Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
Domain	Somatstn_rcpt	SSTR3 SSTR5	1.75e-04	5	79	2	IPR000586
Domain	HTH_motif	HOXD9 HOXD12 DLX2	3.12e-03	69	79	3	IPR000047
Domain	Pentatricopeptide_repeat	IFT140 HTT	4.22e-03	23	79	2	IPR002885
Domain	PAS_fold_3	PER2 SIM2	4.22e-03	23	79	2	IPR013655
Domain	PAS_3	PER2 SIM2	4.22e-03	23	79	2	PF08447
Domain	PDEase_catalytic_dom	TBC1D10B SAMHD1	4.22e-03	23	79	2	IPR002073
Domain	PAS-assoc_C	PER2 SIM2	4.59e-03	24	79	2	IPR000700
Domain	GroES-like	FASN ABCA7	4.59e-03	24	79	2	IPR011032
Domain	PAC	PER2 SIM2	5.38e-03	26	79	2	IPR001610
Domain	PAC	PER2 SIM2	5.38e-03	26	79	2	SM00086
Domain	PAC	PER2 SIM2	5.38e-03	26	79	2	PS50113
Domain	SAM	CASKIN2 SAMHD1 EPHA10	6.18e-03	88	79	3	SM00454
Domain	PID	NUMBL SHC3	6.22e-03	28	79	2	PF00640
Domain	Homeobox_metazoa	HOXD9 HOXD12 DLX2	6.57e-03	90	79	3	IPR020479
Domain	SAM_DOMAIN	CASKIN2 SAMHD1 EPHA10	7.63e-03	95	79	3	PS50105
Domain	Homeobox_CS	OTX1 HOXD9 HOXD12 DLX2	8.01e-03	186	79	4	IPR017970
Domain	PID	NUMBL SHC3	8.07e-03	32	79	2	PS01179
Domain	PAS	PER2 SIM2	8.07e-03	32	79	2	SM00091
Domain	SAM	CASKIN2 SAMHD1 EPHA10	8.08e-03	97	79	3	IPR001660
Pubmed	Genetic and physical mapping of the mouse Ulnaless locus.	HOXD9 HOXD12 DLX2	2.84e-06	12	83	3	8978061
Pubmed	Disruption of peripheral circadian timekeeping in a mouse model of Huntington's disease and its restoration by temporally scheduled feeding.	PER2 HTT	5.63e-06	2	83	2	20668203
Pubmed	Activation of anaplastic lymphoma kinase is responsible for hyperphosphorylation of ShcC in neuroblastoma cell lines.	ALK SHC3	5.63e-06	2	83	2	12185581
Pubmed	Somatostatin receptor subtype expression in human thyroid and thyroid carcinoma cell lines.	SSTR3 SSTR5	5.63e-06	2	83	2	9177396
Pubmed	Emphasis of FAS/FASL gene polymorphism in patients with non-muscle invasive bladder cancer.	FASN FASLG	5.63e-06	2	83	2	29453645
Pubmed	Assignment of cytoplasmic alpha-mannosidase (MANA) and confirmation of mitochondrial isocitrate dehydrogenase (IDHM) to the q11 leads to qter region of chromosome 15 in man.	MAN2C1 IDH2	5.63e-06	2	83	2	752528
Pubmed	KSRP is critical in governing hepatic lipid metabolism through controlling Per2 expression.	PER2 KHSRP	5.63e-06	2	83	2	25514904
Pubmed	SRCAP complex promotes lung cancer progression by reprograming the oncogenic transcription of Hippo-YAP/TAZ signaling pathway.	FASN RBBP6 RANBP3 DIDO1 TEAD1 PALLD RSBN1L HTT KHSRP	6.65e-06	549	83	9	38280479
Pubmed	Gene expression of somatostatin receptor subtypes SSTR2a, SSTR3 and SSTR5 in peripheral blood of neuroendocrine lung cancer affected patients.	SSTR3 SSTR5	1.69e-05	3	83	2	21503779
Pubmed	Mammalian orthologues of a yeast regulator of nonsense transcript stability.	ACD NCAN	1.69e-05	3	83	2	8855285
Pubmed	Dishevelled-KSRP complex regulates Wnt signaling through post-transcriptional stabilization of beta-catenin mRNA.	DVL3 KHSRP	1.69e-05	3	83	2	20332102
Pubmed	Proto-oncogene FBI-1 (Pokemon) and SREBP-1 synergistically activate transcription of fatty-acid synthase gene (FASN).	ZBTB7A FASN	1.69e-05	3	83	2	18682402
Pubmed	Increased apoptosis and early embryonic lethality in mice nullizygous for the Huntington's disease gene homologue.	OTX1 HTT	1.69e-05	3	83	2	7550343
Pubmed	The expression of somatostatin receptors 3, 4 and 5 in laryngeal pathology.	SSTR3 SSTR5	1.69e-05	3	83	2	18066572
Pubmed	Cell contact and Nf2/Merlin-dependent regulation of TEAD palmitoylation and activity.	FASN TEAD1	1.69e-05	3	83	2	31043565
Pubmed	Contribution of DNA methylation to the expression of FCGRT in human liver and myocardium.	ZBTB7A FCGRT	1.69e-05	3	83	2	31209240
Pubmed	Selective regulation of somatostatin receptor subtype signaling: evidence for constitutive receptor activation.	SSTR3 SSTR5	1.69e-05	3	83	2	17609435
Pubmed	The role of CA-125, GLS and FASN in predicting cytoreduction for epithelial ovarian cancers.	FASN MUC16	1.69e-05	3	83	2	32698888
Pubmed	Expression of somatostatin receptors 3, 4, and 5 in mouse kidney proximal tubules.	SSTR3 SSTR5	1.69e-05	3	83	2	12472768
Pubmed	Somatostatin receptors 3, 4 and 5 play important roles in gallbladder cancer.	SSTR3 SSTR5	1.69e-05	3	83	2	23991955
Pubmed	Murine genes related to the Drosophila AbdB homeotic genes are sequentially expressed during development of the posterior part of the body.	HOXD9 HOXD12	3.37e-05	4	83	2	1676674
Pubmed	Somatostatin and dopamine receptor expression in neuroendocrine neoplasms: correlation of immunohistochemical findings with somatostatin receptor scintigraphy visual scores.	SSTR3 SSTR5	3.37e-05	4	83	2	25808161
Pubmed	Hereditary Dystonia Overview	PANK2 POLG SAMHD1 HTT	4.58e-05	82	83	4	20301334
Pubmed	Impact of cytosine methylation on DNA binding specificities of human transcription factors.	ZBTB7A OTX1 HOXD9 KLF13 HOXD12 SOX30 DLX2 TEAD1	4.80e-05	544	83	8	28473536
Pubmed	Somatostatin sst2 receptor knock-out mice: localisation of sst1-5 receptor mRNA and binding in mouse brain by semi-quantitative RT-PCR, in situ hybridisation histochemistry and receptor autoradiography.	SSTR3 SSTR5	5.60e-05	5	83	2	11897118
Pubmed	[Somatostatin receptor genes expression and effects of octreotide on orbital fibroblasts from Graves' ophthalmopathy].	SSTR3 SSTR5	5.60e-05	5	83	2	11753241
Pubmed	Polymorphisms of coding trinucleotide repeats of homeogenes in neurodevelopmental psychiatric disorders.	OTX1 DLX2	5.60e-05	5	83	2	19018235
Pubmed	The Hox-4.8 gene is localized at the 5' extremity of the Hox-4 complex and is expressed in the most posterior parts of the body during development.	HOXD9 HOXD12	5.60e-05	5	83	2	1685889
Pubmed	A function for all posterior Hoxd genes during digit development?	HOXD9 HOXD12	5.60e-05	5	83	2	22374744
Pubmed	Acromegaly: correlation between expression of somatostatin receptor subtypes and response to octreotide-lar treatment.	SSTR3 SSTR5	5.60e-05	5	83	2	19330452
Pubmed	Somatostatin receptor genes are expressed in lymphocytes from retroorbital tissues in Graves' disease.	SSTR3 SSTR5	5.60e-05	5	83	2	12414882
Pubmed	Prognostic Value of Somatostatin Receptor Subtypes in Pancreatic Neuroendocrine Tumors.	SSTR3 SSTR5	5.60e-05	5	83	2	26474434
Pubmed	Somatostatin receptor subtypes in human type 2 diabetic islets.	SSTR3 SSTR5	5.60e-05	5	83	2	20182388
Pubmed	Profiling of somatostatin receptor subtype expression by quantitative PCR and correlation with clinicopathological features in pancreatic endocrine tumors.	SSTR3 SSTR5	5.60e-05	5	83	2	20717067
Pubmed	Expression of somatostatin receptor types 1-5 in 81 cases of gastrointestinal and pancreatic endocrine tumors. A correlative immunohistochemical and reverse-transcriptase polymerase chain reaction analysis.	SSTR3 SSTR5	5.60e-05	5	83	2	12021920
Pubmed	Immunohistochemical detection and localization of somatostatin receptor subtypes in prostate tissue from patients with bladder outlet obstruction.	SSTR3 SSTR5	5.60e-05	5	83	2	18936524
Pubmed	Expression of murine HOXD9 during embryonic joint patterning and in human T lymphotropic virus type I tax transgenic mice with arthropathy resembling rheumatoid arthritis.	HOXD9 HOXD12	5.60e-05	5	83	2	10211882
Pubmed	Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental disease.	IFT140 FRAS1	5.60e-05	5	83	2	23469164
Pubmed	Human somatostatin receptor genes: localization to human chromosomes 14, 17, and 22 and identification of simple tandem repeat polymorphisms.	SSTR3 SSTR5	5.60e-05	5	83	2	8449518
Pubmed	The function of Hox genes in the morphogenesis of the vertebrate limb.	HOXD9 HOXD12	5.60e-05	5	83	2	8099264
Pubmed	An immunohistochemical investigation of the expression of somatostatin receptor subtypes - should therapeutic trials be performed to determine the efficacy of somatostatin analogs in treating advanced thyroid malignances?	SSTR3 SSTR5	5.60e-05	5	83	2	25962406
Pubmed	A census of human transcription factors: function, expression and evolution.	ZBTB7A OTX1 HOXD9 KLF13 HOXD12 SOX30 AKNA DLX2 MESP1 TEAD1	6.09e-05	908	83	10	19274049
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	ATMIN FRAS1 FASN PER2 KIF26A POLG SORBS3 AKNA DLX2 ABCA7 HTT	6.32e-05	1105	83	11	35748872
Pubmed	Expression of Ki-67, PTTG1, FGFR4, and SSTR 2, 3, and 5 in nonfunctioning pituitary adenomas: a high throughput TMA, immunohistochemical study.	SSTR3 SSTR5	8.39e-05	6	83	2	22419713
Pubmed	Cloning, mRNA expression, and chromosomal mapping of mouse and human preprocortistatin.	SSTR3 SSTR5	8.39e-05	6	83	2	9205124
Pubmed	Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis.	FASN POLG	8.39e-05	6	83	2	31358769
Pubmed	Genetic analysis of a conserved sequence in the HoxD complex: regulatory redundancy or limitations of the transgenic approach?	HOXD9 HOXD12	8.39e-05	6	83	2	9733096
Pubmed	Cloning and functional characterization of a family of human and mouse somatostatin receptors expressed in brain, gastrointestinal tract, and kidney.	SSTR3 SSTR5	8.39e-05	6	83	2	1346068
Pubmed	Impaired TrkB-mediated ERK1/2 activation in huntington disease knock-in striatal cells involves reduced p52/p46 Shc expression.	SHC3 HTT	8.39e-05	6	83	2	20442398
Pubmed	Differential expression of two different homeobox gene families during mouse tegument morphogenesis.	OTX1 HOXD9	8.39e-05	6	83	2	7779685
Pubmed	Brain somatostatin receptors are up-regulated in somatostatin-deficient mice.	SSTR3 SSTR5	8.39e-05	6	83	2	12145348
Pubmed	Mutations in HOXD13 underlie syndactyly type V and a novel brachydactyly-syndactyly syndrome.	HOXD9 HOXD12	8.39e-05	6	83	2	17236141
Pubmed	The constrained architecture of mammalian Hox gene clusters.	HOXD9 HOXD12	8.39e-05	6	83	2	31209053
Pubmed	Identification and characterization of a novel human cortistatin-like peptide.	SSTR3 SSTR5	8.39e-05	6	83	2	9125122
Pubmed	Coordinate expression of the murine Hox-5 complex homoeobox-containing genes during limb pattern formation.	HOXD9 HOXD12	8.39e-05	6	83	2	2574828
Pubmed	Neural stem cell lineages are regionally specified, but not committed, within distinct compartments of the developing brain.	OTX1 DLX2	8.39e-05	6	83	2	11782416
Pubmed	β1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance.	NUMBL MESP1	8.39e-05	6	83	2	29653101
Pubmed	Genetic variation in the SST gene and its receptors in relation to circulating levels of insulin-like growth factor-I, IGFBP3, and prostate cancer risk.	SSTR3 SSTR5	8.39e-05	6	83	2	19423539
Pubmed	Context-dependent enhancer function revealed by targeted inter-TAD relocation.	HOXD9 HOXD12	8.39e-05	6	83	2	35715427
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	PRUNE2 PER2 DIDO1 NACAD	1.16e-04	104	83	4	9205841
Pubmed	Expression and localization of somatostatin receptor types 3, 4 and 5 in the wild-type, SSTR1 and SSTR1/SSTR2 knockout mouse cochlea.	SSTR3 SSTR5	1.17e-04	7	83	2	25149275
Pubmed	Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors.	NUMBL MESP1	1.17e-04	7	83	2	24843018
Pubmed	An update of mouse and human HOX gene nomenclature.	HOXD9 HOXD12	1.17e-04	7	83	2	1973145
Pubmed	Patterns of gene expression in the neural plate and neural tube subdivide the embryonic forebrain into transverse and longitudinal domains.	OTX1 DLX2	1.17e-04	7	83	2	9078438
Pubmed	Null mutant mouse models of somatostatin and cortistatin, and their receptors.	SSTR3 SSTR5	1.17e-04	7	83	2	18206294
Pubmed	Immunohistochemical distribution of somatostatin and somatostatin receptor subtypes (SSTR1-5) in hypothalamus of ApoD knockout mice brain.	SSTR3 SSTR5	1.17e-04	7	83	2	22581439
Pubmed	Mesomelic dysplasias associated with the HOXD locus are caused by regulatory reallocations.	HOXD9 HOXD12	1.17e-04	7	83	2	34408147
Pubmed	Uncoupling time and space in the collinear regulation of Hox genes.	HOXD9 HOXD12	1.17e-04	7	83	2	19266017
Pubmed	Monodactylous limbs and abnormal genitalia are associated with hemizygosity for the human 2q31 region that includes the HOXD cluster.	HOXD9 HOXD12	1.56e-04	8	83	2	10364522
Pubmed	Control of Hoxd genes' collinearity during early limb development.	HOXD9 HOXD12	1.56e-04	8	83	2	16399081
Pubmed	Modeling Hox gene regulation in digits: reverse collinearity and the molecular origin of thumbness.	HOXD9 HOXD12	1.56e-04	8	83	2	18245448
Pubmed	A 117-kb microdeletion removing HOXD9-HOXD13 and EVX2 causes synpolydactyly.	HOXD9 HOXD12	1.56e-04	8	83	2	11778160
Pubmed	Identification of APBB1 as a substrate for anaplastic lymphoma kinase.	DVL3 ALK PALLD	1.62e-04	44	83	3	39115278
Pubmed	The conserved Bardet-Biedl syndrome proteins assemble a coat that traffics membrane proteins to cilia.	SSTR3 SSTR5	2.00e-04	9	83	2	20603001
Pubmed	Bimodal control of Hoxd gene transcription in the spinal cord defines two regulatory subclusters.	HOXD9 HOXD12	2.00e-04	9	83	2	22278926
Pubmed	Formin isoforms are differentially expressed in the mouse embryo and are required for normal expression of fgf-4 and shh in the limb bud.	HOXD9 HOXD12	2.00e-04	9	83	2	7588050
Pubmed	Binding specificity and in vivo targets of the EH domain, a novel protein-protein interaction module.	NUMBL EPN2	2.00e-04	9	83	2	9303539
Pubmed	Large scale transgenic and cluster deletion analysis of the HoxD complex separate an ancestral regulatory module from evolutionary innovations.	HOXD9 HOXD12	2.50e-04	10	83	2	11544178
Pubmed	Clustering of two fragile sites and seven homeobox genes in human chromosome region 2q31-->q32.1.	HOXD9 HOXD12	2.50e-04	10	83	2	11060466
Pubmed	Genetic variation in the growth hormone synthesis pathway in relation to circulating insulin-like growth factor-I, insulin-like growth factor binding protein-3, and breast cancer risk: results from the European prospective investigation into cancer and nutrition study.	SSTR3 SSTR5	2.50e-04	10	83	2	16214911
Pubmed	Demonstration of inflammation-induced cancer and cancer immunoediting during primary tumorigenesis.	FASLG IFNAR2	2.50e-04	10	83	2	18178624
Pubmed	Structural and functional differences in the long non-coding RNA hotair in mouse and human.	HOXD9 HOXD12	2.50e-04	10	83	2	21637793
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	RALGAPA1 IFT140 KIF26A CASKIN2 AKNA DIDO1 NACAD	2.77e-04	529	83	7	14621295
Pubmed	Mammalian APE1 controls miRNA processing and its interactome is linked to cancer RNA metabolism.	RALGAPA1 TBC1D10B MVB12A CASKIN2 POLG SORBS3 DIDO1 VARS2 IFNAR2	3.63e-04	925	83	9	28986522
Pubmed	Control of Hoxd gene transcription in the mammary bud by hijacking a preexisting regulatory landscape.	HOXD9 HOXD12	3.66e-04	12	83	2	27856734
Pubmed	Screening large numbers of expression patterns of transcription factors in late stages of the mouse thymus.	ZBTB7A OTX1 PER2 HOXD12 FBLIM1	4.27e-04	263	83	5	20932939
Pubmed	Disruption of PAX6 function in mice homozygous for the Pax6Sey-1Neu mutation produces abnormalities in the early development and regionalization of the diencephalon.	DLX2 SIM2	4.31e-04	13	83	2	9232602
Pubmed	Expression patterns of two murine homologs of Drosophila single-minded suggest possible roles in embryonic patterning and in the pathogenesis of Down syndrome.	DLX2 SIM2	4.31e-04	13	83	2	8812055
Pubmed	Hox gene function in vertebrate gut morphogenesis: the case of the caecum.	HOXD9 HOXD12	4.31e-04	13	83	2	17942481
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ATMIN MAGI2 FRAS1 PER2 MEGF9 SPHKAP	4.37e-04	407	83	6	12693553
Pubmed	Cleft palate defect of Dlx1/2-/- mutant mice is caused by lack of vertical outgrowth in the posterior palate.	DLX2 SIM2	5.03e-04	14	83	2	22972697
Pubmed	The mouse Ulnaless mutation deregulates posterior HoxD gene expression and alters appendicular patterning.	HOXD9 HOXD12	5.03e-04	14	83	2	9342041
Pubmed	Gli3 (Xt) and formin (ld) participate in the positioning of the polarising region and control of posterior limb-bud identity.	HOXD9 HOXD12	5.03e-04	14	83	2	9834182
Pubmed	Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis.	OTX1 NUMBL	5.03e-04	14	83	2	14687546
Pubmed	A gene expression map of human chromosome 21 orthologues in the mouse.	COL18A1 FTCD SIM2 IFNAR2	5.70e-04	158	83	4	12466855
Pubmed	Altered transmission of HOX and apoptotic SNPs identify a potential common pathway for clubfoot.	HOXD9 HOXD12	5.79e-04	15	83	2	19938081
Pubmed	Characterization of the murine mafF gene.	FASN SSTR3	5.79e-04	15	83	2	10409670
Pubmed	Hoxd and Gli3 interactions modulate digit number in the amniote limb.	HOXD9 HOXD12	5.79e-04	15	83	2	17714700
Pubmed	Mapping the Ku Interactome Using Proximity-Dependent Biotin Identification in Human Cells.	RBBP6 RANBP3 DIDO1 RSBN1L KHSRP	5.96e-04	283	83	5	30585729
Pubmed	Human chromosome 21 gene expression atlas in the mouse.	COL18A1 FTCD SIM2 IFNAR2	6.41e-04	163	83	4	12466854
GeneFamily	Somatostatin receptors	SSTR3 SSTR5	9.37e-05	5	56	2	257
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_7DY_DN	KRBA1 MAN2C1 CSF3R RANBP3 POLG SORBS3 DVL3 WHAMM DIDO1 RIOK3 ARHGAP27	5.07e-06	634	83	11	M40866
Coexpression	HE_LIM_SUN_FETAL_LUNG_C1_SMG_CELL	PER2 MICALL2 NUMBL SLC22A23 MUC16 SAMHD1 MESP1 ARHGAP27 NACAD PALLD IFNAR2	3.27e-05	775	83	11	M45713
Coexpression	GSE22432_MULTIPOTENT_PROGENITOR_VS_CDC_UP	PANK2 PER2 HOXD9 SAMHD1 SSTR3 NACAD	4.12e-05	199	83	6	M7817
Coexpression	GSE45365_NK_CELL_VS_CD11B_DC_UP	HOXD12 NCAN RBP3 MUC16 ALK EPN2	4.12e-05	199	83	6	M10030
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 GPR150 DTX1 TEAD1 NACAD	1.42e-06	188	83	6	dc52dd2957be3f40001f0a56f3d9ac9d66ea466e
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 GPR150 DTX1 TEAD1 NACAD	1.42e-06	188	83	6	2ef08313087e91985bcffc46c3798470cdeec49c
ToppCell	droplet-Lung-1m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|1m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 GPR150 DTX1 TEAD1 NACAD	1.42e-06	188	83	6	1f1604b6dc0a8ad0be3d9aac0bef448459c22465
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1 SHC3	1.40e-05	164	83	5	4cfc9f92e49f86d3639e018b35b6a60dc62f494a
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1 SHC3	1.40e-05	164	83	5	7a8e5ef52a8fd2877d59ef0696af8a7af90bbed6
ToppCell	PND10-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1 SHC3	1.40e-05	164	83	5	5e5bd81414ea2d64f73cdef19a0a78c17bec8c18
ToppCell	PND10-Endothelial-Endothelial_lymphatic\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1 SHC3	1.40e-05	164	83	5	f13b8d9b7f42193f333d9a77571a1dde6bbb48d8
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXD9 DTX1 LRTM1 TEAD1 SHC3	1.91e-05	175	83	5	9d082ba0e350162aa6e71b668be074b12a27c7ab
ToppCell	facs-Lung-ENDOMUCIN-18m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HOXD9 DTX1 LRTM1 TEAD1 SHC3	1.91e-05	175	83	5	f641f34b52aec5d047430a6f9d026e915da6c11d
ToppCell	TCGA-Adrenal-Primary_Tumor-Pheochromocytoma-Pheochromocytoma-1\|TCGA-Adrenal / Sample_Type by Project: Shred V9	PRUNE2 KIF26A DLX2 TEAD1 ALK	2.13e-05	179	83	5	431e1b29015ec817f778499106d24b19cfc825ae
ToppCell	Smart-seq2-blood_(Smart-seq2)-myeloid-myeloid_monocytic-classical_monocyte\|blood_(Smart-seq2) / Per Platform+tissue_group, by lineage_subgroup, cell_group, cell_type	ZBTB7A CSF3R MEGF9 MUC16 CSMD1	2.56e-05	186	83	5	23b8d51d20b05795a73892d3e20e0f9b6a207820
ToppCell	droplet-Lung-LUNG-1m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 HOXD9 GPR150 DTX1 TEAD1	2.62e-05	187	83	5	9c9ae8725905ba0cfe407878006ed06c2480fb72
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI2 FRAS1 MEGF9 SIM2	2.62e-05	187	83	5	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	droplet-Lung-LUNG-1m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 HOXD9 GPR150 DTX1 TEAD1	2.62e-05	187	83	5	9e9460e57cdc9cd0a0de2866b140e06d0bc19a8f
ToppCell	facs-Lung-nan-3m-Endothelial-Lymphatic_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 HOXD9 FCGRT DTX1 SHC3	2.90e-05	191	83	5	48823a97c38263f2c6e58348214f5b62773a6368
ToppCell	facs-Lung-nan-3m-Endothelial-endothelial_cell_of_lymphatic_vessel\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 HOXD9 FCGRT DTX1 SHC3	2.90e-05	191	83	5	0eedc66e967b1837ce2c14f8c14b3c1eba868c76
ToppCell	CV-Moderate-6\|Moderate / Virus stimulation, Condition and Cluster	CCDC91 ZBTB7A KLF13 RBBP6 SAMHD1	3.21e-05	195	83	5	2b8a72d7e755b9655c7a496000d10ff06e50862b
ToppCell	PBMC-Control-cDC_3\|Control / Compartment, Disease Groups and Clusters	ZNF469 AKNA DIDO1 SAMHD1 ARHGAP27	3.29e-05	196	83	5	09d197b321ff9f13c0672ea059c850845b0dbbd5
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NUMBL SLC22A23 NCAN DISP3 KLHL35	3.45e-05	198	83	5	6d12ecaa9532c134d9c4562534dcb59a6420b4d3
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-IPC_like-IPs_and_early_cortical_neurons\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	NUMBL SLC22A23 NCAN DISP3 KLHL35	3.45e-05	198	83	5	7943e4f67c3d6efb5c8b00aa0ff3cfe7be10c48d
ToppCell	Healthy_donor-Classical_Monocyte\|World / disease group, cell group and cell class (v2)	CSF3R MEGF9 FCGRT SAMHD1 ZNF467	3.53e-05	199	83	5	45e9099a13becb1e235435ceaaffb92b82ce34ee
ToppCell	10x3'2.3-week_14-16-Myeloid_monocytic-monocyte-CD14_monocyte\|week_14-16 / cell types per 3 fetal stages;per 3',per 5'	CSF3R MEGF9 FCGRT SAMHD1 ZNF467	3.62e-05	200	83	5	527b7388700096686293f3f6b112269e87908dfa
ToppCell	Posterior_cortex-Endothelial-MURAL-M1(Rgs5Acta2)-M1_1\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	COL18A1 MESP1 FBLIM1 PALLD	7.52e-05	120	83	4	a320799ab5f2ce872e038b15841a23174c5436e8
ToppCell	Endothelial-G\|World / shred on cell class and cell subclass (v4)	COL18A1 HOXD9 FCGRT DTX1	8.53e-05	124	83	4	4b72809463f2986b7d1b7ab9de633ac4d7854a92
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	NCAN LRTM1 DIDO1 FHIP2B	1.25e-04	137	83	4	ed81624b9167255ce88dcf6ad7f1636376ea0525
ToppCell	PND07-28-samps-Mesenchymal-Mesenchymal_stem_cell-Mesenchymal_fibroblast\|PND07-28-samps / Age Group, Lineage, Cell class and subclass	NCAN LRTM1 DIDO1 FHIP2B	1.25e-04	137	83	4	47859aa25f32367461c1ec75ed9060bee430c6b7
ToppCell	PBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c10-MKI67-GZMK\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	CASKIN2 CCDC15 MESP1 TEAD1	1.56e-04	145	83	4	34fc6da04d4fe0817e37cdcd844fe2a6e53a4796
ToppCell	367C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_4\|Lymphocytic / Donor, Lineage, Cell class and subclass (all cells)	NGEF MUC16 FTCD PALLD	1.69e-04	148	83	4	c240d506151fa90c59f40008c5fb31984c6f6f8f
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Goblet_cell,_top_of_crypt_(Distal)\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPHKAP LRTM1 DISP3 SIM2	1.69e-04	148	83	4	dfd3f2c4b884ea9e23831a242a89ac985b409640
ToppCell	Frontal_cortex-Neuronal-Excitatory-eN2(Slc17a7_Slc17a6)-Syt6\|Frontal_cortex / BrainAtlas - Mouse McCarroll V32	OTX1 GPR150 NGEF SSTR3	1.78e-04	150	83	4	9d5bbdca19da60e1a2121ef64ec8e1375a5dbf6d
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Sst_(Striatum,_interneuron)-\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MESP1 FTCD FASLG	1.83e-04	59	83	3	0946b53be12a9926d876c75ddf5dec414a4f8063
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Sst_(Striatum,_interneuron)\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MESP1 FTCD FASLG	1.83e-04	59	83	3	5da8beaf3c690861d5561ae40d4ff7c2d3732ef4
ToppCell	Globus_pallidus-Neuronal-Inhibitory-iN1(Gad1Gad2_Th)-Inhibitory_Neuron.Gad1Gad2.Sst_(Striatum,_interneuron)--\|Globus_pallidus / BrainAtlas - Mouse McCarroll V32	MESP1 FTCD FASLG	1.83e-04	59	83	3	1c26fabefafd4ce05f21750ae69895c488ea1a11
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-precursor_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SPHKAP LRTM1 SIM2	2.27e-04	160	83	4	c381ec6be8cf887861cc18f831a20db42f953fe1
ToppCell	facs-Marrow-B-cells-24m-Lymphocytic-pre_B_cell\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 SPHKAP LRTM1 SIM2	2.27e-04	160	83	4	25c8f3d2a6d14ff0ca0b965fce89d3ff22f40585
ToppCell	droplet-Liver-Hepatocytes-21m-Epithelial-Hepatocyte_(Pericentral,_Midlobular,_Periportal)\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 FASN LRTM1 FTCD	2.50e-04	164	83	4	90afae3cca108ebfb44ff2ec4adcbb8c68a0bdf2
ToppCell	10x_3'_v2v3-Non-neoplastic-Myeloid-DC-DC1-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	ZNF469 AKNA ARHGAP27 ABCA7	2.62e-04	166	83	4	c8a7d94ed762e5e045ab5f74eef691ddc5f74993
ToppCell	facs-Trachea-18m-Mesenchymal-fibroblast-fibroblast_of_trachea-tracheal_fibroblast_l15\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	IFT140 RBP3 FBLIM1 SSTR3	2.74e-04	168	83	4	a8958b94ffc3423d56c250796dd253884b46f9d9
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC-LEC_mature\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1	2.80e-04	169	83	4	f077e39e41fffe7672541f5b72b80faaf56c597c
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1	2.87e-04	170	83	4	35e3945d8a540a3e2cec1b559316265aaad023d1
ToppCell	PND01-Endothelial-Endothelial_lymphatic\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1	2.87e-04	170	83	4	0ea625abaa25bab93b70b7000e8f90d5c0f9a0fb
ToppCell	PND01-Endothelial-Endothelial_lymphatic-Lymphatic_EC-LEC\|PND01 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	COL18A1 HOXD9 GPR150 DTX1	2.87e-04	170	83	4	0b5ddc7d452db0a389927a367914f7d257703f7e
ToppCell	metastatic_Lymph_Node-Myeloid_cells-Microglia/Mac\|metastatic_Lymph_Node / Location, Cell class and cell subclass	FCGRT CCDC15 KLHL35 ABCA7	3.00e-04	172	83	4	f673a2e697b46e7cfa4186cb3fb2b98e3c83703e
ToppCell	Endothelial-Endothelial-G\|Endothelial / shred on cell class and cell subclass (v4)	COL18A1 HOXD9 FCGRT DTX1	3.00e-04	172	83	4	644f8e42ee8d8996f6ae50cdf874559be55509fc
ToppCell	Immune_cells-Monocytes\|Immune_cells / Lineage and Cell class	FCGRT SAMHD1 ZNF467 IFNAR2	3.06e-04	173	83	4	3eced40a65453a023a1673658592e7e2a099119b
ToppCell	(03)_Secretory-(0)_uninjured\|(03)_Secretory / shred by cell type and Timepoint	FCGRT SLC22A23 MUC16 FBLIM1	3.13e-04	174	83	4	ebdddb5091afcc49ab533c890f260f709880c5f9
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI2 NGEF TEAD1 CSMD1	3.20e-04	175	83	4	b4f01e7782cdd107d0817ef601891fd3a382bc35
ToppCell	droplet-Fat-Bat-18m-Mesenchymal-mesenchymal_stem_cell_of_adipose\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI2 NGEF TEAD1 CSMD1	3.20e-04	175	83	4	ef6f811d8e1839f405c3b41090ddf79be57a099f
ToppCell	droplet-Fat-Bat-18m-Mesenchymal\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MAGI2 NGEF TEAD1 CSMD1	3.20e-04	175	83	4	7f7598d46d10bff1cbea42f950bdde1aaa16e9a4
ToppCell	P15-Endothelial-lymphatic_endothelial_cell-endothelial_cell_of_lymphatic_vessel\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRUNE2 HOXD9 FCGRT DTX1	3.20e-04	175	83	4	84d252f3e432231687613299bbea14978bb4b06b
ToppCell	P15-Endothelial-lymphatic_endothelial_cell\|P15 / developmental_time, Lineage, Cell group, Cell type, Cell type_cellcyc-phase	PRUNE2 HOXD9 FCGRT DTX1	3.20e-04	175	83	4	a00c6fa9b33640710dd05a3799031147196f0986
ToppCell	facs-Trachea-24m-Endothelial-endothelial_cell_of_trachea-tracheal_endothelial_cell-tracheal_endothelial_cell_l54\|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 CASKIN2 DTX1	3.27e-04	176	83	4	460cb302c5b3d609c65b924e1d4e8ea057a68485
ToppCell	wk_08-11-Epithelial-PNS-Late_Schwann\|wk_08-11 / Celltypes from embryonic and fetal-stage human lung	COL18A1 MEGF9 DLX2 SAMHD1	3.41e-04	178	83	4	a7301c0bba03d10feacc02e3f929d9a9235fd25b
ToppCell	3'-GW_trimst-2-LargeIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL18A1 MEGF9 DLX2 SAMHD1	3.56e-04	180	83	4	b294f9db1e2ff51c94cde64fae4c2b057c0030a1
ToppCell	3'-GW_trimst-2-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL18A1 MEGF9 DLX2 SAMHD1	3.56e-04	180	83	4	38490017dd590e3fcfa7e88d8d15235d55f90cf1
ToppCell	RA-16._Neuronal\|RA / Chamber and Cluster_Paper	MICALL2 MEGF9 SLC22A23 SAMHD1	3.56e-04	180	83	4	5842febfdabac61ce970254fb0ef17a628f1b8c0
ToppCell	PCW_10-12-Neuronal-Neuronal_postreplicative\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL18A1 NCAN DLX2 ALK	3.63e-04	181	83	4	1aebb62ed4439db444ee9d30688212b86ee3d9ef
ToppCell	PCW_10-12-Neuronal-Neuronal_postreplicative-neuro_NA\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL18A1 NCAN DLX2 ALK	3.63e-04	181	83	4	6aee2ddee4790250ef3b2ef0038bd9839925c995
ToppCell	PCW_10-12-Neuronal\|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung	COL18A1 NCAN DLX2 ALK	3.63e-04	181	83	4	381b553e2cae65ce6be100662a5f9f963353840c
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXD9 FCGRT LRTM1 SHC3	3.63e-04	181	83	4	b0fff0defba9aea6fba36e378b05a59986e2573a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI2 FRAS1 SIM2	3.63e-04	181	83	4	9d782ba5cf5a172cb4f447763fc50e5b13ef7dd9
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXD9 FCGRT LRTM1 SHC3	3.63e-04	181	83	4	cc77ac0e223e012767222e45c5dcadc246d1aa7c
ToppCell	facs-Lung-18m-Endothelial-lymphatic_endothelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	HOXD9 FCGRT LRTM1 SHC3	3.63e-04	181	83	4	ecd52f33841f4e9d946a4edad0d58da9b0cc5ffa
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NGEF FTCD CSMD1	3.71e-04	182	83	4	e1e58176f533092b6b974ca1ce8b02192a6e193d
ToppCell	PCW_07-8.5-Neuronal-Neuronal_SCP-neuro_pre_proliferating_SCP_(4)\|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung	COL18A1 FRAS1 DLX2 ALK	3.71e-04	182	83	4	bfb725fff3d20066d8ac0a6ba2f88498fcbd876e
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NGEF FTCD CSMD1	3.71e-04	182	83	4	4a9c13932e7163fd37a3dcc4c6ca3bbea5372459
ToppCell	droplet-Heart-HEART_(ALL_MINUS_AORTA)-30m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 SLC22A23 NCAN CSMD1	3.71e-04	182	83	4	812ff2a50a510b18d865e89465dba1754a08ef61
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_3\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI2 FRAS1 SIM2	3.71e-04	182	83	4	eb138aa1dca9373f1586600f258df06dcf56d81f
ToppCell	droplet-Kidney-nan-3m-Epithelial-kidney_collecting_duct_epithelial_cell\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 HOXD9 MEGF9 IDH2	3.71e-04	182	83	4	ccfee33de0faebbe69099d4ff3c3971f6a708b99
ToppCell	wk_15-18-Epithelial-PNS-SST+_neuron\|wk_15-18 / Celltypes from embryonic and fetal-stage human lung	PRUNE2 DLX2 ALK EPHA10	3.71e-04	182	83	4	a7e77aaaddabf78c7784f72b3431703fc5ee4a8c
ToppCell	renal_medulla_nuclei-Adult_normal_reference-Epithelial-Proximal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NGEF FTCD CSMD1	3.71e-04	182	83	4	57bb5a2da976464ba7c4460106bd9f692008ebd9
ToppCell	COVID-19-kidney-PCT-S1\|COVID-19 / Disease (COVID-19 only), tissue and cell type	PRUNE2 FRAS1 NGEF FTCD	3.79e-04	183	83	4	6878d14026c3df6aa12e45dfad94b32fa9d9b0b7
ToppCell	5'-Adult-Appendix-Mesenchymal-fibroblastic-Stromal_1_(ADAMDEC1+)\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MAGI2 COL18A1 KIF26A ZNF467	3.79e-04	183	83	4	5377b4fbd8fdfe68933b4c0965aa9525f7f31591
ToppCell	PND14-Endothelial-Endothelial_blood-vessel-Microvascular_EC-CAP2-CAP2_prolif\|PND14 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	PANK2 MVB12A SLC27A4 EPN2	3.79e-04	183	83	4	3ef9ac1ae13b6172f9121ab1c129ecaa0fef460f
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DISP3 CSMD1 EPHA10	3.87e-04	184	83	4	2cbed6462fea2622871bb7e49b0df3d984239281
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DISP3 CSMD1 EPHA10	3.87e-04	184	83	4	ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCell	facs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	FRAS1 DISP3 CSMD1 EPHA10	3.87e-04	184	83	4	2b19a8c5f823e00812908b23e66bb4e563278aff
ToppCell	Pericytes-Donor_07\|World / lung cells shred on cell class, cell subclass, sample id	COL18A1 FBLIM1 NACAD PALLD	3.87e-04	184	83	4	3d2d55d0f22874be21665ab37da710482f77fc36
ToppCell	3'-Child04-06-SmallIntestine-Mesenchymal-myocytic-myofibroblast_(RSPO2+)\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	PRUNE2 KLHL35 NACAD PALLD	3.87e-04	184	83	4	590fb32bb1f348ea5fa2aece30ebe1e212512991
ToppCell	3'-GW_trimst-1-SmallIntestine-Neuronal-Glial_immature-Glia_1_(DHH+)\|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	COL18A1 MEGF9 DLX2 SAMHD1	3.95e-04	185	83	4	dd17025d8c423aa0a451ac7f1f301c93528e0229
ToppCell	renal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 NGEF FTCD CSMD1	4.03e-04	186	83	4	a417e1e21313a7e05951038cdef5ac672a9f727c
ToppCell	356C-Endothelial_cells-Endothelial-E-\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL18A1 KIF26A CASKIN2 FBLIM1	4.03e-04	186	83	4	2e024097ee361eeb1d855a4edb8ac8cdad35da06
ToppCell	356C-Endothelial_cells-Endothelial-E\|356C / Donor, Lineage, Cell class and subclass (all cells)	COL18A1 KIF26A CASKIN2 FBLIM1	4.03e-04	186	83	4	c3449e54454009973818fc1101933c6f0168258c
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 MAGI2 FRAS1 SIM2	4.03e-04	186	83	4	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	BALF-PFMC-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c05-ZNF683\|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)	ZBTB7A AKNA IDH2 FASLG	4.11e-04	187	83	4	d17352f769c3c66601b65d060626eecff41b0482
ToppCell	human_hepatoblastoma-Tumor_cells-T2\|Tumor_cells / Sample and Cell Type and Tumor Cluster (all cells)	SLC22A23 NGEF FTCD TEAD1	4.11e-04	187	83	4	f3e37c18ac6471c7992609bbddfa4975571c815c
ToppCell	3'_v3-blood\|World / Manually curated celltypes from each tissue	CSF3R KLF13 RIOK3 ZNF467	4.11e-04	187	83	4	9e70e8d7cd8ae517ddf5fd56c69ec16fc33ddff5
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 SLC22A23 DLX2 CSMD1	4.19e-04	188	83	4	921a2c9212a0f2a00fd72c594d80924f27e8b9b7
ToppCell	droplet-Heart-HEART-1m-Neuronal\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 SLC22A23 DLX2 CSMD1	4.28e-04	189	83	4	a618a1ddf5097a010c6c2c7341f3a0bd46a29c02
ToppCell	LPS-IL1RA+antiTNF-Endothelial-Endothelial-Artery\|LPS-IL1RA+antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	KIF26A DISP3 KLHL35 CSMD1	4.28e-04	189	83	4	c45734970036e6d28d5e3fe7c9458fae38a3f624
ToppCell	Somatosensory_Cortex_(S1)-Neuronal-Inh_GABAergic-i_Gaba_1-GABA_L1_LAMP5-Inh_L1_LAMP5_NDNF\|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	COL18A1 FRAS1 SPHKAP ALK	4.28e-04	189	83	4	f0aaf2994d319a39877d2845eaab9f166adead4e
ToppCell	droplet-Heart-HEART-1m-Neuronal-cardiac_neuron\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	COL18A1 SLC22A23 DLX2 CSMD1	4.28e-04	189	83	4	4e61f9cd1c06bddb47ebf98affc0f97770e26e8c
ToppCell	10x_3'_v2v3-Neoplastic-Stem-like-NPC-like-NPC-like_neural-B\|10x_3'_v2v3 / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	KIF26A DTX1 KLHL35 DLX2	4.28e-04	189	83	4	8e6b6025f5554672e26a5d19fe365acb4333789c
ToppCell	E18.5-samps-Mesenchymal\|E18.5-samps / Age Group, Lineage, Cell class and subclass	HOXD9 FCGRT FBLIM1 PALLD	4.28e-04	189	83	4	0c18d3de4720759cf802eefb4d0ddde2a9246a1a
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 MEGF9 SIM2	4.36e-04	190	83	4	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	COVID-19-lung-AT2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	FASN CSF3R MEGF9 SHC3	4.36e-04	190	83	4	27a1a86620fe9b5ee930d388b32352206485e6d0
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	PRUNE2 FRAS1 MEGF9 SIM2	4.36e-04	190	83	4	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 FCGRT DTX1	4.36e-04	190	83	4	a1514d2186eb4fe569971ab22dc0c17d353fb94a
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 FCGRT DTX1	4.36e-04	190	83	4	0bb954a94317cfc742b9b6221bb80f8baa6d3ff1
ToppCell	facs-Lung-3m-Endothelial-lymphatic_endothelial-lymphatic_endothelial_cell-lymphatic_endothelial_cell\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	COL18A1 HOXD9 FCGRT DTX1	4.36e-04	190	83	4	26e2237f65cb43723c5da853831b40df2982d6e4
Drug	Seglitidum [latin]	SSTR3 SSTR5	3.84e-05	3	82	2	CID003035423
Drug	celastrol; Down 200; 2.5uM; MCF7; HT_HG-U133A_EA	IFT140 MEGF9 DIDO1 IDH2 EPN2 IFNAR2	5.91e-05	187	82	6	887_DN
Drug	15d-PGJ2; Down 200; 10uM; MCF7; HT_HG-U133A	ZBTB7A POLG DIDO1 IDH2 ZNF467 FHIP2B	6.84e-05	192	82	6	6990_DN
Drug	Flunisolide [3385-03-3]; Up 200; 9.2uM; PC3; HT_HG-U133A	PRUNE2 FASN KLF13 SORBS3 DVL3 DLX2	6.84e-05	192	82	6	4303_UP
Drug	(d,l)-Tetrahydroberberine [522-97-4]; Down 200; 11.8uM; MCF7; HT_HG-U133A	PRUNE2 IFT140 KLF13 DVL3 SIM2 EPN2	7.04e-05	193	82	6	4138_DN
Drug	Felodipine [72509-76-3]; Down 200; 10.4uM; MCF7; HT_HG-U133A	ZBTB7A IFT140 RANBP3 DIDO1 IDH2 FHIP2B	7.45e-05	195	82	6	3295_DN
Drug	trifluoperazine dihydrochloride; Down 200; 10uM; MCF7; HT_HG-U133A	CASKIN2 RANBP3 POLG IDH2 ZNF467 EPN2	7.45e-05	195	82	6	1649_DN
Drug	3-Acetylcoumarin [3949-36-8]; Down 200; 21.2uM; PC3; HT_HG-U133A	IFT140 MICALL2 IDH2 TEAD1 ZNF467 FHIP2B	7.45e-05	195	82	6	4664_DN
Drug	1,3-dibromoacetone	FASN IDH2	7.65e-05	4	82	2	CID000069952
Drug	Carisoprodol [78-44-4]; Down 200; 15.4uM; PC3; HT_HG-U133A	RALGAPA1 MAN2C1 MICALL2 CASKIN2 IDH2 ZNF467	7.67e-05	196	82	6	6610_DN
Drug	F0447-0125; Down 200; 10uM; MCF7; HT_HG-U133A	PRUNE2 ZBTB7A PER2 KLF13 RANBP3 DLX2	7.67e-05	196	82	6	6396_DN
Drug	Sulfamethizole [144-82-1]; Up 200; 14.8uM; MCF7; HT_HG-U133A	RALGAPA1 PRUNE2 SORBS3 DVL3 SSTR5 KHSRP	7.89e-05	197	82	6	6099_UP
Drug	Doxorubicin hydrochloride [25316-40-9]; Up 200; 6.8uM; PC3; HT_HG-U133A	PRUNE2 MAGI2 RBP3 DLX2 IDH2 ZNF467	7.89e-05	197	82	6	4610_UP
Drug	Methantheline bromide [53-46-3]; Up 200; 9.6uM; HL60; HT_HG-U133A	PRUNE2 COL18A1 SORBS3 SSTR5 EPN2 KHSRP	7.89e-05	197	82	6	6137_UP
Drug	Dimethisoquin hydrochloride [2773-92-4]; Up 200; 13uM; HL60; HT_HG-U133A	FRAS1 SORBS3 SSTR5 FASLG ABCA7 PALLD	7.89e-05	197	82	6	2151_UP
Drug	topiramate; Up 200; 3uM; MCF7; HT_HG-U133A_EA	PRUNE2 IFT140 RANBP3 IDH2 EPN2 IFNAR2	8.11e-05	198	82	6	915_UP
Drug	raloxifene hydrochloride; Up 200; 0.1uM; ssMCF7; HG-U133A	HOXD9 RBBP6 DVL3 KLHL35 ABCA7 PALLD	8.11e-05	198	82	6	376_UP
Drug	Homosalate [118-56-9]; Up 200; 15.2uM; MCF7; HT_HG-U133A	RALGAPA1 PRUNE2 MEGF9 KLF13 RIOK3 ABCA7	8.11e-05	198	82	6	3879_UP
Drug	Sertaconazole nitrate [99592-39-9]; Up 200; 8uM; HL60; HT_HG-U133A	COL18A1 SSTR5 SHC3 PALLD FHIP2B KHSRP	8.57e-05	200	82	6	6128_UP
Drug	Proadifen hydrochloride [62-68-0]; Down 200; 10.2uM; MCF7; HT_HG-U133A	MICALL2 MEGF9 CASKIN2 RANBP3 SAMHD1 ZNF467	8.57e-05	200	82	6	7165_DN
Drug	2-propylpentanoic acid; Up 200; 50uM; HL60; HT_HG-U133A	COL18A1 HOXD9 SOX30 NCAN PALLD EPN2	8.57e-05	200	82	6	6181_UP
Drug	6-thioguanine; Up 200; 10uM; MCF7; HG-U133A	HOXD9 POLG SORBS3 DVL3 KLHL35 ALK	8.57e-05	200	82	6	642_UP
Disease	Childhood Oligodendroglioma	DTX1 IDH2	1.55e-04	7	81	2	C0280475
Disease	Adult Oligodendroglioma	DTX1 IDH2	1.55e-04	7	81	2	C0279070
Disease	Oligodendroblastoma	DTX1 IDH2	1.55e-04	7	81	2	C0344461
Disease	prostate-specific antigen measurement, disease progression measurement	SPHKAP NGEF	1.55e-04	7	81	2	EFO_0008336, EFO_0020660
Disease	Mixed Oligodendroglioma-Astrocytoma	DTX1 IDH2	1.55e-04	7	81	2	C0280793
Disease	Mixed Oligodendroglioma-Ependymoma	DTX1 IDH2	1.55e-04	7	81	2	C0751395
Disease	Well Differentiated Oligodendroglioma	DTX1 IDH2	1.55e-04	7	81	2	C0751396
Disease	oligodendroglioma	DTX1 IDH2	2.06e-04	8	81	2	C0028945
Disease	Anaplastic Oligodendroglioma	DTX1 IDH2	2.06e-04	8	81	2	C0334590
Disease	ulcerative colitis (biomarker_via_orthology)	COL18A1 FASLG	2.65e-04	9	81	2	DOID:8577 (biomarker_via_orthology)
Disease	pursuit maintenance gain measurement	MAGI2 COL18A1 NGEF CSMD1	3.73e-04	123	81	4	EFO_0008433
Disease	hippocampal atrophy	PRUNE2 MAGI2 COL18A1	4.97e-04	56	81	3	EFO_0005039
Disease	ovarian neoplasm	FASN HOXD9 GPR150 MUC16	5.16e-04	134	81	4	C0919267
Disease	Malignant neoplasm of ovary	FASN HOXD9 GPR150 MUC16	5.61e-04	137	81	4	C1140680
Disease	wheezing	MAGI2 KRBA1 ZNF467	7.70e-04	65	81	3	EFO_0009715
Disease	lung cancer (is_implicated_in)	SOX30 DVL3 IDH2	1.12e-03	74	81	3	DOID:1324 (is_implicated_in)
Disease	anthropometric measurement	CCDC91 ZNF469 PER2 TEAD1	1.20e-03	168	81	4	EFO_0004302
Disease	myelodysplastic syndrome (is_marker_for)	CSF3R FASLG	1.37e-03	20	81	2	DOID:0050908 (is_marker_for)
Disease	gastric ulcer (biomarker_via_orthology)	COL18A1 FASLG	1.51e-03	21	81	2	DOID:10808 (biomarker_via_orthology)
Disease	acute myeloid leukemia (is_implicated_in)	CSF3R SAMHD1 IDH2	1.62e-03	84	81	3	DOID:9119 (is_implicated_in)
Disease	physical activity	MAGI2 RBBP6 CSMD1	1.85e-03	88	81	3	EFO_0003940
Disease	eye color	MUC16 SIM2 CSMD1	1.97e-03	90	81	3	EFO_0003949
Disease	Bipolar Disorder	MAGI2 PER2 POLG NCAN CSMD1 SSTR5	2.02e-03	477	81	6	C0005586
Disease	alcohol consumption measurement	MAGI2 MEGF9 KIF26A FCGRT SPHKAP RIOK3 SAMHD1 ARHGAP27 CSMD1 HTT	2.10e-03	1242	81	10	EFO_0007878
Disease	Hypertrophic obstructive cardiomyopathy	FASN IDH2	2.14e-03	25	81	2	C4551472
Disease	epiandrosterone sulfate measurement	ZBTB7A ALK	2.14e-03	25	81	2	EFO_0021120
Disease	pancreatic cancer (is_marker_for)	MUC16 FASLG PALLD	2.74e-03	101	81	3	DOID:1793 (is_marker_for)

Protein segments in the cluster

Peptide	Gene	Start	Entry
ASLPAPWQAVSPGDG	DISP3	851	Q9P2K9
PWEGSAAAAVPATSP	DPEP2NB	16	A0A0U1RQF7
IVSPGNGASWDFPAP	CSMD1	186	Q96PZ7
SWLVSAEGSHPDPAP	DVL3	76	Q92997
ASPPVSAPASWDFGV	DLX2	231	Q07687
LASGNWTPESPSPAC	ABCA7	1331	Q8IZY2
TGTSAWGEPSVPPAA	NUMBL	386	Q9Y6R0
AVPAASPDTAAWRSP	RANBP3	206	Q9H6Z4
WPAPAEETGSSPAGT	MUC16	3181	Q8WXI7
PQPSWGPEAQAASAS	KRBA1	366	A5PL33
APDPVSSQAQWPGSA	LRTM1	236	Q9HBL6
WCATRPSDPASATPG	FRAS1	2831	Q86XX4
DEPAPWSSPAAAAPG	MAGI2	1236	Q86UL8
WSSPAAAAPGLPEVG	MAGI2	1241	Q86UL8
PAASIDPWGVPTGAT	EPN2	386	O95208
TSAATVDPPAWTPSA	MICALL2	396	Q8IY33
AVSSPAPGTPAFWVS	FCGRT	36	P55899
PPLVGLNATAWSPSD	PER2	821	O15055
WRLPSAPSDEASFPG	FHIP2B	321	Q86V87
FWSTARSADGPQGPP	COL18A1	1036	P39060
APGRWVSSSVPASDP	POLG	21	P54098
PAQSPETTPLWATAG	MEGF9	96	Q9H1U4
SASWSAVPSQPPAAA	HOXD9	76	P28356
AWSPGPSVQVSVAPA	KIF26A	196	Q9ULI4
AASPGPSWEAQSFNP	EPHA10	531	Q5JZY3
ASRWNGETEPPAAPA	CASKIN2	1076	Q8WXE0
AALWAAPAAGPAEPA	DTX1	256	Q86Y01
AWSSASAPPPRGFSA	MVB12A	16	Q96EY5
PAASSIWSPASISPG	OTX1	171	P32242
IWSPASISPGSAPAS	OTX1	176	P32242
PAPANLSTPWVSSGV	RBBP6	606	Q7Z6E9
FPSPSSEGLWSEDAP	IFNAR2	481	P48551
AQPFGAEPEAPWGSS	PALLD	781	Q8WX93
REAFGPSPASSDWLP	PANK2	66	Q9BZ23
TTGAAAAASGPWVPP	ATMIN	26	O43313
AWDPVPSLSPATTGA	HTT	2576	P42858
GSRPAWAPAALTAPT	IDH2	16	P48735
SPAIPWAAFPAVSGV	CCDC91	26	Q7Z6B0
WAATPASCAPAQPAG	HOXD12	51	P35452
WEEAGPPSALSSSAP	DIDO1	2041	Q9BTC0
WPGPAEDPQASAASG	AKNA	511	Q7Z591
SVPDPAHSSLGSWVP	CSF3R	661	Q99062
APSPAPATSWSAFSV	MAN2C1	936	Q9NTJ4
SPWTTPGRAAATVPA	FBLIM1	61	Q8WUP2
EGAAAAPPSPAWSEP	KLF13	111	Q9Y2Y9
STTAPAPWAAALAPG	FCRLB	296	Q6BAA4
PPAASSQVWAAGPAA	C1orf127	231	Q8N9H9
QWDPADPAPSALGSA	FASN	1296	P49327
APDAAGSPSFISWHP	IFT140	11	Q96RY7
ADWAPDFGPSSFVPS	FTCD	156	O95954
APPGSQPDYSAAWAE	KHSRP	666	Q92945
GSPASWSFAPLSAAP	RSBN1L	81	Q6PCB5
AAPSGWAQAPLSDTA	VARS2	966	Q5ST30
PDGSDAAPQPGISSW	SPHKAP	456	Q2M3C7
APNPPSSSEESTGSW	SPHKAP	1506	Q2M3C7
TDDGEPAAVAPFPAW	PRUNE2	786	Q8WUY3
AWPPDATLGNVSAGP	SSTR3	21	P32745
TPSNTPSAEADWSPG	SAMHD1	21	Q9Y3Z3
PTTPFATAPWEAAGN	SLC22A23	156	A1A5C7
APAAAAPWSASPGRA	GPR150	266	Q8NGU9
APWSASPGRAPAPSA	GPR150	271	Q8NGU9
EGPSARPATPDLFWS	NCAN	591	O14594
VSAPSPAPWEAFPVA	NCAN	611	O14594
SASVSSGEPTVPWDP	NCAN	941	O14594
SSTPGNGATPEEWPA	NGEF	131	Q8N5V2
GAAAAPLPSPVWETH	ARHGAP27	241	Q6ZUM4
PPQAWPAAVSSAESS	SHC3	431	Q92529
NWRASPPASAAAPPE	SIM2	406	Q14190
EPKPEAAVSPSSWAG	WHAMM	66	Q8TF30
DSWGSTPADSPVASP	MESP1	41	Q9BRJ9
PASTPSWNASSPGAA	SSTR5	6	P35346
GTSFWAAAMEPPPSS	SOX30	26	O94993
EGPCTAPPVTHWAAS	ACD	196	Q96AP0
PGVSWTAGSPAPAEA	ALK	106	Q9UM73
PVGAWVEPASPGSSE	CCDC15	41	Q0P6D6
VASPEPGTAAAWGPS	RIOK3	6	O14730
PQAPSDPCSGWDSDT	PHF13	161	Q86YI8
DPGVPSEWTSPASAG	RALGAPA1	886	Q6GYQ0
GPTETPSWPAPDAAA	RBP3	391	P10745
FCSGSWEPGAVPPST	SLC27A4	201	Q6P1M0
AWVPGSAETSAPAPA	TBC1D10B	61	Q4KMP7
EQRPPAGPASAWSSS	SORBS3	311	O60504
DSSASSPWAPPGTVL	FASLG	16	P48023
DPSSWPPGSVSAVTC	ZNF469	2196	Q96JG9
ASAPAPSVPAWQGRS	TEAD1	196	P28347
PAAWASTPIPARGSF	PVRIG	271	Q6DKI7
WAPPEAQAPSTAGAG	nan	6	Q8N6K4
AAPDAALAAPAWSAP	ZNF467	571	Q7Z7K2
SLPPAAAAAAASFPW	ZBTB7A	171	O95365
SPAQPSSWLSAAFPG	nan	201	Q6ZQT7
ASPPSALAPGDRAWA	nan	71	Q8N3U1
DRAWALPASPSSGAP	nan	81	Q8N3U1
PFSNTWAAAAPLPEA	KLHL35	416	Q6PF15
DDPQPAAEAGTPWAA	NACAD	1001	O15069