Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	GTPase binding	DOCK2 MYO5A DENND1A CYRIB BICD1 RBSN XPO5 NXT1 LAMTOR1	1.48e-04	360	108	9	GO:0051020
GeneOntologyMolecularFunction	BAT3 complex binding	AMFR USP13	1.73e-04	4	108	2	GO:1904288
GeneOntologyMolecularFunction	pyruvate dehydrogenase (acetyl-transferring) kinase activity	PDK2 PDK3	2.87e-04	5	108	2	GO:0004740
GeneOntologyMolecularFunction	small GTPase binding	DOCK2 MYO5A DENND1A CYRIB BICD1 RBSN XPO5 NXT1	3.57e-04	321	108	8	GO:0031267
GeneOntologyMolecularFunction	cytoskeletal motor activity	MYO1G DNAH10 MYO5A MYO5C DNAH17	4.54e-04	118	108	5	GO:0003774
GeneOntologyMolecularFunction	ATP-dependent activity	ATP5PB MYO1G DNAH10 MYO5A CHD8 CHD7 MORC2 MYO5C ATAD3C DNAH17 TAP2	4.93e-04	614	108	11	GO:0140657
GeneOntologyBiologicalProcess	chemosensory behavior	CHD7 GRIN1 UBR3 MRGPRX4	1.73e-05	31	104	4	GO:0007635
GeneOntologyCellularComponent	TEAD-YAP complex	TEAD2 TEAD1	7.62e-05	3	106	2	GO:0140552
GeneOntologyCellularComponent	motile cilium	CATSPERE DNAH10 PRAMEF22 PRAMEF18 RSPH3 GRK3 DNAH17 RSPH9 BRWD1	8.20e-05	355	106	9	GO:0031514
GeneOntologyCellularComponent	radial spoke 1	RSPH3 RSPH9	1.52e-04	4	106	2	GO:0120333
GeneOntologyCellularComponent	radial spoke 3	RSPH3 RSPH9	1.52e-04	4	106	2	GO:0120335
GeneOntologyCellularComponent	radial spoke head 1	RSPH3 RSPH9	1.52e-04	4	106	2	GO:0120336
GeneOntologyCellularComponent	radial spoke head 3	RSPH3 RSPH9	1.52e-04	4	106	2	GO:0120338
GeneOntologyCellularComponent	cell leading edge	MYO1G MYO5A GRIN1 FAT1 SLC9A5 MTM1 ARHGEF4 USH2A DAGLA EXOC4	2.29e-04	500	106	10	GO:0031252
GeneOntologyCellularComponent	radial spoke head	RSPH3 RSPH9	2.52e-04	5	106	2	GO:0001535
GeneOntologyCellularComponent	filopodium	MYO1G MYO5A FAT1 NPTXR MTM1	4.10e-04	123	106	5	GO:0030175
GeneOntologyCellularComponent	actin-based cell projection	MYO1G MYO5A FAT1 NPTXR MTM1 USH2A EXOC4	5.42e-04	278	106	7	GO:0098858
GeneOntologyCellularComponent	axon	AMFR MYO5A SYNPO GRIN1 ITPR2 ADRA2C GRK3 NPTXR MRGPRX4 PLEC USH2A DAGLA EXOC4	5.73e-04	891	106	13	GO:0030424
GeneOntologyCellularComponent	cilium	CATSPERE DNAH10 MYO5A PRAMEF22 PRAMEF18 CYRIB TTC8 RSPH3 GRK3 DNAH17 USH2A RSPH9 BRWD1	6.16e-04	898	106	13	GO:0005929
GeneOntologyCellularComponent	leading edge membrane	MYO1G GRIN1 SLC9A5 ARHGEF4 USH2A DAGLA	7.09e-04	210	106	6	GO:0031256
GeneOntologyCellularComponent	neuron projection membrane	GRIN1 SLC9A5 USH2A DAGLA	8.06e-04	82	106	4	GO:0032589
GeneOntologyCellularComponent	chromatin	TEAD2 GSX1 RRP1B PRAMEF22 CHD8 CHD7 TSPY26P TEAD1 TEAD3 PRAMEF18 MORC2 TRRAP HOXA9 SF3B1 HOXD9 FANCI ELF3	1.22e-03	1480	106	17	GO:0000785
GeneOntologyCellularComponent	somatodendritic compartment	AMFR FRMPD4 MYO5A SYNPO GRIN1 DENND1A ADRA2C SLC9A5 GRK3 NPTXR MRGPRX4 PLEC USH2A DAGLA EXOC4	1.33e-03	1228	106	15	GO:0036477
GeneOntologyCellularComponent	dendrite	AMFR FRMPD4 MYO5A SYNPO GRIN1 DENND1A SLC9A5 GRK3 NPTXR PLEC DAGLA EXOC4	1.35e-03	858	106	12	GO:0030425
GeneOntologyCellularComponent	9+2 motile cilium	CATSPERE DNAH10 RSPH3 GRK3 DNAH17 RSPH9	1.35e-03	238	106	6	GO:0097729
GeneOntologyCellularComponent	dendritic tree	AMFR FRMPD4 MYO5A SYNPO GRIN1 DENND1A SLC9A5 GRK3 NPTXR PLEC DAGLA EXOC4	1.38e-03	860	106	12	GO:0097447
GeneOntologyCellularComponent	dendritic spine	FRMPD4 SYNPO GRIN1 SLC9A5 GRK3 DAGLA	1.47e-03	242	106	6	GO:0043197
GeneOntologyCellularComponent	I band	SYNPO GRK3 BMP10 MTM1 PLEC	1.58e-03	166	106	5	GO:0031674
GeneOntologyCellularComponent	neuron spine	FRMPD4 SYNPO GRIN1 SLC9A5 GRK3 DAGLA	1.63e-03	247	106	6	GO:0044309
GeneOntologyCellularComponent	radial spoke	RSPH3 RSPH9	2.56e-03	15	106	2	GO:0001534
GeneOntologyCellularComponent	dendrite membrane	GRIN1 SLC9A5 DAGLA	2.89e-03	56	106	3	GO:0032590
Domain	TEA_1	TEAD2 TEAD1 TEAD3	7.28e-07	4	107	3	PS00554
Domain	TEA_2	TEAD2 TEAD1 TEAD3	7.28e-07	4	107	3	PS51088
Domain	TEA	TEAD2 TEAD1 TEAD3	7.28e-07	4	107	3	PF01285
Domain	TEA/ATTS_dom	TEAD2 TEAD1 TEAD3	7.28e-07	4	107	3	IPR000818
Domain	TEF_metazoa	TEAD2 TEAD1 TEAD3	7.28e-07	4	107	3	IPR016361
Domain	TEA	TEAD2 TEAD1 TEAD3	7.28e-07	4	107	3	SM00426
Domain	HATPase_c	PDK2 PDK3 MORC2	1.40e-04	18	107	3	SM00387
Domain	HATPase_c	PDK2 PDK3 MORC2	1.66e-04	19	107	3	PF02518
Domain	Hox9_activation_N	HOXA9 HOXD9	1.94e-04	4	107	2	IPR006711
Domain	HXA9/HXB9/HXC9	HOXA9 HOXD9	1.94e-04	4	107	2	IPR017112
Domain	Hox9_act	HOXA9 HOXD9	1.94e-04	4	107	2	PF04617
Domain	-	PDK2 PDK3 MORC2	1.94e-04	20	107	3	3.30.565.10
Domain	HATPase_C	PDK2 PDK3 MORC2	2.26e-04	21	107	3	IPR003594
Domain	BCDHK_Adom3	PDK2 PDK3	3.22e-04	5	107	2	PF10436
Domain	Myosin_S1_N	MYO5A MYO5C	3.22e-04	5	107	2	IPR008989
Domain	His_kinase_dom	PDK2 PDK3	3.22e-04	5	107	2	IPR005467
Domain	HIS_KIN	PDK2 PDK3	3.22e-04	5	107	2	PS50109
Domain	BCDHK/PDK_N	PDK2 PDK3	3.22e-04	5	107	2	IPR018955
Domain	-	PDK2 PDK3	3.22e-04	5	107	2	1.20.140.20
Domain	BRK	CHD8 CHD7	4.80e-04	6	107	2	SM00592
Domain	Dilute_dom	MYO5A MYO5C	4.80e-04	6	107	2	IPR002710
Domain	BRK_domain	CHD8 CHD7	4.80e-04	6	107	2	IPR006576
Domain	DIL	MYO5A MYO5C	4.80e-04	6	107	2	PF01843
Domain	DILUTE	MYO5A MYO5C	4.80e-04	6	107	2	PS51126
Domain	DIL	MYO5A MYO5C	4.80e-04	6	107	2	SM01132
Domain	BRK	CHD8 CHD7	4.80e-04	6	107	2	PF07533
Domain	Myosin_head_motor_dom	MYO1G MYO5A MYO5C	1.33e-03	38	107	3	IPR001609
Domain	MYOSIN_MOTOR	MYO1G MYO5A MYO5C	1.33e-03	38	107	3	PS51456
Domain	LAM_G_DOMAIN	FAT1 FAT2 USH2A	1.33e-03	38	107	3	PS50025
Domain	Myosin_head	MYO1G MYO5A MYO5C	1.33e-03	38	107	3	PF00063
Domain	MYSc	MYO1G MYO5A MYO5C	1.33e-03	38	107	3	SM00242
Domain	Laminin_G_2	FAT1 FAT2 USH2A	1.55e-03	40	107	3	PF02210
Domain	LamG	FAT1 FAT2 USH2A	2.04e-03	44	107	3	SM00282
Domain	-	FAT1 FAT2 NPTXR USH2A	2.17e-03	95	107	4	2.60.120.200
Domain	ARM-type_fold	DOCK2 TRRAP ITPR2 SF3B1 XPO5 PI4KA ASPM	3.38e-03	339	107	7	IPR016024
Domain	-	TRRAP PI4KA	3.70e-03	16	107	2	1.10.1070.11
Domain	PI3Kc	TRRAP PI4KA	3.70e-03	16	107	2	SM00146
Domain	Interferon	IFNA7 IFNA16	4.18e-03	17	107	2	PF00143
Domain	INTERFERON_A_B_D	IFNA7 IFNA16	4.18e-03	17	107	2	PS00252
Domain	Interferon_alpha/beta/delta	IFNA7 IFNA16	4.18e-03	17	107	2	IPR000471
Domain	IFabd	IFNA7 IFNA16	4.18e-03	17	107	2	SM00076
Domain	Laminin_G	FAT1 FAT2 USH2A	4.49e-03	58	107	3	IPR001791
Domain	PI3_PI4_kinase	TRRAP PI4KA	4.69e-03	18	107	2	PF00454
Domain	PI3_4_KINASE_1	TRRAP PI4KA	4.69e-03	18	107	2	PS00915
Domain	PI3_4_KINASE_2	TRRAP PI4KA	4.69e-03	18	107	2	PS00916
Domain	PI3/4_kinase_cat_dom	TRRAP PI4KA	4.69e-03	18	107	2	IPR000403
Domain	PI3_4_KINASE_3	TRRAP PI4KA	4.69e-03	18	107	2	PS50290
Domain	Myosin-like_IQ_dom	MYO5C ASPM	5.22e-03	19	107	2	IPR027401
Domain	-	MYO5C ASPM	5.22e-03	19	107	2	4.10.270.10
Domain	PRAME_family	PRAMEF22 PRAMEF18	5.22e-03	19	107	2	IPR026271
Pathway	REACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION	TEAD2 TEAD1 TEAD3	4.18e-06	6	85	3	MM15544
Pathway	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	TEAD2 TEAD1 TEAD3	1.16e-05	8	85	3	MM14816
Pathway	REACTOME_RUNX3_REGULATES_YAP1_MEDIATED_TRANSCRIPTION	TEAD2 TEAD1 TEAD3	1.16e-05	8	85	3	M27823
Pathway	REACTOME_YAP1_AND_WWTR1_TAZ_STIMULATED_GENE_EXPRESSION	TEAD2 TEAD1 TEAD3	9.14e-05	15	85	3	M603
Pathway	WP_MIR5093P_ALTERATION_OF_YAP1ECM_AXIS	TEAD2 TEAD1 TEAD3	1.62e-04	18	85	3	M39421
Pathway	WP_TRANSCRIPTION_COFACTORS_SKI_AND_SKIL_PROTEIN_PARTNERS	TEAD2 TEAD1 TEAD3	1.62e-04	18	85	3	M39825
Pathway	WP_HIPPOYAP_SIGNALING	TEAD2 TEAD1 TEAD3	3.00e-04	22	85	3	M39821
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	ATP5PB AMFR CATSPERE MYO5A PDK3 PRAMEF22 TENT5C CHD7 GRIN1 TEAD3 PRAMEF18 TRRAP DPH6 RBSN CRLS1 ATAD3C FANCI DNAH17 ASPM ARHGEF4	1.45e-09	1242	108	20	30973865
Pubmed	Human transcription factor protein interaction networks.	ATP5PB TEAD2 RPL34 DNAH10 MYO5A RRP1B RPS11 NUP98 WDR83 CHD8 CHD7 TEAD1 TEAD3 MORC2 TRRAP MYO5C MRPS10 FAT1 TIMM10B ELF3 EXOC4	2.70e-09	1429	108	21	35140242
Pubmed	Localization of human transcription factor TEF-4 and TEF-5 (TEAD2, TEAD3) genes to chromosomes 19q13.3 and 6p21.2 using fluorescence in situ hybridization and radiation hybrid analysis.	TEAD2 TEAD1 TEAD3	1.16e-07	4	108	3	9889009
Pubmed	The TEA domain: a novel, highly conserved DNA-binding motif.	TEAD2 TEAD1 TEAD3	1.16e-07	4	108	3	2070413
Pubmed	A novel family of developmentally regulated mammalian transcription factors containing the TEA/ATTS DNA binding domain.	TEAD2 TEAD1 TEAD3	1.16e-07	4	108	3	8702974
Pubmed	Tead transcription factors differentially regulate cortical development.	TEAD2 TEAD1 TEAD3	1.16e-07	4	108	3	32170161
Pubmed	Comparative expression analysis of TEADs and their splice variants in mouse embryonic stem cells.	TEAD2 TEAD1 TEAD3	1.16e-07	4	108	3	36516960
Pubmed	Transcription factor mTEAD-2 is selectively expressed at the beginning of zygotic gene expression in the mouse.	TEAD2 TEAD1 TEAD3	1.16e-07	4	108	3	9169843
Pubmed	Functional proteomics establishes the interaction of SIRT7 with chromatin remodeling complexes and expands its role in regulation of RNA polymerase I transcription.	ACACA MYO5A RRP1B NUP98 CHD8 CHD7 TRRAP SF3B1 XPO5 FANCI PLEC CLUH PHIP	1.29e-07	653	108	13	22586326
Pubmed	TEAD mediates YAP-dependent gene induction and growth control.	TEAD2 TEAD1 TEAD3	2.90e-07	5	108	3	18579750
Pubmed	TONDU (TDU), a novel human protein related to the product of vestigial (vg) gene of Drosophila melanogaster interacts with vertebrate TEF factors and substitutes for Vg function in wing formation.	TEAD2 TEAD1 TEAD3	2.90e-07	5	108	3	10518497
Pubmed	Differential expression of the TEF family of transcription factors in the murine placenta and during differentiation of primary human trophoblasts in vitro.	TEAD2 TEAD1 TEAD3	2.90e-07	5	108	3	9671946
Pubmed	Members of the TEAD family of transcription factors regulate the expression of Myf5 in ventral somitic compartments.	TEAD2 TEAD1 TEAD3	2.90e-07	5	108	3	21527258
Pubmed	TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition.	TEAD2 TEAD1 TEAD3	2.90e-07	5	108	3	19324877
Pubmed	Genetic and pharmacological disruption of the TEAD-YAP complex suppresses the oncogenic activity of YAP.	TEAD2 TEAD1 TEAD3	2.90e-07	5	108	3	22677547
Pubmed	Cullin 1 (CUL1) Promotes Primary Ciliogenesis through the Induction of Ubiquitin-Proteasome-Dependent Dvl2 Degradation.	ATP5PB ACACA BICD1 HOXA9 FAT2 FANCI PLEC	5.11e-07	152	108	7	34299191
Pubmed	Hippo Component TAZ Functions as a Co-repressor and Negatively Regulates ΔNp63 Transcription through TEA Domain (TEAD) Transcription Factor.	TEAD2 TEAD1 TEAD3	5.78e-07	6	108	3	25995450
Pubmed	TEAD/TEF transcription factors utilize the activation domain of YAP65, a Src/Yes-associated protein localized in the cytoplasm.	TEAD2 TEAD1 TEAD3	5.78e-07	6	108	3	11358867
Pubmed	Identification of minimal enhancer elements sufficient for Pax3 expression in neural crest and implication of Tead2 as a regulator of Pax3.	TEAD2 TEAD1 TEAD3	1.01e-06	7	108	3	14736747
Pubmed	Tead proteins activate the Foxa2 enhancer in the node in cooperation with a second factor.	TEAD2 TEAD1 TEAD3	1.01e-06	7	108	3	16207754
Pubmed	Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS.	DOCK2 MYO1G RRP1B RPS11 NUP98 SF3B1 NXT1 PLEC PHIP	1.23e-06	340	108	9	29478914
Pubmed	Neuron-specific protein network mapping of autism risk genes identifies shared biological mechanisms and disease-relevant pathologies.	ATP5PB RPL34 FRMPD4 ACACA MYO5A PDK2 PDK3 SYNPO GRIN1 RBSN SF3B1 ATAD3C PI4KA UBR3 PLEC	2.48e-06	1139	108	15	36417873
Pubmed	Mechanosignalling via integrins directs fate decisions of pancreatic progenitors.	TEAD2 TEAD1 TEAD3 PPY	2.96e-06	32	108	4	30487608
Pubmed	Transcription factor protein interactomes reveal genetic determinants in heart disease.	ATP5PB ACACA RRP1B RPS11 NUP98 CHD8 CHD7 SF3B1 TMEM63A	5.75e-06	411	108	9	35182466
Pubmed	Expression pattern of transcriptional enhanced associate domain family member 1 (Tead1) in developing mouse molar tooth.	TEAD2 TEAD1 TEAD3	8.14e-06	13	108	3	33984529
Pubmed	Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses.	DOCK2 IFNA7 IFNA16	8.14e-06	13	108	3	22431588
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	TEAD2 ACACA POMGNT1 CHD8 TRRAP DENND1A KCNH3 ITPR2 FAT1 FANCI PI4KA TMEM268 ARHGEF4 PLEC	8.56e-06	1105	108	14	35748872
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	ATP5PB RPL34 MYO5A RPS11 NCKIPSD SYNPO GRIN1 CYRIB ITPR2 SF3B1 ATAD3C PI4KA ARHGEF4 PLEC DAGLA EXOC4	8.90e-06	1431	108	16	37142655
Pubmed	TEAD3 inhibits the proliferation and metastasis of prostate cancer via suppressing ADRBK2.	TEAD3 GRK3	9.55e-06	2	108	2	36907139
Pubmed	Fusion of the nucleoporin gene NUP98 to HOXA9 by the chromosome translocation t(7;11)(p15;p15) in human myeloid leukaemia.	NUP98 HOXA9	9.55e-06	2	108	2	8563753
Pubmed	The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9.	NUP98 HOXA9	9.55e-06	2	108	2	8563754
Pubmed	CHD8 interacts with CHD7, a protein which is mutated in CHARGE syndrome.	CHD8 CHD7	9.55e-06	2	108	2	20453063
Pubmed	The oncogene Nup98-HOXA9 induces gene transcription in myeloid cells.	NUP98 HOXA9	9.55e-06	2	108	2	14561764
Pubmed	Loss of function of the homeobox gene Hoxa-9 perturbs early T-cell development and induces apoptosis in primitive thymocytes.	MYO5A HOXA9	9.55e-06	2	108	2	9657735
Pubmed	The molecular pathogenesis of the NUP98-HOXA9 fusion protein in acute myeloid leukemia.	NUP98 HOXA9	9.55e-06	2	108	2	28630438
Pubmed	Overexpression of PDK2 and PDK3 reflects poor prognosis in acute myeloid leukemia.	PDK2 PDK3	9.55e-06	2	108	2	30578412
Pubmed	Colorectal carcinomas with CpG island methylator phenotype 1 frequently contain mutations in chromatin regulators.	CHD8 CHD7	9.55e-06	2	108	2	24211491
Pubmed	Phase separation drives aberrant chromatin looping and cancer development.	NUP98 HOXA9	9.55e-06	2	108	2	34163069
Pubmed	Human NUP98-HOXA9 promotes hyperplastic growth of hematopoietic tissues in Drosophila.	NUP98 HOXA9	9.55e-06	2	108	2	27838340
Pubmed	Identification of the Isoform-specific Interactions between the Tail and the Head of Class V Myosin.	MYO5A MYO5C	9.55e-06	2	108	2	26912658
Pubmed	Specific and redundant functions of the paralogous Hoxa-9 and Hoxd-9 genes in forelimb and axial skeleton patterning.	HOXA9 HOXD9	9.55e-06	2	108	2	8625797
Pubmed	Marked differences between two isoforms of human pyruvate dehydrogenase kinase.	PDK2 PDK3	9.55e-06	2	108	2	10748134
Pubmed	Human myosin-Vc is a novel class V myosin expressed in epithelial cells.	MYO5A MYO5C	9.55e-06	2	108	2	11870218
Pubmed	Dissection of the transformation of primary human hematopoietic cells by the oncogene NUP98-HOXA9.	NUP98 HOXA9	9.55e-06	2	108	2	19696924
Pubmed	A case of acute myeloid leukemia with t(7;11)(p15;p15) mimicking myeloid crisis of chronic myelogenous leukemia.	NUP98 HOXA9	9.55e-06	2	108	2	12138901
Pubmed	TEAD1 and TEAD3 Play Redundant Roles in the Regulation of Human Epidermal Proliferation.	TEAD1 TEAD3	9.55e-06	2	108	2	32142794
Pubmed	A protein-interaction network of interferon-stimulated genes extends the innate immune system landscape.	ATP5PB AMFR RPL34 RRP1B SHMT2 SYNPO DENND1A CYRIB ITPR2 MRPS10 SF3B1 XPO5 FANCI LAMTOR1 TAP2 EXOC4	9.62e-06	1440	108	16	30833792
Pubmed	Mapping the NPHP-JBTS-MKS protein network reveals ciliopathy disease genes and pathways.	AMFR MYO5A PRAMEF22 PRAMEF18 XPO5 PI4KA GPC4 PLEC EXOC4 TMEM63A	1.09e-05	564	108	10	21565611
Pubmed	Comprehensive interactome profiling of the human Hsp70 network highlights functional differentiation of J domains.	SELENOT ATP5PB RPL34 MYO5A RRP1B PDK3 SHMT2 ITPR2 MRPS10 SF3B1 TRABD PI4KA ASPM LAMTOR1 CLUH EXOC4	1.43e-05	1487	108	16	33957083
Pubmed	Identifying biological pathways that underlie primordial short stature using network analysis.	ATP5PB MYO5A RRP1B RPS11 NUP98 SHMT2 TRRAP MYO5C ITPR2 SF3B1 PI4KA PLEC PHIP	1.80e-05	1024	108	13	24711643
Pubmed	Transcriptome analysis of mouse stem cells and early embryos.	ACACA PRAMEF22 CHD7 PRAMEF18 FANCI GPC4 ASPM PLEC	1.85e-05	363	108	8	14691545
Pubmed	Proteomic profiling of VCP substrates links VCP to K6-linked ubiquitylation and c-Myc function.	RPL34 ACACA MYO5A RPS11 SHMT2 CHD8 CHD7 TRRAP SF3B1 FANCI PI4KA ASPM PLEC PHIP EXOC4	1.93e-05	1353	108	15	29467282
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	RRP1B CHD8 SYNPO CHD7 TEAD1 MORC2 TRRAP FANCI PHIP BRWD1	2.07e-05	608	108	10	36089195
Pubmed	TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation.	RRP1B CHD8 CHD7 XPO5 PHIP	2.38e-05	109	108	5	33554859
Pubmed	Organogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitors.	TEAD2 TEAD1 TEAD3	2.72e-05	19	108	3	20596238
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	RRP1B NUP98 CHD8 MORC2 RBSN SF3B1 FANCI MTM1 EXOC4	2.84e-05	503	108	9	16964243
Pubmed	RNA export factor RAE1 contributes to NUP98-HOXA9-mediated leukemogenesis.	NUP98 HOXA9	2.86e-05	3	108	2	21467841
Pubmed	Oligodendrocyte precursor survival and differentiation requires chromatin remodeling by Chd7 and Chd8.	CHD8 CHD7	2.86e-05	3	108	2	30108144
Pubmed	The chromosome translocation t(7;11)(p15;p15) in acute myeloid leukemia results in fusion of the NUP98 gene with a HOXA cluster gene, HOXA13, but not HOXA9.	NUP98 HOXA9	2.86e-05	3	108	2	12112533
Pubmed	MLL is essential for NUP98-HOXA9-induced leukemia.	NUP98 HOXA9	2.86e-05	3	108	2	28210005
Pubmed	Chronic corticosterone exposure alters postsynaptic protein levels of PSD-95, NR1, and synaptopodin in the mouse brain.	SYNPO GRIN1	2.86e-05	3	108	2	21190219
Pubmed	Fanconi anemia FANCD2 and FANCI proteins regulate the nuclear dynamics of splicing factors.	SF3B1 FANCI	2.86e-05	3	108	2	29030393
Pubmed	Comparative genomics and diversifying selection of the clustered vertebrate protocadherin genes.	FAT1 FAT2	2.86e-05	3	108	2	15744052
Pubmed	Enforced expression of NUP98-HOXA9 in human CD34(+) cells enhances stem cell proliferation.	NUP98 HOXA9	2.86e-05	3	108	2	17178874
Pubmed	Chromatin-prebound Crm1 recruits Nup98-HoxA9 fusion to induce aberrant expression of Hox cluster genes.	NUP98 HOXA9	2.86e-05	3	108	2	26740045
Pubmed	Functional interaction between the p160 coactivator proteins and the transcriptional enhancer factor family of transcription factors.	TEAD2 TEAD1	2.86e-05	3	108	2	10934189
Pubmed	Structural insights into the globular tails of the human type v myosins Myo5a, Myo5b, And Myo5c.	MYO5A MYO5C	2.86e-05	3	108	2	24339992
Pubmed	Cell competition in mouse NIH3T3 embryonic fibroblasts is controlled by the activity of Tead family proteins and Myc.	TEAD2 TEAD1	2.86e-05	3	108	2	25588835
Pubmed	A phosphoinositide conversion mechanism for exit from endosomes.	MTM1 EXOC4	2.86e-05	3	108	2	26760201
Pubmed	A novel family of TEA domain-containing transcription factors with distinct spatiotemporal expression patterns.	TEAD1 TEAD3	2.86e-05	3	108	2	8920920
Pubmed	The ATP-dependent chromatin remodeling enzymes CHD6, CHD7, and CHD8 exhibit distinct nucleosome binding and remodeling activities.	CHD8 CHD7	2.86e-05	3	108	2	28533432
Pubmed	Structural insights into functional overlapping and differentiation among myosin V motors.	MYO5A MYO5C	2.86e-05	3	108	2	24097982
Pubmed	Autism-linked CHD gene expression patterns during development predict multi-organ disease phenotypes.	CHD8 CHD7	2.86e-05	3	108	2	30277262
Pubmed	The Retinoblastoma Tumor Suppressor Is Required for the NUP98-HOXA9-Induced Aberrant Nuclear Envelope Phenotype.	NUP98 HOXA9	2.86e-05	3	108	2	34831074
Pubmed	Identification of cooperative genes for NUP98-HOXA9 in myeloid leukemogenesis using a mouse model.	NUP98 HOXA9	2.86e-05	3	108	2	15454493
Pubmed	The Hsp70-Hsp90 co-chaperone Hop/Stip1 shifts the proteostatic balance from folding towards degradation.	ATP5PB RPL34 ACACA RPS11 NUP98 SF3B1 XPO5 FANCI PLEC EXOC4	3.11e-05	638	108	10	33239621
Pubmed	Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype.	TEAD2 TEAD1 TEAD3	3.19e-05	20	108	3	18978355
Pubmed	LRRC31 inhibits DNA repair and sensitizes breast cancer brain metastasis to radiation therapy.	ACACA MYO5A MYO5C XPO5 PI4KA PLEC	4.17e-05	202	108	6	33005030
Pubmed	Irisin Mediates Effects on Bone and Fat via αV Integrin Receptors.	SELENOT ATP5PB RPL34 TMEM53 ACACA PDK3 RPS11 SHMT2 POMGNT1 CHD8 FAT1 CRLS1 ATAD3C PLEC TAP2	4.30e-05	1451	108	15	30550785
Pubmed	Large-scale mapping of human protein-protein interactions by mass spectrometry.	ATP5PB AMFR RPL34 ACACA RPS11 NUP98 SHMT2 TRRAP SF3B1 XPO5 FANCI ASPM ELF3 EXOC4	4.48e-05	1284	108	14	17353931
Pubmed	Tead4 is required for specification of trophectoderm in pre-implantation mouse embryos.	TEAD2 TEAD1 TEAD3	4.93e-05	23	108	3	18083014
Pubmed	Cytokinesis involves a nontranscriptional function of the Hippo pathway effector YAP.	TEAD1 TEAD3 PLEC	4.93e-05	23	108	3	26933062
Pubmed	YAP/TEAD-mediated transcription controls cellular senescence.	TEAD1 TEAD3	5.71e-05	4	108	2	23576552
Pubmed	Single-translocation and double-chimeric transcripts: detection of NUP98-HOXA9 in myeloid leukemias with HOXA11 or HOXA13 breaks of the chromosomal translocation t(7;11)(p15;p15).	NUP98 HOXA9	5.71e-05	4	108	2	11830496
Pubmed	Tissue-specific kinase expression and activity regulate flux through the pyruvate dehydrogenase complex.	PDK2 PDK3	5.71e-05	4	108	2	30482839
Pubmed	A murine model of CML blast crisis induced by cooperation between BCR/ABL and NUP98/HOXA9.	NUP98 HOXA9	5.71e-05	4	108	2	12032333
Pubmed	Nup98-HoxA9 immortalizes myeloid progenitors, enforces expression of Hoxa9, Hoxa7 and Meis1, and alters cytokine-specific responses in a manner similar to that induced by retroviral co-expression of Hoxa9 and Meis1.	NUP98 HOXA9	5.71e-05	4	108	2	12082612
Pubmed	HOXA9 activates transcription of the gene encoding gp91Phox during myeloid differentiation.	NUP98 HOXA9	5.71e-05	4	108	2	15681849
Pubmed	Alternative splicing in class V myosins determines association with Rab10.	MYO5A MYO5C	5.71e-05	4	108	2	19008234
Pubmed	Identification and characterization of FAM124B as a novel component of a CHD7 and CHD8 containing complex.	CHD8 CHD7	5.71e-05	4	108	2	23285124
Pubmed	Paralogous mouse Hox genes, Hoxa9, Hoxb9, and Hoxd9, function together to control development of the mammary gland in response to pregnancy.	HOXA9 HOXD9	5.71e-05	4	108	2	9892669
Pubmed	Three members of the human pyruvate dehydrogenase kinase gene family are direct targets of the peroxisome proliferator-activated receptor beta/delta.	PDK2 PDK3	5.71e-05	4	108	2	17669420
Pubmed	Differing roles of pyruvate dehydrogenase kinases during mouse oocyte maturation.	PDK2 PDK3	5.71e-05	4	108	2	25991547
Pubmed	Cortical astrocyte N-methyl-D-aspartate receptors influence whisker barrel activity and sensory discrimination in mice.	GRIN1 ITPR2	5.71e-05	4	108	2	38383567
Pubmed	Preso regulates NMDA receptor-mediated excitotoxicity via modulating nitric oxide and calcium responses after traumatic brain injury.	FRMPD4 GRIN1	5.71e-05	4	108	2	31235685
Pubmed	VGLL3 operates via TEAD1, TEAD3 and TEAD4 to influence myogenesis in skeletal muscle.	TEAD1 TEAD3	5.71e-05	4	108	2	31138678
Pubmed	cDNA cloning and characterization of mouse DTEF-1 and ETF, members of the TEA/ATTS family of transcription factors.	TEAD2 TEAD3	5.71e-05	4	108	2	9502435
Pubmed	Diversity of the pyruvate dehydrogenase kinase gene family in humans.	PDK2 PDK3	5.71e-05	4	108	2	7499431
Pubmed	Myosin V transports secretory vesicles via a Rab GTPase cascade and interaction with the exocyst complex.	MYO5A EXOC4	5.71e-05	4	108	2	22172676
Pubmed	Mechanisms and Consequences of Dopamine Depletion-Induced Attenuation of the Spinophilin/Neurofilament Medium Interaction.	MYO5A SYNPO GRIN1 ATAD3C PLEC	5.74e-05	131	108	5	28634551
Interaction	CTTN interactions	MYO5A RRP1B PDK2 NCKIPSD SHMT2 SYNPO GRIN1 TEAD1 MYO5C BICD1 PLEC CLUH	4.38e-06	450	106	12	int:CTTN
Interaction	IFNA16 interactions	IFNA7 IFNA16 UBR3	4.87e-06	7	106	3	int:IFNA16
Interaction	DCPS interactions	DOCK2 MYO1G RRP1B RPS11 NUP98 TENT5C GINS4 SF3B1 NXT1 PLEC PHIP	7.32e-06	394	106	11	int:DCPS
Interaction	IFNA7 interactions	IFNA7 IFNA16 UBR3	1.16e-05	9	106	3	int:IFNA7
Cytoband	15q21	MYO5A MYO5C	2.97e-04	11	108	2	15q21
Cytoband	6p21.1	MRPS10 XPO5 RSPH9	9.12e-04	80	108	3	6p21.1
Cytoband	19q13.3	TEAD2 RPS11 GIPR	9.80e-04	82	108	3	19q13.3
Cytoband	9p22	IFNA7 IFNA16	1.59e-03	25	108	2	9p22
Cytoband	5q33.1	SYNPO FAT2	1.72e-03	26	108	2	5q33.1
Cytoband	3q25.1	SELENOT AADACL2	2.76e-03	33	108	2	3q25.1
GeneFamily	TEA domain transcription factors	TEAD2 TEAD1 TEAD3	3.20e-07	4	79	3	1183
GeneFamily	Myosins, class V	MYO5A MYO5C	5.64e-05	3	79	2	1100
GeneFamily	HOXL subclass homeoboxes	GSX1 HOXA9 HOXD9	1.52e-03	52	79	3	518
GeneFamily	Dyneins, axonemal	DNAH10 DNAH17	2.46e-03	17	79	2	536
GeneFamily	Cadherin related	FAT1 FAT2	2.46e-03	17	79	2	24
GeneFamily	WD repeat domain containing\|DDB1 and CUL4 associated factors	PHIP BRWD1	2.76e-03	18	79	2	498
ToppCell	3'-GW_trimst-2-LargeIntestine-Epithelial-epithelial_progenitor_cell-TA\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	MYO5C HOXA9 ASPM ELF3 FRMPD3 PLXNB1	5.15e-06	180	108	6	271ee52ed8f21f78ddf68e52fc88fe582701675e
ToppCell	COVID-19-Heart-Macrophage\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 MYO5A DENND1A CYRIB GRK3 HPGDS	6.81e-06	189	108	6	2586f4088721c5debec86c2b211b739fd33713eb
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 MYO5A SLC18B1 DENND1A ITPR2 HPGDS	7.01e-06	190	108	6	f573fef3762a30c38cf8fa7f45df0ffbb49dc873
ToppCell	Immune-interstitial_macrophage_(C1Q_positive)\|World / Lineage, Cell type, age group and donor	DOCK2 MYO5A SLC18B1 DENND1A ITPR2 HPGDS	7.67e-06	193	108	6	64d598162a256ac6c9f8280c8a9133661dfbb10f
ToppCell	COVID-19-Myeloid-Monocyte-derived_macrophages\|COVID-19 / group, cell type (main and fine annotations)	DOCK2 MYO5A DENND1A CYRIB ITPR2 GRK3	8.14e-06	195	108	6	c172c5599379c29123340621a36bfb1fc90c2115
ToppCell	COVID-19-lung-Macrophage_VCANhi_FCN1hi\|lung / Disease (COVID-19 only), tissue and cell type	DOCK2 MYO1G NLRP12 DENND1A CYRIB GRK3	8.62e-06	197	108	6	a0f8a992282a6d64890f5574c7c9741fcb38dadd
ToppCell	LPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type	CHD7 MYO5C ELF3 FRMPD3 PHIP PLXNB1	8.62e-06	197	108	6	3d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCell	LPS_only-Hematopoietic_Mast-Mast_cells-T-cells\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	SELENOT DOCK2 MYO1G MYO5A HPGDS	3.26e-05	150	108	5	ccb782fbcb3122266354a112a9a850506664f44d
ToppCell	5'-GW_trimst-2-LargeIntestine-Epithelial-Tuft-related-Tuft\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3C MYO5C SLC9A5 HPGDS ELF3	4.70e-05	162	108	5	80619a93c57fe16daf91dc571874ef9ac888953d
ToppCell	droplet-Liver-Npc-18m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL34 FRMPD4 MYO5A CYRIB GRK3	5.59e-05	168	108	5	ce5e92a1df3acfa5cd8d5a134e4af231dc592a13
ToppCell	droplet-Liver-Npc-18m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	RPL34 FRMPD4 MYO5A CYRIB GRK3	5.59e-05	168	108	5	22c89d4eb44573f6301069ec7ca7cbd0dd958403
ToppCell	droplet-Trachea-nan-3m-Myeloid-macrophage\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 MYO1G RPS11 CHD7 CYRIB	6.25e-05	172	108	5	f6c00a6a7e81aaf96c55eb3a3c88e3719f102ea0
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-myeloid_cell\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 MYO1G CYRIB GRK3 HPGDS	6.25e-05	172	108	5	6b01448443cf8392ed8248ff452b80c31240b85d
ToppCell	droplet-Trachea-3m-Hematologic-myeloid-tracheal_macrophage\|3m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	DOCK2 MYO1G RPS11 CHD7 CYRIB	6.25e-05	172	108	5	f3bbe3f069ad070778430d1a6cd9db0a76deb8de
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-myeloid_leukocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G PDK3 CYRIB HOXA9 GRK3	6.25e-05	172	108	5	a125ac2db9c8ece95970a93aa6f7918d1dcef886
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 MYO1G CYRIB GRK3 HPGDS	6.25e-05	172	108	5	0c0ae2da3cba6022403434567800f16e61a34a2b
ToppCell	droplet-Fat-BAT+GAT+MAT-30m-Myeloid-nan\|Fat / Fat_BAT_GAT_MAT_SCAT - method, tissue, subtissue, age, lineage, cell ontology and free annotation	DOCK2 MYO1G CYRIB GRK3 HPGDS	6.25e-05	172	108	5	d80c207f3489be2da2f40f47a7835cb73c949c3e
ToppCell	droplet-Liver-LIVER-NPC-1m-Myeloid-macrophage/monocyte\|Liver / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	MYO1G PDK3 CYRIB HOXA9 GRK3	6.25e-05	172	108	5	6aab59add5b180cee0ca31179c620e89d352d5c1
ToppCell	3'-Broncho-tracheal-Epithelial-Epithelial_transtional-secretory-nasal_mucosa_goblet_cell-Goblet_(nasal)-Goblet_(nasal)_L.0.2.2.2\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	ACACA FAT2 ELF3 CLUH PLXNB1	6.60e-05	174	108	5	207aa0118633cbe9a65839bbb1bb3ba9f8118ad2
ToppCell	CV-Mild-6\|Mild / Virus stimulation, Condition and Cluster	DNAH10 NUP98 CHD8 RSPH3 FRMPD3	6.78e-05	175	108	5	c4d530dbb37942427c9cd0a1533faeb6a3a45381
ToppCell	Brain_organoid-organoid_Kanton_Nature-Organoid-2M-Radial_glial-RGCs_early_1\|Organoid-2M / Sample Type, Dataset, Time_group, and Cell type.	PAGE1 GSX1 RPL34 RPS11 SHMT2	6.96e-05	176	108	5	2a15437c5f5dbf6398d5ea70050632c24a7dc66c
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)	NUP98 SHMT2 MORC2 DNAH17 CLUH	7.54e-05	179	108	5	42f3c040f504a91cc69292d39d22b5715c12526f
ToppCell	BAL-Control-Myeloid-cDC-cDC-cDC_7\|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)	NUP98 SHMT2 MORC2 DNAH17 CLUH	7.54e-05	179	108	5	063c05753ef1b4a18bc1ebbcae62c8cd25d11070
ToppCell	PND10-Immune\|PND10 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif	DOCK2 MYO1G RPL34 RPS11 CYRIB	7.95e-05	181	108	5	ef424f7eefe1b190a2be2ebcae7652eb8e7ba883
ToppCell	3'-Child04-06-SmallIntestine-Epithelial-Tuft-related-Tuft\|Child04-06 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3C ITPR2 HPGDS ELF3 TMEM63A	8.81e-05	185	108	5	686ed7550c6acd18e71e0076936ec5b07389adbd
ToppCell	Children_(3_yrs)-Immune-interstitial_macrophage_(C1Q_positive)-D046\|Children_(3_yrs) / Lineage, Cell type, age group and donor	MYO5A SLC18B1 DENND1A ITPR2 HPGDS	8.81e-05	185	108	5	8207f9eff113eed429e961748c6b17d672a13b33
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK2 MYO5A SLC18B1 ITPR2 HPGDS	9.27e-05	187	108	5	39b99f46b723f7f3c44880d7fe8642cbad558b8a
ToppCell	Control-Myeloid-Monocytes\|Control / group, cell type (main and fine annotations)	DOCK2 MYO1G NLRP12 DENND1A GRK3	9.74e-05	189	108	5	3335d16bd0ffa0c1ddd06d7da645299148130c3f
ToppCell	5'-Adult-LargeIntestine-Epithelial-Tuft-related-Tuft\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	HTR3C ITPR2 HPGDS ELF3 TMEM63A	1.02e-04	191	108	5	54f07e4de61735051498846afb44b1798bed8144
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic-Non-classical_Monocyte\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 MYO1G NLRP12 CYRIB GRK3	1.02e-04	191	108	5	47a2afc4102199b4bc76bd01b2967c8016186462
ToppCell	facs-Lung-18m-Epithelial\|18m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	MYO5C FAT1 FAT2 ELF3 PLXNB1	1.07e-04	193	108	5	8e934f127bc763e905c788beabfa867bd559b682
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like-IPCs\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TEAD2 RPS11 CHD7 BICD1 ITPR2	1.07e-04	193	108	5	2088f1d210c73f74685492c63065c62ac3f553e9
ToppCell	Brain_organoid-organoid_Paulsen_bioRxiv-3.5_mon-IPC_like\|3.5_mon / Sample Type, Dataset, Time_group, and Cell type.	TEAD2 RPS11 CHD7 BICD1 ITPR2	1.07e-04	193	108	5	f24bae40f5cbcfece04fbefe4e3de1b88ac90de4
ToppCell	Fetal_29-31_weeks-Immune-alveolar_macrophage_(MARCO_positive)-D150\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK2 MYO5A SLC18B1 ITPR2 HPGDS	1.07e-04	193	108	5	2d0dd2671ff27b922eb316f1ed0140353536ef30
ToppCell	facs-Trachea-nan-3m-Epithelial\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH3 MYO5C FAT2 ELF3 PLXNB1	1.10e-04	194	108	5	3701ca87c6dc9ccd7b4146e56371546174d26c36
ToppCell	facs-Trachea-nan-3m-Epithelial-nan\|Trachea / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	KCNH3 MYO5C FAT2 ELF3 PLXNB1	1.10e-04	194	108	5	65f9bf126be26114c2c3f4c46d48318986212a92
ToppCell	IPF-Multiplet-Multiplet\|World / Disease state, Lineage and Cell class	DNAH10 TEAD1 AADACL2 ELF3 RSPH9	1.13e-04	195	108	5	21dbdc803c6947024dc2416e9e21c2ef0af9bc31
ToppCell	COVID-19-lung-Macrophage_CD163hi_MERTKhi\|lung / Disease (COVID-19 only), tissue and cell type	DOCK2 MYO5A DENND1A CYRIB GRK3	1.13e-04	195	108	5	148fff8c3c9ba45ec36e98dff1be57e3f8294506
ToppCell	(3)_MNP-(3)_Macrophage_MARCOneg\|(3)_MNP / Lung cell shreds - cell class (v4) and cell subclass (v4)	MYO5A SLC18B1 SESN1 ITPR2 HPGDS	1.13e-04	195	108	5	e4b5e4b8832669fb4d1661ecd828b81e621d35c4
ToppCell	Fetal_29-31_weeks-Immune-interstitial_macrophage_(C1Q_positive)\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	DOCK2 MYO5A SLC18B1 ITPR2 HPGDS	1.13e-04	195	108	5	312d9625655b38f1a7c2bf8f8bb7b667ebdf9617
ToppCell	Children_(3_yrs)-Immune-monocyte\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 NLRP12 DENND1A CYRIB GRK3	1.16e-04	196	108	5	cacd69be72e6167814f7adea7c5fa114f3103bbb
ToppCell	IPF-Epithelial\|IPF / Disease state, Lineage and Cell class	DNAH10 TEAD1 AADACL2 ELF3 RSPH9	1.16e-04	196	108	5	87d9881cfec461a5d89b688a83749b618c519485
ToppCell	COVID-19-kidney-Macrophages\|COVID-19 / Disease (COVID-19 only), tissue and cell type	DOCK2 DENND1A CYRIB ITPR2 GRK3	1.18e-04	197	108	5	3912301018d0863144dcfac8d1fa8adc081748d7
ToppCell	Children_(3_yrs)-Immune\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 MYO5A DENND1A CYRIB GRK3	1.18e-04	197	108	5	f18807124b91310fcd84238484a80ecdba684679
ToppCell	COVID-19-lung-Macrophage_LDB2hi_OSMRhi_YAP1hi\|lung / Disease (COVID-19 only), tissue and cell type	DOCK2 MYO5A DENND1A CYRIB GRK3	1.18e-04	197	108	5	3896729740d151f0eb845f1961c7b969bfbdd28d
ToppCell	Control-Classical_Monocyte-cMono_2\|Classical_Monocyte / Disease condition and Cell class	SELENOT DOCK2 ATP5PB SF3B1 GRK3	1.18e-04	197	108	5	eb7610c9496a95a5fd866e16abcbc39b83abe617
ToppCell	LPS_only-Epithelial_alveolar-AT_1-Differentiating_AT2\|LPS_only / Treatment groups by lineage, cell group, cell type	GIPR FAT1 XPO5 TRABD ELF3	1.18e-04	197	108	5	6b6504c47c309bac4f790e2f372d454bbdea49e8
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Immune-Myeloid-Monocytic\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	DOCK2 MYO1G NLRP12 CYRIB GRK3	1.18e-04	197	108	5	1eb9ff8467118b943b5d443cb996168e1e1206b5
ToppCell	Adult-Immune\|Adult / Lineage, Cell type, age group and donor	DOCK2 MYO5A DENND1A CYRIB GRK3	1.21e-04	198	108	5	9bfd7b88aa646eaf5eddb15cf985c7ca910cb35e
ToppCell	Immune-monocyte\|World / Lineage, Cell type, age group and donor	DOCK2 NLRP12 DENND1A CYRIB GRK3	1.21e-04	198	108	5	d3622da252fd580f1dc5c7478a8e23df5ec083cf
ToppCell	5'-GW_trimst-2-LargeIntestine-Hematopoietic-Myeloid\|GW_trimst-2 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	DOCK2 MYO5A ITPR2 GRK3 HPGDS	1.24e-04	199	108	5	f34c15df58fbdc6c90e30800e26fabbf828ad10b
ToppCell	Tracheal-NucSeq\|Tracheal / Cell types per location group and 10X technology with lineage, and cell group designations	ACACA DENND1A ITPR2 UBR3 EXOC4	1.24e-04	199	108	5	94b94b17ca18b8dc27b91da1f2ccf89e03cc7035
ToppCell	LPS_IL1RA_TNF-Epithelial_alveolar-AT_2-Differentiating_AT2\|LPS_IL1RA_TNF / Treatment groups by lineage, cell group, cell type	MYO5C FAT1 TRABD ELF3 PLXNB1	1.27e-04	200	108	5	e8db082aa4d0597500e4f16a5c0ea3e62c6c59ae
ToppCell	Children_(3_yrs)-Immune-monocyte-D139\|Children_(3_yrs) / Lineage, Cell type, age group and donor	DOCK2 NLRP12 DENND1A CYRIB GRK3	1.27e-04	200	108	5	881ab995c90d75fd987d6e8f1f926a4bfcc4235f
ToppCell	Fetal_brain-organoid_Tanaka_cellReport-GW12-Mesenchymal-Unfolded_protein_responsible_cell\|GW12 / Sample Type, Dataset, Time_group, and Cell type.	DNAH10 PEX11A TRABD CLUH TMEM63A	1.27e-04	200	108	5	6b7314c425f6b40f1301dd39cc02b0436e96a2ec
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2\|World / Primary Cells by Cluster	GINS4 CHD7 FANCI ASPM PHIP	1.27e-04	200	108	5	4923d7a4f00853c4d76fc1cc0fa82d522a2302e7
ToppCell	Brain_organoid-organoid_Tanaka_cellReport-3m-Neuronal-Neuron\|3m / Sample Type, Dataset, Time_group, and Cell type.	RPL34 RPS11 CHD7 BICD1 ITPR2	1.27e-04	200	108	5	3d134ae3c48ff4d1849db4fbe44ff73fb6c8c779
ToppCell	Non-neuronal-Dividing-IPC-IPC-div2-5\|World / Primary Cells by Cluster	GINS4 CHD7 FANCI ASPM PHIP	1.27e-04	200	108	5	dc1c1506823eaa105f1532c6b5d4efa14e788314
Drug	Isoquinoline, 6,7-dimethoxy-1-methyl-1,2,3,4-tetrahydro, hydrochloride; Down 200; 16.4uM; MCF7; HT_HG-U133A	TENT5C BICD1 GRK3 TRABD MTM1 GPC4 PLEC CLUH PLXNB1	3.43e-07	194	107	9	2824_DN
Drug	Resveratrol [501-36-0]; Down 200; 17.6uM; MCF7; HT_HG-U133A	NUP98 TEAD3 BICD1 ASPM ZNF747 ELF3 TMEM63A BRWD1	3.53e-06	192	107	8	2865_DN
Drug	Quercetine dihydrate [6151-25-3]; Down 200; 11.8uM; MCF7; HT_HG-U133A	RRP1B NUP98 TENT5C PEX11A ITPR2 TRABD MTM1	2.30e-05	180	107	7	2859_DN
Drug	17-AAG; Down 200; 1uM; PC3; HT_HG-U133A	AMFR GINS4 PEX11A CYRIB BICD1 PLXNB1 TMEM63A	3.26e-05	190	107	7	4442_DN
Drug	Benzylpenicillin sodium [69-57-8]; Down 200; 11.2uM; MCF7; HT_HG-U133A	GINS4 NPTXR MTM1 ZNF747 ARHGEF4 PLXNB1 TMEM63A	3.37e-05	191	107	7	6839_DN
Drug	Mecamylamine hydrochloride [826-39-1]; Down 200; 19.6uM; MCF7; HT_HG-U133A	TMEM53 RRP1B TENT5C GINS4 GPC4 ZNF747 PLXNB1	3.84e-05	195	107	7	3525_DN
Drug	Atractyloside potassium salt [102130-43-8]; Down 200; 5uM; PC3; HT_HG-U133A	TMEM53 RRP1B CHD7 TRABD MTM1 ARHGEF4 BRWD1	3.84e-05	195	107	7	7393_DN
Drug	estradiol, USP; Down 200; 0.01uM; ssMCF7; HG-U133A	GRIN1 BICD1 BMP10 HPGDS MTM1 GPC4 DAGLA	3.97e-05	196	107	7	373_DN
Drug	ICI 182,780; Down 200; 1uM; ssMCF7; HG-U133A	RRP1B PDK2 POMGNT1 PEX11A BICD1 FANCI BRWD1	3.97e-05	196	107	7	523_DN
Drug	Tetracaone hydrochloride [136-47-0]; Up 200; 13.2uM; MCF7; HT_HG-U133A	PDK3 TENT5C BICD1 GIPR USP2 ZNF747 ARHGEF4	4.23e-05	198	107	7	7473_UP
Drug	Pentolinium bitartrate [52-62-0]; Down 200; 7.4uM; MCF7; HT_HG-U133A	TMEM53 PDK3 POMGNT1 CYRIB NPTXR GPC4 ZNF747	4.23e-05	198	107	7	2305_DN
Drug	Phentolamine hydrochloride [73-05-2]; Down 200; 12.6uM; MCF7; HT_HG-U133A	AMFR AMPD1 PDK2 CYRIB DNAH17 ARHGEF4 PLEC	4.37e-05	199	107	7	3860_DN
Drug	Heliotrine [303-33-3]; Up 200; 12.8uM; MCF7; HT_HG-U133A	SYNPO CYRIB ITPR2 HOXA9 HPGDS TRABD TMEM63A	4.37e-05	199	107	7	3615_UP
Drug	AC1L9LMC	ACACA MYO5A ARSI HOXA9 PLEC	4.53e-05	83	107	5	CID000448113
Disease	neutrophil measurement	NLRP12 TENT5C CHD7 FAT2 PLEC TMEM63A	3.20e-05	177	100	6	EFO_0803548
Disease	phosphatidylcholine 38:4 measurement	FRMPD4 ITPR2 DAGLA	1.16e-04	28	100	3	EFO_0010386
Disease	CHARGE syndrome (implicated_via_orthology)	CHD8 CHD7	2.36e-04	7	100	2	DOID:0050834 (implicated_via_orthology)
Disease	immature granulocyte measurement	NLRP12 CHD7	2.36e-04	7	100	2	EFO_0803543
Disease	acute myeloid leukemia (implicated_via_orthology)	NUP98 SF3B1	7.34e-04	12	100	2	DOID:9119 (implicated_via_orthology)
Disease	mitochondrial DNA measurement	NCKIPSD CHD7 PPY HPGDS FANCI TRABD	8.95e-04	328	100	6	EFO_0006312
Disease	Autosomal recessive limb-girdle muscular dystrophy	POMGNT1 PLEC	1.01e-03	14	100	2	cv:C2931907
Disease	Leukemia, Myelocytic, Acute	NUP98 HOXA9 SF3B1 FANCI	2.89e-03	173	100	4	C0023467

Protein segments in the cluster

Peptide	Gene	Start	Entry
FYLRLGLRIRDMYVS	AADACL2	381	Q6P093
RLCRSRQIYDAYIMK	GRK3	101	P35626
KVLLRVRMLYYLRQE	CHD8	1576	Q9HCK8
NRVMLDYYRQSRVTR	BICD1	531	Q96G01
ILVLSYFRYMRIYRR	CATSPERE	921	Q5SY80
REYLYRYRTMGNVAR	ARSI	246	Q5FYB1
MGLVYARIYRVAKLR	ADRA2C	226	P18825
YAEAMALPLYRRTIR	DPH6	61	Q7L8W6
LRRDVLYYKGRLDMD	ARHGEF4	536	Q9NR80
RMAALEVYVRRAYIA	ACACA	1146	Q13085
QIMFYVAIRRRPSLY	HTR3C	236	Q8WXA8
RLILERLQVMYTVGY	GIPR	131	P48546
RAMRYYYKREILERV	ELF3	331	P78545
RRTNVAQIRMAYRYE	AMPD1	716	P23109
IYRLITRNSYEREMF	CHD7	1411	Q9P2D1
NKVLLRVRMLYYLRQ	CHD7	1736	Q9P2D1
RVRMLYYLRQEVIGD	CHD7	1741	Q9P2D1
MNERALLSSYLVAYR	FAM200A	56	Q8TCP9
LRIQFFLQMAVYRRR	ASPM	2841	Q8IZT6
MALEVTYRERLYRVY	ATP5PB	176	P24539
NLRLQRMIRYSATLF	RBSN	351	Q9H1K0
SAYARLIDYARMREV	SHMT2	226	P34897
YMLRLCYRVLRHSQQ	ITPR2	551	Q14571
LSVRLDYRISYMLSI	ITPR2	981	Q14571
RLIYRRRPMIYVESS	PAGE1	6	O75459
TAIIQRMYARRFLYH	KCNH3	501	Q9ULD8
DYELMPRVYTLRIRA	FAT1	526	Q14517
VRLMLYEGFYDVLRR	FANCI	601	Q9NVI1
LVYLDYIRVIEMLRH	NUP98	1691	P52948
ARLLERMFRLVNSQY	GPC4	166	O75487
LTYFNMRGRAEIIRY	HPGDS	6	O60760
MRGRAEIIRYIFAYL	HPGDS	11	O60760
LLYARDIPRYKRMVE	PLXNB1	2036	O43157
KRMVERYYADIRQTV	PLXNB1	2046	O43157
DYELMKRIYTFRVRA	FAT2	521	Q9NYQ8
IVEFSRYLSQMRNLR	PRAMEF18	221	Q5VWM3
FASNMYLSRLRRIEI	GSX1	166	Q9H4S2
LFNMYLTRDRRYEVA	HOXA9	226	P31269
LAVRKYFQRITLYLM	IFNA7	141	P01567
VYRLEYMRVLRSTDP	PI4KA	896	P42356
FNMYLTRDRRYEVAR	HOXD9	306	P28356
ISYYTRMKDRLLERI	TMEM63A	321	O94886
ISIPIRNNYMYARVR	NPTXR	296	O95502
ADLRRYINMLTRPRY	PPY	51	P01298
DRFYLSRISIRMLIN	PDK2	156	Q15119
RAYAAVLYIDPRMRI	MORC2	241	Q9Y6X9
ISMSAYLREQRRELY	EXOC4	451	Q96A65
RLYTLVQRDRMIYDG	BMP10	146	O95393
REEMYIRYLYKLRDL	DOCK2	1216	Q92608
RLCRTYLAEYIRTEM	DNAH17	4101	Q9UFH2
LTMFYYICLRRRART	FBXL4	11	Q9UKA2
YRKLMRRYSISELDQ	FRMPD3	1421	Q5JV73
YYRLLVDSRRSIFNM	FRMPD4	511	Q14CM0
RARLVRMYLNEYVLK	ATAD3C	306	Q5T2N8
DLYTIRMRLVNRFYR	BRWD1	1206	Q9NSI6
YMDRARQYSTRLAVL	LAMTOR1	81	Q6IAA8
RDSMQYVLYVRLAIL	DAGLA	91	Q9Y4D2
HLYASMLYERRILII	DENND1A	186	Q8TEH3
FSYYRRTLSRMRINN	CYRIB	156	Q9NUQ9
VMELRYRDVQERYRT	DNAH10	1121	Q8IVF4
RDVMLIAAVFYVRYR	CRLS1	201	Q9UJA2
MVQRLTYRRRLSYNT	RPL34	1	P49207
VNVYYTTMDKRRRLL	NXT1	21	Q9UKK6
KMQRTIVIRRDYLHY	RPS11	81	P62280
LRNLRDFLLVYNRMT	TIMM10B	11	Q9Y5J6
GIIIRYELYMRRLRS	USH2A	1271	O75445
RVQYEMRTLYRCLEL	MRPS10	131	P82664
YRRVFEEYMRVISQR	SELENOT	51	P62341
SLMLVKRDYRYDRVL	RSPH9	31	Q9H1X1
MQAELLYALRAITRY	SESN1	476	Q9Y6P5
RLRLDKYYMLIRLVL	RRP1B	111	Q14684
EMERIRYVLSSYLRC	GINS4	81	Q9BRT9
RYVLSSYLRCRLMKI	GINS4	86	Q9BRT9
AMGLFYLLEYSRRKR	SLC18B1	421	Q6NT16
ELYARRQSRMEKYVI	SYNPO	726	Q8N3V7
LAVRKYFQRITLYLM	IFNA16	141	P05015
RPNYLYRMLRSLLSA	POMGNT1	311	Q8WZA1
LRLEYLQMLYVRRVC	PRAMEF22	266	A3QJZ6
KYLSQLLMRRSAYRI	SLC9A5	506	Q14940
YTMSRINLRIREQLF	TAP2	216	Q03519
MYGRNELIARYIKLR	TEAD2	76	Q15562
RLFRATQYTCMLLRY	PEX11A	16	O75192
LLGYRMRRNAVSIYI	MRGPRX4	51	Q96LA9
LDRFYTNRISFRMLI	PDK3	151	Q15120
AYYQMEHRASLRLLL	NCKIPSD	446	Q9NZQ3
RSKYDYLMILRRVVN	TENT5C	301	Q5VWP2
MQLRYLFHEVQRRIR	AMFR	296	Q9UKV5
ALSLLYRARYLMLLV	CLUH	1081	O75153
VRRYIIYNSRPMRLA	TMEM268	91	Q5VZI3
IMYDRRVIRGNTYAL	RSPH3	191	Q86UC2
ALRFYRRLLQMGIYN	TTC8	371	Q8TAM2
RYMELLALRDEYIKR	MTM1	556	Q13496
QRLENRFYRRVSSLM	PHIP	1211	Q8WWQ0
VYLTYMLRQAARRLE	TRABD	261	Q9H4I3
YANYYTREVMLILIR	SF3B1	761	O75533
MYGRNELIARYIKLR	TEAD3	66	Q99594
PAQRALYRDVMRETY	ZNF747	56	Q9BV97
GVMLYRYVLELLQTR	TMEM53	116	Q6P2H8
YEALRPRYLEIRAVM	XPO5	1101	Q9HAV4
QMYRRVYRLHERLVA	PLEC	606	Q15149
RRYDLRMGQLFSDYV	WDR83	176	Q9BRX9
RALYRDVMRETYGHL	ZNF689	51	Q96CS4
RTVYRRDVQSAMDRY	UBR3	871	Q6ZT12
MYGRNELIARYIKLR	TEAD1	66	P28347
LRDYCLQRLYMRDLH	USP2	291	O75604
RMHRLYLARRSFIIQ	TSPY26P	176	Q9H489
MKRRVYERLLYVTCS	TRRAP	2466	Q9Y4A5
TRKVRYTERVDYLMQ	USP13	486	Q92995
QETYRDYVRRKFRLM	NLRP12	126	P59046
LYKLDPDRQYRVMRA	MYO1G	896	B0I1T2
RYRIIGANMRTYLLE	MYO5A	231	Q9Y4I1
YLVRSLYQLIRMATI	MYO5C	821	Q9NQX4
RTIRYVRYESELQMP	NAA30	211	Q147X3
RGYIAMLAVDSKYRR	NAA30	281	Q147X3
IYFRRQVELSTMYRH	GRIN1	691	Q05586