps of retroviral infection.

PRKDC XRCC6

1.13e-05368211406603
Pubmed

Abnormal DNA-PKcs and Ku 70/80 expression may promote malignant pathological processes in gastric carcinoma.

PRKDC XRCC6

1.13e-05368224187467
Pubmed

A mouse model of β-thalassemia shows a liver-specific down-regulation of Abcc6 expression.

HBB HBD

1.13e-05368221281810
Pubmed

An erythroid chaperone that facilitates folding of alpha-globin subunits for hemoglobin synthesis.

HBB HBD

1.13e-05368217607360
Pubmed

Decreasing TfR1 expression reverses anemia and hepcidin suppression in β-thalassemic mice.

HBB HBD

1.13e-05368228151426
Pubmed

Mapping of protein-protein interactions within the DNA-dependent protein kinase complex.

PRKDC XRCC6

1.13e-05368210446239
Pubmed

Oxygen affinity of hemoglobin regulates O2 consumption, metabolism, and physical activity.

HBB HBD

1.13e-05368212458204
Pubmed

Deletion of individual Ku subunits in mice causes an NHEJ-independent phenotype potentially by altering apurinic/apyrimidinic site repair.

PRKDC XRCC6

1.13e-05368224466051
Pubmed

The DNA-PK catalytic subunit regulates Bax-mediated excitotoxic cell death by Ku70 phosphorylation.

PRKDC XRCC6

1.13e-05368219664609
Pubmed

In vivo blood flow abnormalities in the transgenic knockout sickle cell mouse.

HBB HBD

1.13e-05368210079113
Pubmed

Decreased hepcidin expression in murine β-thalassemia is associated with suppression of Bmp/Smad signaling.

HBB HBD

1.13e-05368222461476
Pubmed

Secondary structure of mouse and rabbit alpha- and beta-globin mRNAs: differential accessibility of alpha and beta initiator AUG codons towards nucleases.

HBB HBD

1.13e-0536827357610
CytobandEnsembl 112 genes in cytogenetic band chr13q14

ATP7B ALG11 FNDC3A NUFIP1

4.86e-04244684chr13q14
Cytoband2q24.1

DAPL1 GALNT5

7.41e-04276822q24.1
Cytoband13q14.2

ALG11 FNDC3A

7.41e-042768213q14.2
Cytoband10q22.2

ZSWIM8 SYNPO2L

1.71e-034168210q22.2
GeneFamilySterile alpha motif domain containing|MBT domain containing

L3MBTL1 L3MBTL3

2.06e-0494421263
GeneFamilyHemoglobin subunits

HBB HBD

2.57e-0410442940
GeneFamilyPleckstrin homology domain containing|SH2 domain containing|C2 and RasGAP domain containing

RASA4 RASA4B

2.57e-0410442830
GeneFamilyPDZ domain containing

AHNAK FRMPD2 SYNPO2L AHNAK2

5.02e-041524441220
GeneFamilyPHD finger proteins|Lysine demethylases

PHF2 KDM3B

1.54e-0324442485
ToppCelldroplet-Marrow-BM-1m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN CTSA F10

6.52e-061696958066b4c02c97d00034802cff2b39799ef44cc904
ToppCelldroplet-Marrow-nan-18m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN CTSA F10

7.72e-06175695510c46bfd250ef83fcad8f6b01efbcca9d71a9a2
ToppCelldroplet-Marrow-nan-24m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN CTSA F10

7.94e-06176695eddac2ba68d234e3f56f4ca0e11c19bc0e95b6e1
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN CTSA F10

7.94e-061766951bf8fed48bd224f09efe90a38233b1f01d7311fe
ToppCellCOVID-19_Mild-Lymphoid_T/NK-NK_activated|COVID-19_Mild / Disease group, lineage and cell class

AHNAK PRSS23 ECPAS ATP5F1B MYBL1

8.16e-061776956978a22fef40c8b455342373abe7593f5ede0fa4
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHNAK VCAN ECPAS RIC1 ATP5F1B

1.18e-05191695c9f3bdb5c0a90268cab24a0fe4c3a8290fcedeb8
ToppCellPBMC-Mild-Myeloid-Classical_Monocyte-Classical_Monocyte-cMono_1|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHNAK VCAN ECPAS RIC1 ATP5F1B

1.21e-05192695b86476037ddf8904c1d8a6b3763af7242c031cf3
ToppCell10x5'-bone_marrow|World / Manually curated celltypes from each tissue

ITPRIP PRSS23 HBB HBD ATP5F1B

1.21e-0519269534777fa7dc001b6d601376a23aab995e2cec043c
ToppCell343B-Lymphocytic-ILC-ILC-1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

MTFR1 ZBTB21 HBB CTSA L3MBTL3

1.21e-05192695445985fe1bcd33e4f0a1704b27988fbfc9334538
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN CTSA F10

1.24e-051936955a201ee6f132357c9aacfbad3ae56ed9854c25fd
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|Classical_Monocyte / Disease condition and Cell class

AHNAK VCAN ECPAS RIC1 ATP5F1B

1.34e-0519669515397ec27167bb2fb6fec120b68bf38fc71b2670
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_3|COVID-19_Mild / Disease condition and Cell class

AHNAK VCAN ECPAS RIC1 ATP5F1B

1.34e-05196695f245e929a286cb097130572e1027b4f01be8b04d
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AHNAK CCDC190 PRSS23 HBB AHNAK2

1.37e-051976955c4cee914baf7cb43e9cb99cc9e3ae823856dc15
ToppCellkidney_cells-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

KANSL1 AHNAK VCAN PKHD1 CHD9

1.44e-05199695174f6013af6eafa577f84205a62927f2b367fda3
ToppCellremission-multiplets|World / disease stage, cell group and cell class

HBD NLGN2 HBB MYBL1

7.01e-05142694286d01b4f95e9c0b38b91958f925f3797dffd596
ToppCellfacs-Marrow-T-cells-24m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

9.13e-05152694d279592c501fca9cb474ad916fea32282e6969cb
ToppCellfacs-Marrow-T-cells-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

9.13e-051526943b59143b2b4ee24eb6378f87ff568124193256e9
ToppCell11.5-Distal-RBC|Distal / Age, Tissue, Lineage and Cell class

DNAJB13 HBD GALNT5 HBB

1.19e-04163694e9d814952d824539ff1dea119e4fca14a8c335a8
ToppCell11.5-Distal-RBC-RBC|Distal / Age, Tissue, Lineage and Cell class

DNAJB13 HBD GALNT5 HBB

1.19e-0416369431b60e065bac4ad380247964e7574f210106ebae
ToppCellfacs-Marrow-T_cells-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

1.19e-0416369430cd95d4f37bd54c1fde54960cb005db58bdd30c
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK PRKCB CHD9 HBB

1.19e-041636946bed27d2f67a430a847da5eb47878d14b4949c45
ToppCellfacs-Marrow-T_cells-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

1.19e-04163694ab934cb986495adfc8dbe5a276577f2a8fb6ee03
ToppCellCOVID-19_Mild-Classical_Monocyte-cMono_1|COVID-19_Mild / Disease condition and Cell class

VCAN ECPAS RIC1 ATP5F1B

1.25e-04165694ef709c5d3231c65d351316e1e31b9c9eba721628
ToppCellICU-NoSEP-Lymphocyte-T_NK-CD4_CTL|ICU-NoSEP / Disease, Lineage and Cell Type

DNAJB13 CCDC190 PRSS23 MYBL1

1.37e-04169694cbda36f32bd78322dcfe303a44413415d08e5ea3
ToppCell10x_3'_v3-tissue-resident_(10x_3'_v3)-hematologic-erythrocytic-erythroid_lineage_cell|tissue-resident_(10x_3'_v3) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type

DAPL1 HBD GALNT5 HBB

1.40e-04170694288014dedda8babc51fe08e48a55e68d83e1b1d2
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

1.50e-04173694807183fc23478da9451906dacd88de4e73112e0d
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d02_child-Lymphocytic-Lymphocytic_B-B_cell|Mild-Moderate_progression_d02_child / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK PRKCB CHD9 HBB

1.50e-04173694d56e337eae727a29cd53cfd628e1b3c0a98e1f51
ToppCellfacs-Marrow-Granulocytes-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

1.50e-041736942e683ec555dc0036875e0f5674dcc5e93ead205d
ToppCellTCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell|TCGA-Thryoid / Sample_Type by Project: Shred V9

VCAN CTSA PLRG1 AHNAK2

1.50e-041736942e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCellImmune_cells-Monocytes|Immune_cells / Lineage and Cell class

GGH AHNAK CTSA F10

1.50e-041736943eced40a65453a023a1673658592e7e2a099119b
ToppCelldroplet-Marrow-BM-30m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

1.54e-04174694118ba2729ecc6aa1bb8548f3cf537b3f9e902ef0
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-monocyte_+_promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN F10

1.57e-0417569469b59ec58e64644deb7e07f31ef495ef4a6f6276
ToppCell356C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_6|CD8+_Cytotoxic_T-cell / Donor, Lineage, Cell class and subclass (all cells)

DAPL1 ANKRD26 MAP3K13 EPG5

1.57e-04175694f3a68aeb79c4935006e17a5ff3445a8ec0e33f5f
ToppCellfacs-Marrow-Granulocytes-3m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK VCAN F10

1.57e-041756944f7498b5a0ed52c348a5f94bcd41d830ba7954ea
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHNAK ECPAS ATP5F1B MYBL1

1.64e-04177694d3e6c768b88b7906f3c7fdd00ba20842212c14b1
ToppCellHealthy-RBC|World / disease group, cell group and cell class

VCAN HBD GALNT5 HBB

1.64e-041776942ce41e37fa7139c7bd2b464bd86c5601dc501515
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AHNAK ECPAS ATP5F1B MYBL1

1.64e-04177694f8f101c772c043636bedd6b2ec81409b1d2599bf
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

AHNAK ECPAS ATP5F1B MYBL1

1.64e-04177694936ab2b180a052387124f68d0c7f41c0b164e748
ToppCellPBMC-Mild-Lymphocyte-T/NK-NK_cell-NK_activated-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AHNAK ECPAS ATP5F1B MYBL1

1.64e-04177694d5aeda113afaa2425874394610344570c9078478
ToppCelldroplet-Marrow-nan-21m-Myeloid-monocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK CTSA F10

1.64e-04177694b860013f1fd397400a62d66ab521cfc81349ffe2
ToppCelldroplet-Marrow-BM_(NON-STC)-30m-Myeloid-basophil|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

AHNAK VCAN CTSA F10

1.68e-041786941a578d16008a450c42e73a996247ffecdc2c43f0
ToppCellCOVID-19_Severe-Classical_Monocyte-cMono_1|COVID-19_Severe / Disease condition and Cell class

AHNAK VCAN ECPAS ATP5F1B

1.79e-041816940d07a67e8ee3bca687b378afbc4044434e63556d
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_1|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRKCB ITPRIP PRSS23 MYBL1

1.86e-04183694983ca1342ddd365e1f1df32a456394b002b10e41
ToppCelldroplet-Marrow-nan-3m-Myeloid-Cd4_positive_Macrophages|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA4 ECPAS L3MBTL3 NUFIP1

1.86e-0418369492ef926e6c1de8477fa4f35d1dae85482d8009de
ToppCelldroplet-Marrow-nan-3m-Myeloid-macrophage|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

RASA4 ECPAS L3MBTL3 NUFIP1

1.86e-0418369424db9cc717e651586317c6a8e03a3401651273c1
ToppCellCOVID-19_Severe-gd_T|COVID-19_Severe / Disease condition and Cell class

AHNAK PRSS23 ATP5F1B MYBL1

1.90e-04184694791f1bcb954aadc63d4117c400537d036f68734d
ToppCell5'-Airway_Nasal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 AHNAK PRSS23 AHNAK2

1.94e-04185694e0172e0ab0f1d7151a3c3c63bb7c84d6bda92035
ToppCelldroplet-Marrow-BM-1m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK CTSA F10

2.02e-04187694028e7d6e1211e123879d2f353dc32fae1185dd8e
ToppCelltumor_Lymph_Node_/_Brain-Fibroblasts-Undetermined|tumor_Lymph_Node_/_Brain / Location, Cell class and cell subclass

ZNF219 ZNF805 NLGN2 L3MBTL3

2.06e-041886948231e635706a296db6b6da1029a33bbc1b52478e
ToppCell343B-Lymphocytic-ILC-ILC-1|343B / Donor, Lineage, Cell class and subclass (all cells)

MTFR1 ZBTB21 HBB L3MBTL3

2.06e-041886948f6b45ad82bde65e044d17f0edbc3db90d457915
ToppCell367C-Lymphocytic-NK_cells-NK_cell_B|NK_cells / Donor, Lineage, Cell class and subclass (all cells)

ZNF219 VCAN PRKCB PRSS23

2.11e-04189694160963355256f7c0f2138da80c90de478f5a9fe8
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51|PBMC_fresh-frozen / Compartment, severity and other cell annotations on 10x 3' data (130k)

KANSL1 AHNAK RASA4B MYBL1

2.11e-041896940e8d1be3c406d1a393e18faccfe89116a8f82bcf
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

GABRG1 GLDC PKHD1 MYBL1

2.11e-04189694c8b8f860aaf6c73863cd79941db6b469c830ef06
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-VLMC-G|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DAPL1 GALNT5 HBB F10

2.15e-04190694c90410bb47b8da774dee2a3502f667ce9a7c97d9
ToppCell10x_3'_v2v3-Non-neoplastic-Vascular-Mural_cell-VLMC|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group

DAPL1 GALNT5 HBB F10

2.15e-04190694bc44727e8458a02fae95dc5515b708000d2ee8c4
ToppCelldroplet-Marrow-nan-18m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK CTSA F10

2.15e-0419069495d8dc8488e95158e84a44bb53ea4ab7bf3d44bb
ToppCelldroplet-Marrow-nan-21m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK CTSA F10

2.15e-041906946c6d3259e23ec90c08756f500ae8a7aff8b8a5b3
ToppCelldroplet-Marrow-nan-24m-Myeloid-promonocyte|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

GGH AHNAK CTSA F10

2.15e-04190694e2fdbfaf08da3274b6bdda615386aa880040a90a
ToppCellNS-critical-d_16-33-Epithelial-Secretory-diff|d_16-33 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)

DAPL1 AHNAK PRSS23 GALNT5

2.24e-0419269402b11233b4da2d85b96498b3c6e22e3a31b3d049
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating2_(13)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

DOCK3 GLDC PKHD1 MYBL1

2.24e-0419269425378b5e4b0cea8415ff125783511fc25a56fc00
ToppCell10x5'-blood|World / Manually curated celltypes from each tissue

AHNAK VCAN HBB CTSA

2.28e-04193694359d4242a7e5e51a3eaf6fe51bc1c653a402b054
ToppCellkidney_cells-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

AHNAK VCAN UGT2A3 PKHD1

2.28e-041936940f2167eef8203a5659c8c72e4e77646003d64797
ToppCellMesenchymal_cells-Endosteal_fibro.|Mesenchymal_cells / Lineage and Cell class

AHNAK VCAN PRSS23 AHNAK2

2.33e-041946949a4b5de4d1d8a0aa76fed7b36548ea628f3009cc
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPATA31D1 PRSS23 HBB MYBL1

2.33e-04194694a3a81638b55cb5fc08fe83c8b88f68d49b87e6cb
ToppCell367C-Lymphocytic-CD8+_Cytotoxic_T-cell|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)

PRKCB ITPRIP PRSS23 MYBL1

2.33e-04194694a8dc3336aa4ef497f6d26cede02ddac425e7c655
ToppCellsystemic_lupus_erythematosus-treated-Lymphocytic_NK-natural_killer_cell-female|systemic_lupus_erythematosus / PBMC cell types (v2) per disease, treatment status, and sex

SPATA31D1 PRSS23 HBB MYBL1

2.33e-041946940abca32c3547a45cebab0bd69c1f7a0002deaa80
ToppCellCOVID-19_Severe-CD8+_Tem|COVID-19_Severe / Disease condition and Cell class

AHNAK PRKCB PRSS23 MYBL1

2.37e-04195694ff7ae62393e1c858a10592db8e6d9f36b8bae396
ToppCellMesenchymal_cells-Endosteal_fibro.|World / Lineage and Cell class

AHNAK VCAN PRSS23 AHNAK2

2.37e-04195694d53974d1866e23c894ffd492ea11d20422919b11
ToppCellMild/Remission-Plasmablast|Mild/Remission / disease group and sub_cluster of B and Plasma cells(res = 0.5)

GGH ACADVL GLDC FNDC3A

2.42e-04196694dcf0a804a79a05454658498d1f87320c7e079219
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.1|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

GGH DAPL1 PRSS23 AHNAK2

2.47e-041976941d4ccca2ff46fccb3ac052b5148cb7f94231d65a
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar-Macro_c3-EREG|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACADVL AHNAK VCAN XRCC6

2.47e-041976947293587c875738c1711b8a68d40303a197b01c32
ToppCellT_cells-CTLs|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

AHNAK PRKCB PRSS23 MYBL1

2.47e-0419769428117cf300e169182571fbad0de1681a484a435a
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACADVL AHNAK VCAN XRCC6

2.47e-0419769482072bd73634e1ef24dc193e860af7786727313b
ToppCell(2)_Fibroblasts-(23)_Fibro-4|World / Cell class and subclass of bone marrow stroma cells in homeostatis

GLDC ECM2 VCAN AHNAK2

2.47e-04197694a183919023a4aca90a06be0e5e89c817b38c5574
ToppCellMonocytes-NUPR1+_Monocytes|Monocytes / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ACADVL PRSS23 ATP5F1B AHNAK2

2.47e-041976948a058c9d9285acd7cf2fb8e34f7602a86b5d6c89
ToppCellsaliva-Severe-critical_progression_d12-22_no-steroids-Myeloid-Macrophage-macrophage,_alveolar|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)

ACADVL AHNAK VCAN XRCC6

2.47e-04197694b4869013f0523ac73c284e6cdaf64e9ae5213dc5
ToppCellT_cells-CTLs|World / Immune cells in Kidney/Urine in Lupus Nephritis

AHNAK PRKCB PRSS23 MYBL1

2.47e-041976942de34e20915a247bee75aa40495e23c20bb23e18
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal-Suprabasal_L.0.0.1.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 PRSS23 ATP5F1B AHNAK2

2.52e-041986949718f4c013c347f1b3c785ae232dd2fb6c1fe298
ToppCell3'-Broncho-tracheal-Epithelial-Airway_epithelium-respiratory_basal_cell-Suprabasal|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 PRSS23 ATP5F1B AHNAK2

2.52e-0419869489ec1e760a193441092571475cc66a3b425f232e
ToppCellParenchymal-10x5prime-Hematologic-Erythrocyte-Erythrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

UGT2A3 HBD HBB MYBL1

2.52e-04198694745e966fd52f06485061727cdbd9358b9df7d97d
ToppCellParenchymal-10x5prime-Hematologic|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

UGT2A3 HBD HBB MYBL1

2.52e-0419869424b1138746dd69d1cda419f7070ef5a402d07563
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.3|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 PRSS23 HBB ATP5F1B

2.52e-04198694e3d1c9428ee6f9bcf9cdaf2192d4ebea8cc2a47c
ToppCellFibroblasts-HLA-DRA_high_Fibroblasts|World / Immune cells in Rheumatoid Arthritis Joint Synovial Tissues

ECM2 VCAN NLGN2 PRSS23

2.52e-04198694e8c0fbf306fae13e97caa294d7c99a564bd97130
ToppCellParenchymal-10x5prime-Hematologic-Erythrocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

UGT2A3 HBD HBB MYBL1

2.52e-041986942a00648d3aa5843d9e924e054c5e973025f86e97
ToppCell(1)_Osterolineage_cells-(11)_OLC-2|(1)_Osterolineage_cells / Cell class and subclass of bone marrow stroma cells in homeostatis

ECM2 AHNAK PRSS23 AHNAK2

2.52e-041986949f9dcf23ffb333105263132d87b90095642294cf
ToppCellT/NK_cells-CD8+_Naive_T_cell|T/NK_cells / Lineage and Cell class

AHNAK PRKCB PRSS23 ATP5F1B

2.52e-041986945b78118af2283f2e1ad9c6a6ab448a018bf2f2e0
ToppCellSepsis-Leuk-UTI-Others|Leuk-UTI / Disease, condition lineage and cell class

GGH HROB HBD HBB

2.56e-04199694e45fe91f1d1c47a305b0f39d808730723852af00
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AHNAK PRSS23 GALNT5 HBB

2.56e-041996948bf8d7cd774479f065bbbbcb5a4bd1aa91aa0d85
ToppCellSepsis-Leuk-UTI-Others-RBC|Leuk-UTI / Disease, condition lineage and cell class

GGH HROB HBD HBB

2.56e-04199694d9b517199a646c9461c615412ad5b58cf4bed7c8
ToppCellsuprabasal_cell|World / shred by cell class for turbinate

DAPL1 AHNAK ATP5F1B AHNAK2

2.56e-04199694bfab5380ef074d14f0b5ed10851ad5c898eb9a58
ToppCell3'-GW_trimst-2-SmallIntestine-Mesenchymal-fibroblastic-Stromal_3_(C7+)|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ECM2 AHNAK VCAN PRSS23

2.56e-041996949846d6a31635fde759d55674631c11ab9270a603
ToppCellBronchial-NucSeq-Epithelial-Epi_alveolar-Dividing_AT2|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

GGH HROB ZGRF1 MYBL1

2.56e-041996941d5a3366474c17e3df0ba5cf11b586655529e9bd
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 AHNAK PRSS23 AHNAK2

2.56e-04199694ba284f984909504221900bca5ea12ada5b2ffd9f
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AHNAK PRSS23 GALNT5 HBB

2.56e-041996940c060ef64341659f4b1247d0264ac12e53a7e12e
ToppCell(2)_Fibroblasts-(24)_Fibro-5|World / Cell class and subclass of bone marrow stroma cells in homeostatis

ECM2 AHNAK VCAN AHNAK2

2.56e-041996946c0354f57883330c685a8d9d5d3014ace7eca584
ToppCellCOVID-19-COVID-19_Severe|COVID-19 / Disease, condition lineage and cell class

GGH HBD HBB CTSA

2.61e-042006943ec89071f002bb66d46146bf4804f91e6f09a36f
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d14-21-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683|Severe-critical_convalescent_d14-21 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AHNAK PRKCB PRSS23 MYBL1

2.61e-042006942bd8c35484fe6b0bc0f9314216786baaa97d1e95
ToppCell5'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 AHNAK PRSS23 GALNT5

2.61e-04200694b68d212159b9d04866ba02ff55c35be247805eec
ToppCell5'-Airway_Nasal-Epithelial|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

DAPL1 AHNAK PRSS23 GALNT5

2.61e-04200694358d71329921451c7f5a56f1db0f9989af2299dc
ToppCellCOVID_vent|World / Disease condition, Lineage, Cell class and subclass

GGH VCAN HBB CTSA

2.61e-042006941d88e5cc4534073f27a7562e1c4b884bd67f09d9
Drugsebacate

ACADVL MTOR PRKDC TGM6 HBB HBD XRCC6

9.37e-07181667CID000005192
Drugketononestrol aziridine

ESRRA HBB HBD

6.52e-0613663CID000130642
Drugtricapryl(methyl)ammonium

HBB HBD

8.28e-062662CID011071504
Drugallyl 2,4,6-tribromophenyl ether

HBB HBD

8.28e-062662CID000076767
Drug1,3,5-tribromobenzene

HBB HBD

8.28e-062662CID000012279
DrugAC1L3OJQ

HBB HBD

8.28e-062662CID000119294
Drugpentabromobenzene

HBB HBD

8.28e-062662CID000011854
Drugtribromobenzene

HBB HBD

8.28e-062662CID000011842
DrugBromkal 73-5 PE

HBB HBD

8.28e-062662CID000118216
Drug2-(alpha-hydroxybenzyl)-benzimidazole

HBB HBD

8.28e-062662CID000005792
DrugNSC-334295

HBB HBD

8.28e-062662CID000100107
DrugHarpagoside [19210-12-9]; Down 200; 8uM; HL60; HT_HG-U133A

SLC9A1 L3MBTL1 ECM2 AHNAK ESRRA ANKRD26

2.23e-051966662935_DN
DrugPirenperone [ 75444-65-4]; Down 200; 10.2uM; HL60; HT_HG-U133A

HROB SLC9A1 ZNF219 ATP7B L3MBTL1 ESRRA

2.36e-051986662455_DN
Drugfuryl-dihydropyridine I

HBB HBD

2.48e-053662CID000125806
DrugNx-D

HBB HBD

2.48e-053662CID006914638
Drugmer13

HBB HBD

2.48e-053662CID000107453
DrugBTBPE

HBB HBD

2.48e-053662CID000037840
Drugpentabromoethylbenzene

HBB HBD

2.48e-053662CID000006800
Drughyoscine-N-butylbromide

HBB HBD MYBL1

2.56e-0520663CID000003636
DrugAC1L2GOW

ITPRIP HBB HBD

2.56e-0520663CID000046762
Drugtamoxifen aziridine

ESRRA HBB HBD

3.44e-0522663CID003033894
DrugRges Peptide

FNDC3A HBB HBD

3.95e-0523663CID000121927
DrugAC1L4CDO

HBB HBD

4.95e-054662CID000154482
DrugHPED

HBB HBD

4.95e-054662CID000125856
DrugPTU-23

HBB HBD

4.95e-054662CID000853760
DrugIC86621

PRKDC XRCC6

4.95e-054662CID009859309
DrugAC1L9JVG

HBB HBD

4.95e-054662CID000446603
Drug4-(2-carboxyvinyl)benzoic acid

HBB HBD

4.95e-054662CID000089196
Drug1,4-dibromobenzene

HBB HBD

4.95e-054662CID000007804
Drug1,2,4,5-tetrabromobenzene

HBB HBD

4.95e-054662CID000012486
DrugH-Ni

PRKDC HBB HBD

7.24e-0528663CID000445665
DrugBile Acids and Salts

SLC9A1 ATP7B MTOR ATP5F1B

8.22e-0579664ctd:D001647
DrugAC1L8TD7

HBB HBD

8.23e-055662CID000407802
Drugarildone

HBB HBD

8.23e-055662CID000041782
Drug1,2,4-tribromobenzene

HBB HBD

8.23e-055662CID000012002
DrugCaBr2

HBB HBD

8.23e-055662CID000024608
DrugHexbbp

HBB HBD

8.23e-055662CID000119134
DrugAC1LA5IX

FNDC3A HBB HBD

9.87e-0531663CID000462147
DrugAC1ND2OB

MTOR ESRRA VCAN PRKCB HBB HBD

1.19e-04265666CID004568637
Drug2,4-pentanediol

HBB HBD

1.23e-046662CID000012262
Drugpentabromotoluene

HBB HBD

1.23e-046662CID000006906
DrugAC1LDLU6

HBB HBD

1.23e-046662CID000620919
Drugdiaspirin

ATP7B HBB HBD

1.31e-0434663CID000065042
DrugCortisporin

MTOR PRKCB HBB HBD ATP5F1B

1.63e-04177665CID000004454
DrugBP-6

HBB HBD XRCC6

1.68e-0437663CID000446948
Drugtriheptanoin

ACADVL MTOR

1.72e-047662CID000069286
Drugmedrylamine

HBB HBD

1.72e-047662CID000010669
Drugpurpald

HBB HBD

1.72e-047662CID002723946
DrugHBBA

HBB HBD

1.72e-047662CID016072199
DrugSV-4814

HBB HBD

1.72e-047662CID003010509
DrugViroxime

HBB HBD

1.72e-047662CID000051567
Drugtrimesic acid

HBB HBD

1.72e-047662CID000011138
Drug4-nitrosobiphenyl

HBB HBD

1.72e-047662CID000024971
Drugbp G

VCAN HBB HBD

1.97e-0439663CID000448110
Drugflourish

KY HBB HBD

1.97e-0439663CID000009291
DrugAC1L2B9U

HBB HBD

2.29e-048662CID000044164
DrugL 35

HBB HBD

2.29e-048662CID000195347
DrugAC1Q6S1Y

MTOR ESRRA HBB HBD

2.38e-04104664CID000122035
Drughaloperidol; Down 200; 10uM; HL60; HT_HG-U133A

SLC9A1 ZNF219 L3MBTL1 ESRRA SYNPO2L

2.56e-041956652663_DN
DrugDiphenylpyraline hydrochloride [132-18-3]; Down 200; 12.6uM; HL60; HT_HG-U133A

HROB SLC9A1 VCAN ANKRD26 FNDC3A

2.69e-041976652205_DN
DrugOrlistat; Down 200; 10uM; PC3; HT_HG-U133A

L3MBTL1 MTOR ECM2 MAP3K13 HBB

2.75e-041986656388_DN
Drugdansyl chloride

GGH TGM6 CTSA F10

2.75e-04108664CID000011801
DrugPiperine [94-62-2]; Up 200; 14uM; PC3; HT_HG-U133A

ZNF219 ECM2 AHNAK PRKCB HBB

2.81e-041996654247_UP
DrugRinger's lactate

ATP7B HBB HBD

2.83e-0444663CID006335487
Drug4-sulfophenyl isothiocyanate

HBB HBD

2.94e-049662CID000087189
DrugN,N-diethylphenylacetamide

HBB HBD

2.94e-049662CID000017076
DrugOP-2507

HBB HBD

2.94e-049662CID006438365
Drug3H-AMT

HBB HBD

2.94e-049662CID000107680
DrugAC1L252K

HBB HBD

2.94e-049662CID000015061
DrugZSTK474

MTOR PRKDC

2.94e-049662ctd:C510150
Drugsodium nitrite

KY HBB HBD

3.67e-0448663CID004517618
DrugN-(6-(6-chloro-5-(4-fluorophenylsulfonamido)pyridin-3-yl)benzo(d)thiazol-2-yl)acetamide

MTOR PRKDC

3.67e-0410662ctd:C558744
DrugHS 4

HBB HBD

3.67e-0410662CID005493398
Drugdecabromodiphenyl

HBB HBD

3.67e-0410662CID000026164
Drugferrous succinate

HBB HBD

3.67e-0410662CID000159252
Drug1-butyl-3-methylimidazolium hexafluorophosphate

HBB HBD

3.67e-0410662CID002734174
DrugAC1LADZE

HBB HBD

3.67e-0410662CID000486298
Drughexabromobenzene

HBB HBD

3.67e-0410662CID000006905
DiseaseDelta-Beta Thalassemia

HBB HBD

1.39e-053642C0271985
Diseasebeta thalassemia (implicated_via_orthology)

HBB HBD

1.39e-053642DOID:12241 (implicated_via_orthology)
Diseasehemoglobin measurement, hemoglobin A2 measurement

HBD HBD

4.61e-055642EFO_0004509, EFO_0005845
DiseaseChloracne

AHNAK HBB HBD

5.07e-0533643C0263454
DiseaseAdenoid Cystic Carcinoma

KANSL1 VCAN PRKDC MYBL1

6.75e-05100644C0010606
Diseasehemoglobin E disease

HBD HBD

6.91e-056642MONDO_0016243
Diseaseanemia (biomarker_via_orthology)

HBB HBD

9.66e-057642DOID:2355 (biomarker_via_orthology)
DiseaseMetastatic melanoma

MTOR PRKDC MAP3K13

2.23e-0454643C0278883
Diseaseneutrophil count, mean platelet volume, leukocyte count, erythrocyte count, mean corpuscular hemoglobin concentration, mean corpuscular volume, monocyte count, obsolete_red blood cell distribution width, basophil count, platelet count, eosinophil count

ANKRD26 HBB

2.52e-0411642EFO_0004305, EFO_0004308, EFO_0004309, EFO_0004526, EFO_0004528, EFO_0004584, EFO_0004833, EFO_0004842, EFO_0005090, EFO_0005091, EFO_0005192
Diseaseautosomal recessive polycystic kidney disease (implicated_via_orthology)

MTOR PKHD1

5.45e-0416642DOID:0110861 (implicated_via_orthology)
Diseasebrain cancer (implicated_via_orthology)

L3MBTL1 L3MBTL3

1.46e-0326642DOID:1319 (implicated_via_orthology)
Diseaseamyotrophic lateral sclerosis (implicated_via_orthology)

EWSR1 EPG5

1.94e-0330642DOID:332 (implicated_via_orthology)

Protein segments in the cluster

PeptideGeneStartEntry
TFLDIPLHEKKMTPG

ALG11

286

Q2TAA5
PMIHIYLDKETGKPK

EWSR1

396

Q01844
FHPLLKAVKAGMPIG

EPG5

1006

Q9HCE0
PIKKEESTKHFPKGM

VCAN

2226

P13611
GILIKGGKPLEMAHK

ATP7B

1006

P35670
HGKIKFPTMKVPKFG

AHNAK

301

Q09666
SMPDVDLHLKGPKVK

AHNAK

1196

Q09666
ISIPDVGLHLKGPKM

AHNAK

1451

Q09666
SMPDVDLHLKGPKVK

AHNAK

1856

Q09666
KISMPDVDLHLKGPK

AHNAK

1921

Q09666
MPDVDLHLKGPKVKG

AHNAK

1991

Q09666
KISMPDVDLHLKGPK

AHNAK

2116

Q09666
APKISMPDFDLHLKG

AHNAK

2576

Q09666
MPDFDLHLKGPKVKG

AHNAK

2581

Q09666
GKFKGPKFKIPEMHL

AHNAK

3726

Q09666
ISMPDFDLHLKGPKV

AHNAK

4001

Q09666
KISMPDFDLHLKGPK

AHNAK

4256

Q09666
APKISMPDFDLHLKG

AHNAK

4456

Q09666
MPDFDLHLKGPKVKG

AHNAK

4461

Q09666
LKGPKFKMPDLHLKA

AHNAK

4576

Q09666
KPSHKSLANPGLMKE

ANKRD26

346

Q9UPS8
HPPAVKAGGMRISKK

DAPL1

16

A0PJW8
GHMGKLVPLKETIKG

ATP5F1B

476

P06576
GPLFIHRTKGKGPLM

RASA4

571

O43374
GPLFIHRTKGKGPLM

RASA4B

571

C9J798
KGSPQMKGTPHFKEE

RIC1

111

Q4ADV7
PGSLKIKFRSGKFMP

ITPRIP

331

Q8IWB1
PPHGFQKKMKLEVVD

L3MBTL3

471

Q96JM7
ALSAKHKGKMPLRGP

MAK16

261

Q9BXY0
KVGPKMLDHEGKEVP

ISY1

101

Q9ULR0
PPTMGTHKLQIFAKG

KY

406

Q8NBH2
HDAGLKDPMKSKKQP

CCDC190

126

Q86UF4
ISKSAGAMLKPHAPK

ECPAS

1281

Q5VYK3
LHMPTSKENLKEKGP

PLRG1

56

O43660
FKLGMKLEGIDPQHP

L3MBTL1

306

Q9Y468
KKLSLKHRAPMPGSL

KANSL1

701

Q7Z3B3
KTGLKGIPEHLMGKL

KDM3B

831

Q7LBC6
KGPVPAIHKAGIMSA

HROB

211

Q8N3J3
ICKGLMTKHPGKRLG

PRKCB

571

P05771
KGVPHKSGMQTKRPD

MAP3K13

536

O43283
LFGPHMLKPTGKMKA

MTFR1

311

Q15390
TIKGAGHMVPTDKPL

CTSA

451

P10619
LPKMKAGGHKVLIFS

CHD9

1191

Q3L8U1
IGRMLLNDSKKGPPH

DOCK3

296

Q8IZD9
KLKNKASMTPGLHPG

GABRG1

371

Q8N1C3
PHGDTAKKPIIGILM

GGH

26

Q92820
PMTLHLPGSVVTKKG

FRMPD2

321

Q68DX3
IKEMKPPLRGHGKGA

GALNT5

71

Q7Z7M9
AGPFSHMIKLKTKPL

FNDC3A

936

Q9Y2H6
LPGKKGHCLVKGITM

ECM2

96

O94769
HPKYFKKVPGEGMPL

DNAJB13

266

P59910
MKPGKELKVLSYPAH

ERAP2

131

Q6P179
MGNPKVKAHGKKVLG

HBD

56

P02042
MGNPKVKAHGKKVLG

HBB

56

P68871
MKTRGLPKAKSHAPE

F10

466

P00742
GVKLEGKVPMHKLFL

ESRRA

401

P11474
IRDPGKKPVMLFLHG

NLGN2

171

Q8NFZ4
GGNMALKHTPLKTLP

MYBL1

471

P10243
KDLMGFGTKPRHITP

MTOR

301

P42345
AAPNPHSKGVLMFKK

SYNPO2L

286

Q9H987
HTKEALTKMEPPKKG

PHF2

551

O75151
HVGKPLLKKPMGPAH

FAM98A

186

Q8NCA5
HKRKFMKIGVSPPAK

PRSS23

256

O95084
LHIKGGKLIFMAPGP

PKHD1

1966

P08F94
ITHGPPEKKMGIKAS

ACADVL

291

P49748
GPKVHLPKVEMPSFK

AHNAK2

911

Q8IVF2
GLKGHLPKVEMPSFK

AHNAK2

1076

Q8IVF2
GFKGHLPKVQMPSLK

AHNAK2

1241

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

1406

Q8IVF2
GLKGHLPKVQMPSFK

AHNAK2

1571

Q8IVF2
GFKGHLPKVQMPSLK

AHNAK2

1736

Q8IVF2
GLKGHLPKVDMPSFK

AHNAK2

1901

Q8IVF2
GLKGHLPKVEMPSLK

AHNAK2

2066

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

2231

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

2396

Q8IVF2
GLKGHLPKVQMPSFK

AHNAK2

2561

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

2726

Q8IVF2
GLKGHLPKVQMPSFK

AHNAK2

2891

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

3056

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

3221

Q8IVF2
GLKGHLPKVEMPSFK

AHNAK2

3386

Q8IVF2
GLKGHLPKVEMPSLK

AHNAK2

3551

Q8IVF2
GLKGHLPKVQMPSFK

AHNAK2

3881

Q8IVF2
SLKGHLPKVQMPSFK

AHNAK2

4046

Q8IVF2
GLKGHLPKLQMPSFK

AHNAK2

4376

Q8IVF2
GLKGHLPKVEMPSFK

AHNAK2

4541

Q8IVF2
HEGKGSPLKMPKIKL

AHNAK2

4946

Q8IVF2
TGIFLDLMHLKKPGG

XRCC6

196

P12956
MHPGEKPLGVNKVAK

ZBTB21

691

Q9ULJ3
KILPKAEHFKMPEAG

XAGE2

91

Q96GT9
HAPGMKKIKLDTPEE

NUFIP1

221

Q9UHK0
FKRPHMTAKDLGLPG

TEX37

71

Q96LM6
KMLPKHLQGGKFPPT

SPATA31D1

1561

Q6ZQQ2
HGMKPRKAFPVLGID

SLC9A1

81

P19634
PKEMVPLGDSHSLKK

TEX13C

741

A0A0J9YWL9
TPGHLVKGKGQKTKM

TRBV23-1

26

A0A0A0MS06
MKFLHGKLGNPIVPL

PRKDC

2126

P78527
PGRPKKKHTGMASID

ZSWIM8

1131

A7E2V4
HSQPAKLVMVKKEGP

ZGRF1

1351

Q86YA3
GGLHCKPAKALPKEM

UGT2A3

276

Q6UWM9
AGKFKVLEPPMLGHD

TGM6

496

O95932
QKEKLPGKMSPKHDG

ZNF805

146

Q5CZA5
MKVHASKLGPLRAPG

ZNF219

321

Q9P2Y4
GMGPIGVKKHLAPFL

GLDC

766

P23378