Cluster composition

Functions

CategoryNameIntersectionWithQueryPValueGenesInTermGenesInQueryGenesInTermInQueryID
GeneOntologyMolecularFunctionATP-dependent activity

SPAST ABCA13 ABCB5 INO80 ATP8B2 DHX8 ABCB1 DDX11 BPTF MFSD2A UBA1 KIF15 DYNLRB1 DDX53 DDX43 ATP2B2 ATP2B4

6.43e-0861411317GO:0140657
GeneOntologyMolecularFunctionATP hydrolysis activity

SPAST ABCA13 ABCB5 INO80 ATP8B2 DHX8 ABCB1 DDX11 KIF15 DDX53 DDX43 ATP2B2 ATP2B4

1.29e-0644111313GO:0016887
GeneOntologyMolecularFunctionactive transmembrane transporter activity

ABCA13 SLC26A4 ABCB5 SLCO3A1 SLC1A2 NDUFV1 ABCB1 MFSD2A SLC15A1 SLC7A5 SLC23A2 ATP2B2 ATP2B4

3.06e-0647711313GO:0022804
GeneOntologyMolecularFunctiontransporter activity

ABCA13 SLC26A4 ABCB5 SLC19A2 MFSD9 SLCO3A1 AQP1 SLC1A2 ATP8B2 NDUFV1 GGA3 ABCB1 MFSD2A GSDME SLC15A1 SLC7A5 CACNA1G SLC23A2 ATP2B2 ATP2B4

3.38e-05128911320GO:0005215
GeneOntologyMolecularFunctionglycerophospholipid flippase activity

ATP8B2 ABCB1 MFSD2A

6.14e-05141133GO:0140333
GeneOntologyMolecularFunctiontransmembrane transporter activity

ABCA13 SLC26A4 ABCB5 SLC19A2 MFSD9 SLCO3A1 AQP1 SLC1A2 NDUFV1 ABCB1 MFSD2A GSDME SLC15A1 SLC7A5 CACNA1G SLC23A2 ATP2B2 ATP2B4

1.09e-04118011318GO:0022857
GeneOntologyMolecularFunctionflippase activity

ATP8B2 ABCB1 MFSD2A

1.13e-04171133GO:0140327
GeneOntologyMolecularFunctionribonucleoside triphosphate phosphatase activity

SPAST ABCA13 ABCB5 INO80 ATP8B2 TRIM23 DHX8 ABCB1 DDX11 KIF15 DDX53 DDX43 ATP2B2 ATP2B4

1.22e-0477511314GO:0017111
GeneOntologyMolecularFunction4 iron, 4 sulfur cluster binding

ACO1 NDUFV1 DDX11 MOCS1

1.44e-04471134GO:0051539
GeneOntologyMolecularFunctioncarboxylic acid transmembrane transporter activity

SLC26A4 SLC19A2 SLC1A2 ABCB1 MFSD2A SLC7A5 SLC23A2

1.77e-042071137GO:0046943
GeneOntologyMolecularFunctionorganic acid transmembrane transporter activity

SLC26A4 SLC19A2 SLC1A2 ABCB1 MFSD2A SLC7A5 SLC23A2

1.83e-042081137GO:0005342
GeneOntologyMolecularFunctionorganic anion transmembrane transporter activity

SLC26A4 SLC19A2 SLCO3A1 SLC1A2 ABCB1 MFSD2A SLC7A5 SLC23A2

2.64e-042931138GO:0008514
GeneOntologyMolecularFunctionpyrophosphatase activity

SPAST ABCA13 ABCB5 INO80 ATP8B2 TRIM23 DHX8 ABCB1 DDX11 KIF15 DDX53 DDX43 ATP2B2 ATP2B4

2.77e-0483911314GO:0016462
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides

SPAST ABCA13 ABCB5 INO80 ATP8B2 TRIM23 DHX8 ABCB1 DDX11 KIF15 DDX53 DDX43 ATP2B2 ATP2B4

2.80e-0484011314GO:0016817
GeneOntologyMolecularFunctionhydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

SPAST ABCA13 ABCB5 INO80 ATP8B2 TRIM23 DHX8 ABCB1 DDX11 KIF15 DDX53 DDX43 ATP2B2 ATP2B4

2.80e-0484011314GO:0016818
GeneOntologyMolecularFunctionactive monoatomic ion transmembrane transporter activity

SLC26A4 SLC1A2 NDUFV1 MFSD2A SLC15A1 SLC23A2 ATP2B2 ATP2B4

3.16e-043011138GO:0022853
GeneOntologyMolecularFunctionATPase-coupled transmembrane transporter activity

ABCA13 ABCB5 ABCB1 ATP2B2 ATP2B4

3.89e-041091135GO:0042626
GeneOntologyMolecularFunctionATPase-coupled intramembrane lipid transporter activity

ATP8B2 ABCB1 MFSD2A

5.21e-04281133GO:0140326
GeneOntologyMolecularFunctionprimary active transmembrane transporter activity

ABCA13 ABCB5 NDUFV1 ABCB1 ATP2B2 ATP2B4

5.30e-041781136GO:0015399
GeneOntologyMolecularFunctionphosphatidylcholine floppase activity

ATP8B2 ABCB1

8.69e-0481132GO:0090554
GeneOntologyMolecularFunctioniron-sulfur cluster binding

ACO1 NDUFV1 DDX11 MOCS1

1.00e-03781134GO:0051536
GeneOntologyMolecularFunctionATP-dependent activity, acting on RNA

DHX8 DDX11 DDX53 DDX43

1.10e-03801134GO:0008186
GeneOntologyMolecularFunctionmetal cluster binding

ACO1 NDUFV1 DDX11 MOCS1

1.27e-03831134GO:0051540
GeneOntologyMolecularFunctionsecondary active transmembrane transporter activity

SLC26A4 SLCO3A1 SLC1A2 MFSD2A SLC15A1 SLC7A5 SLC23A2

1.48e-032961137GO:0015291
GeneOntologyMolecularFunctionP-type calcium transporter activity

ATP2B2 ATP2B4

1.69e-03111132GO:0005388
GeneOntologyBiologicalProcesstransport across blood-brain barrier

SLCO3A1 SLC1A2 ABCB1 MFSD2A SLC7A5 ATP2B4

7.13e-06871106GO:0150104
GeneOntologyBiologicalProcessvascular transport

SLCO3A1 SLC1A2 ABCB1 MFSD2A SLC7A5 ATP2B4

7.62e-06881106GO:0010232
GeneOntologyCellularComponentbasal part of cell

EPPK1 SLCO3A1 ITGA2 AQP1 NEDD9 SLC7A5 SLC23A2 ATP2B2 ATP2B4

2.01e-043781129GO:0045178
GeneOntologyCellularComponentapical plasma membrane

SLC26A4 SLCO3A1 AQP1 ABCB1 SLC15A1 PKHD1 SLC7A5 PATJ SLC23A2 ATP2B2

2.91e-0448711210GO:0016324
GeneOntologyCellularComponentbasolateral plasma membrane

EPPK1 SLCO3A1 AQP1 NEDD9 SLC7A5 SLC23A2 ATP2B2 ATP2B4

3.31e-043201128GO:0016323
GeneOntologyCellularComponentexternal side of apical plasma membrane

ABCB1 SLC7A5

4.21e-0461122GO:0098591
GeneOntologyCellularComponentbasal plasma membrane

EPPK1 SLCO3A1 AQP1 NEDD9 SLC7A5 SLC23A2 ATP2B2 ATP2B4

6.44e-043541128GO:0009925
MousePhenoectopic Purkinje cell

PLXNB2 LYST CXCR4 ATM

2.67e-0526954MP:0000885
MousePhenoabsent distal visceral endoderm

INO80 BPTF

4.57e-052952MP:0012161
MousePhenothin cerebellar molecular layer

SLC25A46 CACNA1G ATM ATP2B2

4.79e-0530954MP:0000890
DomainBig_2

NUP210L NUP210

3.56e-0521122PF02368
DomainInvasin/intimin_cell_adhesion

NUP210L NUP210

3.56e-0521122IPR008964
DomainBID_2

NUP210L NUP210

3.56e-0521122SM00635
DomainBig_2

NUP210L NUP210

3.56e-0521122IPR003343
DomainATP_Ca_trans_C

ATP2B2 ATP2B4

2.12e-0441122IPR022141
DomainATP_Ca_trans_C

ATP2B2 ATP2B4

2.12e-0441122PF12424
DomainG8_domain

PKHD1L1 PKHD1

2.12e-0441122IPR019316
DomainG8

PKHD1L1 PKHD1

2.12e-0441122PS51484
DomainG8

PKHD1L1 PKHD1

2.12e-0441122SM01225
DomainG8

PKHD1L1 PKHD1

2.12e-0441122PF10162
DomainP-type_ATPase_IIB

ATP2B2 ATP2B4

2.12e-0441122IPR006408
DomainPbH1

PKHD1L1 PKHD1

5.26e-0461122SM00710
DomainPbH1

PKHD1L1 PKHD1

5.26e-0461122IPR006626
DomainIPT

PLXNB2 PKHD1L1 PKHD1

5.53e-04271123SM00429
DomainTIG

PLXNB2 PKHD1L1 PKHD1

8.35e-04311123PF01833
DomainIPT

PLXNB2 PKHD1L1 PKHD1

9.17e-04321123IPR002909
DomainPectin_lyase_fold/virulence

PKHD1L1 PKHD1

9.75e-0481122IPR011050
DomainS1

POLR2G DHX8

9.75e-0481122PF00575
DomainATPase_P-typ_cyto_domN

ATP8B2 ATP2B2 ATP2B4

1.19e-03351123IPR023299
DomainMFS_dom

SLC19A2 MFSD9 SLCO3A1 MFSD2A SLC15A1

1.28e-031341125IPR020846
DomainATPase_P-typ_P_site

ATP8B2 ATP2B2 ATP2B4

1.30e-03361123IPR018303
DomainP_typ_ATPase

ATP8B2 ATP2B2 ATP2B4

1.30e-03361123IPR001757
DomainATPASE_E1_E2

ATP8B2 ATP2B2 ATP2B4

1.30e-03361123PS00154
DomainATPase_P-typ_transduc_dom_A

ATP8B2 ATP2B2 ATP2B4

1.41e-03371123IPR008250
DomainE1-E2_ATPase

ATP8B2 ATP2B2 ATP2B4

1.41e-03371123PF00122
DomainP-loop_NTPase

SPAST ABCA13 ABCB5 INO80 TRIM23 DHX8 ABCB1 DDX11 KIF15 SMG9 DDX53 DDX43 CARD14

1.70e-0384811213IPR027417
Domain-

SPAST ABCA13 ABCB5 INO80 TRIM23 DHX8 ABCB1 DDX11 SMG9 DDX53 DDX43 CARD14

1.73e-03746112123.40.50.300
DomainS1

POLR2G DHX8

2.26e-03121122SM00316
DomainS1_dom

POLR2G DHX8

2.26e-03121122IPR022967
DomainS1_domain

POLR2G DHX8

2.26e-03121122IPR003029
DomainABC_tran

ABCA13 ABCB5 ABCB1

2.98e-03481123PF00005
DomainABC_TRANSPORTER_2

ABCA13 ABCB5 ABCB1

2.98e-03481123PS50893
DomainABC_TRANSPORTER_1

ABCA13 ABCB5 ABCB1

3.16e-03491123PS00211
DomainABC_transporter-like

ABCA13 ABCB5 ABCB1

3.35e-03501123IPR003439
DomainHelicase_C

INO80 DHX8 DDX53 DDX43

3.94e-031071124PF00271
DomainHELICc

INO80 DHX8 DDX53 DDX43

3.94e-031071124SM00490
DomainADH_SHORT

PECR HSD17B12 SDR16C5

3.95e-03531123PS00061
DomainATPase_P-typ_TM_dom

ATP2B2 ATP2B4

4.05e-03161122IPR023298
Domain-

ATP2B2 ATP2B4

4.05e-031611221.20.1110.10
DomainHelicase_C

INO80 DHX8 DDX53 DDX43

4.07e-031081124IPR001650
DomainHELICASE_CTER

INO80 DHX8 DDX53 DDX43

4.21e-031091124PS51194
DomainHELICASE_ATP_BIND_1

INO80 DHX8 DDX53 DDX43

4.21e-031091124PS51192
DomainDEXDc

INO80 DHX8 DDX53 DDX43

4.21e-031091124SM00487
DomainHelicase_ATP-bd

INO80 DHX8 DDX53 DDX43

4.34e-031101124IPR014001
Domainadh_short

PECR HSD17B12 SDR16C5

4.39e-03551123PF00106
DomainATPase_P-typ_cation-transptr_C

ATP2B2 ATP2B4

4.57e-03171122IPR006068
DomainCation_ATPase_C

ATP2B2 ATP2B4

4.57e-03171122PF00689
DomainSDR_fam

PECR HSD17B12 SDR16C5

4.62e-03561123IPR002347
DomainCation_ATPase_N

ATP2B2 ATP2B4

5.12e-03181122PF00690
DomainCation_ATPase_N

ATP2B2 ATP2B4

5.12e-03181122SM00831
DomainATPase_P-typ_cation-transptr_N

ATP2B2 ATP2B4

5.70e-03191122IPR004014
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

DERL1 ACO1 SLC26A4 ABCB5 PSMB3 SLCO3A1 PSMD5 AQP1 SLC1A2 ATP8B2 ABCB1 SLC15A1 SLC7A5 ATP2B2 ATP2B4

1.85e-056818815MM14985
PathwayREACTOME_TRANSPORT_OF_SMALL_MOLECULES

DERL1 ACO1 SLC26A4 ABCB5 PSMB3 SLCO3A1 PSMD5 AQP1 SLC1A2 ATP8B2 ABCB1 SLC15A1 SLC7A5 ATP2B2 ATP2B4

4.55e-057368815M27287
Pubmed

A dual-activity topoisomerase complex regulates mRNA translation and turnover.

EPPK1 NRF1 PHF12 DOCK9 HECTD4 KDM3B PIGG INO80 PLXNB2 LYST GGA3 SCAP ZNF341 NAPRT SLC7A5 DOT1L

5.98e-0711051131635748872
Pubmed

Large-scale proteomics and phosphoproteomics of urinary exosomes.

SPAST NRF1 ACO1 SLC26A4 PSMB3 PFKL AQP1 ABCB1 UBA1 NAPRT UGP2 PKHD1 CD63 EIF3H PATJ

1.09e-0610161131519056867
Pubmed

Blood-Brain Barrier: From Physiology to Disease and Back.

SLCO3A1 SLC1A2 ABCB1 MFSD2A SLC7A5 ATP2B4

1.27e-06105113630280653
Pubmed

Genomic structure and chromosomal localization of the mouse gene Punc.

IGDCC3 IGDCC4

1.05e-05211329922388
Pubmed

Decreased expression of BRCA1 in SK-BR-3 cells is the result of aberrant activation of the GABP Beta promoter by an NRF-1-containing complex.

NRF1 GABPB1

1.05e-052113221609478
Pubmed

The longevity-associated variant of BPIFB4 improves a CXCR4-mediated striatum-microglia crosstalk preventing disease progression in a mouse model of Huntington's disease.

CXCR4 BPIFB4

1.05e-052113232683420
Pubmed

Microdiversity of human-plasma-membrane calcium-pump isoform 2 generated by alternative RNA splicing in the N-terminal coding region.

ATP2B2 ATP2B4

1.05e-05211321313367
Pubmed

Plasma membrane calcium pump (PMCA) isoform 4 is targeted to the apical membrane by the w-splice insert from PMCA2.

ATP2B2 ATP2B4

1.05e-052113222252018
Pubmed

Plasma membrane Ca²⁺-ATPases can shape the pattern of Ca²⁺ transients induced by store-operated Ca²⁺ entry.

ATP2B2 ATP2B4

1.05e-052113225690014
Pubmed

The expression of the BPIFB4 and CXCR4 associates with sustained health in long-living individuals from Cilento-Italy.

CXCR4 BPIFB4

1.05e-052113228121621
Pubmed

ATM is activated by ATP depletion and modulates mitochondrial function through NRF1.

NRF1 ATM

1.05e-052113230642892
Pubmed

The clinical relevance and prognostic significance of adenosine triphosphate ATP-binding cassette (ABCB5) and multidrug resistance (MDR1) genes expression in acute leukemia: an Egyptian study.

ABCB5 ABCB1

1.05e-052113224804815
Pubmed

The helicase HAGE expressed by malignant melanoma-initiating cells is required for tumor cell proliferation in vivo.

ABCB5 DDX43

1.05e-052113222393060
Pubmed

A CD63 mutant inhibits T-cell tropic human immunodeficiency virus type 1 entry by disrupting CXCR4 trafficking to the plasma membrane.

CXCR4 CD63

1.05e-052113218182005
Pubmed

Plasma membrane calcium-ATPase 2 and 4 in human breast cancer cell lines.

ATP2B2 ATP2B4

1.05e-052113216216224
Pubmed

DNA methylation profiling in doxorubicin treated primary locally advanced breast tumours identifies novel genes associated with survival and treatment response.

ABCB1 CXCR4 ATM

1.18e-0514113320338046
Pubmed

Establishment and Dysfunction of the Blood-Brain Barrier.

SLC1A2 ABCB1 MFSD2A SLC7A5

2.54e-0552113426590417
Pubmed

Genetic architecture of human thinness compared to severe obesity.

ILRUN PKHD1

3.13e-053113230677029
Pubmed

Isolation and characterization of the mouse Aire gene.

AIRE PFKL

3.13e-053113210049735
Pubmed

Intracellular expression of P-170 glycoprotein in peripheral blood mononuclear cell subsets from healthy donors and HIV-infected patients.

ABCB5 ABCB1

3.13e-05311329542318
Pubmed

The helicase HAGE prevents interferon-α-induced PML expression in ABCB5+ malignant melanoma-initiating cells by promoting the expression of SOCS1.

ABCB5 DDX43

3.13e-053113224525737
Pubmed

The interaction between endogenous calcineurin and the plasma membrane calcium-dependent ATPase is isoform specific in breast cancer cells.

ATP2B2 ATP2B4

3.13e-053113217689535
Pubmed

Endothelial nitric oxide synthase activity is inhibited by the plasma membrane calcium ATPase in human endothelial cells.

ATP2B2 ATP2B4

3.13e-053113220211863
Pubmed

The mouse Aire gene: comparative genomic sequencing, gene organization, and expression.

AIRE PFKL

3.13e-053113210022980
Pubmed

Quantitative targeted absolute proteomic analysis of transporters, receptors and junction proteins for validation of human cerebral microvascular endothelial cell line hCMEC/D3 as a human blood-brain barrier model.

ABCB1 SLC15A1 SLC7A5

4.26e-0521113323137377
Pubmed

MECP2 directly interacts with RNA polymerase II to modulate transcription in human neurons.

DERL1 POLR2G HECTD4 SEC31A INO80 NDUFV1 DHX8 BPTF MAMDC2 HSD17B12 TAF15 ATM PBXIP1

5.16e-0510821131338697112
Pubmed

∆F508 CFTR interactome remodelling promotes rescue of cystic fibrosis.

EPPK1 DERL1 PSMB3 ITGA2 PFKL UBA1 NUP210 HSD17B12 UBR3 ATP2B4

5.16e-056471131026618866
Pubmed

LMBR1L regulates lymphopoiesis through Wnt/β-catenin signaling.

DERL1 SLC19A2 SEC31A PLXNB2 RNF115 NDUFV1 PGM3 SCAP NUP210 HSD17B12 RHBDD3 ATP2B4

5.86e-059421131231073040
Pubmed

Cell-specific expression of plasma membrane calcium ATPase isoforms in retinal neurons.

ATP2B2 ATP2B4

6.25e-054113212209837
Pubmed

Expression and role of calcium-ATPase pump and sodium-calcium exchanger in differentiated trophoblasts from human term placenta.

ATP2B2 ATP2B4

6.25e-054113212784250
Pubmed

Pharmacogenetics of antiepileptic drug efficacy in childhood absence epilepsy.

ABCB1 CACNA1G

6.25e-054113228165634
Pubmed

The plasma membrane calcium pump in health and disease.

ATP2B2 ATP2B4

6.25e-054113223413890
Pubmed

Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.

ATP2B2 ATP2B4

6.25e-05411328245032
Pubmed

Quantitative analysis of alternative splicing options of human plasma membrane calcium pump genes.

ATP2B2 ATP2B4

6.25e-05411327989379
Pubmed

Role of alternative splicing in generating isoform diversity among plasma membrane calcium pumps.

ATP2B2 ATP2B4

6.25e-054113211152753
Pubmed

Function and assembly of nuclear pore complex proteins.

NUP54 NUP210

6.25e-054113210546895
Pubmed

PMCA1 depletion in mouse eggs amplifies calcium signaling and impacts offspring growth†.

ATP2B2 ATP2B4

6.25e-054113236130203
Pubmed

Developmental expression of the four plasma membrane calcium ATPase (Pmca) genes in the mouse.

ATP2B2 ATP2B4

6.25e-054113210434059
Pubmed

The Organic Anion-Transporting Peptide 2B1 Is Localized in the Basolateral Membrane of the Human Jejunum and Caco-2 Monolayers.

ABCB1 SLC15A1

6.25e-054113228408210
Pubmed

The human AIRE gene at chromosome 21q22 is a genetic determinant for the predisposition to rheumatoid arthritis in Japanese population.

AIRE PFKL

6.25e-054113221505073
Pubmed

Calcium pumps of plasma membrane and cell interior.

ATP2B2 ATP2B4

6.25e-054113215101689
Pubmed

Plasma membrane calcium ATPases as critical regulators of calcium homeostasis during neuronal cell function.

ATP2B2 ATP2B4

6.25e-054113210577388
Pubmed

Structural organization, ion transport, and energy transduction of P-type ATPases.

ATP2B2 ATP2B4

6.25e-05411328634322
Pubmed

Cloning and expression of nope, a new mouse gene of the immunoglobulin superfamily related to guidance receptors.

IGDCC3 IGDCC4

6.25e-054113210708514
Pubmed

The N6-methyladenosine-mediated lncRNA WEE2-AS1 promotes glioblastoma progression by stabilizing RPN2.

ACO1 GPAT3 PSMD5 GSDME EGR2 SLC7A5 ATP2B4

9.66e-05325113736168628
Pubmed

Expression of aquaporin 1 and 5 in the developing mouse inner ear and audiovestibular assessment of an Aqp5 null mutant.

SLC26A4 AQP1

1.04e-045113212943377
Pubmed

Aire-dependent production of XCL1 mediates medullary accumulation of thymic dendritic cells and contributes to regulatory T cell development.

AIRE CXCR4

1.04e-045113221300913
Pubmed

Distinct roles of ATM and ATR in the regulation of ARP8 phosphorylation to prevent chromosome translocations.

INO80 ATM

1.04e-045113229759113
Pubmed

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence.

PKHD1L1 PKHD1

1.04e-045113220048263
Pubmed

Differential regulation of the apical plasma membrane Ca(2+) -ATPase by protein kinase A in parotid acinar cells.

ATP2B2 ATP2B4

1.04e-045113217938178
Pubmed

Molecular cloning of a novel type 1 cytokine receptor similar to the common gamma chain.

CRLF2 FGF5

1.04e-045113210733486
Pubmed

CXCR4 expression on activated B cells is downregulated by CD63 and IL-21.

CXCR4 CD63

1.04e-045113221270405
Pubmed

An empirical framework for binary interactome mapping.

DBF4B AQP1 TRIM23 EIF3H PBXIP1 GABPB1

1.12e-04231113619060904
Pubmed

Biology, structure and mechanism of P-type ATPases.

ATP8B2 ATP2B2 ATP2B4

1.15e-0429113315071553
Pubmed

FAM105A/OTULINL Is a Pseudodeubiquitinase of the OTU-Class that Localizes to the ER Membrane.

DERL1 GPAT3 ITGA2 PLXNB2 SCAP NUP210 HSD17B12 PBXIP1

1.51e-04468113831056421
Pubmed

Characterization of PISP, a novel single-PDZ protein that binds to all plasma membrane Ca2+-ATPase b-splice variants.

ATP2B2 ATP2B4

1.56e-046113212763866
Pubmed

Cardiac excitation-contraction coupling in the absence of Na(+) - Ca2+ exchange.

ATP2B2 ATP2B4

1.56e-046113212767889
Pubmed

Nfkb2 variants reveal a p100-degradation threshold that defines autoimmune susceptibility.

HLA-DQA2 AIRE

1.56e-046113233107914
Pubmed

Cytoplasmic domains of the transporter associated with antigen processing and P-glycoprotein interact with subunits of the proteasome.

ABCB5 ABCB1

1.56e-046113215488952
Pubmed

Plasma membrane Ca2+-atpase isoforms 2b and 4b interact promiscuously and selectively with members of the membrane-associated guanylate kinase family of PDZ (PSD95/Dlg/ZO-1) domain-containing proteins.

ATP2B2 ATP2B4

1.56e-046113211274188
Pubmed

Mice deficient in MCT8 reveal a mechanism regulating thyroid hormone secretion.

SLCO3A1 SLC7A5

1.56e-046113220679730
Pubmed

Endogenous Cell Type-Specific Disrupted in Schizophrenia 1 Interactomes Reveal Protein Networks Associated With Neurodevelopmental Disorders.

POLD2 PFKL PGM3 NUP210 PBXIP1

1.62e-04156113529961565
Pubmed

An Interaction Landscape of Ubiquitin Signaling.

DERL1 HECTD4 KDM3B PSMD5 GGA3 UBA1 KIF15 SLC7A5

1.82e-04481113828190767
Pubmed

An investigation into the human serum "interactome".

SPAST DERL1 ITGA2 IGDCC4 ATM

1.93e-04162113515174051
Pubmed

Basophils promote barrier dysfunction and resolution in the atopic skin.

HLA-DQA2 CRLF2

2.17e-047113233662369
Pubmed

Arf4 is required for Mammalian development but dispensable for ciliary assembly.

PKHD1L1 PKHD1

2.17e-047113224586199
Pubmed

A small-molecule inhibitor and degrader of the RNF5 ubiquitin ligase.

DERL1 UBA1

2.17e-047113236074076
Pubmed

Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.

SLC1A2 ITIH3 IGDCC4 PTPRN CD63 HSD17B12 SEZ6

2.36e-04376113724154525
Pubmed

Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.

ACO1 PFKL PGM3 UGP2

2.47e-0493113427215380
Pubmed

In-Depth In Vivo Crosslinking in Minutes by a Compact, Membrane-Permeable, and Alkynyl-Enrichable Crosslinker.

ABCB5 LYST ABCB1 NUP54 DDX11 BPTF NRXN3 NSA2 UGP2 PKHD1 SLC7A5 TAF15 ATM ATP2B2

2.47e-0414421131435575683
Pubmed

Maternal Transient Receptor Potential Vanilloid 6 (Trpv6) Is Involved In Offspring Bone Development.

CACNA1G ATP2B2 ATP2B4

2.59e-0438113330786075
Pubmed

Activity-based E3 ligase profiling uncovers an E3 ligase with esterification activity.

HECTD4 TRIM23 UBA1 UBR3

2.68e-0495113429643511
Pubmed

FTY720-enhanced T cell homing is dependent on CCR2, CCR5, CCR7, and CXCR4: evidence for distinct chemokine compartments.

ABCB1 CXCR4

2.89e-048113215240672
Pubmed

NRXN3 is a novel locus for waist circumference: a genome-wide association study from the CHARGE Consortium.

NRXN3 PKHD1

2.89e-048113219557197
Pubmed

Gene knockout studies of Ca2+-transporting ATPases.

ATP2B2 ATP2B4

2.89e-048113210951186
Pubmed

Live cell imaging of the HIV-1 life cycle.

CXCR4 CD63

2.89e-048113218977142
Pubmed

Systematically defining selective autophagy receptor-specific cargo using autophagosome content profiling.

EPPK1 POLD2 KDM3B SEC31A PIGG PLXNB2 NDUFV1 BPTF UBA1 NAPRT NUP210 CD63 HSD17B12

3.08e-0412971131333545068
Pubmed

Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

SPAST PHF12 HECTD4 KDM3B INO80 GGA3 NRXN3 CACNA1G

3.44e-04529113814621295
Pubmed

Transcriptomic and quantitative proteomic analysis of transporters and drug metabolizing enzymes in freshly isolated human brain microvessels.

SLC1A2 ABCB1

3.71e-049113221707071
Pubmed

The expression of thyroid hormone transporters in the human fetal cerebral cortex during early development and in N-Tera-2 neurodifferentiation.

SLCO3A1 SLC7A5

3.71e-049113221486766
Pubmed

Multiple renal cysts, urinary concentration defects, and pulmonary emphysematous changes in mice lacking TAZ.

AQP1 PKHD1

3.71e-049113218172001
Pubmed

Members of the Zyxin family of LIM proteins interact with members of the p130Cas family of signal transducers.

NEDD9 NUP210

3.71e-049113211782456
Pubmed

A Role for Mitochondrial Translation in Promotion of Viability in K-Ras Mutant Cells.

PSMB3 POLR2G GGA3 NRXN3 SCAP DYNLRB1 GABPB1

4.52e-04419113728700943
Pubmed

EWS, but not EWS-FLI-1, is associated with both TFIID and RNA polymerase II: interactions between two members of the TET family, EWS and hTAFII68, and subunits of TFIID and RNA polymerase II complexes.

POLR2G TAF15

4.63e-041011329488465
Pubmed

Screening of Hsp105alpha-binding proteins using yeast and bacterial two-hybrid systems.

UBA1 DYNLRB1

4.63e-0410113214733918
Pubmed

Proteome-scale mapping of binding sites in the unstructured regions of the human proteome.

EPPK1 RNF115 GGA3 NEDD9 EGR2 ATM PATJ

5.28e-04430113735044719
Pubmed

RSPO-LGR4 functions via IQGAP1 to potentiate Wnt signaling.

PIGG NUP210 PKHD1 SLC7A5 ATP2B2

5.31e-04202113524639526
Pubmed

ESCPE-1 mediates retrograde endosomal sorting of the SARS-CoV-2 host factor Neuropilin-1.

ERO1B PIGG ITGA2 PLXNB2 UBA1 SCAP CXCR4 NUP210 DYNLRB1 SLC7A5 ATM PBXIP1

5.45e-0412011131235696571
Pubmed

Chemokine Signaling Controls Integrity of Radial Glial Scaffold in Developing Spinal Cord and Consequential Proper Position of Boundary Cap Cells.

EGR2 CXCR4

5.65e-0411113226085643
Pubmed

Subcellular localization of transporters along the rat blood-brain barrier and blood-cerebral-spinal fluid barrier by in vivo biotinylation.

ABCB1 SLC7A5

5.65e-0411113218619525
Pubmed

ADAM-mediated ectodomain shedding of HB-EGF in receptor cross-talk.

ITGA2 CD63

5.65e-0411113216054021
Pubmed

A comparison of whole-genome shotgun-derived mouse chromosome 16 and the human genome.

BPTF NRXN3 NSA2 BPIFB4 UBR3

5.68e-04205113512040188
Pubmed

A BioID-Derived Proximity Interactome for SARS-CoV-2 Proteins.

SEC31A PIGG SOCS6 PLXNB2 TBC1D8 CD63 SLC7A5 SLC23A2 ATP2B4

5.80e-04719113935337019
Pubmed

Voltage-dependent conformational changes of Kv1.3 channels activate cell proliferation.

EPPK1 ABCA13 YEATS2 UBA1 PKHD1

6.06e-04208113533230847
Pubmed

Quantitative dissection and stoichiometry determination of the human SET1/MLL histone methyltransferase complexes.

INO80 YEATS2 BPTF TAF15

6.29e-04119113423508102
Pubmed

An antibody-based proximity labeling map reveals mechanisms of SARS-CoV-2 inhibition of antiviral immunity.

GPAT3 KDM3B MFSD9 DHX8 YEATS2 SCAP SMG9 SLC7A5 PATJ

6.65e-04733113934672954
Pubmed

Multilevel proteomics reveals host perturbations by SARS-CoV-2 and SARS-CoV.

ACO1 SLC19A2 SEC31A ATP8B2 KIAA0319 TBC1D8 SCAP RHBDD3 ATM SLC23A2 ATP2B4

6.92e-0410611131133845483
Pubmed

Accelerating functional gene discovery in osteoarthritis.

GSDME ZNF341 SMG9

6.95e-0453113333473114
Pubmed

Quantitative interaction proteomics and genome-wide profiling of epigenetic histone marks and their readers.

PHF12 YEATS2 BPTF TAF15

7.34e-04124113420850016
Pubmed

The MYO6 interactome reveals adaptor complexes coordinating early endosome and cytoskeletal dynamics.

DOCK9 GGA3 YEATS2 ATP2B4

7.57e-04125113429467281
InteractionAVPR2 interactions

SLC25A46 DERL1 SLC19A2 ATP8B2 ATM ATP2B2 ATP2B4

5.34e-061231117int:AVPR2
InteractionCCR6 interactions

SLC19A2 PIGG ATP8B2 ABCB1 ATP2B2 ATP2B4

9.77e-06891116int:CCR6
InteractionFPR2 interactions

DERL1 SLC19A2 GPAT3 PIGG CD63 ATP2B2 ATP2B4

1.14e-051381117int:FPR2
InteractionHTR3A interactions

PIGG ATP8B2 SCAP RHBDD3 ATP2B2 ATP2B4

2.96e-051081116int:HTR3A
InteractionNIPAL1 interactions

SLC19A2 GPAT3 MFSD9 CXCR4 ATP2B2 ATP2B4

4.01e-051141116int:NIPAL1
GeneFamilySolute carriers

SLC25A46 SLC26A4 SLC19A2 SLCO3A1 SLC1A2 SLC15A1 SLC7A5 SLC23A2

5.37e-04395858752
GeneFamilyATPases Ca2+ transporting

ATP2B2 ATP2B4

7.70e-0498521209
GeneFamilyDEAD-box helicases

DDX11 DDX53 DDX43

1.01e-0342853499
GeneFamilyATP binding cassette subfamily B

ABCB5 ABCB1

1.17e-0311852806
GeneFamilyRhomboid family

DERL1 RHBDD3

1.92e-0314852926
GeneFamilyDNA helicases

INO80 DDX11

2.84e-03178521167
CoexpressionACEVEDO_LIVER_CANCER_WITH_H3K9ME3_UP

ABCA13 FAT3 ABCB5 CRLF2 NRXN3 SERPINB4 PKHD1

2.45e-061391137M6754
ToppCellfacs-Diaphragm-Limb_Muscle-24m|Diaphragm / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ABCA13 FAT3 PKHD1L1 NRXN3 PKHD1 CD63 ATP2B2

2.57e-07169113712bdc709bc000d7f9061ecd9fbd57233eaacb7e2
ToppCellrenal_medulla_nuclei-Adult_normal_reference-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Adult_normal_reference / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 SLCO3A1 AQP1 ABCB1 NEDD9 PKHD1

4.09e-0718111376956ecd6264f7469a25e555673bce4eb97d28f7a
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D175|Adult / Lineage, Cell type, age group and donor

EPPK1 ABCA13 DOCK9 INO80 MFSD2A NRXN3 SDR16C5

5.29e-071881137ec38def1fdbb34ed9b30244806975bd5a4370164
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B GPAT3 KDM3B NUP54 NEDD9 CXCR4

4.20e-0616611366a948aefd283a2572da37b59dbc142b6e686b024
ToppCellfacs-Kidney-nan-3m-Lymphocytic-B_cell|Kidney / Skin_Bladder_Kidney_Mammary_Gland - method, tissue, subtissue, age, lineage, cell ontology and free annotation

ERO1B GPAT3 KDM3B NUP54 NEDD9 CXCR4

4.20e-0616611368d0c4eb90a2c006f96ae61d3d94c96fb64bc0c4d
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_late|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CAPNS2 ITGA2 NRXN3 DUOXA1 EGR2 SDR16C5

6.68e-061801136255097d8eb244a32eb2ecd0e7e48e1a20bafb5cd
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SLCO3A1 AQP1 ABCB1 NEDD9 PKHD1

7.12e-0618211365e1b316599436740f1b30875f0ebd33c3edfb2b6
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 SLCO3A1 AQP1 ABCB1 NEDD9 PKHD1

8.06e-0618611365c4ffe4e4d5536ae9f8794277fe032c693e7dd56
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 MFSD2A NUP210 PKHD1 PATJ

8.06e-061861136bb0bfe9a015151be08a6ffc5d82896d0556d76de
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma-6|TCGA-Skin / Sample_Type by Project: Shred V9

EPPK1 CAPNS2 DUOXA1 SLC15A1 SERPINB4 SDR16C5

8.31e-0618711362ca7928baf0c5e61f7294ed05e6e6f0e0adf9d3f
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 NRXN3 NUP210 PKHD1 PATJ

9.10e-061901136625c08a0e5227efc46daa512fd579c3938ff76c7
ToppCellPCW_07-8.5-Epithelial-Epithelial_alveolar-distal|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 NRXN3 NUP210 PKHD1 PATJ

9.66e-061921136b7c01e12b3e9be960a741b08835f1dfff65d0d47
ToppCellILEUM-inflamed-(3)_mature_DC|inflamed / shred on tissue, inflammation_status, cell class(v3), cell subclass (v2)

HLA-DQA2 SLC1A2 LYST CRLF2 TBC1D8 CXCR4

1.02e-051941136369bbf4e8e2d674e5a51a614b52b97d05d3ab9c7
ToppCellLPS_IL1RA-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_IL1RA / Treatment groups by lineage, cell group, cell type

ITGA2 NEDD9 NRXN3 PKHD1 DDX43 PATJ

1.12e-051971136b94645d57efe8d9e032bffb8c89af1f425c6421e
ToppCellhealthy_donor-Lymphocytic-T_cell-CD4+_Naive_T_cell|healthy_donor / Disease condition, Lineage, Cell class and subclass

EPPK1 DOCK9 ATP8B2 ATM PATJ PBXIP1

1.12e-051971136cf72160f03105876641fa6fdc7405e339eb084c7
ToppCellLPS_only-Epithelial_alveolar-AT_1-Differentiating_AT1|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA2 PLXNB2 NEDD9 NRXN3 PKHD1 PATJ

1.22e-0520011362dadf317a42a7e27cc1fac74f91b806c93a57108
ToppCellLPS_only-Epithelial_alveolar-AT_1|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA2 PLXNB2 NEDD9 NRXN3 PKHD1 PATJ

1.22e-0520011369a6ae40f3e17cd44ee5fd73260713b920aa2ea15
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_1-Fibcd1-Excitatory_Neuron.Slc17a7.Fibcd1-Fos_(CA1_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

NUP210L ABCB5 AIRE EGR2

2.00e-0563113422ab24281a42b60e79a6d35e25f42e7f20cb04b9
ToppCellControl-APC-like-Transitioning_MDM|Control / group, cell type (main and fine annotations)

HLA-DQA2 PSMB3 GPAT3 DYNLRB1 SLC7A5

3.22e-051431135ffc1f497245d559e97e40d1bc4ee14e1ef09040c
ToppCellHippocampus-Neuronal-Excitatory-eN3(Slc17a7_Gad1Gad2)|Hippocampus / BrainAtlas - Mouse McCarroll V32

SLC26A4 AIRE PKHD1L1 FGF5

4.43e-05771134a799ccdb84014e978d9fbccf3d2fee8fbeac7b0c
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT3 LYST NAPRT CD63 SSH2

5.03e-0515711358c42af7aa1f1b6f4fe2f8d00a8b4a800f121e804
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT3 LYST NAPRT CD63 SSH2

5.03e-051571135ee1be3c756b72fceac6b4ccb416dd4bd031a2193
ToppCellPND28-Immune-Immune_Myeloid-Granulocytic-Basophil-Basophil_mature|PND28 / Age_group by Lineage, Lineage_subclass, Cell_type, subtypes-by-prolif

FAT3 LYST NAPRT CD63 SSH2

5.03e-051571135008f938a338f43c3251dcac574f1b4f689926c71
ToppCellHippocampus-Neuronal-Excitatory-eN1(Slc17a7)-eN1_2-Pvrl3-Excitatory_Neuron.Slc17a7.Pvrl3-Fos_(CA3_Principal_cells)|Hippocampus / BrainAtlas - Mouse McCarroll V32

ABCB5 EGR2 FGF5 CARD14

5.15e-05801134b661644806e225f215047e78ae46d7cee6efde4f
ToppCelldroplet-Marrow-nan-21m-Lymphocytic-NK_cell|Marrow / Spleen_Marrow_Thymus - method, tissue, subtissue, age, lineage, cell ontology and free annotation

PTPRN CXCR4 CD63 SSH2 PBXIP1

7.54e-051711135355a27ea88410a84210f7e4298c7c4f90cf2f8a9
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 DUOXA1 SERPINB4 UGT2A1 SDR16C5

7.54e-05171113525c1979e972c959e1ce4c57804f976f53a247ad7
ToppCellcellseq2-Epithelial-Epithelial_Glandular-Goblet|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 DUOXA1 SERPINB4 UGT2A1 SDR16C5

7.54e-051711135fe27bf581c75ef33c2848878e51ed16b275a4c8e
ToppCellHealthy/Control-MAIT|World / Disease group and Cell class

ABCB1 CXCR4 SLC7A5 PATJ PBXIP1

7.54e-05171113561515114b17816a8f9ef6a57262eb9e977b6ede4
ToppCellHealthy/Control-MAIT|Healthy/Control / Disease group and Cell class

ABCB1 CXCR4 SLC7A5 PATJ PBXIP1

7.96e-05173113556247c1e07477a8922fe2e3950ae05e2217fd77c
ToppCellrenal_medulla_nuclei-Hypertensive_with+without-CKD-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Hypertensive_with+without-CKD / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 SLCO3A1 NEDD9 PKHD1

8.63e-051761135327a3e81b724252e36d786de92a3ffd721ea6d7b
ToppCellwk_20-22-Epithelial-Proximal_epithelial-basal_proximal|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

CAPNS2 NRXN3 DUOXA1 UGT2A1 SDR16C5

9.10e-0517811359534c4f4e950bb1498c1737ca1713e7f37d0aff2
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / V2 postpublication: Rhesus Genome Updated; Treatment groups by lineage, cell_type_level1, cell_type_level2

ITGA2 PLXNB2 MFSD2A NRXN3 PATJ

9.35e-051791135fd2cbee532e7b44113410dca82aec7db1a7fb69f
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_1/2_(AT1/AT2-like)-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA13 DOCK9 SLCO3A1 ITGA2 PATJ

9.85e-051811135576da14ab3107f89e1f44a4a439d1bef5bb42370
ToppCellfacs-Brain_Non-Myeloid-Cerebellum-3m-Epithelial-neuroepithelial_cell|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 CAPNS2 MFSD9 DUOXA1 SDR16C5

1.01e-0418211359174fb0b7ed8f721a5c513e41fd80476a9f34332
ToppCell3'-GW_trimst-1-SmallIntestine-Epithelial-neuro-epithelial-K_cells_(GIP+)|GW_trimst-1 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

ERO1B SLCO3A1 PTPRN NUP210 CARD14

1.04e-041831135d23018193b9c0806e0d1a9ac15e6392eb8e96aaf
ToppCelldroplet-Heart-4Chambers-18m-Neuronal-cardiac_neuron|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 FAT3 KIAA0319 PKHD1 PATJ

1.06e-0418411356388c47b7f1d8203e3069eba0e74107256dcae51
ToppCellwk_15-18-Epithelial-Proximal_epithelial-basal_proximal|wk_15-18 / Celltypes from embryonic and fetal-stage human lung

CAPNS2 ITGA2 NRXN3 UGT2A1 SDR16C5

1.06e-041841135575de705053da8b289670b5c40c1627c0833b5ed
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_1|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 SLCO3A1 NEDD9 PKHD1

1.06e-041841135da06ff24ee2b2cf4715fdfce43030b2da9e0aaf8
ToppCelldroplet-Heart-4Chambers-18m-Neuronal|Heart / Tongue_Heart_Limb_Muscle_Aorta_Diaphragm - method, tissue, subtissue, age, lineage, cell ontology and free annotation

EPPK1 FAT3 KIAA0319 PKHD1 PATJ

1.06e-041841135d83ae1dc64aa1b27d3b524c137567418cc0ff8c6
ToppCellPCW_05-06-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

HLA-DQA2 ITGA2 SLC1A2 PKHD1 PATJ

1.06e-041841135fa4915b0498f3069fd5ef497286445528f75187e
ToppCelldroplet-Lung-nan-21m-Endothelial-endothelial_cell_of_lymphatic_vessel|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 AQP1 PKHD1L1 NRXN3 CD63

1.09e-0418511353a4ae836e882e8d29eb0a2dfab5677f10f2d365f
ToppCellCOVID-19-Epithelial_cells-Airway_club|COVID-19 / group, cell type (main and fine annotations)

SLC26A4 DOCK9 NRXN3 DUOXA1 PATJ

1.09e-041851135cfe6fd73d817e173fe803bc1683c291d9bcb8608
ToppCelldroplet-Lung-nan-21m-Endothelial-Lymphatic_endothelial_cell|Lung / Lung_Trachea - method, tissue, subtissue, age, lineage, cell ontology and free annotation

DOCK9 AQP1 PKHD1L1 NRXN3 CD63

1.09e-041851135224f0b022c21dd40bf1f7503f00b3107ef958975
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D088|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

ABCA13 DOCK9 ITGA2 MFSD2A PATJ

1.12e-041861135acfa68a2afb7d2b51c9b469a1965fe5cc5d5e64e
ToppCellLV-10._Endothelium_II|World / Chamber and Cluster_Paper

DOCK9 AQP1 PKHD1L1 ABCB1 NEDD9

1.15e-0418711357876dcb4800c2e54874df3d933efb79307a64a97
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal-epi_SOX9^high_Etv5^high_distal_(10)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 MFSD2A PKHD1 PATJ

1.15e-041871135db2974e2e87ac9f1c2407a371d5ed89af09fc9b7
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D062|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

MFSD2A DUOXA1 PKHD1 PATJ SDR16C5

1.15e-0418711355df9e1f5ca32217af255e76e6fb5afa346337811
ToppCellsevere_influenza-CD4+_Tcm|severe_influenza / disease group, cell group and cell class (v2)

AIRE ATP8B2 CXCR4 PATJ PBXIP1

1.18e-041881135633e5545f49b1b864b0ffa5fc9688d270690f884
ToppCellCOVID-19-lung-Plasma_cells_PRDM1/BLIMP_hi|COVID-19 / Disease (COVID-19 only), tissue and cell type

ATP8B2 DDX11 KIF15 NUP210 SLC7A5

1.18e-041881135567b08514d9d84cbb40f9b7a679eec304f023428
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 SLCO3A1 NEDD9 PKHD1

1.21e-041891135904b8337e2cabac2f0bf5dad5598fc429581ed81
ToppCellIPF-Myeloid-ncMonocyte|Myeloid / Disease state, Lineage and Cell class

LYST TBC1D8 NEDD9 CXCR4 SSH2

1.21e-0418911355c22d2d935f7bb270260b8bc6be67b565ec401bf
ToppCellPCW_07-8.5-Epithelial-Epithelial_airway-epi_intermediate_(1)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC1A2 NRXN3 NUP210 PKHD1 PATJ

1.24e-041901135c95032bb3ee2b3d40fdf48016acb46d6f78a48a6
ToppCellTCGA-Skin-Primary_Tumor-Melanoma-Skin_Cutaneous_Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

EPPK1 CAPNS2 DUOXA1 SERPINB4 SDR16C5

1.24e-0419011353188c7bd225cbcf46a21e2fb784336cdd9665995
ToppCellTCGA-Skin-Primary_Tumor|TCGA-Skin / Sample_Type by Project: Shred V9

EPPK1 CAPNS2 DUOXA1 SERPINB4 SDR16C5

1.24e-041901135e2b26a03c6ab24d9b0f4150c47597be37767d86e
ToppCellTCGA-Skin-Primary_Tumor-Melanoma|TCGA-Skin / Sample_Type by Project: Shred V9

EPPK1 CAPNS2 DUOXA1 SERPINB4 SDR16C5

1.24e-04190113501fb45add4661bc86cd0a34fac35177907152dbb
ToppCellIPF-Myeloid-ncMonocyte|World / Disease state, Lineage and Cell class

LYST TBC1D8 NEDD9 CXCR4 SSH2

1.24e-041901135f9c2a13c7f6460e3b348581be855b7281c8f70b5
ToppCellT_cells-Effector_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

GPAT3 CXCR4 SLC7A5 PATJ PBXIP1

1.24e-0419011351af91fe0ee2c924e12f4db93c793e7af475d8f80
ToppCellFetal_29-31_weeks-Epithelial-alveolar_epithelial_cell_type_2-D150|Fetal_29-31_weeks / Lineage, Cell type, age group and donor

DOCK9 SLC1A2 MFSD2A PKHD1 PATJ

1.27e-04191113534cc997e4e5c727495f321e6807a84aa124da486
ToppCellrenal_medulla_nuclei-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 FAT3 SLCO3A1 NEDD9 PKHD1

1.27e-041911135d0e9afe7b6334dd515d3e68892efdc76347a55e5
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c04-ANXA2|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

AIRE ATP8B2 CXCR4 PATJ PBXIP1

1.27e-0419111359c747f8cc1cdce45e839b661d782e1e8cfb79578
ToppCellPBMC_fresh-frozen-Mild-Moderate_convalescent_d36-51-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Mild-Moderate_convalescent_d36-51 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK9 ATP8B2 CXCR4 PATJ PBXIP1

1.27e-041911135142f98cabf8737b28369315b3d7a0797ded88e03
ToppCellmetastatic_Brain-T/NK_cells-Exhausted_CD8+_T|T/NK_cells / Location, Cell class and cell subclass

HLA-DQA2 LYST EGR2 CXCR4 SLC7A5

1.27e-0419111352ffd40ebf1d63e61a97208ddcbeb6a86e409f9d8
ToppCellT_cells-Central_memory_CD4+_T_cells|T_cells / Immune cells in Kidney/Urine in Lupus Nephritis

DOCK9 ATP8B2 CXCR4 PATJ PBXIP1

1.27e-04191113525dd538d6a361bd3367c8a1c0dfc9e7003061af3
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ITGA2 AQP1 SLC1A2 MFSD2A PKHD1

1.30e-041921135fa2420d6117d4800f60ef6a24bcf8bf54593cd1f
ToppCellwk_20-22-Epithelial-Distal_epithelial_progenitor-epi-tip_late|wk_20-22 / Celltypes from embryonic and fetal-stage human lung

ITGA2 AQP1 SLC1A2 MFSD2A PKHD1

1.30e-04192113587b60014202633a4f6d19b09a5dd9276c2edecfb
ToppCellCOVID-19_Moderate-CD4+_Tcm|World / disease group, cell group and cell class

AIRE ATP8B2 CXCR4 PATJ PBXIP1

1.30e-0419211355f94310f1470487816fce697ffcdc2627fc66878
ToppCellEpithelial-alveolar_epithelial_cell_type_2|World / Lineage, Cell type, age group and donor

DOCK9 MFSD2A DUOXA1 PATJ SDR16C5

1.30e-04192113558c3737be7acce39fd2b91d70d6d7b2bbaa4f710
ToppCellPCW_07-8.5-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC1A2 NRXN3 NUP210 PKHD1 PATJ

1.30e-041921135d3634574b2e8d2ded6446969361b70761b331aea
ToppCellAdult-Epithelial-alveolar_epithelial_cell_type_2-D122|Adult / Lineage, Cell type, age group and donor

DOCK9 MFSD2A NRXN3 DUOXA1 SDR16C5

1.30e-04192113506013a07e3a873b1d1c0451643c528593ac32a9c
ToppCell3'-Airway_Nasal-Epithelial-Epithelial_transtional-secretory-club_cell-Club_(nasal)-Club_(nasal)_L.0.2.3.2|3' / 5'-vs-3', Tissue groups, Lineages, Lineage subclass, Cell_type2, Cell_subtype2_L4.5

SLC26A4 ITGA2 SERPINB4 UGT2A1 SDR16C5

1.33e-041931135463274f394757fb2570ae885d58e1f9fa7e60c4a
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 PTPRN ATP2B2 ATP2B4 SEZ6

1.33e-041931135be28070c049e7cb68bcd54f582226eb2f5e4bc1c
ToppCellcellseq2-Epithelial-Epithelial_Airway-Basal/Suprabasal|cellseq2 / Celltype signatures by Technology, Lineage, Lineage_subclass, Celltype_group, Cell_type2

ABCA13 ITGA2 GSDME DUOXA1 SERPINB4

1.33e-0419311357c34abdcb8839b9fb25457a79af6c5e7b9714b21
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell-Adaptive_/_Maladaptive_/_Repairing_Thick_Ascending_Limb_Cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D8 SLC15A1 PKHD1 SSH2 PATJ

1.33e-041931135f42a0f02ed00fe1bb833ff0a0640d9131bca89bd
ToppCellT_cells-Central_memory_CD4+_T_cells|World / Immune cells in Kidney/Urine in Lupus Nephritis

DOCK9 ATP8B2 CXCR4 PATJ PBXIP1

1.33e-041931135725326d7e3604736b607c19f4069c81cb4f2d20c
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-nan|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 PTPRN ATP2B2 ATP2B4 SEZ6

1.33e-0419311350c652ebe22ce5d2927599dd97ef1920547858395
ToppCellPBMC_fresh-frozen-Severe-critical_convalescent_d42-56-Lymphocytic-Lymphocytic_T-CD8-positive,_alpha-beta_T_cell-T_CD8_c02-GPR183|Severe-critical_convalescent_d42-56 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK9 ATP8B2 CXCR4 PATJ PBXIP1

1.33e-041931135c3cffafc1d40c3d7cf81034d5c51f1c78f5eb0a9
ToppCellfacs-Brain_Non-Myeloid-Cortex-24m-Neuronal-neuron|Brain_Non-Myeloid / Brain_Non-Myeloid_Brain_Myeloid - method, tissue, subtissue, age, lineage, cell ontology and free annotation

NRXN3 PTPRN ATP2B2 ATP2B4 SEZ6

1.33e-0419311358689a70a33a7c3823dc647d41ac0160e7c3ae396
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.09)

GPAT3 CRLF2 TBC1D8 CXCR4 SLC7A5

1.33e-041931135704378de39e1b6f108ab5b0ecbd594d414ec8ae4
ToppCellrenal_medulla_nuclei-CKD+DKD_normotensive-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thick_ascending_limb_epithelial_cell|CKD+DKD_normotensive / Celltypes from Cells and Nuclei per compartment and clinical group

TBC1D8 SLC15A1 PKHD1 SSH2 PATJ

1.33e-04193113542df7ed37d11fb542b4d1d714b6f87ae8e1396a6
ToppCellBAL-Control-Myeloid-cDC-cDC-cDC_5|Control / Location, Disease Group, Cell group, Cell class and sub_cluster (2021.03.01)

GPAT3 CRLF2 TBC1D8 CXCR4 SLC7A5

1.36e-04194113536f8ae4f2b3bf802f6ff0e9fc79e7f170f96ae8b
ToppCellCOVID-19_Moderate-CD4+_Tcm|COVID-19_Moderate / disease group, cell group and cell class

AIRE ATP8B2 CXCR4 PATJ PBXIP1

1.36e-041941135346ab9801366501453cedd3cb7cdfb63b7e7ddf6
ToppCellControl-Myeloid-Migratory_DC|Control / Condition, Lineage and Cell class

HLA-DQA2 GPAT3 CRLF2 TBC1D8 CXCR4

1.36e-041941135374076e60dcee83eb1814aa6b55b77668909f40b
ToppCellkidney_cells-Renal_AKI_(acute_kidney_injury)-Epithelial-Intermediate_tubule_epithelial_cell-kidney_loop_of_Henle_thin_descending_limb_epithelial_cell-Descending_Thin_Limb_Cell_Type_2|Renal_AKI_(acute_kidney_injury) / Celltypes from Cells and Nuclei per compartment and clinical group

ABCA13 AQP1 ABCB1 MAMDC2 PKHD1

1.36e-0419411358ddcaaf24cee6e30d5be52c0cbf778cfba309c53
ToppCellPBMC_fresh-frozen-Severe-critical_progression_d12-22_with-steroid-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell-T_CD4_c01-LEF1|Severe-critical_progression_d12-22_with-steroid / Compartment, severity and other cell annotations on 10x 3' data (130k)

NSA2 UGP2 ATM EIF3H PATJ

1.36e-041941135a7bfc535546d3c1a4e0cbcfeb7da816b34303350
ToppCellPCW_07-8.5-Epithelial|PCW_07-8.5 / Celltypes from embryonic and fetal-stage human lung

SLC1A2 NRXN3 NUP210 PKHD1 PATJ

1.36e-041941135f63ceedb88a9abc8644ee94adfd541e7817c1e3a
ToppCellPBMC_fresh-frozen-Mild-Moderate_progression_d12-25-Lymphocytic-Lymphocytic_T-mature_alpha-beta_T_cell|Mild-Moderate_progression_d12-25 / Compartment, severity and other cell annotations on 10x 3' data (130k)

DOCK9 SLCO3A1 UGP2 ATM PATJ

1.36e-041941135a44be2f021cfdd0fcdc698c3f04d66db7a1aa6c2
ToppCellCOVID_non-vent-Lymphocytic-T_cell|COVID_non-vent / Disease condition, Lineage, Cell class and subclass

DOCK9 ATP8B2 ATM PATJ PBXIP1

1.40e-0419511354bdedd924564a260841a9153604026b57487c83d
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 MFSD2A NUP210 PKHD1

1.40e-04195113598dd3b7d5ef587825dac052dea4d4ff883f6d4d6
ToppCellControl-Myeloid-Migratory_DC|Myeloid / Condition, Lineage and Cell class

HLA-DQA2 GPAT3 CRLF2 TBC1D8 CXCR4

1.40e-0419511359f1ad04abc6a6c5e093ea24b60732871b1fad5a4
ToppCellPCW_10-12-Epithelial-Epithelial_proliferating|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 MFSD2A NUP210 PKHD1

1.40e-041951135ce1ba5911e8a6ddb07434acc37147c38e94245ff
ToppCellPCW_13-14-Epithelial-Epithelial_alveolar-distal-epi_CTGF^high_distal_(3)|PCW_13-14 / Celltypes from embryonic and fetal-stage human lung

EPPK1 ITGA2 MFSD2A EGR2 PKHD1

1.40e-04195113562d369a8af2b76a2553bc8ff9cb89a133b060123
ToppCellPCW_05-06-Epithelial-Epithelial_proliferating-epi_proliferating3_(5)|PCW_05-06 / Celltypes from embryonic and fetal-stage human lung

EPPK1 ITGA2 SLC1A2 NUP210 PKHD1

1.40e-041951135b78db0d929be6b04055805ea5ffecc56c47ba956
ToppCellPCW_10-12-Epithelial-Epithelial_alveolar-distal|PCW_10-12 / Celltypes from embryonic and fetal-stage human lung

ITGA2 SLC1A2 MFSD2A PKHD1 PATJ

1.43e-0419611350a34a0009f479384f1994c6f977f942699a132c8
ToppCellIPF-Lymphoid-T|Lymphoid / Disease state, Lineage and Cell class

DOCK9 ITGA2 UGP2 PATJ ATP2B4

1.43e-0419611356e70c48a63d9673eb16b0847c1bd88eecc2f7a3c
ToppCell3'-GW_trimst-1.5-LargeIntestine-Endothelial|GW_trimst-1.5 / Celltypes from developing, pediatric, Crohn's, & adult GI tract

DOCK9 ITGA2 AQP1 PKHD1L1 NEDD9

1.43e-041961135629236f95c838a473b5964a49b7c1b7ad863ea12
ToppCellAT2_cells-IPF_04|World / lung cells shred on cell class, cell subclass, sample id

AQP1 MFSD2A NRXN3 SDR16C5 ATP2B4

1.46e-041971135fd7bdfa6bf5966ebc11fdd13915769429540ddbf
ToppCellLPS_anti-TNF-Epithelial_alveolar-AT_1-Differentiating_AT2|LPS_anti-TNF / Treatment groups by lineage, cell group, cell type

ITGA2 PLXNB2 NRXN3 PKHD1 PATJ

1.46e-0419711353d13a4f2e86422900ee2194e8a1fd1cf9750d5d3
ToppCellLPS_only-Epithelial_alveolar-AT_2-Differentiating_AT2|LPS_only / Treatment groups by lineage, cell group, cell type

ITGA2 PLXNB2 PGM3 NRXN3 PATJ

1.46e-0419711351a1bee8da6e04b65935c40373eaee4d6c046d9a1
ToppCellBronchus_Control_(B.)|World / Sample group, Lineage and Cell type

ABCA13 SLC26A4 ITGA2 SERPINB4 UGT2A1

1.46e-041971135b6dff2ee108813e18657e2d8cf850e2423f8c8e9
ToppCellParenchymal-10x3prime_v2-Immune_Lymphocytic-NK-ILC-T_NK-NK_CD11d|10x3prime_v2 / Cell types per location group and 10X technology with lineage, and cell group designations

NRF1 ABCB1 KIF15 EGR2 CXCR4

1.46e-04197113552246d1354c4e2b13d48c878643edf843d2b50d2
DrugTrichostatin A, from Streptomyces sp.; Down 200; 0.1uM; PC3; HT_HG-U133A

DBF4B SOCS6 BPTF KIF15 SMG9 FGF5 ATM GABPB1

3.30e-0618011383688_DN
DrugJosamycin [16846-24-5]; Up 200; 4.8uM; MCF7; HT_HG-U133A

INHBC DBF4B SLC26A4 AIRE SLC1A2 GGA3 CXCR4 SLC23A2

6.18e-0619611385692_UP
DrugCMPD167

ABCB5 ABCB1 CXCR4

9.78e-0691133CID005481119
Drugmesochlorin e6 monoethylenediamine

ABCB5 ABCB1

2.44e-0521132CID005488855
Drug6-fluorocholesterol

LYST ATM

2.44e-0521132CID000135206
Drug25-fluorocholesterol

LYST ATM

2.44e-0521132CID006454807
Drugtaxuspine C

ABCB5 ABCB1

2.44e-0521132CID005321745
Drug2,2-diphenyl-1,3-dioxolane

ABCB5 ABCB1

2.44e-0521132CID000283230
DrugRo44-5912

ABCB5 ABCB1

2.44e-0521132CID000197370
Drug8-(3,3-dimethylallyl)chrysin

ABCB5 ABCB1

2.44e-0521132CID005281903
DrugAC1L8LCS

ABCB5 ABCB1

2.44e-0521132CID000383419
Drugsulfurmycin A

ABCB5 ABCB1

2.44e-0521132CID000155836
DrugDAPDOX

ABCB5 ABCB1

2.44e-0521132CID000164413
DrugAC1Q6JJG

ABCB5 ABCB1

2.44e-0521132CID000164322
DrugYM212

ABCB5 ABCB1

2.44e-0521132CID000129980
DrugRo11-2933

ABCB5 ABCB1

2.44e-0521132CID000115215
Drugcnidiadin

ABCB5 ABCB1

2.44e-0521132CID005315980
Drugconferone

ABCB5 ABCB1

2.44e-0521132CID001757335
DrugVX-710-3

ABCB5 ABCB1

2.44e-0521132CID006450549
DrugNAc-LLY-amide

ABCB5 ABCB1

2.44e-0521132CID000443109
Drug62820-12-6

ABCB5 ABCB1

2.44e-0521132CID006449905
DrugRo 46861

AIRE ATP2B2 ATP2B4

2.53e-05121133CID000003128
DrugIC-1

ABCB5 ABCB1 PTPRN

2.53e-05121133CID000049829
DrugNSC 117356

ABCB5 POLR2G SLC19A2 SLCO3A1 ABCB1 NEDD9 SERPINB4 SLC23A2

3.20e-052461138CID000004112
DrugTMAO

DERL1 SLC26A4 ABCB5 ABCB1 UBA1 SLC23A2

4.15e-051271136CID000001145
DrugAD 288

ABCB5 ABCB1 ATM

4.16e-05141133CID000073553
DrugCMFDA

ABCB5 ABCB1 SLC15A1 CXCR4

4.58e-05401134CID000122297
Drugsilica

DERL1 ABCB5 AIRE ABCB1 PTPRN SERPINB4

4.73e-051301136CID000024261
Drugvaldecoxib

INHBC ACO1 PSMB3 PSMD5 LYST ABCB1 NEDD9 MFSD2A PTPRN UGT2A1 UBR3 ATP2B2 SEZ6

4.81e-0570511313ctd:C406224
DrugSulfacetamide sodic hydrate [6209-17-2]; Down 200; 15.8uM; MCF7; HT_HG-U133A

ITGA2 SOCS6 ATP8B2 TRIM23 NEDD9 SLC23A2 ATP2B4

5.63e-0519611371695_DN
DrugBicuculline (+) [485-49-4]; Down 200; 10.8uM; PC3; HT_HG-U133A

ERO1B DBF4B DOCK9 ATP8B2 NUP210 RHBDD3 SLC23A2

5.63e-0519611374574_DN
DrugPNU-0293363 [326823-19-2]; Down 200; 10uM; PC3; HT_HG-U133A

NRF1 DBF4B PIGG CXCR4 TAF15 PATJ GABPB1

6.00e-0519811376568_DN
DrugHydroxyzine dihydrochloride [2192-20-3]; Up 200; 9uM; MCF7; HT_HG-U133A

SLCO3A1 ATP8B2 NEDD9 CXCR4 ATM ATP2B4 CARD14

6.00e-0519811375006_UP
Drug2-chloroquinazoline

ABCB5 ABCB1

7.30e-0531132CID000074054
Drugfluoroanilinoazatoxin

ABCB5 ABCB1

7.30e-0531132CID000378896
DrugDihydrocyclosporin C

ABCB5 ABCB1

7.30e-0531132CID000196411
DrugNSC82591

ABCB5 ABCB1

7.30e-0531132CID000579054
DrugCID5317124

ABCB5 ABCB1

7.30e-0531132CID005317124
DrugNSC688503

ABCB5 ABCB1

7.30e-0531132CID000390744
DrugCp-100356

ABCB5 ABCB1

7.30e-0531132CID000196918
DrugBIBW22BS

ABCB5 ABCB1

7.30e-0531132CID000132088
DrugAC1NSGRQ

ABCB5 ABCB1

7.30e-0531132CID005333904
Drugtaxinine

ABCB5 ABCB1

7.30e-0531132CID005321702
DrugHapalosin

ABCB5 ABCB1

7.30e-0531132CID000133055
Drughaemanthidine

ABCB5 ABCB1

7.30e-0531132CID000124066
Drugtaccalonolide A

ABCB5 ABCB1

7.30e-0531132CID000441685
Drugtaccalonolide E

ABCB5 ABCB1

7.30e-0531132CID005321583
Drugiodomycin

ABCB5 ABCB1

7.30e-0531132CID000149155
DrugR101933

ABCB5 ABCB1

7.30e-0531132CID000219080
Drugmethylazatoxin

ABCB5 ABCB1

7.30e-0531132CID000148162
Drugdendroamide A

ABCB5 ABCB1

7.30e-0531132CID000177307
DrugWp159

ABCB5 ABCB1

7.30e-0531132CID003060549
DrugAC1L2Z11

ABCB5 ABCB1

7.30e-0531132CID000080228
DrugNK-250

ABCB5 ABCB1

7.30e-0531132CID000164220
Drug5-N-acetylardeemin

ABCB5 ABCB1

7.30e-0531132CID000127303
Drug1-bromo-4-chlorobutane

ABCB5 ABCB1

7.30e-0531132CID000081364
DrugD-Val-Thz

ABCB5 ABCB1

7.30e-0531132CID003082826
DrugAC1L87CG

ABCB5 ABCB1

7.30e-0531132CID000373763
Drugacridone

ABCB5 LYST ABCB1

7.69e-05171133CID000002015
DrugDMP 266

ABCB5 SLCO3A1 ABCB1 CXCR4

8.70e-05471134CID000003203
Drugeupatin

ABCB5 ABCB1

1.46e-0441132CID005317287
Drugpinoresinol dimethyl ether

ABCB1 HSD17B12

1.46e-0441132CID000073117
Drugtaxinine K

ABCB5 ABCB1

1.46e-0441132CID005321708
DrugBBR 2378

ABCB5 ABCB1

1.46e-0441132CID000219053
DrugGsh-pga1

ABCB5 ABCB1

1.46e-0441132CID005281911
Drug9-methylphenazine-1-carboxylic acid

ABCB5 ABCB1

1.46e-0441132CID004037810
DrugAHC-52

ABCB5 ABCB1

1.46e-0441132CID000164115
DrugUridine diphosphate 2-deoxyglucose

PFKL UGP2

1.46e-0441132CID000165519
DrugNK-252

ABCB5 ABCB1

1.46e-0441132CID000130889
DrugMS-073

ABCB5 ABCB1

1.46e-0441132CID000131119
DrugAC1L9UH6

ABCB5 ABCB1

1.46e-0441132CID000456215
Drugteludipine

ABCB5 ABCB1

1.46e-0441132CID006436165
Drugphellamurin

ABCB5 ABCB1

1.46e-0441132CID000193876
DrugS 9788

ABCB5 ABCB1

1.46e-0441132CID000107903
Drugerysolin

ABCB5 ABCB1

1.46e-0441132CID003080557
DrugSAHA; Up 200; 10uM; PC3; HT_HG-U133A

EPPK1 LYST TBC1D8 NEDD9 CXCR4 SLC23A2

1.49e-0416011361220_UP
DrugNSC740137

ABCB5 SLCO3A1 ABCB1 CXCR4 SLC7A5

1.64e-041031135CID000003817
Drug2-hydroxyisovaleric acid

ABCB5 LYST ABCB1 EGR2

1.73e-04561134CID000099823
DrugAC1NSKPI

ABCB5 ABCB1 ATP2B2 ATP2B4

1.86e-04571134CID005311482
Drugdoxorubicinol

ACO1 ABCB5 ABCB1

1.96e-04231133CID000083970
Drugtrichostatin A, Streptomyces sp.; Down 200; 1uM; MCF7; HT_HG-U133A

NRF1 DOCK9 SMG9 RHBDD3 PATJ GABPB1

2.21e-0417211365903_DN
DrugN-(2-hydroxypropyl)methacrylamide

ABCB5 ABCB1 CD63

2.23e-04241133CID000038622
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

LYST TRIM23 NEDD9 CXCR4 ATP2B4 PBXIP1

2.35e-0417411367179_UP
Drugacetylvalerenolic acid

ABCB5 ABCB1

2.42e-0451132CID006439585
Drugthiodicarb

ABCB5 ABCB1

2.42e-0451132CID000062155
DrugN-methylhomoveratrylamine

ABCB5 ABCB1

2.42e-0451132CID000077039
DrugAC1NSZ76

ABCB5 ABCB1

2.42e-0451132CID005320215
DrugIaci

ABCB5 ABCB1

2.42e-0451132CID000656579
DrugCyclosporin C

ABCB5 ABCB1

2.42e-0451132CID005287817
DrugAC1L7WFQ

LYST ABCB1

2.42e-0451132CID000368156
DrugSdz 280 446

ABCB5 ABCB1

2.42e-0451132CID000164287
DrugSDB-ethylenediamine

ABCB5 ABCB1

2.42e-0451132CID006438957
DrugAC1L2MCS

ABCB5 ABCB1

2.42e-0451132CID000023441
Drugpolyribosylribitol phosphate

ABCB5 ITGA2 PFKL ABCB1 UGP2

2.42e-041121135CID000002219
Drughydride

PECR PHF12 SLC26A4 ITGA2 AQP1 SLC1A2 NDUFV1 SLC15A1 UGP2 CACNA1G ATP2B2 ATP2B4 CARD14

2.58e-0483511313CID000000783
Drugglycyl-l-tyrosine

INHBC SLC15A1 CD63

2.85e-04261133CID000092829
DrugTrichostatin A, from Streptomyces sp.; Up 200; 0.1uM; MCF7; HT_HG-U133A

ERO1B DBF4B LYST NEDD9 CXCR4 PBXIP1

2.90e-0418111361535_UP
Drugtariquidar

ABCB5 SLCO3A1 ABCB1

3.19e-04271133CID000148201
DrugAC1L9GJY

PHF12 AQP1 ABCB1

3.19e-04271133CID000444581
DrugDicumarol [66-76-2]; Down 200; 11.8uM; PC3; HT_HG-U133A

ERO1B DBF4B LYST TRIM23 ATM SLC23A2

3.46e-0418711364323_DN
Diseaseserum alanine aminotransferase measurement

HECTD4 PLXNB2 MLYCD ABCB1 DDX11 TBC1D8 BPTF ZNF341 NUP210 HSD17B12 DYNLRB1 PATJ

1.08e-0486911112EFO_0004735
DiseaseCholedochal Cyst, Type I

AQP1 PKHD1

1.39e-0451112C0009439
DiseaseCholedochal Cyst, Type II

AQP1 PKHD1

1.39e-0451112C1257796
DiseaseCholedochal Cyst, Type III

AQP1 PKHD1

1.39e-0451112C1257797
DiseaseCholedochal Cyst, Type IV

AQP1 PKHD1

1.39e-0451112C1257798
DiseaseCholedochal Cyst, Type V

AQP1 PKHD1

1.39e-0451112C1257799
DiseaseCholedochal Cyst

AQP1 PKHD1

1.39e-0451112C0008340
DiseaseHailey-Hailey disease (implicated_via_orthology)

ATP2B2 ATP2B4

2.08e-0461112DOID:0050429 (implicated_via_orthology)
Diseaseprogressive supranuclear palsy

TBC1D8 ATP2B2 ATP2B4

2.16e-04311113MONDO_0019037
Diseasecysteine-rich with EGF-like domain protein 1 measurement

NUP210 ATP2B2 ATP2B4

2.37e-04321113EFO_0021870
Diseasealcohol drinking

FAT3 SLC26A4 HECTD4 INO80

2.52e-04811114EFO_0004329
DiseaseIntellectual Disability

PECR KDM3B SLC1A2 PGM3 BPTF MFSD2A UGP2 CACNA1G

2.95e-044471118C3714756
Diseaselymphocyte count

ILRUN EPPK1 SPAST SLC26A4 HECTD4 PLXNB2 LYST MFSD2A EGR2 CXCR4 SMG9 ATM SSH2 SDR16C5 ATP2B4

3.89e-04146411115EFO_0004587
Diseasehematocrit

INHBC ACO1 HECTD4 PFKL MFSD2A EGR2 PKHD1 SMG9 FGF5 SLC7A5 SSH2 DOT1L

4.30e-04101111112EFO_0004348
Diseasetemporal lobe epilepsy (implicated_via_orthology)

ABCB1 CXCR4

4.96e-0491112DOID:3328 (implicated_via_orthology)
Diseaseunderweight body mass index status

PSMB3 NRXN3

4.96e-0491112EFO_0005936
Diseasecystic fibrosis (implicated_via_orthology)

ABCB5 ABCB1

4.96e-0491112DOID:1485 (implicated_via_orthology)
DiseaseAutosomal Recessive Polycystic Kidney Disease

AQP1 PKHD1

4.96e-0491112C0085548
Diseasecancer (implicated_via_orthology)

POLD2 PSMB3 POLR2G PGM3 UGP2 ATM

5.42e-042681116DOID:162 (implicated_via_orthology)
DiseaseLiver carcinoma

ITIH3 ABCB1 MFSD2A SCAP KIF15 EGR2 ATM EIF3H

6.77e-045071118C2239176
Diseaseautosomal recessive polycystic kidney disease (biomarker_via_orthology)

AQP1 PKHD1

7.54e-04111112DOID:0110861 (biomarker_via_orthology)
Diseasewaist circumference

HECTD4 NEDD9 BPTF NRXN3 PTPRN PKHD1 HSD17B12

1.21e-034291117EFO_0004342
Diseasecoronary artery disease

ILRUN INHBC DOCK9 HECTD4 INO80 KIAA0319 NEDD9 SLC15A1 NUP210 PKHD1 HSD17B12 FGF5

1.80e-03119411112EFO_0001645
DiseaseBipolar Disorder

ABCA13 DOCK9 PFKL SLC1A2 NDUFV1 ITIH3 EGR2

2.21e-034771117C0005586
Diseasewaist-hip ratio

ILRUN HECTD4 SLCO3A1 AQP1 NEDD9 YEATS2 BPTF NRXN3 HSD17B12 DOT1L PATJ ATP2B4

2.25e-03122611112EFO_0004343
Diseaseleukemia (implicated_via_orthology)

ATM DOT1L

2.30e-03191112DOID:1240 (implicated_via_orthology)
Diseaseaspartate aminotransferase measurement, serum alanine aminotransferase measurement, low density lipoprotein triglyceride measurement, body fat percentage, high density lipoprotein cholesterol measurement, sex hormone-binding globulin measurement

BPTF PKHD1 HSD17B12 SSH2 PATJ ATP2B4

2.59e-033641116EFO_0004612, EFO_0004696, EFO_0004735, EFO_0004736, EFO_0007800, EFO_0009946
Diseasejuvenile idiopathic arthritis

ABCA13 ATP8B2 CXCR4

2.77e-03741113EFO_0002609
Diseaseesophagus squamous cell carcinoma (is_marker_for)

CXCR4 SLC7A5 ATM

2.77e-03741113DOID:3748 (is_marker_for)
Diseasecolorectal cancer (is_marker_for)

KDM3B CXCR4 SLC7A5 ATM

2.97e-031571114DOID:9256 (is_marker_for)
DiseaseNonsyndromic genetic hearing loss

SLC26A4 GSDME ATP2B2

2.98e-03761113cv:C5680182
Diseaseforced expiratory volume

DOCK9 PSMB3 INO80 PLXNB2 NRXN3 CXCR4 HSD17B12 DYNLRB1 EIF3H

2.99e-037891119EFO_0004314
Diseasebody surface area

ILRUN PSMB3 NRXN3 PKHD1 HSD17B12 DOT1L PATJ SDR16C5

3.01e-036431118EFO_0022196
DiseaseAntihypertensive use measurement

INO80 HSD17B12 FGF5 ATP2B2 ATP2B4

3.33e-032651115EFO_0009927
DiseaseQRS duration, response to sulfonylurea

DOCK9 SLC15A1

3.37e-03231112EFO_0005055, EFO_0007922
DiseaseDisease Exacerbation

ABCA13 NDUFV1 ABCB1 TAF15

3.55e-031651114C0235874
Diseaselung squamous cell carcinoma (is_implicated_in)

SLC7A5 ATM

3.67e-03241112DOID:3907 (is_implicated_in)

Protein segments in the cluster

PeptideGeneStartEntry
ITQGDLVAVGVLSGN

ACO1

521

P21399
LSQSVIDGVTVLGGQ

PGM3

136

O95394
EGQGTEVVQGVLLGL

EIF3H

56

O15372
SIIFLTGIVGNGLVI

CXCR4

46

P61073
KGDILTVIEQNTGGL

NEDD9

26

Q14511
GILSTVQGITGLRIV

BPIFB4

216

P59827
TILAIDIAQIQGATG

ABCB5

796

Q2M3G0
GQGVAAAVQLLVTLS

ERO1B

11

Q86YB8
GGIVGIQTKTVQVSA

GSDME

181

O60443
GQGLGIEIIGTLQLV

AQP1

136

P29972
ISSVGTGNLVVNLLV

ABCA13

1696

Q86UQ4
DLGSGVGQVVLQVAA

DOT1L

161

Q8TEK3
GVQGIIVVNTEGIPI

DYNLRB1

16

Q9NP97
LTVVIQGQGQTTGQL

BPTF

2291

Q12830
VGVNSQTGIIFTLLG

ATP2B2

276

Q01814
VNSQTGIILTLLGVN

ATP2B4

276

P23634
VEGILIQQVFESGGS

AIRE

206

O43918
IGVGISGQEGIQAVL

ATP8B2

846

P98198
GGGSLVITQIGLQDA

IGDCC4

386

Q8TDY8
EVNVSELGLVTQGGK

NSA2

221

O95478
LGGDLAGVNVIQVAT

RCC1L

276

Q96I51
IFVQGLGEGVSTDQV

TAF15

236

Q92804
VGDVSILINNAGIVT

SDR16C5

116

Q8N3Y7
GIINIVSAGILQGVT

EGR2

111

P11161
QIDIGGGVVVNITQE

INO80

426

Q9ULG1
IGLAGLATDVQTVAQ

PSMB3

51

P49720
VFTVVGNLGLITLIG

OR8B4

36

Q96RC9
ILIEGVLGQGNTASI

MAMDC2

141

Q7Z304
ITQNIANLGTGIIIS

ABCB1

836

P08183
VGVGAQLVLSQTIIQ

CD63

31

P08962
LAIGNGTVSGLVQAV

NUP210

1131

Q8TEM1
GIVVGTVFIIQGLRS

HLA-DQA2

231

P01906
LEAQTGLQILQTGVG

PTPRN

541

Q16849
LTSLGGNATIAVIVQ

OR10V1

36

Q8NGI7
VEGIQVLGTGNLIIS

IGDCC3

281

Q8IVU1
VLGTGNLIISDVTVQ

IGDCC3

286

Q8IVU1
GQVITALVDVGNGKQ

KIF15

296

Q9NS87
LIGVGQSVTAVGRII

MFSD9

411

Q8NBP5
LEGQVAQSSVILGGA

INHBC

201

P55103
SSGGQQVITIVTDGI

GABPB1

266

Q06547
QVITIVTDGIQLGNL

GABPB1

271

Q06547
ISLTQQGLQGVELGT

MLYCD

291

O95822
SLLGTQLLVDVVTGQ

POLD2

211

P49005
ITILGSNLGVQAGDI

PLXNB2

821

O15031
LSVSNIIQLGGTIIG

PFKL

71

P17858
LQGQVAIVTGGATGI

PECR

16

Q9BY49
GKIGVVFNIGTVDIS

NRXN3

1151

Q9Y4C0
ATLAEATLQGGGQIV

NRF1

416

Q16656
IGGSVINELIGNLVG

DERL1

166

Q9BUN8
AGKTLEQVGQGIVAS

KDM3B

406

Q7LBC6
TLLNGVAIIVGTIIG

SLC7A5

51

Q01650
IIEGQVINGEVATLT

GGA3

296

Q9NZ52
LGQGGAAEGVQIQII

CRLF2

21

Q9HC73
QERGQVTGALLLSVV

DDX11

761

Q96FC9
GISGSIGVVASINEQ

HECTD4

1756

Q9Y4D8
TLGEQIFSIEGTVQG

ITGA2

356

P17301
EGLRTIGVTTNGINL

MOCS1

146

Q9NZB8
VLGGNQTLTVNVEGT

NUP54

216

Q7Z3B4
TVEVLGTVLGTAIQG

MFSD2A

201

Q8NA29
GTVLGTAIQGQIVGQ

MFSD2A

206

Q8NA29
LEIFAVSQGIVGIRG

FGF5

121

P12034
EEGTVLSVGGQVNLL

ATM

3021

Q13315
ILSVEVGGLLGVTQQ

ILRUN

176

Q9H6K1
EQISVIGGNLTGIFI

CARD14

581

Q9BXL6
ISVSQLIADVVGIGG

DOCK9

1526

Q9BZ29
EIVGQQGGGLSVLRT

CACNA1G

821

O43497
IGISLLVIGTTLVGQ

GPAT3

166

Q53EU6
LTGAIQQLGGVIEGF

DBF4B

66

Q8NFT6
NGVVLDGGQIVTVSL

SLC1A2

416

P43004
NIGGIVGGIVNFISE

CAPNS2

36

Q96L46
NKGGIFVIEQETGTI

FAT3

2751

Q8TDW7
GLAGLEIGILVNNVG

HSD17B12

121

Q53GQ0
GVSINVIAGGLENGI

LYST

3716

Q99698
ILQGIDLIVVAQTGT

DDX53

256

Q86TM3
SADIGLQVGLGGVNI

DUOXA1

96

Q1HG43
LQVGLGGVNITLTGT

DUOXA1

101

Q1HG43
VAVGNIIVLIVAGAG

SLC15A1

626

P46059
LVGFTVGSVLGQILV

SLC19A2

166

O60779
LGVISDNLLVTGGQG

SCAP

1206

Q12770
VLQGIDLIGVAQTGT

DDX43

276

Q9NXZ2
NQILIVIGETGSGKT

DHX8

581

Q14562
NNILQTDIVTGVGVA

NUP210L

1516

Q5VU65
GQTGLDAIVTQLLGQ

RNF115

181

Q9Y4L5
IGAQVLLGIGATPVQ

SLCO3A1

181

Q9UIG8
QDAVTGLTVNGQITG

ITIH3

681

Q06033
ALVQAQTGLGTAAVI

NDUFV1

341

P49821
GKIGVVFNIGTVDIS

NRXN3

146

Q9HDB5
GIRLLEAQIATGGVI

EPPK1

716

P58107
GIRLLEAQIATGGVI

EPPK1

2871

P58107
GIRLLEAQIATGGVI

EPPK1

3936

P58107
GGLQNHTVGIIVKTE

PHF12

591

Q96QT6
QTDVLVVGVLGLQGT

SMG9

201

Q9H0W8
NISNIAGGETLVIGV

PKHD1

1116

P08F94
LEKGIAVIVTGQGEQ

SPAST

156

Q9UBP0
DVQEVGTAIQVAGIG

CLDN34

171

H7C241
VSLLVGGQVGTETLV

RHBDD3

356

Q9Y3P4
GGLNVIQLETAVGAA

UGP2

361

Q16851
TVLAVQSLLDGQGAV

ZNF341

16

Q9BYN7
VQGDLQETTVVTGLG

PBXIP1

101

Q96AQ6
IAVTTIDNIGAGVIQ

POLR2G

46

P62487
IESISQGVGQIQLKG

SSH2

756

Q76I76
TGITGIDQVLNVLLT

SLC23A2

541

Q9UGH3
QEGQGSILETITLIQ

SLC26A4

736

O43511
TFIVQGVTLGAEGII

SLC25A46

166

Q96AG3
NVSLGISIVGGQTVI

PATJ

1076

Q8NI35
TTLLLQIGEVGQRGS

TBC1D8

1021

O95759
VAEVVSQGAGIGIQG

SEZ6

196

Q53EL9
GTIGNDTTLVLVNAI

SERPINB4

166

P48594
LAQEGSEVNVIGIGT

NAPRT

366

Q6XQN6
AENILITDGGVLQIG

PKHD1L1

2236

Q86WI1
LESGTLGTKGNVQVV

UBA1

596

P22314
TGLVVLLQASSVLGQ

UBR3

1251

Q6ZT12
VDTVGILGSNVEGKQ

PSMD5

316

Q16401
LVGIVQHIEGGEQIV

TRIM23

251

P36406
VIVSVLTNVLVGGNT

PIGG

521

Q5H8A4
SGVLIAGGENGNIIL

SEC31A

86

O94979
QISLIGTTLGGNVLI

UGT2A1

11

P0DTE4
VDQSVNGLLIGTTGV

SOCS6

281

O14544
QVVTQGVAKAIVSGG

YEATS2

691

Q9ULM3
GLVELTLQVGVGQLT

KIAA0319

816

Q5VV43