Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	voltage-gated sodium channel activity	SCN11A TPCN2 SCN4A	2.02e-05	26	41	3	GO:0005248
GeneOntologyMolecularFunction	sodium channel activity	SCN11A TPCN2 SCN4A	1.66e-04	52	41	3	GO:0005272
GeneOntologyMolecularFunction	cytidine deaminase activity	APOBEC3B APOBEC3F	3.16e-04	13	41	2	GO:0004126
GeneOntologyMolecularFunction	glycerophospholipid flippase activity	ATP8B1 ABCA4	3.69e-04	14	41	2	GO:0140333
GeneOntologyMolecularFunction	sodium ion transmembrane transporter activity	SCN11A TPCN2 SCN4A SLC6A20	4.11e-04	171	41	4	GO:0015081
GeneOntologyMolecularFunction	phospholipid transporter activity	ATP8B1 ABCA4 OSBPL2	4.71e-04	74	41	3	GO:0005548
GeneOntologyMolecularFunction	flippase activity	ATP8B1 ABCA4	5.49e-04	17	41	2	GO:0140327
GeneOntologyMolecularFunction	minus-end-directed microtubule motor activity	DNAH10 DNAH6	6.16e-04	18	41	2	GO:0008569
GeneOntologyMolecularFunction	dynein light intermediate chain binding	DNAH10 DNAH6	1.50e-03	28	41	2	GO:0051959
GeneOntologyMolecularFunction	ATPase-coupled intramembrane lipid transporter activity	ATP8B1 ABCA4	1.50e-03	28	41	2	GO:0140326
GeneOntologyMolecularFunction	metalloendopeptidase activity	MMP21 CLCA4 TRABD2B	1.91e-03	120	41	3	GO:0004222
GeneOntologyMolecularFunction	deaminase activity	APOBEC3B APOBEC3F	2.21e-03	34	41	2	GO:0019239
GeneOntologyMolecularFunction	Wnt-protein binding	TRABD2B WIF1	2.21e-03	34	41	2	GO:0017147
GeneOntologyMolecularFunction	hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amidines	APOBEC3B APOBEC3F	2.48e-03	36	41	2	GO:0016814
GeneOntologyMolecularFunction	dynein intermediate chain binding	DNAH10 DNAH6	2.62e-03	37	41	2	GO:0045505
GeneOntologyMolecularFunction	carboxylic ester hydrolase activity	BCHE LIPN IARS2	4.08e-03	157	41	3	GO:0052689
GeneOntologyMolecularFunction	transporter activity	SCN11A CLCA4 ATP8B1 ABCA4 TPCN2 OSBPL2 SCN4A SLC6A20	4.17e-03	1289	41	8	GO:0005215
GeneOntologyMolecularFunction	intramembrane lipid transporter activity	ATP8B1 ABCA4	4.92e-03	51	41	2	GO:0140303
GeneOntologyBiologicalProcess	clearance of foreign intracellular DNA	APOBEC3B APOBEC3F	5.20e-05	6	39	2	GO:0044355
GeneOntologyBiologicalProcess	clearance of foreign intracellular nucleic acids	APOBEC3B APOBEC3F	5.20e-05	6	39	2	GO:0099046
GeneOntologyBiologicalProcess	DNA cytosine deamination	APOBEC3B APOBEC3F	1.55e-04	10	39	2	GO:0070383
GeneOntologyBiologicalProcess	cytidine to uridine editing	APOBEC3B APOBEC3F	2.27e-04	12	39	2	GO:0016554
GeneOntologyBiologicalProcess	cytidine metabolic process	APOBEC3B APOBEC3F	3.12e-04	14	39	2	GO:0046087
GeneOntologyBiologicalProcess	cytidine catabolic process	APOBEC3B APOBEC3F	3.12e-04	14	39	2	GO:0006216
GeneOntologyBiologicalProcess	cytidine deamination	APOBEC3B APOBEC3F	3.12e-04	14	39	2	GO:0009972
GeneOntologyBiologicalProcess	DNA deamination	APOBEC3B APOBEC3F	3.12e-04	14	39	2	GO:0045006
GeneOntologyBiologicalProcess	negative regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	4.11e-04	16	39	2	GO:0045869
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside metabolic process	APOBEC3B APOBEC3F	4.11e-04	16	39	2	GO:0046131
GeneOntologyBiologicalProcess	pyrimidine ribonucleoside catabolic process	APOBEC3B APOBEC3F	4.11e-04	16	39	2	GO:0046133
GeneOntologyBiologicalProcess	apical protein localization	CELSR1 ATP8B1	4.65e-04	17	39	2	GO:0045176
GeneOntologyBiologicalProcess	pyrimidine nucleoside catabolic process	APOBEC3B APOBEC3F	5.23e-04	18	39	2	GO:0046135
GeneOntologyBiologicalProcess	regulation of single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	5.84e-04	19	39	2	GO:0045091
GeneOntologyBiologicalProcess	base conversion or substitution editing	APOBEC3B APOBEC3F	5.84e-04	19	39	2	GO:0016553
GeneOntologyBiologicalProcess	sodium ion transmembrane transport	SCN11A TPCN2 SCN4A SLC6A20	6.27e-04	208	39	4	GO:0035725
GeneOntologyBiologicalProcess	single stranded viral RNA replication via double stranded DNA intermediate	APOBEC3B APOBEC3F	6.48e-04	20	39	2	GO:0039692
GeneOntologyCellularComponent	inner dynein arm	DNAH10 DNAH6	1.67e-04	10	41	2	GO:0036156
GeneOntologyCellularComponent	voltage-gated sodium channel complex	SCN11A SCN4A	5.01e-04	17	41	2	GO:0001518
GeneOntologyCellularComponent	sperm head-tail coupling apparatus	CFAP47 GLIPR1L1	5.63e-04	18	41	2	GO:0120212
GeneOntologyCellularComponent	axonemal dynein complex	DNAH10 DNAH6	1.09e-03	25	41	2	GO:0005858
GeneOntologyCellularComponent	sodium channel complex	SCN11A SCN4A	1.47e-03	29	41	2	GO:0034706
Domain	Na_channel_asu	SCN11A SCN4A	2.09e-04	10	41	2	IPR001696
Domain	Na_trans_assoc	SCN11A SCN4A	2.09e-04	10	41	2	IPR010526
Domain	Allrgn_V5/Tpx1_CS	GLIPR1L1 CRISP3	2.09e-04	10	41	2	IPR018244
Domain	Na_trans_assoc	SCN11A SCN4A	2.09e-04	10	41	2	PF06512
Domain	CRISP_1	GLIPR1L1 CRISP3	2.55e-04	11	41	2	PS01009
Domain	CRISP_2	GLIPR1L1 CRISP3	2.55e-04	11	41	2	PS01010
Domain	Channel_four-helix_dom	SCN11A TPCN2 SCN4A	2.65e-04	57	41	3	IPR027359
Domain	-	SCN11A TPCN2 SCN4A	2.65e-04	57	41	3	1.20.120.350
Domain	APOBEC_N	APOBEC3B APOBEC3F	3.06e-04	12	41	2	PF08210
Domain	APOBEC_N	APOBEC3B APOBEC3F	3.06e-04	12	41	2	IPR013158
Domain	ATPase_dyneun-rel_AAA	DNAH10 DNAH6	4.21e-04	14	41	2	IPR011704
Domain	Dynein_heavy_chain_D4_dom	DNAH10 DNAH6	4.21e-04	14	41	2	IPR024317
Domain	Dynein_HC_stalk	DNAH10 DNAH6	4.21e-04	14	41	2	IPR024743
Domain	Dynein_heavy_dom-2	DNAH10 DNAH6	4.21e-04	14	41	2	IPR013602
Domain	DHC_N2	DNAH10 DNAH6	4.21e-04	14	41	2	PF08393
Domain	MT	DNAH10 DNAH6	4.21e-04	14	41	2	PF12777
Domain	AAA_8	DNAH10 DNAH6	4.21e-04	14	41	2	PF12780
Domain	APOBEC/CMP_deaminase_Zn-bd	APOBEC3B APOBEC3F	4.21e-04	14	41	2	IPR016192
Domain	AAA_5	DNAH10 DNAH6	4.21e-04	14	41	2	PF07728
Domain	DHC_fam	DNAH10 DNAH6	4.85e-04	15	41	2	IPR026983
Domain	-	GLIPR1L1 CRISP3	4.85e-04	15	41	2	3.40.33.10
Domain	Dynein_heavy_dom	DNAH10 DNAH6	4.85e-04	15	41	2	IPR004273
Domain	CAP	GLIPR1L1 CRISP3	4.85e-04	15	41	2	PF00188
Domain	CAP_domain	GLIPR1L1 CRISP3	4.85e-04	15	41	2	IPR014044
Domain	CYT_DCMP_DEAMINASES_2	APOBEC3B APOBEC3F	4.85e-04	15	41	2	PS51747
Domain	SCP	GLIPR1L1 CRISP3	4.85e-04	15	41	2	SM00198
Domain	Allrgn_V5/Tpx1	GLIPR1L1 CRISP3	4.85e-04	15	41	2	IPR001283
Domain	Dynein_heavy	DNAH10 DNAH6	4.85e-04	15	41	2	PF03028
Domain	CYT_DCMP_DEAMINASES_1	APOBEC3B APOBEC3F	6.26e-04	17	41	2	PS00903
Domain	CMP_dCMP_Zn-bd	APOBEC3B APOBEC3F	6.26e-04	17	41	2	IPR002125
Domain	Cytidine_deaminase-like	APOBEC3B APOBEC3F	6.26e-04	17	41	2	IPR016193
Domain	Ion_trans_dom	SCN11A TPCN2 SCN4A	1.99e-03	114	41	3	IPR005821
Domain	Ion_trans	SCN11A TPCN2 SCN4A	1.99e-03	114	41	3	PF00520
Domain	AAA+_ATPase	ABCA4 DNAH10 DNAH6	3.86e-03	144	41	3	IPR003593
Domain	AAA	ABCA4 DNAH10 DNAH6	3.86e-03	144	41	3	SM00382
Domain	Rossmann-like_a/b/a_fold	TRMU IARS2	4.01e-03	43	41	2	IPR014729
Domain	-	TRMU IARS2	4.01e-03	43	41	2	3.40.50.620
Domain	EGF_extracell	TENM4 WIF1	7.68e-03	60	41	2	IPR013111
Domain	EGF_2	TENM4 WIF1	7.68e-03	60	41	2	PF07974
Pathway	REACTOME_MRNA_EDITING_C_TO_U_CONVERSION	APOBEC3B APOBEC3F	1.04e-04	7	32	2	MM15412
Pathway	REACTOME_MRNA_EDITING	APOBEC3B APOBEC3F	1.78e-04	9	32	2	MM15445
Pubmed	Identification of predicted human outer dynein arm genes: candidates for primary ciliary dyskinesia genes.	DNAH10 DNAH6	1.36e-06	2	41	2	15937072
Pubmed	Murine Leukemia Virus P50 Protein Counteracts APOBEC3 by Blocking Its Packaging.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	32641479
Pubmed	APOBEC3 deletion increases the risk of breast cancer: a meta-analysis.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	27602762
Pubmed	Integrative genomic analysis implicates limited peripheral adipose storage capacity in the pathogenesis of human insulin resistance.	DNAH10 L3MBTL3	4.06e-06	3	41	2	27841877
Pubmed	Anti-Friend virus antibody is associated with recovery from viremia and loss of viral leukemia cell-surface antigens in leukemic mice. Identification of Rfv-3 as a gene locus influencing antibody production.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	286744
Pubmed	A novel role for APOBEC3: susceptibility to sexual transmission of murine acquired immunodeficiency virus (mAIDS) is aggravated in APOBEC3 deficient mice.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	22691411
Pubmed	Studies on the restriction of murine leukemia viruses by mouse APOBEC3.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	22666481
Pubmed	APOBEC3 deletion polymorphism is associated with epithelial ovarian cancer risk among Chinese women.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	24577894
Pubmed	Host restriction of murine gammaherpesvirus 68 replication by human APOBEC3 cytidine deaminases but not murine APOBEC3.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	24725948
Pubmed	APOBEC3B and APOBEC3F inhibit L1 retrotransposition by a DNA deamination-independent mechanism.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	16648136
Pubmed	Fv1 restriction and retrovirus vaccine immunity in Apobec3-deficient 129P2 mice.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	23533681
Pubmed	The glycosylated Gag protein of a murine leukemia virus inhibits the antiretroviral function of APOBEC3.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	20702647
Pubmed	Spontaneous recovery from Friend retrovirus-induced leukemia. Mapping of the Rfv-2 gene in the Q/TL region of mouse MHC.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	1541833
Pubmed	In Vivo Examination of Mouse APOBEC3- and Human APOBEC3A- and APOBEC3G-Mediated Restriction of Parvovirus and Herpesvirus Infection in Mouse Models.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	27356895
Pubmed	IFN-α treatment inhibits acute Friend retrovirus replication primarily through the antiviral effector molecule Apobec3.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	23315078
Pubmed	Persistent Friend virus replication and disease in Apobec3-deficient mice expressing functional B-cell-activating factor receptor.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	20980520
Pubmed	Requirement for Fc effector mechanisms in the APOBEC3/Rfv3-dependent neutralizing antibody response.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	25589647
Pubmed	Identification of a non-H-2 gene (Rfv-3) influencing recovery from viremia and leukemia induced by Friend virus complex.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	284359
Pubmed	Adaptive evolution of Mus Apobec3 includes retroviral insertion and positive selection at two clusters of residues flanking the substrate groove.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	20617165
Pubmed	Impact of Suboptimal APOBEC3G Neutralization on the Emergence of HIV Drug Resistance in Humanized Mice.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	31801862
Pubmed	Apobec-mediated retroviral hypermutation in vivo is dependent on mouse strain.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	39208378
Pubmed	Deamination hotspots among APOBEC3 family members are defined by both target site sequence context and ssDNA secondary structure.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	31943071
Pubmed	Murine leukemia virus glycosylated Gag blocks apolipoprotein B editing complex 3 and cytosolic sensor access to the reverse transcription complex.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	23671100
Pubmed	Structural perspectives on HIV-1 Vif and APOBEC3 restriction factor interactions.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	31518043
Pubmed	Innate retroviral restriction by Apobec3 promotes antibody affinity maturation in vivo.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	20566830
Pubmed	APOBEC-mediated viral restriction: not simply editing?	APOBEC3B APOBEC3F	4.06e-06	3	41	2	17303427
Pubmed	Chromosome mapping of Rfv3, a host resistance gene to Friend murine retrovirus.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	7884913
Pubmed	N-linked glycosylation protects gammaretroviruses against deamination by APOBEC3 proteins.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	25505062
Pubmed	Molecular analysis of γ1, γ3, and α class switch recombination junctions in APOBEC3-deficient mice using high-throughput sequencing.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	31595054
Pubmed	APOBEC3 signature mutations in chronic lymphocytic leukemia.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	24840555
Pubmed	Role of APOBEC3 in genetic diversity among endogenous murine leukemia viruses.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	17967065
Pubmed	Inhibition of xenotropic murine leukemia virus-related virus by APOBEC3 proteins and antiviral drugs.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	20335265
Pubmed	Deaminase-Dead Mouse APOBEC3 Is an In Vivo Retroviral Restriction Factor.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	29593034
Pubmed	Mouse APOBEC3 interferes with autocatalytic cleavage of murine leukemia virus Pr180gag-pol precursor and inhibits Pr65gag processing.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	31830125
Pubmed	Requirement for CD4(+) T cells in the Friend murine retrovirus neutralizing antibody response: evidence for functional T cells in genetic low-recovery mice.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	9765497
Pubmed	Noninfectious retrovirus particles drive the APOBEC3/Rfv3 dependent neutralizing antibody response.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	21998583
Pubmed	Biochemical and biological studies of mouse APOBEC3.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	24453360
Pubmed	Direct inhibition of human APOBEC3 deaminases by HIV-1 Vif independent of the proteolysis pathway.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	38115583
Pubmed	APOBEC3 inhibition of mouse mammary tumor virus infection: the role of cytidine deamination versus inhibition of reverse transcription.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	23449789
Pubmed	Effects of zidovudine on Friend virus complex infection in Rfv-3r/s genotype-containing mice used as a model for HIV infection.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	2157836
Pubmed	Distinctive High Expression of Antiretroviral APOBEC3 Protein in Mouse Germinal Center B Cells.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	35458563
Pubmed	Natural resistance to HIV infection: The Vif-APOBEC interaction.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	17067930
Pubmed	Two genetic determinants acquired late in Mus evolution regulate the inclusion of exon 5, which alters mouse APOBEC3 translation efficiency.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	22275865
Pubmed	APOBEC3-independent interferon-induced viral clearance in hepatitis B virus transgenic mice.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	18434399
Pubmed	Induction of APOBEC3 in vivo causes increased restriction of retrovirus infection.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	19153238
Pubmed	Apobec3 encodes Rfv3, a gene influencing neutralizing antibody control of retrovirus infection.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	18772436
Pubmed	Antibody-induced modulation of Friend virus cell surface antigens decreases virus production by persistent erythroleukemia cells: influence of the Rfv-3 gene.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	293683
Pubmed	Enhanced replication and pathogenesis of Moloney murine leukemia virus in mice defective in the murine APOBEC3 gene.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	19150103
Pubmed	Mouse APOBEC3 restricts friend leukemia virus infection and pathogenesis in vivo.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	18786991
Pubmed	Initial sequencing and comparative analysis of the mouse genome.	APOBEC3B APOBEC3F	4.06e-06	3	41	2	12466850
Pubmed	Immunoglobulin somatic hypermutation by APOBEC3/Rfv3 during retroviral infection.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	24821801
Pubmed	Small molecular compounds inhibit HIV-1 replication through specifically stabilizing APOBEC3G.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	20363737
Pubmed	Murine APOBEC1 is a powerful mutator of retroviral and cellular RNA in vitro and in vivo.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	18983852
Pubmed	Expression and subcellular localisation of AID and APOBEC3 in adenoid and palatine tonsils.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	29343743
Pubmed	APOBEC3 regulates keratinocyte differentiation and expression of Notch3.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	31400166
Pubmed	APOBEC3G cytidine deaminase inhibits retrotransposition of endogenous retroviruses.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	15674295
Pubmed	Virus-specific CD8+ T cells upregulate programmed death-1 expression during acute friend retrovirus infection but are highly cytotoxic and control virus replication.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	21873525
Pubmed	Ribonuclease L is not critical for innate restriction and adaptive immunity against Friend retrovirus infection.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	23725696
Pubmed	APOBEC3G promotes liver metastasis in an orthotopic mouse model of colorectal cancer and predicts human hepatic metastasis.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	21985787
Pubmed	APOBEC3A functions as a restriction factor of human papillomavirus.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	25355878
Pubmed	Human and murine APOBEC3s restrict replication of koala retrovirus by different mechanisms.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	26253512
Pubmed	APOBEC3 enzymes restrict marginal zone B cells.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	25501566
Pubmed	Restriction by APOBEC3 proteins of endogenous retroviruses with an extracellular life cycle: ex vivo effects and in vivo "traces" on the murine IAPE and human HERV-K elements.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	18702815
Pubmed	HIV-1 Vif versus the APOBEC3 cytidine deaminases: an intracellular duel between pathogen and host restriction factors.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	20538015
Pubmed	Reversed functional organization of mouse and human APOBEC3 cytidine deaminase domains.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	17020885
Pubmed	Persistence of viremia and production of neutralizing antibodies differentially regulated by polymorphic APOBEC3 and BAFF-R loci in friend virus-infected mice.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	20375169
Pubmed	APOBEC3 proteins expressed in mammary epithelial cells are packaged into retroviruses and can restrict transmission of milk-borne virions.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	21147467
Pubmed	Mice deficient in APOBEC2 and APOBEC3.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	16055735
Pubmed	The incorporation of APOBEC3 proteins into murine leukemia viruses.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	18572219
Pubmed	The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	38049664
Pubmed	Restriction of foamy viruses by APOBEC cytidine deaminases.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	16378963
Pubmed	Tetherin/BST-2 promotes dendritic cell activation and function during acute retrovirus infection.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	26846717
Pubmed	Vaccinia virus replication is not affected by APOBEC3 family members.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	17052331
Pubmed	Type I interferon signaling is required for the APOBEC3/Rfv3-dependent neutralizing antibody response but not innate retrovirus restriction.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	28415995
Pubmed	Immunity to retroviral infection: the Friend virus model.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	9223268
Pubmed	Species-specific restriction of apobec3-mediated hypermutation.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	18032489
Pubmed	Multifaceted HIV-1 Vif interactions with human E3 ubiquitin ligase and APOBEC3s.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	32893454
Pubmed	Reassessment of murine APOBEC1 as a retrovirus restriction factor in vivo.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	25303118
Pubmed	APOBEC3 inhibits mouse mammary tumour virus replication in vivo.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	17259974
Pubmed	Identification, tissue specific expression, and chromosomal localisation of several human dynein heavy chain genes.	DNAH10 DNAH6	8.12e-06	4	41	2	11175280
Pubmed	HIV restriction by APOBEC3 in humanized mice.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	23555255
Pubmed	The Cytidine Deaminase APOBEC3G Contributes to Cancer Mutagenesis and Clonal Evolution in Bladder Cancer.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	36480186
Pubmed	Ancient adaptive evolution of the primate antiviral DNA-editing enzyme APOBEC3G.	APOBEC3B APOBEC3F	8.12e-06	4	41	2	15269786
Pubmed	APOBEC3 inhibits DEAD-END function to regulate microRNA activity.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	23890083
Pubmed	Phosphorylation directly regulates the intrinsic DNA cytidine deaminase activity of activation-induced deaminase and APOBEC3G protein.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	21659520
Pubmed	HIV-1 Vif, APOBEC, and intrinsic immunity.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	18577210
Pubmed	Different modes of retrovirus restriction by human APOBEC3A and APOBEC3G in vivo.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	24851906
Pubmed	IFN-α and lipopolysaccharide upregulate APOBEC3 mRNA through different signaling pathways.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	22972924
Pubmed	The APOBEC3 cytidine deaminases: an innate defensive network opposing exogenous retroviruses and endogenous retroelements.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	18304004
Pubmed	Human immunodeficiency virus type 1 Vif functionally interacts with diverse APOBEC3 cytidine deaminases and moves with them between cytoplasmic sites of mRNA metabolism.	APOBEC3B APOBEC3F	1.35e-05	5	41	2	17977970
Pubmed	Mouse apolipoprotein B editing complex 3 (APOBEC3) is expressed in germ cells and interacts with dead-end (DND1).	APOBEC3B APOBEC3F	1.35e-05	5	41	2	18509452
Pubmed	SERINC5 Potently Restricts Retrovirus Infection In Vivo.	APOBEC3B APOBEC3F	2.03e-05	6	41	2	32665269
Pubmed	Retroelements versus APOBEC3 family members: No great escape from the magnificent seven.	APOBEC3B APOBEC3F	2.03e-05	6	41	2	22912627
Pubmed	APOBEC3 versus Retroviruses, Immunity versus Invasion: Clash of the Titans.	APOBEC3B APOBEC3F	2.03e-05	6	41	2	22720156
Pubmed	APOBEC3 proteins mediate the clearance of foreign DNA from human cells.	APOBEC3B APOBEC3F	2.84e-05	7	41	2	20062055
Pubmed	An anthropoid-specific locus of orphan C to U RNA-editing enzymes on chromosome 22.	APOBEC3B APOBEC3F	2.84e-05	7	41	2	11863358
Pubmed	APOBEC3A is a potent inhibitor of adeno-associated virus and retrotransposons.	APOBEC3B APOBEC3F	2.84e-05	7	41	2	16527742
Pubmed	DDX41 Recognizes RNA/DNA Retroviral Reverse Transcripts and Is Critical for In Vivo Control of Murine Leukemia Virus Infection.	APOBEC3B APOBEC3F	2.84e-05	7	41	2	29871919
Pubmed	Human and rhesus APOBEC3D, APOBEC3F, APOBEC3G, and APOBEC3H demonstrate a conserved capacity to restrict Vif-deficient HIV-1.	APOBEC3B APOBEC3F	2.84e-05	7	41	2	21835787
Pubmed	Enriching the Housing Environment for Mice Enhances Their NK Cell Antitumor Immunity via Sympathetic Nerve-Dependent Regulation of NKG2D and CCR5.	KLRK1 LYST	3.78e-05	8	41	2	28082402
Cytoband	20q13.3	PPP1R3D OSBPL2	1.46e-04	20	41	2	20q13.3
Cytoband	Ensembl 112 genes in cytogenetic band chr22q13	TRMU CELSR1 APOBEC3B APOBEC3F	2.15e-04	330	41	4	chr22q13
Cytoband	Ensembl 112 genes in cytogenetic band chr1p22	CLCA4 ABCA4	6.72e-03	137	41	2	chr1p22
GeneFamily	Sodium voltage-gated channel alpha subunits	SCN11A SCN4A	9.51e-05	9	30	2	1203
GeneFamily	Apolipoprotein B mRNA editing enzyme catalytic subunits	APOBEC3B APOBEC3F	1.74e-04	12	30	2	406
GeneFamily	Dyneins, axonemal	DNAH10 DNAH6	3.56e-04	17	30	2	536
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPCN2 TENM4 DNAH10 SIPA1L1	1.51e-05	163	41	4	8dc0128eeede933537e3bcc5d6ec0322711552f3
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid-Kupffer_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPCN2 TENM4 DNAH10 SIPA1L1	1.51e-05	163	41	4	fd243ca223079033be480a24817a399f281fa4d4
ToppCell	wk_20-22-Mesenchymal-Chondrocyte-Resting_chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	TRABD2B TENM4 POLA1 WIF1	2.33e-05	182	41	4	03a5a02acd48f0eb210485348bfe0cd21f486215
ToppCell	3'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.3\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DNAH6 WIF1	2.94e-05	193	41	4	bdb7401dd9059032f930f2b575f2ef8e504b6594
ToppCell	NS-moderate-d_0-4\|moderate / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	CFAP47 CELSR1 DNAH10 DNAH6	2.94e-05	193	41	4	ea345d34440b25f65358a53dc72831998d1c3620
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	CFAP47 CELSR1 DNAH10 DNAH6	3.12e-05	196	41	4	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	ABCA4 DNAH6 JMJD8 POLR1C	3.18e-05	197	41	4	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	wk_20-22-Epithelial\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	CELSR1 DNAH10 DNAH6 WIF1	3.18e-05	197	41	4	468071c1911cdf8e8806a78dbceb95379e28ae91
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-6m-Mesenchymal-Cilia-bearing_cell\|6m / Sample Type, Dataset, Time_group, and Cell type.	ABCA4 DNAH6 SLC6A20 WIF1	3.37e-05	200	41	4	177f9ad8dd8635394c575a2b30140184df0bd51e
ToppCell	VE-CD4-CD8_2\|VE / Condition, Cell_class and T cell subcluster	KLRK1 SCN11A ALOX12B	1.92e-04	122	41	3	6745035feaf807b6a6b9537ac9d5ee0e000196eb
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABCA4 TPCN2 SLC6A20	2.59e-04	135	41	3	4cb399620aa9edc2ca59e4df76ab7011ceb58db9
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABCA4 TPCN2 SLC6A20	2.59e-04	135	41	3	6bd2a0bfd8d20950f1b66810668682dc055a0ada
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABCA4 TPCN2 SLC6A20	2.59e-04	135	41	3	7e3559ed0fef7916d1938b4e1a9fa4456a60e3d3
ToppCell	Hippocampus-Endothelial-ENDOTHELIAL_TIP-Dcn_2-Dcn_2_1-Endothelial_Tip.Dcn.Agt_(Agt)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	ABCA4 TPCN2 SLC6A20	2.59e-04	135	41	3	97989546826bf3739e1b86a10832a457fd37c5d2
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L5_PT-L5_PT_VISp_C1ql2_Cdh13\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LIPN ATP8B1 ALOX12B	2.65e-04	136	41	3	1f3000d5f105c87c80f8ae1dd2264bcd7f757a9c
ToppCell	Control-Epithelial_alveolar-AT_1-Differentiating_AT2\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	CELSR1 ABCA4 HSD11B1L	2.76e-04	138	41	3	611fe0fb284e12678f9c47a0bdbfc367a93c52b3
ToppCell	PND07-28-samps-Mesenchymal-Myofibroblast-MyoFB-3\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	MMP21 CLCA4 TRABD2B	2.94e-04	141	41	3	7ae8ead02e5aeb4106c4a30c08a7a061da3a5d6a
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPCN2 GRINA LYST	3.39e-04	148	41	3	ba277c898678dd36f8dc1d681301c71901b89055
ToppCell	facs-Marrow-T-cells-3m-Myeloid-granulocyte\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TPCN2 GRINA LYST	3.39e-04	148	41	3	b4632029ebd14969bda59a1bd1454eadb8efe563
ToppCell	COVID-19-Epithelial_cells-Airway_mucous\|COVID-19 / group, cell type (main and fine annotations)	CFAP47 DNAH10 DNAH6	3.60e-04	151	41	3	8216462e723fec2797387929dde095370947e10a
ToppCell	facs-Trachea-24m-Hematologic-myeloid-granulocyte-granulocyte_l8\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R3D GRINA LYST	3.74e-04	153	41	3	338684d420b01e32918fa19048ccdda234942ce1
ToppCell	Severe-B_naive-5\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PPP1R3D DNAH10 LYST	3.74e-04	153	41	3	44572f87d403e314050ab935d2cd676c33d9c287
ToppCell	10x5'-bone_marrow-Lymphocytic_T_CD8-Trm_gut_CD8\|bone_marrow / Manually curated celltypes from each tissue	KLRK1 MMP21 CRISP3	3.81e-04	154	41	3	93145a1bc5712ae664690b03a9e00ce1f92cfc7e
ToppCell	facs-Marrow-KLS-18m-Myeloid-CD4+_macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 TRABD2B TPCN2	4.03e-04	157	41	3	5d08ff0ba9d3df9cc30f13cab2d2b395ea6f3446
ToppCell	droplet-Liver-Hepatocytes-24m-Myeloid\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 DNAH10 SIPA1L1	4.03e-04	157	41	3	ec433d2fe827abdb647be4176c231b7052482b6f
ToppCell	facs-Marrow-KLS-18m-Myeloid-macrophage\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 TRABD2B TPCN2	4.03e-04	157	41	3	ad9c9b7dfeee3ae46e7e593c51a0407df12195b4
ToppCell	Severe-B_naive-5\|Severe / disease group and sub_cluster of B and Plasma cells(res = 0.5)	PPP1R3D DNAH10 LYST	4.03e-04	157	41	3	a57ee4a6febdff3ee3d1645836695e6e7c055cf8
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D GRINA LYST	4.11e-04	158	41	3	d43b335e6aa12d84a75b988fbd6127ff1f4af25c
ToppCell	facs-Lung-ENDOMUCIN-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D GRINA LYST	4.11e-04	158	41	3	ab12b29ce51ca2fcac469cc932391217d97145f9
ToppCell	facs-Lung-EPCAM-18m-Myeloid-neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D GRINA LYST	4.18e-04	159	41	3	baf843dc44b072504eb1d28de55b1ee67aeec32b
ToppCell	facs-Lung-EPCAM-18m-Myeloid-Neutrophil\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D GRINA LYST	4.18e-04	159	41	3	9eb78202b9a4e8217f00e64d5142ed28c00abd04
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD8_c01-LEF1\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SCN11A DNAH10 APOBEC3B	4.18e-04	159	41	3	2233fee5dcdb6c7dee5b1bd8efbc07d86b339927
ToppCell	facs-Lung-nan-3m-Endothelial-Capillary_Type_1_Cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TENM4 DNAH10 SCN4A	4.26e-04	160	41	3	f2cdee5a9e3b0eb125d6be7b5d239eb04333ae41
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell-D032\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRISP3 CELSR1 ATP8B1	4.34e-04	161	41	3	2d63b279d9a5132e1c09b03930bf9039036d24a2
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c06-TNF\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	KLRK1 BCHE LYST	4.34e-04	161	41	3	a480107b1c7773f2081afca2657e0b7fc88a5645
ToppCell	PND07-Endothelial-Endothelial_lymphatic\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A CLCA4 CELSR1	4.34e-04	161	41	3	133b4fadb499e842c19f573f9cf09ce08c1d4813
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A CLCA4 CELSR1	4.34e-04	161	41	3	cb177ca10d848d0e25399ab5ebfcde1071fb94c2
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A CLCA4 CELSR1	4.34e-04	161	41	3	9466b8658244116f8d21f2f88fb8c2d184b1bdf2
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R3D GRINA LYST	4.42e-04	162	41	3	4e7e565091bce227d794a36af2e5dfc4a791efad
ToppCell	facs-Lung-18m-Hematologic-myeloid-neutrophil\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	PPP1R3D GRINA LYST	4.42e-04	162	41	3	ad974426039f4952c59d27167eac24dc6ce63f5e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCA4 TRABD2B MBOAT1	4.42e-04	162	41	3	285e6d553f485fd9f1075c4e1b940da251b5ea35
ToppCell	PND07-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	SCN11A CLCA4 CELSR1	4.42e-04	162	41	3	96c6e94a10b124a1d25dcd705ec5aaa8609c1089
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK_cell\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 L3MBTL3 LYST	4.58e-04	164	41	3	950f87d9dacee45c9004a9bf894543de38f72ee5
ToppCell	droplet-Liver-nan-3m-Lymphocytic\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 L3MBTL3 LYST	4.58e-04	164	41	3	bf0d3ad9016a0b8011a2385bb92f0a4f5edad1d6
ToppCell	droplet-Liver-nan-3m-Lymphocytic-NK/T\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KLRK1 L3MBTL3 LYST	4.58e-04	164	41	3	c33910a6d87580902e9e7bd27afe6ea63b5eff8d
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B1 RTL1 WIF1	4.66e-04	165	41	3	c746bb22ef52d7f7fa6ee9c37ae6bbe0ccce718e
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 CELSR1 DNAH6	4.66e-04	165	41	3	82530f96aaefe28a13bad0474bbad043f127a86c
ToppCell	facs-Kidney-nan-24m-Mesenchymal-mesangial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ATP8B1 RTL1 WIF1	4.66e-04	165	41	3	4cdd80580d5638fd649280ba3893251c2f898f3f
ToppCell	PCW_07-8.5-Epithelial-Epithelial_ciliated-epi_ciliated_(14)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	CFAP47 CELSR1 DNAH6	4.66e-04	165	41	3	0c714e852f912b5749de4cb0895406673979b2e6
ToppCell	343B-Lymphocytic-ILC\|343B / Donor, Lineage, Cell class and subclass (all cells)	TRMU ATP8B1 L3MBTL3	4.74e-04	166	41	3	a54377c703efff42d2cc1a8fdb610facc58053dd
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L3-5_THEMIS_UBE2F\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	GLIPR1L1 ARSJ DNAH6	4.91e-04	168	41	3	bfa1491e8d433933003778b274710d3a16d973cb
ToppCell	facs-BAT-Fat-18m-Myeloid-granulocyte\|BAT / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PPP1R3D GRINA LYST	5.00e-04	169	41	3	d3e6c75e5eda133fb6535cfe6c6a1026641f26ac
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CFAP47 DNAH10 DNAH6	5.00e-04	169	41	3	fba841664939c771881ba97f14ef1df6635c04ff
ToppCell	wk_20-22-Mesenchymal-Chondrocyte\|wk_20-22 / Celltypes from embryonic and fetal-stage human lung	SCN11A TENM4 WIF1	5.17e-04	171	41	3	d2938639e9a7c349e5a6ec61724222f9d127c89f
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCHE MBOAT1 DNAH6	5.17e-04	171	41	3	5447b78148f7bccb727e2fc108589b2af02a5d31
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cel\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCHE MBOAT1 DNAH6	5.26e-04	172	41	3	a7eee0a30d2fe20c865a07b9004c6a821a72c0c4
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRINA MBOAT1 LYST	5.26e-04	172	41	3	c05af6e559f6af0fb15cefa03ffa1413e98a1a4a
ToppCell	droplet-Pancreas-Exocrine-18m-Epithelial-pancreatic_ductal_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BCHE MBOAT1 DNAH6	5.26e-04	172	41	3	0a9fe2cd28203970295a1288078c66eadac1c9ed
ToppCell	PND10-Immune-Immune_Myeloid-Granulocytic-Basophil\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	GRINA MBOAT1 LYST	5.26e-04	172	41	3	953b05f776348cff784e79c93df65841939d880f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal-Inh_GABAergic-i_Gaba_2-GABA_PAX6-Inh_L1-3_PAX6_NABP1\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFAP47 BCHE WIF1	5.26e-04	172	41	3	4ae0a3ba4660fc9292b7e9a3087a25a3349d8965
ToppCell	TCGA-Head_and_Esophagus-Solid_Tissue_Normal-Head_and_Neck-Head_and_Neck_normal_tissue-5\|TCGA-Head_and_Esophagus / Sample_Type by Project: Shred V9	CRISP3 CLCA4 DNAH10	5.26e-04	172	41	3	6b8a8d3b97c10b9d092307eed3cacbd2745df185
ToppCell	Children_(3_yrs)-Mesenchymal-myofibroblast_cell-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	BCHE TRABD2B TENM4	5.35e-04	173	41	3	1f16d47f5548e257e4b17f8070c5619780a9c5fd
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM4 ARSJ DNAH6	5.35e-04	173	41	3	ee972d9cc68755926512fd3bbe1267098c67cd94
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar-Ciliated_cell_of_lung_parenchyma\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 DNAH10 DNAH6	5.44e-04	174	41	3	f41d05a3703d7092bd3c4a97c15ae13069aaa4ad
ToppCell	PND07-Endothelial-Endothelial_blood-vessel-Macrovascular_EC-VEC-VEC_G2M\|PND07 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PPP1R3D ARSJ POLA1	5.44e-04	174	41	3	6c36d607c48267a75ab4da6fb2fe3f931d1b3b52
ToppCell	PND07-28-samps-Epithelial-Epithelial-non_alveolar\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	CFAP47 DNAH10 DNAH6	5.53e-04	175	41	3	c01a15b2084da4a18f8ff3623f44eb9dfe499f10
ToppCell	droplet-Heart-HEART_(LV+RV_ONLY)-30m-Endothelial-leukocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CELSR1 DNAH10 DNAH6	5.53e-04	175	41	3	f6e1d7297a4dbb38e1ab4f738d91f0e62abaee69
ToppCell	Ciliated_cells-A-Donor_02\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 DNAH10 DNAH6	5.62e-04	176	41	3	1c364155f46b9a7c995bdc2cc2333c437cd90f5b
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFAP47 BCHE WIF1	5.72e-04	177	41	3	2b675840b7d2bb536c2c600936733bd9e97e7120
ToppCell	facs-Trachea-24m-Mesenchymal-myofibroblast-tracheobronchial_smooth_muscle_cell-smooth_muscle_cell_of_trachea_l6-17\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	BCHE DNAH10 RTL1	5.72e-04	177	41	3	8abdf1d970b2f15e17e185f3e612dd5065c88757
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Inh_GABAergic-i_Gaba_3-GABA_PVALB_1-Inh_L6_LHX6_GLP1R\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	CFAP47 BCHE WIF1	5.72e-04	177	41	3	5e0fca9bd5e5ffe6d39f5bcd81f36512f3b0cb1b
ToppCell	5'-Parenchyma_lung-Epithelial-Airway_ciliated-ciliated_columnar_cell_of_tracheobronchial_tree-Multiciliated_(non-nasal)-Multiciliated_(non-nasal)_L.0.3.2.1\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CELSR1 DNAH10 DNAH6	5.72e-04	177	41	3	aef050784abbba45c4ab4e8328339c8739c5c453
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell-ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 DNAH10 DNAH6	5.72e-04	177	41	3	3cfde67b93f3986312f5e74e42504214d966e7dc
ToppCell	facs-Trachea-3m-Epithelial-airway_epithelial-tracheobronchial_ciliated_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	CFAP47 DNAH10 DNAH6	5.72e-04	177	41	3	12a52a12a87a31e501ced611f46a90d172ca7e35
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D062\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 DNAH10 DNAH6	5.81e-04	178	41	3	de5d50d7ca9ee9eb62f50c88a0c6d47f0694b2e6
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM4 ARSJ DNAH6	5.91e-04	179	41	3	b35a7f8115c997c390201da01d7cb10b10769aec
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 ARSJ DNAH6	6.00e-04	180	41	3	b7513b9816a9cb9f3caaddb2a9fed0be1c7f9805
ToppCell	Ciliated_cells-B-Donor_06\|World / lung cells shred on cell class, cell subclass, sample id	CFAP47 DNAH10 DNAH6	6.00e-04	180	41	3	bdea5ec6b60fc8c7cce4d71db5da74ac8675e211
ToppCell	Primary_Visual_cortex_(V1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4\|Primary_Visual_cortex_(V1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	ABCA4 ARSJ DNAH6	6.00e-04	180	41	3	f96c5be4705e3d338c0393d2885ac8d5beccd6fd
ToppCell	TCGA-Colorectal-Solid_Tissue_Normal\|TCGA-Colorectal / Sample_Type by Project: Shred V9	BCHE SCN11A CLCA4	6.10e-04	181	41	3	88f6f56f5f58b479d5db91b32c45934c045f88ea
ToppCell	Fetal_29-31_weeks-Epithelial-ciliated_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	CFAP47 DNAH10 DNAH6	6.10e-04	181	41	3	dfce05bd472f67e6e2bb60ebd6fd34f0a9aeeca6
ToppCell	Adult-Epithelial-ciliated_cell-D122\|Adult / Lineage, Cell type, age group and donor	CFAP47 DNAH10 DNAH6	6.20e-04	182	41	3	7ded554a4b441e6496db673ba206c0d76ccad7d9
ToppCell	Control-Epithelial_cells-Airway_ciliated\|Control / group, cell type (main and fine annotations)	CFAP47 DNAH10 DNAH6	6.20e-04	182	41	3	fb725d10d9ed25dfc6d5bb69cfef78513f7d3e8f
ToppCell	Fetal_29-31_weeks-Mesenchymal-myofibroblast_cell-D088\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	BCHE TRABD2B TENM4	6.20e-04	182	41	3	ed6ae0fd8653f213fe29906a6a4e0729a62e1b75
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 TENM4 ALOX12B	6.20e-04	182	41	3	b8be66a867ea1bbae0820b26dbd55b68611f5ad5
ToppCell	Children_(3_yrs)-Epithelial-lung_goblet_cell\|Children_(3_yrs) / Lineage, Cell type, age group and donor	CRISP3 CELSR1 ATP8B1	6.20e-04	182	41	3	3f1a666fe27dd7529c114539ed5f6b8ca585c875
ToppCell	wk_15-18-Epithelial-Proximal_epithelial-Deuterosomal\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	CFAP47 DNAH10 DNAH6	6.20e-04	182	41	3	000eca5baa6eb2335a1e6d76a13fff5382b0e150
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_connecting_tubule_epithelial_cell-Connecting_Tubule_Principal_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ATP8B1 ARSJ MBOAT1	6.20e-04	182	41	3	f96095b81188b52db8fcfca4837129cfcd9bd7b7
ToppCell	facs-Kidney-nan-24m-Epithelial-kidney_loop_of_Henle_ascending_limb_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLCA4 TENM4 ALOX12B	6.20e-04	182	41	3	cb488f9a9b200e2557335ccf22535cd247512cdc
ToppCell	Control-Stromal_mesenchymal-Lung_smooth_muscle-MatrixFB_->_Myofibroblast\|Control / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	TRABD2B TENM4 WIF1	6.30e-04	183	41	3	7eae9b3b4d1c9b135fa7cff348393d4adec474b4
ToppCell	PCW_05-06-Epithelial-Epithelial_airway-epi_proximal_progenitor1_(6)\|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung	CFAP47 CELSR1 WIF1	6.30e-04	183	41	3	c5b10571599dc26476170b54b53f09c23e6b3117
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 TENM4 DNAH10	6.40e-04	184	41	3	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPP1R3D MBOAT1 DNAH10	6.40e-04	184	41	3	a8c6028d745aaa6ee7842259238694cb50ce0526
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil-Neu_4\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	PPP1R3D MBOAT1 DNAH10	6.40e-04	184	41	3	081d045f3bc98a36f342de7d50f39c9a888dd7eb
ToppCell	Control-Myeloid_G-immature_Neutrophil\|Control / Disease group, lineage and cell class	PPP1R3D MBOAT1 DNAH10	6.40e-04	184	41	3	45f873236f7e90fb78c8e291d3b5b92d121acec9
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 TENM4 DNAH10	6.40e-04	184	41	3	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ABCA4 TENM4 DNAH10	6.40e-04	184	41	3	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_C-D_(RORB)-Glut_D_(IT_RORB_THEMIS_LINC00507)_4-Exc_L4-5_RORB_RPL31P31\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TENM4 ARSJ DNAH6	6.40e-04	184	41	3	9cc5c588f7c6631b3fb8a522214a09ca32947e72
ToppCell	PBMC-Control-Myeloid-Neutrophil-immature_Neutrophil\|Control / Location, Disease Group, Cell group, Cell class (2021.03.09)	PPP1R3D MBOAT1 DNAH10	6.40e-04	184	41	3	84c20730cd92b9aaa50077d7b625e37e7f9e91d2
ToppCell	Control-immature_Neutrophil-\|Control / Disease condition and Cell class	PPP1R3D MBOAT1 DNAH10	6.40e-04	184	41	3	c4e8ba82a6aa76c46f05a71d5f1c7926555318cf
Disease	generalized epilepsy with febrile seizures plus 2 (implicated_via_orthology)	SCN11A SCN4A	7.61e-05	10	39	2	DOID:0111294 (implicated_via_orthology)
Disease	Dravet syndrome (implicated_via_orthology)	SCN11A SCN4A	7.61e-05	10	39	2	DOID:0080422 (implicated_via_orthology)
Disease	Congenital ichthyosis of skin	LIPN ALOX12B	9.29e-05	11	39	2	cv:C0020758
Disease	Congenital Nonbullous Ichthyosiform Erythroderma	LIPN ALOX12B	9.29e-05	11	39	2	C0079154
Disease	generalized epilepsy with febrile seizures plus (implicated_via_orthology)	SCN11A SCN4A	1.11e-04	12	39	2	DOID:0060170 (implicated_via_orthology)
Disease	heart rate	CELSR1 ARSJ L3MBTL3 SIPA1L1	2.20e-04	225	39	4	EFO_0004326

Protein segments in the cluster

Peptide	Gene	Start	Entry
KFSEWGNNAFFYYFE	BCHE	436	P06276
EEFAYCWENFVYNEG	APOBEC3B	151	Q9UH17
SFNWYEDNNYKAFLG	ABCA4	336	P78363
QFLWDFYQGSIFEDA	CELSR1	891	Q9NYQ6
ALFFAYYWDDNFDPA	HSD11B1L	11	Q7Z5J1
YYWDDNFDPASLQGA	HSD11B1L	16	Q7Z5J1
FNGYSAQTAYEDWFI	ATP8B1	971	O43520
LHFDGYSDCYDFWVN	L3MBTL3	296	Q96JM7
ALFADNAYWLENYAN	LIPN	86	Q5VXI9
YYDNQDFPATNWDDK	GRINA	141	Q7Z429
EYWNDVFSDFLNEYE	TRMU	76	O75648
FDYDWYNVSDQADLV	GPR137	251	Q96N19
DLYENDNAAWDYDNG	ARSJ	221	Q5FYB0
DERYFFQGNQYWRYD	MMP21	406	Q8N119
YQFFDESKNWYESQA	KLRK1	111	P26718
DLSDYFNYGFNEDTW	FIP1L1	171	Q6UN15
FNYGFNEDTWKAYCE	FIP1L1	176	Q6UN15
FHFYWLDAYEDQYNQ	POLA1	341	P09884
EFAYCWENFVYSEGQ	APOBEC3F	151	Q8IUX4
YQDFGGFYDRNKLFW	DNAH6	2186	Q9C0G6
QAIQSWFDEYNDFDF	CRISP3	111	P54108
ANWDLFYYRFGQDHA	DNAJC13	756	O75165
DDWENFAYSLGYEPN	LYST	2271	Q99698
EHWAEDTFFGYQYLN	ALOX12B	256	O75342
YYFAWTLADAVNNAA	MBOAT1	296	Q6ZNC8
AWYNETQFYDFDSLS	GLIPR1L1	116	Q6UWM5
GWNVYYDFNESDFQV	DNAH10	4041	Q8IVF4
DADTYGNFNNLRFWY	CFAP47	2526	Q6ZTR5
YQFYWGVEEQEAFEC	RTL1	841	A6NKG5
FDWDAYISDEGNFYF	SCN4A	336	P35499
FYQKEHWNYFGADEN	SIPA1L1	496	O43166
ADWNNCYYTFDGKYE	IARS2	206	Q9NSE4
GNYSGYDDAWDQDRF	POLR1C	31	O15160
DWLYAGDYFERNFSD	OSBPL2	461	Q9H1P3
EAGNYWFDIFNDYAA	SLC6A20	451	Q9NP91
RWGVFDEYNEDQPFY	CLCA4	161	Q14CN2
YADYLFNAIAGNWER	TRABD2B	146	A6NFA1
VAGAEYWDNNDHRDY	PPP1R3D	261	O95685
SNENGWTTFYEYDSF	TENM4	1686	Q6N022
WQAAGQAEYFYEFLS	WIF1	91	Q9Y5W5
DYNYTNFDNFGWSFL	SCN11A	336	Q9UI33
FEQLEYWANNFDDFA	TPCN2	626	Q8NHX9
DTLYFFGDNNFTEWA	JMJD8	131	Q96S16