Cluster composition

Functions

Category	Name	IntersectionWithQuery	PValue	GenesInTerm	GenesInQuery	GenesInTermInQuery	ID
GeneOntologyBiologicalProcess	regulation of GTPase activity	CCDC125 SEMA4D MYO9A RTN4R APC2 RAPGEF1 ARHGEF15 TGM2 TBC1D10B RASA4 RAB3GAP2 FGD1 RASA4B	6.41e-06	335	176	13	GO:0043087
MousePheno	ventricular septal defect	BICRA HIC2 CHD7 MORC2 GDF1 TRIP11 SIRT1 EHBP1L1 VCAN SMARCA4 CPLANE1 NOS3 SMAD6	3.21e-06	261	145	13	MP:0010402
MousePheno	muscular ventricular septal defect	HIC2 MORC2 TRIP11 SMARCA4 CPLANE1 NOS3 SMAD6	1.47e-05	77	145	7	MP:0010420
MousePheno	abnormal interventricular septum muscular part morphology	HIC2 MORC2 TRIP11 SMARCA4 CPLANE1 NOS3 SMAD6	1.74e-05	79	145	7	MP:0010498
MousePheno	abnormal interventricular septum morphology	BICRA HIC2 CHD7 MORC2 GDF1 TRIP11 SIRT1 EHBP1L1 VCAN SMARCA4 CPLANE1 NOS3 SMAD6	5.67e-05	342	145	13	MP:0000281
Pubmed	Large-scale characterization of HeLa cell nuclear phosphoproteins.	SEC16B WASHC2C HIRIP3 DIDO1 CHD7 MORC2 TERF2 TRRAP SIRT1 PITPNM1 KANSL3 TBC1D10B SAFB MDC1 HELZ2 SAFB2 SMARCA4 KDM2B SAC3D1 TACC3 SRRM2 DDX24 TOP2B	1.57e-11	774	179	23	15302935
Pubmed	PRISMA and BioID disclose a motifs-based interactome of the intrinsically disordered transcription factor C/EBPα.	IRF2BP1 BICRA DIDO1 CHD7 MORC2 TRRAP SIRT1 KANSL3 CCNT1 RCOR1 TNRC18 MAP7D1 SAFB SND1 RAB3GAP2 SAFB2 SMARCA4 USP39 SRRM2 CDCA5 FUBP3 HOMER3 TOP2B	1.42e-08	1103	179	23	34189442
Pubmed	A central chaperone-like role for 14-3-3 proteins in human cells.	CARMIL2 CAMKK1 MYO9A EXPH5 PLEKHG2 LARP1B TRIP11 TBC1D10B MAP7D1 MAST4 SYNJ2 TESK2 RAB3GAP2 NHS CRYBG3 CTNND1 SRRM2 PLEKHA7 DCLK1 WNK3	2.32e-08	861	179	20	36931259
Pubmed	The cell proliferation antigen Ki-67 organises heterochromatin.	IRF2BP1 DIDO1 CHD7 TERF2 TRRAP CCNT1 RCOR1 MAP7D1 TFB2M USP39 MGA DDX24 FUBP3 DCLK1	3.26e-08	410	179	14	26949251
Pubmed	Synthetic Lethal and Resistance Interactions with BET Bromodomain Inhibitors in Triple-Negative Breast Cancer.	IRF2BP1 DIDO1 MORC2 TRRAP SIRT1 KANSL3 CCNT1 FARSA RCOR1 SAFB UBE2A SND1 FAM50A MDC1 SAFB2 SMARCA4 USP39 CTNND1 FUBP3 TOP2B	3.22e-07	1014	179	20	32416067
Pubmed	Systematic bromodomain protein screens identify homologous recombination and R-loop suppression pathways involved in genome integrity.	CERK LPCAT1 RIBC2 BICRA SH3BP2 GPT HIC2 TRRAP SIRT1 CCNT1 TBC1D10B RCOR1 MAP7D1 ZNF608 PCDH19 SCN5A SMARCA4 CRYBG3 SRRM2 MGA DDX24	3.45e-07	1116	179	21	31753913
Pubmed	A probability-based approach for high-throughput protein phosphorylation analysis and site localization.	WASHC2C HIRIP3 TRMT1 DIDO1 MORC2 ANKLE2 TERF2 SIRT1 SAFB NHS TACC3 SRRM2 DDX24 CDCA5	3.93e-07	503	179	14	16964243
Pubmed	The in vivo Interaction Landscape of Histones H3.1 and H3.3.	HIRIP3 DIDO1 CHD7 MORC2 TRRAP SIRT1 CCNT1 FAM50A MDC1 SMARCA4 KDM2B USP39 MGA DDX24 TOP2B	6.84e-07	608	179	15	36089195
Pubmed	A dual-activity topoisomerase complex regulates mRNA translation and turnover.	BICRA TRMT1 RAPGEF1 WASHC2A TRRAP GGT7 KANSL3 TNRC18 SLC38A10 EHBP1L1 EFNA2 MROH1 SND1 PTPRS NISCH SCN5A HELZ2 SAC3D1 SOWAHB TBCD	1.22e-06	1105	179	20	35748872
Pubmed	Human transcription factor protein interaction networks.	ASXL1 ACACB IRF2BP1 BICRA ETV4 DIDO1 HIC2 CHD7 MORC2 WASHC2A TRRAP SIRT1 KANSL3 RCOR1 MAP7D1 ZNF608 MDC1 SMARCA4 KDM2B SRRM2 MGA DDX24 FUBP3	1.37e-06	1429	179	23	35140242
Pubmed	KCTD13-mediated ubiquitination and degradation of GluN1 regulates excitatory synaptic transmission and seizure susceptibility.	CARMIL2 MYO9A PPP1R12B SPTB HDHD2 TRIP11 PNMA8B PITPNM1 FARSA HSPA12A MAP7D1 SAFB SND1 PTPRS CRACDL NISCH VCAN SMARCA4 CTNND1 PLEKHA7 HOMER3 DCLK1 GOT1	1.40e-06	1431	179	23	37142655
Pubmed	Proximity-dependent Mapping of the Androgen Receptor Identifies Kruppel-like Factor 4 as a Functional Partner.	CHD7 KANSL3 CCNT1 RCOR1 TNRC18 ZNF608 MDC1 SMARCA4 KDM2B MGA	1.44e-06	268	179	10	33640491
Pubmed	HSF1 phosphorylation establishes an active chromatin state via the TRRAP-TIP60 complex and promotes tumorigenesis.	EMC6 HIRIP3 IRF2BP1 DIDO1 MORC2 TRRAP TRIP11 ARHGEF15 MDC1 SAFB2 SMARCA4 KDM2B CACNA1G TFB2M MGA DDX24	2.05e-06	754	179	16	35906200
Pubmed	A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.	ACACB APBB2 ANKLE2 TRIP11 TBC1D10B HSPA12A NISCH PCDH19 NHS CTNND1 PALS2 PLEKHA7	2.13e-06	421	179	12	36976175
Pubmed	Interaction network of human early embryonic transcription factors.	ACACB BICRA CHD7 SIRT1 RCOR1 TNRC18 ZNF608 MDC1 SMARCA4 KDM2B MGA	2.32e-06	351	179	11	38297188
Pubmed	Spatiotemporal profile of postsynaptic interactomes integrates components of complex brain disorders.	APC2 DIDO1 CHD7 TRIP11 EPM2AIP1 FARSA RCOR1 MAP7D1 PTPRS NISCH SAFB2 SMARCA4 CTNND1 TACC3 MGA HOMER3 DCLK1 WNK3	2.75e-06	963	179	18	28671696
Pubmed	Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.	ASXL1 HIC2 CHD7 ARHGEF15 ZNF608 RAB3GAP2 HELZ2 PHLPP1 CACNA1G	2.77e-06	225	179	9	12168954
Pubmed	MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.	ZBTB38 DIDO1 HIC2 CHD7 USP9Y TRRAP TBC1D10B FARSA EHBP1L1 SAFB VCAN HELZ2 SAFB2 SMARCA4 USP39 SRRM2 DDX24 PIK3R5 TOP2B	3.54e-06	1082	179	19	38697112
Pubmed	Proteomic analysis of steady-state nuclear hormone receptor coactivator complexes.	MORC2 TRIP11 SND1 MDC1 SRRM2 DDX24	5.34e-06	85	179	6	16051665
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: I. The complete nucleotide sequences of 100 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	HSPA12A RCOR1 PHLPP1 CTNND1 DCLK1 TBCD	6.11e-06	87	179	6	12465718
Pubmed	A novel role for the peptidyl-prolyl cis-trans isomerase Cyclophilin A in DNA-repair following replication fork stalling via the MRE11-RAD50-NBS1 complex.	DIDO1 WASHC2A DNAJC2 KANSL3 SAFB FAM50A RAB3GAP2 CRYBG3 CTNND1 TACC3 SRRM2 FUBP3	6.83e-06	472	179	12	38943005
Pubmed	Mouse screen reveals multiple new genes underlying mouse and human hearing loss.	SEC16B ASXL1 WASHC2C MYO9A SKIDA1 CHD7 ANKRD6 UBASH3A CCDC57 WASHC2A TRRAP PITPNM1 FARSA SLC38A10 EHBP1L1 SYNJ2 CRACDL CCDC106 MRAP2 DCLK1	6.99e-06	1242	179	20	30973865
Pubmed	H4K20me0 recognition by BRCA1-BARD1 directs homologous recombination to sister chromatids.	HIRIP3 DIDO1 CHD7 TERF2 TRRAP KANSL3 RCOR1 MAP7D1 SAFB MDC1 SAFB2 SMARCA4 KDM2B USP39 SRRM2 MGA DDX24 CDCA5 FUBP3 TOP2B	1.27e-05	1294	179	20	30804502
Pubmed	Prediction of the coding sequences of unidentified human genes. VII. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.	DIDO1 MAST4 SYNJ2 CTNND1 SRRM2 DCLK1	1.71e-05	104	179	6	9205841
Pubmed	The DNA sequence and biology of human chromosome 19.	TRMT1 GDF1 FARSA SAFB EFNA2 PTPRS SAFB2 SMARCA4 HOMER3	1.80e-05	284	179	9	15057824
Pubmed	The Interleukin-2-mTORc1 Kinase Axis Defines the Signaling, Differentiation, and Metabolism of T Helper 1 and Follicular B Helper T Cells.	PDCD1 HLA-DQB2 KATNB1 LFNG RASA4 RASA4B CDCA5 PIK3R5	2.49e-05	227	179	8	26410627
Pubmed	Role of SIRT1 and FOXO factors in eNOS transcriptional activation by resveratrol.	SIRT1 NOS3	2.63e-05	2	179	2	23583951
Pubmed	Salvianolic acid inhibits the effects of high glucose on vascular endothelial dysfunction by modulating the Sirt1-eNOS pathway.	SIRT1 NOS3	2.63e-05	2	179	2	30431688
Pubmed	Scaffold attachment factors SAFB1 and SAFB2: Innocent bystanders or critical players in breast tumorigenesis?	SAFB SAFB2	2.63e-05	2	179	2	14587024
Pubmed	The ubiquitin-conjugating DNA repair enzyme HR6A is a maternal factor essential for early embryonic development in mice.	UBE2A UBE2B	2.63e-05	2	179	2	15169909
Pubmed	Abnormalities in aminotransferase levels during acute pyelonephritis.	GPT GOT1	2.63e-05	2	179	2	19393479
Pubmed	Loss of HR6B ubiquitin-conjugating activity results in damaged synaptonemal complex structure and increased crossing-over frequency during the male meiotic prophase.	UBE2A UBE2B	2.63e-05	2	179	2	12556476
Pubmed	CAPRI regulates Ca(2+)-dependent inactivation of the Ras-MAPK pathway.	RASA4 RASA4B	2.63e-05	2	179	2	11448776
Pubmed	Non-alcoholic steatohepatitis with normal aminotransferase values.	GPT GOT1	2.63e-05	2	179	2	19370784
Pubmed	Structural and functional conservation of two human homologs of the yeast DNA repair gene RAD6.	UBE2A UBE2B	2.63e-05	2	179	2	1717990
Pubmed	alpha1G-dependent T-type Ca2+ current antagonizes cardiac hypertrophy through a NOS3-dependent mechanism in mice.	CACNA1G NOS3	2.63e-05	2	179	2	19920353
Pubmed	Sirtuin 1 regulates cardiac electrical activity by deacetylating the cardiac sodium channel.	SIRT1 SCN5A	2.63e-05	2	179	2	28191886
Pubmed	Localization of two human homologs, HHR6A and HHR6B, of the yeast DNA repair gene RAD6 to chromosomes Xq24-q25 and 5q23-q31.	UBE2A UBE2B	2.63e-05	2	179	2	1559696
Pubmed	Increased tissue transglutaminase activity contributes to central vascular stiffness in eNOS knockout mice.	TGM2 NOS3	2.63e-05	2	179	2	23873798
Pubmed	Efficacy of statins on sirtuin 1 and endothelial nitric oxide synthase expression: the role of sirtuin 1 gene variants in human coronary atherosclerosis.	SIRT1 NOS3	2.63e-05	2	179	2	25582759
Pubmed	Control of HIV replication in astrocytes by a family of highly conserved host proteins with a common Rev-interacting domain (Risp).	WASHC2C WASHC2A	2.63e-05	2	179	2	20827171
Pubmed	The NMR structure of the class I human ubiquitin-conjugating enzyme 2b.	UBE2A UBE2B	2.63e-05	2	179	2	11885984
Pubmed	Shear stress, SIRT1, and vascular homeostasis.	SIRT1 NOS3	2.63e-05	2	179	2	20479254
Pubmed	HIC2, a new transcription activator of SIRT1.	HIC2 SIRT1	2.63e-05	2	179	2	31127867
Pubmed	FAM21 is critical for TLR2/CLEC4E-mediated dendritic cell function against Candida albicans.	WASHC2C WASHC2A	2.63e-05	2	179	2	36717248
Pubmed	[The expression of P120 catenin in pancreatic carcinoma and the relationship between the T755G polymorphism of P120 catenin gene and pancreatic carcinoma].	CTNND1 PLEKHA7	2.63e-05	2	179	2	20193553
Pubmed	Typing classical polymorphisms by real-time PCR: analysis of the GPT and ALAD protein polymorphisms in the Jewish populations.	GPT ALAD	2.63e-05	2	179	2	18432999
Pubmed	Early abnormal liver enzyme levels may increase the prevalence of human cytomegalovirus antigenaemia after hematopoietic stem cell transplantation.	GPT GOT1	2.63e-05	2	179	2	28415934
Pubmed	KDM2B is a histone H3K79 demethylase and induces transcriptional repression via sirtuin-1-mediated chromatin silencing.	SIRT1 KDM2B	2.63e-05	2	179	2	29763382
Pubmed	Association between Endothelial nitric oxide synthase and Hepatic lipase gene polymorphisms with the risk of coronary artery disease in Southern Iran population - A case control study.	LIPC NOS3	2.63e-05	2	179	2	33673789
Pubmed	Insulin resistance and ferritin as major determinants of abnormal serum aminotransferase in severely obese children.	GPT GOT1	2.63e-05	2	179	2	17907318
Pubmed	Alternative Splicing of RAD6B and Not RAD6A is Selectively Increased in Melanoma: Identification and Functional Characterization.	UBE2A UBE2B	2.63e-05	2	179	2	31683936
Pubmed	Regulation of KDM2B and Brg1 on Inflammatory Response of Nasal Mucosa in CRSwNP.	SMARCA4 KDM2B	2.63e-05	2	179	2	31041569
Pubmed	Secreted CLIC3 drives cancer progression through its glutathione-dependent oxidoreductase activity.	CLIC3 TGM2	2.63e-05	2	179	2	28198360
Pubmed	Elevated aspartate and alanine aminotransferase levels and natural death among patients with methamphetamine dependence.	GPT GOT1	2.63e-05	2	179	2	22242166
Pubmed	Scaffold attachment factor B (SAFB)1 and SAFB2 cooperatively inhibit the intranuclear mobility and function of ERα.	SAFB SAFB2	2.63e-05	2	179	2	22566185
Pubmed	Testosterone deficiency accelerates neuronal and vascular aging of SAMP8 mice: protective role of eNOS and SIRT1.	SIRT1 NOS3	2.63e-05	2	179	2	22238626
Pubmed	RAD6 promotes DNA repair and stem cell signaling in ovarian cancer and is a promising therapeutic target to prevent and treat acquired chemoresistance.	UBE2A UBE2B	2.63e-05	2	179	2	28806395
Pubmed	Sequential changes of serum aminotransferase levels in patients with severe acute respiratory syndrome.	GPT GOT1	2.63e-05	2	179	2	15306699
Pubmed	Identification of a novel Rev-interacting cellular protein.	WASHC2C WASHC2A	2.63e-05	2	179	2	15847701
Pubmed	SAFB1 mediates repression of immune regulators and apoptotic genes in breast cancer cells.	SAFB SAFB2	2.63e-05	2	179	2	19901029
Pubmed	PD-1 and CD103 Are Widely Coexpressed on Prognostically Favorable Intraepithelial CD8 T Cells in Human Ovarian Cancer.	PDCD1 ITGAE	2.63e-05	2	179	2	25957117
Pubmed	Effect of statins on sirtuin 1 and endothelial nitric oxide synthase expression in young patients with a history of premature myocardial infarction.	SIRT1 NOS3	2.63e-05	2	179	2	29664427
Pubmed	Neither ischemic parenchymal volume nor severe grade complication correlate transient high transaminase elevation after liver resection.	GPT GOT1	2.63e-05	2	179	2	29553104
Pubmed	Clinical implications of aminotransferase elevation in hospitalised infants aged 8-90 days with respiratory virus detection.	GPT GOT1	2.63e-05	2	179	2	32157800
Pubmed	Correlations of Complete Blood Count with Alanine and Aspartate Transaminase in Chinese Subjects and Prediction Based on Back-Propagation Artificial Neural Network (BP-ANN).	GPT GOT1	2.63e-05	2	179	2	28628604
Pubmed	Reference intervals for total bilirubin, ALT, AST and creatinine in healthy Chinese elderly.	GPT GOT1	2.63e-05	2	179	2	25272068
Pubmed	Insm1 Induces Neural Progenitor Delamination in Developing Neocortex via Downregulation of the Adherens Junction Belt-Specific Protein Plekha7.	INSM1 PLEKHA7	2.63e-05	2	179	2	29503187
Pubmed	No germline mutations in supposed tumour suppressor genes SAFB1 and SAFB2 in familial breast cancer with linkage to 19p.	SAFB SAFB2	2.63e-05	2	179	2	19077293
Pubmed	Low SAFB levels are associated with worse outcome in breast cancer patients.	SAFB SAFB2	2.63e-05	2	179	2	19137425
Pubmed	A comparative study of glutamate oxaloacetate transaminase (GOT) and glutamate pyruvate transaminase (GPT) levels in the saliva of diabetic and normal patients.	GPT GOT1	2.63e-05	2	179	2	24849491
Pubmed	Effect of SWI/SNF chromatin remodeling complex on HIV-1 Tat activated transcription.	CCNT1 SMARCA4	2.63e-05	2	179	2	16893449
Pubmed	SIRT1 promotes endothelium-dependent vascular relaxation by activating endothelial nitric oxide synthase.	SIRT1 NOS3	2.63e-05	2	179	2	17785417
Pubmed	Silent information regulator 2 homolog 1 counters cerebral hypoperfusion injury by deacetylating endothelial nitric oxide synthase.	SIRT1 NOS3	2.63e-05	2	179	2	25213338
Pubmed	Role of the programmed death-1 pathway in regulation of alloimmune responses in vivo.	PDCD1 HLA-DQB2	2.63e-05	2	179	2	15749874
Pubmed	An essential function for the calcium-promoted Ras inactivator in Fcgamma receptor-mediated phagocytosis.	RASA4 RASA4B	2.63e-05	2	179	2	16041389
Pubmed	Human colorectal cancer: upregulation of the adaptor protein Rai in TILs leads to cell dysfunction by sustaining GSK-3 activation and PD-1 expression.	PDCD1 GDF1	2.63e-05	2	179	2	38175205
Pubmed	Silent information regulator 1 (SIRT1) promotes the migration and proliferation of endothelial progenitor cells through the PI3K/Akt/eNOS signaling pathway.	SIRT1 NOS3	2.63e-05	2	179	2	26045735
Pubmed	Aspartate aminotransferase to alanine aminotransferase ratio is associated with frailty and mortality in older patients with heart failure.	GPT GOT1	2.63e-05	2	179	2	34099767
Pubmed	Unravelling the RNA-Binding Properties of SAFB Proteins in Breast Cancer Cells.	SAFB SAFB2	2.63e-05	2	179	2	26273616
Pubmed	Sex Differences in the Association Between AST/ALT and Incidence of Type 2 Diabetes in Japanese Patients with Nonalcoholic Fatty Liver Disease: A Retrospective Cohort Study.	GPT GOT1	2.63e-05	2	179	2	37752709
Pubmed	Scaffold attachment factor B2 (SAFB2)-null mice reveal non-redundant functions of SAFB2 compared with its paralog, SAFB1.	SAFB SAFB2	2.63e-05	2	179	2	26092125
Pubmed	USP7 targets XIAP for cancer progression: Establishment of a p53-independent therapeutic avenue for glioma.	ACACB FAM186A MDC1 SMARCA4 UMPS SRRM2 DDX24 TOP2B	3.10e-05	234	179	8	36243803
Pubmed	Systematic analysis of human protein complexes identifies chromosome segregation proteins.	ASXL1 WASHC2C PPP1R12B WASHC2A TERF2 SIRT1 KANSL3 RCOR1 MAP7D1 SYNJ2 SMARCA4 PYGM USP39 TACC3 CDCA5 HOMER3 TOP2B TBCD	3.17e-05	1155	179	18	20360068
Pubmed	Proteomic analyses reveal distinct chromatin-associated and soluble transcription factor complexes.	ASXL1 FOXN2 HIC2 MORC2 TRRAP KANSL3 MAP7D1 NISCH SMARCA4 CTNND1 MGA DDX24 FUBP3 TOP2B FOXD4	4.09e-05	857	179	15	25609649
Pubmed	Novel protein interactions with endoglin and activin receptor-like kinase 1: potential role in vascular networks.	KATNB1 UBE2B RASA4 RASA4B USP39 NOS3	5.05e-05	126	179	6	24319055
Pubmed	Combinatorial CRISPR screen identifies fitness effects of gene paralogues.	LARP1B CCNT1 FAM50A PTPRS SMARCA4 SRRM2 HOMER3	5.35e-05	186	179	7	33637726
Pubmed	Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.	ASXL1 WASHC2C WASHC2A EPM2AIP1 MAP7D1 MROH1 NISCH PCDH19 RAB3GAP2 SRRM2	5.38e-05	407	179	10	12693553
Pubmed	Identification of SUMO Binding Proteins Enriched after Covalent Photo-Cross-Linking.	WASHC2C DIDO1 SAFB SND1 MDC1 SAFB2 SMARCA4 UMPS SRRM2	6.05e-05	332	179	9	32786267
Pubmed	Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation.	WASHC2C SPTB RAPGEF1 DIDO1 HIC2 WASHC2A TNRC18 SAFB MROH1 ZNF608 PTPRS VCAN CPXM1 CTNND1 PLEKHA7 CDCA5 HOMER3 SMAD6	6.08e-05	1215	179	18	15146197
Pubmed	Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes.	TRRAP SMARCA4 SRRM2 TOP2B	6.52e-05	42	179	4	35705031
Pubmed	Proximity-dependent biotin identification (BioID) reveals a dynamic LSD1-CoREST interactome during embryonic stem cell differentiation.	ACACB CHD7 RCOR1 MAP7D1 ZNF608 RAB3GAP2 KDM2B CRYBG3 TACC3 MGA	6.72e-05	418	179	10	34709266
Pubmed	Defining the human deubiquitinating enzyme interaction landscape.	ASXL1 TCEAL2 TRRAP SIRT1 SHQ1 FARSA MAP7D1 SAFB SND1 PHLPP1 UMPS USP39 CTNND1 SRRM2 DDX24 PLEKHA7	6.92e-05	1005	179	16	19615732
Pubmed	RNF43 inhibits WNT5A-driven signaling and suppresses melanoma invasion and resistance to the targeted therapy.	EXPH5 ANKLE2 TRIP11 NHS CRYBG3 CTNND1 PLEKHA7 FUBP3	7.05e-05	263	179	8	34702444
Pubmed	Identification of the SOX2 Interactome by BioID Reveals EP300 as a Mediator of SOX2-dependent Squamous Differentiation and Lung Squamous Cell Carcinoma Growth.	CHD7 RCOR1 ZNF608 SMARCA4 KDM2B	7.17e-05	83	179	5	28794006
Pubmed	Positive correlations of liver enzymes with metabolic syndrome including insulin resistance in newly diagnosed type 2 diabetes mellitus.	GPT GOT1	7.88e-05	3	179	2	20972737
Pubmed	Elevated serum transaminase activities were associated with increased serum levels of iron regulatory hormone hepcidin and hyperferritinemia risk.	GPT GOT1	7.88e-05	3	179	2	26290281
Pubmed	Exosomes derived from GDNF-modified human adipose mesenchymal stem cells ameliorate peritubular capillary loss in tubulointerstitial fibrosis by activating the SIRT1/eNOS signaling pathway.	SIRT1 NOS3	7.88e-05	3	179	2	32802201
Pubmed	The human RAD18 gene product interacts with HHR6A and HHR6B.	UBE2A UBE2B	7.88e-05	3	179	2	10908344
Pubmed	CD28 inhibits T cell adhesion by recruiting CAPRI to the plasma membrane.	RASA4 RASA4B	7.88e-05	3	179	2	25637021
Interaction	H2BC8 interactions	HIRIP3 DIDO1 CHD7 MORC2 TERF2 TRRAP TGM2 RCOR1 FAM50A MDC1 SMARCA4 KDM2B USP39 SPRTN TRMT5 MGA CDCA5 TOP2B	1.91e-06	576	170	18	int:H2BC8
Cytoband	Ensembl 112 genes in cytogenetic band chr19p13	TSSK6 TGFBR3L APC2 TRMT1 GDF1 FARSA SAFB EFNA2 PTPRS SAFB2 SMARCA4 HOMER3	7.65e-05	797	179	12	chr19p13
GeneFamily	T cell receptor beta locus at 7q34	TRBV12-5 TRBV7-8 TRBV7-7 TRBV7-6 TRBV7-3	1.97e-04	87	111	5	372
GeneFamily	Pleckstrin homology domain containing\|Rho guanine nucleotide exchange factors\|C2 domain containing	SH3BP2 SPTB PLEKHG2 FGD1 PHLPP1 RASA4B PLEKHA7	2.81e-04	206	111	7	682
GeneFamily	GATA zinc finger domain containing\|Myb/SANT domain containing	CHD7 TERF2 DNAJC2 RCOR1	3.13e-04	53	111	4	532
GeneFamily	WASH complex	WASHC2C WASHC2A	5.51e-04	6	111	2	1331
GeneFamily	Pleckstrin homology domain containing\|SH2 domain containing\|C2 and RasGAP domain containing	RASA4 RASA4B	1.63e-03	10	111	2	830
Coexpression	THAKAR_PBMC_INACTIVATED_INFLUENZA_AGE_21_30YO_RESPONDERS_28DY_DN	CERK BICRA KATNB1 TRMT1 RAPGEF1 DIDO1 HIC2 TRRAP EPM2AIP1 PITPNM1 MAP7D1 EHBP1L1 NISCH MDC1 HELZ2 SAFB2 SMARCA4 CDK5RAP1 ALAD SRRM2 FUBP3	8.21e-07	905	176	21	M40865
ToppCell	saliva-Severe-critical_progression_d12-22_no-steroids-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c06-NR4A2\|Severe-critical_progression_d12-22_no-steroids / Compartment, severity and other cell annotations on 10x 3' data (130k)	SEC16B BNIP5 CARMIL2 ITGA2B PTPRS CCDC106 TRMT5 MGAT5B TBCD	1.66e-08	159	178	9	b1d5ebd0c186b6d0279dab20d8f3b4a915acdc1f
ToppCell	COVID-19-Heart-EC_2\|COVID-19 / Disease (COVID-19 only), tissue and cell type	ACACB APBB2 RAPGEF1 NALF1 MAST4 SYNJ2 NOS3 SMAD6	6.43e-07	179	178	8	2a53d94f6c30bf887dfe88f1693ea057218c852d
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPE ARHGEF15 SHROOM4 TGM2 RASA4 PCDH19 RASA4B NOS3	7.60e-07	183	178	8	a644258ba90acc62d571623e429d72ffc4b69203
ToppCell	RA-09._Endothelium_I\|World / Chamber and Cluster_Paper	APBB2 RAPGEF1 ARHGEF15 SHROOM4 NALF1 CRACDL NOS3 SMAD6	1.05e-06	191	178	8	c8a0c2af119bc34a8f694a7d30642f28002c84b9
ToppCell	RA-09._Endothelium_I\|RA / Chamber and Cluster_Paper	APBB2 RAPGEF1 ARHGEF15 SHROOM4 NALF1 CRACDL NOS3 SMAD6	1.09e-06	192	178	8	8a1b1c3e83a68ad74f8f4eb00455c9e41aa57cfc
ToppCell	LA-09._Endothelium_I\|World / Chamber and Cluster_Paper	RAPGEF1 ARHGEF15 SHROOM4 NALF1 CRACDL NOS3 TBCD SMAD6	1.23e-06	195	178	8	fc95457a298b5d0dab687d9ee7e225a7f7b9a0d4
ToppCell	LA-09._Endothelium_I\|LA / Chamber and Cluster_Paper	RAPGEF1 ARHGEF15 SHROOM4 NALF1 CRACDL NOS3 TBCD SMAD6	1.32e-06	197	178	8	ab6d1ab586a188597a39854ef980b8955ebcc645
ToppCell	5'-Adult-SmallIntestine-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPE SHROOM4 TGM2 NALF1 MAST4 RASA4 NOS3 SMAD6	1.48e-06	200	178	8	cd3c638961144a2fc91c437a173cc37c7452fa74
ToppCell	Control_saline-Endothelial-Endothelial-Vein\|Control_saline / Treatment groups by lineage, cell group, cell type	CPE LFNG TGM2 EHBP1L1 RASA4 NOS3 HOMER3 DCLK1	1.48e-06	200	178	8	e5f876910bc8cb390d9b46a48d9b6d4d57235551
ToppCell	BAL-Severe-cDC_4\|Severe / Compartment, Disease Groups and Clusters	CARMIL2 ACACB GPT VCAN NHS CCDC106 TRMT5	3.48e-06	158	178	7	73f66689ef59f71b14cb7141ca5951cc47fe57c1
ToppCell	368C-Myeloid-Dendritic-pDC\|368C / Donor, Lineage, Cell class and subclass (all cells)	CLIC3 PPM1J MDP1 PTPRS RASA4B ALPK2 LILRA4	5.01e-06	167	178	7	1e2fc1637769405a61f4c7e44945712a1888a299
ToppCell	Tracheal-10x5prime-Immune_Myeloid-Dendritic_cell-DC_plasmacytoid\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	BNIP5 CAMKK1 HLA-DQB2 INSM1 CLIC3 ALPK2 LILRA4	5.21e-06	168	178	7	c34dd4a9c54d8e9c8f118e6a3816548890cb0746
ToppCell	facs-Lung-EPCAM-18m-Endothelial-Vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 HIC2 CPE PPM1J CCDC57 TFB2M NOS3	5.63e-06	170	178	7	12203d4410f38cc933d9f160b5fb76828df94119
ToppCell	facs-Large_Intestine-Proximal-3m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACB SPTB MAST4 SLC18A3 ANO6 PIK3R5 DCLK1	5.63e-06	170	178	7	17bd7fd25a2657cb536ad47e294332920f759e95
ToppCell	facs-Lung-EPCAM-18m-Endothelial-vein_endothelial_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 HIC2 CPE PPM1J CCDC57 TFB2M NOS3	5.63e-06	170	178	7	f9decb3bf3bf6d4996b0ac27af768236e116aac5
ToppCell	368C-Myeloid-Dendritic-pDC\|Myeloid / Donor, Lineage, Cell class and subclass (all cells)	CLIC3 PPM1J MDP1 PTPRS RASA4B ALPK2 LILRA4	5.85e-06	171	178	7	714a0b0d0c9886fef64170cf53eb64f0d8a47280
ToppCell	droplet-Thymus-nan-21m-Lymphocytic-B_cell\|Thymus / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	PDCD1 TGFBR3L LARP1B GPR179 GGT7 LIPC CRYBG3	6.32e-06	173	178	7	0a0cd40bb5f61431fe34758626c8a63ec610a8a5
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_D_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	BNIP5 ANKRD6 GPR179 VCAN CACNA1G PLEKHA7 DCLK1	8.18e-06	180	178	7	8bf6e8b6b45ce42f8c5f23e7cd1752ec8b3fa2d2
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EXPH5 TMPRSS4 CPE MAST4 PALS2 PRKX	1.16e-05	190	178	7	1cf023e3c6924d6a06f353d4b62444b6f2fee8a7
ToppCell	COVID-19-Heart-EC_3\|Heart / Disease (COVID-19 only), tissue and cell type	APBB2 ARHGEF15 SHROOM4 TGM2 NALF1 NOS3 TBCD	1.16e-05	190	178	7	78e7c502b0450c0b37652b1896a2a752fd8a2111
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	USP9Y SSTR5 SLC18A3 SCN5A ZAR1	1.18e-05	74	178	5	0d705c42e7741b861ba5a9f1af83b2c5c6f23fb6
ToppCell	Posterior_cortex-Neuronal-Inhibitory-iN2(Gad1Gad2)-Synpr-Inhibitory_Neuron.Gad1Gad2-Chat.Synpr-Slc5a7_(Neuron.Gad1Gad2-Chat.Synpr-Slc5a7)-\|Posterior_cortex / BrainAtlas - Mouse McCarroll V32	USP9Y SSTR5 SLC18A3 SCN5A ZAR1	1.18e-05	74	178	5	c49bda52aa4ead9483c2f27d63458034e75699bd
ToppCell	5'-Adult-Appendix-Endothelial-blood_vessel_EC-Mature_venous_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	CPE ARHGEF15 SHROOM4 TGM2 NALF1 RASA4 NOS3	1.29e-05	193	178	7	c0973a2c97deb7176c2f617c8760a55f7edc9839
ToppCell	Endothelial-endothelial_cell_of_vein\|World / Lineage, Cell type, age group and donor	CPE ARHGEF15 SHROOM4 TGM2 NALF1 NOS3 SMAD6	1.33e-05	194	178	7	3cbd9622a68e89add90e589867d88c83c5a33476
ToppCell	LPS_only-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 ARHGEF15 SHROOM4 MAST4 ZNF608 CTNND1 DISP1	1.33e-05	194	178	7	58f069efdefa0366033764446b9d6ffd4a17807e
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 ARHGEF15 SHROOM4 MAST4 ZNF608 CTNND1 DISP1	1.33e-05	194	178	7	bfd92ec75facb0ba55c31e5f2e089d983b3d0169
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE TRIP11 SLC38A10 NISCH SRRM2 MGA	1.38e-05	195	178	7	7796ea9247f4c63762f0de8490fed08b9717fa23
ToppCell	LV-09._Endothelium_I\|LV / Chamber and Cluster_Paper	APBB2 RAPGEF1 ARHGEF15 SHROOM4 NALF1 TBCD SMAD6	1.47e-05	197	178	7	f9731d4d636e51b94a96805eee6afe9aedc175e3
ToppCell	Bronchial-NucSeq-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CPE ARHGEF15 SHROOM4 TGM2 NALF1 MGAT5B NOS3	1.57e-05	199	178	7	3a4deea6e11a0555d27497b7c9983350797aac69
ToppCell	Control_saline\|World / Treatment groups by lineage, cell group, cell type	FOXN2 ZBTB38 CLIC3 APBB2 ARHGEF15 CTNND1 MAP4K2	1.57e-05	199	178	7	11c9c1779caceb725ecccf3f23b7d4e6dbd1af64
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_systemic_arterial\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	ARHGEF15 SHROOM4 TGM2 MAST4 SYNJ2 NOS3 SMAD6	1.62e-05	200	178	7	5ec31c1be6bcc4124e1489d136570f3de33cc2e9
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / Treatment groups by lineage, cell group, cell type	ARHGEF15 TGM2 MAST4 ZNF608 HELZ2 CTNND1 DISP1	1.62e-05	200	178	7	edb64556b3fefe3144f73b6efe23b9ffd34091d2
ToppCell	LPS_only-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ARHGEF15 TGM2 MAST4 ZNF608 CTNND1 HOMER3 DISP1	1.62e-05	200	178	7	81e76508c9050d533853d5fd2f3097b27613d836
ToppCell	LPS_only-Endothelial-Endothelial\|LPS_only / Treatment groups by lineage, cell group, cell type	ARHGEF15 TGM2 MAST4 ZNF608 CTNND1 HOMER3 DISP1	1.62e-05	200	178	7	4bb609a284d4e6066f17470a1736076aa4a1f84c
ToppCell	Control-B_intermediate-1\|World / disease group and sub_cluster of B and Plasma cells(res = 0.5)	WASHC2C HLA-DQB2 WASHC2A EFNA2 CPLANE1 LILRA4	2.50e-05	144	178	6	984470ff6ddce4c743e2db78fa98dae055aaa273
ToppCell	droplet-Lung-21m-Hematologic-myeloid-classical_monocyte-classical_monocyte_l15\|21m / method, tissue, age, lineage, sublineage, cell ontologies, cell type and subtype	FOXN2 SPTB PITPNM1 FGD1 PALS2 CDCA5	5.36e-05	165	178	6	94a5211072464fc24592bb107a853ce832e816fe
ToppCell	COVID-CD8-exh_CD4\|COVID / Condition, Cell_class and T cell subcluster	LPCAT1 PLEKHG2 LIPC SYNJ2 NHS SPRTN	5.54e-05	166	178	6	4ca8c91b03d08489f244898cf9423b9d10348bc8
ToppCell	Ionocyte-iono-3\|World / Class top	RTN4R SKIDA1 LARP1B ANKRD6 RCOR1 FGD1	5.54e-05	166	178	6	9c4a780f8af46d7552077c7a0ae0ab1b2413e5d4
ToppCell	droplet-Marrow-nan-3m-Myeloid-basophil\|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ZBTB38 RAPGEF1 TRIP11 KANSL3 CACNA1G PRKX	6.12e-05	169	178	6	5f5bec13208f4c3b6eacbba180c8a6402743b76e
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Fezf2-Efna5_(Subiculum)\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CYP21A2 TGFBR3L SSTR5 LIPC	6.90e-05	55	178	4	358f064742bfa96d4809c64d69929d08c6003857
ToppCell	Hippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Excitatory_Neuron.Slc17a7.Fezf2-Efna5_(Subiculum)-\|Hippocampus / BrainAtlas - Mouse McCarroll V32	CYP21A2 TGFBR3L SSTR5 LIPC	6.90e-05	55	178	4	3af3086910affe70f85734cf9099bd8d8b8eafe4
ToppCell	367C-Myeloid-Dendritic-cDC_activated\|367C / Donor, Lineage, Cell class and subclass (all cells)	BNIP5 HLA-DQB2 INSM1 KDM2B ALPK2 FOXD4	6.96e-05	173	178	6	94f99f7e7813d6e53e0bedf97087400b1bf00129
ToppCell	facs-Large_Intestine-Distal-24m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CAMKK1 SPTB LIPC SCN5A PIK3R5 DCLK1	6.96e-05	173	178	6	f0eb48c1283bdde313bb75f6ffc0d2626922d24b
ToppCell	TCGA-Thryoid-Primary_Tumor-Thyroid_Papillary_Carcinoma-Tall_Cell\|TCGA-Thryoid / Sample_Type by Project: Shred V9	HLA-DQB2 TMPRSS4 CCN4 TGM2 SLC18A3 VCAN	6.96e-05	173	178	6	2e9dc137f3675eee07f941eb4cfcaf24a83ab0fb
ToppCell	facs-Large_Intestine-Distal-18m-Epithelial-Brush_cell_of_epithelium_proper_of_large_intestine\|Large_Intestine / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	ACACB SPTB MAST4 ANO6 PIK3R5 DCLK1	7.42e-05	175	178	6	f24b664b9056b5976bf2222e8013f15c09e049ad
ToppCell	renal_cortex_nuclei-Hypertensive_with+without-CKD-Immune-Myeloid-Macrophage_Dendritic-Plasmacytoid_Dendritic_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	CARMIL2 CLIC3 UBASH3A PTPRS PIK3R5 LILRA4	7.66e-05	176	178	6	8488997e0f02e874f53fae1690da63e0dd1d0780
ToppCell	Adult-Endothelial-endothelial_cell_of_vein\|Adult / Lineage, Cell type, age group and donor	CPE ARHGEF15 TGM2 NALF1 NOS3 SMAD6	7.66e-05	176	178	6	043683c61c5d1a7f8a4666a612310246bd3d83a2
ToppCell	Control\|World / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	ZBTB38 CLIC3 APBB2 USP9Y ARHGEF15 DISP1	7.90e-05	177	178	6	b8ff6940e31b749776e81ae4f5bbd577dba9749c
ToppCell	TCGA-Colorectal-Primary_Tumor-Colorectal_Adenocarcinoma-Rectal_Adenocarcinoma-7\|TCGA-Colorectal / Sample_Type by Project: Shred V9	ASXL1 DIDO1 DNAJC2 SHROOM4 VCAN FUBP3	8.15e-05	178	178	6	edc76b8f15056ec1c9a1c61a048b6331a92592d6
ToppCell	COVID-19-kidney-Epi_(Mes)\|COVID-19 / Disease (COVID-19 only), tissue and cell type	MYO9A HSPA12A LIPC NALF1 NHS ALPK2	8.15e-05	178	178	6	544379f5a6145429762258d426b876bb36c112f5
ToppCell	facs-Lung-Endomucin-24m-Myeloid-myeloid_dendritic_cell\|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation	HIRIP3 CAMKK1 LARP1B UMPS PALS2 CDCA5	8.40e-05	179	178	6	e520eadde4f1b7fb868dbbe94c4d62b3776c55eb
ToppCell	facs-Brain_Non-Myeloid-Cerebellum_-18m-Neuronal-Granular_Neuron_CB_Gabra6\|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CARMIL2 EXPH5 PNMA8B NALF1 RASA4 CACNA1G	8.66e-05	180	178	6	d76349ecef7c5878bf215e946f032264161eb61b
ToppCell	COVID-19-Heart-EC_3\|COVID-19 / Disease (COVID-19 only), tissue and cell type	APBB2 ARHGEF15 TGM2 NALF1 NOS3 TBCD	9.49e-05	183	178	6	ff95382cfed592190d0636d2b750328471f82e0d
ToppCell	COVID-19-kidney-PCT-S1\|kidney / Disease (COVID-19 only), tissue and cell type	SEC16B CPE MAST4 NHS PALS2 ALPK2	9.78e-05	184	178	6	51ed1ebfdef45149541917c66cbacad87072e51f
ToppCell	368C-Lymphocytic-CD8+_Cytotoxic_T-cell-CD8+_Cytotoxic_T_cell_0\|368C / Donor, Lineage, Cell class and subclass (all cells)	PDCD1 MORC2 FANCF TACC3 CPLANE1 MGA	9.78e-05	184	178	6	d48807f9da48bdd015a54c606d2e2a311f181396
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-Epcam____podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	CLIC3 CPE PNMA8B HSPA12A SCN5A MGAT5B	1.01e-04	185	178	6	872720275789d249c9859de825a923803d458875
ToppCell	5'-Parenchyma_lung-Mesenchymal-Fibroblastic-fibroblastic_type_1-Adventitial_fibroblasts-Adventitial_fibroblasts_L.2.1.0.2\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	SHQ1 CCN4 FANCF FARSA MDP1 TESK2	1.01e-04	185	178	6	9878392d79734ab5bb977d7f4f5e2e079b9a5353
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	SEMA4D MYO9A CPE NHS PALS2 PRKX	1.04e-04	186	178	6	f0c8de4f6ae9047b9108a47a2af8c5f42bc103b0
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Proximal_Tubule_Epithelial_Cell\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	MAST4 ZNF608 NHS PALS2 DCLK1 ALPK2	1.04e-04	186	178	6	b87acc80b7baa41681e4ed11d5537b9fbf5832f5
ToppCell	renal_cortex_nuclei-CKD+DKD_normotensive-Epithelial-Proximal_tubule_epithelial_cell-kidney_proximal_tubule_epithelial_cell-Proximal_Tubule_Epithelial_Cell_Segment_3\|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group	ZBTB38 SH3BP2 GPT MAST4 PLEKHA7 ALPK2	1.04e-04	186	178	6	b1edc341d6684b347dc9e21b34f62f51d095d735
ToppCell	metastatic_Lymph_Node-Endothelial_cells-Tumor_ECs\|metastatic_Lymph_Node / Location, Cell class and cell subclass	SEC16B ARHGEF15 SHROOM4 RASA4 MDC1 NOS3	1.07e-04	187	178	6	2713f526f86911fbbf6c7a3e69230f2e6bde31c3
ToppCell	COVID-19-Heart-EC_2\|Heart / Disease (COVID-19 only), tissue and cell type	APBB2 RAPGEF1 NALF1 MAST4 SYNJ2 SMAD6	1.07e-04	187	178	6	40ffc06a3e3251d9b12da390210d3e045af7537a
ToppCell	droplet-Kidney-KIDNEY-1m-Epithelial-podocyte\|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB CPE PNMA8B HSPA12A SCN5A MGAT5B	1.07e-04	187	178	6	806075c2531a7f5c1da38b85ea494a3b4b5e92ec
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EXPH5 TMPRSS4 CPE PALS2 PRKX	1.07e-04	187	178	6	c41a2c81dd2ceef303f39f699032aa7d6ea67cf0
ToppCell	RA-10._Endothelium_II\|World / Chamber and Cluster_Paper	RAPGEF1 TGM2 NALF1 VCAN NOS3 SMAD6	1.13e-04	189	178	6	75c248b9de5e2fb7a0baa8cdbab516e575cc4394
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG2 ANKLE2 NALF1 NHS MGAT5B ALPK2	1.13e-04	189	178	6	8c8ca3b30d9be6c854615459a7bfba82b427c8bc
ToppCell	renal_papilla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell\|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group	PLEKHG2 ANKLE2 NALF1 NHS MGAT5B ALPK2	1.13e-04	189	178	6	5d902a4660a27548764bf04c6de152b565da835c
ToppCell	renal_papilla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_ascending_limb_epithelial_cell-Ascending_Thin_Limb_Cell\|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group	MYO9A EXPH5 TMPRSS4 MAST4 PALS2 PRKX	1.17e-04	190	178	6	59bbbd2c8d4b7ce46c54ca8022b1557e7e5eee2a
ToppCell	PCW_13-14\|World / Celltypes from embryonic and fetal-stage human lung	ZBTB38 USP9Y FRMD1 NALF1 MAST4 CRYBG3	1.17e-04	190	178	6	62a3ec1ae0829602b0569cc051210551644f1d46
ToppCell	5'-Adult-LymphNode-Endothelial-blood_vessel_EC\|Adult / Celltypes from developing, pediatric, Crohn's, & adult GI tract	ARHGEF15 SHROOM4 TGM2 RASA4 RASA4B NOS3	1.17e-04	190	178	6	141266bf411ea675fbf889b20c1b08673c45ff95
ToppCell	RV-06._Ventricular_Cardiomyocyte_II\|RV / Chamber and Cluster_Paper	ACACB PPP1R12B MAST4 SCN5A ALPK2 GOT1	1.17e-04	190	178	6	fe8e78922c8ae928ef9a80bffd67868d5a87a091
ToppCell	LPS_only-Endothelial-Endothelial-Activated_Alv_Cap\|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 TGM2 MAST4 ZNF608 CTNND1 DISP1	1.20e-04	191	178	6	a7b18bcf27c38ad2353c239ecb309c80f3ef3359
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE PNMA8B SLC38A10 NISCH SRRM2	1.23e-04	192	178	6	1304e69c92cef3bd8c82e3c035a7562f5440139a
ToppCell	droplet-Pancreas-Endocrine\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE PNMA8B SLC38A10 NISCH SRRM2	1.23e-04	192	178	6	0dfd1e9896c34aee0f842f8de5d0e3af62a15f68
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.1.0\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPE ARHGEF15 SHROOM4 TGM2 NALF1 NOS3	1.27e-04	193	178	6	c0f0052c24b7fe9e21d2bc6c38047a8e755f87b6
ToppCell	LPS-antiTNF-Endothelial-Endothelial-Gen_Cap\|LPS-antiTNF / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 ARHGEF15 SHROOM4 MAST4 ZNF608 CTNND1	1.27e-04	193	178	6	6e1982d089a9de628e6006d23ff78a223fbd9f47
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE SLC38A10 MROH1 NISCH SMARCA4	1.27e-04	193	178	6	471e65f02937bc18d7c5facdacdf1df58cf0f839
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE SLC38A10 MROH1 NISCH SMARCA4	1.27e-04	193	178	6	fe451b3295d77b2bd1ac25cf29310c85835a45fe
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPE ARHGEF15 SHROOM4 TGM2 NALF1 NOS3	1.27e-04	193	178	6	682ce63b73a7d02eef240673db67058d7507f744
ToppCell	droplet-Pancreas-Endocrine-21m\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE SLC38A10 NISCH SMARCA4 SRRM2	1.31e-04	194	178	6	3a3ecedcdc7691cf21775818b598208fcb980c29
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CARMIL2 INSM1 CLIC3 PPM1J PTPRS LILRA4	1.31e-04	194	178	6	bb36274d6fe2d18c545a17d3809f331586502d01
ToppCell	3'-GW_trimst-1.5-SmallIntestine-Neuronal-neurons_B\|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract	TCEAL2 APC2 PTPRS SLC18A3 SCN5A DCLK1	1.31e-04	194	178	6	15224fb3e7ca5bd1fb8c41f8275842f737014095
ToppCell	droplet-Pancreas-Endocrine-18m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE PNMA8B SLC38A10 NISCH SRRM2	1.31e-04	194	178	6	92b39a935e8c577eb1123d706d168fa13cf3344c
ToppCell	LPS-IL1RA-Endothelial-Endothelial-Gen_Cap\|LPS-IL1RA / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2	APBB2 ARHGEF15 SHROOM4 MAST4 ZNF608 CTNND1	1.31e-04	194	178	6	0b9cd96fa0b616da7cc90e92ff71157e9bba518f
ToppCell	Fetal_29-31_weeks-Endothelial-endothelial_cell_of_vein\|Fetal_29-31_weeks / Lineage, Cell type, age group and donor	ARHGEF15 SHROOM4 TGM2 MRAP2 NOS3 SMAD6	1.31e-04	194	178	6	fc2e0081005c0c496e41197a2d06e4a37708221f
ToppCell	medial-2-Hematologic-Plasmacytoid_Dendritic\|2 / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CARMIL2 INSM1 CLIC3 PPM1J PTPRS LILRA4	1.31e-04	194	178	6	d58be6454a0795d6771036a1620553a153861615
ToppCell	RA-03._Atrial_Cardiomyocyte\|RA / Chamber and Cluster_Paper	ACACB PPP1R12B MAST4 ZNF608 SCN5A ALPK2	1.31e-04	194	178	6	c3535f7cc0076653c72db582047cff053c322397
ToppCell	medial-Hematologic-Plasmacytoid_Dendritic-2\|medial / Location, Lineage, Cell class (ontology) and Donor from 10X sequencing (macrophage renamed)	CARMIL2 INSM1 CLIC3 PPM1J PTPRS LILRA4	1.31e-04	194	178	6	0117cd68750153fd6b8978c8b4ce3589486d2b5f
ToppCell	droplet-Pancreas-Endocrine-21m-Epithelial\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE SLC38A10 NISCH SMARCA4 SRRM2	1.31e-04	194	178	6	0b023de48ed8a550d169bbe954881eb04bf4f981
ToppCell	Tracheal-NucSeq-Endothelial-Endothelia_vascular-VE_systemic_arterial\|NucSeq / Cell types per location group and 10X technology with lineage, and cell group designations	CLIC3 CMPK2 ARHGEF15 NALF1 NOS3 SMAD6	1.34e-04	195	178	6	517af3e6784f02c382df6f5691945eefaa9ec4ae
ToppCell	3'-Distal_airway-Endothelial-Blood_vessel_EC-vein_endothelial_cell\|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPE ARHGEF15 SHROOM4 TGM2 NALF1 NOS3	1.34e-04	195	178	6	53b83e16b350100b1d5791a9c42bd98e37cbc0af
ToppCell	LV-09._Endothelium_I\|World / Chamber and Cluster_Paper	CLIC3 RAPGEF1 ARHGEF15 SHROOM4 CRACDL TBCD	1.34e-04	195	178	6	19e0a6c3eae1615aaa39767300acd937dfcb2a7f
ToppCell	5'-Parenchyma_lung-Endothelial-Blood_vessel_EC-vein_endothelial_cell-EC_venous_pulmonary-EC_venous_pulmonary_L.2.2.2.0\|5' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5	CPE ARHGEF15 TGM2 RASA4 RASA4B NOS3	1.34e-04	195	178	6	81a98ebb0d43f416f9a8bba580531dc0cfea8f74
ToppCell	droplet-Pancreas-PANCREAS-30m-Epithelial-pancreatic_B_cell\|Pancreas / Large_Intestine_Pancreas_Liver - method, tissue, subtissue, age, lineage, cell ontology and free annotation	INSM1 CPE SLC38A10 NISCH SRRM2 MGA	1.34e-04	195	178	6	3e519cffa6144a62b06124642a14c9ff39b76554
ToppCell	facs-Bladder-nan-3m\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 SLC38A10 SND1 PTPRS NISCH TOP2B	1.38e-04	196	178	6	44f5b1b474399c9316729155f2ea95a82ca66e30
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB CCN4 SCN5A PYGM ALPK2 GOT1	1.38e-04	196	178	6	a582130862bee76c0385156a333bfdfc75cf218b
ToppCell	droplet-Heart-HEART-1m-Mesenchymal-atrial_cardiomyocyte\|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation	SPTB CCN4 SCN5A PYGM ALPK2 GOT1	1.38e-04	196	178	6	fba52a4b82086dbae9a55038bf44c4539be926f5
ToppCell	facs-Bladder-nan-3m-Epithelial\|Bladder / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation	TGM2 SLC38A10 SND1 PTPRS NISCH TOP2B	1.38e-04	196	178	6	c0e90d964baa2eb4fbd18a52379ccec5d3bf59a8
ToppCell	ILEUM-non-inflamed-(7)_Endothelial_cell-(7)_ACKR1+_endothelial_cells\|(7)_Endothelial_cell / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)	CPE ITGAE TGM2 NALF1 RASA4 PCDH19	1.42e-04	197	178	6	143607d195c8aa2b94d995af0b2ef38582565611
ToppCell	Tracheal-10x5prime-Endothelial-Endothelia_vascular-VE_pulmonary_venous\|10x5prime / Cell types per location group and 10X technology with lineage, and cell group designations	CPE TGM2 NALF1 MGAT5B NOS3 SMAD6	1.42e-04	197	178	6	a78111171819db746af7b162c77f9a324453f3ce
Drug	Flucloxacillin sodium [1847-24-1]; Up 200; 8.4uM; PC3; HT_HG-U133A	ELOA2 SPTB CLIC3 KANSL3 UBE2B VCAN RAB3GAP2 CPLANE1 PIK3R5 HOMER3	2.93e-06	198	173	10	5102_UP
Drug	RU 58668	ETV4 SAFB EFNA2 SAFB2 NOS3	4.77e-06	33	173	5	CID000119604
Drug	formononetin	SIRT1 SAFB NISCH SAFB2 TACC3	5.56e-06	34	173	5	CID005280378
Drug	Iproniazide phosphate [305-33-9]; Down 200; 14.4uM; PC3; HT_HG-U133A	SH3BP2 TRIP11 PITPNM1 EHBP1L1 MAST4 SMARCA4 PRKX MAP4K2 SMAD6	1.91e-05	195	173	9	2125_DN
Drug	Chlorpromazine hydrochloride [69-09-0]; Down 200; 11.2uM; HL60; HT_HG-U133A	ACACB SH3BP2 HIC2 CCNT1 SYNJ2 VCAN PALS2 SRRM2 SMAD6	1.99e-05	196	173	9	1864_DN
Drug	Naftifine hydrochloride [65473-14-5]; Down 200; 12.4uM; HL60; HT_HG-U133A	EXPH5 BICRA SH3BP2 KATNB1 DIDO1 CHD7 EHBP1L1 SYNJ2 SAFB2	1.99e-05	196	173	9	2974_DN
Drug	Perphenazine [58-39-9]; Down 200; 10uM; HL60; HG-U133A	SH3BP2 ARHGEF15 SYNJ2 NISCH SMARCA4 ALAD TACC3 PALS2 TBCD	2.07e-05	197	173	9	2040_DN
Drug	Picotamide monohydrate [80530-63-8]; Down 200; 10.2uM; PC3; HT_HG-U133A	DIDO1 NALF1 MAST4 VCAN SAFB2 FGD1 SRRM2 MAP4K2 SMAD6	2.07e-05	197	173	9	2070_DN
Drug	Azacyclonol [115-46-8]; Down 200; 15uM; HL60; HG-U133A	ASXL1 IRF2BP1 TRMT1 PITPNM1 CCNT1 FANCF SMARCA4 SAC3D1 PALS2	2.15e-05	198	173	9	2020_DN
Drug	Benzydamine hydrochloride [132-69-4]; Up 200; 11.6uM; HL60; HG-U133A	MYO9A BICRA SH3BP2 SPTB TERF2 CCNT1 FANCF SYNJ2 SMAD6	2.24e-05	199	173	9	1552_UP
Drug	(cis-) Nanophine [5072-45-7]; Down 200; 26.8uM; PC3; HT_HG-U133A	SEMA4D HIRIP3 CHD7 NALF1 FGD1 CPLANE1 SRRM2 PRKX MAP4K2	2.24e-05	199	173	9	4543_DN
Disease	Insulin Resistance	ACACB CPE SIRT1 LIPC NOS3	2.19e-05	60	165	5	C0021655
Disease	Insulin Sensitivity	ACACB CPE SIRT1 LIPC NOS3	2.19e-05	60	165	5	C0920563
Disease	Hypertension, Goldblatt	TRIP11 NOS3	3.11e-05	2	165	2	C0018036
Disease	lean body mass	SEC16B ZBTB38 CYP21A2 APC2 DIDO1 ANKRD6 VCAN TACC3 NOS3 SMAD6	5.82e-05	379	165	10	EFO_0004995
Disease	metabolic syndrome	SEC16B SEMA4D HLA-DQB2 LIPC SMARCA4 CDCA5 MAP4K2	1.39e-04	200	165	7	EFO_0000195
Disease	carpal tunnel syndrome	ZBTB38 HLA-DQB2 VCAN UMPS SMAD6	1.46e-04	89	165	5	EFO_0004143
Disease	Genomic Instability	SIRT1 SPRTN	3.07e-04	5	165	2	C0919532
Disease	acute kidney failure (biomarker_via_orthology)	GPT SIRT1 ALAD NOS3	3.84e-04	61	165	4	DOID:3021 (biomarker_via_orthology)
Disease	Urogenital Abnormalities	APC2 FGD1	6.41e-04	7	165	2	C0042063
Disease	focal segmental glomerulosclerosis (implicated_via_orthology)	MYO9A LIPC	6.41e-04	7	165	2	DOID:1312 (implicated_via_orthology)
Disease	metabolite measurement, diet measurement	HLA-DQB2 CYP21A2 LIPC SMARCA4	6.84e-04	71	165	4	EFO_0004725, EFO_0008111
Disease	Mammary Carcinoma, Human	RIBC2 PPP1R12B APC2 ETV4 SIRT1 TGM2 SYNJ2 NISCH UMPS NOS3	7.82e-04	525	165	10	C4704874
Disease	Mammary Neoplasms, Human	RIBC2 PPP1R12B APC2 ETV4 SIRT1 TGM2 SYNJ2 NISCH UMPS NOS3	7.82e-04	525	165	10	C1257931
Disease	Mammary Neoplasms	RIBC2 PPP1R12B APC2 ETV4 SIRT1 TGM2 SYNJ2 NISCH UMPS NOS3	8.05e-04	527	165	10	C1458155
Disease	alcohol use disorder (implicated_via_orthology)	CLIC3 SIRT1 SMARCA4 SRRM2 HOMER3 MAP4K2	8.27e-04	195	165	6	DOID:1574 (implicated_via_orthology)
Disease	Hereditary spherocytosis	SPTB UMPS	8.51e-04	8	165	2	C0037889
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	HLA-DQB2 LIPC SMARCA4	9.05e-04	34	165	3	EFO_0008317, EFO_0008596, EFO_0020944
Disease	Breast Carcinoma	RIBC2 PPP1R12B APC2 ETV4 SIRT1 TGM2 SYNJ2 NISCH UMPS NOS3	9.41e-04	538	165	10	C0678222
Disease	neuroimaging measurement	SEMA4D HLA-DQB2 CYP21A2 SKIDA1 CHD7 CCN4 NALF1 MAST4 SND1 VCAN RAB3GAP2 UMPS TACC3 PLEKHA7 DCLK1	1.02e-03	1069	165	15	EFO_0004346
Disease	zinc fingers and homeoboxes protein 3 measurement	HLA-DQB2 CYP21A2	1.09e-03	9	165	2	EFO_0803299
Disease	vitamin D deficiency	LIPC SMARCA4 PADI1	1.16e-03	37	165	3	EFO_0003762
Disease	very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	ACACB IRF2BP1 HLA-DQB2 CYP21A2 LIPC HELZ2 SMARCA4	1.30e-03	291	165	7	EFO_0008317, EFO_0020946
Disease	cholesterol:total lipids ratio, low density lipoprotein cholesterol measurement	HLA-DQB2 CYP21A2 EHBP1L1 LIPC SMARCA4	1.32e-03	144	165	5	EFO_0004611, EFO_0020943
Disease	Tachycardia, Ventricular	SCN5A NOS3	1.65e-03	11	165	2	C0042514
Disease	fibrinogen measurement, coronary artery disease	HLA-DQB2 CYP21A2 SMARCA4 UMPS NOS3	1.78e-03	154	165	5	EFO_0001645, EFO_0004623
Disease	mean platelet volume	ZBTB38 PCDHGB2 CYP21A2 TRMT1 CHD7 ITGA2B LFNG RCOR1 NALF1 MAST4 TESK2 UMPS NOS3 TBCD	1.84e-03	1020	165	14	EFO_0004584
Disease	von Willebrand factor measurement, coagulation factor measurement	ANKRD6 SAFB2	1.98e-03	12	165	2	EFO_0004629, EFO_0004634
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, cholesterol:total lipids ratio	HLA-DQB2 LIPC SMARCA4	2.18e-03	46	165	3	EFO_0008317, EFO_0008596, EFO_0020943
Disease	cardiomyopathy (biomarker_via_orthology)	NOS3 GOT1	2.33e-03	13	165	2	DOID:0050700 (biomarker_via_orthology)
Disease	Genetic chronic primary adrenal insufficiency	HLA-DQB2 UBASH3A	2.33e-03	13	165	2	Orphanet_101960
Disease	reticulocyte measurement	SEMA4D FOXN2 HLA-DQB2 SPTB TRMT1 LFNG ARHGEF15 GGT7 RCOR1 NISCH TESK2 ALAD CTNND1 PLEKHA7	2.46e-03	1053	165	14	EFO_0010700
Disease	vitamin D measurement	CYP21A2 SLC38A10 LIPC NALF1 SMARCA4 PLEKHA7 PADI1	2.93e-03	336	165	7	EFO_0004631
Disease	cup-to-disc ratio measurement	HLA-DQB2 RAPGEF1 CCDC57 HSPA12A EHBP1L1 VCAN CTNND1 DCLK1	3.00e-03	430	165	8	EFO_0006939
Disease	level of Phosphatidylcholine (16:0_16:0) in blood serum	LIPC SMARCA4	3.11e-03	15	165	2	OBA_2045067
Disease	gallstones	IRF2BP1 CYP21A2 SKIDA1 SYNJ2	3.22e-03	108	165	4	EFO_0004210
Disease	syndromic intellectual disability (implicated_via_orthology)	UBE2A UBE2B	3.54e-03	16	165	2	DOID:0050888 (implicated_via_orthology)
Disease	sickle cell anemia (is_implicated_in)	ALAD NOS3	3.54e-03	16	165	2	DOID:10923 (is_implicated_in)
Disease	Intellectual Disability	APC2 TRMT1 TRRAP SHROOM4 UMPS CACNA1G TFB2M TBCD	3.79e-03	447	165	8	C3714756
Disease	very low density lipoprotein cholesterol measurement, cholesteryl esters:total lipids ratio	SEC16B SEMA4D IRF2BP1 LIPC HELZ2 SMARCA4	3.80e-03	264	165	6	EFO_0008317, EFO_0020944
Disease	cytochrome-c oxidase deficiency disease (implicated_via_orthology)	COA3 TRMT5	4.00e-03	17	165	2	DOID:3762 (implicated_via_orthology)
Disease	Lipidemias	LIPC NOS3	4.00e-03	17	165	2	C1706412
Disease	pre-eclampsia (biomarker_via_orthology)	PDCD1 NOS3	4.00e-03	17	165	2	DOID:10591 (biomarker_via_orthology)
Disease	level of Sphingomyelin (d32:1) in blood serum	LIPC SMARCA4	4.00e-03	17	165	2	OBA_2045173
Disease	Hyperlipidemia	LIPC NOS3	4.00e-03	17	165	2	C0020473
Disease	pyroglutamine measurement	CYP21A2 ANKRD6 NALF1	4.23e-03	58	165	3	EFO_0005408
Disease	level of Sphingomyelin (d34:1) in blood serum	LIPC SMARCA4	4.48e-03	18	165	2	OBA_2045175
Disease	chylomicron measurement, very low density lipoprotein cholesterol measurement, phospholipids:total lipids ratio	HLA-DQB2 LIPC SMARCA4	4.87e-03	61	165	3	EFO_0008317, EFO_0008596, EFO_0020946
Disease	Congenital Myasthenic Syndromes, Presynaptic	MYO9A SLC18A3	4.99e-03	19	165	2	C0751884
Disease	seborrheic dermatitis	TNRC18 MAST4	5.53e-03	20	165	2	EFO_1000764
Disease	neoplasm of mature B-cells	HLA-DQB2 PHLPP1	5.53e-03	20	165	2	EFO_0000096

Protein segments in the cluster

Peptide	Gene	Start	Entry
SSPNFPDDAKKRAER	GPT	96	P24298
RAFAGPLSPAKAEDF	ANKLE2	521	Q86XL3
RISFFLEKENEPPGR	CDCA5	81	Q96FF9
NPDPSLKEFEGATLR	APBB2	376	Q92870
PKDPEAAEARRGQFE	VCAN	1421	P13611
SRFFAPRSPSRDKEE	CRYBG3	16	Q68DQ2
DSPGRLSPFIENVDK	CRYBG3	2271	Q68DQ2
PKDARADFREPVAVS	ALPK2	761	Q86TB3
TRRSPDVLKDFAPGS	CLIC3	46	O95833
PAEEEATLGARPDKR	CARMIL2	1181	Q6F5E8
EVERLFKATSPRGEP	SH3BP2	466	P78314
AAIDAPDFFGDTPKR	ANKRD66	101	B4E2M5
AARELTPTPDDAVFR	CPXM1	516	Q96SM3
PKPTRVRQDATIFGD	ARHGEF15	281	O94989
RPRKTAPRDTGAFDA	CCN4	191	O95388
NSPSRRFGVDPDKEL	CCNT1	21	O60563
RTPFKDEIDEFANSP	CHD7	1861	Q9P2D1
PVKRRAFNSVDPTFD	DNAJC2	151	Q99543
RLAPDPDREGKVIFS	DISP1	1061	Q96F81
ASASFPEKKPRLEDR	ASXL1	531	Q8IXJ9
REEFLSASPEPRAKD	ANKRD6	321	Q9Y2G4
QRPALKAEFDRPVSE	ETV4	436	P43268
PDFDPAKLARRSQER	RCOR1	116	Q9UKL0
APKDRNGTSDPFVRV	RASA4	146	O43374
FPVVFDSPRNRGLKD	PADI1	366	Q9ULC6
APKDRNGTSDPFVRV	RASA4B	146	C9J798
KFGAPRRKETDPLNE	MAP4K2	336	Q12851
ARITSENPDEGFKPS	ACACB	651	O00763
RTPEFEEFNGKPDSL	ANO6	46	Q4KMQ2
TRPSEAEPRGADSEK	PCDH19	1106	Q8TAB3
ERVPEKADFSPFGNS	RAB3GAP2	441	Q9H2M9
ALSSPKFREEAAFPG	ELOA2	491	Q8IYF1
ARQKAPAPELDRFEE	C22orf23	146	Q9BZE7
DFSPENSDAGRKPVR	LPCAT1	516	Q8NF37
ANSRKDNAPFRVVEP	LILRA4	481	P59901
EVGKAEAERPARFLS	FANCF	176	Q9NPI8
AAEVSPAKEENPRRA	HIRIP3	121	Q9BW71
VKGPFSVEADPSRFR	LFNG	346	Q8NES3
PSKAFEREVERPVAN	MDC1	911	Q14676
SADEKAAERSRKAPP	MGA	2386	Q8IWI9
DPPFHKSSDGTVRDR	MDP1	26	Q86V88
ADLGPRERAVTAPEK	GPR179	1736	Q6PRD1
VPSRVPKDERGSAAD	ALAD	81	P13716
DRALPDFKGIQTSDP	HDHD2	96	Q9H0R4
KRSFGNPFEPQARRE	CAMKK1	456	Q8N5S9
VFPAFQSSGLEKPDR	KIAA2026	2086	Q5HYC2
FDLSAVEPAERPSRA	GDF1	131	P27539
PATRNEPIGLKASDF	KATNB1	456	Q9BVA0
GSPSEVRENKDFIRP	DCLK1	171	O15075
EEKLFRSQSADAPGP	HOMER3	151	Q9NSC5
PDRFLEPGKNSRALA	CYP21A2	406	P08686
STPVAEARDFPKDFL	HLA-DQB2	26	P05538
GSIDPPDFQRAKDFI	ITGAE	211	P38570
EGRRDQCEAPSDPKF	MGAT5B	151	Q3V5L5
TDKLAAFPEDRSQPG	PDCD1	76	Q15116
APAAPLRGRKDEDAF	GGT7	36	Q9UJ14
DGSPLRETRKDPFSA	GGT7	81	Q9UJ14
IAVKDPRSPDAAGAT	GGT7	646	Q9UJ14
SDRREPSDPQAKLQF	PCDHGB2	676	Q9Y5G2
RIQFKPDDGISPERA	FUBP3	286	Q96I24
GAPRASSPEKAEEDR	EHBP1L1	1011	Q8N3D4
SSPEKAEEDRRLPGS	EHBP1L1	1016	Q8N3D4
SLKPEPFGRRAQAVE	LIPC	26	P11150
FSRRSPSDKDPSLGE	EXPH5	906	Q8NEV8
FESRKRAAAPDRTNP	HSPA12A	386	O43301
ANLDRAPDPTVRKDA	MROH1	201	Q8NDA8
APDPTVRKDAFATDI	MROH1	206	Q8NDA8
FQKPETRREFDLSDP	RIBC2	106	Q9H4K1
RSAAASEDARQPAKP	FOXD4	91	Q12950
SARDGPERSVPKEAE	CRACDL	426	Q6NV74
DAEAAAPERPKAERA	CRACDL	531	Q6NV74
KAERAEAPPAGAERA	CRACDL	541	Q6NV74
AETSPEGTKPERRSF	MORC2	226	Q9Y6X9
GRVLTAFSREPDNPK	NOS3	1071	P29474
DFLPVDPSASNGRIK	PTPRS	171	Q13332
PFTSRKPREDEKDGQ	PALS2	371	Q9NZW5
RNEGNEKPRAPFVAF	FRMD1	126	Q8N878
AFTRERPQGRKEAPA	APC2	1536	O95996
DLPSSVVFPDREAAR	CMPK2	206	Q5EBM0
IDAPRKPSIDGFSSD	KDM2B	391	Q8NHM5
FFVRTGPEEPREKAS	BNIP5	106	P0C671
PFPRKGEERNEASFQ	CCDC125	61	Q86Z20
RRNFEEPPEAASSAL	CCDC106	41	Q9BWC9
FASERDGDTLPDRKN	CACNA1G	891	O43497
AEKRGQEHDPFCPRS	CPLANE1	2916	Q9H799
LPVASFTPEERAARA	EPM2AIP1	86	Q7L775
RLFARGIEENPKPDS	CERK	521	Q8TCT0
LGKNPDVDTSFLPDR	FAM50A	156	Q14320
NRPPCRKNDDDSSFV	CPE	296	P16870
ARDPKPEASRASDAG	DIDO1	2221	Q9BTC0
LTADFREDPDPRKVN	GOT1	21	P17174
PPASDAVALGREDAK	CCDC57	736	Q2TAC2
DSKRGEAPFAQRIDP	COA3	11	Q9Y2R0
RFFRNPAKPAEEDVA	DRC7	591	Q8IY82
RRASNEKESAAPASP	MAP7D1	531	Q3KQU3
SPAVSLPDPEFKRDR	MAST4	1886	O15021
RSPGKAEAESDALPD	DDX24	286	Q9GZR7
PPFARAEDAARANSD	EFNA2	21	O43921
GSLPEAVDAARPKAT	FOXN2	31	P32314
DLAFEVPERGSRPAS	KANSL3	501	Q9P2N6
AKREGPPFISEAAVR	EMC6	6	Q9BV81
KRESPFDKRPTAAEI	FAM186A	551	A6NE01
VKAEPGDEALSPASR	HELZ2	996	Q9BYK8
PAKRRKSESPDVDQA	BICRA	1471	Q9NZM4
ADPQRAVKEYSRPAA	SAC3D1	91	A6NKF1
GPDTEPRAAQAKLRD	SLC38A10	821	Q9HBR0
NDTVDFPKRTSPARG	CTNND1	641	O60716
DGVRSFREPAPAEAL	IRF2BP1	336	Q8IU81
FRVDPPISDEFGRKR	LARP1B	846	Q659C4
ARAPEPEAAARAEAR	INSM1	326	Q01101
KKEPVAGSPFERREA	HIC2	341	Q96JB3
ADKASVLEPGRPASA	RTN4R	341	Q9BZR6
PEDVAQRAARLKTFP	TRMT1	591	Q9NXH9
DPPLKRQRTAEAFSD	TRMT5	486	Q32P41
ADKYPEEPERSRALG	SLC18A3	201	Q16572
PSGRPREAKLVEFDF	TACC3	591	Q9Y6A5
DKPRAAPRAQSGSDS	SRRM2	1606	Q9UQ35
DNERSIPSLVDGFKP	TOP2B	731	Q02880
ERDAAGAPRDASDPL	SMAD6	131	O43541
KREFEPASAREAPAS	USP39	51	Q53GS9
DKSAADGPRVFRVVD	FARSA	116	Q9Y285
RDPIDPVSAGASAAK	SYNJ2	1446	O15056
KLSDTEDVFPRRAGP	TGFBR3L	66	H3BV60
DASCRQDFSPERPKA	NHS	731	Q6T4R5
EASEPEDRASRKPRA	PNMA8B	521	Q9ULN7
LADRGKKTEEPPRDF	PYURF	36	Q96I23
DPRVAKGLAPRAEAS	FGD1	191	P98174
PAAFEDAGRLPDLKS	SKIDA1	496	Q1XH10
RDRSKARSPYSPAEE	PLEKHA7	356	Q6IQ23
TPAKAVEARASFSRP	PPM1J	56	Q5JR12
EDRLPKSDSEDGPRA	SCN5A	491	Q14524
PSRGSRAKPVVSDDD	SMARCA4	1616	P51532
IKDPDFTPAAERRQK	SHQ1	171	Q6PI26
DREAASSPAGEPLRK	SIRT1	21	Q96EB6
EASAELAKASFGRPP	SHROOM4	386	Q9ULL8
RRAAATQPDAKDTPD	SND1	61	Q7KZF4
DFRNPPRKASKASLD	TFB2M	56	Q9H5Q4
FVFADVIRKSPDSPD	SEMA4D	211	Q92854
VGFFKRNRPPLEEDD	ITGA2B	1021	P08514
GAKDADATEPRPDRI	SSTR5	326	P35346
AEEKPARALPAQDDR	SOWAHB	221	A6NEL2
EAPSPEARDSKEDGR	SAFB	341	Q15424
ASRAAARPKPSASEV	C15orf61	21	A6NNL5
CPSPERQEDGARKDF	CDK5RAP1	41	Q96SZ6
AGTKARFPLRDAVEE	TGM2	71	P21980
APDGPSSTARLDFKV	PITPNM1	676	O00562
LKRDPERPESAKAFG	TNRC18	651	O15417
VSDFGRPLEPDKVFS	MRAP2	91	Q96G30
DPVRTNFDAFPDKVA	PYGM	321	P11217
RRRPFLSGDEDPKAS	PIK3R5	501	Q8WYR1
DSRDGSERAPKSPDA	RAPGEF1	641	Q13905
AFRTGDLDSKPDPSR	SOGA1	551	O94964
DSGLPKDRFFAVRPE	TRBV7-3	76	A0A075B6L6
TFGPEREAEPAKEAR	NISCH	6	Q9Y2I1
FPEGPAVAVRLSKDR	TMPRSS4	96	Q9NRS4
RDFKRLQEDPPAGVS	UBE2A	11	P49459
APKELSFGARAELPR	UMPS	221	P11172
ETRAAGKRPAEDDIP	TCEAL2	121	Q9H3H9
LAAGADSPKTEEARP	TBC1D10B	126	Q4KMP7
PKRSRPTSFADELAA	WASHC2C	281	Q9Y4E1
KSGLPNDRFSAERPE	TRBV7-6	76	A0A1B0GX31
EAQPDKSGLPSDRFS	TRBV7-7	71	A0A0K0K1E9
KSGLPSDRFSAERPE	TRBV7-7	76	A0A0K0K1E9
APSPEARDSKEDGRK	SAFB2	341	Q14151
PPDSLEAAEAGIRKF	SPTB	1196	P11277
DELFARSSDPRSPKG	USP9Y	206	O00507
SRKVAEETPDGAPAL	PRKX	16	P51817
DVSGSEDTFPNKRPR	SPRTN	396	Q9H040
ATAPSKDPDRGFRRD	SEC16B	16	Q96JE7
PKRSRPTSFADELAA	WASHC2A	281	Q641Q2
SPGRRKRDTNAPESF	TRIP11	1891	Q15643
GVDPTSRFKQDPDSR	ZNF608	1226	Q9ULD9
PFDDSDIAGLPRRQK	TSSK6	211	Q9BXA6
EDEPGLPRKADFSAV	PHLPP1	1601	O60346
PEDVSFAESRRDGLK	TBCD	806	Q9BTW9
EPAEAPATRRELFSG	PLEKHG2	701	Q9H7P9
RAPLDDSGMPKDRFS	TRBV12-5	71	A0A1B0GX78
DSKPEPDKVGRFASR	ZBTB38	756	Q8NAP3
DGAARTPKVNPFSAR	TESK2	391	Q96S53
DATGDLDANRPVPFR	TRRAP	3716	Q9Y4A5
KRPRKDENESSAPAD	TERF2	371	Q15554
RDFKRLQEDPPVGVS	UBE2B	11	P63146
KSGLPSDRFFAERPE	TRBV7-8	76	A0A1B0GX51
SRGIKDFENDPPLSS	UBASH3A	441	P57075
KKAPRRPQSDDDGEA	ZAR1	231	Q86SH2
DGERPPKLEFADNRI	WNK3	1096	Q9BYP7
APRENEKPFIDSERA	NALF1	21	B1AL88
SREGNARPIFFTPKD	MYO9A	1661	B2RTY4
ARRFSSGLFNKPEEP	PPP1R12B	416	O60237