Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	cyclin binding	GAK CDK12 CDK13	4.66e-05	35	40	3	GO:0030332
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat kinase activity	CDK12 CDK13	1.74e-04	10	40	2	GO:0008353
GeneOntologyMolecularFunction	channel regulator activity	CACNG3 CACNG4 AKAP9 TNNI3	3.98e-04	174	40	4	GO:0016247
GeneOntologyMolecularFunction	transporter regulator activity	CACNG3 CACNG4 AKAP9 TNNI3	4.25e-04	177	40	4	GO:0141108
GeneOntologyMolecularFunction	RNA polymerase II CTD heptapeptide repeat modifying activity	CDK12 CDK13	9.64e-04	23	40	2	GO:0140994
GeneOntologyMolecularFunction	protein kinase A regulatory subunit binding	AKAP9 SPATC1L	1.14e-03	25	40	2	GO:0034237
GeneOntologyMolecularFunction	cyclin-dependent protein kinase activity	CDK12 CDK13	1.64e-03	30	40	2	GO:0097472
GeneOntologyMolecularFunction	cyclin-dependent protein serine/threonine kinase activity	CDK12 CDK13	1.64e-03	30	40	2	GO:0004693
GeneOntologyBiologicalProcess	mRNA processing	TRA2A PPARGC1A ZC3H3 CDK12 CDK13 SRSF8 SRRM4 CLASRP	8.92e-06	551	40	8	GO:0006397
GeneOntologyBiologicalProcess	RNA splicing	TRA2A PPARGC1A CDK12 CDK13 SRSF8 SRRM4 CLASRP	4.51e-05	502	40	7	GO:0008380
GeneOntologyBiologicalProcess	mRNA metabolic process	TRA2A PPARGC1A ZC3H3 CDK12 CDK13 SRSF8 SRRM4 CLASRP BAG4	5.14e-05	917	40	9	GO:0016071
GeneOntologyBiologicalProcess	neurotransmitter receptor transport, postsynaptic endosome to lysosome	CACNG3 CACNG4	1.02e-04	8	40	2	GO:0098943
GeneOntologyBiologicalProcess	regulation of neurotransmitter receptor activity	CACNG3 CACNG4 DLGAP4	1.74e-04	56	40	3	GO:0099601
GeneOntologyBiologicalProcess	postsynaptic neurotransmitter receptor diffusion trapping	CACNG3 CACNG4	2.82e-04	13	40	2	GO:0098970
GeneOntologyBiologicalProcess	neurotransmitter receptor diffusion trapping	CACNG3 CACNG4	2.82e-04	13	40	2	GO:0099628
GeneOntologyBiologicalProcess	stem cell differentiation	SETD1A TBXT GAK CDK12 CDK13	2.99e-04	306	40	5	GO:0048863
GeneOntologyBiologicalProcess	receptor diffusion trapping	CACNG3 CACNG4	3.29e-04	14	40	2	GO:0098953
GeneOntologyCellularComponent	voltage-gated calcium channel complex	CACNG3 CACNG4 CATSPERG	9.31e-05	46	40	3	GO:0005891
GeneOntologyCellularComponent	cyclin/CDK positive transcription elongation factor complex	CDK12 CDK13	1.27e-04	9	40	2	GO:0008024
GeneOntologyCellularComponent	nuclear speck	SETD1A RBBP6 CDK12 CDK13 SRSF8 NXF1	1.57e-04	431	40	6	GO:0016607
GeneOntologyCellularComponent	calcium channel complex	CACNG3 CACNG4 CATSPERG	3.68e-04	73	40	3	GO:0034704
GeneOntologyCellularComponent	nuclear cyclin-dependent protein kinase holoenzyme complex	CDK12 CDK13	5.36e-04	18	40	2	GO:0019908
GeneOntologyCellularComponent	carboxy-terminal domain protein kinase complex	CDK12 CDK13	9.59e-04	24	40	2	GO:0032806
GeneOntologyCellularComponent	cation channel complex	CACNG3 CACNG4 AKAP9 CATSPERG	1.04e-03	235	40	4	GO:0034703
GeneOntologyCellularComponent	nuclear body	PPARGC1A SETD1A RBBP6 CDK12 CDK13 SRSF8 NXF1	1.47e-03	903	40	7	GO:0016604
GeneOntologyCellularComponent	AMPA glutamate receptor complex	CACNG3 CACNG4	1.50e-03	30	40	2	GO:0032281
GeneOntologyCellularComponent	postsynaptic density membrane	CACNG3 CACNG4 AKAP9	3.35e-03	157	40	3	GO:0098839
GeneOntologyCellularComponent	ionotropic glutamate receptor complex	CACNG3 CACNG4	3.36e-03	45	40	2	GO:0008328
GeneOntologyCellularComponent	neurotransmitter receptor complex	CACNG3 CACNG4	4.13e-03	50	40	2	GO:0098878
GeneOntologyCellularComponent	transcription elongation factor complex	CDK12 CDK13	5.15e-03	56	40	2	GO:0008023
GeneOntologyCellularComponent	dendrite	CACNG3 KIF21B PPARGC1A OPN4 AKAP9 DLGAP4	5.47e-03	858	40	6	GO:0030425
GeneOntologyCellularComponent	dendritic tree	CACNG3 KIF21B PPARGC1A OPN4 AKAP9 DLGAP4	5.53e-03	860	40	6	GO:0097447
GeneOntologyCellularComponent	monoatomic ion channel complex	CACNG3 CACNG4 AKAP9 CATSPERG	5.76e-03	378	40	4	GO:0034702
GeneOntologyCellularComponent	cyclin-dependent protein kinase holoenzyme complex	CDK12 CDK13	6.08e-03	61	40	2	GO:0000307
GeneOntologyCellularComponent	postsynaptic specialization membrane	CACNG3 CACNG4 AKAP9	6.66e-03	201	40	3	GO:0099634
Domain	RRM_dom	TRA2A PPARGC1A SETD1A SRSF8 NXF1	1.18e-04	227	40	5	IPR000504
Domain	VDCC_gsu	CACNG3 CACNG4	1.24e-04	8	40	2	IPR008368
Domain	RRM	TRA2A PPARGC1A SETD1A SRSF8 NXF1	1.26e-04	230	40	5	PS50102
Domain	-	TRA2A PPARGC1A SETD1A SRSF8 NXF1	1.65e-04	244	40	5	3.30.70.330
Domain	Nucleotide-bd_a/b_plait	TRA2A PPARGC1A SETD1A SRSF8 NXF1	2.14e-04	258	40	5	IPR012677
Domain	RRM_1	TRA2A PPARGC1A SETD1A SRSF8	9.98e-04	208	40	4	PF00076
Domain	RRM	TRA2A PPARGC1A SETD1A SRSF8	1.17e-03	217	40	4	SM00360
Domain	PMP22_Claudin	CACNG3 CACNG4	3.31e-03	40	40	2	PF00822
Domain	Kinesin_motor_CS	KIF21B STARD9	3.48e-03	41	40	2	IPR019821
Domain	KINESIN_MOTOR_1	KIF21B STARD9	4.00e-03	44	40	2	PS00411
Domain	-	KIF21B STARD9	4.00e-03	44	40	2	3.40.850.10
Domain	Kinesin_motor_dom	KIF21B STARD9	4.00e-03	44	40	2	IPR001752
Domain	Kinesin	KIF21B STARD9	4.00e-03	44	40	2	PF00225
Domain	KISc	KIF21B STARD9	4.00e-03	44	40	2	SM00129
Domain	KINESIN_MOTOR_2	KIF21B STARD9	4.00e-03	44	40	2	PS50067
Domain	PMP22/EMP/MP20/Claudin	CACNG3 CACNG4	4.18e-03	45	40	2	IPR004031
Domain	Znf_CCCH	ZC3H12C ZC3H3	6.85e-03	58	40	2	IPR000571
Domain	ZF_C3H1	ZC3H12C ZC3H3	6.85e-03	58	40	2	PS50103
Domain	Olfact_rcpt	OR2L2 OR2AK2 OR2L8 OR2L3	9.71e-03	393	40	4	IPR000725
Pathway	REACTOME_LGI_ADAM_INTERACTIONS	CACNG3 CACNG4	4.19e-04	14	31	2	MM15277
Pathway	REACTOME_LGI_ADAM_INTERACTIONS	CACNG3 CACNG4	4.19e-04	14	31	2	M27564
Pathway	REACTOME_PHASE_2_PLATEAU_PHASE	CACNG4 AKAP9	4.19e-04	14	31	2	MM15198
Pathway	REACTOME_PHASE_2_PLATEAU_PHASE	CACNG4 AKAP9	4.83e-04	15	31	2	M27456
Pathway	KEGG_CARDIAC_MUSCLE_CONTRACTION	CACNG3 CACNG4 TNNI3	6.80e-04	79	31	3	M17673
Pathway	KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM	CACNG3 CACNG4 TNNI3	7.85e-04	83	31	3	M8728
Pathway	KEGG_MEDICUS_REFERENCE_CARDIAC_TYPE_VGCC_RYR_SIGNALING	CACNG3 CACNG4	9.58e-04	21	31	2	M47950
Pathway	KEGG_MEDICUS_REFERENCE_SKELETAL_TYPE_VGCC_RYR_SIGNALING	CACNG3 CACNG4	9.58e-04	21	31	2	M47949
Pathway	KEGG_DILATED_CARDIOMYOPATHY	CACNG3 CACNG4 TNNI3	9.94e-04	90	31	3	M835
Pathway	KEGG_MEDICUS_REFERENCE_CA2_ENTRY_VOLTAGE_GATED_CA2_CHANNEL	CACNG3 CACNG4	1.36e-03	25	31	2	M47948
Pathway	REACTOME_CARDIAC_CONDUCTION	CACNG4 AKAP9 TNNI3	1.47e-03	103	31	3	MM15196
Pathway	REACTOME_TRAFFICKING_OF_AMPA_RECEPTORS	CACNG3 CACNG4	1.83e-03	29	31	2	MM15028
Pubmed	A systematic screen for CDK4/6 substrates links FOXM1 phosphorylation to senescence suppression in cancer cells.	TRA2A PPARGC1A RBL2 DEDD2 CLASRP	2.20e-08	73	40	5	22094256
Pubmed	The protein interaction landscape of the human CMGC kinase group.	TRA2A AKAP9 RBBP6 CDK12 CDK13 RBL2 SRSF8 CLASRP	1.07e-06	695	40	8	23602568
Pubmed	Interaction of CDK12 with NXF1 is a new node for the linking mechanism between transcription and transportation of mRNA.	CDK12 NXF1	1.29e-06	2	40	2	39270556
Pubmed	Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.	CDK12 CDK13	1.29e-06	2	40	2	24999027
Pubmed	CRTC2 enhances HBV transcription and replication by inducing PGC1α expression.	PPARGC1A CRTC2	1.29e-06	2	40	2	24529027
Pubmed	Dual Inhibition of CDK12/CDK13 Targets Both Tumor and Immune Cells in Ovarian Cancer.	CDK12 CDK13	1.29e-06	2	40	2	35857807
Pubmed	Human CDK12 and CDK13, multi-tasking CTD kinases for the new millenium.	CDK12 CDK13	1.29e-06	2	40	2	30319007
Pubmed	Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing.	CDK12 CDK13	1.29e-06	2	40	2	25561469
Pubmed	CDK12 is a transcription elongation-associated CTD kinase, the metazoan ortholog of yeast Ctk1.	CDK12 CDK13	1.29e-06	2	40	2	20952539
Pubmed	SR protein kinases promote splicing of nonconsensus introns.	TRA2A RBBP6 CDK12 CDK13 NXF1 CLASRP	3.42e-06	361	40	6	26167880
Pubmed	A targeted mutation in Cacng4 exacerbates spike-wave seizures in stargazer (Cacng2) mice.	CACNG3 CACNG4	3.87e-06	3	40	2	15677329
Pubmed	Human neuronal stargazin-like proteins, gamma2, gamma3 and gamma4; an investigation of their specific localization in human brain and their influence on CaV2.1 voltage-dependent calcium channels expressed in Xenopus oocytes.	CACNG3 CACNG4	3.87e-06	3	40	2	14505496
Pubmed	CDK12/13 promote splicing of proximal introns by enhancing the interaction between RNA polymerase II and the splicing factor SF3B1.	CDK12 CDK13	3.87e-06	3	40	2	37026485
Pubmed	The Cyclin K/Cdk12 complex maintains genomic stability via regulation of expression of DNA damage response genes.	CDK12 CDK13	7.73e-06	4	40	2	22012619
Pubmed	Endoplasmic reticulum stress downregulates PGC-1α in skeletal muscle through ATF4 and an mTOR-mediated reduction of CRTC2.	PPARGC1A CRTC2	7.73e-06	4	40	2	35428325
Pubmed	Identification of three novel Ca(2+) channel gamma subunit genes reveals molecular diversification by tandem and chromosome duplication.	CACNG3 CACNG4	7.73e-06	4	40	2	10613843
Pubmed	Transducer of regulated CREB-binding proteins (TORCs) induce PGC-1alpha transcription and mitochondrial biogenesis in muscle cells.	PPARGC1A CRTC2	7.73e-06	4	40	2	16980408
Pubmed	A family of gamma-like calcium channel subunits.	CACNG3 CACNG4	7.73e-06	4	40	2	10734232
Pubmed	Functional modulation of AMPA receptors by transmembrane AMPA receptor regulatory proteins.	CACNG3 CACNG4	7.73e-06	4	40	2	18304745
Pubmed	Critical role for TARPs in early development despite broad functional redundancy.	CACNG3 CACNG4	7.73e-06	4	40	2	18634809
Pubmed	SETD1A Methyltransferase Is Physically and Functionally Linked to the DNA Damage Repair Protein RAD18.	TRA2A SETD1A RBBP6 CDK12 SRSF8	1.01e-05	251	40	5	31076518
Pubmed	Cyclin K-containing kinase complexes maintain self-renewal in murine embryonic stem cells.	CDK12 CDK13	1.29e-05	5	40	2	22547058
Pubmed	Involvement of SIK2/TORC2 signaling cascade in the regulation of insulin-induced PGC-1alpha and UCP-1 gene expression in brown adipocytes.	PPARGC1A CRTC2	1.29e-05	5	40	2	19351809
Pubmed	Matrix-screening reveals a vast potential for direct protein-protein interactions among RNA binding proteins.	KIF21B RBBP6 CDK13 SRSF8 NXF1 SRRM4 BAG4	1.67e-05	723	40	7	34133714
Pubmed	Endoglin integrates BMP and Wnt signalling to induce haematopoiesis through JDP2.	TBXT TNNI3	2.70e-05	7	40	2	27713415
Pubmed	Calcium channel gamma subunits: a functionally diverse protein family.	CACNG3 CACNG4	3.60e-05	8	40	2	17652770
Pubmed	A cluster of three novel Ca2+ channel gamma subunit genes on chromosome 19q13.4: evolution and expression profile of the gamma subunit gene family.	CACNG3 CACNG4	4.62e-05	9	40	2	11170751
Pubmed	Identification of the human testis protein phosphatase 1 interactome.	TRA2A STARD9 SPATC1L	6.71e-05	68	40	3	21382349
Pubmed	The RNA-binding protein QKI governs a muscle-specific alternative splicing program that shapes the contractile function of cardiomyocytes.	AKAP9 TNNI3	7.05e-05	11	40	2	36627242
Pubmed	Accumulation of AMPA receptors in autophagosomes in neuronal axons lacking adaptor protein AP-4.	CACNG3 CACNG4	7.05e-05	11	40	2	18341993
Pubmed	Cyclin-dependent kinases: a family portrait.	CDK12 CDK13	8.45e-05	12	40	2	19884882
Pubmed	Pooled-matrix protein interaction screens using Barcode Fusion Genetics.	KPRP AKAP9 RBBP6 RBL2 BAG4	1.15e-04	419	40	5	27107012
Pubmed	RNA-binding proteins with basic-acidic dipeptide (BAD) domains self-assemble and aggregate in Alzheimer's disease.	TRA2A RBBP6 CDK12 SRSF8 NXF1 CLASRP	1.54e-04	713	40	6	29802200
Pubmed	Molecular characterization of mutant mouse strains generated from the EUCOMM/KOMP-CSD ES cell resource.	SRRM4 CRTC2	2.18e-04	19	40	2	23912999
Pubmed	QKI is a critical pre-mRNA alternative splicing regulator of cardiac myofibrillogenesis and contractile function.	AKAP9 TNNI3	2.42e-04	20	40	2	33397958
Pubmed	The mRNA-bound proteome and its global occupancy profile on protein-coding transcripts.	TRA2A RBBP6 CDK13 SRSF8 NXF1 BAG4	3.00e-04	807	40	6	22681889
Pubmed	High-resolution proteomics unravel architecture and molecular diversity of native AMPA receptor complexes.	CACNG3 CACNG4	3.50e-04	24	40	2	22632720
Pubmed	Automated yeast two-hybrid screening for nuclear receptor-interacting proteins.	PPARGC1A TNNI3 CLASRP	4.87e-04	133	40	3	15604093
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	TMEM209 TRA2A RBBP6 CDK13 SRSF8 NXF1 CLASRP	6.17e-04	1294	40	7	30804502
Pubmed	Different evolutionary processes shaped the mouse and human olfactory receptor gene families.	OR2L2 OR2AK2 OR2L8 OR2L3	6.21e-04	340	40	4	11875048
Pubmed	The olfactory receptor gene superfamily of the mouse.	OR2L2 OR2AK2 OR2L8 OR2L3	6.21e-04	340	40	4	11802173
Pubmed	A unified nomenclature for vertebrate olfactory receptors.	OR2L2 OR2AK2 OR2L8 OR2L3	6.42e-04	343	40	4	32295537
Pubmed	Odorant receptor expressed sequence tags demonstrate olfactory expression of over 400 genes, extensive alternate splicing and unequal expression levels.	OR2L2 OR2AK2 OR2L8 OR2L3	6.63e-04	346	40	4	14611657
Pubmed	All kinesin superfamily protein, KIF, genes in mouse and human.	KIF21B STARD9	8.37e-04	37	40	2	11416179
Pubmed	HDLBP Promotes Hepatocellular Carcinoma Proliferation and Sorafenib Resistance by Suppressing Trim71-dependent RAF1 Degradation.	TRA2A AKAP9 CDK12 CDK13 STARD9 SRSF8 NXF1	8.68e-04	1371	40	7	36244648
Pubmed	Cfp1 Controls Cardiomyocyte Maturation by Modifying Histone H3K4me3 of Structural, Metabolic, and Contractile Related Genes.	PPARGC1A TNNI3	8.83e-04	38	40	2	38196272
Pubmed	Charting the landscape of tandem BRCT domain-mediated protein interactions.	TRA2A CATSPERG CDK12 CDK13 CLASRP	9.85e-04	670	40	5	22990118
Pubmed	PTPN14 regulates Roquin2 stability by tyrosine dephosphorylation.	RBBP6 CDK12 CDK13 CRTC2 BAG4	1.04e-03	678	40	5	30209976
Interaction	SRSF4 interactions	TRA2A PPARGC1A RBBP6 CDK12 CDK13 SRSF8 NXF1 SRRM4	3.65e-08	300	35	8	int:SRSF4
Interaction	CLK1 interactions	TRA2A RBBP6 CDK12 SRSF8 SRRM4 CLASRP	1.92e-06	219	35	6	int:CLK1
Interaction	LUC7L interactions	TRA2A ZC3H3 RBBP6 SRSF8 SRRM4 CLASRP	3.42e-06	242	35	6	int:LUC7L
Interaction	CLK2 interactions	TRA2A RBBP6 SRSF8 NXF1 CLASRP	2.07e-05	195	35	5	int:CLK2
Interaction	SRSF6 interactions	TRA2A PPARGC1A RBBP6 CDK12 CDK13 SRSF8 CLASRP	2.12e-05	503	35	7	int:SRSF6
Interaction	CDK6 interactions	TRA2A PPARGC1A RBL2 DEDD2 CLASRP	3.30e-05	215	35	5	int:CDK6
Interaction	CLK3 interactions	TRA2A RBBP6 SRSF8 NXF1 CLASRP	3.68e-05	220	35	5	int:CLK3
Interaction	CLK4 interactions	RBBP6 SRRM4 CLASRP	6.05e-05	44	35	3	int:CLK4
Interaction	SNRPC interactions	TRA2A RBBP6 CDK12 SRSF8 NXF1 BAG4	9.93e-05	440	35	6	int:SNRPC
Interaction	FGFRL1 interactions	KPRP SETD1A NXF1	1.06e-04	53	35	3	int:FGFRL1
Interaction	DHX8 interactions	RBBP6 CDK12 CDK13 NXF1 CLASRP	1.40e-04	292	35	5	int:DHX8
Interaction	SRSF5 interactions	TRA2A PPARGC1A ZC3H3 CDK12 CDK13 SRSF8	1.49e-04	474	35	6	int:SRSF5
Interaction	NKAPD1 interactions	TRA2A ZC3H3 SRSF8 NXF1	1.69e-04	161	35	4	int:NKAPD1
Interaction	ROPN1L interactions	RSPH3 AKAP9	1.91e-04	12	35	2	int:ROPN1L
Interaction	SRPK2 interactions	TRA2A RBBP6 CDK12 CDK13 SRSF8 NXF1 CLASRP	1.97e-04	717	35	7	int:SRPK2
Interaction	SNRNP70 interactions	TRA2A RBBP6 CDK12 SRSF8 NXF1 SRRM4 CLASRP SPATC1L	2.27e-04	984	35	8	int:SNRNP70
Interaction	SRSF3 interactions	TRA2A RBBP6 CDK12 CDK13 SRSF8 NXF1	2.51e-04	522	35	6	int:SRSF3
Cytoband	1q44	OR2L2 OR2AK2 OR2L8 OR2L3	2.67e-06	110	40	4	1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr1q44	OR2L2 OR2AK2 OR2L8 OR2L3	4.87e-06	128	40	4	chr1q44
Cytoband	Ensembl 112 genes in cytogenetic band chr19q13	ZBTB32 IGFLR1 TNNI3 CATSPERG DEDD2 CLASRP	5.46e-04	1192	40	6	chr19q13
Cytoband	19q13.1	ZBTB32 CATSPERG	1.07e-03	55	40	2	19q13.1
Cytoband	1q21.3	KPRP CRTC2	4.71e-03	117	40	2	1q21.3
Cytoband	Ensembl 112 genes in cytogenetic band chr16p12	CACNG3 RBBP6	9.91e-03	172	40	2	chr16p12
GeneFamily	Olfactory receptors, family 2	OR2L2 OR2AK2 OR2L8 OR2L3	1.94e-05	113	26	4	149
GeneFamily	Calcium voltage-gated channel subunits	CACNG3 CACNG4	6.33e-04	26	26	2	253
GeneFamily	Cyclin dependent kinases	CDK12 CDK13	6.33e-04	26	26	2	496
GeneFamily	Zinc fingers CCCH-type	ZC3H12C ZC3H3	1.15e-03	35	26	2	73
GeneFamily	Kinesins\|Pleckstrin homology domain containing	KIF21B STARD9	1.98e-03	46	26	2	622
GeneFamily	RNA binding motif containing	TRA2A PPARGC1A SETD1A	3.43e-03	213	26	3	725
ToppCell	CV-Moderate-6\|CV / Virus stimulation, Condition and Cluster	TRA2A ZBTB32 IGFLR1 RBBP6	2.82e-05	196	40	4	7bced0cc2112697593c478fa291b8ed3941fb811
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW16-Neuronal\|GW16 / Sample Type, Dataset, Time_group, and Cell type.	SMPD3 AKAP9 SRRM4 DLGAP4	3.05e-05	200	40	4	84e4565d28a02700bf7f6730d1b3a58744ca0aea
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW26-Neuronal\|GW26 / Sample Type, Dataset, Time_group, and Cell type.	SMPD3 AKAP9 SRRM4 DLGAP4	3.05e-05	200	40	4	306926cb7a847871641f02e03d52dc56fd55711c
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-5w-Neuronal-Intermediate\|5w / Sample Type, Dataset, Time_group, and Cell type.	KIF21B SETD1A SMPD3 SRRM4	3.05e-05	200	40	4	c92e4fc0442404481fcac623d691dae6215b852d
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23-Neuronal-GABAergic_neurons\|GW23 / Sample Type, Dataset, Time_group, and Cell type.	CACNG4 AKAP9 SRRM4 DLGAP4	3.05e-05	200	40	4	c6bbd33bca86ac7a76a7ba704b3e141237d04549
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW10-Neuronal\|GW10 / Sample Type, Dataset, Time_group, and Cell type.	KIF21B AKAP9 SRRM4 DLGAP4	3.05e-05	200	40	4	04699d1149a143b96d6f292c0d70c4d3e6dfc611
Disease	IGF-like family receptor 1 measurement	ZBTB32 IGFLR1	2.16e-05	6	36	2	EFO_0801687
Disease	mean fractional anisotropy measurement	PPARGC1A ZBTB32 CAMTA1	2.14e-04	95	36	3	EFO_0008399
Disease	macular degeneration (is_implicated_in)	CACNG3 PPARGC1A	4.98e-04	27	36	2	DOID:4448 (is_implicated_in)
Disease	heart disease (implicated_via_orthology)	PPARGC1A TNNI3	9.90e-04	38	36	2	DOID:114 (implicated_via_orthology)
Disease	Arsenic Induced Polyneuropathy	TRA2A AKAP9	2.61e-03	62	36	2	C0751852
Disease	Arsenic Encephalopathy	TRA2A AKAP9	2.61e-03	62	36	2	C0751851
Disease	Arsenic Poisoning	TRA2A AKAP9	2.61e-03	62	36	2	C0311375
Disease	Arsenic Poisoning, Inorganic	TRA2A AKAP9	2.61e-03	62	36	2	C0274861
Disease	Nervous System, Organic Arsenic Poisoning	TRA2A AKAP9	2.61e-03	62	36	2	C0274862
Disease	Alzheimer disease, gastroesophageal reflux disease	CAMTA1 CDK13 CLASRP	2.69e-03	228	36	3	EFO_0003948, MONDO_0004975
Disease	Dermatologic disorders	TRA2A AKAP9	3.80e-03	75	36	2	C0037274
Disease	autosomal dominant compelling helio-ophthalmic outburst syndrome	CAMTA1 SRRM4	4.00e-03	77	36	2	EFO_0007887
Disease	dilated cardiomyopathy (implicated_via_orthology)	PPARGC1A TNNI3	4.31e-03	80	36	2	DOID:12930 (implicated_via_orthology)
Disease	thyroxine measurement	PPARGC1A STARD9	4.63e-03	83	36	2	EFO_0005130
Disease	thalamus volume	PPARGC1A CAMTA1	4.85e-03	85	36	2	EFO_0006935
Disease	Parkinson Disease	PPARGC1A GAK	4.85e-03	85	36	2	C0030567
Disease	physical activity	RBBP6 DLGAP4	5.19e-03	88	36	2	EFO_0003940
Disease	Myocardial Infarction	PPARGC1A TNNI3	6.02e-03	95	36	2	C0027051
Disease	type 2 diabetes mellitus (implicated_via_orthology)	PPARGC1A CRTC2	7.30e-03	105	36	2	DOID:9352 (implicated_via_orthology)

Protein segments in the cluster

Peptide	Gene	Start	Entry
TARSRAPYPSTYPVR	BAG4	106	O95429
RSLPSPQRYTRQERY	CATSPERG	646	Q6ZRH7
YRSRSDLDYIRSPLP	AKAP9	3831	Q99996
SVSPYSRRRSSSYER	CDK12	301	Q9NYV4
LRRPRSEPSNYYSSE	CAMTA1	1221	Q9Y6Y1
PYRYRFRRRSSSRST	CACNG3	226	O60359
RRRPVSPERYSYGTS	DEDD2	106	Q8WXF8
YSRRLPRSPSPYSRR	CDK13	351	Q14004
PYSRRRSPSYSRHSS	CDK13	361	Q14004
PYSSSSWRRSRSPYS	CDK13	386	Q14004
PLPSYFRSRSHSYLR	DLGAP4	501	Q9Y2H0
YTYVRPRSLRSPTED	OR2L2	256	Q8NH16
YTYLRPRSLRSPTED	OR2L3	256	Q8NG85
LYDRYSSPPASTTRR	RBL2	666	Q08999
LFTYTRPHSLRSPSR	OR2AK2	271	Q8NG84
RYNPYTTRPNRRGDT	NXF1	71	Q9UBU9
YTYLRPRSLRSPTED	OR2L8	256	Q8NGY9
PYYRDRVSRTVSLPT	KIF21B	1186	O75037
SPLQSARRPYIYSRL	SMPD3	86	Q9NY59
RSHSRSYSRSPPYPR	RBBP6	721	Q7Z6E9
SRSRSPPYRRYHSRS	RBBP6	756	Q7Z6E9
PPYRRYHSRSRSPQA	RBBP6	761	Q7Z6E9
SPLYVRSRSRSPYSR	PPARGC1A	616	Q9UBK2
RSRSRSPYSRRPRYD	PPARGC1A	621	Q9UBK2
RRHSRPYPSYRSTHR	OPN4	376	Q9UHM6
AVYNLSPRTYRPSRF	GAK	451	O14976
SSSPYARMPSYRYRR	CACNG4	226	Q9UBN1
SPLRRYTRHIDSSPY	CRTC2	116	Q53ET0
STFAYSLRPSRSPLR	IGFLR1	296	Q9H665
RPSYSSCFPQYRSRT	KPRP	211	Q5T749
APSRRQSYIPYRDSV	STARD9	326	Q9P2P6
SRSPYSRSPYSRSRY	SRSF8	156	Q9BRL6
SRSPYSRSRYSRSPY	SRSF8	161	Q9BRL6
YQRHTSYPPRRATRE	SETD1A	376	O15047
SSLPTGDRTRRSYYL	SPATC1L	166	Q9H0A9
YSRQSRSPSPRYSRE	CLASRP	641	Q8N2M8
RSPSPRYSREYSSSR	CLASRP	646	Q8N2M8
RRNIYRISIGSYPPS	FAP	421	Q12884
TSRAPSTYTYTSRPR	RSPH3	151	Q86UC2
SARYPRPSRRGYSSH	ZC3H3	51	Q8IXZ2
PSPYYSRYRSRSRSR	TRA2A	261	Q13595
SRRSPSYSRYSPSRE	SRRM4	451	A7MD48
CDRYPTLRSHRSSPY	TBXT	276	O15178
PAPIRRRSSNYRAYA	TNNI3	16	P19429
RSRYRSSPTVYNSPT	TMEM209	216	Q96SK2
IRSTFLYSSSRPSRP	ZBTB32	461	Q9Y2Y4
LYDSSPSRQRKPYSR	ZC3H12C	756	Q9C0D7