Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionPLC activating G protein-coupled glutamate receptor activity

GRM1 GRM5

2.90e-0521082GO:0001639
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity

TGFBR3 BMPR1A BMPR1B

4.23e-05131083GO:0005024
GeneOntologyMolecularFunctionprotein binding involved in heterotypic cell-cell adhesion

NRCAM JUP IZUMO1

1.18e-04181083GO:0086080
GeneOntologyMolecularFunctiontransmembrane receptor protein serine/threonine kinase activity

TGFBR3 BMPR1A BMPR1B

1.64e-04201083GO:0004675
GeneOntologyMolecularFunctionneurotransmitter receptor activity involved in regulation of postsynaptic cytosolic calcium ion concentration

GRM1 GRM5

1.73e-0441082GO:0099583
GeneOntologyMolecularFunctionBMP binding

TGFBR3 BMPR1A BMPR1B

2.20e-04221083GO:0036122
GeneOntologyMolecularFunctionalpha-1,4-glucosidase activity

SI MGAM2

2.87e-0451082GO:0004558
GeneOntologyMolecularFunctionG protein-coupled receptor activity involved in regulation of postsynaptic membrane potential

GRM1 GRM5

2.87e-0451082GO:0099530
GeneOntologyMolecularFunctiontransforming growth factor beta receptor activity, type I

BMPR1A BMPR1B

2.87e-0451082GO:0005025
GeneOntologyMolecularFunctioncell-cell adhesion mediator activity

CLSTN3 NRCAM JUP IZUMO1

3.33e-04611084GO:0098632
GeneOntologyMolecularFunctionalkaline phosphatase activity

ALPI ALPG

4.29e-0461082GO:0004035
GeneOntologyMolecularFunctionantigen binding

IGLV2-23 IGHV8-51-1 IGKV2D-28 KLRD1 IGHV4-4 IGKV2-30

5.88e-041901086GO:0003823
GeneOntologyMolecularFunctionalpha-glucosidase activity

SI MGAM2

5.98e-0471082GO:0090599
GeneOntologyMolecularFunctioncell adhesion mediator activity

CLSTN3 NRCAM JUP IZUMO1

7.70e-04761084GO:0098631
GeneOntologyMolecularFunctionBMP receptor activity

BMPR1A BMPR1B

7.94e-0481082GO:0098821
GeneOntologyMolecularFunctionG protein-coupled glutamate receptor activity

GRM1 GRM5

1.02e-0391082GO:0098988
GeneOntologyMolecularFunctionadenylate cyclase inhibiting G protein-coupled glutamate receptor activity

GRM1 GRM5

1.02e-0391082GO:0001640
GeneOntologyMolecularFunctiontransmembrane receptor protein kinase activity

TGFBR3 BMPR1A BMPR1B TIE1

1.17e-03851084GO:0019199
GeneOntologyBiologicalProcessproduction of molecular mediator of immune response

IGLV3-32 EPG5 MALT1 IGLV2-23 FCRL3 IGKV2D-30 IGKV2D-28 PLCG2 CLNK IGKV2-30 IGKV2-28

1.60e-0540311511GO:0002440
GeneOntologyCellularComponentimmunoglobulin complex

IGLV3-32 IGLV2-23 IGHV8-51-1 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

4.10e-061661168GO:0019814
GeneOntologyCellularComponentreceptor complex

GABRD CRLF1 TSHR GRM1 TGFBR3 BMPR1A BMPR1B TIE1 TRBV7-7 FSHR TRBV5-8 KLRD1 TRAV26-2

2.08e-0558111613GO:0043235
GeneOntologyCellularComponentprotein kinase CK2 complex

CSNK2A1 CSNK2A3

1.82e-0441162GO:0005956
GeneOntologyCellularComponentprotein complex involved in cell-cell adhesion

IZUMO1 GLIPR1L1

4.51e-0461162GO:0098635
GeneOntologyCellularComponentHFE-transferrin receptor complex

BMPR1A BMPR1B

8.36e-0481162GO:1990712
DomainGluR_Homer-bdg

GRM1 GRM5

3.07e-0521042PF10606
DomainMetabotropic_Glu_rcpt_Homer-bd

GRM1 GRM5

3.07e-0521042IPR019588
DomainGPCR_3_mtglu_rcpt_1

GRM1 GRM5

3.07e-0521042IPR001256
DomainGluR_Homer-bdg

GRM1 GRM5

3.07e-0521042SM01229
DomainGPCR_3_mtglu_rcpt_5

GRM1 GRM5

3.07e-0521042IPR000202
DomainAlk_phosphatase

ALPI ALPG

1.83e-0441042PF00245
DomainAlkaline_phosphatase_AS

ALPI ALPG

1.83e-0441042IPR018299
DomainGal_mutarotase_N

SI MGAM2

1.83e-0441042IPR031727
DomainAlkaline_phosphatase

ALPI ALPG

1.83e-0441042IPR001952
DomainNtCtMGAM_N

SI MGAM2

1.83e-0441042PF16863
DomainalkPPc

ALPI ALPG

1.83e-0441042SM00098
DomainALKALINE_PHOSPHATASE

ALPI ALPG

1.83e-0441042PS00123
DomainGlyco_hydro_31_AS

SI MGAM2

4.54e-0461042IPR030458
DomainGphrmn_rcpt_fam

TSHR FSHR

4.54e-0461042IPR002131
DomainGlyco_hydro_31

SI MGAM2

6.33e-0471042IPR000322
DomainGS_dom

BMPR1A BMPR1B

6.33e-0471042IPR003605
DomainGS

BMPR1A BMPR1B

6.33e-0471042PS51256
DomainGlyco_hydro_31

SI MGAM2

6.33e-0471042PF01055
DomainTGF_beta_GS

BMPR1A BMPR1B

6.33e-0471042PF08515
DomainGS

BMPR1A BMPR1B

6.33e-0471042SM00467
DomainGLYCOSYL_HYDROL_F31_1

SI MGAM2

6.33e-0471042PS00129
Domainig

NRCAM MALT1 FCRL3 TIE1 ADGRF5 SIGLEC1

6.81e-041901046PF00047
DomainImmunoglobulin

NRCAM MALT1 FCRL3 TIE1 ADGRF5 SIGLEC1

6.81e-041901046IPR013151
DomainGPCR_3_mtglu_rcpt

GRM1 GRM5

8.41e-0481042IPR000162
DomainTrefoil

SI MGAM2

8.41e-0481042PF00088
DomainP_TREFOIL_2

SI MGAM2

1.08e-0391042PS51448
DomainPD

SI MGAM2

1.08e-0391042SM00018
DomainANF_lig-bd_rcpt

GRM1 GRM5 GUCY2F

1.14e-03371043IPR001828
DomainANF_receptor

GRM1 GRM5 GUCY2F

1.14e-03371043PF01094
DomainPeripla_BP_I

GRM1 GRM5 GUCY2F

1.33e-03391043IPR028082
DomainLRR_5

TSHR FSHR

1.34e-03101042PF13306
DomainLRR_5

TSHR FSHR

1.34e-03101042IPR026906
DomainAllrgn_V5/Tpx1_CS

CRISP2 GLIPR1L1

1.34e-03101042IPR018244
DomainActivin_recp

BMPR1A BMPR1B

1.34e-03101042PF01064
DomainActivin_recp

BMPR1A BMPR1B

1.34e-03101042IPR000472
Domain-

SI MGAM2

1.63e-031110424.10.110.10
DomainCRISP_1

CRISP2 GLIPR1L1

1.63e-03111042PS01009
DomainCRISP_2

CRISP2 GLIPR1L1

1.63e-03111042PS01010
DomainTGFB_receptor

BMPR1A BMPR1B

1.95e-03121042IPR000333
DomainP_trefoil_dom

SI MGAM2

1.95e-03121042IPR000519
DomainNCD3G

GRM1 GRM5

2.30e-03131042PF07562
DomainGPCR_3_9-Cys_dom

GRM1 GRM5

2.30e-03131042IPR011500
Domain-

CASP10 MALT1

2.68e-031410423.40.50.1460
DomainPept_C14_p20

CASP10 MALT1

2.68e-03141042IPR001309
DomainCaspase-like_dom

CASP10 MALT1

2.68e-03141042IPR029030
DomainCASPASE_P20

CASP10 MALT1

2.68e-03141042PS50208
DomainGPCR_3_CS

GRM1 GRM5

2.68e-03141042IPR017979
DomainCAP

CRISP2 GLIPR1L1

3.08e-03151042PF00188
DomainSCP

CRISP2 GLIPR1L1

3.08e-03151042SM00198
DomainAllrgn_V5/Tpx1

CRISP2 GLIPR1L1

3.08e-03151042IPR001283
Domain-

CRISP2 GLIPR1L1

3.08e-031510423.40.33.10
DomainCAP_domain

CRISP2 GLIPR1L1

3.08e-03151042IPR014044
DomainGlycoside_hydrolase_SF

SI HPSE MGAM2

3.21e-03531043IPR017853
DomainCADHERIN_1

CLSTN3 PCDHGB3 PCDHA10 CDH18

3.67e-031131044PS00232
DomainCadherin

CLSTN3 PCDHGB3 PCDHA10 CDH18

3.67e-031131044PF00028
DomainFN3

PAPPA2 CRLF1 NRCAM TRIM42 TIE1

3.77e-031851045SM00060
DomainCADHERIN_2

CLSTN3 PCDHGB3 PCDHA10 CDH18

3.79e-031141044PS50268
Domain-

CLSTN3 PCDHGB3 PCDHA10 CDH18

3.79e-0311410442.60.40.60
Domain-

PAPPA2 CRLF1 NRCAM TRIM42 MALT1 FCRL3 TIE1 IZUMO1 ADGRF5 SIGLEC1

3.87e-03663104102.60.40.10
DomainCA

CLSTN3 PCDHGB3 PCDHA10 CDH18

3.91e-031151044SM00112
DomainGal_mutarotase_SF_dom

SI MGAM2

3.95e-03171042IPR011013
DomainCadherin-like

CLSTN3 PCDHGB3 PCDHA10 CDH18

4.03e-031161044IPR015919
DomainCadherin

CLSTN3 PCDHGB3 PCDHA10 CDH18

4.28e-031181044IPR002126
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28 PLD4

6.45e-0782867M27110
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

1.38e-0586866M601
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

1.38e-0586866M27206
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

1.47e-0587866M27205
PathwayREACTOME_ROLE_OF_PHOSPHOLIPIDS_IN_PHAGOCYTOSIS

IGKV2D-28 PLCG2 IGHV4-4 IGKV2-28 PLD4

2.25e-0556865MM14815
PathwayREACTOME_FCGR3A_MEDIATED_IL10_SYNTHESIS

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

2.43e-0595866M29842
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28 PLD4

2.63e-05143867M27107
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

3.42e-0561865M27581
PathwayREACTOME_FCGR_ACTIVATION

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

6.21e-0569865M27108
PathwayREACTOME_SCAVENGING_OF_HEME_FROM_PLASMA

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

6.21e-0569865M27150
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

MALT1 IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

6.81e-05166867M608
PathwayREACTOME_CREATION_OF_C4_AND_C2_ACTIVATORS

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

7.13e-0571865M1078
PathwayREACTOME_ROLE_OF_LAT2_NTAL_LAB_ON_CALCIUM_MOBILIZATION

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

7.13e-0571865M27203
PathwayREACTOME_INITIAL_TRIGGERING_OF_COMPLEMENT

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

1.26e-0480865M6121
PathwayREACTOME_FC_EPSILON_RECEPTOR_FCERI_SIGNALING

MALT1 IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

1.39e-04186867M27175
PathwayREACTOME_IMMUNOREGULATORY_INTERACTIONS_BETWEEN_A_LYMPHOID_AND_A_NON_LYMPHOID_CELL

IGLV2-23 IGKV2D-30 IGKV2D-28 SIGLEC1 KLRD1 IGKV2-30 IGKV2-28

1.58e-04190867M8240
PathwayREACTOME_ANTI_INFLAMMATORY_RESPONSE_FAVOURING_LEISHMANIA_PARASITE_INFECTION

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

1.66e-04134866M29840
PathwayREACTOME_FCERI_MEDIATED_NF_KB_ACTIVATION

MALT1 IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

1.80e-04136866M27207
PathwayREACTOME_DIGESTION

SI ALPI ALPG

2.69e-0421863MM15526
PathwayREACTOME_ANTIGEN_ACTIVATES_B_CELL_RECEPTOR_BCR_LEADING_TO_GENERATION_OF_SECOND_MESSENGERS

IGKV2D-28 PLCG2 IGHV4-4 IGKV2-28

3.01e-0453864MM15716
PathwayREACTOME_BINDING_AND_UPTAKE_OF_LIGANDS_BY_SCAVENGER_RECEPTORS

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

3.27e-0498865M27152
PathwayREACTOME_POTENTIAL_THERAPEUTICS_FOR_SARS

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

3.53e-04154866M39007
PathwayREACTOME_FCERI_MEDIATED_CA_2_MOBILIZATION

IGKV2D-28 PLCG2 IGHV4-4 IGKV2-28

4.26e-0458864MM14914
PathwayREACTOME_DIGESTION_AND_ABSORPTION

SI ALPI ALPG

4.58e-0425863MM15557
PathwayREACTOME_FCERI_MEDIATED_MAPK_ACTIVATION

IGKV2D-28 PLCG2 IGHV4-4 IGKV2-28

4.85e-0460864MM14913
PathwayREACTOME_FCGAMMA_RECEPTOR_FCGR_DEPENDENT_PHAGOCYTOSIS

IGKV2D-28 PLCG2 IGHV4-4 IGKV2-28 PLD4

6.55e-04114865MM14814
PathwayWP_PRIMARY_OVARIAN_INSUFFICIENCY

TG TGFBR3 BMPR1A BMPR1B FSHR TRIM37

6.74e-04174866M48058
PathwayREACTOME_COMPLEMENT_CASCADE

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

6.82e-04115865M19752
PathwayREACTOME_PARASITE_INFECTION

IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

7.09e-04116865M29843
PathwayREACTOME_SIGNALING_BY_BMP

TGFBR3 BMPR1A BMPR1B

8.71e-0431863M1662
PathwayREACTOME_SIGNALING_BY_BMP

TGFBR3 BMPR1A BMPR1B

8.71e-0431863MM14789
PathwayREACTOME_SIGNALING_BY_THE_B_CELL_RECEPTOR_BCR

MALT1 IGKV2D-28 PLCG2 IGHV4-4 IGKV2-28

1.22e-03131865MM15717
PathwayREACTOME_CD22_MEDIATED_BCR_REGULATION

IGKV2D-28 IGHV4-4 IGKV2-28

1.25e-0335863MM17219
PathwayKEGG_MEDICUS_REFERENCE_AMH_SIGNALING_PATHWAY

BMPR1A BMPR1B

1.29e-039862M47844
PathwayREACTOME_CLASSICAL_ANTIBODY_MEDIATED_COMPLEMENT_ACTIVATION

IGKV2D-28 IGHV4-4 IGKV2-28

1.71e-0339863MM17212
PathwayWP_MICROGLIA_PATHOGEN_PHAGOCYTOSIS_PATHWAY

CYBB PIK3C2A PLCG2

1.84e-0340863M39695
PathwayKEGG_FOLATE_BIOSYNTHESIS

ALPI ALPG

1.95e-0311862M2220
Pubmed

The transforming growth factor-beta type III receptor mediates distinct subcellular trafficking and downstream signaling of activin-like kinase (ALK)3 and ALK6 receptors.

TGFBR3 BMPR1A BMPR1B

3.71e-083117319726563
Pubmed

Clinical associations of the genetic variants of CTLA-4, Tg, TSHR, PTPN22, PTPN12 and FCRL3 in patients with Graves' disease.

TSHR TG FCRL3

3.69e-075117319438904
Pubmed

Bone morphogenetic proteins signal through the transforming growth factor-beta type III receptor.

TGFBR3 BMPR1A BMPR1B

3.69e-075117318184661
Pubmed

Functional roles of Lgr4 and Lgr5 in embryonic gut, kidney and skin development in mice.

VIL1 SI ALPI ALPG

1.03e-0623117424680895
Pubmed

The human immunoglobulin kappa locus. Characterization of the duplicated A regions.

IGKV2D-30 IGKV2-30 IGKV2-28

4.38e-061011731551402
Pubmed

Casein kinase 2 (CK2) phosphorylates the deubiquitylase OTUB1 at Ser16 to trigger its nuclear localization.

BMPR1A BMPR1B CSNK2A1

7.98e-0612117325872870
Pubmed

Large-scale discovery of mouse transgenic integration sites reveals frequent structural variation and insertional mutagenesis.

MCPH1 EDIL3 CDH18

7.98e-0612117330659012
Pubmed

Thyroid follicle development requires Smad1/5- and endothelial cell-dependent basement membrane assembly.

TG BMPR1A BMPR1B TIE1

1.01e-0540117427068110
Pubmed

Studies of the interactions between the anticytokeratin 8 monoclonal antibody TS1, its antigen and its anti-idiotypic antibody alphaTS1.

IGKV2D-28 IGKV2-28

1.12e-052117212833571
Pubmed

Cyclic ADP ribose-dependent Ca2+ release by group I metabotropic glutamate receptors in acutely dissociated rat hippocampal neurons.

GRM1 GRM5

1.12e-052117222028929
Pubmed

Mice lacking metabotropic glutamate receptor 5 show impaired learning and reduced CA1 long-term potentiation (LTP) but normal CA3 LTP.

GRM1 GRM5

1.12e-05211729185557
Pubmed

Two V kappa germ-line genes related to the GAT idiotypic network (Ab1 and Ab3/Ab1') account for the major subfamilies of the mouse V kappa-1 variability subgroup.

IGKV2D-28 IGKV2-28

1.12e-05211723100621
Pubmed

Assignment of the BMPR1A and BMPR1B genes to human chromosome 10q22.3 and 4q23-->q24 byin situ hybridization and radiation hybrid map ping.

BMPR1A BMPR1B

1.12e-05211729730621
Pubmed

Structural and affinity studies of IgM polyreactive natural autoantibodies.

IGKV2D-28 IGKV2-28

1.12e-05211728993018
Pubmed

Expression of bone morphogenetic protein receptors type-IA, -IB and -II correlates with tumor grade in human prostate cancer tissues.

BMPR1A BMPR1B

1.12e-052117210850425
Pubmed

Three-dimensional atomic structure of a catalytic subunit mutant of human protein kinase CK2.

CSNK2A1 CSNK2A3

1.12e-052117214646071
Pubmed

Differential molecular regulation of processing and membrane expression of Type-I BMP receptors: implications for signaling.

BMPR1A BMPR1B

1.12e-052117228357470
Pubmed

mGluR₁,5 activation improves network asynchrony and GABAergic synapse attenuation in the amygdala: implication for anxiety-like behavior in DBA/2 mice.

GRM1 GRM5

1.12e-052117222681774
Pubmed

Distinct roles of BMP receptors Type IA and IB in osteo-/chondrogenic differentiation in mesenchymal progenitors (C3H10T1/2).

BMPR1A BMPR1B

1.12e-052117215322331
Pubmed

mGluR1,5 activation protects cortical astrocytes and GABAergic neurons from ischemia-induced impairment.

GRM1 GRM5

1.12e-052117223280324
Pubmed

V genes of oxazolone antibodies in 10 strains of mice.

IGKV2D-28 IGKV2-28

1.12e-05211721936125
Pubmed

Metabotropic glutamate receptors in the main olfactory bulb drive granule cell-mediated inhibition.

GRM1 GRM5

1.12e-052117217093122
Pubmed

Crystal structure of a C-terminal deletion mutant of human protein kinase CK2 catalytic subunit.

CSNK2A1 CSNK2A3

1.12e-052117212860116
Pubmed

Influence of the hinge region and its adjacent domains on binding and signaling patterns of the thyrotropin and follitropin receptor.

TSHR FSHR

1.12e-052117225340405
Pubmed

BMPR1A is necessary for chondrogenesis and osteogenesis, whereas BMPR1B prevents hypertrophic differentiation.

BMPR1A BMPR1B

1.12e-052117232764110
Pubmed

[BMP7 signaling via BMPR1A, BMPR1B inhibits the proliferation of lung large carcinoma NCI-H460 cell].

BMPR1A BMPR1B

1.12e-052117220673479
Pubmed

Nucleotide sequences of the variable regions of a mouse monoclonal antibody MRK16.

IGKV2D-28 IGKV2-28

1.12e-05211722110659
Pubmed

In-vivo genetic ablation of metabotropic glutamate receptor type 5 slows down disease progression in the SOD1G93A mouse model of amyotrophic lateral sclerosis.

GRM1 GRM5

1.12e-052117231102766
Pubmed

The effect of ovarian reserve and receptor signalling on granulosa cell apoptosis during human follicle development.

BMPR1B FSHR

1.12e-052117229113831
Pubmed

Corticostriatal LTP requires combined mGluR1 and mGluR5 activation.

GRM1 GRM5

1.12e-052117212559117
Pubmed

Involvement of group I metabotropic glutamate receptors and glutamate transporters in the slow excitatory synaptic transmission in the spinal cord dorsal horn.

GRM1 GRM5

1.12e-052117218554818
Pubmed

Group 1 metabotropic glutamate receptors 1 and 5 form a protein complex in mouse hippocampus and cortex.

GRM1 GRM5

1.12e-052117227392515
Pubmed

Epithelial Bmpr1a regulates differentiation and proliferation in postnatal hair follicles and is essential for tooth development.

BMPR1A BMPR1B

1.12e-052117215102710
Pubmed

Genetic inactivation of mGlu5 receptor improves motor coordination in the Grm1crv4 mouse model of SCAR13 ataxia.

GRM1 GRM5

1.12e-052117228982591
Pubmed

Risk of non-medullary thyroid cancer influenced by polymorphic variation in the thyroglobulin gene.

TSHR TG

1.12e-052117214633662
Pubmed

Assignment of casein kinase 2 alpha sequences to two different human chromosomes.

CSNK2A1 CSNK2A3

1.12e-05211721577469
Pubmed

Cryoglobulinemia induced by a murine IgG3 rheumatoid factor: skin vasculitis and glomerulonephritis arise from distinct pathogenic mechanisms.

IGKV2D-28 IGKV2-28

1.12e-05211722263605
Pubmed

IgM binding to injured tissue precedes complement activation during skeletal muscle ischemia-reperfusion.

IGKV2D-28 IGKV2-28

1.12e-052117215522311
Pubmed

Human fibrocytes coexpress thyroglobulin and thyrotropin receptor.

TSHR TG

1.12e-052117222517745
Pubmed

Selective induction of metabotropic glutamate receptor 1- and metabotropic glutamate receptor 5-dependent chemical long-term potentiation at oriens/alveus interneuron synapses of mouse hippocampus.

GRM1 GRM5

1.12e-052117218035501
Pubmed

Determination of group I metabotropic glutamate receptor subtypes involved in the frequency of epileptiform activity in vitro using mGluR1 and mGluR5 mutant mice.

GRM1 GRM5

1.12e-052117212623213
Pubmed

Group I metabotropic glutamate receptors mediate a dual role of glutamate in T cell activation.

GRM1 GRM5

1.12e-052117215184389
Pubmed

No evidence for a direct extracellular interaction between human Fc receptor-like 3 (MAIA) and the sperm ligand IZUMO1.

FCRL3 IZUMO1

1.12e-052117238381819
Pubmed

Early induced IgM as a predictor and risk factor for severe disease outcome after West Nile virus infection.

IGKV2D-28 IGKV2-28

1.12e-052117215219549
Pubmed

Metabotropic glutamate receptor 5 mediates the potentiation of N-methyl-D-aspartate responses in medium spiny striatal neurons.

GRM1 GRM5

1.12e-052117211591458
Pubmed

Amino acid sequence of the light chain variable region from a mouse anti-digoxin hybridoma antibody.

IGKV2D-28 IGKV2-28

1.12e-05211726404298
Pubmed

BMPR1A and BMPR1B Missense Mutations Cause Primary Ovarian Insufficiency.

BMPR1A BMPR1B

1.12e-052117231769494
Pubmed

Symmetric signal transduction and negative allosteric modulation of heterodimeric mGlu1/5 receptors.

GRM1 GRM5

1.12e-052117233279506
Pubmed

Molecular cloning of the human casein kinase II alpha subunit.

CSNK2A1 CSNK2A3

1.12e-05211722752008
Pubmed

Structure and sequence of an intronless gene for human casein kinase II-alpha subunit.

CSNK2A1 CSNK2A3

1.12e-05211728420794
Pubmed

mGluR5 Is Substitutable for mGluR1 in Cerebellar Purkinje Cells for Motor Coordination, Developmental Synapse Elimination, and Motor Learning.

GRM1 GRM5

1.12e-052117235805089
Pubmed

Decreased degradation of internalized follicle-stimulating hormone caused by mutation of aspartic acid 6.30(550) in a protein kinase-CK2 consensus sequence in the third intracellular loop of human follicle-stimulating hormone receptor.

CSNK2A1 FSHR

1.12e-052117221270425
Pubmed

Enhanced Function and Overexpression of Metabotropic Glutamate Receptors 1 and 5 in the Spinal Cord of the SOD1G93A Mouse Model of Amyotrophic Lateral Sclerosis during Disease Progression.

GRM1 GRM5

1.12e-052117231540330
Pubmed

Differential distribution of group I metabotropic glutamate receptors in developing human cortex.

GRM1 GRM5

1.12e-052117220149785
Pubmed

Opposing Fgf and Bmp activities regulate the specification of olfactory sensory and respiratory epithelial cell fates.

BMPR1A BMPR1B HES5

1.31e-0514117320392740
Pubmed

Activation of pre-mRNA splicing by human RNPS1 is regulated by CK2 phosphorylation.

CSNK2A1 CSNK2A3

3.36e-053117215684395
Pubmed

Calcineurin inhibitor protein (CAIN) attenuates Group I metabotropic glutamate receptor endocytosis and signaling.

GRM1 GRM5

3.36e-053117219717561
Pubmed

TSH stimulation of human thyroglobulin and thyroid peroxidase gene transcription is partially dependent on internalization.

TSHR TG

3.36e-053117234896620
Pubmed

Isolation and characterization of human cDNA clones encoding the alpha and the alpha' subunits of casein kinase II.

CSNK2A1 CSNK2A3

3.36e-05311722174700
Pubmed

Age-Associated Increase in BMP Signaling Inhibits Hippocampal Neurogenesis.

BMPR1A BMPR1B

3.36e-053117225538007
Pubmed

Role of synaptic metabotropic glutamate receptors in epileptiform discharges in hippocampal slices.

GRM1 GRM5

3.36e-053117212364493
Pubmed

Dendrite complexity of sympathetic neurons is controlled during postnatal development by BMP signaling.

BMPR1A BMPR1B

3.36e-053117224048844
Pubmed

Distinct developmental programs require different levels of Bmp signaling during mouse retinal development.

BMPR1A BMPR1B

3.36e-053117215673568
Pubmed

Mapping of the human casein kinase II catalytic subunit genes: two loci carrying the homologous sequences for the alpha subunit.

CSNK2A1 CSNK2A3

3.36e-05311721766873
Pubmed

Tyrosine sulfation is required for agonist recognition by glycoprotein hormone receptors.

TSHR FSHR

3.36e-053117211847099
Pubmed

Expression patterns of BMPRs in the developing mouse molar.

BMPR1A BMPR1B

3.36e-053117216432712
Pubmed

Analysis of the native murine bone morphogenetic protein serine threonine kinase type I receptor (ALK-3).

BMPR1A BMPR1B

3.36e-05311728707881
Pubmed

Iodinated TG in Thyroid Follicles Regulate TSH/TSHR Signaling for NIS Expression.

TSHR TG

3.36e-053117228396984
Pubmed

Glycoprotein hormone receptors: link between receptor homodimerization and negative cooperativity.

TSHR FSHR

3.36e-053117215889138
Pubmed

The mode of bone morphogenetic protein (BMP) receptor oligomerization determines different BMP-2 signaling pathways.

BMPR1A BMPR1B

3.36e-053117211714695
Pubmed

Transdifferentiation of alveolar epithelial type II to type I cells is controlled by opposing TGF-β and BMP signaling.

BMPR1A BMPR1B

3.36e-053117223831617
Pubmed

The type I BMP receptor ACVR1/ALK2 is required for chondrogenesis during development.

BMPR1A BMPR1B

3.36e-053117225413979
Pubmed

Granulosa cell-expressed BMPR1A and BMPR1B have unique functions in regulating fertility but act redundantly to suppress ovarian tumor development.

BMPR1A BMPR1B

3.36e-053117220363875
Pubmed

Distinct regulatory functions of SLP-76 and MIST in NK cell cytotoxicity and IFN-gamma production.

PLCG2 CLNK

3.36e-053117218203684
Pubmed

Crystallization and preliminary characterization of crystals of human protein kinase CK2.

CSNK2A1 CSNK2A3

3.36e-053117211092945
Pubmed

Organic pyrophosphates as substrates for human alkaline phosphatases.

ALPI ALPG

3.36e-053117216742561
Pubmed

BMP signaling specifies the development of a large and fast CNS synapse.

BMPR1A BMPR1B

3.36e-053117223708139
Pubmed

Distinct spatial and temporal expression patterns of two type I receptors for bone morphogenetic proteins during mouse embryogenesis.

BMPR1A BMPR1B

3.36e-05311727750489
Pubmed

Sequencing of full-length cDNA encoding the alpha and beta subunits of human casein kinase II from human platelets and megakaryocytic cells. Expression of the casein kinase IIalpha intronless gene in a megakaryocytic cell line.

CSNK2A1 CSNK2A3

3.36e-053117212102635
Pubmed

BMPR1a and BMPR1b signaling exert opposing effects on gliosis after spinal cord injury.

BMPR1A BMPR1B

3.36e-053117220130193
Pubmed

Homology between TSH-R/Tg/TPO and Hashimoto's encephalopathy autoantigens.

TSHR TG

3.36e-053117231585887
Pubmed

Functional polymorphism of the CK2alpha intronless gene plays oncogenic roles in lung cancer.

CSNK2A1 CSNK2A3

3.36e-053117220625391
Pubmed

Bone morphogenetic protein type IB receptor is progressively expressed in malignant glioma tumours.

BMPR1A BMPR1B

3.36e-05311728605097
Pubmed

Two gene duplication events in the evolution of the human heat-stable alkaline phosphatases.

ALPI ALPG

3.36e-05311723443302
Pubmed

Role of type I receptors for anti-Müllerian hormone in the SMAT-1 Sertoli cell line.

BMPR1A BMPR1B

3.36e-053117215897891
Pubmed

Soluble LR11/SorLA represses thermogenesis in adipose tissue and correlates with BMI in humans.

BMPR1A BMPR1B

3.36e-053117226584636
Pubmed

Structural predictions for the ligand-binding region of glycoprotein hormone receptors and the nature of hormone-receptor interactions.

TSHR FSHR

3.36e-05311728747461
Pubmed

SIRT1 Activation Attenuates Bone Cancer Pain by Inhibiting mGluR1/5.

GRM1 GRM5

3.36e-053117231270711
Pubmed

Expression of bone morphogenetic protein receptors in the developing mouse metanephros.

BMPR1A BMPR1B

3.36e-053117211701996
Pubmed

Enhanced endocannabinoid signaling elevates neuronal excitability in fragile X syndrome.

GRM1 GRM5

3.36e-053117220410124
Pubmed

The regulation of hippocampal LTP by the molecular switch, a form of metaplasticity, requires mGlu5 receptors.

GRM1 GRM5

3.36e-053117216024054
Pubmed

Role of lysophosphatidylcholine in brush-border intestinal alkaline phosphatase release and restoration.

ALPI ALPG

3.36e-053117219407215
Pubmed

Genomic structure and comparison of mouse tissue-specific alkaline phosphatase genes.

ALPI ALPG

3.36e-05311722286375
Pubmed

GLIPR1L1 is an IZUMO-binding protein required for optimal fertilization in the mouse.

IZUMO1 GLIPR1L1

3.36e-053117231672133
Pubmed

mGluR1 and mGluR5 Synergistically Control Cholinergic Synaptic Transmission in the Thalamic Reticular Nucleus.

GRM1 GRM5

3.36e-053117227466334
Pubmed

Genetic reduction of group 1 metabotropic glutamate receptors alters select behaviors in a mouse model for fragile X syndrome.

GRM1 GRM5

3.36e-053117221571007
Pubmed

Intestinal Alkaline Phosphatase Regulates Tight Junction Protein Levels.

ALPI ALPG

3.36e-053117227106638
Pubmed

Characterization and reversal of synaptic defects in the amygdala in a mouse model of fragile X syndrome.

GRM1 GRM5

3.36e-053117220534533
Pubmed

Effects of disruption of the embryonic alkaline phosphatase gene on preimplantation development of the mouse.

ALPI ALPG

3.36e-053117210767088
Pubmed

MUSEAP, a novel reporter gene for the study of long-term gene expression in immunocompetent mice.

ALPI ALPG

3.36e-053117211722850
Cytoband6q24

GRM1 UTRN

1.79e-04811726q24
Cytoband2p12

IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

2.38e-0411711742p12
CytobandEnsembl 112 genes in cytogenetic band chr2q37

UGT1A6 SH3BP4 ANO7 ALPI ALPG

2.96e-042261175chr2q37
GeneFamilyGlycoprotein hormone receptors

TSHR FSHR

6.23e-053832199
GeneFamilyAlkaline phosphatases

ALPI ALPG

1.24e-0448321072
GeneFamilyType 1 receptor serine/threonine kinases

BMPR1A BMPR1B

4.31e-047832345
GeneFamilyGlutamate metabotropic receptors|Protein phosphatase 1 regulatory subunits

GRM1 GRM5

5.73e-048832281
GeneFamilyImmunoglobulin kappa locus at 2p11.2

IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

5.76e-0483834351
GeneFamilyPhospholipases

PLB1 PLCG2 PLD4

9.41e-0442833467
GeneFamilyTubulin tyrosine ligase family

TTLL8 TTLL6

1.83e-0314832779
GeneFamilyImmunoglobulin like domain containing

NRCAM MALT1 FCRL3 TIE1 ADGRF5

1.95e-03193835594
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500_k-means-cluster#3

SOX3 SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

6.00e-071391098Arv_SC_fibroblast_500_K3
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500_k-means-cluster#2

CH25H SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28

2.00e-061631098Arv_SC-hpx_blastocyst_500_K2
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500_k-means-cluster#3

CH25H SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28

3.39e-061751098Arv_SC-H9hpx_500_K3
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_500_k-means-cluster#2

SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

3.95e-061261097Arv_SC-HD_500_K2
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000_k-means-cluster#5

SOX3 SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28

4.73e-061831098Arv_SC_fibroblast_1000_K5
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000_k-means-cluster#3

SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 ALPI IGKV2-28

4.73e-061831098Arv_SC-HD_1000_K3
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000

SOX3 VIL1 HECW1 CH25H SI CLDN7 ERVMER34-1 IGLV2-23 TTLL6 GLIPR1L1 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28 SMTNL2 ALPG

1.11e-0598710917Arv_SC-H9hpx_1000
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_1000

SOX3 VIL1 HECW1 CH25H SI CLDN7 ERVMER34-1 IGLV2-23 TTLL6 GLIPR1L1 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28 SMTNL2 ALPG

1.11e-0598710917Arv_SC-hpx_blastocyst_1000
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_1000_k-means-cluster#4

CH25H SI IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28

3.79e-052441098Arv_SC-H9hpx_1000_K4
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_500

SOX3 VIL1 SI ERVMER34-1 IGLV2-23 TTLL6 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

4.35e-0548910911Arv_SC-HD_500
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_500

SOX3 VIL1 SI ERVMER34-1 IGLV2-23 TTLL6 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

4.35e-0548910911Arv_SC_fibroblast_500
CoexpressionAtlasAravindRamakr_StemCell_from_inducedPluripotentialStemCells_derived from_from_fibroblast_top-relative-expression-ranked_1000

SOX3 VIL1 SI ERVMER34-1 IGLV2-23 MALRD1 TTLL6 GLIPR1L1 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 ALPI IGKV2-28 SMTNL2

1.54e-0498610915Arv_SC_fibroblast_1000
CoexpressionAtlasAravindRamakr_StemCell-HD_top-relative-expression-ranked_1000

SOX3 VIL1 SI ERVMER34-1 IGLV2-23 MALRD1 TTLL6 GLIPR1L1 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 ALPI IGKV2-28 SMTNL2

1.54e-0498610915Arv_SC-HD_1000
CoexpressionAtlasAravindRamakr_StemCell-H9hpx_top-relative-expression-ranked_500

SOX3 CH25H SI IGLV2-23 GLIPR1L1 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28

2.24e-0449210910Arv_SC-H9hpx_500
CoexpressionAtlasAravindRamakr_StemCell-hypoxiaGrown_fromBlastocyst-derived-humanEmbryonicStemCells_top-relative-expression-ranked_500

SOX3 CH25H SI IGLV2-23 GLIPR1L1 IGKV2D-30 IGKV2D-28 IGKV2-30 ALPI IGKV2-28

2.24e-0449210910Arv_SC-hpx_blastocyst_500
ToppCellrenal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Collecting_tubule_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A NAALADL2 SH3BP4 JUP BMPR1B ADGRF5 SMS PLCG2 CLNK

1.85e-091921159f7e7491426bbd6ed29a465b58bf67acb93dbb90a
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

AFF3 IGLV2-23 FCRL3 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 PLD4

2.41e-081811158700adfb41e4e377530f0dd31be89e12f109f3469
ToppCellIPF-Myeloid-DC_Langerhans|IPF / Disease state, Lineage and Cell class

PALD1 NRCAM AFF3 SLC2A1 MALT1 GPR137B CLNK PLD4

2.85e-081851158f8ee3cb2aa9ec70f9ce8797be2b155da27ef6464
ToppCellIPF-Myeloid-DC_Langerhans|Myeloid / Disease state, Lineage and Cell class

PALD1 NRCAM AFF3 SLC2A1 MALT1 GPR137B CLNK PLD4

2.85e-081851158ced17f69486591c3cbbdc852a3e82c3f3a4a30d7
ToppCellCOPD-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 MALT1 GPR137B CLNK PLD4

2.00e-0716011571b73a14ad6546d9f2812c19081278a79260abeae
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

AFF3 TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

4.12e-071781157107dae8b00c4257697a63700e72bb434cdb8406f
ToppCellIPF-Myeloid-DC_Langerhans|World / Disease state, Lineage and Cell class

PALD1 NRCAM AFF3 SLC2A1 GPR137B CLNK PLD4

4.79e-0718211570e8cfbd8ea196f27a227dbb4d2eb93bc48d27922
ToppCellTracheal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PCDHGB3 IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

7.61e-071951157df009b18898c10686f75cf72b4ec0eff18f5bb50
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PALD1 CH25H CASP10 CLDN7 MELTF PLCG2 SLC12A7

9.02e-07200115725f4c051c2e869481f33c22ad54de97efac444ad
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW16-Neuroepithelial-Proteoglycan-expressing_cell|GW16 / Sample Type, Dataset, Time_group, and Cell type.

PALD1 CH25H CASP10 CLDN7 MELTF PLCG2 SLC12A7

9.02e-072001157da45a85a4667965b24ba824af871157af5b4cd19
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell-kidney_collecting_duct_intercalated_cell-Transitional_Principal-Intercalated_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A NRCAM BMPR1B ADGRF5 PLCG2 CLNK

1.74e-061401156e64f6aa57bc069cfe970089bd1c298433bfaf771
ToppCellfacs-Trachea-24m-Hematologic-myeloid-tracheal_macrophage-macrophage_of_trachea|24m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

CYBB KCNH7 GRM5 MALT1 PLCG2 PLD4

2.80e-061521156931c10245cde9b3290224cc1da46b2bf300b9ac2
ToppCellCOPD-Myeloid-DC_Langerhans|COPD / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 GPR137B CLNK PLD4

3.50e-06158115671af1319eec34bf7bc9361ec9ef720c280ce97d1
ToppCellhealthy_donor-Lymphocytic-Plasma_cell-IgM_Plasmablast|healthy_donor / Disease condition, Lineage, Cell class and subclass

TSHR IGLV2-23 IGKV2D-30 IGHV4-4 IGKV2-30 IGKV2-28

4.65e-0616611562b7b580bec8d9467b0deaf97098065f72dbf2a4f
ToppCellBAL-Mild-Lymphocyte-B|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

AFF3 IGLV2-23 FCRL3 IGKV2D-30 IGKV2D-28 IGKV2-30

5.15e-061691156307571e57c3bfdf15f0fe1a8b36585e8e4f8a207
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Neuronal-interneuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

CLDN7 GRM1 ALMS1 FSHR SIGLEC1 CDH18

6.30e-06175115665571d775d26a40e979dbf290a8e4320c0d9fb3f
ToppCellCOPD-Lymphoid-B_Plasma|World / Disease state, Lineage and Cell class

IGLV2-23 IGKV2D-30 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

6.30e-061751156d73ee324479172501481b54967a0f3bd870fcf3a
ToppCell5'-GW_trimst-2-LargeIntestine-Hematopoietic-B_cells-Immature_B|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CYBB AFF3 IGKV2D-28 PLCG2 IGKV2-30 IGKV2-28

6.94e-0617811562e51c1596022b7047994ee13c18375bad19a54a5
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

7.16e-061791156837ed81f18257f444eaeadc4fac89deedd4e3061
ToppCellPBMC-Control-Lymphocyte-B-Plasmablast-Plasmablast|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

7.16e-061791156b6ee4f41d8fb5f047b7bdd8489dda0a89fc6d43f
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.1|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHR IGLV2-23 IGKV2D-30 PLCG2 IGKV2-30 IGKV2-28

7.40e-061801156e3877f6ef5f54ff689058b4c996ab1851822f871
ToppCellPCW_05-06-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

PLEKHB1 TIE1 ADGRF5 PLCG2 PREX1 HES5

7.40e-0618011565861b44acfb8fe92c281c8355bf19c059b3dcd64
ToppCellCOPD-Endothelial-VE_Capillary_A|World / Disease state, Lineage and Cell class

PALD1 TSHZ2 AFF3 TGFBR3 TIE1 ADGRF5

7.63e-06181115661608123959483ff60f07d8467996853c4371b6a
ToppCell5'-GW_trimst-1-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CASP10 TIE1 ADGRF5 PREX1 HES5 ALPG

7.63e-0618111567d7d1edeae4e0ebe40b324d1231cd26e27ba9d42
ToppCellImmune_cells-Dendritic_cells|Immune_cells / Lineage and Cell class

HPSE SH3BP4 GPR137B SMS KLRD1 PLD4

7.88e-06182115699c7d4f1e7cd745643ba64b59190113bcd4e348e
ToppCellcellseq-Immune-Lymphocytic_B-Lymphocytic_B-Plasma|cellseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30 IGKV2-28

8.13e-0618311565ab4aa0304b832f98fff89b6c24ad5b7dd014c11
ToppCellMild_COVID-19-B_cell|Mild_COVID-19 / Disease group,lineage and cell class (2021.01.30)

AFF3 IGLV2-23 FCRL3 PLCG2 IGKV2-30 PLD4

8.13e-061831156dea119e2988e954475f557f0bbe12556a83e81a4
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-thymocyte|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 NRCAM GRM1 CAPN8 MELTF GUCY2F

8.38e-0618411562cbed6462fea2622871bb7e49b0df3d984239281
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLB1 CRLF1 THSD7A TSHZ2 CLDN7 PLEKHB1

8.38e-061841156204d16c48f822c98dc4118ac97a4f99f7e1163c8
ToppCellCOPD-Myeloid-cDC1|World / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 SH3BP4 GPR137B CLNK

8.38e-06184115642d7ce104cd7bcb83fbbbd0e7d3267ad07edfa94
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 NRCAM GRM1 CAPN8 MELTF GUCY2F

8.38e-061841156ea7a7e2bac46d4d2c31a5d576b38a032b5335062
ToppCelldroplet-Lung-21m-Epithelial-airway_epithelial-club_cell|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PLB1 CRLF1 THSD7A TSHZ2 CLDN7 PLEKHB1

8.38e-0618411569365cdc52a2419e3f27e1c1c9310fa707d1e506b
ToppCellfacs-Thymus-Thymus_Epithelium-18m-Lymphocytic-proliferating_thymocyte;_DN_to_DP_transition,_dividing_(some_are_Cd8+/_Cd4+,_some_undergoing_VDJ_recombination)|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

HECW1 NRCAM GRM1 CAPN8 MELTF GUCY2F

8.38e-0618411562b19a8c5f823e00812908b23e66bb4e563278aff
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AFF3 IGLV2-23 FCRL3 IGKV2D-28 PLCG2 PLD4

8.38e-0618411563f8a359e40bebe58545f708682e5e5d1b70cf5cb
ToppCellBAL-Mild-Lymphocyte-B-B_cell-B_cell-|Mild / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

AFF3 IGLV2-23 FCRL3 IGKV2D-28 PLCG2 PLD4

8.38e-06184115664bede8db709fd32f40c03265b96f0b12155bb8a
ToppCellCOPD-Endothelial-VE_Capillary_A|COPD / Disease state, Lineage and Cell class

PALD1 TSHZ2 AFF3 TGFBR3 TIE1 ADGRF5

8.38e-0618411565f4f7775d488ececf086c71441defecbee9d8a9c
ToppCellBAL-Mild-Lymphocyte-B-B_cell|Mild / Location, Disease Group, Cell group, Cell class (2021.03.09)

AFF3 IGLV2-23 FCRL3 IGKV2D-28 PLCG2 PLD4

8.65e-061851156609080adb2cfb105bb7b8efb617553833299f371
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

8.65e-06185115608bc817908076734d66f2805cb954141f2cc5a18
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

8.65e-0618511561704a12153a9b107bf03ecccd1a036cf61334d7a
ToppCellIPF-Myeloid-cDC1|World / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 SH3BP4 GPR137B CLNK

8.92e-061861156962c2dada19185628ead77c32fcb07fa95114247
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial-blood_vessel_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLSTN3 THSD7A TIE1 ADGRF5 UTRN PREX1

9.19e-0618711560ef82111b9049cc7ee78d64d240e1f10ab14d6b6
ToppCellIPF-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 SH3BP4 GPR137B CLNK

9.48e-06188115647bb6caf84f70a1cda7d09803afdfd5182772e66
ToppCellCOPD-Endothelial-VE_Capillary_A|Endothelial / Disease state, Lineage and Cell class

PALD1 AFF3 EDIL3 TGFBR3 ADGRF5 PREX1

9.48e-0618811561aa0e35b1c28ac847886fece16c3ef7fc6fcdd51
ToppCell5'-Parenchyma_lung-Immune_Lymphocytic-Lymphocytic_B-plasma_cell-Plasma_cells-Plasma_cells_L.1.7.1.0|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGKV2-30 IGKV2-28

9.48e-0618811566844cebca177fdf38b21a40d606230a033717a3a
ToppCellIPF-Myeloid-cDC1|IPF / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 SH3BP4 GPR137B CLNK

9.48e-0618811562331a2bae1383820d598e93aa86c75b101069bac
ToppCellrenal_cortex_nuclei-Hypertensive_with+without-CKD-Epithelial-Collecting_tubule_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A NRCAM BMPR1B ADGRF5 PLCG2 CLNK

9.77e-061891156a9864873b19ab3e60acf11f288fa7275badc2e42
ToppCell10x5'-blood-Lymphocytic_B-Memory_B_cells|blood / Manually curated celltypes from each tissue

NRCAM AFF3 IGLV2-23 PLCG2 CLNK IGKV2-30

9.77e-0618911568aa65ffc396ccc5e86a6d38b99a2d51c34c9b6d2
ToppCellPCW_07-8.5-Endothelial-Endothelial_mature-endo_arterial_(9)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

CASP10 TIE1 ADGRF5 PLCG2 PREX1 HES5

1.01e-0519011561307688255a1250fa300edf2c41f1affe31dcc98
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)-D032|Children_(3_yrs) / Lineage, Cell type, age group and donor

PALD1 AFF3 SH3BP4 TGFBR3 TIE1 ADGRF5

1.01e-0519011560e9847d7f49b2236b8a191e1a7df37556351ba9e
ToppCellChildren_(3_yrs)-Endothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|Children_(3_yrs) / Lineage, Cell type, age group and donor

PALD1 AFF3 SH3BP4 TGFBR3 TIE1 ADGRF5

1.04e-051911156f229abf69a1217194f74b0502486907e07dba989
ToppCellCOPD-Myeloid-cDC2|World / Disease state, Lineage and Cell class

PALD1 AFF3 SH3BP4 MALT1 GPR137B PLD4

1.04e-0519111564e4887175200a57e1b041f2f131e3df774df3509
ToppCellCOPD-Myeloid-cDC1|Myeloid / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 SH3BP4 GPR137B CLNK

1.04e-0519111563480e6d27dd4291765bbbb2acdb6a2e4f02c8085
ToppCellCOPD-Myeloid-cDC1|COPD / Disease state, Lineage and Cell class

PALD1 AFF3 SLC2A1 SH3BP4 GPR137B CLNK

1.07e-051921156bd3d00b094d92463b06023361a71240851a542b8
ToppCellEndothelial-alveolar_capillary_endothelial_cell_(Cap2;_aerocyte)|World / Lineage, Cell type, age group and donor

PALD1 AFF3 TGFBR3 TIE1 ADGRF5 PREX1

1.07e-0519211561e156bab5ecf64627890d2de9b27603d9a01f28d
ToppCell5'-GW_trimst-1.5-SmallIntestine-Endothelial-blood_vessel_EC-Fetal_arterial_EC|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

THSD7A CASP10 TIE1 ADGRF5 PREX1 HES5

1.07e-0519211565a0615fdc217554ccd611504b16e5d97628e207d
ToppCellIPF-Myeloid-cDC2|IPF / Disease state, Lineage and Cell class

PALD1 AFF3 SH3BP4 MALT1 GPR137B PLD4

1.07e-051921156fe1de692fec48cba4a9bbc6eaa257260e8b4e800
ToppCellnucseq-Endothelial-Endothelial_Vascular-Endothelial_capillary|nucseq / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

PALD1 AFF3 TGFBR3 TIE1 ADGRF5 PREX1

1.10e-051931156f582e939e3e08a8a3f71deec78c33715be8faa51
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRICKLE1 EDIL3 JUP TIE1 ADGRF5 TRIM37

1.10e-0519311561b6317b740cad2439f08b9e9895426d861e7a161
ToppCelldroplet-Lung-3m-Endothelial-capillary_endothelial-capillary_endothelial_cell|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype

PRICKLE1 EDIL3 JUP TIE1 ADGRF5 TRIM37

1.10e-051931156f5861cfa4401b476229a7c61cd64abad79a4bbfc
ToppCellControl-NK_CD56bright|Control / Disease condition and Cell class

AFF3 SH3BP4 TIE1 PLCG2 CLNK KLRD1

1.10e-0519311568b1e7a226a6057e1097c1525984127b54e823876
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-28

1.10e-05193115634f6c13884fdf7f8a87f942fcb36a58cfac3f65d
ToppCellrenal_papilla_nuclei-Hypertensive_with+without-CKD-Endothelial-blood_vessel_endothelial_cell_of_kidney-arteriolar_vasa-recta_endothelial-Descending_Vasa_Recta_Endothelial_Cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

THSD7A AFF3 TIE1 ADGRF5 PLCG2 UTRN

1.13e-051941156a429d22c8c9d0fd3bfa9f877a6364cecad68db30
ToppCellcontrol-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CYBB AFF3 JUP FCRL3 PLCG2 PLD4

1.17e-051951156ff7956624b36df34e55295b295a71585accf07bd
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_plasma-B_plasma_IgA|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-28

1.17e-05195115613f4ee21568fd747608412d33559d10561dbb3c8
ToppCellBiopsy_Other_PF-Immune-Plasma_cells|Biopsy_Other_PF / Sample group, Lineage and Cell type

TSHR IGLV2-23 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-30

1.17e-051951156d0305c6a68c9e361507b04db94f86873085d49b3
ToppCellMid-temporal_gyrus_(MTG)-Neuronal|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 NRCAM AFF3 GRM5 TMEM59L CDH18

1.20e-051961156676c56b44ac29f7baecb62f49bb8597cc74c0a88
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 FCRL3 PLCG2 CLNK IGKV2-30 PLD4

1.20e-051961156e9fe5090452ffdde4bb81b62d57037d823281d00
ToppCellBronchial-NucSeq-Immune_Lymphocytic-B-B_plasma-B_plasma_IgG|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

NRCAM CASP10 TSHR IGKV2D-30 PLCG2 IGKV2-30

1.20e-051961156fd18a9ae8401121ae276adff1a85d5f938e2df91
ToppCellBronchial-10x5prime-Immune_Lymphocytic-B-B_cell-B_mature|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 FCRL3 PLCG2 CLNK IGKV2-30 PLD4

1.20e-051961156c2e17f3b2217f20bd7f28a1db4aa7d9a95c52a9c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

CLSTN3 THSD7A TIE1 ADGRF5 UTRN PREX1

1.20e-051961156629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCellmild-Lymphocytic-B_cells_1|Lymphocytic / Cohort 2 (Rhapsody WB + PBMC) with disease condition, lineage and cell classs

CYBB AFF3 JUP FCRL3 PLCG2 PLD4

1.20e-0519611561988088dd7e1ba947339fd1331beed482955e607
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 FCRL3 IGKV2D-30 IGKV2D-28 IGKV2-28 PLD4

1.24e-05197115676465bb2408c7c75f694e8f7cf1a606b796afc3a
ToppCellTracheal-10x3prime_v2-Immune_Myeloid-Dendritic_cell|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

CYBB PALD1 CLNK PREX1 MGAM2 PLD4

1.24e-0519711567e15ed71881105dee5c7ffc052063ecc8ac0b36e
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-28 PLD4

1.24e-0519711569fe1b757f76c2d43d39aa9ac500eaba98723985c
ToppCellSomatosensory_Cortex_(S1)-Neuronal|Somatosensory_Cortex_(S1) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 NRCAM AFF3 GRM5 TMEM59L CDH18

1.27e-051981156c01091ef18e096d792ea2a7a715764a5b215355f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial-blood_vessel_endothelial_cell_of_kidney|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 TIE1 PIK3C2A ADGRF5 UTRN PREX1

1.27e-051981156451003a21162eeae90739fdb502bb50b362d80c8
ToppCellprimary_auditory_cortex_(A1C)-Neuronal|primary_auditory_cortex_(A1C) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types

HECW1 NRCAM AFF3 GRM5 TMEM59L CDH18

1.27e-0519811566d18b45eda4014759e6dd282d78ffd28df8a6044
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor-epi-tip_intermediate|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CRLF1 CLDN7 PLEKHB1 SLC2A1 TMEM59L UTRN

1.27e-05198115684697f316d9195ebe838cf57f4dbdd9feea43bec
ToppCellTracheal-NucSeq-Immune_Lymphocytic-B-B_cell|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 IGLV2-23 FCRL3 PLCG2 CLNK PREX1

1.27e-051981156824461cf44098440ba8bc0df96735423ac65bda1
ToppCellwk_08-11-Epithelial-Distal_epithelial_progenitor|wk_08-11 / Celltypes from embryonic and fetal-stage human lung

CRLF1 CLDN7 PLEKHB1 SLC2A1 TMEM59L UTRN

1.27e-051981156eda85a592527992b51a00f288cff0c3239c47e6f
ToppCellrenal_cortex_nuclei-Adult_normal_reference-Endothelial|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

PALD1 TIE1 PIK3C2A ADGRF5 UTRN PREX1

1.27e-051981156440af8f90c7afa1c07000806bcf9110b70f489fb
ToppCellmedial-2-Endothelial-Capillary_Aerocyte|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.31e-051991156c5048b31649a0b7eddcd481b0458ed96508f5561
ToppCellBronchial-10x5prime-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 AFF3 EDIL3 TGFBR3 TIE1 ADGRF5

1.31e-0519911567ed541309808f15d65a9c4b26be2050e077539e6
ToppCelldistal-Endothelial-Capillary_Aerocyte-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.31e-0519911569021f4be004efd51bb3658e5bbff53589356b3df
ToppCellmedial-Endothelial-Capillary_Aerocyte|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.31e-05199115684e30c39c2f050aa64af167999824c1cba32ba05
ToppCellParenchymal-10x5prime-Immune_Lymphocytic-B-B_cell-B_naive|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations

AFF3 IGKV2D-30 IGKV2D-28 IGHV4-4 IGKV2-28 PLD4

1.31e-0519911568e02d3a066e79e0f2024a10738e0ea070513ef19
ToppCellParenchymal-NucSeq-Immune_Myeloid-Dendritic_cell-DC_activated|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

CH25H TG GPR137B PREX1 MGAM2 PLD4

1.31e-05199115682759af613ebfffe037afda55159bf6af812c3ac
ToppCellmedial-Endothelial-Capillary_Aerocyte-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.31e-051991156f1039d1ab498fc58f0feba545df05833c235db74
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal|GW23 / Sample Type, Dataset, Time_group, and Cell type.

PALD1 CH25H CASP10 LTBR PLCG2 SLC12A7

1.35e-0520011560eccf41edefc3b8b5d0316f57d5ba572949aec2b
ToppCellFetal_brain-organoid_Tanaka_cellReport-GW23-Mesenchymal-BMP_responsible_cell|GW23 / Sample Type, Dataset, Time_group, and Cell type.

PALD1 CH25H CASP10 LTBR PLCG2 SLC12A7

1.35e-05200115601d707c4f8ee0daac635b7260937b1baebc6fc23
ToppCellmedial-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 AFF3 TGFBR3 TIE1 ADGRF5

1.35e-052001156a8adf5902540f6bb15b72efbb9c389b59d67e001
ToppCellmedial-Endothelial-Capillary_Intermediate_1|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 AFF3 TGFBR3 TIE1 ADGRF5

1.35e-0520011563ef7b7728615710c691aed8977e2582f19692cf9
ToppCelldistal-2-Endothelial-Capillary_Intermediate_1|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.35e-0520011567a99f28670ffb8ece7873d8a9bcd2a3936d0255d
ToppCelldistal-Endothelial-Capillary_Intermediate_1-2|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.35e-05200115643bc48413b100a06f8edd9acd812296788fcbf5b
ToppCellmild-NK_CD56bright|World / Cohort 1 (10x PBMC) with disease condition, cell group and cell class

CLSTN3 SH3BP4 TIE1 CLNK UTRN KLRD1

1.35e-052001156a195bc6784346f706d4cd5b740adac1d950ce88a
ToppCelldistal-Endothelial-Capillary_Aerocyte|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.35e-052001156b91f8eb67752a77e1e08e462e50f1b5923695e1b
ToppCelldistal-1-Endothelial-Capillary_Aerocyte|1 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 EDIL3 ERVMER34-1 TGFBR3 TIE1 ADGRF5

1.35e-05200115659bacd738433cec6d05624a25fdfc087fb3ca3b5
ToppCelldistal-Endothelial-Capillary_Intermediate_1|distal / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 EDIL3 TGFBR3 TIE1 ADGRF5

1.35e-0520011564d6714d48738cdee7d535923f6dd2431e5304741
ToppCellBronchial-NucSeq-Endothelial-Endothelia_vascular-VE_alveolar_capillary_Car4_aerocyte|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations

PALD1 AFF3 EDIL3 TGFBR3 TIE1 PREX1

1.35e-052001156105c67e4f5eff036013d655c8e8ac577d32dae2e
ToppCellmedial-Endothelial-Capillary_Intermediate_1-2|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)

PALD1 TSHZ2 AFF3 TGFBR3 TIE1 ADGRF5

1.35e-052001156707148e01e961097819a05437a842b7d3bf72b0a
DrugAspartylglutamate

TSHR GRM1 GRM5 SLC2A1 BRAP TBCCD1 FSHR

5.57e-10401047CID000151403
Drugcorticosterone hemisuccinate

GRM1 GRM5 TRIM37

9.20e-0751043CID000159273
DrugTHV

CRLF1 TSHR TG TRIM37

1.88e-06201044CID011840983
DrugDelcorine; Up 200; 8.4uM; MCF7; HT_HG-U133A

HECW1 MCPH1 OGFR CASP10 GRM1 EDIL3 MELTF AOC3

3.20e-0619510483613_UP
Drugphenylarsine oxide

GRM1 GRM5 SLC2A1 TBCCD1 FSHR LTBR PLCG2 KLRD1 PLD4

4.85e-062751049CID000004778
DrugAC1NRAS8

APEH TG AOC3 CLNK

1.34e-05321044CID005288068
DrugWy-16,225

OGFR GRM1 GRM5

1.49e-05111043CID000040841
DrugSeldomycin-5

APEH HPSE

2.07e-0521042CID003043877
Drugxanthanoic acid

GRM1 GRM5

2.07e-0521042CID000065736
Drugphosphorus anion

APEH BRAP SMS TRIM37

2.69e-05381044CID009548888
Drugbeta-glycerophosphate

HPSE BRAP SIGLEC1 ALPI

3.31e-05401044CID000002526
DrugEucatropine hydrochloride [536-93-6]; Up 200; 12.2uM; PC3; HT_HG-U133A

PAPPA2 TSHZ2 AFF3 CASP10 TSHR TG KLRD1

3.64e-0519910473759_UP
Drugphenobarbital

GABRD UGT1A6 CH25H GRM1 GRM5 SLC2A1 AOC3 TRIM37 ALPI

4.10e-053601049CID000004763
Drugallantoate

APEH BRAP AOC3 SIGLEC1

4.85e-05441044CID000000203
Drugpheophytin

UGT1A6 HPSE ALMS1 PIK3C2A SIGLEC1 TRIM37 ALPI ALPG

4.86e-052841048CID000000250
Drugethylglutamate

APEH GRM1 GRM5

4.97e-05161043CID000014241
Drugstannite

SIGLEC1 TRIM37

6.18e-0531042CID006367227
Drugfenobam

GRM1 GRM5

6.18e-0531042CID000162834
DiseaseAutoimmune thyroiditis

TSHR TG FCRL3

1.80e-0741063C0920350
Diseasecardiomyopathy (is_implicated_in)

TSHR POMT1 JUP

4.19e-05191063DOID:0050700 (is_implicated_in)
Diseaseantiphospholipid syndrome

TSHR SH3BP4 CDH18

8.63e-05241063EFO_0002689
Disease1,5 anhydroglucitol measurement

PCDHA10 SI MGAM2

1.54e-04291063EFO_0008009
DiseaseIdiopathic generalized epilepsy

GABRD SLC2A1

1.90e-0461062C0270850
DiseaseGraves disease

PRICKLE1 TSHR TG FCRL3

2.12e-04811064EFO_0004237
Diseaserheumatoid arthritis

AFF3 GRM5 MELTF FCRL3 CLNK PREX1 SMTNL2 PLD4

2.69e-044621068EFO_0000685
Diseaserheumatoid arthritis, anti-citrullinated protein antibody seropositivity, rheumatoid factor seropositivity measurement

AFF3 FCRL3 CLNK SMTNL2 PLD4

3.79e-041701065EFO_0000685, EFO_0007791, EFO_0007837
Diseaseautoimmune disease

KCNH7 AFF3 TSHR TG CLNK

4.11e-041731065EFO_0005140
DiseaseGraves Disease

TSHR FCRL3

4.53e-0491062C0018213
Diseasemean corpuscular hemoglobin concentration

VIL1 CRISP2 CASP10 TSHR PLEKHB1 SLC2A1 BRAP ADGRF5 LTBR SLC12A7 PREX1 SMIM19

6.20e-04110510612EFO_0004528
Diseasejuvenile polyposis syndrome (implicated_via_orthology)

BMPR1A BMPR1B

9.72e-04131062DOID:0050787 (implicated_via_orthology)
DiseaseCongenital Hypothyroidism

TSHR TG

9.72e-04131062C0010308
Diseasetyrosine-protein kinase receptor Tie-1, soluble measurement

ADAMTS13 TIE1

9.72e-04131062EFO_0008312
Diseasecongenital hypothyroidism (implicated_via_orthology)

TSHR TG

1.13e-03141062DOID:0050328 (implicated_via_orthology)
Diseasenarcolepsy-cataplexy syndrome

PALD1 EDIL3 PREX1

1.27e-03591063MONDO_0016158
Diseasegestational age

NAALADL2 TGFBR3 MALRD1 UTRN

1.57e-031381064EFO_0005112
DiseaseEye Abnormalities

BMPR1A BMPR1B

1.68e-03171062C0015393
Diseasenon-Hodgkin lymphoma (is_implicated_in)

CASP10 MALT1

1.68e-03171062DOID:0060060 (is_implicated_in)
Diseaseurate measurement, bone density

PLB1 TSHZ2 UGT1A6 NAALADL2 TG BMPR1A CSNK2A1 UTRN

1.79e-036191068EFO_0003923, EFO_0004531
Diseasecognitive function measurement, self reported educational attainment

KCNH7 AFF3 ALMS1 CLNK PREX1 TRIM37

1.81e-033551066EFO_0004784, EFO_0008354
Diseasebipolar disorder, body mass index

TRIM42 TSHZ2 NAALADL2

2.24e-03721063EFO_0004340, MONDO_0004985
DiseaseJoubert syndrome 1

TRIM37 TCTN2

2.57e-03211062C4551568
DiseaseAttention Deficit Disorder

GRM1 GRM5

2.82e-03221062C0041671
DiseaseMinimal Brain Dysfunction

GRM1 GRM5

2.82e-03221062C1321905
Diseaseepilepsy (implicated_via_orthology)

KCNH7 NRCAM PRICKLE1 SLC12A7

2.88e-031631064DOID:1826 (implicated_via_orthology)
DiseaseEpilepsy, Benign Psychomotor, Childhood

GRM1 GRM5

3.08e-03231062C0393672
DiseaseEpilepsy, Lateral Temporal

GRM1 GRM5

3.08e-03231062C0393682
DiseaseUncinate Epilepsy

GRM1 GRM5

3.08e-03231062C0014558
DiseaseEpilepsy, Temporal Lobe

GRM1 GRM5

3.08e-03231062C0014556
DiseaseAttention deficit hyperactivity disorder

GRM1 GRM5

3.35e-03241062C1263846
Diseaseshort-term memory

DNAH12 GPR137B CDH18

3.36e-03831063EFO_0004335
Diseasecarotid plaque build

EPG5 TGFBR3 BMPR1B

3.48e-03841063EFO_0006501

Protein segments in the cluster

PeptideGeneStartEntry
GFVSSTWTYYLQTDN

TMEM59L

166

Q9UK28
HVSITNSILHSYDYW

AFF3

1161

P51826
TSNVFLQWAHSYADG

ERVPABLB-1

61

P60509
LGYVSDHWAQYVSHN

EPG5

651

Q9HCE0
TNHRVWDYAGDNYVH

BRAP

361

Q7Z569
WDYAGDNYVHRLVAS

BRAP

366

Q7Z569
ANWTAGLSVHYSQDS

CLSTN3

326

Q9BQT9
GLSVHYSQDSSLIYW

CLSTN3

331

Q9BQT9
DHFDAARSYGQYWTQ

ALMS1

386

Q8TCU4
ENHAPWSISDYFYQT

AGGF1

96

Q8N302
LEIYWETDYNHSGTI

CAPN8

611

A6NHC0
LLNVYTQWAESGYSS

DHX16

881

O60231
SWTQLYLITDYHENG

BMPR1B

271

O00238
NAVVGHYTQLVWYST

CRISP2

131

P16562
FHGQQVLYWESESSQ

ADAMTS13

1371

Q76LX8
STLLNYDYVWDTVFH

AOC3

466

Q16853
SWAYIQYESLDAAHA

RBM15

491

Q96T37
WNSTLQTLVASYEAY

PTPN23

651

Q9H3S7
NTYHVYHNTEDLWGE

PALD1

221

Q9ULE6
AFRDDDGHYSQTYWN

ANO7

831

Q6IWH7
AYAAWTTELGNLQSH

RELCH

706

Q9P260
SQSLVYSDGNTYLNW

IGKV2D-30

46

A0A075B6S6
WTYVSAVHTEGNYGE

GRM5

211

P41594
AYVEVWSSNGTENYS

MCPH1

11

Q8NEM0
EHYNVHNLYGWSQTR

MGAM2

1431

Q2M2H8
GTYWCHVYNDRDSQD

MALT1

286

Q9UDY8
AAAETYANISWEYEG

NRCAM

1076

Q92823
YANISWEYEGPEHVN

NRCAM

1081

Q92823
EEFYNQTWVHRYGES

SLC2A1

41

P11166
WDVSGQSSNDKYYTH

HIPK1

31

Q86Z02
EWIGEIYHSGSTNYN

IGHV4-4

66

A0A075B6R2
EEYFQHAWTYTNGID

KCNH7

701

Q9NS40
SYYSIGHSQDLVIHW

HECW1

86

Q76N89
WYPQAEVQNHSTSSY

ERVMER34-1

81

Q9H9K5
SQSLLHSNGYNYLDW

IGKV2D-28

46

P01615
SDVGSYNLVSWYQQH

IGLV2-23

46

P01705
FAAHGISSNWVSNYE

PIK3C2A

691

O00443
AQSTYADGIQDYWAD

FAM205A

186

Q6ZU69
VGLDYSNPWHSSYVQ

DNAH12

181

Q6ZR08
DIVYYWSESQEHIHG

GABRD

191

O14764
YWISSSHNTYLTGDQ

PLCG2

321

P16885
ADSGYNAWLSYHIVQ

PCDHGB3

596

Q9Y5G1
AVIWRGESHQYNADY

IGHV8-51-1

66

P0DTE2
GLEVESLQYYASQHW

NUDT13

251

Q86X67
WQQTYTYDSGIHSGA

JUP

16

P14923
DSVTWHHYYLNGRTA

HPSE

291

Q9Y251
AAWEVGSGQLHYSVY

PCDHA10

21

Q9Y5I2
GYNAWLSYELQSAAV

PCDHA10

601

Q9Y5I2
AGTYAHTVNRNWYSD

ALPI

176

P09923
LDTAQESVHVASYYW

PLD4

126

Q96BZ4
GYHGSTVWNVEEHRY

POMT1

501

Q9Y6A1
AGAYAHTVNRNWYSD

ALPG

176

P10696
ASGYNHDETQWYEDS

PRICKLE1

506

Q96MT3
VDHTQNTTDGWYLYA

MALRD1

1136

Q5VYJ5
GYLDQWATRAYSSHE

PAPPA2

1186

Q9BXP8
SQVALYTFGHRANEW

DCP1B

36

Q8IZD4
AYSNDGEHWTVYQDE

EDIL3

411

O43854
YESHVVEWGNQDDYQ

CSNK2A3

26

Q8NEV1
ATYENSNIAIYEGDW

GUCY2F

556

P51841
SWTQLYLITDYHENG

BMPR1A

301

P36894
YESHVVEWGNQDDYQ

CSNK2A1

26

P68400
SISHSLAQGDTYWYH

FCRL3

46

Q96P31
ATTQSDQDYHYLGDW

CDH18

756

Q13634
YNIYLTGWDESQANH

CYBB

476

P04839
RHAITAWYNETQFYD

GLIPR1L1

111

Q6UWM5
SQSLLHSNGYNYLDW

IGKV2-28

46

A0A075B6P5
SQSLVYSDGNTYLNW

IGKV2-30

46

P06310
YVSFRHVEEGSWYIQ

CASP10

446

Q92851
WHQASEGLTDYSFYR

IZUMO1

186

Q8IYV9
RSYHVYPEQGNWEAS

DHRS7C

226

A6NNS2
KSQYHNYAIDWQTGA

FSHR

426

P23945
RYNWTYVSAVHTEGN

GRM1

221

Q13255
RWYGQDNTCEEYHTV

CRLF1

176

O75462
ASGVFLENLWSTYAH

SLC12A7

371

Q9Y666
TTYHWQELSYTEGLS

METTL17

141

Q9H7H0
VNIWLSVEDHSGYNF

CH25H

206

O95992
TALHWSAYYNNPEHV

INVS

151

Q9Y283
NWTDNYDLLEDNHSY

OGFR

116

Q9NZT2
QGDSMEGSYEHWYQQ

IGLV3-32

41

A0A0A0MS00
VHSFDYDWYNVSDQA

GPR137B

266

O60478
IFDGNVAHISTWLYQ

UTRN

1656

P46939
TWQDHGYLATYTNKN

SMS

41

P52788
YTHVNGWANGAYSLV

SOX3

261

P41225
HWYITQLEAAQTSYI

TRIM37

416

O94972
LYTYWSAGADSQSVQ

TRIM42

571

Q8IWZ5
ATQTYEAWLGHEYLH

MELTF

336

P08582
YDFLLTWSHQIGDSY

SH3BP4

896

Q9P0V3
HYDYNVTDWSTCQLS

THSD7A

1221

Q9UPZ6
ADYHSNGYTVTNGWK

PREX1

346

Q8TCU6
YATYERGNTQHVWIN

SI

441

P14410
GISSFSYWHQYTQRE

PLB1

1301

Q6P1J6
SYWHQYTQREDFAVV

PLB1

1306

Q6P1J6
QDYSEGYSWCLQEAV

HES5

86

Q5TA89
EEYWSRYVLHIQGSQ

SLC6A7

191

Q99884
TTQYGGQYRTVHTEW

APEH

36

P13798
VSNYDEVYWNTSAGI

ADGRF5

496

Q8IZF2
ACSWYGHQIVTDFYN

CLDN7

136

O95471
HNEWYIGEYSRQAVE

CLNK

306

Q7Z7G1
SGHTSVYWYQQALGL

TRBV5-8

46

A0A5A2
SSLSYDIHYWIGQDS

VIL1

56

P09327
SVVDYNAYAGVWSQD

YTHDF3

481

Q7Z739
WEDLTQQYYSLVHGD

TTLL8

301

A6PVC2
NQLYFTYSVHWEESD

TM9SF4

246

Q92544
WLDGTLGYYHDETAQ

PLEKHB1

46

Q9UF11
NGSYFYTLDWHEAQD

TIE1

161

P35590
YTVHEAWNEATNVYL

SMIM19

16

Q96E16
LGYQHVDLQNFSSSW

SMTNL2

366

Q2TAL5
SSHATLYWYQQALGQ

TRBV7-7

46

A0A0K0K1E9
TTHPAQLTYTWYQDG

SIGLEC1

1111

Q9BZZ2
HSTISGTDYIHWYRQ

TRAV26-2

41

A0A0B4J265
SAYLEDHSYNVEQIW

TTLL6

291

Q8N841
TAVYANILSDSYWSG

TSHZ2

126

Q9NRE2
ATCAENSYNEHWNYL

LTBR

81

P36941
TSESWTNQDDIFYAY

nan

26

Q6ZS52
WNDYSHQAFVYDHLS

TBCCD1

166

Q9NVR7
KDIDEQTQEHWYTSY

WDR24

666

Q96S15
QTQEHWYTSYIDLLQ

WDR24

671

Q96S15
AAHDLTWYQYHSLDV

UGT1A6

476

P19224
VEAAATWYYSLEHST

TG

2556

P01266
WTQYYQGELHSQCVA

TCTN2

656

Q96GX1
WYIYSHTGETAGRQQ

TGFBR3

806

Q03167
YTHSEYYNHAIDWQT

TSHR

476

P16473
GNHEYYTSDVSNWFA

TMPPE

276

Q6ZT21
SQQFYWIGLSYSEEH

KLRD1

111

Q13241
HSYNGQEWASSTAII

NAALADL2

456

Q58DX5