Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	vesicle cargo loading	SEC24A CTAGE6 MIA2 SURF4 CTAGE15	3.08e-06	36	131	5	GO:0035459
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I	RAET1G ERAP2 ULBP2 RAET1L	1.25e-05	23	131	4	GO:0019885
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen	RAET1G ERAP2 ULBP2 RAET1L	1.77e-05	25	131	4	GO:0002483
GeneOntologyBiologicalProcess	susceptibility to natural killer cell mediated cytotoxicity	RAET1G ULBP2 RAET1L	2.05e-05	9	131	3	GO:0042271
GeneOntologyBiologicalProcess	positive regulation of response to tumor cell	RAET1G CD40LG ULBP2 RAET1L	2.83e-05	28	131	4	GO:0002836
GeneOntologyBiologicalProcess	positive regulation of immune response to tumor cell	RAET1G CD40LG ULBP2 RAET1L	2.83e-05	28	131	4	GO:0002839
GeneOntologyBiologicalProcess	embryo development	ZBTB16 USP22 CAMSAP3 GATA2 GATA3 SALL4 LRP1B DSCAML1 MEIS2 TBX19 LRIG3 SETDB1 SLC9A1 HEG1 SF3B1 NF1 MTHFR CHRD LRP6 TNFAIP3 MAP3K7 KDF1 CNOT1	3.46e-05	1437	131	23	GO:0009790
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous antigen	RAET1G ERAP2 ULBP2 RAET1L	4.87e-05	32	131	4	GO:0019883
GeneOntologyBiologicalProcess	heterochromatin organization	SETDB1 UBR5 MTHFR	6.84e-05	13	131	3	GO:0070828
GeneOntologyBiologicalProcess	regulation of endothelial cell apoptotic process	GATA2 GATA3 CD40LG PRKCI TNFAIP3	1.09e-04	74	131	5	GO:2000351
GeneOntologyBiologicalProcess	positive regulation of T cell mediated immunity	GATA3 RAET1G ULBP2 RAET1L MAP3K7	1.09e-04	74	131	5	GO:0002711
GeneOntologyBiologicalProcess	gamma-aminobutyric acid secretion, neurotransmission	NF1 PAK1	1.20e-04	3	131	2	GO:0061534
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen	HLA-DQB1 RAET1G ERAP2 ULBP2 RAET1L	1.23e-04	76	131	5	GO:0048002
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class I	RAET1G ERAP2 ULBP2 RAET1L	1.31e-04	41	131	4	GO:0002474
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent	RAET1G ULBP2 RAET1L	1.32e-04	16	131	3	GO:0002486
GeneOntologyBiologicalProcess	endothelial cell apoptotic process	GATA2 GATA3 CD40LG PRKCI TNFAIP3	1.48e-04	79	131	5	GO:0072577
GeneOntologyBiologicalProcess	CD40 signaling pathway	FANCD2 CD40LG TNFAIP3	1.60e-04	17	131	3	GO:0023035
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway	RAET1G ULBP2 RAET1L	1.60e-04	17	131	3	GO:0002484
GeneOntologyBiologicalProcess	antigen processing and presentation of endogenous peptide antigen via MHC class Ib	RAET1G ULBP2 RAET1L	1.60e-04	17	131	3	GO:0002476
GeneOntologyBiologicalProcess	antigen processing and presentation of peptide antigen via MHC class Ib	RAET1G ULBP2 RAET1L	1.91e-04	18	131	3	GO:0002428
GeneOntologyBiologicalProcess	antigen processing and presentation	HLA-DQB1 RAET1G ERAP2 ULBP2 RAET1L RAB3B	2.64e-04	139	131	6	GO:0019882
GeneOntologyBiologicalProcess	DNA replication checkpoint signaling	TICRR CAMSAP3 CDC45	2.64e-04	20	131	3	GO:0000076
GeneOntologyBiologicalProcess	regulation of immune response to tumor cell	RAET1G CD40LG ULBP2 RAET1L	2.64e-04	49	131	4	GO:0002837
GeneOntologyBiologicalProcess	embryo development ending in birth or egg hatching	USP22 CAMSAP3 GATA2 GATA3 SALL4 LRP1B DSCAML1 SETDB1 HEG1 SF3B1 NF1 MTHFR CHRD LRP6 MAP3K7 CNOT1	2.72e-04	929	131	16	GO:0009792
GeneOntologyBiologicalProcess	regulation of response to tumor cell	RAET1G CD40LG ULBP2 RAET1L	2.85e-04	50	131	4	GO:0002834
GeneOntologyBiologicalProcess	regulation of transcription by RNA polymerase I	FLNA SF3B1 BAZ2A MTOR	2.85e-04	50	131	4	GO:0006356
GeneOntologyBiologicalProcess	long-term synaptic potentiation	NF1 SHANK2 PAK1 CHRD PRKCG SLC24A1	3.19e-04	144	131	6	GO:0060291
GeneOntologyBiologicalProcess	response to organic cyclic compound	NCOA2 FLNA RAET1G SSTR2 ARPC1B RYR3 SLC9A1 UBR5 MTOR MTHFR PAK1 LRP6 ULBP2 PRKCG RAET1L CNOT1 TBL1X	3.48e-04	1048	131	17	GO:0014070
GeneOntologyBiologicalProcess	cellular response to exogenous dsRNA	RAET1G ULBP2 RAET1L	3.53e-04	22	131	3	GO:0071360
GeneOntologyBiologicalProcess	formation of radial glial scaffolds	FLNA LRP6	3.95e-04	5	131	2	GO:0021943
GeneOntologyBiologicalProcess	regulation of epithelial cell apoptotic process	GATA2 GATA3 MTOR CD40LG PRKCI TNFAIP3	4.25e-04	152	131	6	GO:1904035
GeneOntologyBiologicalProcess	immune response to tumor cell	RAET1G CD40LG ULBP2 RAET1L	4.42e-04	56	131	4	GO:0002418
GeneOntologyBiologicalProcess	cellular response to organic cyclic compound	NCOA2 FLNA RAET1G SSTR2 RYR3 SLC9A1 UBR5 PAK1 LRP6 ULBP2 RAET1L CNOT1	4.83e-04	605	131	12	GO:0071407
GeneOntologyCellularComponent	endoplasmic reticulum exit site	SEC24A CTAGE6 MIA2 SURF4 CTAGE15	6.32e-06	42	131	5	GO:0070971
GeneOntologyCellularComponent	nuclear body	NCOA2 CASP8AP2 ZBTB16 TCF12 DDX42 ZNF217 FANCD2 SF3B1 TELO2 BAZ2A MTOR CSNK2A1 SETBP1 AFDN SRRM2 ADGRD1	1.70e-04	903	131	16	GO:0016604
GeneOntologyCellularComponent	protein kinase CK2 complex	CSNK2A1 CSNK2A3	2.32e-04	4	131	2	GO:0005956
GeneOntologyCellularComponent	nuclear protein-containing complex	NCOA2 FLNA ERCC5 TCF12 USP22 NUP85 WDR33 UBE2C DDX42 CAMSAP3 ZNF217 CDC45 SF3B1 BAZ2A CSNK2A1 SYNE2 AEBP2 SRRM2 MGA TBL1X	3.62e-04	1377	131	20	GO:0140513
GeneOntologyCellularComponent	anchoring junction	FLNA ATP6V0C SORBS2 ASH1L CAMSAP3 ARPC1B SLC9A1 HEG1 SYNE2 PAK1 TLN2 AFDN PRKCG PRKCI KDF1 HCK	4.05e-04	976	131	16	GO:0070161
HumanPheno	Aplasia/Hypoplasia of the phalanges of the thumb	FLNA SALL4 FANCD2 SETBP1 MAP3K7 CNOT1	5.14e-06	46	51	6	HP:0009658
HumanPheno	Shoulder muscle hypoplasia	FLNA SALL4 MAP3K7	9.33e-06	5	51	3	HP:0008952
HumanPheno	Aplasia/Hypoplasia involving the shoulder musculature	FLNA SALL4 MAP3K7	9.33e-06	5	51	3	HP:0001464
HumanPheno	Aplasia/Hypoplasia involving the musculature of the extremities	FLNA SALL4 MAP3K7	1.85e-05	6	51	3	HP:0009128
HumanPheno	Aplasia/Hypoplasia involving the musculature of the upper limbs	FLNA SALL4 MAP3K7	1.85e-05	6	51	3	HP:0001467
HumanPheno	Aplasia/Hypoplasia of the distal phalanx of the thumb	FLNA SALL4 MAP3K7	7.61e-05	9	51	3	HP:0009641
HumanPheno	Short distal phalanx of the thumb	FLNA SALL4 MAP3K7	7.61e-05	9	51	3	HP:0009650
HumanPheno	Short diaphyses	FLNA MAP3K7	9.83e-05	2	51	2	HP:0000941
HumanPheno	Abnormality of thumb phalanx	FLNA ATP6V1B2 SALL4 ADA2 MEIS2 FANCD2 SETBP1 MAP3K7 CNOT1	1.62e-04	205	51	9	HP:0009602
HumanPheno	Supernumerary tooth	FLNA ATP6V1B2 TCF12 CHD6 AMMECR1 KDF1	1.78e-04	85	51	6	HP:0011069
HumanPheno	Abnormal palate morphology	FLNA ATP6V1B2 ERCC5 ASH1L GATA3 SALL4 ADA2 WDR26 MEIS2 RYR3 CDC45 FANCD2 NF1 TELO2 MTHFR CSNK2A1 SETBP1 LRP6 CHD6 PLCB4 AMMECR1 MAP3K7 KDF1 CNOT1	1.95e-04	1202	51	24	HP:0000174
HumanPheno	Triangular shaped phalanges of the hand	FLNA ATP6V1B2 SALL4 ADA2 MEIS2 FANCD2 SETBP1 MAP3K7 CNOT1	2.25e-04	214	51	9	HP:0009774
HumanPheno	Short thumb	FLNA ATP6V1B2 SALL4 ADA2 FANCD2 SETBP1 MAP3K7	2.36e-04	127	51	7	HP:0009778
HumanPheno	Orofacial cleft	FLNA ATP6V1B2 ERCC5 GATA3 SALL4 ADA2 WDR26 MEIS2 CDC45 FANCD2 TELO2 MTHFR LRP6 PLCB4 AMMECR1 MAP3K7 KDF1	2.53e-04	694	51	17	HP:0000202
HumanPheno	Craniofacial cleft	FLNA ATP6V1B2 ERCC5 GATA3 SALL4 ADA2 WDR26 MEIS2 CDC45 FANCD2 TELO2 MTHFR LRP6 PLCB4 AMMECR1 MAP3K7 KDF1	2.53e-04	694	51	17	HP:5201015
HumanPheno	Deviation of the hand or of fingers of the hand	FLNA ATP6V1B2 NUP85 SALL4 WDR26 RYR3 CDC45 FANCD2 TELO2 CSNK2A1 SETBP1 CHD6 AMMECR1 MAP3K7 CNOT1	2.72e-04	564	51	15	HP:0009484
HumanPheno	Micrognathia	FLNA ATP6V1B2 ERCC5 NUP85 SALL4 ANKLE2 ADA2 WDR26 RYR3 CDC45 FANCD2 NF1 TELO2 CSNK2A1 SETBP1 CHD6 PLCB4 AMMECR1 MAP3K7	2.84e-04	843	51	19	HP:0000347
HumanPheno	Hypotrophy of the small hand muscles	FLNA MAP3K7	2.93e-04	3	51	2	HP:0006006
HumanPheno	Inappropriately normal thyroid-stimulating hormone level	IGSF1 TBL1X	2.93e-04	3	51	2	HP:0033075
HumanPheno	Progressive bowing of long bones	FLNA MAP3K7	2.93e-04	3	51	2	HP:0006383
HumanPheno	Aplasia/Hypoplasia of the mandible	FLNA ATP6V1B2 ERCC5 NUP85 SALL4 ANKLE2 ADA2 WDR26 RYR3 CDC45 FANCD2 NF1 TELO2 CSNK2A1 SETBP1 CHD6 PLCB4 AMMECR1 MAP3K7	2.93e-04	845	51	19	HP:0009118
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	NCOA2 SORBS2 CAMSAP3 WDR26 SF3B1 NF1 SEPTIN3 SHANK2 UBR5 MTOR CSNK2A1 ARHGAP44 SYNE2 PAK1 ELAVL2 ANKRD28 TLN2 AFDN PRKCG PRKCI CEP131 MGA RAB3B CNOT1 TBL1X	4.27e-14	963	134	25	28671696
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	CASP8AP2 FLNA CAMSAP3 USP24 ZNF217 ECPAS WDR26 SETDB1 ZNF608 UBR5 ANKRD28 CEP131 CHD6 MGA CNOT1 TBL1X	7.96e-12	418	134	16	34709266
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	PRUNE2 CASP8AP2 DSCAML1 ZNF608 UBR5 SETBP1 SYNE2 ANKRD28 TLN2 RPRD2 CHD6	1.33e-09	225	134	11	12168954
Pubmed	Genome-wide CRISPR screen identifies HNRNPL as a prostate cancer dependency regulating RNA splicing.	NCOA2 PRUNE2 ZBTB16 ASH1L CAMSAP3 ECPAS STEAP2 SNX29 PLEKHH1 SHANK2 KCNQ5 UBE2H ZNF608 SETBP1 ARHGAP44 PRKCI RPRD2 CHD6 PLCB4 AADAT CATSPERG CNOT1 ADGRD1 TBL1X	2.62e-09	1489	134	24	28611215
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	SORBS2 ZBTB16 ARHGEF28 USP22 SEC24A CAMSAP3 PTPN21 WDR26 NF1 KCNQ5 MTOR SYNE2 AFDN PRKCG PRKCI CEP131 TNFAIP3 SRRM2	6.39e-09	861	134	18	36931259
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 ECPAS BAZ2A ANKRD28 TLN2 IGSF1 SRRM2 DNAH9	7.42e-09	104	134	8	9205841
Pubmed	Human transcription factor protein interaction networks.	NCOA2 TCF12 USP22 WDR33 SEC24A GATA2 GATA3 ZNF217 SETDB1 ZNF608 CSNK2A1 SYNE2 LRP6 ELAVL2 ANKRD28 RPRD2 CEP131 CHD6 SRRM2 MGA CNOT1 TBL1X	2.97e-08	1429	134	22	35140242
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	FLNA DDX42 USP24 ECPAS SF3B1 NF1 UBR5 BAZ2A MTOR CSNK2A1 SYNE2 ANKRD28 AFDN SRRM2 CNOT1	3.78e-08	653	134	15	22586326
Pubmed	Human anaplastic thyroid carcinoma cells are sensitive to NK cell-mediated lysis via ULBP2/5/6 and chemoattract NK cells.	RAET1G ULBP2 RAET1L	5.59e-08	3	134	3	25212604
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	TCF12 USP22 ASH1L WDR26 FANCD2 LRIG3 SETDB1 ZNF608 UBR5 TELO2 BAZ2A MTHFR CSNK2A1 CBY2 RTL9 ANKRD28 TIGD5 SRRM2 MGA	6.15e-08	1116	134	19	31753913
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	FLNA SORBS2 CAMSAP3 USP24 ANKLE2 WDR26 LRP1B SF3B1 NF1 SEPTIN3 SHANK2 KCNQ5 ANKRD28 TLN2 AFDN PRKCG CEP131 MAP3K7 CNOT1	8.45e-08	1139	134	19	36417873
Pubmed	Direct interaction of the mouse cytomegalovirus m152/gp40 immunoevasin with RAE-1 isoforms.	RAET1G ULBP2 RAET1L	2.23e-07	4	134	3	20166740
Pubmed	Cutting edge: tumor rejection mediated by NKG2D receptor-ligand interaction is dependent upon perforin.	RAET1G ULBP2 RAET1L	2.23e-07	4	134	3	12421908
Pubmed	NKG2D-mediated natural killer cell protection against cytomegalovirus is impaired by viral gp40 modulation of retinoic acid early inducible 1 gene molecules.	RAET1G ULBP2 RAET1L	2.23e-07	4	134	3	12756263
Pubmed	Murine NKG2D ligands: "double, double toil and trouble".	RAET1G ULBP2 RAET1L	2.23e-07	4	134	3	19081632
Pubmed	Isolation and characterization of retinoic acid-inducible cDNA clones in F9 cells: a novel cDNA family encodes cell surface proteins sharing partial homology with MHC class I molecules.	RAET1G ULBP2 RAET1L	2.23e-07	4	134	3	8882725
Pubmed	SNX27-driven membrane localisation of OTULIN antagonises linear ubiquitination and NF-κB signalling activation.	SORBS2 ERCC5 NUP85 SEC24A CAMSAP3 WDR26 PAK1 ANKRD28 AFDN MAP3K7 MGA	2.70e-07	378	134	11	34315543
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	FLNA SORBS2 ERCC5 CAMSAP3 USP24 ZNF217 ECPAS FANCD2 SF3B1 NF1 BAZ2A CSNK2A1 TLN2 AFDN SRRM2	3.35e-07	774	134	15	15302935
Pubmed	Functional specialization of beta-arrestin interactions revealed by proteomic analysis.	FLNA USP24 WDR26 LRP1B SF3B1 UBR5 CSNK2A1 AFDN SRRM2 MAP3K7	4.62e-07	317	134	10	17620599
Pubmed	Chr21 protein-protein interactions: enrichment in proteins involved in intellectual disability, autism, and late-onset Alzheimer's disease.	NCOA2 ZNF821 ATP6V1B2 SORBS2 ASH1L WDR26 LRP1B DSCAML1 TRAPPC1 RYR3 PLEKHH1 SETDB1 SF3B1 SEPTIN3 MIA2 PAK1 TLN2 AFDN CHD6	5.31e-07	1285	134	19	35914814
Pubmed	MULT1E/mIL-12: a novel bifunctional protein for natural killer cell activation.	RAET1G ULBP2 RAET1L	5.56e-07	5	134	3	24572784
Pubmed	Genomic structures and characterization of Rae1 family members encoding GPI-anchored cell surface proteins and expressed predominantly in embryonic mouse brain.	RAET1G ULBP2 RAET1L	5.56e-07	5	134	3	8982867
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	NCOA2 WDR33 DDX42 ZNF217 ZNF608 CSNK2A1 RPRD2 MGA TBL1X	1.06e-06	268	134	9	33640491
Pubmed	Crystal structures of RAE-1beta and its complex with the activating immunoreceptor NKG2D.	RAET1G ULBP2 RAET1L	1.11e-06	6	134	3	11825567
Pubmed	Retinoic acid early inducible genes define a ligand family for the activating NKG2D receptor in mice.	RAET1G ULBP2 RAET1L	1.11e-06	6	134	3	10894171
Pubmed	Ligands for murine NKG2D display heterogeneous binding behavior.	RAET1G ULBP2 RAET1L	1.11e-06	6	134	3	11857333
Pubmed	Single nucleotide polymorphism analysis of the NKG2D ligand cluster on the long arm of chromosome 6: Extensive polymorphisms and evidence of diversity between human populations.	RAET1G ULBP2 RAET1L	1.11e-06	6	134	3	20219610
Pubmed	The NKG2D ligands RAE-1δ and RAE-1ε differ with respect to their receptor affinity, expression profiles and transcriptional regulation.	RAET1G ULBP2 RAET1L	1.11e-06	6	134	3	20976056
Pubmed	Polymorphisms of NKG2D ligands: diverse RAET1/ULBP genes in northeastern Thais.	RAET1G ULBP2 RAET1L	1.11e-06	6	134	3	19688209
Pubmed	SARS-CoV-2 Nsp6 damages Drosophila heart and mouse cardiomyocytes through MGA/MAX complex-mediated increased glycolysis.	FLNA NUP85 CAMSAP3 ECPAS FANCD2 SF3B1 NF1 UBR5 TELO2 MTOR MAP3K7 MGA CNOT1	1.70e-06	657	134	13	36180527
Pubmed	The herpesviral Fc receptor fcr-1 down-regulates the NKG2D ligands MULT-1 and H60.	RAET1G ULBP2 RAET1L	1.94e-06	7	134	3	16831899
Pubmed	Stress-regulated targeting of the NKG2D ligand Mult1 by a membrane-associated RING-CH family E3 ligase.	RAET1G ULBP2 RAET1L	1.94e-06	7	134	3	20870941
Pubmed	Critical role of the NKG2D receptor for NK cell-mediated control and immune escape of B-cell lymphoma.	RAET1G ULBP2 RAET1L	1.94e-06	7	134	3	26151313
Pubmed	NKG2D and Its Ligand MULT1 Contribute to Disease Progression in a Mouse Model of Multiple Sclerosis.	RAET1G ULBP2 RAET1L	1.94e-06	7	134	3	30787931
Pubmed	Cutting edge: murine UL16-binding protein-like transcript 1: a newly described transcript encoding a high-affinity ligand for murine NKG2D.	RAET1G ULBP2 RAET1L	1.94e-06	7	134	3	12370332
Pubmed	NKG2D ligand overexpression in lupus nephritis correlates with increased NK cell activity and differentiation in kidneys but not in the periphery.	RAET1G ULBP2 RAET1L	1.94e-06	7	134	3	25583577
Pubmed	In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.	FLNA ERCC5 NUP85 WDR33 DDX42 ASH1L CAMSAP3 CTAGE6 PTPN21 ANKLE2 SF3B1 MIA2 SHANK2 ZNF608 TCHHL1 SYNE2 CTAGE15 CHD6 RAB3B	2.91e-06	1442	134	19	35575683
Pubmed	Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.	ATP6V1B2 SEC24A CAMSAP3 PTPN21 ANKLE2 FANCD2 TELO2 CSNK2A1 SYNE2 LRP6 ANKRD28 PRKCI CEP131 SRRM2 MAP3K7 CNOT1	3.05e-06	1049	134	16	27880917
Pubmed	A novel ligand for the NKG2D receptor activates NK cells and macrophages and induces tumor immunity.	RAET1G ULBP2 RAET1L	3.09e-06	8	134	3	12645935
Pubmed	A human MAP kinase interactome.	CASP8AP2 FLNA SETDB1 SLC9A1 SF3B1 PAK1 CHD6 TNFAIP3 MAP3K7 MGA HCK	3.11e-06	486	134	11	20936779
Pubmed	Functional proteomics mapping of a human signaling pathway.	FLNA ZBTB16 ASH1L ANKLE2 SETDB1 SF3B1 UBR5 ANKRD28 AFDN CHD6 TNFAIP3 MGA	3.33e-06	591	134	12	15231748
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	FLNA CAMSAP3 USP24 ANKLE2 SF3B1 PAK1 TLN2 AFDN RPRD2 CEP131 SRRM2	4.32e-06	503	134	11	16964243
Pubmed	Characterization of SARS-CoV-2 proteins reveals Orf6 pathogenicity, subcellular localization, host interactions and attenuation by Selinexor.	FLNA CAMSAP3 ECPAS SF3B1 NF1 UBR5 TELO2 MAP3K7 MGA CNOT1	4.43e-06	408	134	10	33766124
Pubmed	S. pombe Uba1-Ubc15 Structure Reveals a Novel Regulatory Mechanism of Ubiquitin E2 Activity.	FANCD2 UBE2H PRKCG	4.62e-06	9	134	3	28162934
Pubmed	Cutting edge: Toll-like receptor signaling in macrophages induces ligands for the NKG2D receptor.	RAET1G ULBP2 RAET1L	4.62e-06	9	134	3	14764662
Pubmed	Gut microbiota regulates NKG2D ligand expression on intestinal epithelial cells.	RAET1G ULBP2 RAET1L	4.62e-06	9	134	3	23136011
Pubmed	A Human Tyrosine Phosphatase Interactome Mapped by Proteomic Profiling.	MPO FLNA NUP85 PTPN21 ECPAS WDR26 CDC45 FANCD2 UBR5 TELO2 MTOR CSNK2A1 ANKRD28 AFDN SRRM2	5.66e-06	974	134	15	28675297
Pubmed	A cluster of ten novel MHC class I related genes on human chromosome 6q24.2-q25.3.	RAET1G ULBP2 RAET1L	6.58e-06	10	134	3	11827464
Pubmed	Tissue-Specific Regulation of the Wnt/β-Catenin Pathway by PAGE4 Inhibition of Tankyrase.	FLNA CAMSAP3 WDR26 SF3B1 ANKRD28 SRRM2 MAP3K7 MGA	7.24e-06	256	134	8	32698014
Pubmed	Targeting TRIM37-driven centrosome dysfunction in 17q23-amplified breast cancer.	TCF12 ZNF217 ANKLE2 UBR5 RPRD2 CEP131 MGA	7.71e-06	184	134	7	32908313
Pubmed	Cell Surface Downregulation of NK Cell Ligands by Patient-Derived HIV-1 Vpu and Nef Alleles.	RAET1G ULBP2 RAET1L	9.02e-06	11	134	3	26656785
Pubmed	Identification of proximal SUMO-dependent interactors using SUMO-ID.	ZNF280A MPO NCOA2 FLNA TCF12 DDX42 SF3B1 ZNF608 PAK1 MGA	9.27e-06	444	134	10	34795231
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	FLNA ATP6V1B2 NUP85 DDX42 SF3B1 NF1 UBR5 CSNK2A1 SURF4 SYNE2 AFDN CEP131 SRRM2 MGA CNOT1	1.02e-05	1024	134	15	24711643
Pubmed	An organelle-specific protein landscape identifies novel diseases and molecular mechanisms.	CAMSAP3 ANKLE2 WDR26 TRAPPC1 SETDB1 NF1 UBE2H MTOR CSNK2A1 SURF4 ARHGAP44 RTL9 ANKRD28 AFDN PRKCI CEP131 CNOT1	1.37e-05	1321	134	17	27173435
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	FLNA SALL4 ECPAS MTOR SURF4 MROH7 CNOT1	1.41e-05	202	134	7	33005030
Pubmed	Synaptic GAP and GEF Complexes Cluster Proteins Essential for GTP Signaling.	SORBS2 CAMSAP3 NF1 SHANK2 UBR5 MTOR TLN2 PRKCG	1.42e-05	281	134	8	28706196
Pubmed	Characterization of the glycinergic input to bipolar cells of the mouse retina.	GLRA3 GLRA1	1.47e-05	2	134	2	16420443
Pubmed	Phosphorylation of α3 glycine receptors induces a conformational change in the glycine-binding site.	GLRA3 GLRA1	1.47e-05	2	134	2	23834509
Pubmed	Tumor suppressor A20 protects against cardiac hypertrophy and fibrosis by blocking transforming growth factor-beta-activated kinase 1-dependent signaling.	TNFAIP3 MAP3K7	1.47e-05	2	134	2	20585109
Pubmed	GATA motifs regulate early hematopoietic lineage-specific expression of the Gata2 gene.	GATA2 GATA3	1.47e-05	2	134	2	16055713
Pubmed	Tyrosyl phosphorylated PAK1 regulates breast cancer cell motility in response to prolactin through filamin A.	FLNA PAK1	1.47e-05	2	134	2	23340249
Pubmed	Vibrio vulnificus RtxA1 cytotoxin targets filamin A to regulate PAK1- and MAPK-dependent cytoskeleton reorganization and cell death.	FLNA PAK1	1.47e-05	2	134	2	31237474
Pubmed	Follicular lymphoma-associated mutations in vacuolar ATPase ATP6V1B2 activate autophagic flux and mTOR.	ATP6V1B2 MTOR	1.47e-05	2	134	2	30720463
Pubmed	GATA2-dependent and region-specific regulation of Gata2 transcription in the mouse midbrain.	GATA2 GATA3	1.47e-05	2	134	2	19371385
Pubmed	Social learning and amygdala disruptions in Nf1 mice are rescued by blocking p21-activated kinase.	NF1 PAK1	1.47e-05	2	134	2	25242307
Pubmed	MTHFR Glu429Ala and ERCC5 His46His polymorphisms are associated with prognosis in colorectal cancer patients: analysis of two independent cohorts from Newfoundland.	ERCC5 MTHFR	1.47e-05	2	134	2	23626689
Pubmed	Protein kinase C iota promotes glycolysis via PI3K/AKT/mTOR signalling in high grade serous ovarian cancer.	MTOR PRKCI	1.47e-05	2	134	2	39276277
Pubmed	DNA repair gene and MTHFR gene polymorphisms as prognostic markers in locally advanced adenocarcinoma of the esophagus or stomach treated with cisplatin and 5-fluorouracil-based neoadjuvant chemotherapy.	ERCC5 MTHFR	1.47e-05	2	134	2	21347786
Pubmed	The essential role of GATA transcription factors in adult murine prostate.	GATA2 GATA3	1.47e-05	2	134	2	27374105
Pubmed	GATA3 is downregulated during hair cell differentiation in the mouse cochlea.	GATA2 GATA3	1.47e-05	2	134	2	10447238
Pubmed	Context-dependent function of regulatory elements and a switch in chromatin occupancy between GATA3 and GATA2 regulate Gata2 transcription during trophoblast differentiation.	GATA2 GATA3	1.47e-05	2	134	2	19106099
Pubmed	Filamin A (FLNA) plays an essential role in somatostatin receptor 2 (SST2) signaling and stabilization after agonist stimulation in human and rat somatotroph tumor cells.	FLNA SSTR2	1.47e-05	2	134	2	24828612
Pubmed	Probing glycine receptor stoichiometry in superficial dorsal horn neurones using the spasmodic mouse.	GLRA3 GLRA1	1.47e-05	2	134	2	21486794
Pubmed	Deubiquitinase function of A20 maintains and repairs endothelial barrier after lung vascular injury.	TNFAIP3 MAP3K7	1.47e-05	2	134	2	29796309
Pubmed	Hyperactivation of mTOR critically regulates abnormal osteoclastogenesis in neurofibromatosis Type 1.	NF1 MTOR	1.47e-05	2	134	2	21748792
Pubmed	Assignment of casein kinase 2 alpha sequences to two different human chromosomes.	CSNK2A1 CSNK2A3	1.47e-05	2	134	2	1577469
Pubmed	Functional antagonism between Sall4 and Plzf defines germline progenitors.	ZBTB16 SALL4	1.47e-05	2	134	2	22385656
Pubmed	Cancer-associated mutations in SF3B1 disrupt the interaction between SF3B1 and DDX42.	DDX42 SF3B1	1.47e-05	2	134	2	35652295
Pubmed	SF3B1 mutant-induced missplicing of MAP3K7 causes anemia in myelodysplastic syndromes.	SF3B1 MAP3K7	1.47e-05	2	134	2	34930825
Pubmed	Filamin-A is required to mediate SST2 effects in pancreatic neuroendocrine tumours.	FLNA SSTR2	1.47e-05	2	134	2	26733502
Pubmed	Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.	CSNK2A1 CSNK2A3	1.47e-05	2	134	2	14646071
Pubmed	Oncogenic protein SALL4 and ZNF217 as prognostic indicators in solid cancers: a meta‑analysis of individual studies.	SALL4 ZNF217	1.47e-05	2	134	2	27007163
Pubmed	Characterization of the aberrant splicing of MAP3K7 induced by cancer-associated SF3B1 mutation.	SF3B1 MAP3K7	1.47e-05	2	134	2	33751071
Pubmed	Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.	CSNK2A1 CSNK2A3	1.47e-05	2	134	2	12860116
Pubmed	Genetic variability of the mTOR pathway and prostate cancer risk in the European Prospective Investigation on Cancer (EPIC).	MTOR PRKCI	1.47e-05	2	134	2	21373201
Pubmed	The GATA transcriptional program dictates cell fate equilibrium to establish the maternal-fetal exchange interface and fetal development.	GATA2 GATA3	1.47e-05	2	134	2	38346193
Pubmed	Multifunctional basic motif in the glycine receptor intracellular domain induces subunit-specific sorting.	GLRA3 GLRA1	1.47e-05	2	134	2	19959465
Pubmed	Tumor necrosis factor alpha receptor- and Fas-associated FLASH inhibit transcriptional activity of the glucocorticoid receptor by binding to and interfering with its interaction with p160 type nuclear receptor coactivators.	NCOA2 CASP8AP2	1.47e-05	2	134	2	12477726
Pubmed	Filamin is essential in actin cytoskeletal assembly mediated by p21-activated kinase 1.	FLNA PAK1	1.47e-05	2	134	2	12198493
Pubmed	The T-box factor Tpit recruits SRC/p160 co-activators and mediates hormone action.	NCOA2 TBX19	1.47e-05	2	134	2	12970370
Pubmed	UBE2C Drives Human Cervical Cancer Progression and Is Positively Modulated by mTOR.	UBE2C MTOR	1.47e-05	2	134	2	33396624
Pubmed	Oral administration of K-11706 inhibits GATA binding activity, enhances hypoxia-inducible factor 1 binding activity, and restores indicators in an in vivo mouse model of anemia of chronic disease.	GATA2 GATA3	1.47e-05	2	134	2	15328158
Pubmed	GATA factor activity is required for the trophoblast-specific transcriptional regulation of the mouse placental lactogen I gene.	GATA2 GATA3	1.47e-05	2	134	2	7720565
Pubmed	Molecular cloning of the human casein kinase II alpha subunit.	CSNK2A1 CSNK2A3	1.47e-05	2	134	2	2752008
Pubmed	Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.	CSNK2A1 CSNK2A3	1.47e-05	2	134	2	8420794
Pubmed	Protein kinase CK2 phosphorylates and activates p21-activated kinase 1.	CSNK2A1 PAK1	1.47e-05	2	134	2	23885116
Pubmed	cPKCγ-Modulated Sequential Reactivation of mTOR Inhibited Autophagic Flux in Neurons Exposed to Oxygen Glucose Deprivation/Reperfusion.	MTOR PRKCG	1.47e-05	2	134	2	29734780
Pubmed	Fanconi anemia and mTOR pathways functionally interact during stalled replication fork recovery.	FANCD2 MTOR	1.47e-05	2	134	2	33423298
Pubmed	HIV-1 reverse transcriptase is phosphorylated in vitro and in a cellular system.	CSNK2A1 PRKCG PRKCI	1.55e-05	13	134	3	10641798
Pubmed	Quantitative Proteomics Links the LRRC59 Interactome to mRNA Translation on the ER Membrane.	FLNA ANKLE2 LRP1B SLC9A1 SF3B1 SURF4 SYNE2 AFDN CNOT1	1.60e-05	375	134	9	32788342
Interaction	KDM1A interactions	ZNF280A CASP8AP2 FLNA USP22 CAMSAP3 USP24 GATA2 GATA3 ZNF217 ECPAS WDR26 FANCD2 SETDB1 UBE2H ZNF608 UBR5 CSNK2A1 ANKRD28 CEP131 CHD6 MGA CNOT1 TBL1X	3.83e-08	941	131	23	int:KDM1A
Interaction	RCOR1 interactions	CASP8AP2 FLNA CAMSAP3 USP24 GATA2 GATA3 ZNF217 ECPAS WDR26 UBE2H UBR5 CSNK2A1 CEP131 CHD6 MGA TBL1X	1.39e-07	494	131	16	int:RCOR1
Interaction	HDAC1 interactions	ANKRD13B CASP8AP2 FLNA ZBTB16 CAMSAP3 USP24 GATA3 SALL4 ZNF217 ECPAS WDR26 FANCD2 SETDB1 ZNF608 UBR5 BAZ2A CSNK2A1 SYNE2 ANKRD28 CEP131 MGA CSNK2A3 TBL1X	6.99e-07	1108	131	23	int:HDAC1
Interaction	DCAF7 interactions	FLNA SEC24A CAMSAP3 GATA2 GATA3 ZNF217 FANCD2 UBE2H CSNK2A1 PRKCI SRRM2 KDF1 CSNK2A3	8.47e-07	368	131	13	int:DCAF7
Interaction	YWHAB interactions	TICRR SORBS2 ARHGEF28 SEC24A SH2D3A CAMSAP3 PTPN21 TRAPPC1 FANCD2 SLC9A1 NF1 KCNQ5 UBE2H MTOR CSNK2A1 AFDN PRKCG PRKCI CEP131 TNFAIP3 SRRM2	2.36e-06	1014	131	21	int:YWHAB
Interaction	YWHAH interactions	NCOA2 TICRR SORBS2 ARHGEF28 USP22 SEC24A CAMSAP3 PTPN21 WDR26 TRAPPC1 FANCD2 NF1 KCNQ5 UBE2H MTOR SYNE2 AFDN PRKCI CEP131 TNFAIP3 SRRM2 MAP3K7	2.40e-06	1102	131	22	int:YWHAH
Interaction	NUP43 interactions	CASP8AP2 FLNA ERCC5 NUP85 ASH1L FANCD2 ZNF608 UBR5 BAZ2A SYNE2 ANKRD28 CHD6 SRRM2 MGA DNAH9 CNOT1	3.07e-06	625	131	16	int:NUP43
Interaction	YWHAG interactions	FLNA TICRR SORBS2 ARHGEF28 USP22 SEC24A SH2D3A CAMSAP3 USP24 PTPN21 FANCD2 NF1 KCNQ5 UBE2H MTOR SYNE2 PAK1 AFDN PRKCG PRKCI CEP131 TNFAIP3 SRRM2	5.22e-06	1248	131	23	int:YWHAG
Interaction	TLE3 interactions	NCOA2 FLNA TCF12 SEC24A GATA2 GATA3 ZNF217 UBE2H ZNF608 UBR5 CHD6 SRRM2	6.46e-06	376	131	12	int:TLE3
Interaction	HIF1AN interactions	TCF12 USP24 CDC45 NKAPD1 SYNE2 ANKRD28 TLN2 AFDN RPRD2 MAP3K7 CNOT1	7.28e-06	317	131	11	int:HIF1AN
Interaction	PML interactions	ZNF280A MPO NCOA2 CASP8AP2 FLNA ZBTB16 TCF12 DDX42 GATA2 FANCD2 SETDB1 NF1 ZNF608 UBR5 MTOR CSNK2A1 SYNE2 PAK1 CSNK2A3	9.60e-06	933	131	19	int:PML
Interaction	RANBP10 interactions	PTPN21 WDR26 UBE2H PRKCG TIGD5 IGSF1 KDF1	1.21e-05	118	131	7	int:RANBP10
Interaction	PHF21A interactions	CASP8AP2 FLNA USP24 ZNF217 ECPAS WDR26 UBR5 ANKRD28 CEP131 CHD6 MGA	1.52e-05	343	131	11	int:PHF21A
Interaction	YWHAE interactions	FLNA TICRR SORBS2 ARHGEF28 SEC24A SH2D3A CAMSAP3 PTPN21 FANCD2 SF3B1 NF1 KCNQ5 UBE2H MTOR AFDN PRKCG PRKCI CEP131 TNFAIP3 SRRM2 MAP3K7 MGA	1.90e-05	1256	131	22	int:YWHAE
Interaction	AR interactions	NCOA2 FLNA ZBTB16 USP22 WDR33 UBE2C DDX42 ZNF217 ECPAS SF3B1 ZNF608 UBR5 TELO2 CSNK2A1 RPRD2 CEP131 MGA HCK TBL1X	2.26e-05	992	131	19	int:AR
Interaction	ELP1 interactions	FLNA NUP85 ZNF217 FANCD2 SF3B1 UBE2H MAP3K7 KDF1	2.55e-05	182	131	8	int:ELP1
Interaction	CTAGE1 interactions	CTAGE6 MIA2 CTAGE15	3.12e-05	10	131	3	int:CTAGE1
Interaction	CDCA5 interactions	FLNA CAMSAP3 WDR26 FANCD2 SF3B1 CHD6 MGA	3.66e-05	140	131	7	int:CDCA5
Interaction	YWHAZ interactions	TICRR SORBS2 ARHGEF28 SEC24A SH2D3A CAMSAP3 PTPN21 TRAPPC1 FANCD2 SLC9A1 SF3B1 NF1 KCNQ5 UBE2H MTOR SYNE2 PAK1 ANKRD28 AFDN PRKCI CEP131 TNFAIP3	4.01e-05	1319	131	22	int:YWHAZ
Interaction	VSX1 interactions	SETDB1 ZNF608 CSNK2A1 CHD6 TBL1X	6.99e-05	66	131	5	int:VSX1
Interaction	SNRNP40 interactions	CASP8AP2 FLNA TCF12 ZNF217 SF3B1 UBE2H ZNF608 UBR5 BAZ2A NKAPD1 SURF4 SRRM2 MGA TBL1X	7.02e-05	637	131	14	int:SNRNP40
Interaction	PRPSAP1 interactions	FANCD2 UBE2H PAK1 ANKRD28 PRKCG HCK	7.10e-05	107	131	6	int:PRPSAP1
Interaction	WDR5 interactions	FLNA ATP6V1B2 NUP85 SALL4 PTPN21 ECPAS WDR26 MEIS2 SF3B1 UBE2H ZNF608 UBR5 MTOR CSNK2A1 SURF4 SETBP1 AFDN MAP3K7 MGA	9.18e-05	1101	131	19	int:WDR5
Interaction	RCN2 interactions	ATP6V1B2 ZNF217 ECPAS FANCD2 UBE2H PAK1 ANKRD28 PRKCG PRKCI	9.66e-05	282	131	9	int:RCN2
Interaction	USP9X interactions	UBE2C USP24 GATA3 SALL4 PTPN21 ECPAS UBE2H MTOR AFDN MAP3K7 KDF1	9.96e-05	422	131	11	int:USP9X
Interaction	SIRT7 interactions	FLNA DDX42 USP24 ECPAS SF3B1 NF1 UBR5 BAZ2A MTOR CSNK2A1 SYNE2 ANKRD28 AFDN SRRM2 CNOT1	1.01e-04	744	131	15	int:SIRT7
Interaction	MCM6 interactions	ZNF217 CDC45 FANCD2 SF3B1 UBE2H PRKCI TNFAIP3 SRRM2 KDF1	1.10e-04	287	131	9	int:MCM6
Interaction	YWHAQ interactions	FLNA TICRR SORBS2 ARHGEF28 USP22 SEC24A SH2D3A CAMSAP3 TRAPPC1 FANCD2 NF1 KCNQ5 UBE2H MTOR CSNK2A1 AFDN PRKCI CEP131 TNFAIP3	1.12e-04	1118	131	19	int:YWHAQ
Interaction	HSPA7 interactions	ARPC1B UBE2H PAK1 PRKCG PRKCI	1.13e-04	73	131	5	int:HSPA7
Interaction	POU5F1 interactions	FLNA WDR33 MUC16 SALL4 ZNF217 ECPAS FANCD2 SETDB1 UBR5 CSNK2A1 AFDN MGA CNOT1	1.14e-04	584	131	13	int:POU5F1
Interaction	SNX27 interactions	SORBS2 ERCC5 NUP85 SEC24A CAMSAP3 WDR26 UBE2H PAK1 ANKRD28 AFDN MAP3K7 MGA	1.24e-04	509	131	12	int:SNX27
Interaction	CD5L interactions	FANCD2 CD40LG	1.25e-04	3	131	2	int:CD5L
Interaction	PCDH18 interactions	FANCD2 CSNK2A1 CSNK2A3	1.41e-04	16	131	3	int:PCDH18
Interaction	GID8 interactions	ASH1L PTPN21 WDR26 UBE2H TIGD5 TBL1X	1.53e-04	123	131	6	int:GID8
Interaction	PARD6A interactions	ASH1L PTPN21 UBE2H PRKCG PRKCI	1.55e-04	78	131	5	int:PARD6A
Interaction	PRPF40A interactions	DDX42 GATA3 FANCD2 SF3B1 UBE2H UBR5 TMEM132D NKAPD1 CSNK2A1 SRRM2 KDF1	1.62e-04	446	131	11	int:PRPF40A
Interaction	ARPC5L interactions	FLNA USP22 ARPC1B FANCD2 PAK1	1.65e-04	79	131	5	int:ARPC5L
Interaction	WDR26 interactions	FLNA PTPN21 ECPAS WDR26 UBE2H PAK1 TIGD5	1.72e-04	179	131	7	int:WDR26
Interaction	TMPRSS4 interactions	HLA-DQB1 ECPAS ANKLE2 FANCD2 LRIG3 SLC9A1 TELO2 MTHFR SYNE2	2.16e-04	314	131	9	int:TMPRSS4
Interaction	PAGE4 interactions	FLNA CAMSAP3 WDR26 SF3B1 ANKRD28 SRRM2 MAP3K7 MGA	2.53e-04	253	131	8	int:PAGE4
GeneFamily	CTAGE family	CTAGE6 MIA2 CTAGE15	5.92e-05	15	94	3	907
GeneFamily	Glycine receptors	GLRA3 GLRA1	2.65e-04	5	94	2	868
GeneFamily	Zinc fingers CXXC-type\|Methyl-CpG binding domain containing	SETDB1 BAZ2A	1.43e-03	11	94	2	1025
GeneFamily	Low density lipoprotein receptors	LRP1B LRP6	2.01e-03	13	94	2	634
GeneFamily	Ankyrin repeat domain containing\|FERM domain containing	PTPN21 PLEKHH1 TLN2	2.24e-03	50	94	3	1293
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	GATA2 GATA3	2.69e-03	15	94	2	82
GeneFamily	T-boxes	TBX19 MGA	3.88e-03	18	94	2	766
Coexpression	LAKE_ADULT_KIDNEY_C3_PROXIMAL_TUBULE_EPITHELIAL_CELLS_S1_S2	PRUNE2 SORBS2 ZBTB16 ARHGEF28 ASH1L SNX29 SETBP1 SYNE2 TLN2 AFDN SRRM2	1.83e-08	221	133	11	M39222
Coexpression	DACOSTA_UV_RESPONSE_VIA_ERCC3_DN	NCOA2 TCF12 SEC24A DDX42 USP24 ANKLE2 MEIS2 SETDB1 HEG1 MIA2 UBR5 CSNK2A1 SYNE2 ANKRD28 PRKCI PLCB4 TBL1X	1.66e-06	856	133	17	M4500
Coexpression	GSE4984_LPS_VS_VEHICLE_CTRL_TREATED_DC_DN	NCOA2 ZBTB16 ECPAS TBX19 NF1 CD40LG TNFAIP3 CNOT1	8.05e-06	198	133	8	M6511
Coexpression	HE_LIM_SUN_FETAL_LUNG_C7_PCP4_POS_NEURON_CELL	PRUNE2 ARHGEF28 GATA3 SEPTIN3 ELAVL2	8.08e-06	54	133	5	M45797
Coexpression	RODRIGUES_THYROID_CARCINOMA_POORLY_DIFFERENTIATED_DN	SORBS2 WDR33 PLEKHH1 LRIG3 NF1 MIA2 SHANK2 NKAPD1 CSNK2A1 SYNE2 PAK1 ANKRD28 AFDN TNFAIP3 SRRM2	1.55e-05	807	133	15	M16651
Coexpression	DESCARTES_FETAL_INTESTINE_CHROMAFFIN_CELLS	GLRA3 SSTR2 LRP1B ADGRG4 TMEM132D RAB3B	2.47e-05	113	133	6	M40208
Coexpression	LAZARO_GENETIC_MOUSE_MODEL_HIGH_GRADE_LARGE_CELL_NEUROENDOCRINE_LUNG_CARCINOMA_UP	CASP8AP2 TICRR UBE2C RAET1G CDC45 FANCD2 ULBP2 ANKRD28 RAET1L AMMECR1	4.07e-05	402	133	10	MM454
Coexpression	EPPERT_LSC_R	SETDB1 NF1 UBR5 MAP3K7	6.11e-05	42	133	4	M19230
Coexpression	GSE13484_UNSTIM_VS_3H_YF17D_VACCINE_STIM_PBMC_UP	CASP8AP2 ZBTB16 TCF12 DDX42 SNX29 CD40LG PCSK7	7.26e-05	199	133	7	M3257
Coexpression	STREICHER_LSM1_TARGETS_UP	GATA2 GATA3 CDC45 PLCB4	7.35e-05	44	133	4	M15031
Coexpression	GSE43955_10H_VS_30H_ACT_CD4_TCELL_WITH_TGFB_IL6_UP	NCOA2 USP22 CDC45 UBE2H MTHFR PCSK7 TIGD5	7.49e-05	200	133	7	M9696
Coexpression	GSE17721_PAM3CSK4_VS_GADIQUIMOD_2H_BMDC_UP	GATA3 DSCAML1 BAZ2A CBY2 AEBP2 SDS ADGRD1	7.49e-05	200	133	7	M3964
Coexpression	GSE5589_LPS_AND_IL10_VS_LPS_AND_IL6_STIM_MACROPHAGE_45MIN_UP	TCF12 WDR26 NF1 ANKRD28 PRKCI CEP131 OXSM	7.49e-05	200	133	7	M6613
Coexpression	HAHTOLA_MYCOSIS_FUNGOIDES_DN	FLNA ZBTB16 HLA-DQB1	8.24e-05	17	133	3	M12073
CoexpressionAtlas	FacebaseRNAseq_e10.5_Medial Nasal Eminence_top-relative-expression-ranked_500	MPO NCOA2 TICRR GATA2 GATA3 SALL4 SNX29 GPR179 FANCD2 CBY2 MROH7 IGSF1 RAB3B	9.66e-06	488	130	13	Facebase_RNAseq_e10.5_Medial Nasal Eminence_500
CoexpressionAtlas	FacebaseRNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_top-relative-expression-ranked_1000	MPO NCOA2 CASP8AP2 SORBS2 ZBTB16 CAMSAP3 SALL4 MEIS2 SEPTIN3 UBR5 SETBP1 WFIKKN2 SYNE2 PAK1 ELAVL2 ANKRD28 CHD6 IGSF1	3.12e-05	983	130	18	Facebase_RNAseq_e10.5_Neural Epithelium Overlying Lateral Eminence_1000
ToppCell	Brain_organoid-organoid_Kanton_Nature\|Brain_organoid / Sample Type, Dataset, Time_group, and Cell type.	CASP8AP2 ZBTB16 ADA2 SEPTIN3 BAZ2A SYNE2 AFDN CHD6 SRRM2	5.18e-09	185	134	9	857c7ca8493e91ef1d0078ddafd6082020f9b169
ToppCell	human_hepatoblastoma-Tumor_cells\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARHGEF28 LRIG3 UBR5 CSNK2A1 LRP6 AFDN CHD6 SRRM2 ADGRD1	7.17e-09	192	134	9	916fbec1c7ab7969bda711886ac88e877e30c280
ToppCell	LPS_IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	USP22 ASH1L MEIS2 HEG1 ZNF608 UBR5 SYNE2 AFDN PLCB4	1.02e-08	200	134	9	dccec522ab0d7fff62ad6273b02aa9022dbbb8eb
ToppCell	droplet-Lung-3m-Hematologic-myeloid-myeloid_dendritic_cell-proliferating_dendritic\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	TICRR UBE2C CDC45 FANCD2 SEPTIN3 PAK1 AMMECR1 SLC24A1	6.40e-08	176	134	8	581045e61cdcdfa85701343d1a7c0a72a36606a7
ToppCell	renal_cortex_nuclei\|World / Celltypes from Cells and Nuclei per compartment and clinical group	SORBS2 ZBTB16 TCF12 ASH1L SNX29 SHANK2 SETBP1 SYNE2	1.25e-07	192	134	8	e8cc4d08fcfceeab75a02558817e4ccd7dbafe3a
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn-38\|World / Primary Cells by Cluster	SORBS2 SSTR2 MEIS2 ZNF608 SETBP1 SYNE2 ELAVL2 PLCB4	1.47e-07	196	134	8	38da0751941adca650fe9b383d9f343153978eb5
ToppCell	Neuron-Postmitotic-Excitatory_Neuron_-IPC/newborn\|World / Primary Cells by Cluster	SORBS2 SSTR2 MEIS2 ZNF608 SETBP1 SYNE2 ELAVL2 PLCB4	1.47e-07	196	134	8	721650a08d260faf530dbd52d4e9275d27f3bac2
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Gen_Cap\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	USP22 GATA2 MEIS2 HEG1 ZNF608 SYNE2 AFDN PLCB4	1.71e-07	200	134	8	a2b9d1cd291d17abddc3ee2e242121412c864b8b
ToppCell	droplet-Lung-nan-3m-Myeloid-dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR DSCAML1 CDC45 FANCD2 SEPTIN3 PAK1 SLC24A1	4.01e-07	152	134	7	77b319f594d5e4df29034bbf69c7490076f89dd3
ToppCell	droplet-Lung-nan-3m-Myeloid-Proliferating_Dendritic\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TICRR ZNF169 CDC45 FANCD2 SEPTIN3 PAK1 SLC24A1	5.67e-07	160	134	7	8a7a73b0ee1877fe02d47f745d36ae2858b529e1
ToppCell	343B-Myeloid-Dendritic-cDC_proliferating_2\|343B / Donor, Lineage, Cell class and subclass (all cells)	MPO TICRR UBE2C CDC45 FANCD2 PRKCG HCK	9.96e-07	174	134	7	a75ba49ccea6bd3d78ada1092b46deb5202c58a5
ToppCell	3'-Child09-12-SmallIntestine-Hematopoietic-Myeloid-cDC1\|Child09-12 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HLA-DQB1 ADA2 DSCAML1 ARPC1B PAK1 HCK SDS	1.39e-06	183	134	7	661bfc8f5f683b0f4c12bdd359e67c513b181678
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 SNX29 SHANK2 TMEM132D PRKCI TBL1X	1.67e-06	188	134	7	63a4b25a0a6e05f80f1a6dd91b817f3cf49e6b68
ToppCell	LPS_only-Endothelial-Endothelial-Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB16 MEIS2 HEG1 ZNF608 AFDN PLCB4 AMMECR1	1.79e-06	190	134	7	474cbbab8f3b0a6881fa6c92edb78e43999f9ab0
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SORBS2 SSTR2 MEIS2 SYNE2 ELAVL2 AFDN PLCB4	1.99e-06	193	134	7	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	SORBS2 SSTR2 MEIS2 SYNE2 ELAVL2 AFDN PLCB4	1.99e-06	193	134	7	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	Bronchial-NucSeq-Stromal-Myofibroblastic-Muscle_smooth_airway_ASM\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	ZNF280A PRUNE2 FLNA LRP1B KCNQ5 ELAVL2 PLCB4	2.20e-06	196	134	7	9830fb3da7a60f65ad463e9054bb77c06b025e4d
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 TCF12 ARHGEF28 NF1 SHANK2 UBR5 PLCB4	2.43e-06	199	134	7	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA-Endothelial-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 ZNF608 SYNE2 AFDN PLCB4	2.52e-06	200	134	7	72ea9882a8ed26fa1534aeb6ba0d1897dccc20c5
ToppCell	LPS_IL1RA-Endothelial\|LPS_IL1RA / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 ZNF608 SYNE2 AFDN PLCB4	2.52e-06	200	134	7	5c092b2ecc081b5d04476c56333c338cd89ab984
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 ZNF608 SYNE2 AFDN PLCB4	2.52e-06	200	134	7	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	SORBS2 SSTR2 MEIS2 SYNE2 ELAVL2 AFDN PLCB4	2.52e-06	200	134	7	3d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 ZNF608 SYNE2 AFDN PLCB4	2.52e-06	200	134	7	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SORBS2 ARHGEF28 MUC16 PLEKHH1 LRIG3 SHANK2 PLCB4	2.52e-06	200	134	7	85c0f038bcfb42669dca2b80273b0f8a1421405e
ToppCell	COVID-19-kidney-PEC\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 ARHGEF28 DSCAML1 SHANK2 TMEM132D SYNE2	1.20e-05	168	134	6	a086c306be430adf0632ba53e98cd8014d2de330
ToppCell	normal-na-Lymphocytic_NK-natural_killer_cell-male\|normal / PBMC cell types (v2) per disease, treatment status, and sex	ZBTB16 GATA2 SYNE2 ULBP2 TLN2 CATSPERG	1.33e-05	171	134	6	d339840626211a7bf1a9eb8f14d6c9509ab05e1c
ToppCell	T_cells-CD56_bright_CD16-_NK_cells\|World / Immune cells in Kidney/Urine in Lupus Nephritis	ZBTB16 GATA2 RYR3 MIA2 PLCB4 ADGRD1	1.37e-05	172	134	6	980e8b9e1ceeb0dec9eb9ef95c139e5ffe99b6e4
ToppCell	droplet-Liver-LIVER_NPC-30m-Endothelial-nan\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CASP8AP2 NXPE4 ANKRD28 PLCB4 MGA TMEM255A	1.72e-05	179	134	6	025d414ec88d5680d99c8173e70ee3bb0b694f74
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_FAM95C\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SSTR2 MEIS2 RYR3 PRKCG PLCB4 RAB3B	1.72e-05	179	134	6	f65889bf1e41396979cce44a5e63f49dea2bbd9b
ToppCell	tumor_Lymph_Node_/_Brain-Fibroblasts-Smooth_muscle_cells\|Fibroblasts / Location, Cell class and cell subclass	PRUNE2 LRP1B ZNF852 ELAVL2 SLC24A1 CSNK2A3	1.72e-05	179	134	6	83506e00fe99b6450efd2f13f716926a0a4b03cd
ToppCell	10x5'-Liver-Lymphocytic_T_CD4-T_CD4/CD8\|Liver / Manually curated celltypes from each tissue	TCF12 ASH1L UBR5 SYNE2 PCSK7 TNFAIP3	1.83e-05	181	134	6	f2315414e714ac86211546a935660c4be6e85f1b
ToppCell	COPD-Myeloid-Mast\|World / Disease state, Lineage and Cell class	GATA2 MEIS2 RYR3 HEG1 PAK1 TNFAIP3	1.89e-05	182	134	6	68a1e7b804f309bfd6c23d65fad20a9a962712ae
ToppCell	RA-13._Vascular_Smooth_Muscle\|RA / Chamber and Cluster_Paper	PRUNE2 FLNA ARHGEF28 KCNQ5 PLCB4 TBL1X	1.95e-05	183	134	6	818fd886e0188091310825f9145fa53328f2c979
ToppCell	primary_auditory_cortex_(A1C)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2\|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SSTR2 MEIS2 RYR3 PRKCG PLCB4 RAB3B	1.95e-05	183	134	6	65f2a5895d166189a095cf7ea9dda171f0419b08
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SORBS2 GATA2 CTAGE6 MEIS2 HEG1 PLCB4	1.95e-05	183	134	6	c1297d8eddfc7132e84ceef14f01b6281f9d0f6a
ToppCell	droplet-Lung-30m-Endothelial-arterial_endothelial-pulmonary_artery_endothelial_cell-pulmonary_artery_endothelial_cell_l27\|30m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	SORBS2 ARHGEF28 PLEKHH1 ARHGAP44 PLCB4 CATSPERG	1.95e-05	183	134	6	351d575339038bd4a66f408da518c567444208e8
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL4 LRP1B DSCAML1 RYR3 TLN2 DNAH9	2.01e-05	184	134	6	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL4 LRP1B DSCAML1 RYR3 TLN2 DNAH9	2.01e-05	184	134	6	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	wk_08-11-Epithelial-PNS-PCP4+_neuron\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	SORBS2 ARHGEF28 GATA3 SEPTIN3 KCNQ5 ELAVL2	2.01e-05	184	134	6	eac2a9089913f33a961ba11519b53645790f2056
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SALL4 LRP1B DSCAML1 RYR3 TLN2 DNAH9	2.01e-05	184	134	6	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2/Club-like_(AT2/Club-like)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SHANK2 KCNQ5 ZNF608 TMEM132D ARHGAP44 PRKCI	2.13e-05	186	134	6	2ea5ff14861e5f91d0e6a5767c403a24045d715c
ToppCell	3'-Pediatric_IBD-SmallIntestine-Hematopoietic-Myeloid-cDC2\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP6V1B2 HLA-DQB1 ADA2 ARPC1B PAK1 HCK	2.13e-05	186	134	6	44785bd171f424ad61437275026439fae3cb8d8c
ToppCell	droplet-Heart-nan-3m-Endothelial\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	GATA2 HEG1 ZNF608 SYNE2 AFDN PLCB4	2.13e-05	186	134	6	0ae5fbe9f210cb25092394267e1d3d6ed05627b8
ToppCell	368C-Myeloid-Dendritic-cDC_proliferating_1\|Dendritic / Donor, Lineage, Cell class and subclass (all cells)	PRUNE2 UBE2C MEIS2 CDC45 HEG1 CCDC136	2.13e-05	186	134	6	5cadab3271fce9ab6da3d7ba9827b8a221cac166
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 SORBS2 ZNF608 SYNE2 TLN2 PLCB4	2.13e-05	186	134	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	Adult-Endothelial-endothelial_cell_of_artery\|Adult / Lineage, Cell type, age group and donor	GATA2 MEIS2 RYR3 HEG1 SETBP1 PLCB4	2.13e-05	186	134	6	2d1c4ea2e401db89971582ee54618a8b0c81b8ac
ToppCell	5'-Adult-LymphNode-Hematopoietic-Myeloid-Macrophages\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ATP6V1B2 ADA2 ARPC1B CSNK2A3 HCK SDS	2.20e-05	187	134	6	00930e407beaa337f72533a69f32d150faad8b9a
ToppCell	COVID-19-kidney\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 ARHGEF28 LRP1B DSCAML1 SHANK2 SYNE2	2.20e-05	187	134	6	d23aae9419d460b78b1d4092d7acd9108a47cfbe
ToppCell	10x5'-GI_small-bowel-Lymphocytic_T_CD4-T_CD4/CD8\|GI_small-bowel / Manually curated celltypes from each tissue	ASH1L USP24 NF1 UBE2H SYNE2 TNFAIP3	2.26e-05	188	134	6	ab9b725d6e0cdab8e9ddda6dee09e14730e9a578
ToppCell	P07-Endothelial-large_vessel_endothelial_cell-endothelial_cell_of_artery\|P07 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	ARHGEF28 GATA2 GATA3 ARPC1B MEIS2 HEG1	2.26e-05	188	134	6	5bc1537e079c7435196c163bff5f639ea392a33a
ToppCell	LA-13._Vascular_Smooth_Muscle\|LA / Chamber and Cluster_Paper	PRUNE2 FLNA ARHGEF28 RYR3 KCNQ5 PLCB4	2.26e-05	188	134	6	34e1b074a3995aa46ab194eb45115d76d1a5514d
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-C\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ATP6V0C SSTR2 MEIS2 SHANK2 ELAVL2 AFDN	2.26e-05	188	134	6	e239bcdbd210a398a5850cb6fbf171d402f45a4f
ToppCell	3'_v3-lymph-node_spleen-Myeloid_Dendritic-Cycling_Dendritic\|lymph-node_spleen / Manually curated celltypes from each tissue	UBE2C CDC45 PLEKHH1 SEPTIN3 PAK1 AADAT	2.26e-05	188	134	6	723348a1836a074e068320cb736ce6a953e0038f
ToppCell	LA-13._Vascular_Smooth_Muscle\|World / Chamber and Cluster_Paper	PRUNE2 FLNA ARHGEF28 RYR3 KCNQ5 PLCB4	2.33e-05	189	134	6	6b3e88751b95fc2173f2c3d5061ed632d0c5f01c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANKLE2 LRP1B DSCAML1 UBE2H SYNE2 PLCB4	2.33e-05	189	134	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	ANKLE2 LRP1B DSCAML1 UBE2H SYNE2 PLCB4	2.33e-05	189	134	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	Fetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	SALL4 SHANK2 ZNF608 ARHGAP44 AEBP2 PRKCI	2.40e-05	190	134	6	8aea807a2bcf0b653b4de6202b6ecb0f0683cc2e
ToppCell	COPD-Myeloid-Mast\|Myeloid / Disease state, Lineage and Cell class	SH2D3A GATA2 MEIS2 RYR3 HEG1 PAK1	2.40e-05	190	134	6	379dbac19110b76079a7a53209569e060a852acb
ToppCell	3'_v3-GI_small-bowel-Myeloid_Mac-Cycling_Myeloid-Mac\|GI_small-bowel / Manually curated celltypes from each tissue	TICRR HLA-DQB1 UBE2C CDC45 HCK SDS	2.47e-05	191	134	6	c3944332c5226b0113f8aa9ac07837b755606c6c
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-IPC_like-IPCs\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	SSTR2 MEIS2 SYNE2 ELAVL2 AFDN PLCB4	2.55e-05	192	134	6	bd91bf0ceeac49dc5a18aa2e401244db0ca596ae
ToppCell	Brain_organoid-organoid_Velasco_nature-6_mon-IPC_like\|6_mon / Sample Type, Dataset, Time_group, and Cell type.	SSTR2 MEIS2 SYNE2 ELAVL2 AFDN PLCB4	2.55e-05	192	134	6	18fbf485ad762ba7a9ac3e19bad136b0cf3af3c5
ToppCell	Substantia_nigra\|World / BrainAtlas - Mouse McCarroll V32	GATA3 PLEKHH1 GLRA1 IGSF1 SLC4A9	2.57e-05	115	134	5	18174b8d57d444fab1e9d2b13d22939c83c958e0
ToppCell	wk_15-18-Hematologic-Myeloid-DC1\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	HLA-DQB1 ADA2 ARPC1B SEPTIN3 PAK1 HCK	2.62e-05	193	134	6	df9a4a459af51c2040ad832b580c333a135e374e
ToppCell	human_hepatoblastoma-Tumor_cells\|human_hepatoblastoma / Sample and Cell Type and Tumor Cluster (all cells)	SORBS2 ARHGEF28 SHANK2 LRP6 AFDN CHD6	2.62e-05	193	134	6	503a979328c68b096680b71359a26f02fafdff35
ToppCell	P15-Endothelial-large_vessel_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	SORBS2 GATA3 ARPC1B MEIS2 HEG1 PLCB4	2.62e-05	193	134	6	5f9a7cd5f8eb9ac294cdb50518fedf872f3f78f5
ToppCell	human_hepatoblastoma\|World / Sample and Cell Type and Tumor Cluster (all cells)	ARHGEF28 UBR5 AFDN CHD6 SRRM2 ADGRD1	2.62e-05	193	134	6	e6a688bc834f845ff64dae1be64f073eec5091a1
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 ARHGEF28 SNX29 SHANK2 SYNE2 AFDN	2.70e-05	194	134	6	7002937e8903e037332a215d00fbc7c7843b33f2
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic-neutrophil\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARHGEF28 MUC16 LRP1B RYR3 TNFAIP3 DNAH9	2.78e-05	195	134	6	d3755929ebbbf5e3afde44281e9056ddb614a291
ToppCell	Smart-seq2-spleen_(Smart-seq2)-myeloid-myeloid_granulocytic\|spleen_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ARHGEF28 MUC16 LRP1B RYR3 TNFAIP3 DNAH9	2.78e-05	195	134	6	19853c654ac64b3ae3bc99841c6cb29c8aaba85c
ToppCell	renal_medulla_nuclei-CKD+DKD_normotensive-Epithelial\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ARHGEF28 LRP1B DSCAML1 SNX29 SHANK2 AFDN	2.78e-05	195	134	6	6477e6e7be5bd8eb99119a12ae16334ccddecd43
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	ECPAS CDC45 SEPTIN3 PAK1 RAET1L	2.90e-05	118	134	5	f0f40a0165156e3fc1584480b473b0e84e10d2cc
ToppCell	lymphoid-T_cell-unlabelled(multiplets)\|T_cell / Lineage, cell class and subclass	FLNA ZBTB16 GATA3 SURF4 TNFAIP3 CNOT1	2.94e-05	197	134	6	f215435aee15f0ed254104bfd55670144b6d2ac3
ToppCell	NS-moderate-d_07-13-Myeloid-Non-resident_Macrophage\|d_07-13 / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	FLNA ATP6V1B2 ADA2 TNFAIP3 HCK SDS	2.94e-05	197	134	6	774a5053f43ac7d614c127ae7363d32a3a194f63
ToppCell	lymphoid-T_cell-unlabelled(multiplets)\|lymphoid / Lineage, cell class and subclass	FLNA ZBTB16 GATA3 SURF4 TNFAIP3 CNOT1	2.94e-05	197	134	6	a224c0a010489ad043bd2ad1385eef33c3b6b792
ToppCell	PBMC-Mild-Myeloid-cDC-cDC-cDC_12\|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	ECPAS CDC45 SEPTIN3 PAK1 RAET1L	3.02e-05	119	134	5	a6b359e7aafcc197f53eb5e19c3a905bc09497bb
ToppCell	10x3'2.3-week_14-16-Myeloid_neutrophil-granulo-neutrophil-myelocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	FLNA ATP6V1B2 ADA2 ARPC1B PAK1 HCK	3.03e-05	198	134	6	c7c5865395992131d0766a03c9c63bad9196b02f
ToppCell	Primary_Motor_Cortex_(M1)-Neuronal\|Primary_Motor_Cortex_(M1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	SORBS2 SHANK2 KCNQ5 SETBP1 ARHGAP44 PAK1	3.03e-05	198	134	6	4ca5ff320905ab4ff60ed90a5522227c782142a6
ToppCell	Parenchymal-NucSeq\|Parenchymal / Cell types per location group and 10X technology with lineage, and cell group designations	NCOA2 ZBTB16 TCF12 NF1 SHANK2 ARHGAP44	3.03e-05	198	134	6	1996373bdccc55aac347d349bd22f6aad6d0c668
ToppCell	lymphoid-NK_cell-NK_cell\|NK_cell / Lineage, cell class and subclass	USP22 HLA-DQB1 BAZ2A SURF4 SYNE2 CNOT1	3.11e-05	199	134	6	945fbf5845403a8b22d04963f50ad69c414b6153
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPO FLNA ATP6V1B2 ADA2 ARPC1B PAK1	3.11e-05	199	134	6	5caaf66b6cddcc8f0d0aee3c9ba80d02075e87e5
ToppCell	10x5'v1-week_14-16-Myeloid_monocytic-monocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	MPO FLNA ATP6V1B2 ADA2 ARPC1B PAK1	3.11e-05	199	134	6	7f5d47e49776114d9f4a42017fead9eeb415a94c
ToppCell	11.5-Airway-Mesenchymal-Airway_Smooth_Muscle\|Airway / Age, Tissue, Lineage and Cell class	FLNA TCF12 WFIKKN2 IGSF1 TMEM255A ADGRD1	3.11e-05	199	134	6	1a8c77d241bd817a195e1532fd25f51358cb1ff1
ToppCell	Tracheal\|World / Cell types per location group and 10X technology with lineage, and cell group designations	SORBS2 ARHGEF28 MUC16 MEIS2 LRIG3 PLCB4	3.20e-05	200	134	6	682960e28542a3d6c119047cd0131941932cfdea
ToppCell	Bronchial-NucSeq-Epithelial-Epi_submucosal-gland-SMG_Serous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	SORBS2 ARHGEF28 MEIS2 PLEKHH1 LRIG3 SHANK2	3.20e-05	200	134	6	030efc36bbb848da31b0db3f74d46aac9c79cc9b
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Artery\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 SYNE2 AFDN PLCB4	3.20e-05	200	134	6	77ae679c35d3b9e2b620f34129f3a8d47e922c65
ToppCell	5'-Parenchyma_lung-Immune_Myeloid\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ATP6V1B2 ATP6V0C HLA-DQB1 ADA2 ARPC1B HCK	3.20e-05	200	134	6	37a091925b214a0befea59b711ab92809a7b93c8
ToppCell	LPS_IL1RA_TNF-Endothelial-Endothelial-Gen_Cap\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 ZNF608 AFDN PLCB4	3.20e-05	200	134	6	b2d4e6f3e8e4da62e6b02758ab2ed8f505269f9a
ToppCell	COVID-19\|World / Disease, condition lineage and cell class	FLNA SF3B1 SYNE2 TNFAIP3 SRRM2 CNOT1	3.20e-05	200	134	6	7dec470c379cd89f05a0f37c8628b21f136e52f0
ToppCell	NS-control\|NS / Location, Severity, dps_group, Lineage and Cell class of Upper airway (combined)	SORBS2 ARHGEF28 MUC16 MEIS2 SYNE2 AFDN	3.20e-05	200	134	6	ecbe89ff95d046155b984c8c150e0b9e7278f839
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	GATA2 LRP1B MEIS2 HEG1 TLN2 PLCB4	3.20e-05	200	134	6	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	LPS_anti-TNF-Endothelial-Endothelial-Artery\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	GATA2 MEIS2 HEG1 SYNE2 AFDN PLCB4	3.20e-05	200	134	6	b1ff8d61b567f85006d6d20093f9c803b6d34674
ToppCell	3'_v3-bone_marrow-Lymphocytic_T_CD4-T_CD4/CD8\|bone_marrow / Manually curated celltypes from each tissue	ASH1L SSTR2 SYNE2 PCSK7 ELAVL2	3.28e-05	121	134	5	19333a660800b583fa27b495c1f7828e6636a257
ToppCell	LPS-IL1RA-Endothelial-Epi-like-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SALL4 STEAP2 DSCAML1 SHANK2 TMEM132D	4.13e-05	127	134	5	6b24630978eb0772b4cd3bf59e5bc4390be47619
ToppCell	primary_visual_cortex-Neuronal-glutamatergic_neuron-L6_CT-L6_CT_VISp_Nxph2_Wls\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	LRP1B MEIS2 FANCD2 PAK1 PRKCG	4.62e-05	130	134	5	05d5a73acf1d7f75a79876b1a06d27c74a89b8a4
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 RYR3 AMMECR1 CCDC136 TMEM255A	4.97e-05	132	134	5	46c80eab16a70da9f363a9fbdf50bccab0b287d7
ToppCell	LPS-IL1RA+antiTNF-Unknown\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 RYR3 AMMECR1 CCDC136 TMEM255A	4.97e-05	132	134	5	a022c3c41654166cb106f27dc54fa88e8c40f898
ToppCell	TCGA-Bladder-Solid_Tissue_Normal-Urothelial_normal_tissue-Urothelial_normal_tissue-2\|TCGA-Bladder / Sample_Type by Project: Shred V9	PRUNE2 ZBTB16 ADGRG4 RYR3 ADGRD1	6.79e-05	141	134	5	1baa054c2ae3b446d1954244b7fbf8af824ef345
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 DSCAML1 SNX29 TMEM132D SETBP1	7.26e-05	143	134	5	7a7a9829ba63468c9745904d9e993590051207ab
ToppCell	facs-Brain_Myeloid-Cortex-24m-Myeloid-macrophage\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FLNA ZBTB16 NXPE4 HEG1 RAB3B	1.03e-04	154	134	5	1e088b0d4a44267f46a9b643f46a1aba784686b1
ToppCell	LPS-IL1RA+antiTNF-Unknown-Endothelial-Myofibroblast\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	PRUNE2 RYR3 CEP131 OXSM CCDC136	1.03e-04	154	134	5	16fdafb5c64d2db321554f87129a962d113f1668
Drug	sevoflurane	GLRA3 RYR3 GLRA1 PRKCG PRKCI PLCB4 TNFAIP3	2.80e-06	105	133	7	CID000005206
Drug	Trichostatin A, Streptomyces sp.; Down 200; 0.1uM; MCF7; HT_HG-U133A_EA	NCOA2 USP22 USP24 GATA3 ECPAS SETDB1 RPRD2 SRRM2	7.27e-06	170	133	8	1050_DN
Drug	3-Acetamidocoumarin [779-30-6]; Up 200; 19.6uM; HL60; HT_HG-U133A	SH2D3A ADA2 SHANK2 BAZ2A TLN2 AFDN SLC24A1 SDS	2.04e-05	196	133	8	2941_UP
Drug	Folic acid [59-30-3]; Down 200; 9uM; MCF7; HT_HG-U133A	GATA2 PTPN21 TBX19 TELO2 BAZ2A ARHGAP44 LRP6 TLN2	2.12e-05	197	133	8	7201_DN
Drug	Meclocycline sulfosalicylate [73816-42-9]; Up 200; 5.8uM; PC3; HT_HG-U133A	PRUNE2 GLRA3 PTPN21 NF1 CD40LG PAK1 TLN2 SDS	2.20e-05	198	133	8	6637_UP
Drug	Cinnarizine [298-57-7]; Down 200; 10.8uM; MCF7; HT_HG-U133A	NCOA2 TBX19 NF1 MIA2 MTOR ANKRD28 RPRD2 SLC24A1	2.20e-05	198	133	8	7174_DN
Drug	Dimenhydrinate [523-87-5]; Up 200; 8.6uM; PC3; HT_HG-U133A	PRUNE2 WDR33 PTPN21 MIA2 ERAP2 MTHFR SRRM2 RAB3B	2.20e-05	198	133	8	6352_UP
Drug	Propantheline bromide [50-34-0]; Down 200; 9uM; HL60; HT_HG-U133A	PRUNE2 GATA2 HEG1 NF1 ERAP2 PAK1 PCSK7 LRP6	2.20e-05	198	133	8	3013_DN
Drug	Disopyramide [3737-09-5]; Up 200; 11.8uM; MCF7; HT_HG-U133A	ZNF821 GATA2 ECPAS NF1 TELO2 PCSK7 LRP6 SRRM2	2.20e-05	198	133	8	7035_UP
Disease	Prostatic Neoplasms	MPO NCOA2 ZBTB16 ASH1L LRP1B SETDB1 SF3B1 BAZ2A MTHFR SURF4 RPRD2 CHD6 MAP3K7 MGA	7.37e-07	616	132	14	C0033578
Disease	Malignant neoplasm of prostate	MPO NCOA2 ZBTB16 ASH1L LRP1B SETDB1 SF3B1 BAZ2A MTHFR SURF4 RPRD2 CHD6 MAP3K7 MGA	7.37e-07	616	132	14	C0376358
Disease	D dimer measurement	ARHGEF28 ELAVL2 CATSPERG OR4C5	9.58e-06	30	132	4	EFO_0004507
Disease	Frontometaphyseal dysplasia	FLNA MAP3K7	1.99e-05	2	132	2	C0265293
Disease	level of UL16-binding protein 6 in blood serum	ULBP2 RAET1L	1.99e-05	2	132	2	OBA_2043185
Disease	FRONTOMETAPHYSEAL DYSPLASIA 1	FLNA MAP3K7	1.99e-05	2	132	2	C4281559
Disease	Frontometaphyseal dysplasia	FLNA MAP3K7	1.99e-05	2	132	2	cv:C0265293
Disease	Lymphoma, Follicular, Grade 2	ATP6V1B2 MTHFR TNFAIP3	3.83e-05	15	132	3	C1956132
Disease	Lymphoma, Follicular, Grade 3	ATP6V1B2 MTHFR TNFAIP3	3.83e-05	15	132	3	C1956131
Disease	Lymphoma, Follicular, Grade 1	ATP6V1B2 MTHFR TNFAIP3	3.83e-05	15	132	3	C1956130
Disease	Lymphoma, Large-Cell, Follicular	ATP6V1B2 MTHFR TNFAIP3	3.83e-05	15	132	3	C0079745
Disease	Lymphoma, Small Cleaved-Cell, Follicular	ATP6V1B2 MTHFR TNFAIP3	3.83e-05	15	132	3	C0079765
Disease	Lymphoma, Mixed-Cell, Follicular	ATP6V1B2 MTHFR TNFAIP3	3.83e-05	15	132	3	C0079758
Disease	acute myeloid leukemia (is_implicated_in)	NCOA2 HLA-DQB1 GATA2 NF1 MTHFR	3.86e-05	84	132	5	DOID:9119 (is_implicated_in)
Disease	Juvenile Myelomonocytic Leukemia	GATA2 NF1 SETBP1	8.05e-05	19	132	3	C0349639
Disease	Lymphoma, Follicular	ATP6V1B2 MTHFR TNFAIP3	9.44e-05	20	132	3	C0024301
Disease	Malignant neoplasm of breast	NCOA2 FLNA UBE2C SH2D3A GATA3 NF1 MIA2 MTOR MTHFR SETBP1 SYNE2 PAK1 MROH7 OXSM DNAH9	9.58e-05	1074	132	15	C0006142
Disease	melanoma	ERCC5 LRP1B TRAPPC1 SETDB1 NF1 PAK1 PLCB4	1.32e-04	248	132	7	C0025202
Disease	Morbilliform Drug Reaction	MPO HLA-DQB1 MTHFR	1.45e-04	23	132	3	C0406537
Disease	Drug Eruptions	MPO HLA-DQB1 MTHFR	1.45e-04	23	132	3	C0011609
Disease	hepatocellular carcinoma (is_implicated_in)	MPO HLA-DQB1 LRP1B RYR3 SF3B1 MTHFR	1.69e-04	181	132	6	DOID:684 (is_implicated_in)
Disease	Intellectual Disability	ASH1L WDR26 MEIS2 NF1 SHANK2 KCNQ5 MTOR SETBP1 PRKCG	1.90e-04	447	132	9	C3714756
Disease	Myelodysplastic syndrome	GATA2 SF3B1	1.97e-04	5	132	2	cv:C3463824
Disease	MYELODYSPLASTIC SYNDROME	GATA2 SF3B1	1.97e-04	5	132	2	614286
Disease	MYELODYSPLASTIC SYNDROME	GATA2 FANCD2 SF3B1 SETBP1	2.36e-04	67	132	4	C3463824
Disease	Epileptic encephalopathy	FLNA RYR3 MTOR	3.25e-04	30	132	3	C0543888
Disease	myelodysplastic syndrome (is_implicated_in)	GATA2 ARPC1B SF3B1	3.25e-04	30	132	3	DOID:0050908 (is_implicated_in)
Disease	Shock, Hemorrhagic	MPO SLC9A1	4.11e-04	7	132	2	C0036982
Disease	neutrophil count	MPO PRUNE2 ZBTB16 WDR33 HLA-DQB1 ASH1L GATA2 WDR26 TBX19 SLC9A1 TELO2 ERAP2 TLN2 RPRD2 PLCB4 TNFAIP3	4.64e-04	1382	132	16	EFO_0004833
Disease	antiphospholipid syndrome (is_implicated_in)	HLA-DQB1 CD40LG	5.46e-04	8	132	2	DOID:2988 (is_implicated_in)
Disease	Uveal melanoma	SF3B1 PLCB4	5.46e-04	8	132	2	C0220633
Disease	autism spectrum disorder (implicated_via_orthology)	ZNF280A ASH1L DSCAML1 SHANK2 CHD6	6.21e-04	152	132	5	DOID:0060041 (implicated_via_orthology)
Disease	aplastic anemia (is_marker_for)	GATA2 CD40LG	7.00e-04	9	132	2	DOID:12449 (is_marker_for)
Disease	neural tube defect (implicated_via_orthology)	MTHFR LRP6	7.00e-04	9	132	2	DOID:0080074 (implicated_via_orthology)
Disease	Graves' disease (is_implicated_in)	HLA-DQB1 MTHFR CD40LG	7.11e-04	39	132	3	DOID:12361 (is_implicated_in)
Disease	Cutaneous Melanoma	ERCC5 NF1 PAK1	8.24e-04	41	132	3	C0151779
Disease	autistic disorder (is_implicated_in)	SETDB1 NF1 SHANK2	8.84e-04	42	132	3	DOID:12849 (is_implicated_in)
Disease	Inhalant adrenergic use measurement	ADAD1 HLA-DQB1 GATA3 MUC16	9.25e-04	96	132	4	EFO_0009941
Disease	liver cirrhosis (is_implicated_in)	MPO HLA-DQB1 MTHFR	9.47e-04	43	132	3	DOID:5082 (is_implicated_in)
Disease	unipolar depression	NCOA2 CASP8AP2 ATP6V1B2 ASH1L STEAP2 SNX29 SF3B1 SHANK2 KCNQ5 ZNF608 TMEM132D SYNE2 ELAVL2 CHD6	1.04e-03	1206	132	14	EFO_0003761
Disease	Leukemia, Myelocytic, Acute	GATA2 FANCD2 SF3B1 NF1 SETBP1	1.11e-03	173	132	5	C0023467
Disease	open-angle glaucoma (is_implicated_in)	MEIS2 MTHFR	1.27e-03	12	132	2	DOID:1067 (is_implicated_in)
Disease	Night blindness, congenital stationary, type 1	GPR179 SLC24A1	1.27e-03	12	132	2	C3501847
Disease	craniosynostosis (is_implicated_in)	FLNA TCF12	1.27e-03	12	132	2	DOID:2340 (is_implicated_in)
Disease	Night Blindness, Congenital Stationary, Type 1A	GPR179 SLC24A1	1.27e-03	12	132	2	C3495587
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2B (disorder)	GPR179 SLC24A1	1.27e-03	12	132	2	C1864877
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 1B	GPR179 SLC24A1	1.27e-03	12	132	2	C1850362
Disease	X-Linked Csnb	GPR179 SLC24A1	1.27e-03	12	132	2	C3711543
Disease	NIGHT BLINDNESS, CONGENITAL STATIONARY, TYPE 2A	GPR179 SLC24A1	1.27e-03	12	132	2	C1848172
Disease	Precursor B-Cell Lymphoblastic Leukemia-Lymphoma	GATA3 MGA	1.27e-03	12	132	2	C0023485
Disease	Cone-rod synaptic disorder, congenital nonprogressive	GPR179 SLC24A1	1.50e-03	13	132	2	C4041558
Disease	X-12063 measurement	LRP1B MEIS2 NF1 NKAPD1 SETBP1	1.53e-03	186	132	5	EFO_0021283
Disease	response to selective serotonin reuptake inhibitor, openness measurement	SNX29 ELAVL2	1.74e-03	14	132	2	EFO_0005658, EFO_0007914
Disease	autoimmune thrombocytopenic purpura (is_implicated_in)	HLA-DQB1 CD40LG	2.01e-03	15	132	2	DOID:8924 (is_implicated_in)
Disease	Liver carcinoma	MPO TICRR UBE2C CDC45 FANCD2 MTOR CEP131 AADAT	2.07e-03	507	132	8	C2239176
Disease	Urticaria	MPO HLA-DQB1	2.29e-03	16	132	2	C0042109
Disease	Malignant lymphoma, lymphocytic, intermediate differentiation, diffuse	UBR5 MTOR	2.29e-03	16	132	2	C0334634
Disease	sickle cell anemia (is_implicated_in)	HLA-DQB1 MTHFR	2.29e-03	16	132	2	DOID:10923 (is_implicated_in)
Disease	colon cancer (is_marker_for)	NF1 UBR5 TNFAIP3	2.37e-03	59	132	3	DOID:219 (is_marker_for)
Disease	proprotein convertase subtilisin/kexin type 7 measurement	DSCAML1 PCSK7	2.58e-03	17	132	2	EFO_0008270
Disease	high altitude adaptation	HLA-DQB1 MTHFR	2.58e-03	17	132	2	EFO_0009105
Disease	1-Methylhistidine measurement	NCOA2 SORBS2	2.58e-03	17	132	2	EFO_0021543
Disease	Moyamoya Disease	HLA-DQB1 NF1	2.58e-03	17	132	2	C0026654
Disease	Night blindness, congenital stationary	GPR179 SLC24A1	2.58e-03	17	132	2	C0339535
Disease	Sarcomatoid Renal Cell Carcinoma	LRP1B MTOR SYNE2 PAK1	2.66e-03	128	132	4	C1266043
Disease	Chromophobe Renal Cell Carcinoma	LRP1B MTOR SYNE2 PAK1	2.66e-03	128	132	4	C1266042
Disease	Collecting Duct Carcinoma of the Kidney	LRP1B MTOR SYNE2 PAK1	2.66e-03	128	132	4	C1266044
Disease	Papillary Renal Cell Carcinoma	LRP1B MTOR SYNE2 PAK1	2.66e-03	128	132	4	C1306837
Disease	Renal Cell Carcinoma	LRP1B MTOR SYNE2 PAK1	2.66e-03	128	132	4	C0007134
Disease	RS-warfarin measurement	LRP1B DSCAML1 UBE2H DNAH9	2.66e-03	128	132	4	EFO_0803325
Disease	Allergic Reaction	HLA-DQB1 MTHFR CD40LG	2.86e-03	63	132	3	C1527304
Disease	verbal-numerical reasoning measurement	NCOA2 SNX29 SEPTIN3 ELAVL2	2.89e-03	131	132	4	EFO_0008394
Disease	lupus nephritis (is_implicated_in)	MPO CD40LG	2.90e-03	18	132	2	DOID:0080162 (is_implicated_in)
Disease	Breast Carcinoma	NCOA2 FLNA UBE2C GATA3 MTOR MTHFR SETBP1 PAK1	2.97e-03	538	132	8	C0678222
Disease	carcinoma (implicated_via_orthology)	SALL4 PRKCI HCK	2.99e-03	64	132	3	DOID:305 (implicated_via_orthology)
Disease	Hypersensitivity	HLA-DQB1 MTHFR CD40LG	2.99e-03	64	132	3	C0020517
Disease	ankylosing spondylitis (is_implicated_in)	HLA-DQB1 MTHFR	3.23e-03	19	132	2	DOID:7147 (is_implicated_in)
Disease	renovascular hypertension (biomarker_via_orthology)	MPO SLC9A1	3.23e-03	19	132	2	DOID:1591 (biomarker_via_orthology)
Disease	leukemia (implicated_via_orthology)	ASH1L MEIS2	3.23e-03	19	132	2	DOID:1240 (implicated_via_orthology)
Disease	sclerosing cholangitis	HLA-DQB1 TNFAIP3 MAP3K7	3.26e-03	66	132	3	EFO_0004268
Disease	very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	USP24 CSNK2A1 SYNE2 PCSK7 KDF1	3.29e-03	222	132	5	EFO_0008317, EFO_0020943
Disease	Profound Mental Retardation	NF1 SHANK2 SETBP1 PRKCG	3.58e-03	139	132	4	C0020796
Disease	Mental Retardation, Psychosocial	NF1 SHANK2 SETBP1 PRKCG	3.58e-03	139	132	4	C0025363
Disease	Mental deficiency	NF1 SHANK2 SETBP1 PRKCG	3.58e-03	139	132	4	C0917816
Disease	myelodysplastic syndrome (is_marker_for)	DDX42 GATA2	3.58e-03	20	132	2	DOID:0050908 (is_marker_for)
Disease	Bladder Neoplasm	MPO MTOR MTHFR CHD6	3.67e-03	140	132	4	C0005695
Disease	Malignant neoplasm of urinary bladder	MPO MTOR MTHFR CHD6	3.76e-03	141	132	4	C0005684
Disease	chronic myeloid leukemia (is_implicated_in)	HLA-DQB1 MTHFR	3.94e-03	21	132	2	DOID:8552 (is_implicated_in)
Disease	cardiovascular system disease (is_implicated_in)	MPO MTHFR	3.94e-03	21	132	2	DOID:1287 (is_implicated_in)
Disease	severe acute respiratory syndrome, COVID-19	NCOA2 ARHGEF28 LRP1B AEBP2 ULBP2 RAET1L TBL1X	4.07e-03	447	132	7	EFO_0000694, MONDO_0100096
Disease	Hodgkin Disease	GATA3 TNFAIP3	4.33e-03	22	132	2	C0019829
Disease	age at voice drop	ECPAS IGSF1	4.33e-03	22	132	2	EFO_0007888
Disease	Conventional (Clear Cell) Renal Cell Carcinoma	LRP1B MTOR SYNE2 PAK1	4.47e-03	148	132	4	C0279702

Protein segments in the cluster

Peptide	Gene	Start	Entry
MAKAIMPVSLSEGRS	ZNF280A	96	P59817
SSASSTAERGMVKPM	AFDN	561	P55196
SMFSSRMTEDRAEPK	CATSPERG	1136	Q6ZRH7
GSSSASLLLDMGEMP	SLC4A9	76	Q96Q91
TMTDILSRGPKSMIS	AADAT	21	Q8N5Z0
SLEMSSDGEPLSRMD	AEBP2	206	Q6ZN18
ESEMSARIAKMSLSP	ANKLE2	791	Q86XL3
MDPRNTAMLGLGSDS	ASH1L	1	Q9NR48
EPRSFKMTSLDKMDG	CTAGE6	641	Q86UF2
EPRSFKMTSLDKMDG	CTAGE15	641	A4D2H0
RSAATGLPISMKIFM	CD40LG	11	P29965
SDLMNGTRPGMASTK	ADGRD1	841	Q6QNK2
NESSEVKSMMRSFPG	ADGRG4	166	Q8IZF6
PALFSMKMELAGSNT	BAZ2A	1166	Q9UIF9
GSKMPFGELMFESSS	ARPC1B	186	O15143
SVDSTGKTPLMMAAE	ANKRD28	851	O15084
GKITESSPFKSGMSM	ADAD1	491	Q96M93
STSSGLKQSMMPDEL	CASP8AP2	1551	Q9UKL3
SLKSSPSMSHMEALG	CAMSAP3	376	Q9P1Y5
SSGLDLPMKVVDMFG	ALG1L	66	Q6GMV1
KGSSEAPGKDSREMM	MROH7	706	Q68CQ1
TIMESMGSKLSPGAQ	PAAT	191	Q9H8K7
KMSDSLDTDPSMLGS	RAB3B	186	P20337
MSPSDFLDKLMGRTS	GLRA3	41	O75311
RGMFLISASSAGPEM	ARHGEF28	1151	Q8N1W1
GNRDMGRPMELTTKT	ANKRD13B	351	Q86YJ7
DIKSMSSPTIMAIGA	OXSM	111	Q9NWU1
SLMTGSRSTKATPEM	MUC16	16	Q8WXI7
PGSDKETSSMMIAST	MTHFR	101	P42898
MMAGRSPFDIVGSSD	PRKCI	446	P41743
PSDKMDALMPISGTS	LRP1B	1896	Q9NZR2
MEETTPTTLKGMFDS	SLC24A1	241	O60721
KLMETSMGFSSNAPT	MGA	836	Q8IWI9
VSPKEAGSMGSRMAE	GPR179	2206	Q6PRD1
MKASPEIISGRMTTA	MPC1L	46	P0DKB6
TKTPMDLTIRAGAMA	LRIG3	606	Q6UXM1
MPASMGSAVNDALKR	MEIS2	61	O14770
DRSMRKSFDMGGETL	KCNQ5	801	Q9NR82
KPSTGAMGDRLTAMK	DDX42	686	Q86XP3
AMDSARLSAAKSSPM	ECPAS	1326	Q5VYK3
GMMSLIGAPRSMDSD	PCSK7	551	Q16549
GPAMMLSDRLTFLGK	NUP85	526	Q9BW27
AGDTRSSEMPELTSM	MPO	401	P05164
PFMNSNLMGKTSERG	TCF12	101	Q99081
PTSEGKRMSADMSEI	MAP3K7	381	O43318
SLSGSLPGMSRGKSM	LRP6	1431	O75581
LPGMSRGKSMISSLS	LRP6	1436	O75581
MGAMSFGVSELLKAP	PRKCG	256	P05129
TKSGTASEMGTERAM	HEG1	226	Q9ULI3
LLMPSMSESDLTTSG	PTPN21	791	Q16825
PMRNTSTMIGAGSKD	PAK1	16	Q13153
ALRKMVSNMSGPSGE	CBY2	326	Q8NA61
SLTESMKMESGSPLR	GATA2	216	P23769
PDSMKLESSHSRGSM	GATA3	191	P23771
MLAMLSTPVAEGRDS	HLA-DQB1	21	P01920
MSLMESPEKDGSGTD	CDC45	381	O75419
TVVKDQARMGSSSMP	CSNK2A3	326	Q8NEV1
TMKPGSMSVEAFLAE	HCK	291	P08631
MTLDRPGEGATMLKT	IGSF1	1	Q8N6C5
LFPRKMTSHNGMEDS	CHD6	71	Q8TD26
PHTKMGGSRDSLLEM	DSCAML1	2016	Q8TD84
SPFTARVTGDDSMRM	FLNA	1946	P21333
MVISSDDPAMFGAKG	ADA2	436	Q9NZK5
TVVKDQARMGSSSMP	CSNK2A1	326	P68400
RFSPMTIDGMTSLAG	ELAVL2	251	Q12926
SDPKMTSNMLAFLGE	ERAP2	516	Q6P179
MAKMRFQLDASGEPT	DNAH9	1636	Q9NYC9
MDPVLSGRSATEMSG	FAM90A20P	161	A6NIJ5
GMERPSSLMDSSQEK	RPRD2	806	Q5VT52
TPIRDSMALSKMAGT	SDS	11	P20132
TLGFAMMASLDAPGK	SALL4	721	Q9UJQ4
LEMMAPSRGSAKSRG	CEP131	441	Q9UPN4
MAGIMAADRSESPSL	FANCD2	581	Q9BXW9
GSMPSEMESSRNDTK	MIA2	1261	Q96PC5
DGCSSSTMAPKMIFD	OR4C5	91	Q8NGB2
AMMERGPQTLKETSF	MTOR	2056	P42345
RASSSGEMSLPLMRA	RTL9	786	Q8NET4
PSLSRLMKSAIGEGM	ATP6V1B2	396	P21281
ERSSMLPTMAAGLNS	SNX29	156	Q8TEQ0
MLKSGMSPEQSRFQS	SRRM2	1126	Q9UQ35
ALRSMMEAGESASPA	PLCB4	476	Q15147
DKDMSSFMLPGSSHI	PRUNE2	1226	Q8WUY3
SKMETVLGQSMSSLP	SYNE2	3376	Q8WXH0
SMGLMEGRGTTTDRS	TMEM132D	846	Q14C87
SDMSLPDSMGAFNRR	TMEM255A	11	Q5JRV8
RMSSPALMAGASGKV	NXPE4	141	Q6UWF7
QAAFKLMSPTGGRMS	SEC24A	621	O95486
MSPSDFLDKLMGRTS	GLRA1	36	P23415
ESLPSSSKMHGMSFD	ERCC5	306	P28715
TIEGAAGPSFRLMKM	TELO2	106	Q9Y4R8
MMGSPKSLSETFLPN	STEAP2	6	Q8NFT2
SEGKSMFAGVPTMRE	SURF4	136	O15260
ESDLDLPEMGSGSMS	KDF1	221	Q8NAX2
LPEMGSGSMSSREID	KDF1	226	Q8NAX2
LDGMSPGESMSTDLV	ARHGAP44	761	Q17R89
SMAISPTPALKGMFD	SSTR2	281	P30874
ERPMSSASMASDFRK	SORBS2	241	O94875
GSTRLEPMFSMKTSS	SETDB1	391	Q15047
MLKFTRSLSMPDTSE	SHANK2	871	Q9UPX8
AEMEMKSSEPSGSLG	CCDC136	201	Q96JN2
SSSPGSRKMVVSAEM	AMMECR1	116	Q9Y4X0
MASLMITTKGSPRGE	CHRD	626	Q9H2X0
PDSGGVAKTMMESSL	CNOT1	241	A5YKK6
MSGMGENTSDPSRAE	NCOA2	1	Q15596
TSLDTSTMRAAMKPG	NCOA2	281	Q15596
MLPSSSSRMRSDGFD	NKAPD1	51	Q6ZUT1
DPSGMLLASCSDDMT	TBL1X	421	O60907
RSFVSKMSPLDMKDG	TRAPPC1	46	Q9Y5R8
ELDMTPFMASSKESR	USP22	431	Q9UPT9
KSLLFGAMSEMISPS	TICRR	1066	Q7Z2Z1
GAMSEMISPSEKGSA	TICRR	1071	Q7Z2Z1
KSGTGIAAMSVMRPE	ATP6V0C	36	P27449
MSPTKAAVDSLMTIG	ZBTB16	196	Q05516
MSSPSPGKRRMDTDV	UBE2H	1	P62256
LIKMASTDTPMARSG	TNFAIP3	171	P21580
MRGSTPLDVAASSVM	RYR3	2131	Q15413
GRSREDPAGMEASTM	SH2D3A	156	Q9BRG2
MSKGLPETRTDAAMS	SEPTIN3	1	Q9UH03
AKAAGLATMISTMRP	SF3B1	601	O75533
DFLMGMDSTLEPSAG	RAET1G	196	Q6H3X3
SERKGSMISVMSSEG	NF1	871	P21359
MSSEGNADTPVSKFM	NF1	881	P21359
GIMMRSKETSSPGTD	SLC9A1	761	P19634
DFLMGMDSTLEPSAG	RAET1L	196	Q5VY80
SGMRLSDMSPRSNTA	PLEKHH1	431	Q9ULM0
SLGRNMMESSELTPK	ZNF852	46	Q6ZMS4
GSESPMMIGELRSDL	USP24	2601	Q9UPU5
VSKSAPDSGLMGNSM	ZNF608	266	Q9ULD9
SSPEESIRMTKGITM	TLN2	2171	Q9Y4G6
SSLGSPMEMEDALSM	ZNF217	26	O75362
RQAMMKTDFPGDLGS	ZNF821	26	O75541
KRMLPSGMASSSQLI	TCHHL1	131	Q5QJ38
PSMMASASDDGTVRI	WDR26	626	Q9H7D7
PASRERSSSLQGMDM	WDR33	1211	Q9C0J8
ASGSPLDFMRSFMLK	TIGD5	441	Q53EQ6
DFLMGMDSTLEPSAG	ULBP2	196	Q9BZM5
MAMSELGTRKPSDGT	TBX19	1	O60806
RKERSSYDSSMSPGM	SETBP1	1321	Q9Y6X0
TIMESMGSKLSPGAQ	nan	26	Q499Y3
RMSLGGSDTMLKGAD	ZNF169	191	Q14929
LSAKDARGMTPFMSA	UBR5	1106	O95071
TLMMSGDKGISAFPE	UBE2C	41	O00762
ASQLGVRKMPGDMSS	nan	86	Q9UFV3
GMAMLRPDSFVGASS	WFIKKN2	536	Q8TEU8