Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyMolecularFunction	G protein-coupled receptor activity	OPN1MW2 OR14K1 OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 ADGRG1 OPN1MW GPR132	3.87e-06	884	46	11	GO:0004930
GeneOntologyMolecularFunction	G protein-coupled photoreceptor activity	OPN1MW2 OPN1MW3 OPN1MW	5.11e-06	15	46	3	GO:0008020
GeneOntologyMolecularFunction	photoreceptor activity	OPN1MW2 OPN1MW3 OPN1MW	7.61e-06	17	46	3	GO:0009881
GeneOntologyMolecularFunction	antiporter activity	SLC32A1 SLC35E2A SLC44A2 SLC7A5 SLC35E2B	1.60e-05	138	46	5	GO:0015297
GeneOntologyMolecularFunction	transmembrane signaling receptor activity	OPN1MW2 OR14K1 OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 ADGRG1 OPN1MW GPR132 IL4R	4.00e-05	1353	46	12	GO:0004888
GeneOntologyMolecularFunction	secondary active transmembrane transporter activity	SLC6A1 SLC32A1 SLC35E2A SLC44A2 SLC7A5 SLC35E2B	5.74e-05	296	46	6	GO:0015291
GeneOntologyMolecularFunction	gamma-aminobutyric acid transmembrane transporter activity	SLC6A1 SLC32A1	1.85e-04	9	46	2	GO:0015185
GeneOntologyMolecularFunction	transporter activity	SLC6A1 SLC32A1 GJB3 TRPC4AP CLCNKA SLC35E2A SLC44A2 SLC7A5 ATP10B SLC35E2B	5.83e-04	1289	46	10	GO:0005215
GeneOntologyMolecularFunction	active transmembrane transporter activity	SLC6A1 SLC32A1 SLC35E2A SLC44A2 SLC7A5 SLC35E2B	7.50e-04	477	46	6	GO:0022804
GeneOntologyMolecularFunction	secondary active monocarboxylate transmembrane transporter activity	SLC6A1 SLC32A1	8.66e-04	19	46	2	GO:0015355
GeneOntologyMolecularFunction	organic cation transmembrane transporter activity	SLC32A1 SLC44A2 SLC7A5	9.24e-04	83	46	3	GO:0015101
GeneOntologyMolecularFunction	transmembrane transporter activity	SLC6A1 SLC32A1 GJB3 TRPC4AP CLCNKA SLC35E2A SLC44A2 SLC7A5 SLC35E2B	1.29e-03	1180	46	9	GO:0022857
GeneOntologyMolecularFunction	amino acid transmembrane transporter activity	SLC6A1 SLC32A1 SLC7A5	1.82e-03	105	46	3	GO:0015171
GeneOntologyMolecularFunction	amino acid:monoatomic cation symporter activity	SLC6A1 SLC32A1	2.03e-03	29	46	2	GO:0005416
GeneOntologyMolecularFunction	neutral L-amino acid transmembrane transporter activity	SLC32A1 SLC7A5	4.02e-03	41	46	2	GO:0015175
GeneOntologyCellularComponent	photoreceptor disc membrane	OPN1MW2 OPN1MW3 OPN1MW	2.85e-05	26	48	3	GO:0097381
Domain	Opsin_red/grn	OPN1MW3 OPN1MW	1.86e-05	3	47	2	IPR000378
Domain	7tm_1	OR14K1 OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 OPN1MW GPR132	4.06e-05	677	47	9	PF00001
Domain	G_PROTEIN_RECEP_F1_1	OR14K1 OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 OPN1MW GPR132	4.45e-05	685	47	9	PS00237
Domain	G_PROTEIN_RECEP_F1_2	OR14K1 OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 OPN1MW GPR132	4.76e-05	691	47	9	PS50262
Domain	GPCR_Rhodpsn	OR14K1 OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 OPN1MW GPR132	4.81e-05	692	47	9	IPR000276
Domain	GPCR_Rhodpsn_7TM	OPN1MW3 OR51B5 GPR15 GPR20 OR51B6 OR5B17 OPN1MW GPR132	2.40e-04	670	47	8	IPR017452
Domain	Sugar_P_trans_dom	SLC35E2A SLC35E2B	2.75e-04	10	47	2	IPR004853
Domain	OPSIN	OPN1MW3 OPN1MW	2.75e-04	10	47	2	PS00238
Domain	TPT	SLC35E2A SLC35E2B	2.75e-04	10	47	2	PF03151
Domain	Opsin	OPN1MW3 OPN1MW	3.36e-04	11	47	2	IPR001760
Domain	ZF_BBOX	TRIM43B MYCBP2 TRIM43	1.07e-03	80	47	3	PS50119
Domain	Znf_B-box	TRIM43B MYCBP2 TRIM43	1.11e-03	81	47	3	IPR000315
Domain	ARM-type_fold	STK36 TRPC4AP ATM RALGAPA2	1.03e-02	339	47	4	IPR016024
Pathway	REACTOME_THE_RETINOID_CYCLE_IN_CONES_DAYLIGHT_VISION	OPN1MW2 OPN1MW3	1.76e-04	8	36	2	MM14880
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A1 SLC32A1 TRPC4AP CLCNKA SLC44A2 SLC7A5 ATP10B SOAT2	2.58e-04	681	36	8	MM14985
Pathway	REACTOME_OPSINS	OPN1MW2 OPN1MW3	2.82e-04	10	36	2	MM15063
Pathway	REACTOME_TRANSPORT_OF_SMALL_MOLECULES	SLC6A1 SLC32A1 TRPC4AP CLCNKA SLC44A2 SLC7A5 ATP10B SOAT2	4.37e-04	736	36	8	M27287
Pathway	REACTOME_INTERLEUKIN_4_AND_INTERLEUKIN_13_SIGNALING	SOCS5 IL4R	5.66e-04	14	36	2	MM15321
Pubmed	Human L- and M-opsins restore M-cone function in a mouse model for human blue cone monochromacy.	OPN1MW2 OPN1MW3 OPN1MW	1.05e-08	4	49	3	29386880
Pubmed	Molecular genetics of human color vision: the genes encoding blue, green, and red pigments.	OPN1MW2 OPN1MW3 OPN1MW	2.62e-08	5	49	3	2937147
Pubmed	Hydrogen/Deuterium Exchange Mass Spectrometry of Human Green Opsin Reveals a Conserved Pro-Pro Motif in Extracellular Loop 2 of Monostable Visual G Protein-Coupled Receptors.	OPN1MW2 OPN1MW	1.94e-06	2	49	2	28402104
Pubmed	SLC35E2 promoter mutation as a prognostic marker of esophageal squamous cell carcinoma.	SLC35E2A SLC35E2B	1.94e-06	2	49	2	35247439
Pubmed	Defective colour vision associated with a missense mutation in the human green visual pigment gene.	OPN1MW2 OPN1MW	1.94e-06	2	49	2	1302020
Pubmed	Position of a 'green-red' hybrid gene in the visual pigment array determines colour-vision phenotype.	OPN1MW2 OPN1MW	1.94e-06	2	49	2	10319869
Pubmed	Molecular determinants of human red/green color discrimination.	OPN1MW2 OPN1MW	5.83e-06	3	49	2	8185948
Pubmed	X-linked cone dystrophy caused by mutation of the red and green cone opsins.	OPN1MW2 OPN1MW	5.83e-06	3	49	2	20579627
Pubmed	Expression of red/green-cone opsin mutants K82E, P187S, M273K result in unique pathobiological perturbations to cone structure and function.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	38410159
Pubmed	Chloride-dependent spectral tuning mechanism of L-group cone visual pigments.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	23350963
Pubmed	Distinct contributions of rod, cone, and melanopsin photoreceptors to encoding irradiance.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	20471354
Pubmed	Fetal hemoglobin in sickle cell anemia: genome-wide association studies suggest a regulatory region in the 5' olfactory receptor gene cluster.	OR51B5 OR51B6	5.83e-06	3	49	2	20018918
Pubmed	Multiple hypothalamic cell populations encoding distinct visual information.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	21224225
Pubmed	Gene-based Therapy in a Mouse Model of Blue Cone Monochromacy.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	28751656
Pubmed	Circadian Regulation of the Rod Contribution to Mesopic Vision in Mice.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	36216501
Pubmed	Rescue of M-cone Function in Aged Opn1mw-/- Mice, a Model for Late-Stage Blue Cone Monochromacy.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	31469404
Pubmed	The molecular genetics and evolution of red and green color vision in vertebrates.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	11545071
Pubmed	Mechanisms of spectral tuning in the mouse green cone pigment.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	9238068
Pubmed	Emergence of novel color vision in mice engineered to express a human cone photopigment.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	17379811
Pubmed	Spectral tuning of a circadian photopigment in a subterranean 'blind' mammal (Spalax ehrenbergi).	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	10567724
Pubmed	Extensive cone-dependent spectral opponency within a discrete zone of the lateral geniculate nucleus supporting mouse color vision.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	34111401
Pubmed	Plasmalemmal and vesicular gamma-aminobutyric acid transporter expression in the developing mouse retina.	SLC6A1 SLC32A1	5.83e-06	3	49	2	18975268
Pubmed	Co-expression of murine opsins facilitates identifying the site of cone adaptation.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	12511072
Pubmed	The Pem homeobox gene is X-linked and exclusively expressed in extraembryonic tissues during early murine development.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	7958444
Pubmed	Genetically engineered mice with an additional class of cone photoreceptors: implications for the evolution of color vision.	OPN1MW2 OPN1MW3	5.83e-06	3	49	2	14500905
Pubmed	Chromatin Remodeling Enzyme Snf2h Is Essential for Retinal Cell Proliferation and Photoreceptor Maintenance.	OPN1MW2 OPN1MW3 ATM	1.04e-05	30	49	3	37048108
Pubmed	Melanopsin-driven increases in maintained activity enhance thalamic visual response reliability across a simulated dawn.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	26438865
Pubmed	Characteristic development of the GABA-removal system in the mouse spinal cord.	SLC6A1 SLC32A1	1.16e-05	4	49	2	24412234
Pubmed	Light/dark translocation of alphatransducin in mouse photoreceptor cells expressing G90D mutant opsin.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	17249565
Pubmed	Structural and functional rescue of cones carrying the most common cone opsin C203R missense mutation.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	38060327
Pubmed	Contribution of M-opsin-based color vision to refractive development in mice.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	34126082
Pubmed	Physiological features of the S- and M-cone photoreceptors of wild-type mice from single-cell recordings.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	16567464
Pubmed	Visual responses in the dorsal lateral geniculate nucleus at early stages of retinal degeneration in rd1 PDE6β mice.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	31461375
Pubmed	S-opsin knockout mice with the endogenous M-opsin gene replaced by an L-opsin variant.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	24801621
Pubmed	Murine and bovine blue cone pigment genes: cloning and characterization of two new members of the S family of visual pigments.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	8088841
Pubmed	Modulation of Fast Narrowband Oscillations in the Mouse Retina and dLGN According to Background Light Intensity.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	28103478
Pubmed	Melanopsin Contributions to the Representation of Images in the Early Visual System.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	28528909
Pubmed	Molecular biology of the visual pigments.	OPN1MW2 OPN1MW	1.16e-05	4	49	2	3303660
Pubmed	Cones Support Alignment to an Inconsistent World by Suppressing Mouse Circadian Responses to the Blue Colors Associated with Twilight.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	31846668
Pubmed	Melanopsin-driven light adaptation in mouse vision.	OPN1MW2 OPN1MW3	1.16e-05	4	49	2	25308073
Pubmed	Noncoding Mutations in a Thyroid Hormone Receptor Gene That Impair Cone Photoreceptor Function.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	36631163
Pubmed	Using Silent Substitution to Track the Mesopic Transition From Rod- to Cone-Based Vision in Mice.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	26818794
Pubmed	A common integration locus in type B retrovirus-induced thymic lymphomas.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	1333116
Pubmed	Melanopsin-based brightness discrimination in mice and humans.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	22633808
Pubmed	The murine cone photoreceptor: a single cone type expresses both S and M opsins with retinal spatial patterning.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	11055434
Pubmed	A distinct contribution of short-wavelength-sensitive cones to light-evoked activity in the mouse pretectal olivary nucleus.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	22090509
Pubmed	Comparative sequence analysis of the MECP2-locus in human and mouse reveals new transcribed regions.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	10723722
Pubmed	Enhancer/promoter activities of the long/middle wavelength-sensitive opsins of vertebrates mediated by thyroid hormone receptor β2 and COUP-TFII.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	24058409
Pubmed	Variations in photoreceptor throughput to mouse visual cortex and the unique effects on tuning.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	34099749
Pubmed	Peripherin-2 differentially interacts with cone opsins in outer segments of cone photoreceptors.	OPN1MW2 OPN1MW3	1.94e-05	5	49	2	27033727
Pubmed	Functional comparison of rod and cone Gα(t) on the regulation of light sensitivity.	OPN1MW2 OPN1MW3	2.91e-05	6	49	2	23288843
Pubmed	Reduced levels of dystrophin associated proteins in the brains of mice deficient for Dp71.	OPN1MW2 OPN1MW3	2.91e-05	6	49	2	8872469
Pubmed	A thyroid hormone receptor that is required for the development of green cone photoreceptors.	OPN1MW2 OPN1MW3	2.91e-05	6	49	2	11138006
Pubmed	GRK1-dependent phosphorylation of S and M opsins and their binding to cone arrestin during cone phototransduction in the mouse retina.	OPN1MW2 OPN1MW	2.91e-05	6	49	2	12853434
Pubmed	Impaired cytokine signaling in mice lacking the IL-1 receptor-associated kinase.	OPN1MW2 OPN1MW3	2.91e-05	6	49	2	10395695
Pubmed	Transient expression of thyroid hormone nuclear receptor TRbeta2 sets S opsin patterning during cone photoreceptor genesis.	OPN1MW2 OPN1MW3	2.91e-05	6	49	2	17436273
Pubmed	Telomere-related markers for the pseudoautosomal region of the mouse genome.	OPN1MW2 OPN1MW3	2.91e-05	6	49	2	1549575
Pubmed	Expression of the suppressor of cytokine signaling-5 (SOCS5) negatively regulates IL-4-dependent STAT6 activation and Th2 differentiation.	SOCS5 IL4R	2.91e-05	6	49	2	12242343
Pubmed	Characterization of cDNAs encoding the murine interleukin 2 receptor (IL-2R) gamma chain: chromosomal mapping and tissue specificity of IL-2R gamma chain expression.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	8378320
Pubmed	Retarded developmental expression and patterning of retinal cone opsins in hypothyroid mice.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	18974269
Pubmed	Rod Photoreceptor Activation Alone Defines the Release of Dopamine in the Retina.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	30799247
Pubmed	Activation of the blue opsin gene in cone photoreceptor development by retinoid-related orphan receptor beta.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	16574740
Pubmed	Rods progressively escape saturation to drive visual responses in daylight conditions.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	29180667
Pubmed	Genetic and physical mapping of a gene encoding a methyl CpG binding protein, Mecp2, to the mouse X chromosome.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	8001979
Pubmed	NeuroD1 regulates expression of thyroid hormone receptor 2 and cone opsins in the developing mouse retina.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	18199774
Pubmed	Mapping of the murine tbl1 gene reveals a new rearrangement between mouse and human X Chromosomes.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	9880679
Pubmed	Cloning and distribution of myosin 3B in the mouse retina: differential distribution in cone outer segments.	OPN1MW2 OPN1MW3	4.07e-05	7	49	2	19332056
Pubmed	X-chromosome gene order in different Mus species crosses.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	3416629
Pubmed	The retinitis pigmentosa GTPase regulator (RPGR)- interacting protein: subserving RPGR function and participating in disk morphogenesis.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	12651948
Pubmed	Transcriptional profiling of murine retinas undergoing semi-synchronous cone photoreceptor differentiation.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	31163126
Pubmed	Type 3 deiodinase, a thyroid-hormone-inactivating enzyme, controls survival and maturation of cone photoreceptors.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	20203194
Pubmed	Tubby is required for trafficking G protein-coupled receptors to neuronal cilia.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	23351594
Pubmed	Localization of the mdx mutation within the mouse dystrophin gene.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	2903046
Pubmed	A retinitis pigmentosa GTPase regulator (RPGR)-deficient mouse model for X-linked retinitis pigmentosa (RP3).	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	10725384
Pubmed	Retinoid X receptor (gamma) is necessary to establish the S-opsin gradient in cone photoreceptors of the developing mouse retina.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	16043864
Pubmed	Nr2e3 functional domain ablation by CRISPR-Cas9D10A identifies a new isoform and generates retinitis pigmentosa and enhanced S-cone syndrome models.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	33007388
Pubmed	Genetic mapping on the mouse X chromosome of human cDNA clones for the fragile X and Hunter syndromes.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	1572654
Pubmed	Linkage of amelogenin (Amel) to the distal portion of the mouse X chromosome.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	1675194
Pubmed	Two transcription factors can direct three photoreceptor outcomes from rod precursor cells in mouse retinal development.	OPN1MW2 OPN1MW3	5.42e-05	8	49	2	21813673
Pubmed	Retinal dystrophy resulting from ablation of RXR alpha in the mouse retinal pigment epithelium.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	14742273
Pubmed	A visual circuit uses complementary mechanisms to support transient and sustained pupil constriction.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	27669145
Pubmed	Close linkage of the murine locus bare patches to the X-linked visual pigment gene: implications for mapping human X-linked dominant chondrodysplasia punctata.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	1973136
Pubmed	Feedback induction of a photoreceptor-specific isoform of retinoid-related orphan nuclear receptor β by the rod transcription factor NRL.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	25296752
Pubmed	Comparative mapping of the actin-binding protein 280 genes in human and mouse.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	8088838
Pubmed	Distinct functions of photoreceptor cell-specific nuclear receptor, thyroid hormone receptor beta2 and CRX in one photoreceptor development.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	12407160
Pubmed	ZBED4, a cone and Müller cell protein in human retina, has a different cellular expression in mouse.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	21850176
Pubmed	Top2b is involved in the formation of outer segment and synapse during late-stage photoreceptor differentiation by controlling key genes of photoreceptor transcriptional regulatory network.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	28370415
Pubmed	IFT20 is required for opsin trafficking and photoreceptor outer segment development.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	21307337
Pubmed	Multilocus molecular mapping of the mouse X chromosome.	OPN1MW2 OPN1MW3	6.96e-05	9	49	2	2906327
Pubmed	Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	21148184
Pubmed	Fam151b, the mouse homologue of C.elegans menorin gene, is essential for retinal function.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	31949211
Pubmed	Comparative mapping on the mouse and human X chromosomes of a human cDNA clone encoding the vasopressin renal-type receptor (AVP2R).	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	8449515
Pubmed	Mapping of ornithine aminotransferase gene sequences to mouse chromosomes 7, X, and 3.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	1349842
Pubmed	The nanophthalmos protein TMEM98 inhibits MYRF self-cleavage and is required for eye size specification.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	32236127
Pubmed	Physical mapping of the loci Gabra3, DXPas8, CamL1, and Rsvp in a region of the mouse X chromosome homologous to human Xq28.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	1684949
Pubmed	Mapping of the phosphorylase kinase alpha subunit gene on the mouse X chromosome.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	1973380
Pubmed	Cyclophilin-related protein RanBP2 acts as chaperone for red/green opsin.	OPN1MW2 OPN1MW	8.69e-05	10	49	2	8857542
Pubmed	Linkage of a gene for neural cell adhesion molecule, L1 (CamL1) to the Rsvp region of the mouse X chromosome.	OPN1MW2 OPN1MW3	8.69e-05	10	49	2	1964443
Pubmed	Mannose supplements induce embryonic lethality and blindness in phosphomannose isomerase hypomorphic mice.	OPN1MW2 OPN1MW3	1.06e-04	11	49	2	24421398
Pubmed	Physical linkage of the A-raf-1, properdin, synapsin I, and TIMP genes on the human and mouse X chromosomes.	OPN1MW2 OPN1MW3	1.06e-04	11	49	2	1572636
Cytoband	2q11.1	TRIM43B TRIM43	4.14e-04	28	49	2	2q11.1
Cytoband	3q25.1	MED12L TMEM14EP	5.77e-04	33	49	2	3q25.1
Cytoband	Ensembl 112 genes in cytogenetic band chr3q11	GPR15 CLDND1	1.54e-03	54	49	2	chr3q11
Cytoband	Ensembl 112 genes in cytogenetic band chrXq28	OPN1MW2 OPN1MW3 OPN1MW	1.55e-03	213	49	3	chrXq28
Cytoband	1p36.33	SLC35E2A SLC35E2B	3.10e-03	77	49	2	1p36.33
GeneFamily	Opsin receptors	OPN1MW2 OPN1MW3 OPN1MW	1.40e-06	11	38	3	215
GeneFamily	Solute carriers	SLC6A1 SLC32A1 SLC35E2A SLC44A2 SLC7A5 SLC35E2B	1.60e-04	395	38	6	752
GeneFamily	G protein-coupled receptors, Class A orphans	GPR15 GPR20 GPR132	5.84e-04	78	38	3	262
GeneFamily	Olfactory receptors, family 51	OR51B5 OR51B6	3.85e-03	44	38	2	164
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Nxph3-Excitatory_Neuron.Slc17a7.Nxph3-Ajap1_(Entorhinal_cortex)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	TRIM43 OPN1MW SOAT2	2.03e-05	49	48	3	0b3e9c8f166be5d6aab318da4b87176427637877
ToppCell	primary_visual_cortex-Neuronal-GABAergic_neuron-Sst-Sst_Myh8_Fibin\|primary_visual_cortex / Per Region, Lineage, Cell class, Cell type, Cell subtype	SLC6A1 SLC32A1 ADGRG1 IL4R	2.46e-05	157	48	4	741d79c10cb87fa7f14080c6fccb1553c3a20bad
ToppCell	COPD-Myeloid-pDC\|World / Disease state, Lineage and Cell class	SLC32A1 BRF1 MED12L SLC7A5	3.68e-05	174	48	4	be8227398300711ccda5ecc41ad34064bb246b19
ToppCell	Mid-temporal_gyrus_(MTG)-Neuronal-Glutamatergic_Excit-Glut_A_(CT)-Glut_CT_L6_FEZF2-Exc_L6_FEZF2_CPZ\|Mid-temporal_gyrus_(MTG) / Sample groups (6 Anatomical region groups), with 5 level hierarchy of cell types	TRIM43B OR51B5 OR51B6 TRIM43	4.20e-05	180	48	4	a499548391e6833b78f6e920f8e32a755814a9da
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-nan\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC4AP TM9SF3 SLC44A2 MED12L	5.08e-05	189	48	4	6dd4ec5ce4beb856f0d2d1654e3c4676d1d63736
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC4AP TM9SF3 SLC44A2 MED12L	5.08e-05	189	48	4	3ae479ec7e00c57127cbe51a398329b10ca9848c
ToppCell	facs-Brain_Myeloid-Striatum-3m-Myeloid-microglial_cell\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC4AP TM9SF3 SLC44A2 MED12L	5.08e-05	189	48	4	875df61ee48baa5142ba4d2427bdec1c53e5a828
ToppCell	facs-Brain_Myeloid-Striatum-3m\|Brain_Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TRPC4AP TM9SF3 SLC44A2 MED12L	5.08e-05	189	48	4	97ef5215d841ff366a3e3682cd9bd04100cbfde0
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD2 TM9SF3 ATP10B GPA33	5.73e-05	195	48	4	c5f33b420c9ac14dc67fea632b8c2bc2442cbf3d
ToppCell	kidney_cells-Adult_normal_reference-Epithelial-Distal_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA ADGRG1 SLC7A5 SHISA3	5.73e-05	195	48	4	3123e02d2894c83962ba402085b5e6422ebf8c73
ToppCell	3'-Pediatric_IBD-SmallIntestine-Epithelial-goblet-Goblet_cell\|Pediatric_IBD / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ABHD2 TM9SF3 ATP10B GPA33	5.73e-05	195	48	4	219c5d0cde7f6082755154f54db221413ec555cb
ToppCell	kidney_cells-Hypertensive_with+without-CKD-Epithelial-Distal_tubule_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CLCNKA ADGRG1 SLC7A5 SHISA3	6.08e-05	198	48	4	688b0eb5534dde40b8630ab8a3252c816711e02e
ToppCell	Smart-start-Cell-Wel_seq-Non-neoplastic-Glial-Neuronal-OPC-OPC-G\|Smart-start-Cell-Wel_seq / Platform, Oncotype, Lineage, Cell_class, celltype (level4), mutation group	SLC6A1 ABHD2 ATP10B CDH18	6.20e-05	199	48	4	19a97e27a4758e794ce7246d295e112b47931a48
ToppCell	Fetal_brain-fetalBrain_Zhong_nature-GW23\|fetalBrain_Zhong_nature / Sample Type, Dataset, Time_group, and Cell type.	SLC6A1 SLC32A1 SPAAR SLC35E2B	6.20e-05	199	48	4	f30e9d3d095a1e12d759debe27540aad32861db6
Disease	blue cone monochromacy (implicated_via_orthology)	OPN1MW2 OPN1MW3 OPN1MW	1.32e-08	4	45	3	DOID:0050679 (implicated_via_orthology)
Disease	fetal hemoglobin measurement	OR51B5 OR51B6	4.69e-04	21	45	2	EFO_0004576
Disease	lung squamous cell carcinoma (is_implicated_in)	SLC7A5 ATM	6.14e-04	24	45	2	DOID:3907 (is_implicated_in)
Disease	pulse pressure measurement, diastolic blood pressure, systolic blood pressure, hypertension	GPR20 CDH18	1.31e-03	35	45	2	EFO_0000537, EFO_0005763, EFO_0006335, EFO_0006336
Disease	Anorectal Malformations	RFX6 CDH18	1.80e-03	41	45	2	C3495676

Protein segments in the cluster

Peptide	Gene	Start	Entry
VSVIYCSGTDRLCAC	BIRC6	941	Q9NR09
KVLCCVSVCQGYSAL	ABHD2	226	P08910
VPLLSIVTCYCCIAR	GPR15	206	P49685
CSILFLTCICVDRYL	GPR20	136	Q99678
LELTQYCRSVLCCRS	ATP10B	1016	O94823
TCCITPLSIIVLCYL	OPN1MW3	226	P0DN78
NYIVCEGVCLPRCIL	RFX6	131	Q8HWS3
TCCITPLSIIVLCYL	OPN1MW2	226	P0DN77
LCISYLKSETCGCRI	MKKS	126	Q9NPJ1
TTGLCVCIVAVLRRY	MED12L	876	Q86YW9
VAALIIIGIIIYCCC	GPA33	246	Q99795
CIVCKRSYVCLTSLR	ZBTB33	496	Q86T24
GVCYAFSCLVCIVVS	OR14K1	201	Q8NGZ2
LITCVSHICCVLVFY	OR51B5	236	Q9H339
SHICCILVFYVTVVC	OR51B6	241	Q9H340
CLCVLLLTAVNCYSV	SLC7A5	176	Q01650
LCTSVIFLGCCIVIL	MANSC4	291	A6NHS7
YARCIAVCSLGVWIC	RALGAPA2	1156	Q2PPJ7
TCCITPLSIIVLCYL	OPN1MW	226	P04001
VRCSRLLVGVLGCYC	ATM	716	Q13315
CIVILAVCLLCYVSI	IL4R	241	P24394
LACLVTIAAYLCSRV	ADGRG1	416	Q9Y653
PVLVCLCFVQRCYGT	CDH18	11	Q13634
YCRQASCVSLLCRPV	KRTAP10-9	261	P60411
IYNRGCTDIICCVFL	SLC44A2	26	Q8IWA5
AVCIVLTICELCYLI	GJB3	196	O75712
TRVCACLAIGCYVIG	OR5B17	136	Q8NGF7
IYVSILFLCCISCDR	GPR132	126	Q9UNW8
VLFVVTVAITCVLCC	SPAAR	26	A0A1B0GVQ0
VICLNYLVDPVTICC	TRIM43	16	Q96BQ3
LLCCVLTSVGATCCY	TMEM41A	106	Q96HV5
VYRDSIIVCCINSCT	SLC6A1	316	P30531
ICVLVGVFICSICVK	SEMA3C	6	Q99985
CLSILYNTCVCTEGV	TRPC4AP	166	Q8TEL6
PFSLQYICRAVICRC	SOCS5	481	O75159
ILGSVVAIYCCTCLR	SHISA3	111	A0PJX4
TVIGCVKTLVPCCLY	SLC35E2A	116	P0CK97
FVGTCCLRLLRVYTC	MYCBP2	1461	O75592
KVLYSCCLVSEGLCR	STK36	716	Q9NRP7
GCVLYACFILGRLCV	SOAT2	306	O75908
LIGLCACICRSLYPT	CLDND1	156	Q9NY35
ICGVLSCAYLFCQRT	CLCNKA	291	P51800
CEFVGTLVCRCQYIL	STAG3L4	51	Q8TBR4
TVIGCVKTLVPCCLY	SLC35E2B	116	P0CK96
VIAACLYLVCRTEGT	BRF1	131	Q92994
LCIVTVCVTIVCTYF	TM9SF3	491	Q9HD45
VICLNYLVDPVTICC	TRIM43B	16	A6NCK2
AVVCCYTGKILIACL	SLC32A1	156	Q9H598
NIYACGFSCRCLLIV	TMEM14EP	86	Q6UXP3